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Aziz, Abdul. "Empat Model Aproksimasi Binomial Harga Saham Model black-Scholes." CAUCHY 1, no. 1 (November 15, 2009): 15. http://dx.doi.org/10.18860/ca.v1i1.1702.
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Kami akan menyajikan empat bentuk nilai parameter-parameter u, d, dan p dalam model Binomial harga saham, yang dihasilkan dengan menggunakan penyamaan ekspektasi dan variansi model diskrit dengan kontinu. Metode pertama menggunakan asumsi u . d = 1, yang mana metode ini dapat menghasilkan tiga bentuk solusi untuk parameter-parameter u, d, dan p dalam model Binomial harga saham. Metode kedua menggunakan asumsi p = 0,5. Dari kedua metode ini ternyata dapat dihasilkan empat bentuk solusi u, d, dan p yang berbeda dan akan dibandingkan hasilnya dalam pendekatan nilai option dalam model Binomial dengan model Black-Scholes.
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Rastovski, Dražen. "Model rada - čimbenik uspješnosti poduke plivanja." Život i škola 65, no. 1-2 (December 23, 2019): 57–71. http://dx.doi.org/10.32903/zs.65.1-2.4.
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S ciljem utvrđivanja učinkovitosti pojedinih modela poduke neplivača i njihove usporedbe, testirano je 201 dijete populacije između 9 i 11 godina. Uzorak je podijeljen na dva subuzorka, gdje su djeca učila plivati prema istom programu, ali u različitim modelima rada. Prvi je model bio model poduke neplivača u sklopu ljetovanja i to u trajanju od 14 dana, dok je drugi model proveden u okviru škole u prirodi ali u šest dana. Za utvrđivanje učinkovitosti navedenih modela korišten je statistički programski paket STATISTICA verzija 6.0 (StatSoft Inc., Tulsa, OK, SAD). Normalnost distribucije pojedinih varijabli provjerena je Kolmogorov-Smirnov testom te je utvrđeno da ne slijede istu. Za usporedbu napretka u skupinama korišten je Wilcoxon Matched Pairs Test, a za usporedbu među skupinama Mann-Whitney U Test (za usporedbu inicijalnog i finalnog mjerenja te razlike između finalnog i inicijalnog mjerenja). Kao statistički značajna korištena je vrijednost P<0,05. Rezultati dobiveni provedenim istraživanjem pokazali su da oba modela pokazuju dobre rezultate i prigodni su za poduku neplivača. Prednost dajemo modelu 1. odnosno poduci neplivača u okviru ljetovanja. Model 2. poduke neplivača u okviru škole u prirodi radi se u šest dana i očito mu nedostaje vremenskog prostora za još kvalitetniju provedbu. Kako je riječ o programima koji se provode u svim sredinama, neobično je bilo važno utvrditi učinkovitost programa te detektirati uspješnosti pojedinih modela.
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Koikegami, Shigeru, and Takashi Yanagisawa. "Superconductivity of the 2D d–p model with a small U." Journal of Physics and Chemistry of Solids 63, no. 6-8 (June 2002): 1373–77. http://dx.doi.org/10.1016/s0022-3697(02)00035-5.
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Yang, Jing, Xuemei Deng, and Qunyi Bie. "Global regularity for the tropical climate model with fractional diffusion." AIMS Mathematics 6, no. 10 (2021): 10369–82. http://dx.doi.org/10.3934/math.2021601.
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<abstract><p>In this paper, we investigate the following tropical climate model with fractional diffusion</p> <p><disp-formula> <label/> <tex-math id="FE1"> \begin{document}$ \begin{eqnarray} \left\{\begin{array}{ll} u_t+u\cdot\nabla u+\nabla p+\Lambda^{2\alpha}u+{\rm div}(v\otimes v) = 0,\\[1ex] v_t+u\cdot\nabla v+\nabla\theta+\Lambda^{2\beta}v+v\cdot\nabla u = 0,\\[1ex] \theta_t+u\cdot\nabla\theta+\Lambda^{2\gamma}\theta+{\rm div} v = 0,\\[1ex] {\rm div} u = 0,\\[1ex] ( u, v, \theta)(x,0) = ( u_0, v_0, \theta_0), \end{array} \right. \end{eqnarray} $\end{document} </tex-math> </disp-formula></p> <p>where $ (u_0, v_0, \theta_0) \in H^s(R^n) $ with $ s\geq 1, n\geq 3 $ and $ {\rm div} u_0 = 0 $. When the nonnegative constants $ \alpha, \beta $ and $ \gamma $ satisfy $ \alpha\geq\frac{1}{2}+\frac{n}{4}, \ \alpha+\beta\geq 1+\frac{n}{2}, \ \alpha+\gamma\geq1+\frac{n}{2} $, by using the energy methods, we obtain the global existence and uniqueness of solution for the system. In the special case $ \theta = 0 $, we could obtain the global solution provide that $ \alpha\geq\frac{1}{2}+\frac{n}{4}, \alpha+\beta\geq1+\frac{n}{2} $ and $ (u_0, v_0)\in H^s(s\geq1) $, which generalizes the existing result.</p></abstract>
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Lima-Santos, A. "On the $$\mathcal{{U}}_{q}[osp(1|2)]$$ U q [ o s p ( 1 | 2 ) ] Temperley–Lieb Model." Journal of Statistical Physics 165, no. 5 (November 5, 2016): 953–69. http://dx.doi.org/10.1007/s10955-016-1648-z.
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Hansen, Blake, Tao Liu, Lauri Bazerman, Mari-Lynn Drainoni, Fizza S. Gillani, Edward Cachay, Katerina Christopoulos, et al. "994. Risk for Viral Rebound in the Era of U=U; A CNICS Analysis." Open Forum Infectious Diseases 7, Supplement_1 (October 1, 2020): S525—S526. http://dx.doi.org/10.1093/ofid/ofaa439.1180.
