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1

Kronig, Sophia A. J., Otto D. M. Kronig, Marcel Zurek, and Léon N. A. Van Adrichem. "Orbital volume, ophthalmic sequelae and severity in unilateral coronal synostosis." Child's Nervous System 37, no. 5 (February 10, 2021): 1687–94. http://dx.doi.org/10.1007/s00381-021-05065-3.

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Abstract Purpose Unilateral coronal synostosis (UCS) results in an asymmetrical skull, including shallow and asymmetrical orbits, associated with reduced orbital volume and high prevalences of ophthalmic sequelae. Aim is to link orbital volumes in patients with UCS to severity according to UCSQ (Utrecht Cranial Shape Quantifier) and presence of ophthalmic sequelae. Methods We included preoperative patients with UCS (≤ 18 months). Orbital volume was measured on CT scans by manual segmentation (Mimics software (Materialise, Leuven, Belgium)), and severity of UCS was determined by UCSQ. Orbital volume of affected side was compared to unaffected side using Wilcoxon signed rank test. Orbital volume ratio was calculated (affected/unaffected volume) and compared to the category of UCSQ by Kruskal-Wallis test. Opthalmic sequelae were noted. Results We included 19 patients (mean age 7 months). Orbital volume on affected side was significantly lower (p = 0.001), mean orbital volume ratio was 0.93 (SD 0.03). No significant differences in group means of orbital volume ratio between different levels of severity of UCSQ were found (Kruskal-Wallis H (2) = 0.873; p > 0.05). Ophthalmic sequelae were found in 3 patients; one had adduction impairment and strabismus (mild UCS), one had astigmatism (moderate UCS), and one had abduction impairment (on both ipsi- and contralateral side) and vertical strabismus (severe UCS). Conclusion No association between orbital volume ratio and severity of UCS was found. Side-to-side asymmetry in orbital volume was noted. No association between either preoperative orbital volume ratio or severity of UCS and the presence of preoperative ophthalmic sequelae was found.
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2

Sagee, Shira, Amir Sherman, Galit Shenhar, Kenneth Robzyk, Noa Ben-Doy, Giora Simchen, and Yona Kassir. "Multiple and Distinct Activation and Repression Sequences Mediate the Regulated Transcription of IME1, a Transcriptional Activator of Meiosis-Specific Genes inSaccharomyces cerevisiae." Molecular and Cellular Biology 18, no. 4 (April 1, 1998): 1985–95. http://dx.doi.org/10.1128/mcb.18.4.1985.

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ABSTRACT IME1 encodes a transcriptional activator required for the transcription of meiosis-specific genes and initiation of meiosis in Saccharomyces cerevisiae. The transcription ofIME1 is repressed in the presence of glucose, and a low basal level of IME1 RNA is observed in vegetative cultures with acetate as the sole carbon source. Upon nitrogen depletion a transient induction in the transcription of IME1 is observed in MATa/MATα diploids but not in MAT-insufficient strains. In this study we demonstrate that the transcription of IME1 is controlled by an extremely unusual large 5′ region, over 2,100 bp long. This area is divided into four different upstream controlling sequences (UCS). UCS2 promotes the transcription of IME1 in the presence of a nonfermentable carbon source. UCS2 is flanked by three negative regions: UCS1, which exhibits URS activity in the presence of nitrogen, and UCS3 and UCS4, which repress the activity of UCS2 in MAT-insufficient cells. UCS2 consists of alternate positive and negative elements: three distinct constitutive URS elements that prevent the function of any upstream activating sequence (UAS) under all growth conditions, a constitutive UAS element that promotes expression under all growth conditions, a UAS element that is active only in vegetative media, and two discrete elements that function as UASs in the presence of acetate. Sequence analysis of IME1 revealed the presence of two almost identical 30- to 32-bp repeats. Surprisingly, one repeat, IREd, exhibits constitutive URS activity, whereas the other repeat, IREu, serves as a carbon-source-regulated UAS element. The RAS-cyclic AMP-dependent protein kinase cAPK pathway prevents the UAS activity of IREu in the presence of glucose as the sole carbon source, while the transcriptional activators Msn2p and Msn4p promote the UAS activity of this repeat in the presence of acetate. We suggest that the use of multiple negative and positive elements is essential to restrict transcription to the appropriate conditions and that the combinatorial effect of the entire region leads to the regulated transcription ofIME1.
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3

