To see the other types of publications on this topic, follow the link: Urethral.
Journal articles on the topic 'Urethral'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 journal articles for your research on the topic 'Urethral.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.
1
Allawi, Bahir Sabah, Alaa H. Al-Farhan, and Rafid F. Al-Hussaini. "Urethral Extensibility Applied to Urethral Advancement." Open Access Macedonian Journal of Medical Sciences 8, B (September 14, 2020): 1023–28. http://dx.doi.org/10.3889/oamjms.2020.4810.
Full textAbstract:
BACKGROUND: The male urethra in humans has a large capacity to extend under traction. This property is the main principle of the urethral advancement technique.
AIM: We aimed to determine the safe limits of urethral mobilization and extensibility for reconstructive surgery of distal to midshaft hypospadias by applying urethral extensibility on the urethral advancement technique. Also, we wanted to evaluate the variable application of the gap-to-urethra (G:U) ratio from a cadaver to a live human body.
METHODS: From November 2004 to February 2006, 20 boys aged from 2 to 16 years old underwent repair of midshaft to glanular hypospadias by urethral advancement technique. The ratio of G:U proposed for a safe limit of urethral extensibility (measured from normal, fresh human cadaveric urethras) applied to know if its application can help in decreasing the rate of late complications. The mean follow-up period was 10 months, which ranged from 4 to 16 months.
RESULTS: Late complications were as follows: 25% meatal retraction (MR), 15% meatal stenosis (MS), and 5% fistula. Besides, MR and MS late complications associated with urethral mobilization of G:U ratio of less than 73%.
CONCLUSION: The more the approximation in the application of the G:U ratio, the less the rate of MS and MR. Besides, urethral mobilization to the base of the penis helps to decrease the frequency of MS and MR. Furthermore, the type of complication, MR or MS, in urethral advancement correlates with the extent of urethral mobilization.
2
Prantil-Baun, Rachelle, William C. de Groat, Minoru Miyazato, Michael B. Chancellor, Naoki Yoshimura, and David A. Vorp. "Ex vivo biomechanical, functional, and immunohistochemical alterations of adrenergic responses in the female urethra in a rat model of birth trauma." American Journal of Physiology-Renal Physiology 299, no. 2 (August 2010): F316—F324. http://dx.doi.org/10.1152/ajprenal.00299.2009.
Full textAbstract:
Birth trauma and pelvic injury have been implicated in the etiology of stress urinary incontinence (SUI). This study aimed to assess changes in the biomechanical properties and adrenergic-evoked contractile responses of the rat urethra after simulated birth trauma induced by vaginal distension (VD). Urethras were isolated 4 days after VD and evaluated in our established ex vivo urethral testing system that utilized a laser micrometer to measure the urethral outer diameter at proximal, middle, and distal positions. Segments were precontracted with phenylephrine (PE) and then exposed to intralumenal static pressures ranging from 0 to 20 mmHg to measure urethral compliance. After active assessment, the urethra was rendered passive with EDTA and assessed. Pressure and diameter measurements were recorded via computer. Urethral thickness was measured histologically to calculate circumferential stress-strain response and functional contraction ratio (FCR), a measure of smooth muscle activity. VD proximal urethras exhibited a significantly increased response to PE compared with that in controls. Conversely, proximal VD urethras had significantly decreased circumferential stress and FCR values in the presence of PE, suggesting that VD reduced the ability of the proximal segment to maintain smooth muscle tone at higher pressures and strains. Circumferential stress values for VD middle urethral segments were significantly higher than control values. Histological analyses using antibodies against general (protein gene product 9.5) and sympathetic (tyrosine hydroxylase) nerve markers showed a significant reduction in nerve density in VD proximal and middle urethral segments. These results strongly suggest that VD damages adrenergic nerves and alters adrenergic responses of proximal and middle urethral smooth muscle. Defects in urethral storage mechanisms, involving changes in adrenergic regulation, may contribute to stress urinary incontinence induced by simulated birth trauma.
3
Prantil, Rachelle L., Ron J. Jankowski, Yasuhiro Kaiho, William C. de Groat, Michael B. Chancellor, Naoki Yoshimura, and David A. Vorp. "Ex vivo biomechanical properties of the female urethra in a rat model of birth trauma." American Journal of Physiology-Renal Physiology 292, no. 4 (April 2007): F1229—F1237. http://dx.doi.org/10.1152/ajprenal.00292.2006.
Full textAbstract:
Stress urinary incontinence (SUI) is the involuntary release of urine during sudden increases in abdominal pressures. SUI is common in women after vaginal delivery or pelvic trauma and may alter the biomechanical properties of the urethra. Thus we hypothesize that injury due to vaginal distension (VD) decreases urethral basal tone and passive stiffness. This study aimed to assess the biomechanical properties of the urethra after VD in the baseline state, where basal muscle tone and extracellular matrix (ECM) are present, and in the passive state, where inactive muscle and ECM are present. Female rat urethras were isolated in a rat model of acute SUI induced by simulated birth trauma. Our established ex vivo system was utilized, wherein we applied intraluminal static pressures ranging from 0 to 20 mmHg. Outer diameter was measured via a laser micrometer. Measurements were recorded via computer. Urethral thickness was assessed histologically. Stress-strain responses of the urethra were altered by VD. Quantification of biomechanical parameters indicated that VD decreased baseline stiffness. The passive peak incremental elastic modulus of the distal segment in VD urethras was less than for controls (1.84 ± 0.67 vs. 1.19 ± 0.70 × 106 dyne/cm2, respectively; P = 0.016). An increase was noted in passive low-pressure compliance values in proximal VD urethras compared with controls (9.44 ± 2.43 vs. 4.62 ± 0.60 mmHg−1, respectively; P = 0.04). Biomechanical analyses suggest that VD alters urethral basal tone, proximal urethral compliance, and distal stiffness. Lack of basal smooth muscle tone, in combination with these changes in the proximal and distal urethra, may contribute to SUI induced by VD.
4
Culenova, Martina, Stanislav Ziaran, and Lubos Danisovic. "Cells Involved in Urethral Tissue Engineering: Systematic Review." Cell Transplantation 28, no. 9-10 (June 25, 2019): 1106–15. http://dx.doi.org/10.1177/0963689719854363.
Full textAbstract:
The urethra is part of the lower urinary tract and its main role is urine voiding. Its complex histological structure makes urethral tissue prone to various injuries with complicated healing processes that often lead to scar formation. Urethral stricture disease can affect both men and women. The occurrence of this pathology is more common in men and thus are previous research has been mainly oriented on male urethra reconstruction. However, commonly used surgical techniques show unsatisfactory results because of complications. The new and progressively developing field of tissue engineering offers promising solutions, which could be applied in the urethral regeneration of both men´s and women´s urethras. The presented systematic review article offers an overview of the cells that have been used in urethral tissue engineering so far. Urine-derived stem cells show a great perspective in respect to urethral tissue engineering. They can be easily harvested and are a promising autologous cell source for the needs of tissue engineering techniques. The presented review also shows the importance of mechanical stimuli application on maturating tissue. Sufficient vascularization and elimination of stricture formation present the biggest challenges not only in customary surgical management but also in tissue-engineering approaches.
5
Chakraborty, Abhi Kumar, Sajal Kumar Majumdar, Mirza Kamrul Zahid, Ipsita Biswas, and Poritosh Palit. "Limited Urethral Mobilization Technique in Distal Hypospadias Repair : An Overview." Chattagram Maa-O-Shishu Hospital Medical College Journal 16, no. 1 (December 26, 2017): 37–41. http://dx.doi.org/10.3329/cmoshmcj.v16i1.34985.
Full textAbstract:
Background: Fistula formation is the most common complication with various rates among different techniques of hypospadias repair. The urethral advancement as an one stage technique for repair of hypospadias is considered a good technique. As no new urethral tube is constructed there is no risk of fistula. We assess the outcomes of the Limited Urethral Mobilization (LUM) technique in distal hypospadias repair.Methods: Our study included 20 patients aged upto 12 years who were treated with Limited urethral mobilization technique for distal hypospadias in Shaheed Suhrawardy Medical College Hospital from December 2014 to December 2015. The urethra proximal to the meatus was mobilized for a distance sufficient to allow it to reach the glans tip without tension. Then the urethra was placed in the glanular bed and glanular reconstruction was performed.Results: Three-fold urethral mobilization was sufficient for construction of tension-free urethra-glanular anastomosis. Cosmetically normal looking circumcised penis with ventrally slit meatus achieved in all but one subcoronal case where the most distal of the glans approximation sutures disrupted leading to a minor detachment in the glans. The minor complications includes preputial edema in one patient, two patients had wound infection, one had meatal stenosis which was treated with gentle dilatations. Postoperative urethro cutaneous fistula, retraction of the urethral meatus or recurrent chordee were not observed.Conclusion: Distal hypospadias repair with the LUM technique can be effective with satisfactory cosmetic and functional results. There is no chance for development of urethro cutaneous fistula, a major postoperative complication of other surgical techniques of creating a neourethra. Postoperative management is simple and a brief hospital stay is sufficient.Chatt Maa Shi Hosp Med Coll J; Vol.16 (1); Jan 2017; Page 37-41
6
Le Feber, Joost, Els Van Asselt, and Ron Van Mastrigt. "Neurophysiological modeling of voiding in rats: urethral nerve response to urethral pressure and flow." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 274, no. 5 (May 1, 1998): R1473—R1481. http://dx.doi.org/10.1152/ajpregu.1998.274.5.r1473.
