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ZUCCHETTI, FIONA. "Transposon based technology in DHFR knockout CHO cell line improves generation of AMH high producing clones for industrial applications." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2018. http://hdl.handle.net/10281/198952.
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In ricerca ed in applicazione industriale la richiesta di proteine ricombinanti è in continua crescita; vengono investite sempre più risorse per sviluppare un sistema efficace in grado di ottenere un’elevata espressione proteica.Le cellule di mammifero sono l’ospite di elezione per lo sviluppo di proteine ricombinanti in quanto ne garantiscono la qualità.Linee cellulari CHO deficitarie dell’enzima diidrofolato reduttasi(DHFR) sono molto diffuse come sistema di espressione.In tali linee, il DHFR, un enzima essenziale coinvolto nella sintesi di purine, viene sfruttato come marker di selezione. È possibile aumentare la pressione selettiva con il metotrexate, molecola che presenta un’attività inibitoria sul DHFR.L’inibizione spinge le cellule ad amplificare il gene DHFR come meccanismo di resistenza, ne consegue una contestuale amplificazione del gene di interesse presente nella cassetta di espressione del plasmide. Grazie al progresso della tecnologia del DNA ricombinante, sono state recentemente sviluppate, linee cellulari knockout per il gene DHFR. Dati preliminari, ottenuti nel nostro laboratorio, hanno dimostrato che utilizzando il sistema del trasposone piggyBac(PB) è possibile migliorare la frequenza di cloni alto-producenti rispetto al metodo di trasfezione convenzionale. Il progetto di ricerca ha avuto come primo obiettivo quello di valutare se la potenzialità del trasposone si esprimesse anche nella linea cellulare DHFR knockout e di analizzare gli effetti del processo di amplificazione sul transgene integrato, comparandolo con i vettori convenzionali. Lo scopo finale era l’ottenimento di cloni alto-producenti dell'ormone anti-Mulleriano(AMH). AMH è una glicoproteina dimerica che causa la regressione dei dotti Mulleriani negli embrioni maschili ed è utilizzata come marker diagnostico nella riproduzione assistita. I dati indicano che il sistema del trasposone risulta essere più efficiente rispetto al vettore standard nell’ottenere un’elevata espressione proteica e consentendo l’integrazione di un numero maggiore di copie del transgene e la stabilità genetica nel tempo. Nonostante il miglioramento ottenuto, la resa proteica nello scale-up non è stata soddisfacente. Pertanto, ci siamo concentrati sui costrutti per aumentare la produttività e potenziare l’amplificazione genica. Abbiamo sperimentato strategie volte a ridurre l'attività del DHFR agendo sulla sua via di espressione. Anche se l'inserimento di un IRES meno efficiente ha permesso di ottenere dati incoraggianti, la resa proteica non è risultata paragonabile a quella riportata in letteratura. Inoltre, l’indebolimento della via di espressione del DHFR ha reso difficile la crescita delle colture cellulari scoraggiando un'ulteriore esplorazione. Abbiamo quindi valutato gli elementi regolatori epigenetici per migliorare l’efficienza trascrizionale.Ottimi risultati sono stati ottenuti in pool di cellule trasfettate con i vettori contenenti gli UCOE.Sono stati infatti raggiunti elevati livelli di espressione proteica dimostrando il sostanziale effetto di queste sequenze. Per caratterizzare ulteriormente gli UCOE, abbiamo isolato alcuni cloni. Lo scopo era evidenziare differenze tra questi nuovi vettori ed il trasposone precedentemente utilizzato. L'obiettivo finale è stato raggiunto.Abbiamo, infatti, isolato un clone ad alta produttività caratterizzato sia dalla stabilità genetica sia da quella dell’espressione nel tempo.In conclusione, l’utilizzo di una linea cellulare DHFR knockout in associazione con il sistema del trasposone PB ha permesso di ottenere una buona espressione della proteina ricombinante AMH.Il trasposone si è confermato un sistema efficiente per incrementare l'espressione proteica; l'utilizzo dell’elemento regolatore epigenetico UCOE non solo ha permesso un ulteriore e significativo aumento della resa proteica, ma anche un rigoroso mantenimento della stabilità genetica e dell’espressione nel tempoThe claim of recombinant protein continues to increase for both research and industrial application. More and more resources are invested to develop the most efficient system for high protein expression. Mammalian cells are the best host for quality and reliability of expressed recombinant proteins. A diffuse protein production technology is based on dihydrofolate reductase (DHFR) deficient CHO cell line expression system. DHFR is an essential enzyme involved in purines synthesis and it is used as a selection marker. This technology has the potentiality to strength the selection process by inhibiting DHFR activity with methotrexate (MTX), forcing cells to amplify the DHFR gene and the gene of interest carried by the plasmid used for transfection. Thanks to the continuous progression in recombinant DNA technology, DHFR knockout cell lines are recently developed using different molecular tools. Preliminary data showed that by using the piggyBac (PB) transposon system it is possible to enhance the frequency of high producing clones compared to conventional transfections. In order to evaluate if PB transposon potentiality also occur in DHFR knockout cell line and to analyze the effects of amplification process on integrated transgene, research plan involved the comparison of the conventional gene transfer method to the PB transposon system. Our aim was to explore PB transposon in the DHFR knockout CHO expression system to obtain clones producing high yield of anti-Mullerian hormone (AMH) protein for industrial purposes. AMH is a dimeric glycoprotein, member of the TGFβ superfamily that causes regression of Mullerian ducts in male embryos. It has a fundamental role as diagnostic marker in assisted reproduction to predict ovarian reserve. The PB transposon system resulted a more efficient method to obtain high protein expression compared to standard vector. Moreover, it allowed higher performance in gene copy number integration and genetic stability than standard transfection method. In spite of the substantial improvement obtained by this new approach, AMH protein yield in scale-up was unsatisfactory. Therefore, we focused on construct engineering to increase productivity, since a higher MTX gene amplification was expected. Strategies to reduce the DHFR activity acting on its expression pathway were performed to enhance the AMH protein production. Even though encouraging data were obtained with the insertion of a less efficient IRES, achieved AMH protein yield was not comparable to what reported in literature exploiting the same approaches. Moreover, difficulties in culturing cells due to DHFR expression pathway impairments discouraged a further exploration. Thus, we decided to shift our focus on epigenetic regulatory elements in order to force transcriptional efficiency. Impressive results were obtained in cell pools transfected with vectors carrying the UCOEs, in which high protein expression levels were reached, thus demonstrating the valid impact of these sequences. To further characterize the UCOE we decided to isolate single cell clones from the cell pool derived from the transposon with one UCOE sequence. We aimed to highlight differences between this new vector and our previous PB transposon. We reached the final goal to isolate a high-producing clone, which guaranteed expression and genetic stability over time. In conclusion, in this work a new generated DHFR knockout cell line was exploited in association with the piggyBac transposon system to achieve high expression of recombinant protein. The PB transposon system was confirmed to be a powerful method to enhance the expression of AMH protein allowing higher performances in gene copy number integration and genetic stability compared to the standard transfection method. Employing epigenetic regulatory elements, such as the UCOE, not only a substantial increase in AMH protein yield was achieved, but also expression and genetic stability was strictly conserved over time
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Wong, Chi-kin Felix, and 黃子鍵. "Ubiquitous chromatin opening element (UCOE)-mediated human coagulationFactor IX secretion by lentiviral transduction of human mesenchymalstem cells." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hub.hku.hk/bib/B50713255.
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Haemophilia B is a bleeding disorder caused by various mutations of the coagulation Factor IX gene (F9) resulting in qualitative or quantitative Factor IX protein (FIX) deficiency. Factor replacement therapy is the current standard of care. Cure may be possible in the near future by gene therapy — the transfer of normal copies of F9 to patients with haemophilia, causing establishment of FIX production and correction of the bleeding phenotype. Mesenchymal stem cells (MSC) are potential vehicles for gene delivery through ex vivo gene transfer and subsequent transplantation to the patient. Lentiviral vectors can transduce MSC effectively and mediate long term gene expression. However, gene expression may decline with time due to transgene silencing. Ubiquitous Chromatin Opening Element (UCOE) is a set of genetic sequences cloned from housekeeping genes that can maintain a transcriptionally competent, open chromatin structure and was shown to prevent gene silencing by resisting DNA methylation.
We tested human F9 expression and FIX protein secretion by transducing MSC with lentiviral vectors that carry the FIX gene under the control of A2UCOE (A2UCOE-hF9). A2UCOE is a 2.2 kb sequence cloned from the HNRPA2B1–CBX3 gene loci that harbour UCOE function. A2UCOE-eGFP, an enhanced Green Fluorescent Protein (eGFP) gene expression construct, was used to assist in vector titration of A2UCOE-hF9 by flow cytometry and quantitative reverse transcription-polymerase chain reaction (qRT-PCR). MSC were transduced at various Multiplicities of Infection (MOIs) by A2UCOE-hF9 lentiviral vector. Upon transduction, F9 mRNA expression and FIX secretion were measured by qRT-PCR and ELISA respectively. Osteogenic and adipogenic differentiation assay were performed to compare differentiation potential before and after transduction at an MOI of 1.
F9 mRNA expression and FIX secretion were both undetectable in untransduced MSC. Upon transduction, vector dose-dependent increase in F9 mRNA expression and FIX secretion were detected at MOIs of 1, 2, 4 and 8. The level of secreted FIX ranges from 20 to 150 μIU in 72 hours. Osteogenic and adipogenic differentiation were not affected post-transduction at an MOI of 1.
In conclusion, FIX secretion by MSC was detected upon A2UCOE-hF9 lentiviral transduction. However, the level of FIX appeared to be low compared to published studies. Further studies are required to determine the cause of low FIX expression, develop methods to maximize FIX expression and confirm whether A2UCOE can prevent gene silencing and maintain sustainable gene expression.published_or_final_version
Paediatrics and Adolescent Medicine
Master
Master of Research in Medicine
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Hassinger, Elena. "Compétition d'états fondamentaux dans URu2Si2 et UCoGe." Phd thesis, Université de Grenoble, 2010. http://tel.archives-ouvertes.fr/tel-00533732.
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Dans cette thèse, deux composés à fermions lourds ont été étudiés sous pression. L'état fondamental en dessous de T0 = 17.5 K dans URu2Si2 est appelé "ordre caché (HO), parce que le paramètre d'ordre n'a pas encore été trouvé. A 1.5 K, le système devient en plus supraconducteur. Sous pression, le système devient antiferromagnetique (AF) au dessus d'une pression critique. Des mesures Shubnikov-de Haas sous pression montre, que la surface de Fermi ne change pas entre les deux phases. Dans la phase AF, le dédoublement de la maille implique une reconstruction de la surface de Fermi. Vu que celle-ci ne change pas sous pression, ce dédoublement doit avoir lieu déjà dans l'HO. Nos mesures de la dépendance angulaire des fréquences d'oscillation supportent des nouveau calcules de bande dans le cas d'électrons plutôt itinérant. Comme deuxième partie de ma thèse, j'ai étudié le diagramme de phase sous pression du supraconducteur (SC) ferromagnétique (FM) UCoGe (TC = 2.8 K,Tsc = 0.6 K). Les mesures de résistivité, ac calorimétrie et ac susceptibilité montrent que la phase FM est supprimé a environs 1 GPa mais la phase SC existe jusque dans la phase paramagnétique induite par la pression. Ce diagramme de phase est unique dans la classe des supraconducteurs ferromagnétiques.
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Wu, Beilun. "Unconventional superconductivity in the ferromagnetic superconductor UCoGe." Thesis, Université Grenoble Alpes (ComUE), 2017. http://www.theses.fr/2017GREAY010/document.