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Abstract Background The “Undetectable equals Untransmittable (U=U)” HIV prevention campaign is a cornerstone of HIV prevention. However, there are few recommendations to guide patients and providers in U=U implementation and limited data on risk factors for viral rebound among persons eligible for U=U. Methods We conducted a retrospective multi-center study using data from the CNICS HIV research network to identify risk factors for viral rebound among persons with established viral suppression [two viral loads (VL) and all VLs of < 200 copies/ul within a one-year period (U=U eligible)]. Demographics, patient-reported outcomes, and longitudinal clinical data from 21,359 persons with HIV were analyzed. To include missing data in the analysis, they were treated as a separate category. The primary outcome of viral rebound was defined as any VL > 200 copies/ul within two years after U=U eligibility. A univariable logistic regression model was conducted to identify predictors of viral rebound. Significant variables (p< 0.05) were included in a multivariable logistic regression model. Predictive values of individual variables were captured by adjusted odds ratios (aORs). Results From 2011-2019, 12,150 patients met criteria for U=U eligibility and had two years of follow up data. The median age was 46 (IQR: 38-53); 68% male; 51% were white, 39% black. 1544 (13%) experienced viral rebound during follow-up. Forest plot summaries of univariable and multivariable logistic regression models are in Figures 1&2. In multivariable analysis, Black race (aOR=1.56, p< 0.001); MSM-IDU risk (aOR=1.38, p=0.006); lower QoL score (aOR=1.49, p=0.005); poorer ART adherence (aOR=1.84, p< 0.001); duration of lifetime ART [aOR=1.47 (10+yrs), = 1.37 (5-10 yrs); and = 1.28 (2-5 yrs), p< 0.001]; use of InSTIs after eligibility (aOR=1.60, p< 0.001); current smoker (aOR=1.49, p< 0.001), current amphetamine (aOR=1.83, p< 0.001) or cocaine use (aOR=1.46, p=0.012), were associated with viral rebound. In both analyses, older age was protective against viral rebound. Figure 1. Summary of Univariate Logistic Regression Model Figure 2. Summary of Multivariable Logistic Regression Model Conclusion We identified multiple risk factors for viral rebound among PWH with viral suppression. Further research is needed to identify synergistic risk factors that increase probability of viral rebound to inform optimal implementation of U=U. Disclosures Edward Cachay, MD, MAS, Gilead (Consultant, Grant/Research Support)Merck Sciences (Grant/Research Support) Heidi Crane, MD, MPH, ViiV (Grant/Research Support) Benigno Rodriguez, MD, Gilead (Speaker’s Bureau)ViiV (Speaker’s Bureau)
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Kuo, John S., Cheng Yu, Steven L. Giannotta, Zbigniew Petrovich, and Michael L. J. Apuzzo. "The Leksell Gamma Knife Model U versus Model C: A Quantitative Comparison of Radiosurgical Treatment Parameters." Neurosurgery 55, no. 1 (July 1, 2004): 168–73. http://dx.doi.org/10.1227/01.neu.0000126880.33125.e6.
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Abstract OBJECTIVE: We present a quantitative comparison of radiosurgery treatments for cavernous sinus tumors using the Leksell gamma knife Model U versus the Model C with automatic positioning system (APS) (Elekta Instruments, Norcross, GA). METHODS: At our medical center from August 1994 through May 2000, the Model U was used to treat 96 patients (37 men [39%] and 59 women [61%]; median age, 54.5 yr) with benign cavernous sinus tumors: 43 meningiomas (45%), 48 pituitary tumors (50%), and 5 others (5%). From June 2000 through April 2002, the Model C with APS treated 45 patients (20 men [44%] and 25 women [56%]; median age, 51.4 yr) with 15 meningiomas (33%), 29 pituitary tumors (65%), and 1 schwannoma (2%). The two groups had similar treated tumor volumes (Model U mean, 4.3 cm3; Model C mean, 4.2 cm3), equivalent tumor distances from critical structures (optic nerve, chiasm, and pons), comparable distributions in Sekhar tumor grades, and the same median prescribed dose of 15 Gy to the 50% isodose line at the tumor periphery. All planning and treatments were performed by the same radiosurgery team to minimize dosage to adjacent critical tissues and to optimize conformity index. RESULTS: Analysis of multiple treatment parameters showed that the Model C plans were superior. Model C treatments had an improved conformity index (Model U mean, 1.7; Model C mean, 1.6; P < 0.02) and a lower underdosed tumor volume (Model U mean, 0.4 cm3; Model C mean, 0.1 cm3; P < 0.004). The total treated volume and the excess treated volume were similar. The Model C group had a reduction in optic chiasm dose (Model C mean dose, 3.8 Gy; Model U mean dose, 5.3 Gy; P < 0.0001). The average number of isocenters was slightly higher for the Model C group (6.7 versus 6 for the Model U), but with a lower mean number of collimator sizes (1 versus 2 for the Model U). Model C plans required a mean of 93 fewer plugs per treatment, thus contributing to an estimated 67.6 minutes saved per treatment session. CONCLUSION: Comparison of radiosurgery treatments using the Leksell gamma knife Model U versus the Model C with APS was performed by quantitative analysis of treatment parameters on a cohort of benign cavernous sinus tumors. Treatment plans using the Model C resulted in better tumor coverage (improved conformity, less underdosed tumor volume) and decreased optic chiasm dose. An estimated average of 1 hour was saved per treatment when using the Model C with APS.
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Dȩbicki, Krzysztof, Lanpeng Ji, and Tomasz Rolski. "Logarithmic Asymptotics for Probability of Component-Wise Ruin in a Two-Dimensional Brownian Model." Risks 7, no. 3 (August 1, 2019): 83. http://dx.doi.org/10.3390/risks7030083.
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We consider a two-dimensional ruin problem where the surplus process of business lines is modelled by a two-dimensional correlated Brownian motion with drift. We study the ruin function P ( u ) for the component-wise ruin (that is both business lines are ruined in an infinite-time horizon), where u is the same initial capital for each line. We measure the goodness of the business by analysing the adjustment coefficient, that is the limit of - ln P ( u ) / u as u tends to infinity, which depends essentially on the correlation ρ of the two surplus processes. In order to work out the adjustment coefficient we solve a two-layer optimization problem.
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Malozovsky, Y. M., and J. D. Fan. "Pseudogap and Unconventional Pairing in the Hubbard Model." International Journal of Modern Physics B 12, no. 29n31 (December 20, 1998): 2939–45. http://dx.doi.org/10.1142/s0217979298001812.
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The attractive (U < 0) and repulsive (U > 0) Hubbard models have been studied using the Fermi liquid perturbation approach. The attractive Hubbard model (U < 0) is an adequate model for 3 He , an incompressible and strongly paramagnetic liquid [Formula: see text], [Formula: see text] for |U|N F = 0.9) with a pseudogap in the charge response. A pairing instability and superfluidity for U < 0 exists in the spin channel only: spin-triplet with l = 0, or spin-singlet with l = 1 (p-wave orbital state j = s + l = 1), where l is the orbital momentum of a pair. The repulsive Hubbard model (U > 0) represents a highly compressible and nearly antiferromagnetic liquid [Formula: see text], [Formula: see text] for UN F = 0.9) with a pseudogap in the spin response. However, for U > 0 a pairing instability and superconductivity exist in the charge channel only: spin-singlet with l = 0 (s-wave), or with l = 2 (d-wave) in the case of an anisotropic Fermi surface.
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Deng, Yinbin, Shuangjie Peng, and Jixiu Wang. "Nodal Solutions for a Quasilinear Elliptic Equation Involving the p-Laplacian and Critical Exponents." Advanced Nonlinear Studies 18, no. 1 (February 1, 2018): 17–40. http://dx.doi.org/10.1515/ans-2017-6022.