Full textAbstract:
In male urethan-anesthetized rats, activity was measured in nerves that run over the proximal urethra. The urethral nerve response to stepwise urethral perfusion could be described by a four-parameter model (fit error <6%). At the onset of perfusion, the urethra was closed and the pressure increased with the infused volume. The nerve activity (NA) increased linearly with this inserted volume to a maximum (NAmax), which was proportional to the instantaneous pressure. The duration of this first episode (δ t) was inversely proportional to the perfusion rate. After infusion of a fixed volume, the urethra opened and the NA decreased with a time constant ϕ−1 (∼1.8 s) to an elevated level (NAlevel). NAlevel was linearly related to the steady-state pressure. Accordingly, sensors in the urethra are sensitive to pressure rather than to the perfusion rate. The parameters NAmax, NAlevel, and δ t showed very good reproducibility (SD ∼19% of mean). The measured activity was most likely afferent and conducted to the major pelvic ganglion.
7
Pham, Jonathan, Ricky R. Savjani, Yu Gao, Minsong Cao, Peng Hu, Ke Sheng, Daniel A. Low, Michael Steinberg, Amar U. Kishan, and Yingli Yang. "Evaluation of T2-Weighted MRI for Visualization and Sparing of Urethra with MR-Guided Radiation Therapy (MRgRT) On-Board MRI." Cancers 13, no. 14 (July 16, 2021): 3564. http://dx.doi.org/10.3390/cancers13143564.
Full textAbstract:
Purpose: To evaluate urethral contours from two optimized urethral MRI sequences with an MR-guided radiotherapy system (MRgRT). Methods: Eleven prostate cancer patients were scanned on a MRgRT system using optimized urethral 3D HASTE and 3D TSE. A resident radiation oncologist contoured the prostatic urethra on the patients’ planning CT, diagnostic 3T T2w MRI, and both urethral MRIs. An attending radiation oncologist reviewed/edited the resident’s contours and additionally contoured the prostatic urethra on the clinical planning MRgRT MRI (bSSFP). For each image, the resident radiation oncologist, attending radiation oncologist, and a senior medical physicist qualitatively scored the prostatic urethra visibility. Using MRgRT 3D HASTE-based contouring workflow as baseline, prostatic urethra contours drawn on CT, diagnostic MRI, clinical bSSFP and 3D TSE were evaluated relative to the contour on 3D HASTE using 95th percentile Hausdorff distance (HD95), mean-distance-to-agreement (MDA), and DICE coefficient. Additionally, prostatic urethra contrast-to-noise-ratios (CNR) were calculated for all images. Results: For two out of three observers, the urethra visibility score for 3D HASTE was significantly higher than CT, and clinical bSSFP, but was not significantly different from diagnostic MRI. The mean HD95/MDA/DICE values were 11.35 ± 3.55 mm/5.77 ± 2.69 mm/0.07 ± 0.08 for CT, 7.62 ± 2.75 mm/3.83 ± 1.47 mm/0.12 ± 0.10 for CT + diagnostic MRI, 5.49 ± 2.32 mm/2.18 ± 1.19 mm/0.35 ± 0.19 for 3D TSE, and 6.34 ± 2.89 mm/2.65 ± 1.31 mm/0.21 ± 0.12 for clinical bSSFP. The CNR for 3D HASTE was significantly higher than CT, diagnostic MRI, and clinical bSSFP, but was not significantly different from 3D TSE. Conclusion: The urethra’s visibility scores showed optimized urethral MRgRT 3D HASTE was superior to the other tested methodologies. The prostatic urethra contours demonstrated significant variability from different imaging and workflows. Urethra contouring uncertainty introduced by cross-modality registration and sub-optimal imaging contrast may lead to significant treatment degradation when urethral sparing is implemented to minimize genitourinary toxicity.
8
Ruiz, Sonia, Miguel Virseda-Chamorro, Fabian Queissert, Andrés López, Ignacio Arance, and Javier C. Angulo. "The Mode of Action of Adjustable Transobturator Male System (ATOMS): Intraoperative Urethral Pressure Measurements." Uro 1, no. 2 (June 8, 2021): 45–53. http://dx.doi.org/10.3390/uro1020007.
Full textAbstract:
(1) Background: The Adjustable Transobturator Male System (ATOMS) device is increasingly used to treat post-prostatectomy incontinence as it enhances residual urinary sphincteric function and allows continence recovery or improvement by dorsal compression of the bulbar urethra through a fixed transobturator mesh passage. The mode of action and the profile of the patients with best results are not totally understood. (2) Methods: Intraoperative urethral pressure measurements at different filling levels of the ATOMS device show increased urethral resistance and enhanced residual sphincteric activity. We evaluated whether the pattern of urethral pressure change secondary to serial progressive intraoperative filling of the cushion can predict postoperative results after ATOMS placement. (3) Results: The regression analysis showed a significant direct relationship between cushion volume and intraurethral pressure (p = 0.000). The median intraurethral pressure at atmospheric pressure was 51 ± 22.7 cm H2O, and at atmospheric pressure plus 4 mL was 80 ± 23.1 cm H2O). Cluster analyses defined a group of patients (n = 6) formed by patients with a distensible urethra and 100% continence after adjustment in contrast to another group (n = 3) with rigid urethras and 33% continence after adjustment. (4) Conclusions: As a part of its continence mechanism, the ATOMS device leads to continence by increasing intraurethral pressure owing to the stretching effect on the urethral wall caused by cushion filling that increases urethral resistance.
9
Krukowski, Jakub, Adam Kałużny, Jakub Kłącz, and Marcin Matuszewski. "Comparison between cystourethrography and sonourethrography in preoperative diagnostic management of patients with anterior urethral strictures." Medical Ultrasonography 20, no. 4 (December 8, 2018): 436. http://dx.doi.org/10.11152/mu-1613.
Full textAbstract:
Aim: To evaluate the urethral lesions and the degree of spongiofibrosis using cystourethrography (CUG) and sonourethrography (SUG) in order to propose the best imaging method for further surgical treatment.Material and methods: The study involved 66 patients with anterior urethral strictures with indication for urethroplasty. Results of CUG and SUG were compared with each other and data from surgical protocol.Results: Totally 72 strictures were detected; 47 in the bulbar part of urethra and 25 in the penile urethra. The mean length of the stenosis was 16.43 mm for CUG and 27.41 mm for SUG and 31.05 mm during surgery. The correlation levels between imaging techniques and intraoperative measurements were 0.55 (p<0.001) for CUG and 0.73 (p<0.001) for SUG. After dividing the strictures according to their location, better correlation for stenoses was obtained in penile urethra: 0.66 (p<0.001) for CUG and 0.86 (p<0.001) for SUG.Conclusions: SUG seems to be a simple and fast examination to evaluate urethral strictures. It is more accurate in comparison to CUG and gives a possibility to assess the spongiofibrosis. This information suggests that SUG can be a good complement to CUG in diagnosis of anterior urethtral strictures.
10
Vasconcelos, Kath Freire de, Raquel Guedes Ximenes, Francisco Sávio de Moura Martins, Aline De Sousa Alves, Sabrina Barros Araújo, Jéssica Kária de Andrade, José Rômulo Soares dos Santos, and Pedro Isidro da Nóbrega Neto. "Assessment of the Bilateral Block of the Trunk of the Pudendal Nerve in Cats with Urethral Obstruction." Acta Scientiae Veterinariae 46, no. 1 (May 16, 2018): 7. http://dx.doi.org/10.22456/1679-9216.81802.
Full textAbstract:
Background: Clinical care of cats with urethral obstruction is a common routine in feline clinical medicine and the re-establishment of urinary flow is essential for long-lasting correction of the pathophysiological alterations presented. For this chemical restraint is usually employed, that together with the alteration, increases the anesthetic risk of these patients. Improvement in anesthetic techniques, especially the loco-regional, may contribute to reducing the anesthetic risk of these patients and facilitate maneuvers to clear the obstruction. Thus the objective of the present study was to describe and assess the bilateral block technique of the pudendal nerve in 16 cats with urethral obstruction.Materials, Methods & Results: Sixteen male crossbred cats were used, with partial or total urethral obstruction, attended at the Veterinary Hospital of the Federal University of Campina Grande, PB, Brazil. The anesthetic block of the pudendal nerve trunk was carried out by placing the local anesthetic close to the ventral foramen of the second sacral vertebra, using a 13 x 0.45 mm needle attached to a 1 mL syringe. To assess the effectiveness of the bilateral block, the analgesia promoted was assessed using the substitute (“Reaction to Palpating the Surgical Wound” of subscale 1 (pain expression) of the “Compound Multi-dimensional Scale to Assess Post Operational Pain in Cats”. This assessment was made before the bilateral block (M0) and 10 min afterwards (M1) and the scores ranged from 0 to 3. In addition, a segmental assessment of the urethra was made, where, by passing a probe the sensitivity was assessed of the urethral ostium, penile and pelvic urethra and the relaxing of the external urethral sphincter. This assessment was made at M1 and classified as present or absent. In the cases where the bilateral block was inefficient, the technique was repeated, in the same locations and at the same dose as initially administered, and a new assessment (M2) was made 10 minutes after the second administration. In 12 of the 16 patients assessed the bilateral block was made once. The following were observed in these patients at M1: reduction in the reaction to penile manipulation (P = 0.003), total relaxation of the external urethral sphincter and absence of sensitivity to passing the probe through the penile urethra (P = 0.000) and insensitivity of the ostium urethrae (P = 0.006). In the animals in which the anesthetic bilateral block was repeated (4/16) the value of p adjusted for penile manipulation was 0.05. There was no reaction to the probe passage through the ostium urethrae and the penile urethra or contraction of the external urethral sphincter in 3 of the 4 animals (P = 0.625). Considering the total number of animals assessed, the urethral obstruction of the pudendal nerve trunk, carried out one or twice, caused statistically significant (P = 0.004) insensitivity to penile manipulation, probing of the ostium urethrae and the penile urethra and total relaxation of the external urethral sphincter in 14 of the 16 animals. In three patients concomitant anesthetic bilateral block was observed of the sciatic nerve, bilateral (two animals) or unilateral (one animal).Discussion: studies on the feline pudendal nerve have demonstrated that the sensitive and motor bilateral block of this nerve is possible, as corroborated by the present study. Although an atomic study had shown the possibility of concomitant bilateral block of the sciatic nerve, and therefore, according to the authors, the technique should not be recommended, this finding did not demonstrate great clinical relevance, because in most cases the patients remained under fluid therapy throughout the anesthetic recovery period (about two hours) and therefore with restricted movement. Nevertheless, studies should be carried out to improve this technique.