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Cette thèse discute essentiellement sur le champ critique supérieur du supraconducteur ferromagnétique UCoGe. La conductivité thermique et d'autres méthodes expérimentales ont été utilisées pour confirmer les nombreux comportements particuliers de Hc2 dans UCoGe, précédemment observés dans des études de résistivité. Ces caractéristiques, y compris une anisotropie forte et des courbures anormales, ne peuvent pas être interprétées en termes de théories classiques pour Hc2. Au lieu de cela, un phénomène spécifique aux supraconducteurs ferromagnétiques - la dépendance en champ de l'interaction d'appariement doit être considéré. Nous montrons que cet effet peut être analysé de façon cohérente avec des propriétés de la phase normales et peut être aussi comparé quantitativement avec une théorie existante. Ceci conduit à une clarification nette pour le cas de H//c dans UCoGe, et explique en même temps le comportement différent de Hc2 dans UCoGe et URhGe. Ces résultats soutiennent fortement l'origine magnétique de la supraconductivité dans ces systèmes. Pour H//b, nous montrons que certaines observations expérimentales convergentes suggèrent un possible changement d'état supraconducteur induit par le champ magnétique transversal dans UCoGe. Indépendamment du reste de l'étude, le dernier chapitre présente quelques résultats expérimentaux sur la phase normale de UCoGe et sur l'autre système de fermions lourds UBe13This thesis mainly discuss the upper critical field of the ferromagnetic superconductor UCoGe.Thermal conductivity and other experimental methods have been used to confirm the numerous particularbehaviors of Hc2 in UCoGe, previously observed in resistivity studies. These features, including the stronganisotropy and the anomalous curvatures, cannot be interpreted in terms of classical theories for Hc2.Instead, a phenomenon specific to the ferromagnetic superconductors - the field dependence of the pairinginteraction, needs to be considered. We show that this effect can be consistently analyzed with normalphase properties, and is quantitatively compared with existing theory. This leads to a net clarificationfor the case of H//c in UCoGe, and at the same timeexplains the different behavior of Hc2 in UCoGe and URhGe. These resultsstrongly support the magnetic origin of superconductivity in these systems. For H//b, we showconvergent experimental observations that suggest a possible change of the superconducting state inducedby the transverse magnetic field in UCoGe. Independent from the rest of the study, the last chapter presents someexperimental results on the normal phase of UCoGe and on the other heavy-fermion system UBe13
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Li, Feng. "Bewertung von Ausbaumaßnahmen zur Engpassbeseitigung im UCTE-Verbundnetz /." Aachen : Klinkenberg Verl, 2005. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=014188256&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
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Hattori, Taisuke. "Spin-Triplet Superconductivity Induced by Ferromagnetic Fluctuations in UCoGe." 京都大学 (Kyoto University), 2014. http://hdl.handle.net/2433/188471.
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Araujo, Santos Ana Luisa de. "uCom : spatial displays for visual awareness of remote locations." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/55199.
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Thesis (S.M.)--Massachusetts Institute of Technology, School of Architecture and Planning, Program in Media Arts and Sciences, 2009.Cataloged from PDF version of thesis.
Includes bibliographical references (p. [113]-116).
uCom enables remote users to be visually aware of each other using "spatial displays" - live views of a remote space assembled according to an estimate of the remote space's layout. The main elements of the system design are a 3D representation of each space and a multi-display physical setup. The 3D image-based representation of a space is composed of an aggregate of live video feeds acquired from multiple viewpoints and rendered in a graphical visualization resembling a 3D collage. Its navigation controls allow users to transition among the remote views, while maintaining a sense of how the images relate in 3D space. Additionally, the system uses a configurable set of displays to portray always-on visual connections with a remote site integrated into the local physical environment. The evaluation investigates to what extent the system improves users' understanding of the layout of a remote space.
by Ana Luisa de Araujo Santos.
S.M.
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Camy, Alexandre Rosa. "Aplicação do modelo UCON abc em sistemas de comércio eletrônico B2B." Florianópolis, SC, 2005. http://repositorio.ufsc.br/handle/123456789/102447.
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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduaçõa em Ciência da Computação.Made available in DSpace on 2013-07-16T00:58:32Z (GMT). No. of bitstreams: 1 220823.pdf: 1700842 bytes, checksum: 339544c3cbf00d6d06566d73e3518766 (MD5)
Recentemente foi proposto um modelo de controle de acesso, denominado UCONABC, que além de unir alguns dos principais conceitos de controle de acesso ainda propõe novos conceitos como: obrigações, condições, continuidade e mutabilidade. Apesar de abrangente, o UCONABC possui limitações e existem ainda muitas melhorias a serem pesquisadas, como por exemplo, a definição de uma forma adequada da aplicação deste modelo em Sistemas de Comércio Eletrônico (CE) Business-to-Business (B2B). Publicações científicas nesta área afirmam que são necessárias pesquisas na especificação, validação e execução de políticas de controle de acesso para sistemas B2B. Esta dissertação possui como principal contribuição científica a proposta de uma forma de aplicação do UCONABC em sistemas de CE B2B que interajam entre si. Além disso, é proposto o Agrupamento Implícito Parcial, uma técnica que facilita o gerenciamento de permissões neste tipo de sistema. A aplicabilidade da proposta desta dissertação é apresentada através de uma descrição detalhada da implementação de um sistema de CE B2B onde o controle de acesso segue as especificações desta proposta. Por fim, é apresentado um estudo de caso em que é possível visualizar, através de um exemplo do mundo real, a aplicação da proposta desta dissertação neste tipo de sistema.
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Taupin, Mathieu. "Etude des fermions lourds magnétiques UCoGe et YbRh2Si2 par mesures de transport." Phd thesis, Grenoble, 2013. http://tel.archives-ouvertes.fr/tel-01026388.
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Les mesures de conduction thermique ont été effectuées à basses températures dans le supraconducteur ferromagnétique UCoGe et dans le composé faiblement antiferromagnétique YbRh2Si2. Les fluctuations magnétiques sont un élément important dans les propriétés de ces deux composés, et sont responsables d'un canal de chaleur à basses températures. Dans UCoGe, la contribution supplémentaire causée par les fluctuations magnétiques ont la même dépendance en champ magnétique que celles vues par RMN. Étonnamment, un nouveau canal de chaleur apparaît à très basses températures. Les mesures dans l'état supraconducteur ont confirmé le caractère multigap de UCoGe. Des mesures de XMCD ont également faites dans UCoGe. Dans YbRh2Si2, les fluctuations magnétiques sont suspectées d'être responsables d'un canal de chaleur visible à très basses températures, empêchant de pouvoir conclure sur la violation ou la validité de la loi de Wiedemann-Franz au niveau du point critique quantique. Cependant, les résultats peuvent être interprétés sans avoir recours à sa violation.
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君島, 健之. "ucodeを用いたコンクリートの品質トレーサビリティの研究." 京都大学 (Kyoto University), 2011. http://hdl.handle.net/2433/151988.
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Manago, Masahiro. "Enhancement of Spin-Triplet Superconductivity by Pressure-Induced Critical Ferromagnetic Fluctuations in UCoGe." Kyoto University, 2019. http://hdl.handle.net/2433/242592.
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Taufour, Valentin. "Croissance de cristaux de composés à base d'uranium et étude de UGe2." Phd thesis, Université de Grenoble, 2011. http://tel.archives-ouvertes.fr/tel-00639652.
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Cette thèse porte sur l'étude du composé supraconducteur ferromagnétique UGe$_2$. La croissance de monocristaux de UGe$_2$ a été réalisée dans un four tétra-arc par la technique du tirage Czochralski. Cette technique a également servie à l'obtention d'autres composés à base d'uranium, notament UCoGe et URu$_2$Si$_2$. Pour la première fois, la structure avec des ailes (wings) du diagramme de phase de UGe$_2$ a été vérifiée expérimentalement. Cette observation est une conséquence d'une température de transition ferromagnétique qui décroît par application d'un paramètre extérieur tel que la pression, et qui devient du premier ordre avant de disparaître. Le changement d'ordre se fait à un point tricritique. D'autres mesures ont porté sur la transition supraconductrice qui se produit à l'intérieur de la phase ferromagnétique. La nature volumique de la supraconductivité a été confirmé et l'accent s'est porté sur son renforcement sous champ magnétique.
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Howald, Ludovic. "Interactions entre la supraconductivité et la criticité quantique, dans les composés CeCoIn5, URhGe et UCoGe." Phd thesis, Université de Grenoble, 2011. http://tel.archives-ouvertes.fr/tel-00584598.
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Le sujet de cette thèse est l'analyse du second champ critique supraconducteur (Hc2) ainsi que l'interaction entre la supraconductivité et les points critiques quantiques (PCQ), pour les composés CeCoIn5, URhGe et UCoGe. Dans le composé CeCoIn5, l'étude par résistivité du domaine de liquide de Fermi a permis la localisation précise du PCQ a pression ambiante. Cette analyse permet d'invalider l'hypothèse d'une coïncidence entre Hc2(0) et le PCQ. Dans une deuxième partie, l'évolution sous pression de Hc2 est analysée. Le dôme supraconducteur de ce composé est non-conventionnel avec deux pressions caractéristiques différentes: à ~1.6GPa, la température de transition supraconductrice est maximum alors que c'est à ~0.4GPa que la plupart des grandeurs physiques (maximum de Hc2(0), maximum de la pente dHc2/dT, maximum du saut de chaleur spécifique DC/C, ...) suggèrent la présence d'un PCQ. Nous expliquons cet antagonisme par l'importance des processus de brisure de pairs liés a la proximité du PCQ. Ces deux observations nous permettent de proposer un nouveau diagramme de phase pour CeCoIn5. Dans une troisième partie, les mesures de conduction thermique sur les composés URhGe et UCoGe sont présentées. Elles nous permettent dans un premier temps d'obtenir la transition "bulk" supraconductrice et de confirmer la forme in-habituelle de Hc2 observée en résistivité. La dépendance en températures et en champs de la conduction thermique nous permet d'identifier une contribution non-électronique au transport de chaleur jusqu'aux plus basses températures. D'autre part, nous identifions deux différents domaines supraconducteurs a bas et hauts champs appliqués selon l'axe b. Ces deux domaines sont compatibles avec un modèle de supraconductivité multigaps. Suivant ces observations et des mesures de pouvoir thermoélectrique, nous proposons un modèle de transition de Lifshitz pour ces deux composés.
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Bastien, Gaël. "Interplay between magnetic quantum criticality, Fermi surface and unconventional superconductivity in UCoGe, URhGe and URu2Si2." Thesis, Université Grenoble Alpes (ComUE), 2017. http://www.theses.fr/2017GREAY005/document.
