Academic literature on the topic 'Urge to cough'

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Journal articles on the topic "Urge to cough"

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Hilton, Emma, Imran Satia, Kimberley Holt, Ashley A. Woodcock, John Belcher, and Jaclyn A. Smith. "The effect of pain conditioning on experimentally evoked cough: evidence of impaired endogenous inhibitory control mechanisms in refractory chronic cough." European Respiratory Journal 56, no. 6 (July 23, 2020): 2001387. http://dx.doi.org/10.1183/13993003.01387-2020.

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The pathophysiology of refractory chronic cough (RCC) is unclear. We hypothesised that endogenous inhibitory control mechanisms, such as those activated by noxious stimuli inducing pain (conditioned pain modulation) may be capable of inhibiting coughing and urge to cough evoked by inhaled capsaicin. Furthermore, these mechanisms may be impaired in patients with RCC.The objective was to investigate the effects of pain on cough and urge to cough in healthy volunteers and RCC patients. Healthy volunteers and RCC patients underwent a randomised, controlled, four-way crossover study comparing the effect of four interventions on capsaicin-evoked coughing and urge to cough. The interventions comprised immersing a hand in 1) noxious cold water; 2) warm water; 3) warm water, but subjects were instructed to voluntarily supress coughing; and 4) no intervention. The co-primary outcomes were numbers of evoked coughs and urge to cough scores.20 healthy volunteers (mean±sd age 50.1±14.2 years, male:female 10:10) and 20 RCC patients (age 60.1±7.9 years, male:female 9:11) participated. Overall, noxious cold water reduced capsaicin-evoked urge-to-cough scores and cough numbers compared with warm water (1.6 (95% CI 1.3–2.0) versus 2.2 (1.8–2.6), p<0.001 and 4.8 (3.7–6.2) coughs versus 7.9 (6.7–9.5) coughs, p<0.001, respectively). Healthy volunteers and RCC patients demonstrated similar reductions in the urge to cough during noxious cold-water immersion, but noxious cold water and voluntary suppression interventions were less effective at reducing capsaicin-evoked cough in RCC patients than in healthy volunteers (p=0.041).Endogenous inhibitory control mechanisms, specifically those activated by pain, can reduce both coughing and the urge to cough. Impairment of endogenous inhibitory control mechanisms may contribute to excessive coughing in RCC.
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Sato, Ryuhei, Peijun Gui, Kumiko Ito, Masahiro Kohzuki, and Satoru Ebihara. "Effect of Short-Term Exposure to High Particulate Levels on Cough Reflex Sensitivity in Healthy Tourists: A Pilot Study." Open Respiratory Medicine Journal 10, no. 1 (December 30, 2016): 96–104. http://dx.doi.org/10.2174/1874306401610010096.

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Background: Previous studies have reported a relationship between particulate air pollution and respiratory symptoms or decline in lung function, but information about acute effects of short-term exposure to airborne particulate matter (PM) on cough and pulmonary function is scarce. Objective: To investigate the effect of short-term exposure to high concentrations of PM on the cough reflex threshold, urge-to-cough, pulmonary function, and cough-related quality of life in a group of healthy non-resident volunteers visiting Beijing, China. Methods: Seventeen healthy residents of Sendai, Japan, who planned to attend a meeting in Beijing, were recruited. We checked local air quality and measured cough reflex thresholds, urge-to-cough, pulmonary function, and Leicester Cough Questionnaire-acute (LCQ-acute) scores in the volunteers before, during, and after their trip to Beijing. Results: The PM2.5 and PM10 concentrations in Beijing were significantly higher than those in Japan on the measurement days. Cough reflex thresholds, expressed as nebulized citric acid concentrations required to induce ≥ 2 and ≥ 5 coughs, were significantly lower during the stay in Beijing than before or after the visit. Vital capacity, forced expiratory volume in one second (FEV1), forced vital capacity (FVC), and FEV1/FVC were significantly lower during the stay in Beijing than before the trip. Similarly, the urge-to-cough threshold was significantly lower during the stay in Beijing than after the trip, as was the total LCQ-acute score. Conclusion: We tentatively concluded that short-term exposure to high PM concentrations may have adverse effects on cough reflex and urge-to-cough thresholds, pulmonary function, and cough-related quality of life.
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Ebihara, Takae, Peijun Gui, Chika Ooyama, Koichi Kozaki, and Satoru Ebihara. "Cough reflex sensitivity and urge-to-cough deterioration in dementia with Lewy bodies." ERJ Open Research 6, no. 1 (January 2020): 00108–2019. http://dx.doi.org/10.1183/23120541.00108-2019.