11
Chen, Defang, Wen Meng, Ling Shu, Shuang Liu, Yongzhong Gu, Xiaoyan Wang, and Mei Feng. "ANO1 in urethral SMCs contributes to sex differences in urethral spontaneous tone." American Journal of Physiology-Renal Physiology 319, no. 3 (September 1, 2020): F394—F402. http://dx.doi.org/10.1152/ajprenal.00174.2020.
Full textAbstract:
Stress urinary incontinence (SUI) is more common in women than in men, and sex differences in anatomic structure and physiology have been suggested as causes; however, the underlying cellular and molecular mechanisms remain unclear. The spontaneous tone (STT) of the urethra has been shown to have a fundamental effect on preventing the occurrence of SUI. Here, we investigated whether the urethral STT exhibited sex differences. First, we isolated urethral smooth muscle (USM) and detected STT in female mice and women. No STT was found in male mice or men. Furthermore, caffeine induced increased contractility and intracellular Ca2+ concentration in urethrae from female mice compared with male mice. EACT [an N-aroylaminothiazole, anoctamin-1 (ANO1) activator] elicited increased intracellular Ca2+ concentration and stronger currents in female mice than in male mice. Moreover, ANO1 expression in single USM cells from women and female mice was almost twofold higher than that found in cells from men and male mice. In summary, ANO1 in USM contributes to sex differences in urethral spontaneous tone. This finding may provide new guidance for the treatment of SUI in women and men.
12
Julia-Guilloteau, V., P. Denys, J. Bernabé, K. Mevel, E. Chartier-Kastler, L. Alexandre, and F. Giuliano. "Urethral closure mechanisms during sneezing-induced stress in anesthetized female cats." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 293, no. 3 (September 2007): R1357—R1367. http://dx.doi.org/10.1152/ajpregu.00003.2007.
Full textAbstract:
During stress-induced increase in abdominal pressure, urinary continence is maintained by urethral closure mechanisms. Active urethral response has been studied in dogs and rats. Such an active urethral response is also believed to occur in humans during stress events. We aimed to investigate urethral closure mechanisms during sneezing in cats. Urethral pressures along the urethra (UP1–UP4), with microtip transducer catheters with UP4 positioned in the distal urethra where the external urethral sphincter (EUS) is located, and intravesical pressure were measured, and abdominal wall, anal sphincter (AS), levator ani (LA), and EUS electromyograms (EMGs) were recorded during sneezing under closed-abdomen and open-abdomen conditions in eight anesthetized adult female cats. Proximal and middle urethral response induced by sneezing was not different from bladder response. Distal urethral response was greater compared with proximal and middle urethral and bladder response. In the open-abdomen bladder, proximal and middle urethral responses were similarly decreased and distal urethral response was unchanged compared with the closed-abdomen bladder. Bladder and urethral responses were positively correlated to sneeze strength. EUS, LA, and AS EMGs increased during sneezing. No urine leakage was observed, regardless of the strength of sneeze. In cats urethral closure mechanisms are partly passive in the proximal and middle urethra and involve an active component in the distal urethra that is believed to result from EUS and possibly LA contractions. Because central serotonin exerts similar effects on the lower urinary tract in cats and humans, the cat may represent a relevant model for pharmacological studies on continence mechanisms.
13
Spilotros, Marco, Suzie Venn, Paul Anderson, and Tamsin Greenwell. "Penile urethral stricture disease." Journal of Clinical Urology 12, no. 2 (June 22, 2018): 145–57. http://dx.doi.org/10.1177/2051415818774227.
Full textAbstract:
Patients affected by a urethral stricture account for a considerable cost to all healthcare systems. The estimated prevalence of all urethral stricture in the UK is 10/100,000 men during youth, increasing to about 40/100,000 by age 65 years and to more than 100/100,000 thereafter. A penile urethral stricture is a narrowing of the lumen of the urethra due to ischaemic fibrosis of the urethral epithelium and/or spongiofibrosis of the corpus spongiosum occurring within the penile urethra. Its aetiology is largely idiopathic but other important causes are failed hypospadias repair and lichen sclerosus, which account for 60% of all cases. Strictures of the anterior urethra account for 92% of cases: bulbar strictures are more frequent (46.9%), followed by penile (30.5%) and combined bulbar/penile (9.9%), that is, 40.4% of all men presenting with stricture will have a penile urethral stricture alone or in combination with a bulbar urethral stricture. There are several options for the treatment of penile urethral strictures ranging from less invasive treatments, including urethral dilatation and direct vision internal urethrotomy, to more complex augmentation graft and flap urethroplasty. The aim of the present review is to describe the aetiology and epidemiology of anterior urethral strictures and the available options reported in literature for their treatment. Level of evidence: 1a
14
Gozar, H., Ra Prișcă, and Zoltán Derzsi. "Two Cases of Dorsal Urethral Duplication." Acta Medica Marisiensis 59, no. 1 (February 1, 2013): 52–54. http://dx.doi.org/10.2478/amma-2013-0012.
Full textAbstract:
Abstract Urethral duplication is a rare congenital anomaly. In addition to a normally urethra, there is an accessory urethra arising from the bladder or the proximal urethra which may open anywhere on the penis or even on the perineum. Many patients with this malformation are asymptomatic. Some patients may complain of intermittent discharge from the accessory urethra, incontinence, infection, double streams or stricture. The duplicated urethra may be complete or incomplete, may be located dorsal, ventral or in Y-type. The treatment of urethral duplication is individualized, depending on the type of malformation. We report two cases of dorsal urethral duplication discovered in two boys.
15
Gustafson, Paul, Howard N. Fenster, and Alan I. So. "Urethral squamous cell papilloma: Case report and review of literature." Canadian Urological Association Journal 8, no. 5-6 (May 21, 2014): 364. http://dx.doi.org/10.5489/cuaj.1582.
Full textAbstract:
Lesions around the urethral meatus in women are common. The differential diagnosis for these lesions is extensive and includes urethral caruncle, urethral prolapse, urethral diverticulum, periurethral gland abscesses and, of most concern, urethral carcinoma. Non-invasive squamous lesions of the urethra are rare and their clinical significance is uncertain. We present a case of a urethral squamous papilloma at the urethral meatus in a premenopausal woman causing significant symptoms.
16
Hasan, Zaheer, Bindey Kumar, and Prem Kumar. "Congenital Posterior Urethral Diverticulum in a Male Child Case Report." Journal of Nepal Paediatric Society 32, no. 3 (February 24, 2013): 257–58. http://dx.doi.org/10.3126/jnps.v32i3.5914.
Full textAbstract:
Bladder neck and posterior urethra are common sites for obstructive uropathy in children. Diverticula of posterior urethra are rare cause of obstruction in children. A six year old boy presented with features of bladder outflow obstruction since birth. Ultrasound findings were suggestive of posterior urethral valve. Micturating cystourethrogram and endoscopic examinations revealed posterior urethral diverticulum which was placed dorsally. Diverticulectomy and reconstruction of urethra was performed by midline perineal incision. This report emphasizes that a posterior urethral diverticulum may be considered in those cases where features are suggestive of posterior urethral valve bladder outflow obstruction. DOI: http://dx.doi.org/10.3126/jnps.v32i3.5914 J. Nepal Paediatr. SocVol.32(3) 2012 257-258
17
Melonakos, Emmanuel J., and Richard A. Santucci. "Treatment of Low-Grade Bulbar Transitional Cell Carcinoma with Urethral Instillation of Mitomycin C." Advances in Urology 2008 (2008): 1–2. http://dx.doi.org/10.1155/2008/173694.
Full textAbstract:
A 63-year old man was referred to us after three rapid recurrences of low-grade urethral papillary transitional cell carcinoma of the bulbar urethra, after repeated primary excision. Cystoscopy confirmed 3-4 low-grade urethral transitional cell carcinomas, which were subsequently fulgurated. After urethral healing, a solution of Mitomycin C (40 mg/80 cc) was instilled into the urethra for fifteen minutes and held in place with a penile clamp. Urethral instillations were repeated weekly for six weeks. The patient is currently disease-free more than one year and three months posttreatment. This case highlights the successful treatment of urethral carcinoma with topical chemotherapy, which is usually reserved for the bladder, using a slight modification of standard technique.
18
Jankowski, Ron J., Rachelle L. Prantil, Michael B. Chancellor, William C. de Groat, Johnny Huard, and David A. Vorp. "Biomechanical characterization of the urethral musculature." American Journal of Physiology-Renal Physiology 290, no. 5 (May 2006): F1127—F1134. http://dx.doi.org/10.1152/ajprenal.00330.2005.