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Cette thèse montre de nouveaux résultats sur les supraconducteurs ferromagnétiques UCoGe et URhGe et sur l’ordre caché dans URu2Si2. Le diagramme de phase pression température d’UCoGe a été étudié jusqu’à 10.5 GPa. L’ordre ferromagnétique subsiste jusqu’à la pression critique pc≈1 GPa et la supraconductivité non conventionnelle jusqu’à p = 4 GPa. Les fluctuations magnétiques responsables de la supraconductivité peuvent être réduites par l’application d’un champ magnétique. Les surfaces de Fermi d’UCoGe et d’URhGe ont été mesurées grace aux oscillations quantiques. Quatre poches ont été détectées dans UCoGe, elles subissent une succession de transition de Lifshitz de la surface de Fermi sous champ magnétique. Les poches détectés évoluent continument avec la pression jusqu’à 2.5 GPa, sans montrer de reconstruction de la surface de Fermi à la pression critique pc. Dans URhGe, trois poches lourdes de la surface de Fermi ont aussi été découvertes. Enfin dans la phase d’ordre caché d’URu2Si2, les oscillations quantiques ont révélé une forte anisotropie du facteur gyromagnétique g pour deux poches de la surface de Fermi, qui est comparable à l’anisotropie macroscopique. Cette dernière a été étudiée à partir du champcritique supérieur de la supraconductivitéThis thesis is concentrated on the ferromagnetic superconductors UCoGe and URhGe andon the hidden order state in URu2Si2. In the first part the pressure temperature phase diagram of UCoGe was studied up to 10.5 GPa. Ferromagnetism vanishes at the critical pressure pc≈1 GPa. Unconventional superconductivity and non Fermi liquid behavior can be observed in a broad pressure range around pc. The superconducting upper critical field properties were explained by the suppression of the magnetic fluctuations under field. In the second part the Fermi surfaces of UCoGe and URhGe were investigated by quantum oscillations. In UCoGe four Fermi surface pockets were observed. Under magnetic field successive Lifshitz transitions of the Fermi surface have been detected. The observed Fermi surface pockets in UCoGe evolve smoothly with pressure up to 2.5 GPa and do not show any Fermi surface reconstruction at the critical pressure pc. In URhGe, three heavy Fermi surface pockets were detected by quantum oscillations. In the last part the quantum oscillation study in the hidden order state of URu2Si2 shows a strong g factor anisotropy for two Fermi surface pockets, which is compared to the macroscopic g factor anisotropy extractedfrom the upper critical field study
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Starck, Emilie. "La petite propriété dans l'oasis du Valle de Uco-Mendoza (Cuyo, Argentine)." Bordeaux 3, 2010. http://www.theses.fr/2010BOR30029.
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Le Valle de Uco est un oasis de piémont de la diagonale aride argentine. Dès la fin du XIXème siècle, l’arrivée en masse d’une main-d’œuvre immigrée européenne s’associa à un développement vitivinicole intense dans la province de Mendoza. Valle de Uco est un espace représentatif de l’adaptation humaine à un milieu inhospitalier. Le système d’irrigation ancien a créé une organisation sociale et un usage intensif du sol par les producteurs en relation constante avec le marché. Orientée par la « loterie économique » du jeu capitaliste, la société rurale locale constitue aujourd’hui l’une des campagnes riches d'Argentine, où la petite propriété est majoritaire. De plus, l’engouement récent des entreprises transnationales pour la vitiviniculture moderne a transformé le finage et les relations entre producteurs. Dans ce contexte, les petits paysans s’adaptent pour la survie du groupe familial. Dès lors, un espace contrôlé est-il un élément déterminant dans l’essoufflement de la pauvreté rurale ? Au travers de l’analyse des types de producteurs, basée sur des études de terrain, l’objectif est de comprendre les enjeux de la ruralité d’un oasis moderne. En référence au modèle de la paysannerie locale, la recherche entreprise dresse un état des lieux sur les réussites et les failles d’un espace totalement artificialisé. Le diagnostic rural du Valle de Uco propose une nouvelle base de réflexion quant à l’action publique et au développement agricole dans les zones arides et semi-arides non seulement en Argentine, mais aussi pour d’autres horizonsValle de Uco is a piedmont oasis belonging to the argentinan arid diagona. Since the end of the XIX th century, the massive arrival of european immigrant labour forces combined to an intense wine growing development in the Mendoza province. Valle de Uco is a representative area of human adaptation to an inhospitable environment. The old irrigation system has generated a social organization and an intensive use of soils by breeders in constant relation with the market. Directed by the « economic lottery » of the capitalist game, the local country society constitute nowdays one of the rich country of Argentina, where small property is prevailing. Beyond, the recent fad of transnational companies for the modern wine making has change the structure of country and the relations between producers. In this context, small producers adapt for the survival of the family group. Therefore, is a controled space a decisive element in the country poverty weakening? Through the types of producers analysis, based on ground studies, the goal is to better understand the rural life stakes of a modern oasis. In reference to the local peasantry model, the search engaged draw up an inventory and report on successes and failures of an area wholly man-made. The country diagnosis of the Uco Valle suggest a new thinking back ground about public action and agricultural development in arid and semiarid areas not only in Argentina, but also for other horizons
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Gourgout, Adrien. "Instabilités de surface de Fermi avec et sans transitions magnétiques : étude de URhGe, UPd2AI3, UCoGe et CeIrIn5." Thesis, Université Grenoble Alpes (ComUE), 2017. http://www.theses.fr/2017GREAY001/document.
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Dans cette thèse, j'ai étudié l'évolution de la surface de Fermi sous l'influence d'un champ magnétique dans des systèmes massifs facilement polarisables à basse température. La première partie est dévouée aux cas du supraconducteur ferromagnétique UCoGe et du supraconducteur paramagnétique CeIrIn5, où la surface de Fermi peut être modifiée sans transition magnétique. Dans UCoGe, plusieurs anomalies successives ont été détectées dans l'effet Seebeck, la résistivité et l'effet Hall, sans transition nette dans l'aimantation. L'observation d'oscillations quantiques montre que ces anomalies sont reliées à des changements de topologie de la surface de Fermi, aussi appelés transitions de Lifshitz. Dans CeIrIn5, une anomalie est détectée dans l'effet Seebeck à HM = 28 T et les oscillations quantiques observées en magnétométrie torque montrent qu'une transition de Lifshitz à lieu à ce champ.Dans la deuxième partie, j'ai étudié comment varie la surface de Fermi à travers une transition magnétique du premier ordre induite par le champ magnétique dans le supraconducteur ferromagnétique URhGe avec le champ selon l'axe de difficile aimantation b et le supraconducteur antiferromagnétique UPd2Al3 avec le champ dans le plan basal. Dans URhGe, l'effet Seebeck permet d'observer un changement de la surface de Fermi à la transition de réorientation des spins à HR = 11.75 T et avec la résistivité confirme le caractère premier ordre de la transition en plus de fournir la localisation dans le diagramme de phase du point tricritique. Dans UPd2Al3, une nouvelle branche de la surface de Fermi est observée dans les oscillations quantiques de de Haas-van Alphen dans l'état antiferromagnétique et l'effet Seebeck montre que la surface de Fermi change à la transition métamagnétique à HM = 18 T. En outre, quatre nouvelles branches sont observées dans la phase polarisée au delà de HM et qui ne peuvent être associées à celles calculées dans les états paramagnétique et antiferromagnétiqueIn this thesis, we have studied the evolution of the Fermi surface under the influence of a magnetic field in bulk materials that can be easily polarized at low temperature. The first part was devoted to the cases of the ferromagnetic superconductor UCoGe with a magnetic field applied along the easy magnetization c-axis and the paramagnetic superconductor CeIrIn5 with the field along the c-axis. In UCoGe, several successive anomalies were detected in resistivity, Hall effect and thermoelectric power, without any thermodynamic transition being detected in magnetization. The direct observation of quantum oscillations showed that these anomalies are related to topological changes of the Fermi surface, also known as Lifshitz transitions. In CeIrIn5, the thermoelectric power detected an anomaly at HM = 28 T and the quantum oscillations observed in torque magnetometry showed that a Lifshitz transition occurs at this field.In the second part of this thesis, we studied the evolution of the Fermi surface through first order magnetic transitions induced by magnetic field. In the ferromagnetic superconductor URhGe with the field applied along the hard magnetization b-axis and the antiferromagnetic superconductor UPd2Al3 with the field in the basal plane. In URhGe, the thermoelectric power allowed to observe a change in the Fermi surface at the spin reorientation transition at HR = 11.75 T defining the ferromagnetic state and along with resistivity confirmed the first order character of the transition as well as give a location of the tricritical point. In UPd2Al3, a new branch was observed in de Haas-van Alphen experiment in the antiferromagnetic phase and the thermoelectric power showed that the Fermi surface is reconstructed at the metamagnetic transition at HM = 18 T where the antiferromagnetic state is suppressed and could suggest that the Fermi surface changes before this transition. Additionally, four new branches were observed in the polarized paramagnetic phase, above HM, that cannot be associated with calculated branches in the paramagnetic of antiferromagnetic states
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Huang, Kevin. "Materials synthesis and investigation of itinerant ferromagnetism in the UCo₁-xFex Ge system." Diss., [La Jolla] : University of California, San Diego, 2009. http://wwwlib.umi.com/cr/ucsd/fullcit?p1473081.
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Thesis (M.S.)--University of California, San Diego, 2009.Title from first page of PDF file (viewed February 17, 2010). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.
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Hykel, Danny. "Microscopie à micro-squid : étude de la coexistence de la supraconductivité et du ferromagnétisme dans le composé UCoGe." Phd thesis, Université de Grenoble, 2011. http://tel.archives-ouvertes.fr/tel-00579514.
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Pendant la première année le microscope à microSQUID était mis en fonctionnement. On a avancé sur le plan cryogenique (dilution) et électronique (programmation de boucles de régulation et d'une détection synchrone). Les composants étaient testés à température ambiante et on est en train de tout tester à basse température. Une méthode était conçu pour déterminer la longueur de pénétration du champ magnétique dans un supraconducteur avec les données qui pourront être fait avec notre microscope. Ceci va être utilisé pour l'échantillon PrOs4Sb12. Il s'agit de trancher le débat sur la nature multibande de la supraconductivité dans ce composé. En deuxième année le developpement a continué, en particulière le microscope était mis à froid. Des différents problèmes due aux basses températures (mouvement de moteur, thermalisation, câblage) ont été resolues. Ensuite on a avancé sur le plan informatique, notamment le contrôle de differents composants. Pendant le deuxième année quelques images magnétique ont été faites, validant le concept. En troisième année on a commence a mésurer des domaines magnetiques d'un supraconducteur ferromagnetique (UCoGe) en Avril - Aout. On a obtenu des resultats tres interessants. Le même dispositif sera ainsi opérationnel pour l'imagerie de domaines dans des bolomètres supraconducteurs.
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Kanno, Wellington Massayuki. "Propriedades mecânicas do gesso de alto desempenho." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/88/88131/tde-21112010-084639/.