Sandin, Bonifacio, and Paloma Chorot. "Resistance to Extinction of Conditioned Electrodermal Responses: A Study of the Incubation Fear Hypothesis." Psychological Reports 91, no. 1 (August 2002): 37–46. http://dx.doi.org/10.2466/pr0.2002.91.1.37.

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In the present study we examined Eysenck's incubation hypothesis of fear. Probability of skin conductance response (SCR) was analyzed for a sample of 79 undergraduate women, ranging in age from 18 to 25 years. Different groups of participants were conditioned to two levels of unconditioned stimuli (UCS) intensity and presented to three levels of unreinforced conditioned stimuli (CS) exposures (extinction phase) in a delay differential conditioning paradigm. The CSs were fear-relevant slides (snakes and spiders) and the UCSs were aversive tones. Analysis did not show a clear incubation effect; instead an increased resistance to extinction of SCR probability in association to the high-UCS and the short unreinforced CS presentation was evident. Findings support partially Eysenck's incubation theory of fear/anxiety.
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4

Cima, Gianluca, Maurizio Lenzerini, and Antonella Poggi. "Answering Conjunctive Queries with Inequalities in DL-Lite." Proceedings of the AAAI Conference on Artificial Intelligence 34, no. 03 (April 3, 2020): 2782–89. http://dx.doi.org/10.1609/aaai.v34i03.5666.

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In the context of the Description Logic DL-Liteℛ≠, i.e., DL-Liteℛ without UNA and with inequality axioms, we address the problem of adding to unions of conjunctive queries (UCQs) one of the simplest forms of negation, namely, inequality. It is well known that answering conjunctive queries with unrestricted inequalities over DL-Liteℛ ontologies is in general undecidable. Therefore, we explore two strategies for recovering decidability, and, hopefully, tractability. Firstly, we weaken the ontology language, and consider the variant of DL-Liteℛ≠ corresponding to rdfs enriched with both inequality and disjointness axioms. Secondly, we weaken the query language, by preventing inequalities to be applied to existentially quantified variables, thus obtaining the class of queries named UCQ≠,bs. We prove that in the two cases, query answering is decidable, and we provide tight complexity bounds for the problem, both for data and combined complexity. Notably, the results show that answering UCQ≠,bs over DL-Liteℛ≠ ontologies is still in AC0 in data complexity.
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5

James, Jijo. "A Micro-Level Investigation of Optimum Lime-Content Stabilized Expansive Soil Amended with Organic Coconut Shell Powder." Slovak Journal of Civil Engineering 28, no. 1 (March 1, 2020): 1–10. http://dx.doi.org/10.2478/sjce-2020-0001.

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AbstractThe experimental investigation involved stabilizing an expansive soil using lime, amending the stabilization process with varying doses of coconut shell powder (CSP), and studying the effects of the amendment on the strength, index properties, mineralogy, and microstructure of the stabilized soil. The optimum lime content (OLC) for the maximum strength gain of the stabilized soil was determined by performing unconfined compressive strength (UCS) tests. The stabilization process was amended with four different proportions of CSP, and the UCSs of the amended specimens were evaluated and compared. The spent UCS samples were crushed and pulverized to perform index property tests as well as mineralogical (XRD) and micro-structural (SEM) tests. The results of the investigation revealed that amending the lime stabilization process with CSP yielded positive results only at a low dosage of 0.25%. It is concluded that materials of an organic origin such as CSP need to be adopted in low dosages to reap beneficial effects in the stabilization process.
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6

Chun, Se-Hak, and Yong-Hwan Byun. "Success Factors of UCSD CONNECT as Business Incubator." Journal of Digital Convergence 13, no. 1 (January 28, 2015): 135–49. http://dx.doi.org/10.14400/jdc.2015.13.1.135.