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AbstractThis paper is concerned with the following type of quasilinear elliptic equations in{\mathbb{R}^{N}}involving thep-Laplacian and critical growth:-\Delta_{p}u+V(|x|)|u|^{p-2}u-\Delta_{p}(|u|^{2})u=\lambda|u|^{q-2}u+|u|^{2p^{% *}-2}u,which arises as a model in mathematical physics, where{2<p<N},{p^{*}=\frac{Np}{N-p}}. For any given integer{k\geq 0}, by using change of variables and minimization arguments, we obtain, under some additional assumptions onpandq, a radial sign-changing nodal solution with{k+1}nodal domains. Since the critical exponent appears and the lower order term (obtained by a transformation) may change sign, we shall use delicate arguments.
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Shin, Seung-Ho, Jung-Hwa Lim, You-Jung Kang, Jee-Hwan Kim, June-Sung Shim, and Jong-Eun Kim. "Evaluation of the 3D Printing Accuracy of a Dental Model According to Its Internal Structure and Cross-Arch Plate Design: An In Vitro Study." Materials 13, no. 23 (November 28, 2020): 5433. http://dx.doi.org/10.3390/ma13235433.
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The amount of photopolymer material consumed during the three-dimensional (3D) printing of a dental model varies with the volume and internal structure of the modeling data. This study analyzed how the internal structure and the presence of a cross-arch plate influence the accuracy of a 3D printed dental model. The model was designed with a U-shaped arch and the palate removed (Group U) or a cross-arch plate attached to the palate area (Group P), and the internal structure was divided into five types. The trueness and precision were analyzed for accuracy comparisons of the 3D printed models. Two-way ANOVA of the trueness revealed that the accuracy was 135.2 ± 26.3 µm (mean ± SD) in Group U and 85.6 ± 13.1 µm in Group P. Regarding the internal structure, the accuracy was 143.1 ± 46.8 µm in the 1.5 mm-thick shell group, which improved to 111.1 ± 31.9 µm and 106.7 ± 26.3 µm in the roughly filled and fully filled models, respectively. The precision was 70.3 ± 19.1 µm in Group U and 65.0 ± 8.8 µm in Group P. The results of this study suggest that a cross-arch plate is necessary for the accurate production of a model using 3D printing regardless of its internal structure. In Group U, the error during the printing process was higher for the hollowed models.
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Desda, Mia Muchia. "HARGA OPSI SAHAM TIPE AMERIKA DENGAN MODEL BINOMIAL." Jurnal Matematika UNAND 1, no. 1 (October 30, 2012): 44. http://dx.doi.org/10.25077/jmu.1.1.44-50.2012.
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Opsi merupakan hak untuk membeli atau menjual sahamtertentu pada waktu dan harga yang telah ditentukan. Harga saham di-asumsikan memiliki dua nilai periode yang akan datang yaitu naik atauturun begitu pula dengan harga opsi sehingga penentuan harga opsi da-pat didekati dengan model binomial. Pada model harga opsi terdapatbeberapa faktor yang mempengaruhi yaitu harga pelaksanaan K, waktujatuh tempo T, dan harga saham pada saat jatuh tempo T. Parameterdasar yang perlu dicari untuk menentukan harga opsi yaitu tingkat ke-naikan harga saham u, tingkat penurunan harga saham d, harga sahamawal S0, dan probabilitas risiko netral p dan q. Setelah keempat pa-rameter tersebut diperoleh maka harga harga opsi tipe Amerika modelbinomial dapat dimodelkan sebagai berikutvN(SN) = maxfg(SN); 0g= maxfg(SN);11 + r[pVn+1(us) + qVn+1(ds)]gdengan n = N 1;N 2; ; 0 dan p = 1+rd(ud) , q = u1r(ud) , r adalahtingkat suku bunga bebas risiko, serta g(SN) adalah nilai intristik saham,Vn+1(us) adalah nilai intristik opsi saat harga saham naik dan Vn+1(ds)adalah nilai intristik opsi saat harga saham turun.
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Amoretti, G., A. Blaise, R. O. A. Hall, M. J. Mortimer, and R. Troć. "Low-temperature specific heat of U 3 P 4 and Th 3 P 4 . Interpretation of thermodynamic and magnetic properties of U 3 P 4 in a crystal-field model." Journal of Magnetism and Magnetic Materials 53, no. 4 (January 1986): 299–308. http://dx.doi.org/10.1016/0304-8853(86)90173-3.
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Liu, Jinfei, Jian Lou, Junxu Liu, Li Xiong, Jian Pei, and Jimeng Sun. "Dealer." Proceedings of the VLDB Endowment 14, no. 6 (February 2021): 957–69. http://dx.doi.org/10.14778/3447689.3447700.
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Data-driven machine learning has become ubiquitous. A marketplace for machine learning models connects data owners and model buyers, and can dramatically facilitate data-driven machine learning applications. In this paper, we take a formal data marketplace perspective and propose the first en<u> D </u>-to-end mod <u>e</u> l m <u>a</u> rketp <u>l</u> ace with diff <u>e</u> rential p <u>r</u> ivacy ( Dealer ) towards answering the following questions: How to formulate data owners' compensation functions and model buyers' price functions? How can the broker determine prices for a set of models to maximize the revenue with arbitrage-free guarantee, and train a set of models with maximum Shapley coverage given a manufacturing budget to remain competitive ? For the former, we propose compensation function for each data owner based on Shapley value and privacy sensitivity, and price function for each model buyer based on Shapley coverage sensitivity and noise sensitivity. Both privacy sensitivity and noise sensitivity are measured by the level of differential privacy. For the latter, we formulate two optimization problems for model pricing and model training, and propose efficient dynamic programming algorithms. Experiment results on the real chess dataset and synthetic datasets justify the design of Dealer and verify the efficiency and effectiveness of the proposed algorithms.
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Vrana, Radovan, and Jelena Pavičić. "Online sadržaji i usluge namijenjeni djeci na internetskim stranicama dječjih knjižnica u Hrvatskoj." Vjesnik bibliotekara Hrvatske 62, no. 1 (July 30, 2019): 103–27. http://dx.doi.org/10.30754/vbh.62.1.679.