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O método Umedecimento, Compactação e Secagem (UCOS) (1, 2, 3) produz, a partir de gesso e água, um material de elevada resistência mecânica: até 90 MPa na compressão. Este trabalho apresenta o estudo do comportamento mecânico deste material e como a água, a temperatura, as impurezas e a microestrutura influenciam no seu comportamento. Durante o estudo da adesão intercristalina, foi encontrada presença de água confinada e que é responsável por grande parte da resistência mecânica. Para auxiliar o estudo, foi desenvolvido outro método: Empacotamento Direto do Dihidrato (EDD). Nesta metodologia, é produzido um material com a mesma resistência, porém com algumas diferenças no comportamento mecânico diferente. Através da elevada resistência mecânica alcançada pelos métodos UCOS e EDD, as aplicações do gesso podem ser ampliadas desde que o gesso conformado por tais métodos possuam confiabilidade e segurança. Para avaliar as propriedades mecânicas, a confiabilidade e a segurança de tal material, realizou-se o estudo dos mecanismos tenacificadores e da mecânica da fratura. Os mecanismos tenacificadores estudados neste trabalho são: controle da microestrutura (aumento da superfície de ruptura), introdução de fibras poliméricas (distribuição da tensão na ponta da trinca, ramificação da ponta da trinca e contenção da abertura da trinca) e introdução de adesivo polimérico (melhora a adesão entre cristais e distribui melhor a tensão na ponta da trinca). Os resultados mostram que os compósitos de gesso reforçados com fibras poliméricas e/ou adesivo polimérico possuem elevada resistência e comportamentos mecânicos distintos para cada tipo de compósito e método de conformação. Concluímos que, com o conhecimento adquirido, é possível intervir no processamento e na microestrutura, além de poder incorporar elementos a esse material para atender às condições de uma determinada aplicaçãoThe humidification, compaction and drying (Umedecimento, Compactação e Secagem UCOS) (1, 2, 3) method produces a high strength material from plaster and water: up to 90 MPa in compression. This work presents the study of mechanical properties of this material and how water, temperature, impurity and microstructure influence in its behavior. During the study of the intercrystalline adhesion force, we found the presence of confined water and that it accounts for great part of the strength. In order to aid the study, another method was developed: Direct Packaging of the Dihydrate (Empacotamento Direto do Dihidrato EDD). In this methodology, it produces a material with the same resistance, but with some difference in the mechanical behavior. Through the high strength reached by the UCOS and EDD methods, the plaster applications can be extended, since the set material by these methods are reliable and safe. In order to evaluate the mechanical properties, the reliability and the safety of these pieces, we performed the study of the fracture mechanics and the fracture toughening mechanisms. In this work, the studied toughening are: microstructure control (enlargement of the fracture surface), polymeric fiber reinforcement (tension distribution on the fracture tip, fracture tip deflection, and fiber bridging), and polymer adhesive reinforcement (they enhance the adhesion between crystals and better distribute the tension on the fracture tip). The results show that the plaster composites of polymeric fibers and/or polymer adhesive have high resistance, and different mechanical behaviors for each type of composite and setting method. Based on the acquired knowledge, we conclude that it is possible to interfere on the processing and on the microstructure, as well as reinforcements in this material to satisfy the needs of a specific application
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Zainal-Abidin-Murad, Sumaiya. "Production of biodiesel from used cooking oil (UCO) using ion exchange resins as catalysts." Thesis, Loughborough University, 2012. https://dspace.lboro.ac.uk/2134/10276.
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This study focuses on the development of novel two-stage esterification-transesterification synthesis of biodiesel from used cooking oil (UCO) using novel heterogeneous catalysts. The esterification of the UCO was investigated using three types of ion exchange resins catalysts including Purolite D5081, Purolite D5082 and Amberlyst 15. Of all the catalysts investigated, Purolite D5081 resin showed the best catalytic performance and was selected for further optimisation studies. From the optimisation study, it was found that the external and internal mass transfer resistance has negligible effect on the esterification reaction. At the optimum reaction conditions, Purolite D5081 achieved 92% conversion of FFA. During reusability study, the conversion of FFA dropped by 10% after each cycle and it was found that progressive pore blockage and sulphur leaching were dominant factors that decreased the catalytic performance of the Purolite D5081 catalyst. A kinetic modelling for FFA esterification was carried out using Purolite D5081 as a catalyst. Three types of kinetic models were investigated i.e. pseudo homogeneous (PH), Eley-Rideal (ER) and Langmuir-Hinshelwood-Hougen-Watson (LHHW). Experimental data obtained from the batch kinetic studies was successfully represented by the PH model and a good agreement between experimental and calculated values was obtained. The activation energy for esterification and hydrolysis reaction was found to be 53 and 107 kJ/moL. The transesterification of pre-treated cooking oil (P-UCO) was investigated using various types of heterogeneous catalysts including Purolite CT-122, Purolite CT-169, Purolite CT-175, Purolite CT-275, Purolite D5081, Diaion PA306s and Cs-supported heteropolyacids catalysts. Of all the catalysts investigated, Diaion PA306s catalyst showed the highest conversion of triglycerides and was selected for further optimisation studies. At the optimum reaction conditions, Diaion PA306s achieved ca. 75% of triglycerides conversion. During the reusability study, Diaion PA306s catalyst gave a similar conversion of triglycerides after being reused once. Therefore, it was concluded that the resin can be used several times without losing catalytic activity. Several purification methods have been investigated and dry washing method was chosen as the best alternative for biodiesel purification.
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Vicente, Julián Nicolás. "Análisis y caracterización del potencial productivo apícola en ecosistemas alternativos del Valle de Uco." Bachelor's thesis, Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias, 2017. http://bdigital.uncu.edu.ar/10344.
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Este trabajo analiza las posibilidades de un futuro aprovechamiento apícola en ciertas zonas poco consideradas en el sistema productivo actual. Se fundamenta en la creciente necesidad de recurrir a la trashumancia como una práctica tendiente a aumentar los rendimientos productivos, en lo que a cantidad y calidad de miel, como principal producto de la colmena, se refiere. El estudio se enmarca en un contexto actual, donde múltiples procesos sociales, económicos y culturales, que vienen aconteciendo en La provincia de Mendoza y principalmente en sus valles irrigados (lugar de asentamiento y concentración de la mayoría de los productores apícolas), resultan en una serie de modificaciones ambientales desfavorables para la actividad. Se experimentó con un apiario modelo de 100 colmenas móviles en una zona ubicada en el borde noroeste del Valle de Uco, cuyas características edafoclimáticas y los recursos florísticos con los que cuenta, vienen llamando la atención de algunos productores. Se demostró que el sistema natural considerado, el cual presenta ciertas modificaciones antrópicas, cuenta con una diversidad importante de especies florales de interés apícola y con escalonamiento progresivo en su floración. Se demostró que en condiciones climáticas adecuadas, como la acontecida en el periodo estival 2016-2017, puede brindar un rendimiento en kilogramos de miel por colmena, igual o superior al valor medio nacional.Fil: Vicente, Julián Nicolás. Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias.
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Teigão, Rafael Coninck. "Controle de uso de recursos em sistemas operacionais utilizando o modelo UCON ABC / Rafael Coninck Teigão ; orientador, Carlos Maziero." reponame:Biblioteca Digital de Teses e Dissertações da PUC_PR, 2007. http://www.biblioteca.pucpr.br/tede/tde_busca/arquivo.php?codArquivo=1417.
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Dissertação (mestrado) - Pontifícia Universidade Católica do Paraná, Curitiba, 2007Bibliografia: p. 69-73
Esta dissertação discorre sobre as necessidades modernas de controle de utilização de recursos em sistemas operacionais multi-usuários, e apresenta uma proposta de projeto para a implementação do modelo de controle de uso UCONABC em um sistema operacional
This work addresses the modern needs of resource utilization control in multi-user operating systems, and presents a project proposal for implementing the UCONABC usage control model in a real operating system, by using a grammar specifically created for
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La, Torre Cervantes Rorvik. "Análisis de falla de la represa Marcacocha del distrito de Uco provincia de Huari-Ancash." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2016. https://hdl.handle.net/20.500.12672/5728.
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Publicación a texto completo no autorizada por el autorEl documento digital no refiere asesor
Realiza los cálculos para verificar la estabilidad de la represa Marcacocha y deslizamiento de la estructura bajo el método clásico y el criterio técnico P.E.T. (Presa Elemental Triangular). Para aumentar la estabilidad y seguridad de la estructura se plantea una alternativa de solución, un modelo de contrafuerte que cumplirá con los reglamentos establecidos en la construcción de represas.
Trabajo de suficiencia profesional
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La, Torre Cervantes Rorvik, and Torre Cervantes Rorvik La. "Análisis de falla de la represa Marcacocha del distrito de Uco provincia de Huari-Ancash." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2016. http://cybertesis.unmsm.edu.pe/handle/cybertesis/5728.
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Publicación a texto completo no autorizada por el autorEl documento digital no refiere asesor
Realiza los cálculos para verificar la estabilidad de la represa Marcacocha y deslizamiento de la estructura bajo el método clásico y el criterio técnico P.E.T. (Presa Elemental Triangular). Para aumentar la estabilidad y seguridad de la estructura se plantea una alternativa de solución, un modelo de contrafuerte que cumplirá con los reglamentos establecidos en la construcción de represas.
Trabajo de suficiencia profesional
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Lu, Lu. "Technico-economic evaluation of used rolling oil treatment between UCO module and conventional process in China." Thesis, KTH, VA-teknik, Vatten, Avlopp och Avfall, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-99355.
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UCO (Ultra Clean Oil) module, an innovative adaption of existing used rolling oil treatment in the Aluminum industry, is being studied for its potential market in China. In this article, conventional used rolling oil treatment process in China has been evaluated and compared with the UCO module in technical and economic aspects. This article also discusses the effect of these two processes on the environment. The UCO module presented in this article, has the potential to significantly reduce the impurities in the used rolling oil and also save the cost for the raw materials, manpower, maintenance and operation for more than 1,600,000 Kr a year. With the new ― state of art‖ equipment, the UCO module has less negative effect on the environment. The UCO module appears to be more efficient but profitability was found to be lower than the conventional process in China.
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McLean, Michael M. "Phenyl Functionalized Sol-gel Silica Sorbent for Capillary Microextraction and Chromia-Based Sol-gel Ucon Stationary Phase for Capillary Gas Chromatography." Scholar Commons, 2014. https://scholarcommons.usf.edu/etd/5374.
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The first chapter of this thesis presents an introduction to sol-gel methodology whose usefulness as a synthetic route will be demonstrated with two applications in chromatography. The first application involves the fabrication of a capillary micro-extraction (CME) device by coating a phenyl functionalized extracting phase on the inner surface of a fused silica capillary for analyte pre-concentration. The device was coupled on-line to a RP-HPLC system and practicality was demonstrated using allergens as target analytes. The allergens chosen as model analytes are typically found in fragrance products and food. Most of the 26 fragrance allergens that are monitored by various government authorities have a phenyl organic moiety (a strong chromophore), thus making them appropriate probes for exploring the extraction efficiency of the coating using a UV detector. The CME device showed ppt level limit of detection which makes it suitable for trace analyses of allergens and similar compounds in a variety of matrices.
The second application explores the feasibility of using sol-gel derived chromia-based stationary phase in gas chromatographic columns. The organic moiety of the stationary phase was derived from Ucon 75-H-90,000 while the inorganic backbone was prepared using chromium(III) dichloride hydroxide - methacrylic acid - aqua complex, 40% in isopropanol/acetone . Usefulness of prepared chromia-based GC stationary phase was examined for petrochemical application. Promising results were obtained using aliphatic-aromatics, polyaromatic hydrocarbons, BTEX test mixture, cycloalkanes, branched alkanes and akylbenzenes. The column was able to perform without degradation despite being rinsed multiples times sequentially with the following solvents: dichloromethane, methanol, water and finally methanol again. Maximum theoretical plate number calculated is around 2,400 plates/m. The plate number clearly needs improvement but is a promising result for the newly explored chromia-based stationary phase. The maximum programmable temperature is 250oC which is comparable with similar commercially available polar stationary phases.
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Nwandu, McDonald Kelechi [Verfasser], and Gerhard [Gutachter] Droesser. "Akọ na Uche (Wisdom and Justifiability) of Preemptive-strike in Self-defense and Alternative Conflict Resolutions / McDonald Kelechi Nwandu. Gutachter: Gerhard Droesser." Würzburg : Universität Würzburg, 2012. http://d-nb.info/110282352X/34.
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Akram, Raja. "A user centric security model for tamper-resistant devices." Thesis, Royal Holloway, University of London, 2012. http://repository.royalholloway.ac.uk/items/aca52f8c-6233-4f73-a9da-025d25ab1295/1/.