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7

&NA;. "UCSF study." Orthopaedic Nursing 15, no. 4 (July 1996): 64. http://dx.doi.org/10.1097/00006416-199607000-00014.

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8

Sun, Kai, Lu Shuang Wei, Li Xuan, and Lun Gang Zhou. "Study on Establishment and Transformation of Coordinate System of Steel Structure in 3D Software." Applied Mechanics and Materials 501-504 (January 2014): 2541–45. http://dx.doi.org/10.4028/www.scientific.net/amm.501-504.2541.

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The 3D visualization design of steel structure under the CAD environment needs to work in the global coordinate system (WCS), but design of various steel members in the 3D space must be completed in the local coordinate system (UCS), so it is perplexing for the conversion and calculation between UCSi (i=1,2,3....n) and WCS. It is proved that the maize grains are not polluted and food production is in safe condition. The article describes classification of several common coordinate systems, discuss the method of setting up coordinates system. Describe the process of type convertion of coordinate system in steel structure design and detailing softwares, and explained the advantage of the application in the real world project.
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9

Melisko, Michelle E., Edward Kenji Hadeler, Sandahl H. Nelson, Audrey Lunde, Irene Acerbi, Hope S. Rugo, Melanie Catherine Majure, Amy Jo Chien, Laura Esserman, and Sheri J. Hartman. "Objective assessment of physical activity during chemotherapy for breast cancer." Journal of Clinical Oncology 35, no. 15_suppl (May 20, 2017): TPS6626. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.tps6626.

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TPS6626 Background: Exercise can alleviate side effects of chemotherapy, improve quality of life (QOL), and positively impact disease specific and overall survival. Despite the benefits of physical activity (PA), many patients’ activity levels decrease during chemotherapy. Wearable devices, such as the Fitbit, can provide insight into patterns of activity, and help encourage behavior change. The aims of this study are: 1) determine the feasibility/acceptability of using a Fitbit to measure PA and sleep throughout chemotherapy for breast cancer; 2) describe patterns of PA, sedentary time, and sleep during chemotherapy; 3) explore associations of activity and sleep with QOL. Methods: Non-metastatic breast cancer patients from UCSF and UCSD will be enrolled prior to starting chemotherapy. Eligibility criteria include ability to speak/read English, walk unassisted, and access to internet or Fitbit compatible smart phone. Patients sign informed consent, receive a Fitbit Charge HR and guidance on how to use the device. Patients are instructed to wear the Fitbit throughout their adjuvant or neoadjuvant chemotherapy and 6 months post therapy and to sync the Fitbit at least weekly. Patients complete surveys at start, midpoint, end, and 6 months post chemotherapy. Questionnaires include PROMIS anxiety, depression, physical function, fatigue, cognitive function, social roles, comfort with technology and usefulness of the Fitbit. Fitabase database collects minute level activity, sleep, and heart rate. To assess feasibility, we will evaluate if a participant wears FitBit for at least 10 hour per day for ≥ 80% of the days during chemotherapy. We will use mixed effects regression models to assess patterns of PA and associations between activity and QOL. All models will include activity time and Fitbit wear time and will control for the potential confounding effects of age and other demographic or clinical variables. As of February 6 2017, 48 out of a planned 80 patients are enrolled. Acknowledgment: Athena Breast Health Network investigators and patients; support at UCSD by NCI (U54 CA155435-01) and by gift from Carol Vassiliadis and family; NCI grant K07CA181323 to SH; UCSF M Zion Health Fund Award, GBCTB unrestricted funding and TriValley SOCKS to MM. Clinical trial information: NCT03041545.
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10

ROVNER, SOPHIE. "UCSD SELECTS FOX." Chemical & Engineering News 82, no. 16 (April 19, 2004): 9. http://dx.doi.org/10.1021/cen-v082n016.p009.