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<p><strong>Cilj</strong>. Cilj istraživanja u ovome radu bio je utvrditi postojanje sadržaja i usluga namijenjenih isključivo djeci na internetskim stranicama dječjih knjižnica u Hrvatskoj te odgovoriti na sljedeća istraživačka pitanja: postoje li i koje su vrste sadržaja (prema predstavljenom japanskom modelu) dostupne putem internetskih stranica dječjih knjižnica u Hrvatskoj i postoje li i koje su usluge za djecu dostupne putem internetskih stranica dječjih knjižnica u Hrvatskoj?</p> <p><strong>Pristup/metodologija/dizajn</strong>. U ovom je istraživanju provedena analiza online sadržaja internetskih stranica dječjih knjižnica u Hrvatskoj u sklopu svih dostupnih internetskih mjesta (bez iznimaka) narodnih knjižnica u Hrvatskoj. Ustanovljen je ukupan broj od 193 dostupna internetska mjesta narodnih knjižnica. Kriterij odabira internetskih stranica dječjih knjižnica u Hrvatskoj u ukupnom broju dostupnih internetskih mjesta narodnih knjižnica bile su one internetske stranice dječjih knjižnica u Hrvatskoj koje su nedvojbeno nudile online sadržaje i usluge namijenjene djeci, njih ukupno 32. Prilikom analize sadržaja internetskih stranica dječjih knjižnica u Hrvatskoj primijenjen je model CIRRI (Core Information Reference Research Instruction (CIRRI) Contents Model) koji su osmislili Kanazawa, Maruyama i Motoki.</p> <p><strong>Rezultati</strong>. Provedeno istraživanje ukazuje na činjenicu kako u odnosu na ukupan broj narodnih knjižnica u Hrvatskoj ne postoji znatan broj narodnih knjižnica koje na svojim internetskim stranicama nude sadržaje i usluge namijenjene djeci. Od svih dostupnih internetskih mjesta narodnih knjižnica u Hrvatskoj koje su pregledane i analizirane, bilo je moguće izdvojiti njih ukupno 32, a među izdvojene 32 rijetke su bile one internetske stranice dječjih knjižnica u Hrvatskoj koje su sadržajima i uslugama namijenjene isključivo djeci. Mnoge od njih teško je locirati u sklopu internetskih mjesta narodnih knjižnica jer nisu bile vidljivo istaknute, nisu bile redovito ažurirane i često su služile samo kao pokazatelji postojanja dječje knjižnice u prostorima narodne knjižnice te postojanja pojedinih stalnih programa pojedinih narodnih knjižnica za djecu koji se odvijaju u prostoru knjižnice. Rijetke su one internetske stranice dječjih knjižnica u Hrvatskoj za koje se može reći da zadovoljavaju potrebe djece za informacijama, znanjem i zabavom. Analizom sadržaja internetskih stranica dječjih knjižnica u Hrvatskoj moguće je zaključiti kako postoji znatan prostor za napredak u ponudi i organizaciji online sadržaja i online usluga za djecu.</p> <p><strong>Praktična primjena</strong>. Rezultate istraživanja moguće je primijeniti u procesu oblikovanja budućih internetskih stranica narodnih knjižnica uz pomoć primjera postojećih vrsta online sadržaja i online usluga.</p>
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Bach, Annika, and Liesel Sommer. "A Γ-convergence result for fluid-filled fracture propagation." ESAIM: Mathematical Modelling and Numerical Analysis 54, no. 3 (April 28, 2020): 1003–23. http://dx.doi.org/10.1051/m2an/2020016.
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In this paper we provide a rigorous asymptotic analysis of a phase-field model used to simulate pressure-driven fracture propagation in poro-elastic media. More precisely, assuming a given pressure p ∈ W 1,∞ (Ω) we show that functionals of the form $$ E(\vec{u})={\int }_{\mathrm{\Omega }} e(\vec{u}):\mathbb{C}e(\vec{u})+p\nabla \cdot \vec{u}+\left\langle \nabla p,\vec{u}\right\rangle\enspace \mathrm{d}x+{\mathcal{H}}^{n-1}({J}_{\vec{u}}),\enspace \vec{u}\in \mathrm{G}{SBD}(\mathrm{\Omega })\cap {L}^1(\mathrm{\Omega };{\mathbb{R}}^n) $$ can be approximated in terms of Γ-convergence by a sequence of phase-field functionals, which are suitable for numerical simulations. The Γ-convergence result is complemented by a numerical example where the phase-field model is implemented using a Discontinuous Galerkin Discretization.
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Morange, P. E., D. Bastelica, M. F. Bonzi, B. Van Hoef, D. Collen, I. Juhan-Vague, and H. R. Lijnen. "Influence of t-PA and u-PA on Adipose Tissue Development in a Murine Model of Diet-Induced Obesity." Thrombosis and Haemostasis 87, no. 02 (2002): 306–10. http://dx.doi.org/10.1055/s-0037-1612990.
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SummaryTo investigate the potential role of tissue-type plasminogen activator (t-PA) or urokinase-type plasminogen activator (u-PA) in development of adipose tissue, we have used a nutritionally induced obesity model in t-PA (t-PA−/−) and u-PA (u-PA−/−) deficient mice. Five week old male wild-type (WT), t-PA−/− or u-PA−/− mice (n = 9 to 16) were fed a high fat diet (HFD, 42% fat). After 16 weeks of HFD, the body weight of t-PA−/− mice was significantly higher than that of WT mice (48 ± 1.1 g vs. 39 ± 2.2 g, p = 0.004). The total weight of the isolated subcutaneous (sc) fat deposit was higher in t-PA−/− than in WT mice (2.4 ± 0.22 g vs. 1.2 ± 0.29 g, p = 0.002), accompanied with higher adipocyte diameters (80 ± 1.7 µm vs. 61 ± 4.7 µm, p < 0.01). These differences were not observed in the intra-abdominal fat deposit. The number of stroma cells in both adipose tissue territories was increased in t-PA−/− as compared to WT mice (2.0 ± 0.13 vs. 1.5 ± 0.10 p = 0.02 and 3.0 ± 0.17 vs 1.6 ± 0.17, p = 0.0001, stroma cells/ adipocytes in sc and intra-abdominal tissue, respectively), partly as a result of an increased number of endothelial cells (192 ± 9 vs. 154 ± 18 p = 0.06 and 108 ± 13 vs. 69 ± 8 p = 0.04 CD31 stained/adipocyte area). In contrast the weight gain and adipose tissue development in u-PA−/− mice was not different from that in WT mice. These data suggest that t-PA but not u-PA plays a role in adipose tissue development.
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Wang, Liming, Xiangxing Ma, Lili Zhang, and Liwei Wang. "Fe3O4 methylprednisolone plus calpain inhibitor protects against spinal cord ischemia-reperfusion injury in rats." Materials Express 10, no. 9 (September 30, 2020): 1554–59. http://dx.doi.org/10.1166/mex.2020.1781.