Full textAbstract:
Rigorous study of the associations between urethral structural anatomy and biomechanical function is necessary to advance the understanding of the development, progression, and treatment of urethral pathologies. An ex vivo model was utilized to define the relative biomechanical contributions of the active (muscle) elements of the female urethra relative to its passive (noncontractile) elements. Whole urethras from female, adult rats were tested under a range of applied intraluminal pressures (0 to 20 mmHg) as a laser micrometer simultaneously measured midurethral outer diameter. Active tissue characterization was performed during induced contraction of either smooth muscle alone ( Nω-nitro-l-arginine, phenylephrine), striated muscle alone (sodium nitroprusside, atropine, hexamethonium, acetylcholine), or during collective activation of both muscles ( Nω-nitro-l-arginine, phenylephrine, acetylcholine). The subsequent collection of paired passive biomechanical responses permitted the determination of parameters related to intrinsic muscle contractile function. Activation of each muscle layer significantly influenced the biomechanical responses of the tissue. Measures of muscle responsiveness over a wide range of sustained opposing pressures indicated that an activated striated muscle component was approximately one-third as effective as activated smooth muscle in resisting tissue deformation. The maximum circumferential stress generated by the striated muscle component under these conditions was also determined to be approximately one-third of that generated by the smooth muscle (748 ± 379 vs. 2,229 ± 409 N/m2). The experiments quantitatively reveal the relative influence of the intrinsic urethral smooth and striated muscle layers with regard to their effect on the mechanical properties and maximum functional responses of the urethra to applied intralumenal stresses in the complete absence of extrinsic influences.
19
Alnadhari, Ibrahim, Osama Abdelhaleem Abdeljaleel, Venkata Ramana Pai Sampige, Ausama Abdulmuhsin, and Ahmad Shamsodini. "Penile Fracture: Simultaneous Complete Urethral Rupture with Bilateral Corpora Cavernosa Rupture." Case Reports in Urology 2018 (September 25, 2018): 1–3. http://dx.doi.org/10.1155/2018/4929518.
Full textAbstract:
Penile fracture is not uncommon blunt trauma to the penis. Here, we present a rare case of penile fracture during sexual intercourse. The patient presented with penile swelling, bleeding per urethra, and inability to pass urine. Retrograde urethrogram showed significant extravasation of contrast from anterior penile urethra and no contrast passing to proximal urethra. Surgical exploration showed complete urethral rupture and bilateral cavernosal rupture. This case represents the value of urethrogram to evaluate the urethral injury and the association of complete urethral injury with bilateral ventral cavernosal injury.
20
Gelman, Joel, and Eric S. Wisenbaugh. "Posterior Urethral Strictures." Advances in Urology 2015 (2015): 1–11. http://dx.doi.org/10.1155/2015/628107.
Full textAbstract:
Pelvic fracture urethral injuries are typically partial and more often complete disruptions of the most proximal bulbar and distal membranous urethra. Emergency management includes suprapubic tube placement. Subsequent primary realignment to place a urethral catheter remains a controversial topic, but what is not controversial is that when there is the development of a stricture (which is usually obliterative with a distraction defect) after suprapubic tube placement or urethral catheter removal, the standard of care is delayed urethral reconstruction with excision and primary anastomosis. This paper reviews the management of patients who suffer pelvic fracture urethral injuries and the techniques of preoperative urethral imaging and subsequent posterior urethroplasty.
21
Tiwari, Kabir, Amit Mani Upadhaya, Ashok Kunwar, and Sanjesh Bhakta Shrestha. "Urethral Strictures and its Management at Tertiary Hospital of Nepal." Journal of Nepal Health Research Council 18, no. 2 (September 8, 2020): 310–12. http://dx.doi.org/10.33314/jnhrc.v18i2.2503.
Full textAbstract:
Background: Urethral stricture can occur from urethral meatus to bladder neck. Treatment of urethral stricture include dilatation, endoscopic incision and anastomotic urethroplasty. The aim of this study is to report our experience in the management of different types of urethral strictures.Methods: We retrospectively reviewed the chart of all the patients of urethral stricture who received treatment at Kathmandu model hospital between January 2015 and October 2019. Different types of urethral stricture along with various modalities of treatment given were recorded.Results: Fifty patients were included in this study, all were males. Mean age was 49 (16-82) years. Bulbar urethra was the most common site in 54% of cases and bulbomembranous least common, only 10% of cases. Depending on sites and size of stricture, different types of surgery performed were meatoplasty, dviu and anastomotic urethroplasty.Conclusions: Urethral stricture is a troublesome disease and can occur anywhere from meatus to the bladder neck. Different surgical techniques are present and the treatment should be individualized, depending on location and length of the stricture.Keywords: Urethra; urethral stricture; urethroplasty
22
Davidson, Joseph, Naomi Wright, and Massimo Garriboli. "Urethral Duplication with Two Hypospadic Meati—An Unusual Variant." European Journal of Pediatric Surgery Reports 04, no. 01 (November 8, 2016): 037–40. http://dx.doi.org/10.1055/s-0036-1588015.
Full textAbstract:
AbstractDuplication of the urethra is a rare congenital anomaly, with approximately 300 cases reported in the literature. We report a unique case of this condition in a male infant. This case differs from the classical Effman type II-A2 duplication because of the presence of two hypospadic urethral meati, as opposed to a ventral or dorsal accessory meatus with a normally positioned distal urethra. The patient underwent a single-stage repair consisting of a proximal urethra-urethral anastomosis and distal urethral tubularization at 21 months of age with excellent results in terms of both function and cosmesis.
23
Prasad Ray, Rajendra, Bastab Ghosh, and Dilip Kumar Pal. "Urethral foreign body in an adolescent boy: report of two rare cases and review of literature." International Journal of Adolescent Medicine and Health 27, no. 4 (November 1, 2015): 463–65. http://dx.doi.org/10.1515/ijamh-2014-0057.
Full textAbstract:
Abstract The presence of a foreign body in the urethra is uncommon. A wide variety of foreign bodies have been described in urethras, but they are often missed in physical examinations as the patient tries to hide the fact. We report two unusual cases of foreign bodies in the urethra in two adolescent boys suffering from psychiatric disorders. In the first case, a 12-year-old boy presented with introduction of sewing needle into the urethra 3 days back. The patient in that case suffered from a delusional disorder. In the second case, a 19 year old man introduced a metallic screw into his urethra for sexual gratification several times in the preceding 4 years. That patient suffered from schizophrenia. Although psychiatric illness is associated with urethral foreign body, such underlying psychiatric disorders are very rare.
24
Alam, Jahangir, and Rumi Farhad Ara. "Surgical Management and Post-Operative Outcomes of Urinary Outflow Obstruction: Experience of 50 Cases in Bangladesh." Journal of National Institute of Neurosciences Bangladesh 3, no. 2 (May 26, 2018): 84–88. http://dx.doi.org/10.3329/jninb.v3i2.36770.
Full textAbstract:
Background: Management of urinary outflow obstruction is very crucial.Objective: The purpose of the present study was to see the different management of urinary outflow obstruction with their post-operative outcomes.Methodology: This non-randomized clinical trial was conducted in the Department of Surgery at Rajshahi Medical College, Rajshahi, Bangladesh from September 1994 to December 1995 for a period of one year and three months. All the patients who were presented with bladder outflow obstruction and were admitted in the general surgical unit of the hospital were taken as study population. These patients were surgically managed in different procedures. The follow up was done to record the post-operative surgical outcomes.Result: A total number of 50 patients were recruited for this study. Benign enlargement of prostate was found in 13 cases of which 11(22.0%) cases were managed by suprapubic transvesical prostatectomy. Impacted urethral stone was found in 13 cases of which 4(8.0%) cases were managed by urethro-lithotomy followed by repair of urethra and indwelling catheter. Stricture urethra was found in 11 cases and all cases (100.0%) cases were managed by intermittent dilatation under general anesthesia. In 7 cases of rupture urethra, initially all patients were managed by suprabpublic cystostomy which was 7(14.0%) cases in number. All the 3 cases of carcinoma prostate were managed by prostatectomy and radiotherapy plus hormone therapy. A total number of 16 patients were managed by prostatectomy of which 1(2.0%) case was developed immediate postoperative hemorrhage which was managed by blood transfusion and continuous irrigation with normal saline. One patient developed postoperative clot retention due to blockage of Foley’s catheter, two patients developed postoperative incontinence, immediately after removal of the catheter. Out of 11 patients of impacted urethral stone, one developed urethral fistula and one developed UTI. Recurrent stricture urethra occurred in 3 patients. Seven patients with rupture urethra, 3 developed stricture urethra and 3 developed stricture urethra.Conclusion: In conclusion different surgical procedure are employed during the management of urinary outflow obstruction and immediate postoperative hemorrhage, postoperative clot retention, postoperative incontinence, urethral fistula, UTI and recurrent stricture urethra are the most common complication after surgical management of urinary outflow obstruction patients.Journal of National Institute of Neurosciences Bangladesh, 2017;3(2): 84-88
25
Vorobev, V. A., and V. A. Beloborodov. "MODERN METHODS OF TREATING DISEASES OF THE BULBO-MEMBRANOUS PART OF URETHRA." Acta Biomedica Scientifica 3, no. 5 (October 29, 2018): 116–25. http://dx.doi.org/10.29413/abs.2018-3.5.17.
Full textAbstract:
Strictures of the bulbous-membranous urethra are a common cause of obstructive urination disorder. Modern trends in the development of medicine lead to a wider application of endoscopic method, a more frequent cause of iatrogenic injury of the urethra. At present, conservative, endourologic and reconstructive methods of care are used to treat urethral strictures. There are several conservative, endourological and reconstructive methods for treating patients with urethral stricture. Conservative methods include interventions that do not involve the destruction of urethral stricture or its reconstruction, such as stenting, blind dilatation, and recanalization of the urethra. Performing blind dilatation strictures of the bulbo-membranous urethra is not recommended because of the high risk of false path formation and low efficiency. Endourological operations refer to surgical methods of care and suggest the natural restoration of urethral tissues after the destruction of stricture. Because of the low effectiveness of correction of strictures of the posterior urethra (more than 90 % of relapses in five years), this method is a variant of temporary or palliative care. Currently, two approaches to the reconstruction of the bulbo-membranous urethra are used: anastomotic and replacement operations. Anastomotic surgery involves excision of the affected area and juxtaposition of healthy urethral tissues without tension. Replacement plastic allows to restore patency of the urethra by increasing the diameter of the lumen due to the implantation of various grafts. The article shows that, based on international clinical studies, the most effective method of reconstructing the bulbomembranous urethra is reconstructive surgical methods.