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11

Barinaga, Marcia. "UCSF space problem." Nature 327, no. 6118 (May 1987): 91. http://dx.doi.org/10.1038/327091b0.

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12

Wallerstein, R. "Psychiatry at UCSF." Science 263, no. 5149 (February 18, 1994): 901. http://dx.doi.org/10.1126/science.8310283.

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13

Weiner, H. "Psychiatry at UCSF." Science 263, no. 5149 (February 18, 1994): 901. http://dx.doi.org/10.1126/science.8310284.

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14

Friedkin, Morris, and William S. Allison. "Nate at UCSD." Analytical Biochemistry 161, no. 2 (March 1987): 243–44. http://dx.doi.org/10.1016/0003-2697(87)90447-7.

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15

Zweig, Ann S., Donna Karolchik, Robert M. Kuhn, David Haussler, and W. James Kent. "UCSC genome browser tutorial." Genomics 92, no. 2 (August 2008): 75–84. http://dx.doi.org/10.1016/j.ygeno.2008.02.003.

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16

Barinaga, Marcia. "Court ruling pleases UCSF." Nature 336, no. 6201 (December 1988): 706. http://dx.doi.org/10.1038/336706a0.

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17

Feder, Toni. "UCSC to Get Grades." Physics Today 53, no. 4 (April 2000): 57. http://dx.doi.org/10.1063/1.883039.

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18

Hsu, F., W. J. Kent, H. Clawson, R. M. Kuhn, M. Diekhans, and D. Haussler. "The UCSC Known Genes." Bioinformatics 22, no. 9 (February 24, 2006): 1036–46. http://dx.doi.org/10.1093/bioinformatics/btl048.

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19

Feder, Toni. "UCSC Adaptive Optics Lab." Physics Today 55, no. 11 (November 2002): 31. http://dx.doi.org/10.1063/1.4796557.

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20

Messina, L. M., and C. K. Zarins. "UCSF Stanford Vascular Symposium." Perspectives in Vascular Surgery and Endovascular Therapy 16, no. 3 (September 1, 2004): 156. http://dx.doi.org/10.1177/153100350401600302.

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21

Osherovich, Lev. "Herding catalysts at UCSF." Science-Business eXchange 7, no. 8 (February 2014): 216. http://dx.doi.org/10.1038/scibx.2014.216.

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22

Hsu, F. "The UCSC Proteome Browser." Nucleic Acids Research 33, Database issue (December 17, 2004): D454—D458. http://dx.doi.org/10.1093/nar/gki100.

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23

Glaser, Vicki. "UCSF targets cancer IND." Nature Biotechnology 16, no. 4 (April 1998): 328. http://dx.doi.org/10.1038/nbt0498-328.

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24

Rohn, Jennifer. "Genentech, UCSF discovery pact." Nature Biotechnology 28, no. 5 (May 2010): 386. http://dx.doi.org/10.1038/nbt0510-386.

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25

Wandschneider, G., R. Petek, K. Pummer, and G. Primus. "The permanent ureterocutaneostomy (UCST)." International Urology and Nephrology 24, no. 4 (July 1992): 381–87. http://dx.doi.org/10.1007/bf02550630.

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26

Mukerji, Chandra. "Joe Gusfield at UCSD." American Sociologist 48, no. 1 (July 7, 2016): 8–13. http://dx.doi.org/10.1007/s12108-016-9328-7.

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27

Ogdon, Will. "UCSD at Darmstadt 1988." Perspectives of New Music 27, no. 2 (1989): 300. http://dx.doi.org/10.2307/833421.

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28

Hafiz, Chems Eddine. "Responsabilité pour faute d’une UCSA." Droit, Déontologie & Soin 17, no. 3 (September 2017): 300–304. http://dx.doi.org/10.1016/j.ddes.2017.07.019.

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29

Di Bias, A., D. M. Dahle, M. Diekhans, L. Grate, J. Hirschberg, K. Karplus, H. Keller, et al. "The UCSC Kestrel parallel processor." IEEE Transactions on Parallel and Distributed Systems 16, no. 1 (January 2005): 80–92. http://dx.doi.org/10.1109/tpds.2005.12.