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To investigate the neuroprotective effects of pretreatment with Fe3O4 methylprednisolone plus calpain inhibitor against spinal cord ischemia-reperfusion injury (SCI) in rats. A total of 18 male Sprague Dawley rats were randomly divided into sham operation, model, and pretreatment + SCI groups (receiving 25 mg/kg Fe3O4 methylprednisolone plus calpain inhibitor) (n = 6 each). The SCI model was established by clamping the left renal inferior abdominal aorta. Hindlimb motor function was evaluated 6, 12, 24, and 48 hours after reperfusion. At 48 hours after reperfusion, spinal cord tissues were collected for histopathological examination, measurement of oxidation product accumulation (malondialdehyde, MDA), and antioxidant enzyme activity assays [superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-PX)]. Motor function scores were compared using non-parametric rank sum (Kruskal-Wallis) test, and mean tissue MDA content and antioxidant enzyme activities were compared using one-way analysis of variance. Compared with the sham operation group, the model group showed significantly increased MDA content (2.95 vs. 5.90 g mg; P = 0.023); significantly increased GSH-Px activity (0.31 vs. 0.78 U/mg; P = 0.001); significantly decreased SOD (16.03 vs. 8.37 U/mg; P = 0.001) and CAT (1.24 vs. 0.54 U/mg; P = 0.002) activities; and significantly decreased hindlimb motor function score at 6 hours (21 to 15.5; P =0.001). Compared with the model group, the pretreatment + SCI group showed significantly decreased MDA content (5.90 vs. 3.27 mg; P = 0.0355); significantly decreased GSH-Px activity (0.78 vs. 0.36 U/mg; P = 0.001); and significantly increased SOD (8.37 vs. 14.79 U/mg; P = 0.001) and CAT (0.54 vs. 0.89 U/mg; P = 0.043) activities. Histopathological changes were significantly less severe in the pretreatment + SCI group than in the model and sham operation groups (P < 0.05). Pretreatment with Fe3O4 methylprednisolone plus calpain inhibitor can prevent SCI by improving the balance between oxidation and antioxidant systems.
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Zhang, Qian, Chaojing Li, Jiayan Luan, Guoping Guan, Jing Lin, Fujun Wang, and Lu Wang. "Polycaprolactone/ultra-high molecular weight polyethylene partially absorbable suture with improved mechanical performances for tendon and ligament repair." Textile Research Journal 90, no. 19-20 (March 24, 2020): 2123–35. http://dx.doi.org/10.1177/0040517520912478.
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Orthopedic suture, as an implantable surgical device for skeletal and soft tissue connection, is vital in tendon or ligament injury repair. Resorbable therapy approaches exhibit excellent biocompatibility in the field of suture materials but lack a long-term fixation effect in orthopedic treatment. Herein, this study focused on a series of partially absorbable orthopedic sutures, which were composed of absorbable polycaprolactone (PCL) multifilament and non-absorbable ultra-high molecular weight polyethylene (UHMWPE) multifilament. Comprehensive in vitro mechanical evaluations were conducted to probe the relationship between material composition and mechanical properties of the sutures. The results showed that the partially absorbable sutures, especially P/U = 50/50 and P/U = 25/75, exhibited significant improvements in mechanical properties compared to single-material sutures. The tensile strength of P/U = 50/50 and P/U = 25/75 was 180.99 and 210.91 N, respectively, which was about two times higher than that of absorbable PCL suture P/U = 100/0 (62.42 N). Furthermore, their suture-to-suture friction force was 1.89 times and 2.51 times that of non-absorbable UHMWPE suture P/U = 0/100, respectively, which guaranteed good knot security. Compared with the clinically used orthopedic suture Ethibond (110 N), P/U = 50/50 and P/U = 25/75 also presented superior tensile properties. Notably, P/U = 50/50 and P/U = 25/75 had similar tensile curves to that of the native tendon/ligament, which might be beneficial to tissue healing. Moreover, the R2 of Eyring's model to simulate the creep curves of each suture was higher than 0.99, which indicated that Eyring's model could be used in predicting the long-term creep behavior of the sutures.
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Gotal, Elvira. "Dokudah – dokumentarni film kao edukacija u predahu u Knjižnici Filozofskog fakulteta u Zagrebu." Vjesnik bibliotekara Hrvatske 61, no. 2 (March 18, 2019): 287–303. http://dx.doi.org/10.30754/vbh.61.2.692.
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<p><strong>Cilj. </strong>Cilj je ovog rada opisati i obrazložiti važnost programa Dokudah koji se provodi u Knjižnici Filozofskog fakulteta u Zagrebu. Program se sastoji od projekcija dokumentarnih filmova i popratne diskusije. Istovremeno, obrazlaže se važnost dokumentarnog filma kao specifičnog oblika audiovizualne građe koji ima sve veću edukacijsku ulogu. Program promiče dokumentarni izričaj, suradnju, kritičko mišljenje i aktivizam, uz to upućuje na važnost audiovizualne građe i njezine zbirke u Knjižnici Filozofskog fakulteta te audiovizualne baštine i kulture općenito.</p> <p><strong>Pristup. </strong>U ovom će se radu obrazložiti teorijska i praktična pozadina programa Dokudah, njegov razvoj i edukativna svrha. Sam termin proizlazi iz akronima sintagme dokumentarni predah i odnosi se na dokumentarni film kao predah u okruženju u kojem prevladavaju knjige te se u tom smislu film javlja kao odmak od čitanja, no istovremeno educira, obrazuje i aktivira pojedince.</p> <p><strong>Rezultati. </strong>Program je nastao 2015. godine i kontinuirano se razvijao s povremenim stankama. Rezultati su provođenog programa uspostavljena suradnja sa studentskim klubovima, nakon toga suradnja s nezavisnim produkcijskim kućama, ispostava i projekcije filmova, aktivno gledanje i poticajna diskusija te, na kraju, osmišljavanje bloga.</p> <p><strong>Ograničenja. </strong>Važna su točka u programu autorska prava. Zbog financijske ograničenosti javne projekcije nisu bile moguće i u tom se smislu čitav Dokudah zasniva na suradnji kao osnovnom načinu izvedbe i provedbe programa. U naknadnim varijantama poput programa Dokudah i zelene knjižnice varijante se mijenjaju i prilagođavaju ovisno o uvjetima autorskog prava.</p> <p><strong>Praktična primjena. </strong>Program Dokudaha ističe važnu ulogu dokumentarnog filma na svim razinama obrazovanja. Zbog rascjepkanosti svojih obaveza na studiju studenti mogu takvim dodatnim programom kvalitetno ispuniti vrijeme između predavanja. Isto tako može se uključiti u koncept otvorene nastave te se provoditi kontinuirano s naznačenim ishodima.</p> <p><strong>Društveni značaj. </strong>Ostvarivanjem kontakata s vanjskim suradnicima omogućuje se aktivnije uključivanje u zajednicu. U tom smislu osmišljen je i blog kako bi na jednom mjestu okupio korisne informacije na temelju kojih bi se pojedinci mogli uključiti u interesnu problematiku.</p> <p><strong>Originalnost. </strong>Knjižnica Filozofskog fakulteta visokoškolska je knjižnica, a po opsegu svojega fonda druga je najveća knjižnica u Hrvatskoj, odmah iza Nacionalne i sveučilišne knjižnice u Zagrebu. Osim knjižne građe, posjeduje i kvalitetnu audiovizualnu zbirku te su važni programi koje provodi radi promicanja te zbirke. Originalnost programa Dokudah proizlazi iz želje i mogućnosti da poveže knjižničare, profesore, studente i vanjske suradnike nudeći raznovrsne sadržaje. Program je prilagodljiv i uklopiv, a da pritom zadržava svoju osnovnu ulogu i zadaću, a to je promicanje dokumentarnog filma. Opisivanjem faza nastanka i koncepta dan je model za oblikovanje srodnih programa.</p>
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YA. BERDNIKOV, A., YA A. BERDNIKOV, M. FABER, A. N. IVANOV, V. A. IVANOVA, A. V. NIKITCHENKO, and N. I. TROITSKAYA. "ON NONLEPTONIC Σ+ → pπ0 DECAY IN THE EFFECTIVE QUARK MODEL WITH CHIRAL U(3) × U(3) SYMMETRY." International Journal of Modern Physics A 22, no. 25 (October 10, 2007): 4651–66. http://dx.doi.org/10.1142/s0217751x07036968.