26
Mouafo Tambo, F. F., G. Fossi kamga, C. Kamadjou, L. Mbouche, A. S. Nwaha Makon, J. Birraux, O. G. Andze, F. F. Angwafo, and P. Y. Mure. "Challenges in the Diagnosis and Management of Acquired Nontraumatic Urethral Strictures in Boys in Yaoundé, Cameroon." Case Reports in Urology 2016 (2016): 1–4. http://dx.doi.org/10.1155/2016/2586458.
Full textAbstract:
Introduction. Urethral strictures in boys denote narrowing of the urethra which can be congenital or acquired. In case of acquired strictures, the etiology is iatrogenic or traumatic and rarely infectious or inflammatory. The aim of this study was to highlight the diagnostic and therapeutic difficulties of acquired nontraumatic urethral strictures in boys in Yaoundé, Cameroon.Methodology. The authors report five cases of nontraumatic urethral strictures managed at the Pediatric Surgery Department of the YGOPH over a two-year period (November 2012–November 2014). In order to confirm the diagnosis of urethral stricture, all patients were assessed with both cystourethrography and urethrocystoscopy.Results. In all the cases the urethra was inflammatory with either a single or multiple strictures. The surgical management included internal urethrotomy (n=1), urethral dilatation (n=1), vesicostomy (n=2), and urethral catheterization (n=3). With a median follow-up of 8.2 months (4–16 months) all patients remained symptoms-free.Conclusion. The authors report the difficulties encountered in the diagnosis and management of nontraumatic urethral strictures in boys at a tertiary hospital in Yaoundé, Cameroon. The existence of an inflammatory etiology of urethral strictures in boys deserves to be considered.
27
Koju, Pratigya, Bijendra Shah, and Dr Raj Kishor Shah. "Efficacy of Uttar Basti in Urethral Stricture – A Review." Healer 1, no. 1 (September 17, 2020): 32–35. http://dx.doi.org/10.51649/healer.5.
Full textAbstract:
Introduction: Narrowing of lumen of urethra is known as urethral stricture.70% of uretral stricture is inscidious at bulb. Trauma,infections like( TB,Gonorrhoea), TURP are the main causes of urethral stricture. Symptoms include varying amt of urethral dischargeæ morning dew drop”,difficulty in micturation,dribbling of urine, increased frequency,incomplete voiding of urine etc. According to modern literature, urethroplasty and dilatation of urethra are the treatment procedures followed for urethral stricture. In Ayurveda urethral stricture can be correlated with mutra marga samkocha. According to Sushruta Samhita uttarbasti is one of the effective procedure for mutra marga samkocha. Material and methods: This paper provides a collective information regarding Mutra Marga Samkocha( Urethral Stricture), from Nighantu, Samhita and Modern Medicine.Uttarbasti is performed by the use of oils like Bala taila,Tila taila,Apamarga kshar taila etc. Result and Discussion: Most of the concerned informations are retrieved from published international journals and classical text of Ayurveda. As per published research papers uttarbasti is highly effective in case of urethral stricture. Conclusion:
28
Hokanson, James A., Christopher L. Langdale, Arun Sridhar, and Warren M. Grill. "OAB without an overactive bladder in the acute prostaglandin E2 rat model." American Journal of Physiology-Renal Physiology 313, no. 5 (November 1, 2017): F1169—F1177. http://dx.doi.org/10.1152/ajprenal.00270.2017.
Full textAbstract:
Intravesical prostaglandin E2 (PGE2) was previously used to induce overactive bladder (OAB) symptoms, as it reduces bladder capacity in rats and causes a “strong urgency sensation” in healthy women. However, the mechanism by which this occurs is unclear. To clarify how PGE2 reduces bladder capacity, 100 µM PGE2 was administered intravesically during open, single-fill cystometry with simultaneous measurement of sphincter EMG in the urethane-anesthetized female Wistar rat. PGE2 was also applied to the urethra or bladder selectively by use of a ligature at the bladder neck before (urethra) or during (bladder) closed-outlet, single-fill cystometry. Additional tests of urethral perfusion with PGE2 were made. PGE2 decreased bladder capacity, increased voiding efficiency, and increased sphincter EMG during open cystometry compared with saline controls. The number of nonvoiding contractions did not change with PGE2; however, bladder compliance decreased. During closed-outlet cystometry, PGE2 applied only to the bladder or the urethra did not decrease bladder capacity. Urethral infusion of PGE2 decreased urethral perfusion pressure. Taken together, these results suggest that intravesical PGE2 may decrease bladder capacity by targeting afferents in the proximal urethra. This may occur through urethral relaxation and decreased bladder compliance, both of which may increase activation of proximal urethra afferents from distension of the proximal urethra. This hypothesis stands in contrast to many hypotheses of urgency that focus on bladder dysfunction as the primary cause of OAB symptoms. Targeting the urethra, particularly urethral smooth muscle, may be a promising avenue for the design of drugs and devices to treat OAB.
29
Sankalp, Dwivedi, S. R. Joharapurkar, and Deshmukh Abhay. "Double breasting repair of urethral fistula in a patient with perineal abscess secondary to a large urethral stone." Indian Journal of Plastic Surgery 41, no. 02 (July 2008): 226–28. http://dx.doi.org/10.1055/s-0039-1699273.
Full textAbstract:
ABSTRACTWe report here a case of urethral fistula managed successfully following incision and drainage for the urethral abscess secondary to a large urethral stone leading to a large diverticulum (another rare condition) by using the technique of double breasting, where we used the redundant urethra and overlying skin
30
Danfulani, M., S. A. Saidu, and M. A. Musa. "Multiple urethral calculus misdiagnosed as urethral stricture: The role of imaging in unknotting the confusion." Asian Journal of Medical Sciences 7, no. 3 (January 6, 2016): 118–20. http://dx.doi.org/10.3126/ajms.v7i3.13874.
Full textAbstract:
Urinary Tract Calculi Impaction / finding in the male urethra is extremely uncommon and can usually be secondary to upper urinary tract calculus formation or primarily arising from the urethra either due to stricture or post-trauma. There is paucity of urethral stricture report in Nigeria, thus this case is reported to highlight the role of imaging in the prompt diagnosis and management of urethral diseases; and to advise urologists to at least always request for imaging modality in their routine evaluation of urethral pathologies. We report a case of a 55 years old male farmer who presented in the Accident and Emergency Unit of our facility with signs and symptoms of acute urinary retention. A working diagnosis of urethral stricture was entertained and prompt diagnosis was made on image. Existing literatures outlining the pathologies, clinical presentation, therapeutic consideration and imaging as it relates to urethral calculi were reviewed. We thus concluded that imaging is very vital and fundamental in order to correctly assess any form of urethral pathology.Asian Journal of Medical Sciences Vol. 7(3) 2016 118-120
31
Ranno, S., R. Leonardi, G. Stracuzzi, G. Minaldi, and P. Miria. "Strictures and fistulas of the anterior urethra." Urologia Journal 64, no. 4 (August 1997): 400–404. http://dx.doi.org/10.1177/039156039706400405.
Full textAbstract:
– The first documents of urethral surgery for urethral strictures date back to the 4th century BC. In the past, endoscopic surgery was the best solution for most urologists. Nowadays, literature shows that the approach to urethral strictures depends on the degree of involvement of the spongy body. The choice of surgical reconstruction technique depends on the anatomical differences in the anterior portion of the urethra, which is divided anatomically into navicular, penile and bulbar. The gold standard for urethroplasty of the navicular urethra is the free graft which can take root due to the presence of glandular tissue. Techniques using a preputial pedunculated graft are good for penile urethra, while a free graft of preputial origin, that has first been perforated and then tubularised, is suggested for very long strictures (> 5 cm). Epidermal or mucosal free grafts can be used for bulbous urethral strictures, due to the presence of thick spongy tissue. The urethra should be completely substituted with a neo-urethra formed by preputial pedunculated and tubularised graft only for wide strictures with associated fibrosis of the spongy portion. Recurrent strictures can be treated twice with surgery.
32
Chukwubuike, Kevin Emeka, Joseph Tochukwu Enebe, and Obinna Chukwuebuka Nduagubam. "Urethral injury in children: Experience in a teaching hospital in Enugu, Nigeria." Proceedings of Singapore Healthcare 29, no. 3 (June 1, 2020): 151–55. http://dx.doi.org/10.1177/2010105820927423.
Full textAbstract:
Background: Urethral injury in children is uncommon, and its treatment is challenging. This study evaluated our experience in the management of urethral injuries in children who presented at the paediatric surgical unit of a teaching hospital in Enugu, Nigeria. Methods: The medical records of patients younger than 15 years old admitted to our centre with urethral injury from January 2008 and December 2017 were reviewed retrospectively. Results: During the period of the study, 11 cases (all male) were managed. The mean age of the patients at presentation was 11 years. Road traffic accident was the most common mechanism of injury, and the bulbar urethra was the most injured part of the urethra. All the patients had urethroplasty through the perineal approach. There was 90% success at first instance. One patient required redo urethroplasty. Conclusion: Urethral trauma is associated with considerable morbidity. Road traffic accident was the most common mechanism of injury, and the bulbar urethra was the part of the urethra most affected. Transperineal urethroplasty was an effective modality of treatment.
33
Souza, Ana Beatriz Gomes de, Haylton Jorge Suaid, Carla Adelino Suaid, Silvio Tucci Jr, Adauto José Cologna, and Antonio Carlos Pereira Martins. "Comparison of two experimental models of urodynamic evaluation in female rats." Acta Cirurgica Brasileira 23, suppl 1 (2008): 59–65. http://dx.doi.org/10.1590/s0102-86502008000700011.