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30

Shurkin, Joel. "UCSF lands a lucky strike." Nature Medicine 1, no. 7 (July 1995): 613. http://dx.doi.org/10.1038/nm0795-613a.

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31

Greenspan, John S., Marcus A. Conant, John L. Ziegler, Paul A. Volberding, and Yvonne G. DeSouza. "The UCSF AIDS Specimen Bank." Laboratory Medicine 22, no. 11 (November 1, 1991): 790–92. http://dx.doi.org/10.1093/labmed/22.11.790.

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32

Russell, David E. "The UCSB Humanistic Psychology Archive." Journal of Humanistic Psychology 30, no. 4 (September 1990): 57–61. http://dx.doi.org/10.1177/002216789003000406.

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33

Carson, Dennis A. "NCI NanoTumor Center at UCSD." Nanomedicine: Nanotechnology, Biology and Medicine 3, no. 4 (December 2007): 332–36. http://dx.doi.org/10.1016/j.nano.2007.10.002.

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34

Zhu, Jingchun, J. Zachary Sanborn, Stephen Benz, Christopher Szeto, Fan Hsu, Robert M. Kuhn, Donna Karolchik, et al. "The UCSC Cancer Genomics Browser." Nature Methods 6, no. 4 (April 2009): 239–40. http://dx.doi.org/10.1038/nmeth0409-239.

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35

Eblenkamp, M., J. Aigner, J. Hintermair, S. Potthoff, U. Hopfner, V. Jacobs, M. Niemeyer, and E. Wintermantel. "Umbilical Cord Stromal Cells (UCSC)." Der Orthopäde 33, no. 12 (December 2004): 1338–45. http://dx.doi.org/10.1007/s00132-004-0730-4.

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36

Karjalainen, Erno, Vladimir Aseyev, and Heikki Tenhu. "Counterion-Induced UCST for Polycations." Macromolecules 47, no. 21 (October 28, 2014): 7581–87. http://dx.doi.org/10.1021/ma501924r.

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37

Tiznado, Denisse, Brent T. Mausbach, Veronica Cardenas, Dilip V. Jeste, and Thomas L. Patterson. "UCSD SORT Test (U-SORT)." Journal of Nervous and Mental Disease 198, no. 12 (December 2010): 916–19. http://dx.doi.org/10.1097/nmd.0b013e3181fe75b6.

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38

Karolchik, D. "The UCSC Genome Browser Database." Nucleic Acids Research 31, no. 1 (January 1, 2003): 51–54. http://dx.doi.org/10.1093/nar/gkg129.

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39

BARINAGA, M. "The Sports Stars of UCSF." Science 245, no. 4925 (September 29, 1989): 1442. http://dx.doi.org/10.1126/science.245.4925.1442.

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40

Schneider, K. L. "The UCSC Archaeal Genome Browser." Nucleic Acids Research 34, no. 90001 (January 1, 2006): D407—D410. http://dx.doi.org/10.1093/nar/gkj134.

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41

Renault, Beatrice. "A new Salk–UCSD institute?" Nature Medicine 6, no. 5 (May 2000): 489. http://dx.doi.org/10.1038/74941.

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42

Laursen, Lucas. "UCSD researcher shot by cofounder." Nature Biotechnology 31, no. 11 (November 2013): 952. http://dx.doi.org/10.1038/nbt1113-952a.

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43

Paulson, K. P. "Micro-undulator research at UCSB." Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 296, no. 1-3 (October 1990): 624–30. http://dx.doi.org/10.1016/0168-9002(90)91278-j.

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44

Millikan, R. C. "UCSB molecular modeling instructional project." Journal of Molecular Graphics 9, no. 1 (March 1991): 43. http://dx.doi.org/10.1016/0263-7855(91)80041-w.