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Cough, an important respiratory symptom, predominantly involves the brainstem and the urge-to-cough (UTC) is modulated by the cerebral cortex. Lewy body disease is associated with decreased cough reflex sensitivity and central respiratory chemosensitivity. Additionally, the insula, associated with the UTC, shows decreased activation and atrophy in dementia with Lewy bodies (DLB). We investigated the relationships between cognition and cough reflex and the UTC and compared the differences in responses of patients with DLB and other dementia subtypes.We conducted a cross-sectional study within a geriatric ward of a university hospital involving elderly patients diagnosed with Alzheimer's disease (AD), DLB, or non-dementia (controls). The cough reflex sensitivities were estimated based on the lowest concentrations of inhaled citric acid that could induce ≥2 coughs (C2) or ≥5 coughs (C5). Subjects were asked to rate the UTC based on the threshold concentrations (Cu) using the modified Borg scale.C2, C5 and Cu were negatively correlated with cognitive function in female participants but not in males (p<0.01). The cough reflex sensitivities expressed as C2 and C5 were significantly higher in the DLB group than in the AD and control groups (p<0.01 adjusted for gender). The UTC threshold expressed as Cu was also significantly higher in the DLB group, while the UTC log–log slope was less responsive in the DLB group than in the other groups.The cough reflex sensitivity and perceived UTC deteriorated in the DLB group more than in the other groups. This result might be valuable in treating patients with DLB.
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Bolser, Donald C. "A streetcar named urge-to-cough." Journal of Applied Physiology 108, no. 5 (May 2010): 1030–31. http://dx.doi.org/10.1152/japplphysiol.00177.2010.

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Davenport, Paul W. "Urge-to-Cough: What Can It Teach Us About Cough?" Lung 186, S1 (October 22, 2007): 107–11. http://dx.doi.org/10.1007/s00408-007-9045-7.

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Mannini, Claudia, Guja Bernacchi, Viola Bonti, Elenia Cinelli, Donatella Mutolo, Giovanni A. Fontana, and Federico Lavorini. "Somatic points for cough and urge to cough in chronic coughers." Respiratory Medicine 200 (August 2022): 106929. http://dx.doi.org/10.1016/j.rmed.2022.106929.

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Janssens, Thomas, Lieven Dupont, and Omer Van den Bergh. "Conditioned cough and urge-to-cough in a category learning task." Biological Psychology 129 (October 2017): 377. http://dx.doi.org/10.1016/j.biopsycho.2017.08.026.

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Kum, Elena, Gordon H. Guyatt, Caroline Munoz, Suzanne Beaudin, Shelly-Anne Li, Rayid Abdulqawi, Huda Badri, et al. "Assessing cough symptom severity in refractory or unexplained chronic cough: findings from patient focus groups and an international expert panel." ERJ Open Research 8, no. 1 (January 2022): 00667–2021. http://dx.doi.org/10.1183/23120541.00667-2021.

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BackgroundCough symptom severity represents an important subjective end-point to assess the impact of therapies for patients with refractory or unexplained chronic cough (RCC/UCC). As existing instruments assessing the severity of cough are neither widely available nor tested for measurement properties, we aim to develop a new patient-reported outcome measure addressing cough severity.ObjectiveThe aim of this study was to establish items and domains that would inform development of a new cough severity instrument.MethodsThree focus groups involving 16 adult patients with RCC/UCC provided data that we analysed using directed content analysis. Discussions led to consensus among an international panel of 15 experts on candidate items and domains to assess cough severity.ResultsThe patient focus group provided 48 unique items arranged under broad domains of urge-to-cough sensations and cough symptom. Feedback from expert panel members confirmed the appropriateness of items and domains, and provided an additional subdomain related to cough triggers. The final conceptual framework comprised 51 items in the following domains: urge-to-cough sensations (subdomains: frequency and intensity) and cough symptom (subdomains: triggers, control, frequency, fit/bout duration, intensity, quality and associated features/sequelae).ConclusionsConsensus findings from patients and international experts established domains of urge-to-cough and cough symptom with associated subdomains and relevant items. The results support item generation and content validity for a novel patient-reported outcome measure for use in health research and clinical practice.
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Kum, Elena, Gordon H. Guyatt, Tahira Devji, Yuting Wang, Layla Bakaa, Lucy Lan, Eva Liu, et al. "Cough symptom severity in patients with refractory or unexplained chronic cough: a systematic survey and conceptual framework." European Respiratory Review 30, no. 161 (July 13, 2021): 210104. http://dx.doi.org/10.1183/16000617.0104-2021.