Full textAbstract:
PURPOSE: Urodynamic studies in small animals can be performed through urethral sounding or cystostomy. OBJECTIVE: To compare the two methods of urodynamic evaluation in female rats. METHODS: Ten female rats weighing on average 250g, under anesthesia with urethane (1,25 mg/kg) were submitted in three repeats to an urethal catheter of 0,64 mm in external diameter for cystometric measurements of vesicle pressure(VP1) and contraction time (CT1). The catheter was extracted at a constant velocity of 0.05 cm/minute until complete exteriorization and determinations of maximal urethral pressure (UP1) and functional urethral length (FUL1). This was followed by a cystostomy with catheter PE50 and a new determination of the vesical pressure (VP2). After bladder denervation, a new cystometric record indirectly infered the maximum urethral closure pressure (UP2). The peak urethal pressure (UP3) and the functional urethral length (FUL2) were determined in another urethral sounding. The pressure registration system consisted of a continuous infusion pump regulated to a flow of 0.1 ml/minute connected both to the cystostomy catheter (PE-50) or the urethal catheter (0.64mm) and the polygraph Narco-Biosystem. Statistical analysis employed the Wilcoxon non-parametric test RESULTS: Mean VP1= 48,2 mmHg (11,8 SD); Mean VP2 = 38,2 mmHg (9,0 SD) "p" (VP1 X VP2) = 0,0039. Mean CT1=30,2 s (21,5 SD); Mean CT2=20,0 s(7 SD) p (CT1 X CT2) = 1,28. Mean UP1 = 47,2 mmHg (6,5 SD); Mean UP2 = 21,3 mmHg (6,6 SD), mean UP3 = 40,7 mmHg(13,3 SD) p (UP1 X UP2) = 0,002; "p" (UP1 X UP3) = 0,084; p (UP2 X UP3) = 0,002. Mean FUL1=14,2 mm (1,9 SD); Mean FUL2= 14,1mm (1,9 SD); p (FUL1 X FUL2) = 0,64. CONCLUSIONS: The methods employed to evaluate vesical and urethral pressures are different. The presence of the urethral catheter may be an obstructive factor. Surgical denervation up to the bladder neck level does not compromise urethral function.
34
Sancho, Maria, Angeles García-Pascual, and Domingo Triguero. "Presence of the Ca2+-activated chloride channel anoctamin 1 in the urethra and its role in excitatory neurotransmission." American Journal of Physiology-Renal Physiology 302, no. 3 (February 1, 2012): F390—F400. http://dx.doi.org/10.1152/ajprenal.00344.2011.
Full textAbstract:
We investigated the cellular distribution of the calcium-activated chloride channel (CaCC), anoctamin 1, in the urethra of mice, rats, and sheep by both immunofluorescence and PCR. We studied its role in urethral contractility by examining the effects of chloride-free medium and of several CaCC inhibitors on noradrenergic and cholinergic excitatory responses, and on nitrergic relaxations in urethral preparations. In all species analyzed, CaCC played a key role in urethral contractions, influencing smooth muscle cells activated by increases in intracellular calcium, probably due to calcium influx but with a minor contribution by IP3-mediated calcium release. The participation of CaCC in relaxant responses was negligible. Strong anoctamin 1 immunoreactivity was detected in the smooth muscle cells and urothelia of sheep, rat, and mouse urethra, but not in the interstitial cells of Cajal (ICC) in any of these species. RT-PCR confirmed the expression of anoctamin 1 mRNA in the rat urethra. This anoctamin 1 in urethral smooth muscle probably mediates the activity of chloride in contractile responses in different species, However, the lack of anoctamin 1 in ICCs challenges its proposed role in regulating urethral contractility in a manner similar to that observed in the gut.
35
Agarwal, A., G. Sigdel, and WK Belokar. "A rare case of giant urethral calculus and multiple urethral diverticulum." Journal of College of Medical Sciences-Nepal 8, no. 2 (September 12, 2012): 46–48. http://dx.doi.org/10.3126/jcmsn.v8i2.6838.
Full textAbstract:
Urethral stones in adults are rare and usually encountered with urethral stricture or diverticulum. We report a 54 years old gentleman who presented with urinary retention due to a large urethral calculus impacted in bulbar urethra with multiple stones in anterior and posterior urethral diverticulum. On examination a mass of size 5.5cmx4cmx3cm was palpable at anterior perineum with a fistulous tract from which pus was oozing out. On retrograde urethrogram a large urethral calculus with bulbar diverticulum and multiple radio opacity in prostatic area were revealed. Patient was managed by suprapubic cystostomy initially and later on by external urethrotomy, diverticulectomy, urethroscopic removal of multiple stones in prostatic urethral diverticulum and urethroplasty. Journal of College of Medical Sciences-Nepal,2012,Vol-8,No-2, 46-48 DOI: http://dx.doi.org/10.3126/jcmsn.v8i2.6838
36
Alexandre, Eduardo C., Nailong Cao, Shinsuke Mizoguchi, Tetsuichi Saito, Masahiro Kurobe, Daisuke Gotoh, Meri Okorie, Taro Igarashi, Edson Antunes, and Naoki Yoshimura. "Urethral dysfunction in a rat model of chemically induced prostatic inflammation: potential involvement of the MRP5 pump." American Journal of Physiology-Renal Physiology 318, no. 3 (March 1, 2020): F754—F762. http://dx.doi.org/10.1152/ajprenal.00566.2019.
Full textAbstract:
Prostate inflammation (PI) is a clinical condition associated with infection and/or inflammation of the prostate. It is a common disease frequently associated to lower urinary tract (LUT) symptoms. The urethra is an understudied structure in the LUT and plays a fundamental role in the urinary cycle. Here, we proposed to evaluate the effect of PI on the urethra tissue. Male Sprague-Dawley rats were used, and PI was induced by formalin injection into the ventral lobes of the prostate. The pelvic urethra at the prostatic level was harvested for histological analysis, contraction (electrical field stimulation and phenylephrine), and relaxation (sodium nitroprusside/MK-571) experiments. Various gene targets [cytochrome c oxidase subunit 2, transforming growth factor-β1, interleukin-1β, hypoxia-inducible factor-1α, α1A-adrenoceptor, inositol 1,4,5-trisphosphate receptor type 1, voltage-gated Ca2+ channel subunit-α1D, neuronal nitric oxide synthase, soluble guanylyl cyclase, phosphodiesterase 5A, protein kinase CGMP-dependent 1, and multidrug resistance-associated protein 5 (MRP5; ATP-binding cassette subfamily C member 5)] were quantified, and cGMP levels were measured. No histological changes were detected, and functional assays revealed decreased contraction and increased relaxation of urethras from the PI group. The addition of MK-571 to functional assays increased urethral relaxation. Genes associated with inflammation were upregulated in urethras from the PI group, such as cytochrome oxidase c subunit 2, transforming growth factor-β1, interleukin-1β, and hypoxia-inducible factor-1α. We also found increased expression of L-type Ca2+ channels and the neuronal nitric oxide synthase enzyme and decreased expression of the MRP5 pump. Finally, cGMP production was enhanced in urethral tissue of PI animals. The results indicate that PI is associated with proinflammatory gene expression in the urethra without histologically evident inflammation and that PI produces a dysfunctional urethra and MRP5 pump downregulation, which results in cGMP accumulation inside the cell. These findings would help to better understand LUT dysfunctions associated with PI and the role of MRP pumps in the control of LUT function.
37
Li, Aihua, Wei Fang, Xiaoming Zuo, Feng Zhang, Weiwu Li, Honghai Lu, Sikuan Liu, Hui Wang, and Binghui Zhang. "Transurethral holmium laser vaporization to the urethral tumour through a ureteroscope." Canadian Urological Association Journal 8, no. 11-12 (December 15, 2014): 913. http://dx.doi.org/10.5489/cuaj.2026.
Full textAbstract:
We present 2 cases of urethral cancers: one is recurrent bladder transitional cell carcinoma accompanied by urethral metastatic carcinoma located on the right side of verumontanum, and the other is primary bladder and metastatic urethral adenocarcinoma. The urethral tumour was treated by transurethral holmium laser vaporization to the urethral tumour through a ureteroscope and the bladder tumour was treated with transurethral resection and degeneration of the bladder tumour (TURD-Bt). After the second or third therapy, patients were free of urethral or bladder tumour recurrence; they also did not experience urethral stricture or urinary incontinence during the 24- to 36-month follow-up. Transurethral holmium laser vaporization and TURD-Bt could be performed to treat non-invasive urethral cancer accompanied with bladder cancer and preserve the urethra and bladder.
38
Rudin, Yu E., D. V. Maruhnenko, A. Yu Rudin, D. К. Aliev, G. V. Lagutin, and А. В. Vardak. "Augmentation of the urethral plate in the glans penis area and the distal urethra – effective method of fistula correction in children with hypospadias." Andrology and Genital Surgery 22, no. 1 (April 22, 2021): 62–70. http://dx.doi.org/10.17650/1726-9784-2021-22-1-62-70.