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45

Meftah, El Mehdi, and Lucie Rispal-Padel. "Reverse Effects of Conditioning Produced by Two Different Unconditioned Stimuli on Thalamocortical Transmission." Journal of Neurophysiology 77, no. 4 (April 1, 1997): 1663–78. http://dx.doi.org/10.1152/jn.1997.77.4.1663.

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Meftah, El Mehdi and Lucie Rispal-Padel. Reverse effects of conditioning produced by two different unconditioned stimuli on thalamocortical transmission. J. Neurophysiol. 77: 1663–1678, 1997. Actions of cerebellothalamocortical (CTC) networks on the musculature can be modified by associative conditioning in adult animals. During conditioning, electrical stimulation of a CTC network involved in forearm flexion movements results in either flexion or extension responses, depending on the somatosensory information given by the unconditioned stimulus (UCS). In the present work we attempt to determine what kind of neurobiological changes induced in the CTC pathways as a consequence of distinct somesthetic messages could lead to different conditioned motor responses. Two conditioning procedures in which distinct UCSs were successively applied to awake cats in chronic preparation. The conditioned stimulus (CS) was an electrical subthreshold stimulation of an interpositus nucleus (IN) site at the origin of CTC circuits controlling forelimb flexion movements. It was first paired with a UCS applied to the skin above the wrist, also producing a forearm flexion reflex, and second with a UCS applied more proximally on the forearm, producing a backward withdrawal reflex of the forelimb. The two procedures, termed “concordant” and “discordant,” respectively, were carried out in a different order on the same cats, separated by 2 mo of rest. The effects of conditioning were assessed from the characteristics of the motor reponses induced by the CS and from the properties of the CTC transmission analyzed on the cortical field potentials induced by IN stimulation. The concordant procedure resulted in persistent enhancement of the amplitude and rate of occurrence of the forearm flexions induced by the CS. Concomitantly, an increase of the di- and/or trisynaptic excitatory negative component of the field potentials induced by the CS in layers III and V of the elbow motor cortical representation was observed. In contrast, during the discordant procedure, the forearm flexions initially induced by the IN stimulation were progressively abolished in favor of forearm extensions, and, in parallel, a depression of the excitatory negative component of the cortical responses and the appearance of a later large positive event were observed. The selectivity and the associative nature of the motor and synaptic changes were tested. The two kinds of events appeared to be linked. It was concluded that somesthetic information given by the UCS seems to be a critical factor in the determination of both the motor and synaptic CTC changes induced by associative conditioning. Alterations of cerebellocortical transmission appeared to constitute one of the neurobiological substrates for conditioned motor changes.
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46

UCSH, Escuela de Administración y. Economía. "School of Management and Economics UCSH." Oikos 19, no. 40 (May 4, 2016): 10. http://dx.doi.org/10.29344/07184670.40.963.

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47

Small, Eric J., Katherine A. Harris, Mark W. Frohlich, and Robert Bok. "The UCSF advanced prostate cancer program." Urologic Oncology: Seminars and Original Investigations 6, no. 5 (September 2001): 197–201. http://dx.doi.org/10.1016/s1078-1439(01)00137-5.

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48

Mäkinen, Lauri, Divya Varadharajan, Heikki Tenhu, and Sami Hietala. "Triple Hydrophilic UCST–LCST Block Copolymers." Macromolecules 49, no. 3 (January 19, 2016): 986–93. http://dx.doi.org/10.1021/acs.macromol.5b02543.

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49

Goddard, Thomas D., Conrad C. Huang, and Thomas E. Ferrin. "Visualizing density maps with UCSF Chimera." Journal of Structural Biology 157, no. 1 (January 2007): 281–87. http://dx.doi.org/10.1016/j.jsb.2006.06.010.

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50

Kent, W. J., C. W. Sugnet, T. S. Furey, K. M. Roskin, T. H. Pringle, A. M. Zahler, and a. D. Haussler. "The Human Genome Browser at UCSC." Genome Research 12, no. 6 (May 16, 2002): 996–1006. http://dx.doi.org/10.1101/gr.229102.

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