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In this thesis, we propose a ubiquitous and interoperable device based on the smart card architecture to meet the challenges of privacy, trust, and security for traditional and emerging technologies like personal computers, smart phones and tablets. Such a device is referred as User Centric Tamper-Resistant Device (UCTD). To support the smart card architecture for the UCTD initiative, we propose the delegation of smart card ownership from a stringent centralised authority (i.e. the card issuer) to users. This delegation mandated the review of existing smart card mechanisms and their adequate modifications/improvements. Since the inception of smart card technology, the most prevalent ownership model in the smart card industry has been the Issuer Centric Smart Card Ownership Model (ICOM). The ICOM has no doubt played a pivotal role in the proliferation of the technology into various segments of modern life. However, it has been a barrier to the convergence of different services on a smart card. In addition, it might be considered as a hurdle to the adaption of smart card technology into a general-purpose security device. To avoid these issues, we propose citizen ownership of smart cards, referred as the User Centric Smart Card Ownership Model (UCOM). Contrary to the ICOM, it gives the power of decision to install or delete an application on a smart card to its user. The ownership of corresponding applications remains with their respective application providers along with the choice to lease their application to a card or not. In addition, based on the UCOM framework, we also proposed the Coopetitive Architecture for Smart Cards (CASC) that merges the centralised control of card issuers with the provision of application choice to the card user. In the core of the thesis, we analyse the suitability of the existing smart card architectures for the UCOM. This leads to the proposal of three major contributions spanning the smart card architecture, the application management framework, and the execution environment. Furthermore, we propose protocols for the application installation mechanism and the application sharing mechanism (i.e. smart card firewall). In addition to this, we propose a framework for backing-up, migrating, and restoring the smart card contents. Finally, we provide the test implementation results of the proposed protocols along with their performance measures. The protocols are then compared in terms of features and performance with existing smart cards and internet protocols. In order to provide a more detailed analysis of proposed protocols and for the sake of completeness, we performed mechanical formal analysis using the CasperFDR.
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Laudecina, Anabela. "Relación entre el régimen hidrológico superficial y los niveles de agua subterránea en el Valle de Uco, Mendoza." Bachelor's thesis, Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias, 2016. http://bdigital.uncu.edu.ar/7793.
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La cuenca del Valle de Uco, es un área con presentes conflictos de expansión y usos de su recurso hídrico, con una complejidad de actores sociales producto de las relaciones sociales profundamente desiguales y la concentración económica.
Este trabajo, está proyectado como una herramienta útil para el abordaje a futuro de un balance hídrico de la cuenca del Valle de Uco, proporcionando análisis espaciales y temporales de las variabilidades de los caudales y niveles estáticos involucrados, bajo la hipótesis planteada de que la hidrología superficial se vincula temporalmente, con la hidrología subterránea de la cuenca del Valle de Uco.
Para llevarlo a cabo se recopiló información de caudales medios mensuales históricos del río Tunuyán en la estación Valle de Uco y de los arroyos afluentes, como también de los niveles estáticos de agua subterránea de la red de pozos de monitoreo del Instituto Nacional del Agua. De esta manera se trabajó con los caudales medios anuales de 26 arroyos, desde el ciclo 1975/1976 hasta 1996/1997, y de los caudales medios del río Tunuyán desde 1972 hasta 2011, y con 225 pozos georreferenciados (POSGAR 94) y sus respectivas cotas de agua, desde 1972 hasta 2011.
La descripción de la relación entre las cuencas, superficial y subterránea, se realizó a través de análisis estadístico descriptivo, análisis geoestadístico, gráficos de evolución temporal, análisis de krigeado ordinario, mediante el sistema de información geográfica QGIS 2.10.1 y análisis de correlación lineal y análisis de regresión lineal simple.
Se concluyó que los caudales de los cauces superficiales de la cuenca del Valle de Uco se relacionan temporalmente con los niveles estáticos del agua subterránea de la cuenca. También se determinó que la variabilidad total de los niveles estáticos de la cuenca, responden de forma directa al la variabilidad del caudal del río Tunuyán y del arroyo Manzano.
Esta conexión entre el régimen hidrológico superficial y el subterráneo, es relevante al momento de tomar decisiones administrativas y/o de gestión, que involucren a cualquiera de las partes, o al sistema en sí. Este tipo de decisiones pueden ser: asignar mejor el recurso, detectar puntos donde son necesarias inversiones y mejoras en el sistema, proteger la calidad y cantidad del recurso hídrico y los ecosistemas relacionados, entre otros.Fil: Laudecina, Anabela. Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias.
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Teruya, Jorgelina Tsuneko. "Evaluación biofísica de servicios ecosistémicos en la cuenca del Arroyo Grande, Tunuyán, Mendoza." Bachelor's thesis, Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias, 2015. http://bdigital.uncu.edu.ar/16791.
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En el Valle de Uco (Mendoza, Argentina), se ha producido en los últimos años una reestructuración de los sistemas agroalimentarios, con un rápido avance de la frontera agrícola sobre el piedemonte. El estudio de los Servicios Ecosistémicos (SE), establece un vínculo explícito entre el bienestar humano y el adecuado funcionamiento del ecosistema (Balvanera et al., 2011).
El objetivo de este trabajo fue evaluar la capacidad funcional y la provisión relativa de SE, de los principales ecosistemas presentes en la cuenca del Arroyo Grande, que integra el Valle de Uco.
Se utilizó el protocolo ECOSER como base de cálculo de las funciones y servicios ecosistémicos. Se compiló información de textura de suelos, coberturas del terreno, modelo digital de elevaciones e imagen LANDSAT del 27/02/11. Con los cuales, mediante el sistema de información geográfica QGIS 2.6.1 Brighton, se calculó el NDVI (Índice de Vegetación de Diferencia Normalizada) y se localizaron espacialmente los tipos de ecosistemas dominantes (TED). Se consideraron cuatro funciones ecosistémicas (FE). La identificación de cada SE y su provisión relativa se calculó como la combinación lineal del flujo de cada FE ponderado por su aporte relativo al correspondiente SE, según propone el protocolo ECOSER. Por último, mediante la generación de mapas, se evaluó espacialmente la provisión de SE, identificando zonas de generación, propagación y captura, y su direccionalidad (in situ, direccional u omnidireccional).
Se diferenciaron dos tipos de ecosistemas dominantes, el Agroecosistema y el Monte Nativo. Respecto a los SE identificados, la producción agrícola (cultivos, ganadera y forestal), junto con la recarga de acuíferos, fueron los de mayor provisión. Los menos provistos por la cuenca son los de regulación climática y de calidad del aire.
Se concluyó que existen diferencias en la provisión de SE según los usos del suelo, siendo el Agroecosistema proveedor de un mayor número de servicios, dentro de los 11 analizados. Sin embargo, parte de los SE brindados dependen de otros servicios proporcionados por el Monte Nativo. La función del Monte Nativo como proveedor de servicios de provisión de agua y de calidad de agua, en la parte alta de la cuenca, es importante y necesaria en la producción de otros servicios, como los relacionados con el aprovisionamiento de madera, ganado y alimentos, que son brindados por el Agroecosistema. Tener en cuenta esta dinámica de la cuenca, plasmada en los mapas de provisión, permite tomar decisiones sobre el uso del agua y del suelo. El presente trabajo aporta la aplicación de una herramienta que puede ayudar en la resolución de problemas, en ser soporte en la toma de decisiones para el ordenamiento territorial, como así también para el uso y manejo de ecosistemas, y en la formación de paisaje.Fil: Teruya, Jorgelina Tsuneko. Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias.
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Lorscher, Christopher. "Novel properties of ferromagnetic p-wave superconductors." Doctoral diss., University of Central Florida, 2014. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/6310.
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This thesis investigates the many extraordinary physical properties of the candidate p-wave ferromagnetic superconductors UCoGe and URhGe, and proposes theoretical predictions for p-wave superconductors yet to be discovered. In particular, we carry out angular dependent quantum field theoretical calculations of the thermodynamic H - T phase diagram known as the upper critical field, or more appropriately for ferromagnetic superconductors the upper critical induction, for various p-wave superconducting order parameter symmetries including: The axial Anderson-Brinkman-Morel(ABM) state, the chiral Scharnberg-Klemm (SK) state, and the completely broken symmetry polar state (CBS), as well as for some other states with partially broken symmetry (PBS) superconducting order parameter symmetries. The most notable contribution of the work presented in this thesis is the application of the Klemm-Clem transformations to analytically calculate the full angular and temperature dependencies of the upper critical field for orthorhombic materials, which may prove to be useful to experimentalists in identifying these exotic states of matter experimentally. Second, this work formulates a double spin-split ellipsoidal Fermi surface (FS) model for ferromagnetic superconductors in the normal state, which introduces a field dependence to the effective mass in one crystallographic direction on the dominant Fermi surface and to the chemical potential, and is subsequently applied to the normal state of URhGe to explain theoretically the anomalous specific heat data of Aoki and Flouquet. Extension of this work to understanding the still elusive reentrant high-field superconducting phase of URhGe and the S-shaped upper critical field curve for external magnetic field parallel to the b-axis direction inUCoGe is discussed. Third, this work also presents theoretical fits to the upper critical field data of Kittika et al. for Sr2RuO4 using the helical p-wave states and including Pauli limiting effects of the three components of the triplet pair-spin fixed to the highly conducting layers by strong spin-orbit coupling.Ph.D.
Doctorate
Physics
Sciences
Physics
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Yan, Tingting. "Effects of delayed drainage on subsidence modeling and parameter estimation." Thesis, Virginia Tech, 2007. http://hdl.handle.net/10919/44308.
Full textAbstract:
The use of delayed drainage in land subsidence modeling greatly complicates model calibration, particularly when the thickness of the fine-grained interbeds varies throughout the modeled region. This thesis documents two separate projects (chapters) related to the use of delayed drainage in groundwater flow and subsidence modeling with parameter estimation. The overall goal of these projects was to better understand how delayed drainage affects accurate parameter estimation and how it is currently affecting the subsidence processes occurring in Las Vegas Valley.
Chapter 1 describes an investigation on the value of subsidence data for groundwater model calibration considering delayed drainage. The calibration results of 13 hydraulic parameters of a synthetic conceptual model evaluated for 24 test cases indicate that (1) the inverse of the square of the observation values is a reasonable method to weight the observations, (2) spatially abundant subsidence data typically produce superior parameter estimates even with observation error under constant and cyclical pumping, (3) when subsidence data are limited and combined with drawdown data, outstanding results are obtained for constant pumping conditions. However, for cyclical pumping with observation errors, the best parameter estimates are achieved when multiple years of seasonal subsidence data are provided. The results provide useful suggestions for real-world calibration problems.
Chapter 2 outlines the development of an updated flow and subsidence model for Las Vegas Valley covering the entire period of development of the basin. The new model includes a subsidence package that takes into account delayed drainage of fine-grained interbeds. Previous models used subsidence packages that assumed instantaneous equilibration of heads across all hydrogeologic units. The new model resulted in an agreement with measured water-level and improved the simulation of land subsidence. The analysis shows that the typical residual subsidence in Las Vegas Valley can be accurately simulated by incorporating delayed drainage in a long-term model. The study also indicates the need for more sophisticated modeling practices that use delayed drainage with parameter estimation processes to accurately calibrate flow and subsidence models.Master of Science
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Ugwu, Sylvester Uche [Verfasser]. "Church and Civil Society in 21st Century Africa : Potentialities and Challenges Regarding Socio-Economic and Political Development with Particular Reference to Nigeria / Sylvester Uche Ugwu." Frankfurt a.M. : Peter Lang GmbH, Internationaler Verlag der Wissenschaften, 2017. http://d-nb.info/1144803012/34.