Full textAbstract:
Background. Important causes of complications of hypospadias repair are the deficit of tissues for plastic surgery, grooveless and small size of glans, obliteration of the urethral platewith varying degrees of scarring. The coronal urethral fistula is the most common complication of urethroplasty. Surgeons continue to search for reliable methods of correction of complications.Materials and methods. Between 2011 and 2019, 85 children aged 2 and 17 years presented with coronal fistula of urethra after hypospadias repair. (TIP) Snodgrass – 78 (91.7 %) and Mathiue – 7 (8.2 %) procedures have been performed them earlier. In our clinic previously operated 28 (32 %) boys, primary surgery of the remaining 57 (67 %) was performed in other medical institutions.Results. All patients (85), conditionally, were divided into two groups. The first group included 39 children (45.8 %), with stitching a fistula, the second group consisted of 46 patients (54.1 %), with augmentation of the urethral plate of the glans and distal urethra with the implantation of a rectangular preputial or oral mucosa free graft. Recurrent urethral fistula after stitching was observed in 10 boys (25.6 %) of the first group, and only in 2 cases (4.3 %) in children with the augmentation of the urethral plate (p <0.05). The decrease of urine flow according to the data of uroflowmetry was observed in 15 patients (52 %) the first group, the children of the second group did not have a decrease in the flow of urine.Discussion. The shape, size of the glans and the condition of the urethral plate affect to the result of urethroplasty. The connection of the wings of the glans in accordance with normal anatomy, avoid obstruction in the distal part of urethra. A wide urethra in the glans and meatal area improves urine flow. Conclusion. The augmentation of the urethral plate of the penile glans and the distal urethra with the implantation of a wide rectangular free flap in to the meatus, in our opinion, an advantage over the implantation of diamond-shaped grafts using the GTIP or TIP graft technique.
39
Kyzlasov, P. S., A. T. Mustafaev, D. V. Ostrovsky, and A. G. Martov. "Temporary urethral stent with perineal fixation for posterior urethral stenosis (preliminary results)." Vestnik Urologii 9, no. 2 (July 10, 2021): 80–85. http://dx.doi.org/10.21886/2308-6424-2021-9-2-80-85.
Full textAbstract:
Introduction. Urethroplasty is the “gold standard” treatment of urethral stenosis. However, often in connection with old and senile age, as well as due to the presence of concomitant diseases, it is not possible to carry out urethroplasty due to its certain invasiveness. In such cases, one of the methods of treatment is the installation of a urethral stent. But this method has not found practical application due to the frequent migration of stent and the high frequency of its incrustation. The approach developed by us avoids stent migration.Purpose of the study. To evaluate the immediate results of the placement of a urethral stent with fixation through the perineum.Materials and methods. A total of 18 patients with urethral stenosis aged 68 to 84 years have been operated on since February 2019. Ten patients had stenosis of the urethrocystoneoanastomosis after radical prostatectomy, 6 patients had iatrogenic stenosis of the prostatic urethra, 1 patient had post-radiation stenosis of the bulbo-membranous urethra. All patients in the preoperative and postoperative periods underwent: IPSS-QoL questioning, uroflowmetry, bladder ultrasound with residual urine volume evaluation, urethroscopy, ascending and micturition urethrocystography. The first stage was an internal optical urethrotomy according to the standard technique. Then, a urethral stent was installed in the area of dissected stenosis. The second stage was an incision in the perineum, the urethra was isolated, and under optical control, through the perineum, the stent was fixed to the urethra with non-absorbable suture material. The stent was removed endoscopically after 6 months.Results. The median surgery duration averaged 45 minutes. Patients were discharged 2 to 3 days after surgery. The maximum observation period was 20 months. During the observation period, not a single case of stent migration was recorded. All patients showed a persistent increase in Qmax and no residual urine. Six patients had a stress component of urinary incontinence, 4 patients had total urinary incontinence. According to control urethrocystoscopy 6 months after stent removal, clinically insignificant urethral stenosis was noted in all patients. In all cases, moderate signs of stent encrustation were identified. Dysuric phenomena disturbed 5 patients, who were stopped by rectal suppositories with NSAIDs, as well as taking herbal uroseptics. The data from the IPPS-QoL questionnaires confirm the positive effect of the treatment.Conclusions. Temporary placement of a urethral stent for urethral stenosis is an effective minimally invasive treatment. The technique of fixation through the perineum allows preventing migration in all cases. This approach to treatment significantly improves the quality of life of patients who were contraindicated for urethroplasty for one reason or another. However, the technique requires longer observation and analysis.
40
Mira, Jose L., and Guang Fan. "Leiomyoma of the Male Urethra." Archives of Pathology & Laboratory Medicine 124, no. 2 (February 1, 2000): 302–3. http://dx.doi.org/10.5858/2000-124-0302-lotmu.
Full textAbstract:
Abstract We describe the case of a 48-year-old quadriplegic black man with history of C4-C5 cervical spine and cord injury secondary to a fall, who presented to the University of Cincinnati Medical Center Urology Service with obstructive symptoms at urination. A bulbous urethral stricture was diagnosed and subsequently resected with primary urethral reanastomosis. On pathologic examination, the surgical specimen contained an epithelioid leiomyoma at the site of the urethral stricture. Although leiomyomas of the female urethra are relatively common, we identified only 2 previously reported cases of leiomyomas of the male urethra in the English-language medical literature. To the best of our knowledge, we describe the third case of leiomyoma of the male urethra, the first of the epithelioid type.
41
PAPAZOGLOU (Λ.Γ. ΠΑΠΑΖΟΓΛΟΥ), L. G., and E. BASDANI (Ε. ΜΠΑΣΔΑΝΗ). "Perineal urethrostomy in the cat. Technique and complications." Journal of the Hellenic Veterinary Medical Society 62, no. 2 (November 10, 2017): 150. http://dx.doi.org/10.12681/jhvms.14846.
Full textAbstract:
Perineal urethrostomy (PU) is the surgical procedure performed in the male cat in order to create a permanent stoma of the pelvic urethra to the skin of the perineal region. The first urehrostomy was devised on early sixties and since then many urethrostomy techniques were invented. On 1971 Wilson and Harrison invented a technique of PU that is currently used by the majority of surgeons, because of the better results and fewer complications compared to the other urethrostomy techniques. Indications for performing PU in the male cat include recurrent urethral obstruction associated with lower urinary tract disease, as an emergency procedure for the restoration of the patency of the obstructed urethra when all other conservative measures failed, priapism, strictures, trauma and urethral neoplasms. For a successful PU: 1) the pelvic urethra should be incised and anastomosed in the perineum cranial to the bulbourethral glands, 2) the urethra should be completely freed from its attachments to the ishium so as to decrease tension to the stoma, and 3) accurate apposition of the urethra to the skin should be performed to achieve first intention healing of the stoma site and avoid stricture formation. Complications following PU may include urethral stricture, ascending urinary tract infection, haemorrhage, subcutaneous urine extravasation resulting in sloughing and dehiscence of the stoma, skin fold dermatitis, urinary and fecal incontinence, bladder atony, iatrogenic perineal hernia and rectourethral fistula. Prepubic, subpubic or transpelvic urethrostomy may be used to salvage postoperative urethral stricture. Pepubic urethrostomy is the only salvage technique that has been evaluated long-term, but is associated with serious complications such as urine scalding, urinary incontinence and urinary tract infection. Perineal urethrostomy aims at relieving urethral obstruction and is part of the medical management of cats with recurrent or persistent urethral plug formation.
42
Lee, Perry, and Jordana Haber. "Urethral Calculi." Clinical Practice and Cases in Emergency Medicine 4, no. 2 (February 24, 2020): 134–36. http://dx.doi.org/10.5811/cpcem.2019.5.43182.
Full textAbstract:
Urolithiasis is a condition with calculi commonly found within the kidney, ureter, or bladder. The urethra is an uncommon location of urolithiasis, with limited case reports and literature reviews of its presentation and management. Here we discuss a 24-year-old female who presented with urinary urgency, flank pain, and urinary retention for 12 hours. Physical exam showed a calculus at the urethral meatus. This case discusses the manual removal of a urethral calculus in a female patient with use of forceps, resulting in complete resolution of symptoms and urinary retention.
43
Kamo, Izumi, Kazumasa Torimoto, Michael B. Chancellor, William C. de Groat, and Naoki Yoshimura. "Urethral closure mechanisms under sneeze-induced stress condition in rats: a new animal model for evaluation of stress urinary incontinence." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 285, no. 2 (August 2003): R356—R365. http://dx.doi.org/10.1152/ajpregu.00010.2003.
Full textAbstract:
The urethral closure mechanism under a stress condition induced by sneezing was investigated in urethane-anesthetized female rats. During sneezing, while the responses measured by microtip transducer catheters in the proximal and middle parts of the urethra increased, the response in the proximal urethra was almost negligible when the bladder response was subtracted from the urethral response or when the abdomen was opened. In contrast, the response in the middle urethra during sneezing was still observed after subtracting the bladder response or after opening the abdomen. These responses in the middle urethra during sneezing were significantly reduced ∼80% by bilateral transection of the pudendal nerves and the nerves to the iliococcygeous and pubococcygeous muscles but not by transection of the visceral branches of the pelvic nerves and hypogastric nerves. The sneeze leak point pressure was also measured to investigate the role of active urethral closure mechanisms in maintaining total urethral resistance against sneeze-induced urinary incontinence. In sham-operated rats, no urinary leakage was observed during sneeze, which produced an increase of intravesical pressure up to 37 ± 2.2 cmH2O. However, in nerve-transected rats urinary leakage was observed when the intravesical pressure during sneezing exceeded 16.3 ± 2.1 cmH2O. These results indicate that during sneezing, pressure increases elicited by reflex contractions of external urethral sphincter and pelvic floor muscles occur in the middle portion of the urethra. These reflexes in addition to passive transmission of increased abdominal pressure significantly contribute to urinary continence mechanisms under a sneeze-induced stress condition.
44
Riaz-ul-Haq, Muhammad, Arslan Raza Wasati, Mazhar Rafi, Sohail Jamil, Binish Naeem, and Yasir Sultan. "LIMITED URETHERAL MOBILIZATION PROCEDURE (LUMP) FOR DISTAL PENILE HYPOSPADIAS REPAIR, A SINGLE CENTRE RETROSPECTIVE ANALYSIS." International Journal of Advanced Research 9, no. 5 (May 31, 2021): 1335–43. http://dx.doi.org/10.21474/ijar01/12977.