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Within the effective quark model with chiral U (3) × U (3) symmetry we calculate the S-wave and P-wave amplitudes of the nonleptonic decay Σ+ → pπ0, the partial width and the dynamical polarization of the proton in the dependence on the polarization of the Σ+-hyperon. The theoretical results agree well with the experimental data.
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Handanović, Merima. "IRONIJSKI MODUS HEROJA U DRAMAMA A. P. ČEHOVA / THE IRONIC MODE OF HEROES IN PLAYS BY A. P. CHEKHOV." Journal of the Faculty of Philosophy in Sarajevo / Radovi Filozofskog fakulteta u Sarajevu, ISSN 2303-6990 on-line, no. 23 (November 10, 2020): 305–17. http://dx.doi.org/10.46352/23036990.2020.305.
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The aim of this paper is to investigate the model of the figure of the hero in the plays of Anton Pavlovich Chekhov. In analyzing the model of the figure of the hero, four of the most significant plays by A. P. Chekhov were analyzed in consultation with the literature on the poetics of 20th century drama in order to gain a clearer understanding of how the dramatic world of characters was constructed. Specifically, the focus is on four dramas in four acts: "Three Sisters", "Ivanov", "Seagull" and "Uncle Vanya". For the sake of placing love in the key context of this work, the subject of research is not the drama "Cherry." The paper is entitled thesis on the functioning and construction of characters in dramas based on the principle of irony, and thus sets the goal of examining and proving the title thesis. In doing so, it is very interesting to deal with such a model of hero placed in dramatic situations from the perspective of A. P. Chekhov, a writer who writes his characters as a writer-analyst.
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Τsompos, Constantinos, Constantinos Panoulis, Konstantinos Τοutouzas, George Ζografos, and Apostolos Papalois. "The Effect of the Antioxidant Drug “U-74389G” on Creatinine Levels during Ischemia Reperfusion Injury in Rats." Current Urology 9, no. 2 (2015): 73–78. http://dx.doi.org/10.1159/000442857.
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Objective: The aim of this experimental study was to examine the effect of the antioxidant drug “U-74389G” on a rat model using an ischemia reperfusion protocol. The effect of U-74389G was studied biochemically by measuring mean blood creatinine levels. Materials and Methods: Forty rats were used in the study. Creatinine levels were measured at 60 min of reperfusion (groups A and C) or at 120 min of reperfusion (groups B and D), where groups A and B were controls and groups C and D received U-74389G administration. Results: U-74389G administration significantly decreased the predicted creatinine levels by 21.02 ± 5.06% (p = 0.0001). Reperfusion time non-significantly increased the predicted creatinine levels by 4.20 ± 6.12% (p = 0.4103). However, U-74389G administration and reperfusion time together produced a significant combined effect in decreasing the predicted creatinine levels by 11.69 ± 3.16% (p = 0.0005). Conclusion: Independent of reperfusion time, U-74389G administration significantly decreased the creatinine levels in an ischemic rat model. This study demonstrates that short-term U-74389G administration improves renal function by increasing creatinine excretion.
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Rasouli, S. H. "An ecological model with the p-Laplacian and diffusion." International Journal of Biomathematics 09, no. 01 (November 2, 2015): 1650008. http://dx.doi.org/10.1142/s179352451650008x.
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We study the existence of positive solutions of a population model with diffusion of the form [Formula: see text] where Δp denotes the p-Laplacian operator defined by Δpz = div (∣∇z∣p-2∇z), p > 1, Ω is a bounded domain of RN with smooth boundary, α ∈ (0, 1), a and c are positive constants. Here f : [0, ∞) → R is a continuous function. This model arises in the studies of population biology of one species with u representing the concentration of the species. We discuss the existence of positive solution when f satisfies certain additional conditions. We use the method of sub- and super-solutions to establish our results.
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TOMASSINI, GIUSEPPE, and SERGIO VENTURINI. "MAXIMAL PLURISUBHARMONIC MODELS." International Journal of Mathematics 20, no. 12 (December 2009): 1561–81. http://dx.doi.org/10.1142/s0129167x09005856.
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An analytic pair of dimension n and center V is a pair (V, M) where M is a complex manifold of (complex) dimension n and V ⊂ M is a closed totally real analytic submanifold of dimension n. To an analytic pair (V, M) we associate the class [Formula: see text] of the functions u : M → [0, π/4] which are plurisubharmonic in M and such that u(p) = 0 for each p ∈ V. If [Formula: see text] admits a maximal function u, the triple (V, M, u) is said to be a maximal plurisubharmonic model. After defining a pseudo-metric EV, M on the center V of an analytic pair (V, M) we prove (see Theorem 4.1, Theorem 5.1) that maximal plurisubharmonic models provide a natural generalization of the Monge–Ampère models introduced by Lempert and Szöke in [18].
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TANG, J., and C. S. WARDLE. "Power Output of Two Sizes of Atlantic Salmon (Salmo Salar) at their Maximum Sustained Swimming Speeds." Journal of Experimental Biology 166, no. 1 (May 1, 1992): 33–46. http://dx.doi.org/10.1242/jeb.166.1.33.
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The maximum sustained swimming speeds (Ums) for large (0.45 m long) and small (0.15 m) Atlantic salmon were respectively 0.91ms−1 and 0.54ms−1. Video and cin6 films of fish swimming close to Ums were analysed to obtain variables required for the application of two hydrodynamic models, those of Lighthill and Yates, to determine the mean thrust (T) and mean power output (P) at these swimming speeds (U) close to Ums. A large fish (‘Salmon’) and a small fish (‘Smolt’) were selected for analysis. For salmon using Lighthill's model, T=0.30N and P=0.26W, and using Yates' model, T=0.28N and P=0.25W (U/=0.87ms−1=0.96Ums). For smolt using Lighthill's model, T=0.0052N and P=0.0019W, and using Yates' model, T=0.0065 N and P=0.0024W (U=0.37ms−1=0.69Ums). The power output for smolt swimming at 0.69Ums was corrected to that required to swim at Ums, giving P=0.0059W (Lighthill's model) and P=0.0074W (Yates' model). At Ums it was assumed that all the red muscle was used. Two fish were selected from each size group and cross-sectioned to estimate their red muscle masses. Using a maximum mass-specific power output of 5–8 W kg− for slow red muscle fibres allowed us to calculate that the large and small fish have a power output capacity of 0.125–0.3 W and 0.007–0.019 W, respectively. The power output values at Ums derived from the different approaches for the large (0.25–0.26 W) and small (0.0059–0.0074 W) salmon agree closely. Effects of scaling are discussed.