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Coronado, Horacio Rubén, Peñaloza Maira Sabrina Gutiérrez, Cardozo Yanina Belén Truyols, and Ives Yoel Vela. "La aplicación de herramientas de costos en las actividades desempeñadas por pequeños productores agropecuarios, en la región del Valle de Uco." Bachelor's thesis, Universidad Nacional de Cuyo. Facultad de Ciencias Económicas, 2016. http://bdigital.uncu.edu.ar/7587.
Full textAbstract:
El presente Trabajo de Investigación tiene como objetivo general “La aplicación de herramientas de Costos en las actividades desempeñadas por pequeños productores agrícolas, en la región del Valle de Uco".
Debido a la escasez de recursos con los que cuentan estos productores y la imposibilidad de acceder a conocimientos especializados sobre la gestión de los costos productivos, es necesario, desde una perspectiva de responsabilidad social como estudiantes universitarios comprometidos, enfatizar de modo especial en la colaboración para con este sector económico, con el objetivo de que sigan siendo el principal sostén de la economía regional y no se vean absorbidos por las grandes empresas o productores multinacionales.
Este trabajo analiza los distintos rendimientos y variables que afectan el desenvolvimiento del productor en el sector agrícola de la provincia, y como consecuencia de ello aplicar una herramienta simple y útil para el desarrollo de sus actividades y su sustentabilidad en el tiempo.Fil: Coronado, Horacio Rubén. Universidad Nacional de Cuyo. Facultad de Ciencias Económicas.
Fil: Gutiérrez Peñaloza, Maira Sabrina. Universidad Nacional de Cuyo. Facultad de Ciencias Económicas.
Fil: Truyols Cardozo, Yanina Belén. Universidad Nacional de Cuyo. Facultad de Ciencias Económicas.
Fil: Vela, Ives Yoel. Universidad Nacional de Cuyo. Facultad de Ciencias Económicas.
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Jiménez, Álvarez Luis Gonzalo. "Diseño y Especificación del ocio digital con fines de aprendizaje ODFA Subproblema: Ocio digital formativo en competencias ODFC para la UCE." Doctoral thesis, Universidad de Alicante, 2021. http://hdl.handle.net/10045/115210.
Full textAbstract:
El desarrollo humano en la sociedad digital debe ser integral, una alternativa, es la fusión del ocio formal y los recursos digitales que generan el ocio digital, al añadirle el aprendizaje (individual y colaborativo) se forja el ocio digital con fines de aprendizaje ODFA, de este modelo se desprenden varios subproblemas, uno de ellos es el ocio digital formativo en competencia ODFC y su instancia denominada ocio digital formativo que integra competencias ODFIC, constituyendo en nuevas alternativas para enseñar y aprender. La investigación tiene como objetivos: establecer los fundamentos conceptuales y el estado del arte, establecer la especificación funcional y estructural del ODFA, realizar actividades de diseño del ODFC y el ODFIC, controlar y contribuir a la valorización del ocio digital, analizar los datos estadísticos sobre el ODFA y establecer un plan de acción para la Universidad Central del Ecuador UCE. La metodología como proceso de investigación utilizó el método causal formal MCF y el análisis estadístico descriptivo. Antes de construir un edificio se requiere los planos, igualmente, para desarrollar un software para el ODFA previamente se diseña y especifica el sistema, para ello se aplicó el MCF que permite identificar el problema y darle solución [1]. Se estableció que la conjetura (hipótesis inicial) es: “con el ocio digital es posible obtener conocimiento ubicuo para aprender o crear”. La finalidad es especificar y diseñar sistemas de ocio digital para ayudar al aprendizaje que se motiva porque se quiere sacar provecho docente al ocio digital y porque se quiere buscar estrategias para producir aprendizaje en tiempo libre. Posteriormente, se determinó la especificación funcional, estructural y contextual. Aplicando el modelado, dentro del conjunto de las “actividades en ocio digital” se determinó el modelo ODFA, que es el empleo formativo de sistemas digitales en tiempo libre. Se establecieron los objetivos o “para qué” siguientes: explotar el esfuerzo, el tiempo, el factor de complacencia, los rasgos específicos que tiene el ocio digital y ampliar el desarrollo curricular con aprendizaje ubicuo con fines docentes, uso recreativo de los recursos digitales con aprendizaje, ocio digital incorporado a la teoría de la educación, cubrir competencias curriculares, avanzar en la organización escolar, control y valorización del ocio digital. Dado lo extenso del proyecto ODFA, se resolvieron los tres últimos objetivos a través de los “cómo” o módulos siguientes: ODFC, ODFIC, FODA, rastreando y evaluando la actividad, promoviendo la percepción social sobre el ocio digital, gestionando la trazabilidad de los procesos del ODFC y apoyando académica y económicamente al ocio digital formativo, además, se analiza los “con qué” o los componentes de la solución. Adicionalmente se generan los grafos que indican la funcionalidad del problema y subproblemas. En la parte contextual se responden a las cuestiones: ¿cuándo?, ¿quién?, ¿cuánto?, ¿dónde? ¿a quienes? La aportación científica está en avanzar en la identificación de modelos, potenciar la resolución de problemas y la toma de decisiones en el marco del ODFA, en justificar el ocio como “scholé”, describir los recursos digitales orientados al aprendizaje, en plantear que el ODFA se alinea al “constructivismo conectado” a través del MCF que siendo usado en el diseño y especificación de sistemas también permite investigar conocimiento conocido (aprender) y generar conocimiento nuevo (crear) en forma ubicua. El ODFA involucra a la institución universitaria, docentes, el currículo, las actividades de los discentes (actores principales), el rastreo, la evaluación, el MCF (con el soporte de la App Mayéutica) y la ética. Mientras que el subproblema ODFC como una asignatura plantea potenciar las habilidades y capacidades, el ODFIC como un proyecto integrador de varias disciplinas propone la integración de las competencias: resolución de problemas, colaboración, creación y comunicación. Se concluye que el ODFA no solo plantea la transformación de la estrategia educativa sino que agrega valor reflexivo al proceso de aprendizaje con base a la “escuela digital” y “constructivismo conectado”, en este marco, el subproblema ODFC potencia las competencias gracias a MCF fuera de lo tradicional, fortalece el autoaprendizaje formal dirigido por el docente, porque lo que cuenta es la percepción observacional e intelectual hacia la causalidad a fin de comunicar los resultados, inventos o prototipos con objetividad de forma individual o grupal.
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Radil, Lukáš. "Model akumulace velkých objemů energie." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2008. http://www.nusl.cz/ntk/nusl-217632.
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The purpose of this pursuit is to introduce the reader about the questions of the accumulation of the electric energy and to outline possibilities of its design and what instruments is possible to get it. The other purpose is to inscribe possibilities of today´s attachment of dispersive sources to the net from the sight of the ERU, eventually from the sight of the UCTE. This persuit describes the posibility of the accumulation of adequate dimensions from renewable resources, the modern trends in this area and the prediction of future progress. The two most proper types of the energy accumulation are chosen by the following process with regarding to the optimal resolution of the given questions. The general balance will be ana-lysed by the comparison of their basic parameters. The other point of this pursuit is to try to realize a small model of the accumulation through the hydrogen´s cycle, it comes to that we can develop the efficiency and influence by the help of the electrolyzer and the metalhydride reservoir is realized energy of accumulation . In the conclusion of this pursuit is the appreciation of the whole project with the view of partly economical and especially with the view of the prospective usage into the electric grid
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Šubr, Jiří. "Porovnání RT vlastností 8-bitových a 32-bitových implementací jádra uC/OS-II." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2013. http://www.nusl.cz/ntk/nusl-236389.
Full textAbstract:
This thesis concerns of benchmarking $\mu$C/OS-II systems on different microcontroller architectures. The thesis describes COS-II microcontroller core and possible series of benchmark tests which can be used. Selected tests are implemented and measured properties of microcontrollers with different architecture are compared.
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Van, der Lugt Sanne [Verfasser], Guido [Akademischer Betreuer] Möllering, Adalbert [Gutachter] Wilhelm, and Chibuike [Gutachter] Uche. "Re-evaluating the impact of institutional distance on the location choice and success of foreign Investors : comparing Chinese and Western investors in Africa / Sanne van der Lugt ; Gutachter: Adalbert Wilhelm, Chibuike Uche ; Betreuer: Guido Möllering." Bremen : Staats- und Universitätsbibliothek Bremen, 2018. http://d-nb.info/1186248505/34.
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Lugt, Sanne van der [Verfasser], Guido [Akademischer Betreuer] Möllering, Adalbert [Gutachter] Wilhelm, and Chibuike [Gutachter] Uche. "Re-evaluating the impact of institutional distance on the location choice and success of foreign Investors : comparing Chinese and Western investors in Africa / Sanne van der Lugt ; Gutachter: Adalbert Wilhelm, Chibuike Uche ; Betreuer: Guido Möllering." Bremen : Staats- und Universitätsbibliothek Bremen, 2018. http://d-nb.info/1186248505/34.
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Rojas, Viteri Juan Carlos. "Modelo flipped learning aplicado a la asignatura de sistemas operativos II de la carrera de informática de la UCE: estudio de caso para medir el nivel de motivación y satisfacción tecnológica en el uso de la plataforma Moodle." Doctoral thesis, Universidad de Alicante, 2020. http://hdl.handle.net/10045/114854.
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Arias, Candela Mariel. "Conservación e intercambio de semillas criollas." Bachelor's thesis, Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias, 2018. http://bdigital.uncu.edu.ar/11571.
Full textAbstract:
Las semillas de variedades criollas constituyen reservorios de diversidad biocultural. Esto se debe a que las mismas constituyen una materialización de las características culturales e históricas de las comunidades donde se han desarrollado. Es por ello, que la conservación de semillas cumple un doble propósito: por un lado, permite conservar la diversidad biológica (principalmente la agrobiodiversidad) y por el otro la diversidad cultural asociada a dichas variedades. Con referencia a lo anterior, en el Valle de Uco, Mendoza, Argentina, se realiza desde el año 2015 “La Feria de Intercambio de Semillas y Saberes". La misma representa un espacio de encuentro e intercambio de semillas, plantas, tubérculos y saberes asociados a los mismos, que involucra no solo a la comunidad del Valle de Uco sino también a otras comunidades de la provincia de Mendoza.
A pesar del importante papel que juega la conservación in situ y el intercambio de semillas llevado a cabo por determinados agricultores familiares del Valle de Uco en la conservación de la agrobiodiversidad, la bibliografía sobre cómo es llevada adelante dicha conservación, se presenta en registros aislados, no sistematizados y escasos.
En referencia a lo anterior, el presente trabajo tiene como objetivo general comprender la
contribución de los agricultores familiares, que participan de la Feria de Intercambio de Semillas
del Valle de Uco y residen en dicho lugar, a la conservación de la agrobiodiversidad. Para alcanzar dicho objetivo, en La Feria de Intercambio de Semillas y Saberes, llevada a cabo durante el año 2017, se identificaron 10 agricultores familiares que conservan semillas. Los mismos fueron catalogados como informantes claves (mayor conocimiento y experiencia sobre conservación de semillas) y posteriormente fueron entrevistados.
El análisis de las entrevistas permitió identificar 33 variedades criollas que están siendo conservadas por los agricultores. Así mismo, se identificaron 5 motivos que incentivan a los agricultores a conservar sus semillas, entre los mismos se encuentran: la certeza de que van a germinar; la percepción de que sus semillas darán alimentos más sanos; la necesidad de conservarlas a través del tiempo; para ahorrar dinero y para asegurarse los insumos productivos. Además, se rescataron diversas formas locales de prácticas de conservación de semillas que se han presentado agrupadas en tres categorías: conservación a campo, conservación en sitios adecuados e intercambio de semillas.