Full textAbstract:
Background: Distal penile hypospadias is one of the commonest varieties of hypospadias. Different techniques have been mentioned in literature. The success rate is usually assessed by rate of fistula formation and over all cosmetic appearance and functional outcome. Limited Uretheral Mobilization Procedure (LUMP) for distal penile hypospadias is considered a good technique with almost zero fistula rate in some series. As no new urethral tube is constructed there is no risk of fistula. Objective: To evaluate the results of the Limited Urethral Mobilization Procedure (LUMP) for distal hypospadias repair. Methods.It is retrospective analysis of 32 patients aged up to 12 years who were treated with Limited urethral mobilization procedure for distal penile hypospadias in the Department of Paediatric Surgery Jinnah Hospital Lahore from December 2018 to November 2019. All patients were operated under general anesthesia. The urethra proximal to the meatus was mobilized adequately in such a way that it should reach the tip of glans easily without any ventral bending of penis.Then the urethra was placed in the glandular wings and reconstruction of glans was carried out. Dartos flap was also placed to cover the urethra as a safety measure to avoid urethrocutaneous fistula formation. Follow up was done for a period of 3 months with respect to fistula formation, meatal stenosis, retraction , chordee and over all cosmetic appearance. Results: Age range of children was 9 months to 12 years. Operation time ranged from 60-80 minutes. Seven of 32 cases were previously operated for distal penile hypospadias but after disruption of repair meatus was lying at coronal or subcoronal level. They also underwent LUMP. Five cases had minor chordee, it was corrected at the time of uretheral mobilization by simple excision of fiberous tisse in 4 patients while modified Nesbit dorsal placation was done in one. Cosmetically normal looking circumcised penis with slit like meatus was achieved in all.Two cases got superficial wound infection, two had meatal stenosis, one meatal retraction, one ventral chordee and one urethrocutaneous fistula. Conclusion: LUMP for distal penile hypospadias is a simple and effective procedure with minimum complications.There is no chance for development of urethrocutaneous fistula, a major postoperative complication of other surgical techniques for uretheroplasty. Postoperative management is simple and hospital stay is short.
45
RUS, Vasile, Bianca MATOSZ, and Flavia RUXANDA. "The Structure of Urethral Epithelium in Merinos Lambs." Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Veterinary Medicine 75, no. 1 (May 19, 2018): 123. http://dx.doi.org/10.15835/buasvmcn-vm:000917.
Full textAbstract:
The aim of this study was to investigate by histological techniques the structure of urethral epithelium in lambs. In this study, we harvested several fragments (prostatic, membranous and cavernous) from urethra from 5 merino’s lambs of 3 months old. The first anatomical segment, the prostatic urethra, is lined by a urinary epithelium. The intermediary layer of this epithelium is formed of 5-6 rows of oval cells. The second segment of urethra has the same type of epithelium but the intermediary layer is formed of 6-7 rows of oval cells. In the last anatomical segment, the penile urethra, the epithelium is the same, but the intermediary layer has 3-4 rows of oval cells. In lambs, the urethra is lined by urinary epithelium. The urethral epithelium does not have the same thickness in all segments. The thinner epithelium it is in the cavernous urethra, the ticker is the membranous urethra.
46
Ryan, John D., Evelyn Toh, Julie A. Brothwell, Yuan Sun, Stephen J. Jordan, and David E. Nelson. "24435 Pathogen-specific metabolic pathways and innate immune responses associated with Chlamydia trachomatis infection and other STIs." Journal of Clinical and Translational Science 5, s1 (March 2021): 87–88. http://dx.doi.org/10.1017/cts.2021.627.
Full textAbstract:
ABSTRACT IMPACT: This project seeks to identify unique host responses that are biomarkers for specific urethral pathogens, and which can be used in the development of point-of-care (POC) STI diagnostics. OBJECTIVES/GOALS: How Chlamydia trachomatis (CT) and other common STIs, e.g. Neisseria gonorrhoeae, evade immunity and elicit pathology in the male urethra is poorly understood. Our objective is to determine how STI-infected urethral epithelial cells, as well as the uninfected ‘bystander’ cells with which infected cells communicate, respond to CT and other STIs. METHODS/STUDY POPULATION: We evaluated how immortalized urethral cell lines - including transduced human urethral epithelial cells (THUECs) - respond to increasing doses of CT infectious particles using in vitro one-step progeny assays performed in the presence or absence of cycloheximide, a drug that inhibits eukaryotic protein synthesis. We will perform concurrent single-cell RNA sequencing (scRNA-seq) and multiplex cytokine analyses to determine how different CT doses impact the transcriptomes of infected and bystander urethral epithelial cells and modulate cytokine production of the overall monolayer. Results of these experiments will inform the feasibility of performing similar analyses in situ using urethral swabs from men with clinically diagnosed urethritis. RESULTS/ANTICIPATED RESULTS: Our results demonstrate that immune-competent urethral cell monolayers strongly resist CT infection, unless most of the cells are simultaneously infected. This suggests that uninfected bystander cells sense CT-infected cells and secrete soluble factors that may act to limit CT proliferation in infected cells and to inform remaining uninfected cells that a potential pathogen is present. We anticipate that our scRNA-seq and cytokine analyses will identify both specific effector pathways that protect against CT and intracellular signals that modulate them. We speculate that these pathways and signals may differ during infection with CT and other STIs. Importantly, we anticipate that our in vitro model of CT infection will be highly representative of in situ immune responses observed in urethras of infected men. DISCUSSION/SIGNIFICANCE OF FINDINGS: In men, common STIs including CT are usually managed syndromically due to a lack of POC diagnostics. By determining how STIs elicit urethral inflammation and identifying countermeasures that STIs use to evade urethral immunity, we can identify host responses that serve as biomarkers for urethritis, generally, and for specific urethral pathogens.
47
Vorobev, V. A., V. A. Beloborodov, and S. L. Popov. "Double Urethral Valve: a Clinical Case." Creative surgery and oncology 8, no. 3 (January 26, 2019): 231–36. http://dx.doi.org/10.24060/2076-3093-2018-8-3-231-236.
Full textAbstract:
Introduction. Urethral valves (UVs) are congenital malformations of the urethra, leading to infravesical obstruction. The most common UV is the posterior urethral valve (PUV). The anterior urethral valve (AUV) is a somewhat rarer, but still well-known congenital anomaly. UVs can provoke significant obstruction of the proximal urinary system, which can later lead to disability of children and more frequent deaths.Materials and methods. The article presents a clinical example of a 32-year-old man with a congenital double urethral valve occuring in the anterior and posterior urethra, which led to the development of chronic urinary retention, urinary tract infection and chronic renal failure. The patient underwent a successful urethroplasty operation to remove the valve mechanism.Results. Six months following surgery, the patient noted the complete disappearance of symptoms, with renal function having returned to normal. No signs of recurrence of the disease or the formation of stricture of the urethra were detected by to the survey.Conclusion. A congenital variant of the double UV is an unusual extremely rare cause of infravesical obstruction. Early diagnosis and treatment of this anomaly is very important for preventing further irreversible damage to the urinary system. The presented clinical observation demonstrates the need to organise and conduct periodic preventive examinations of children of different age groups.
48
Ben Salem, Amina, Ines Mazhoud, Rachida Laamiri, Randa Salem, Hayet Laajili, and Chiraz Hafsa. "Anterior Urethral Valve: Uncommon Association with Renal Duplicity." Journal of Neonatal Surgery 6, no. 2 (April 15, 2017): 41. http://dx.doi.org/10.21699/jns.v6i2.544.
Full textAbstract:
Anterior urethral valves (AUVs) is an unusual cause of congenital obstruction of the male urethra, being 15–30 times less common than posterior urethral valves. We present a case of AUV diagnosed at 24th gestational week. Ultrasonography and fetal MRI revealed hydronephrotic kidneys with ureteral duplicity, a distended bladder and perineal cystic mass which confirmed dilated anterior urethra in a male fetus. Diagnosis was confirmed postnatally by voiding cystourethrogram and surgery.
49
Mosa, Hazem, and Massimo Garriboli. "Congenital Anterior Urethrocutaneous Fistula with a Persistent Urethral Groove." European Journal of Pediatric Surgery Reports 09, no. 01 (January 2021): e9-e12. http://dx.doi.org/10.1055/s-0040-1721469.
Full textAbstract:
AbstractCongenital anterior urethrocutaneous fistula (CAUF) is a rare penile anomaly with only 63 cases reported in the literature. The anomaly can present in isolation or in association with chordee or hypospadias. We report the case of an 8-month-old boy with CAUF that resembles the embryological urethral groove. On examination, a wide urethral groove was noted to cover the midshaft of the penis with a well formed urethra extending proximally and distally and with a normal glandular anatomy, a wide glandular meatus, and a complete foreskin. The urethral groove was tubularized and covered in layers. Surgery was complicated with early superficial skin dehiscence not affecting the urethral repair.Refashioning of the skin was then performed. A satisfactory aesthetic and functional outcome was observed at 7 years' follow-up. Defining the anatomy of CAUF and distal urethra is key in management of these children.
50
Marzoli, E., G. Tigano, C. Andrisani, L. Cavarretta, and A. Cacciola. "A case of giant urethral storie." Urologia Journal 63, no. 1 (February 1996): 137–38. http://dx.doi.org/10.1177/039156039606300127.
Full textAbstract:
— The Authors report a case of giant urethral stone, localised in one of the penile urethra diverticula. Statistically urethral stones are less than 1 % of all urinary stone cases and do not present particular diagnostic or therapeutic problems. We have presented this case solely for its rarity.