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Liao, Jianqiao, Yifan Nai, Li Feng, Yimeng Chen, Mei Li, and Huaide Xu. "Walnut Oil Prevents Scopolamine-Induced Memory Dysfunction in a Mouse Model." Molecules 25, no. 7 (April 2, 2020): 1630. http://dx.doi.org/10.3390/molecules25071630.
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For thousands of years, it has been widely believed that walnut is a kind of nut that has benefits for the human body. Walnut oil, accounting for about 70% of walnut, mainly consists of polyunsaturated fatty acids. To investigate the effect of walnut oil on memory impairment in mice, scopolamine (3 mg/kg body weight/d) was used to establish the animal model during Morris Water Maze (MWM) tests. Walnut oil was administrated orally at 10 mL/kg body weight/d for 8 consecutive weeks. The results showed that walnut oil treatment ameliorated the behavior of the memory-impaired mice in the MWM test. Additionally, walnut oil obviously inhibited acetylcholinesterase activity (1.26 ± 0.12 U/mg prot) (p = 0.013) and increased choline acetyltransferase activity (129.75 ± 6.76 U/mg tissue wet weight) in the brains of scopolamine-treated mice (p = 0.024), suggesting that walnut oil could prevent cholinergic function damage in mice brains. Furthermore, walnut oil remarkably prevented the decrease in total superoxide dismutase activity (93.30 ± 5.50 U/mg prot) (p = 0.006) and glutathione content (110.45 ± 17.70 mg/g prot) (p = 0.047) and the increase of malondialdehyde content (13.79 ± 0.96 nmol/mg prot) (p = 0.001) in the brain of scopolamine-treated mice, indicating that walnut oil could inhibit oxidative stress in the brain of mice. Furthermore, walnut oil prevented histological changes of neurons in hippocampal CA1 and CA3 regions induced by scopolamine. These findings indicate that walnut oil could prevent memory impairment in mice, which might be a potential way for the prevention of memory dysfunctions.
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Machala, Dijana. "Hrvatski skupni katalog Nacionalne i sveučilišne knjižnice u Zagrebu te knjižnica iz sustava znanosti i visokog obrazovanja." Vjesnik bibliotekara Hrvatske 61, no. 1 (October 15, 2018): 469–87. http://dx.doi.org/10.30754/vbh.61.1.636.
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<p><strong>Cilj</strong>. Rad ima za cilj prikazati model skupnog kataloga hrvatskih visokoškolskih knjižnica u kontekstu pitanja tehničke, semantičke te organizacijske interoperabilnosti.1</p> <p><strong>Pristup. </strong>U radu se problematizira svojevrsna kriza tradicionalnih knjižničnih kataloga u segmentu tehničkih, ali i normativnih pretpostavki te se izlažu perspektive razvoja skupnih kataloga u kontekstu procesa digitalne transformacije suvremenih knjižnica.</p> <p><strong>Metodologija. </strong>Na prikazu modela skupnog kataloga analiziraju se pitanja interoperabilnosti procesa pronalaženja informacija iz distribuiranih baza knjižničnih kataloga te dijeljenih informacijskih izvora.</p> <p><strong>Rezultati. </strong>Rad zastupa tezu o nužnosti holističkog pristupa, tj. primjeni svojevrsnog okvira za interoperabilnost, ključnog za funkcionalnu uspostavu složenog informacijskog sustava, a koji bi obuhvatio tehničku, semantičku i procesnu, tj. organizacijsku interoperabilnost.</p> <p><strong>Vrijednost. </strong>Rad može biti od vrijednosti svima koji se teorijski ili praktično bave pitanjima pronalaženja informacijskih izvora, ali i knjižničnom suradnjom.</p>
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Rather, Irfan Ahmad, Vivek K. Bajpai, Jonghun Han, and Gyeong-Jun Nam. "Imiquimod-induced psoriasis-like skin inflammation in mouse model." Bangladesh Journal of Pharmacology 11, no. 4 (October 1, 2016): 849. http://dx.doi.org/10.3329/bjp.v11i4.28662.
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<p>Psoriasis is a skin disorder characterized by skin inflammation and plaques. Induction of psoriasis in animal model include following steps: a) Selection of animal model, b) Hair removing from the back or ear, c) treatment of skin with Aldara, a cream containing 5% imiquimod and d) Observation. Imiquimod-induced skin inflammation in animal model resembles with psoriasis.</p><p><strong>Video Clip:</strong></p><p><a href="https://youtube.com/v/QY-RESHbH-U">Psoriaisis-like skin:</a> 9 min 10 sec</p>
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Rayatdoost, Farahnaz, Till Braunschweig, Benjamin Maron, Herbert Schöchl, Necib Akman, Rolf Rossaint, Eva Herzog, Stefan Heitmeier, and Oliver Grottke. "Reversing Rivaroxaban Anticoagulation as Part of a Multimodal Hemostatic Intervention in a Polytrauma Animal Model." Anesthesiology 135, no. 4 (August 9, 2021): 673–85. http://dx.doi.org/10.1097/aln.0000000000003899.
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Background Life-threatening bleeding requires prompt reversal of the anticoagulant effects of factor Xa inhibitors. This study investigated the effectiveness of four-factor prothrombin complex concentrate in treating trauma-related hemorrhage with rivaroxaban-anticoagulation in a pig polytrauma model. This study also tested the hypothesis that the combined use of a low dose of prothrombin complex concentrate plus tranexamic acid and fibrinogen concentrate could improve its subtherapeutic effects. Methods Trauma (blunt liver injury and bilateral femur fractures) was induced in 48 anesthetized male pigs after 30 min of rivaroxaban infusion (1 mg/kg). Animals in the first part of the study received prothrombin complex concentrate (12.5, 25, and 50 U/kg). In the second part, animals were treated with 12.5 U/kg prothrombin complex concentrate plus tranexamic acid or plus tranexamic acid and fibrinogen concentrate. The primary endpoint was total blood loss postinjury. The secondary endpoints (panel of coagulation parameters and thrombin generation) were monitored for 240 min posttrauma or until death. Results The first part of the study showed that blood loss was significantly lower in the 25 U/kg prothrombin complex concentrate (1,541 ± 269 ml) and 50 U/kg prothrombin complex concentrate (1,464 ± 108 ml) compared with control (3,313 ± 634 ml), and 12.5 U/kg prothrombin complex concentrate (2,671 ± 334 ml, all P < 0.0001). In the second part of the study, blood loss was significantly less in the 12.5 U/kg prothrombin complex concentrate plus tranexamic acid and fibrinogen concentrate (1,836 ± 556 ml, P < 0.001) compared with 12.5 U/kg prothrombin complex concentrate plus tranexamic acid (2,910 ± 856 ml), and there were no early deaths in the 25 U/kg prothrombin complex concentrate, 50 U/kg prothrombin complex concentrate, and 12.5 U/kg prothrombin complex concentrate plus tranexamic acid and fibrinogen concentrate groups. Histopathologic analyses postmortem showed no adverse events. Conclusions Prothrombin complex concentrate effectively reduced blood loss, restored hemostasis, and balanced thrombin generation. A multimodal hemostatic approach using tranexamic acid plus fibrinogen concentrate enhanced the effect of low doses of prothrombin complex concentrate, potentially reducing the prothrombin complex concentrate doses required for effective bleeding control. Editor’s Perspective What We Already Know about This Topic What This Article Tells Us That Is New
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Petitta, Francesco. "A non-existence result for nonlinear parabolic equations with singular measures as data." Proceedings of the Royal Society of Edinburgh: Section A Mathematics 139, no. 2 (March 25, 2009): 381–92. http://dx.doi.org/10.1017/s0308210507001163.