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BackgroundCough severity represents an important subjective endpoint in assessing the effectiveness of therapies for patients with chronic cough. Although cough-specific quality of life questionnaires exist, a widely available cough severity instrument with established measurement properties remains unavailable.AimsTo identify and summarise the results of studies reporting on the experience of patients with chronic cough and, in the process, develop a conceptual framework to inform development of a patient-reported outcome measurement (PROM) addressing cough severity.ResultsWe identified 61 eligible studies reporting on patient experience with chronic cough. Studies provided 82 potential items, of which 43 proved unique and relevant to cough severity. The urge-to-cough sensation and the cough symptom itself represented broad domains of cough severity. Two subdomains under urge-to-cough included frequency (1 item) and intensity (1 item). Five subdomains under cough symptoms included control (2 items), frequency (6 items), bout duration (1 item), intensity (8 items), and associated features/sequelae (24 items).ConclusionsOur systematic survey and conceptual framework identified items and domains of cough severity in patients with refractory or unexplained chronic cough. The results support item generation and content validity for a PROM assessing cough severity.
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Hilton, Emma, Paul Marsden, Andrew Thurston, Stephen Kennedy, Samantha Decalmer, and Jaclyn A. Smith. "Clinical features of the urge-to-cough in patients with chronic cough." Respiratory Medicine 109, no. 6 (June 2015): 701–7. http://dx.doi.org/10.1016/j.rmed.2015.03.011.

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Dissertations / Theses on the topic "Urge to cough"

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Rajappa, Akila Theyyar. "Psychophysical Evaluation of Descriptors and Tools for Measurement of Urge-to-Cough Sensation in Healthy Young Adults (HYA)." Thesis, 2019. https://doi.org/10.7916/d8-gkh0-cg55.

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The studies contained in this dissertation were driven by a desire to improve the methods for sensory testing of cough for clinical research and practice. Two scientific gaps in the cough evaluation literature were identified and investigated using two specific studies on healthy young adult participants. The first study focused on validating an appropriate descriptor for cough sensations (Chapter 2) and the second study (Chapter 3) focused on evaluating magnitude estimation tools to measure cough sensations. The findings of this dissertation make several unique contributions to the cough literature. The first study systematically compared two descriptive responses to cough stimuli (i.e., capsaicin) within subjects in terms of both cough sensory and cough motor outcomes. Findings revealed two types of descriptive responses for capsaicin stimuli, warm/burn and urge-to-cough (UTC). The UTC descriptor was, however, more sensitive and a valid predictor of cough response. The second study systematically compared two magnitude estimation tools, the Modified Borg Scale (MBS) and the generalized Labeled Magnitude Scale (gLMS) to measure the UTC sensations. Findings revealed that both tools were reliable and valid in detecting UTC sensations and predicting cough response. However, a differential effect to detection of UTC sensations across neighboring stimuli concentrations were demonstrated by the two tools. This dissertation provides the first set of normative reference values for UTC responses across a wide range of sensory continua using the conventional metric, the MBS, and an additional metric, the gLMS. Limitations are acknowledged and future work is suggested.
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Book chapters on the topic "Urge to cough"

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Davenport, P. W. "Clinical Cough I: The Urge-To-Cough: A Respiratory Sensation." In Pharmacology and Therapeutics of Cough, 263–76. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-79842-2_13.

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Milward, John. "Something in the Air." In Americanaland, 100–112. University of Illinois Press, 2021. http://dx.doi.org/10.5622/illinois/9780252043918.003.0008.

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This chapter explores Joni Mitchell's music. After Mitchell played “Both Sides Now” for Neil Young, he offered his coming-of-age tune, “Sugar Mountain,” which inspired her to write “The Circle Game.” She met and married folk singer Chuck Mitchell; they lived in Detroit and played coffeehouses. Tom Rush, a folk singer from Cambridge, Massachusetts, crashed on their couch and left with a song for his next album, Mitchells's “Urge for Going.” Rush titled his album The Circle Game and included a third Mitchell song, “Tin Angel,” alongside original compositions from two other little-known singer-songwriters: James Taylor (“Something in the Way She Moves” and “Sunshine Sunshine”) and Jackson Browne (“Shadow Dream Song”). This new crop of songwriters wrote from personal experience and was as strongly influenced by contemporary music as by traditional folk songs. But to varying degrees Bob Dylan touched them all.
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Hamkins, SuEllen. "Finding Happiness: Rising from Despair and Turning Away from Anxiety." In The Art of Narrative Psychiatry. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780199982042.003.0015.