Finalmente y producto de una comparación entre los géneros y variedades criollas conservadas por el Banco de Germoplasma del INTA de La Consulta por los agricultores, se observa que de los 17 géneros conservados en el Banco solo 6 son conservados por los agricultores. En tanto que de los 12 géneros conservados por los agricultores 6 son conservados por el Banco de Germoplasma. Por su parte, de las 27 variedades hortícolas criollas conservadas por los agricultores, solo 9 son conservadas por el Banco. Estos resultados ponen de manifiesto la necesidad de complementariedad entre ambos métodos.
Los resultados obtenidos demuestran la importancia de la contribución de los agricultores familiares del Valle de Uco a la conservación de la agrobiodiversidad local mediante la conservación de semillas criollas. Asimismo, los resultados, exponen la necesidad de incrementar las medidas tendientes al reconocimiento de los agricultores como pilares fundamentales de la conservación de la agrobiodiversidad. Además, dichas medidas deberían apuntar a fortalecer el trabajo conjunto entre el INTA u otras instituciones y los agricultores familiares en pos de la conservación de la agrobiodiversidad criolla.Fil: Arias, Candela Mariel. Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias.
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Gaona, Garcia Jaime. "Groundwater-stream water interactions: point and distributed measurements and innovative upscaling technologies." Doctoral thesis, Università degli studi di Trento, 2019. http://hdl.handle.net/11572/242544.
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The need to consider groundwater and surface water as a single resource has fostered the interest of the scientific community on the interactions between surface water and groundwater. The region below and alongside rivers where surface hydrology and subsurface hydrology concur is the hyporheic zone. This is the region where water exchange determines many biogeochemical and ecological processes of great impact on the functioning of rivers. However, the complex processes taking place in the hyporheic zone require a multidisciplinary approach.
The combination of innovative point and distributed techniques originally developed in separated disciplines is of great advantage for the indirect identification of water exchange in the hyporheic zone. Distributed techniques using temperature as a tracer such as fiber-optic distributed temperature sensing can identify the different components of groundwater-surface water interactions based on their spatial and temporal thermal patterns at the sediment-water interface. In particular, groundwater, interflow discharge and local hyporheic exchange flows can be differentiated based on the distinct size, duration and sign of the temperature anomalies. The scale range and resolution of fiber-optic distributed temperature sensing are well complemented by geophysics providing subsurface structures with a similar resolution and scale. Thus, the use of fiber-optic distributed temperature sensing to trace flux patterns supported by the exploration of subsurface structures with geophysics enables spatial and temporal investigation of groundwater-surface water interactions with an unprecedented level of accuracy and resolution.
In contrast to the aforementioned methods that can be used for pattern identification at the interface, other methods such as point techniques are required to quantify hyporheic exchange fluxes. In the present PhD thesis, point methods based on hydraulic gradients and thermal profiles are used to quantify hyporheic exchange flows. However, both methods are one-dimensional methods and assume that only vertical flow occurs while the reality is much more complex. The study evaluates the accuracy of the available methods and the factors that impact their reliability. The applied methods allow not only to quantify hyporheic exchange flows but they are also the basis for an interpretation of the sediment layering in the hyporheic zone.
For upscaling of the previous results three-dimensional modelling of flow and heat transport in the hyporheic zone combines pattern identification and quantification of fluxes into a single framework. Modelling can evaluate the influence of factors governing groundwater-surface water interactions as well as assess the impact of multiple aspects of model design and calibration of high impact on the reliability of the simulations. But more importantly, this modelling approach enables accurate estimation of water exchange at any location of the domain with unparalleled resolution. Despite the challenges in 3D modelling of the hyporheic zone and in the integration of point and distributed data in models, the benefits should encourage the hyporheic community to adopt an integrative approach comprising from the measurement to the upscaling of hyporheic processes.
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Lu, Po-Hung, and 呂柏鋐. "The Business Model of UCOM IT Training Center." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/7wyktv.
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碩士國立臺灣科技大學
資訊管理系
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The Professional Technical Certification and Training Industry has been flourished for years in tandem with the advancement in information technology and knowledge transfer. Professional training centers have provided high quality and to-the-point expertise advices for their customers. Apparently, professional training centers not only speeds up their customers’ knowledge but also help their customers to acquire the professional certifications. SYSTEX Information - UCOM Training Centre has enjoyed its great success in the field of information technology professional trainings and has grabbed over 50 percent of Taiwan’s IT training market. To discuss the SYSTEX Information - UCOM Training Centre’s great achievement, several theories have been employed such as resource-based view, modularity, proactive strategy, and the concept of organizational ambidexterity. The case suggests that the case company develops several unique resources such as company’s customer relations, brand resources and environmental resources; through the modularity of its core competences, the case company has enhanced its resource utilization. Also, the proactive management and organizational ambidexterity has enabled the firm to agile adapt to market needs.
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Melo, Nilsa Santos. "UCO-PEEKING: sistema IoT para automatização da recolha de óleos alimentares usados." Master's thesis, 2022. http://hdl.handle.net/10284/10802.
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Os Óleos Alimentares Usados OAU, vulgarmente resultantes dos processos de confeção culinária, têm efeitos nocivos para a saúde e para o ambiente em geral. No entanto estes resíduos podem ser reutilizados como biocombustíveis, motivando por isso o surgimento de soluções de recolha, particularmente os provenientes de contextos domésticos, uma vez que podem ser reciclados em maior escala.
Existem atualmente redes de pontos de recolha a nível nacional RENO, contudo, a grande maioria do óleo alimentar usado, produzido em ambiente doméstico, ainda não é recolhido, continuando portanto a ser descartado indevidamente e sem entrar nos processos de reciclagem. Adicionalmente, nem todos os depósitos que entram nas redes de recolha são totalmente recicláveis uma vez que os utilizadores depositam por vezes outros líquidos (e.g. água, óleos usados de carro) que não podem entrar nos processos de reciclagem dos OAU.
Com vista a melhorar a eficiência e a taxa de utilização das redes de recolha existentes, propõe-se neste trabalho um sistema IoT que permite automatizar a classificação dos depósitos de óleo alimentar usado, bem como a sua associação a utilizadores registados, aos quais poderão desta forma ser atribuídas bonificações sempre que é detetado um depósito fidedigno.
Neste projeto foram portanto estudadas formas de automatizar a recolha e identificação de OAU, por forma a distinguir depósitos fraudulentos. Pretendeuse em concreto conseguir distinguir OAU de outros líquidos vulgarmente encontrados em depósitos nas redes de recolha, tais como, óleo de automóvel usado e água. Mais concretamente, foram estudados, analisados e combinados vários tipos de sensores que pudessem ser utilizados para diferenciar de forma automática os tipos de líquidos depositados nos oleões de recolha.
Com base nesses sensores e recorrendo à fusão de informação proveniente das várias fontes, foi possível obter uma forma automática de diferenciação dos líquidos depositados. A integração desta solução numa arquitetura IoT permite então automatizar e melhorar o processo de recolha e classificação de forma distribuída e global. Concomitantemente, associado à simplificação e facilidade de utilização da rede de recolha, desenvolveu-se um sistema de gestão e atribuição de benefícios com o objetivo de sensibilizar a população para a reciclagem, e ainda facilitar e incrementar a sua utilização com base num programa de atribuição de pontos diretamente associado aos depósitos domésticos fidedignos de OAU.Used cooking oils OCU, commonly resulting from cooking processes, have harmful effects on health and the environment in general. However, these residues can be reused as biofuels, thus motivating the emergence of collection solutions, particularly those from domestic contexts, since they can be recycled on a larger scale. There are currently networks of collection points nationwide RENO, however, the vast majority of used cooking oil, produced in the domestic environment, is still not collected, and therefore continues to be improperly disposed without entering the recycling processes. Additionally, not all deposits entering the collection networks are fully recyclable as users sometimes deposit other liquids (e.g. water, used car oils) that cannot enter the OCU recycling processes. In order to improving the efficiency and utilization rate of the existing collection networks, an IoT system is proposed in this work allowing to automate the classification of used cooking oil disposals, as well as their association with registered users, who can benefit from bonuses whenever a trustworthy deposit is detected. In this project, ways were studied to automate the collection and classification of OCU, in order to distinguish fraudulent deposits. The aim was specifically to distinguish OCU from other liquids commonly found in disposals in the OCU collection networks, such as used car oil and water. More specifically, various types of sensors that could be used to automatically differentiate the types of liquid deposited in the collection oils were studied, analyzed and combined. Based on these sensors and using the fusion of information from various sources, it was possible to obtain an automatic way of differentiating the deposited liquids. The integration of this solution in an IoT architecture allows then to automate and improve the collection and classification process in a distributed and global way. At the same time, associated with the simplification and ease of use of the collection network, a management and benefit allocation system was developed with the aim of raising awareness among the population about recycling, and also facilitating and increasing its use based on an allocation program of points directly associated with the trusted domestic deposits of OCU.
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Nwandu, McDonald Kelechi. "Akọ na Uche (Wisdom and Justifiability) of Preemptive-strike in Self-defense and Alternative Conflict Resolutions." Doctoral thesis, 2012. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-94846.
Full textAbstract:
The “Akọ na Uche” (Wisdom and Justifiability) of Preemptive-strike in Self-defense and Alternative Conflict Resolutions is an ethical examine on man’s inherent right of self-defense, not only as a right that is innate, but also as an individual’s or a nation’s right enshrined in, and guaranteed by the Charter provisions of the United Nations. Stemming from the painful experience of the First and Second World Wars, nations wishing never again to engage one another in such full scale wars of destruction, met in San Francisco, California, accepted the formation of a new organization, the United Nations, to replace the League of Nations considered as ineffectual. The participating nations articulated a set of guiding principles in the form of rules, rights and responsibilities endorsed by all the early member-nations on June 26, 1945, but effective from October 24, same year. This is the birth of the United Nations Charter. With the endorsement of the Charter, all member-nations assumed the responsibility of making the world a better place, peaceful and secure for humanity. They vowed never again to engage in unethical wars, they accepted to respect and foster human rights, to fight poverty, to spread democracy and to promote more healthy and robust international relations through a more vibrant cooperation and aggressive diplomacy. The Charter also reaffirmed the intrinsic right of self-defense of the victim of an armed attack, which sometimes has been utilized as well as exploitedDas „Ako na Uche“ - die Weisheit und Vertretbarkeit - eines präemptiven Schlags in der Selbstverteidigung und der alternativen Konfliktlösung ist eine ethische Prüfung sowohl auf ein angeborenes Recht auf Selbstverteidigung des Menschen als auch auf die Bewahrung und Garantie eines individuellen Rechts, aber auch einer ganzen Nation, durch die Bestimmungen der Charta der Vereinten Nationen gewährleistet. Ausgehend von der schmerzhaften Erfahrung des Ersten und Zweiten Weltkriegs, wollen sich die Nationen nie wieder gegenseitig in solchen intensiven Kriegen der Zerstörung angreifen. Die Nationen trafen sich in San Francisco, Kalifornien und akzeptierten die Gründung einer neuen Organisation, die Vereinten Nationen, um den Völkerbund, der als unwirksam betrachtet wurde, zu ersetzen. Die teilnehmenden Nationen artikulierten eine Reihe von Leitlinien in Form von Regeln, Rechten und Pflichten, die von allen früheren Mitglied-Nationen am 26. Juni 1945 gebilligt, aber erst ab 24. Oktober desselben Jahres wirksam wurden. Dies ist die Geburtsstunde der Charta der Vereinten Nationen. Mit der Befürwortung der Charta, übernehmen alle Mitgliedsländer die Verantwortung, die Welt zu einem besseren, friedlicheren und sichereren Ort für die Menschheit zu machen. Sie schworen, nie wieder skrupellose Kriege zu führen, sie akzeptierten Menschenrechte zu respektieren und zu unterstützen, gegen Armut zu kämpfen, die Demokratie zu verbreiten und mehr gesunde und stabile internationale Beziehungen durch eine dynamischere Zusammenarbeit und offensive Diplomatie voranzutreiben. Die Charta bekräftigt auch das wesentliche Recht der Selbstverteidigung des Opfers eines bewaffneten Angriffs, das manchmal sowohl benutzt als auch ausgenutzt wurde
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Gomes, Luís André Ribeiro Stahli. "Pilot-scale unit for biodiesel production: impact of UCO quality and properties on process yield." Master's thesis, 2018. http://hdl.handle.net/10400.13/2230.
Full textAbstract:
Several alternative feedstocks have been tested for biodiesel production. As feedstock can represent up to 80% of the operation costs, used cooking oil (UCO) has been widely chosen. The UCO’s price is not the only advantage. Using waste as a raw material is also environmental friendly.
In Madeira Island, there is only one pilot unit dedicated to biodiesel production, and it is located at the company Grupo Sousa / Metal Lobos Lda. in Industrial Free Zone of Madeira. This unit is designed to process two 1000L sets every three days through homogeneous alkaline transesterification in the batch regime, using methanol as a reactant, sodium methoxide as a catalyst, and UCO as feedstock. This raw material is collected in several commercial establishments such as hotels and restaurants. Its proper functionality could bring economic and environmental value to the company and Madeira Island by lowering exhaust emissions and fuel costs.
The purpose of the present work is: (i) Test the pilot unit for possible operational failures and optimization possibilities, (ii) test the establishment of biodiesel production using UCO collected in the region, (iii) analyze how feedstock properties can influence transesterification yields
Several laboratory tests (transesterifications) were performed to acquire a deeper understanding of the reaction behavior and variables before starting the pilot unit tests. On the pilot unit, four tests were performed using a minimum feedstock volume of 500L of UCO.
Biodiesel production yields in the pilot unit varied from 78.52 to 90.37% (w/w). The lowest yields were the ones obtained using UCO with higher acidity values and lower alcohol to oil molar ratio in the reaction (biodiesel with purity of 96.3% (w/w) was obtained with UCO with 9.8% free fatty acids (w/w) and alcohol to oil molar ratio of 7:1). From the evaluation of the transesterification yields, it was possible to conclude that in this pilot unit the influence of the feedstock’s acidity is not so significant, but, it is of utmost importance to further analyze the impact of the impurities on the glycerol quality, as this may determine the economic viability of the whole process.
It was concluded that the pilot unit was functional for biodiesel production, but, due to the feedstock properties variability, optimization should be taken into consideration. Improving both process and procedures such as UCO collection and storage could raise the unit’s yield.Várias matérias-primas têm sido testadas para a produção de biodiesel. Como a matéria-prima pode representar ate 80% do custo operacional, os óleos alimentares usados (OAU) têm sido uma escolha frequente. O preço dos OAU não é a única vantagem. O facto de usarmos um resíduo como matéria-prima é também uma boa escolha do ponto de vista ambiental. Na Ilha da Madeira existe apenas uma unidade piloto dedicada à produção de biodiesel e está situada na empresa Grupo Sousa / Metal Lobos Lda. da zona franca da Madeira. Esta unidade está desenhada para processar dois sets de 1000L em cada três dias através de transesterificação alcalina homogénea em regime de lotes, usando metanol como reagente, metóxido de sódio como catalisador e OAU como matéria prima. Os óleos são recolhidos em vários estabelecimentos comercias da região tal como hotéis e restaurantes. O seu bom funcionamento poderá trazer valor ambiental e económico tanto para a empresa como para a Ilha da Madeira, baixando o nível de emissões de escape e os custos com combustíveis. Os objetivos deste trabalho são: (i) testar a unidade piloto para possíveis falhas de operação assim como para oportunidades de otimização, (ii) testar a implementação de produção de biodiesel utilizando OAU recolhidos na região da Ilha da Madeira, (iii) analisar de que modo as propriedades da matéria-prima influenciam o rendimento da reação de transesterificação. Foram realizados vários ensaios laboratoriais (transesterificações) de forma a adquirir um conhecimento mais aprofundado do comportamento e varáveis da reação antes de passar aos testes na unidade piloto. Nesta última foram realizados 4 testes processando sempre mais de 500L de OAU. Os rendimentos de produção de biodiesel na instalação variaram entre 78,52 e 90,37% (w/w), sendo que o rendimento menor foi obtido como OAU de maior valor de acidez e com uma menor razão molar álcool/óleo na reação (foi obtido biodiesel com pureza de 96,3% (w/w) usando OAU de valor de acidez 9,8% ácidos gordos livres (w/w) e razão molar álcool/óleo de 7:1). Avaliando os rendimentos de transesterificação, foi possível concluir que a influência da acidez da matéria-prima para este parâmetro não é significativa. No entanto, é importante avaliar o impacto das impurezas e propriedades da matéria prima na qualidade do glicerol produzido pois esta poderá determinar a viabilidade económica do processo. Conclui-se que a unidade piloto é funcional para a produção de biodiesel, no entanto, devido essencialmente à variabilidade da matéria prima, sugere-se uma otimização. Melhorando o processo e alguns procedimentos tais como a recolha e conservação dos OAU, talvez se possa alcançar um aumento do rendimento da unidade.
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Pospíšil, Jiří. "Elektronové vlastnosti a struktura vybraných vzácně zeminných a uranových sloučenin: vliv nečistot." Doctoral thesis, 2011. http://www.nusl.cz/ntk/nusl-299643.
Full textAbstract:
Title: Electronic properties and structure of selected rare earth and uranium compounds; influence of impurities Author: Jiří Pospíšil Abstract: This thesis is devoted to studies of influence of impurities and/or chemical varieties on magnetic and superconducting properties of selected metallic materials containing rare earth and uranium. The research generally consisted of the defined preparation of studied materials, detailed composition and structure characterisation, experiments focussed on determination of mutually related magnetic, transport and thermal properties followed by data analysis of relations between material composition/quality and material properties. The technology phase was carried out in two ways - 1) preparation of the best pure materials as possible and 2) controlled doping of pure materials. Three main study cases have been chosen: SmPd2Al3 - the representative of the complex magnetism of the Sm3+ ion, the so far unexplored superconductor YPd2Al3 were selected as the RE materials candidates and the controversial ferromagnetic superconductor UCoGe. The key ingredient of the initial technology phase was the refining the commercially available best element metals to the laboratory best achievable purity grade by the unique Solid State Electrotransport (SSE) method. SSE has been also...
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Crawford, Nicholas Geoffrey. "Genomic analysis of macro- and micro-evolution in the reptilia." Thesis, 2013. https://hdl.handle.net/2144/15658.
Full textAbstract:
Recent advances in high-throughput, genomic sequencing allow unprecedented insight into the evolution of biodiversity. Chapter 1 of this thesis is a phylogenetic study of 1,145 sequenced loci, isolated using a novel high-throughput sequence capture methodology to address the phylogenetic position of turtles within tetrapods. The results reported here unambiguously place turtles as sister to archosaurs and resolve this long-standing question.
Chapter 2 investigates the genetic basis of colorful pigmentation in the Green anole (Anolis carolinensis) by sequencing complete transcriptomes from the green dorsal, white ventral and pink dewlap skin. Anoles comprise an adaptive radiation of more than 400 species and color plays a central role in their ecology and evolution, but little is known about the genetic basis of colorful pigmentation in any vertebrate. This study identified 1,719 differentially expressed genes among the three differently colored tissues. Twenty-three of these genes are involved in melanin, pteridine, and carotenoid pigmentation pathways that contribute to the coloration of anole skin. Identifying candidate genes for colorful pigmentation is a significant advance that opens the field for comparative analysis in other taxa.
To determine if the genes identified in Chapter 2 are involved in population divergence and speciation, Chapter 3 investigates the complete genomes of twenty individuals from two closely related subspecies of Anolis marmoratus. While the two subspecies differ markedly in pigmentation, this study found few genetic differences between populations except in five regions of the genome, which together contained 447 genes. Of these genes, only two, melanophilin (mlph) and 'cluster of differentiation 36' (cd36), are associated with pigmentation. The intersection of the genes identified in Chapter 2 and Chapter 3 includes both cd36 and mlph, suggesting that both are involved in divergence of coloration. Cd36 is of particular interest because it regulates the uptake of carotenoid pigments and is an important candidate gene contributing to carotenoid pigmentation.
Together, this research demonstrates the power of genomic approaches to address fundamental questions in systematics, micro-evolution, and speciation. The findings bolster the emerging field of phylogenomics and broadly impact future research into the genetic basis of coloration in vertebrates.
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Sobral, Pedro Correia Lima. "Análise da influência das técnicas de purificação na qualidade final do biodiesel e viabilidade de implementação de uma unidade industrial." Master's thesis, 2018. http://hdl.handle.net/10362/65245.
Full textAbstract:
O objetivo deste trabalho é determinar qual o processo de separação mais indicado para purificar o biodiesel como produto acabado, com foco especial na maior incorporação de UCOs na produção. Para além disso, pretende-se verificar qual a viabilidade da implementação de uma unidade industrial do processo selecionado.
De modo a atingir os objetivos pretendidos foram: Selecionados parâmetros que se consideraram críticos na qualidade final do biodiesel; estudados os impactos que cada um dos processos de separação teriam nos parâmetros críticos; realizados ensaios laboratoriais e uma simulação computacional da unidade; estabelecidos contactos com licenciadores de forma a estimar o investimento e debater questões técnicas do processo; e analisados 3 cenários de avaliação económica, variando-se entre eles: Taxa de ocupação, tipo de matérias-primas utilizadas e formulações de matérias-primas de acordo com as diferentes épocas do ano.
Concluiu-se que o processo de purificação mais indicado seria a destilação, sendo que os testes laboratoriais permitiram verificar um aumento de 5% no teor de FAME e nos parâmetros FBT, teor de enxofre, teor de água e teor de monoglicéridos houveram reduções de 90%, 59%, 61% e 55%, respetivamente.
Apenas um dos cenários se mostrou economicamente viável, obtendo-se um VAL de 3,8 M€, com um tempo de recuperação de capital de 36 meses.
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Paz, Zanini Raúl Eduardo. "Sitio web para la enseñanza del análisis elemental de funciones y trazado de curvas para estudiantes de la Facultad de Matemática Aplicada - UCSE." Master's thesis, 2015. http://hdl.handle.net/11086/2717.
Full textAbstract:
Trabajo Final (Especialización en Tecnologías Multimedia para Desarrollos Educativos)--UNC- Facultad de Ciencias Agropecuarias, 2015.El objetivo general de este trabajo consistió en desarrollar una propuesta pedagógica-didáctica con el uso de nuevas Tecnologías de la Información y la Comunicación, vinculada a la enseñanza del concepto de función y el trazado de curvas. En un primer acercamiento, se indagó sobre la existencia de sitios similares y fundamentos de la potencialidad que los nuevos software ofrecen para el proceso de enseñanza, particularmente de la enseñanza de conceptos matemáticos a estudiantes ingresantes del nivel universitario. En su desarrollo se mencionan las razones que dan sustento a las potencialidades que los recursos tecnológicos ofrecen y en particular el programa GeoGebra que fue el elegido como mediador tecnológico de la propuesta. Tales razones se aplican, específicamente a la educación matemática universitaria.