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“Anxiety is ruining my life,” Addie Markiewicz had said to me at her first appointment at age sixteen. Now, four years later, she entered my office, dropped her backpack on the floor, plopped down comfortably on the couch, picked up one of my blue throw pillows and began fiddling with the zipper. A junior in college, Addie had long, dark hair, blue eyes, fair skin, wholesome good looks, and a dry, at times mischievous sense of humor. In our weekly sessions, she could be alternately reticent and forthcoming. A gifted student with lots of friends, she volunteered at a daycare facility for children with special needs and was a respected and beloved babysitter for several families in the area. She had helped to form an advocacy group at her college for students who were dealing with mental health challenges. She had a loving relationship with her parents, whom she called her “best friends,” and her life had been free of any major trauma; on the contrary, her childhood had been characterized by a loving, supportive family and a close-knit community of which she was a cherished member, many of whom shared her Polish American heritage. For the first three years of our work together, I met with Addie for twenty minutes every week or two and she also met with a psychotherapist. After he moved out of the area, I became her primary psychotherapist, meeting with her weekly for fifty minutes. She had made great strides in overcoming profound despair, an ongoing sense of unreality, severe anxiety, and unwanted compulsive urges that had dogged her since she was twelve, but at times one or more of these problems flared up again, and we were still chipping away at them, working toward a fuller recovery. From our first appointment, she had identified a problem of feeling an overwhelming urge to spend hours and hours on her homework until it was flawless, accompanied by a keen anxiety lest there were any mistakes.
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Kopley, Emily. "A Room of One’s Own, Woolf’s “little book on poetry”." In Virginia Woolf and Poetry, 107–35. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780198850861.003.0004.

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In several essays concurrent with her major experimental works of the 1920s, Woolf proclaims that the novel will usurp the tools and the place of poetry. Most important among these essays is the book-length A Room of One’s Own (1929). Here Woolf identifies the lack of poet foremothers available as models to women writers. She urges young women to fill this gap by writing not poetry per se, but rather prose whose greatness qualifies it as “poetry.” Woolf wants to gain for prose, and by extension women writers, the prestige historically accorded to verse. This chapter sketches the historic link among English Studies, poetry, and patriarchy. This link contributed to Woolf’s vision of the novel as the democratic, feminist alternative to poetry. It also spurred her subtle challenge in A Room of One’s Own to Sir Arthur Quiller-Couch, who had doubted women’s ability to write poetry. This chapter concludes by considering the real women poets who inspired Woolf’s fiction of Judith Shakespeare.
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Conference papers on the topic "Urge to cough"

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Solomon, A., PS P. Cho, H. Fletcher, IS Patel, CJ Jolley, RD Turner, and SS Birring. "P103 The urge to cough in copd." In British Thoracic Society Winter Meeting 2017, QEII Centre Broad Sanctuary Westminster London SW1P 3EE, 6 to 8 December 2017, Programme and Abstracts. BMJ Publishing Group Ltd and British Thoracic Society, 2017. http://dx.doi.org/10.1136/thoraxjnl-2017-210983.245.

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Rhoton, WA, A. Negassa, and PV Dicpinigaitis. "Capsaicin-Induced Urge-to-Cough Sensation: Relationship to Cough Reflex Sensitivity." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a5759.

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Ebihara, S., S. Yamanda, T. Ebihara, M. Asada, M. Yamasaki, T. Asamura, and H. Arai. "Impaired Urge-to-Cough in Elderly Patients with Aspiration Pneumonia." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a5755.

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Dicpinigaitis, Peter, Rajani Bhat, and William Rhoton. "Effect Of Acute Viral Upper Respiratory Tract Infection On Cough Reflex Sensitivity And The Urge-to-Cough Sensation." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a5546.

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Takeda, Tomoshi, Akio Niimi, Tadashi Ino, Hideki Inoue, Isao Ito, Hisako Matsumoto, Ryusuke Nakai, Takashi Azuma, and Michiaki Mishima. "Investigation Of Central Cough Mechanisms Using Functional Magnetic Resonance Imaging: Representation Of Citric Acid-evoked Urge-to-cough In The Human Brain." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a5558.

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