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In this paper we prove a non-existence result for nonlinear parabolic problems with zero lower-order terms whose model iswhere Δp=div(|∇u|p−2∇u) is the usual p-laplace operator, λ is measure concentrated on a set of zero parabolic r-capacity (1<p<r) and q is large enough.
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Wilson, J. R., R. Falcone, N. Ferraro, and J. Egler. "Mechanism of skeletal muscle underperfusion in a dog model of low-output heart failure." American Journal of Physiology-Heart and Circulatory Physiology 251, no. 2 (August 1, 1986): H227—H235. http://dx.doi.org/10.1152/ajpheart.1986.251.2.h227.
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To investigate the mechanism responsible for underperfusion of working skeletal muscle in heart failure, we measured systemic and femoral bed hemodynamics during treadmill exercise and gracilis muscle resistance during contraction frequencies of 1-9 Hz in 8 dogs ventricularly paced at 260 beats/min for 3 wk to induce heart failure (HF) and in 9 control dogs. At peak treadmill exercise (4 mph, 10%), HF dogs had reduced cardiac outputs (control: 297 +/- 42 vs. HF: 212 +/- 16 ml X min-1 X kg-1) and femoral bed flows (control: 352 +/- 112 vs. HF: 229 +/- 95 ml/min) and elevated arterial lactates [control: 1.7 +/- 0.7 vs. HF: 4.1 +/- 0.7 mM (all P less than 0.04)], consistent with skeletal muscle underperfusion. This muscle underperfusion was associated with reduced mean arteriovenous pressure gradients [control: 119 +/- 12 vs. HF: 91 +/- 9 mmHg (P less than 0.001)] but with normal systemic vascular [control: 21 +/- 6 vs. HF: 23 +/- 5 U (P = NS)] and femoral bed resistances [control: 3.5 +/- 1.6 vs. HF: 4.4 +/- 2.3 X 10(2) U (P = NS)]. Both groups also had similar gracilis muscle minimal resistance during exercise (control: 2.0 +/- 1.1 vs. HF: 1.9 +/- 0.9 X 10(3) U/100 g) and following maximal vasodilation (control: 2.0 +/- 1.0 vs. HF: 2.1 +/- 1.0 X 10(3) U/100 g). These results suggest that 1) short-term rapid ventricular pacing in the dog produces a model of low output HF resembling HF in humans, and 2) skeletal muscle underperfusion in this model is due to a reduced muscle arteriovenous pressure gradient and not to impaired skeletal muscle arteriolar vasodilation.
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Larmann, Jan, Tim Frenzel, Anke Hahnenkamp, Christine Herzog, Anika Lorenz, Andrea U. Steinbicker, Simone Calmer, et al. "In Vivo Fluorescence-mediated Tomography for Quantification of Urokinase Receptor-dependent Leukocyte Trafficking in Inflammation." Anesthesiology 113, no. 3 (September 1, 2010): 610–18. http://dx.doi.org/10.1097/aln.0b013e3181e99bfc.
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Background Inflammation is characterized by leukocyte recruitment. Macrophages and neutrophils contribute to tissue damage and organ dysfunction. Modulating leukocyte invasion can protect from these adverse effects. Leukocyte recruitment critically depends on the urokinase-type plasminogen activator receptor (u-PAR). We here use a novel technique to longitudinally quantify cell trafficking in inflammatory models in live animals. Methods Near-infrared fluorophore-labeled leukocytes were adoptively transferred to mice with thioglycollate peritonitis to study leukocyte trafficking to sites of inflammation. Macrophage and neutrophil trafficking was followed with three-dimensional fluorescence-mediated-tomography. u-PAR-/- and wild-type macrophage recruitment was studied by cross-over adoptive cell transfer to elucidate the role of leukocytic versus u-PAR expressed on other cells. Endotoxic shock-induced pulmonary inflammation was used to study u-PARs role for pulmonary neutrophil recruitment. Results Mice experiencing peritonitis showed a significant increase in mean fluorescence intensity because of enhanced macrophage (315%, n=9-10), P<0.05) or neutrophil (194%, n=6, P<0.02) recruitment. Fluorescence-mediated-tomography uncovered a macrophage recruitment defect in the peritonitis model for u-PAR-/- mice (147% of baseline) compared with control mice (335% of baseline, n=8-9, P<0.05). When u-PAR-/--macrophages were transferred to wild-type mice fluorescence intensity increased to 145% while wild-type macrophage transfer into u-PAR-/- resulted in 192% increase compared with baseline (n=6, P<0.05). Reduced neutrophil recruitment in pulmonary inflammation in u-PAR-/- mice was accompanied by improved pulmonary gas exchange. Conclusion Using noninvasive in vivo fluorescence-mediated tomography to image leukocyte recruitment in inflammatory mouse models, we describe a novel macrophage recruitment defect in u-PAR-/- mice. Targeting u-PAR for modulation of leukocyte recruitment is a promising therapeutic strategy to ameliorate leukocyte induced tissue damage.
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Darondeau, Philippe, and Boubakar Gamatie. "Infinitary Behaviours and Infinitary Observations." Fundamenta Informaticae 13, no. 3 (July 1, 1990): 353–86. http://dx.doi.org/10.3233/fi-1990-13308.
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We present a denotational model for CCS, accounting for finite as well as infinite behaviours. The meanings of programs are combinations of ready sets and infinitary languages. The model is shown fully abstract w.r.t. the equivalence u ∼ v if L(u,t)=L(v,t) for any testing program t, where L(p,q) is the set of totally ordered traces of communications between programs p and q set in parallel.
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Vitori, Vera, Petra Stulić, and Matea Bakmaz. "Program informacijsko opismenjavanje tinejdžera Gradske knjižnice Zadar." Vjesnik bibliotekara Hrvatske 61, no. 1 (October 15, 2018): 127–50. http://dx.doi.org/10.30754/vbh.61.1.655.
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<p><strong>Cilj. </strong>Rad ukazuje na važnost provođenja programa informacijskog opismenjavanja u narodnim knjižnicama. Cilj je rada prikazati program Informacijsko opismenjavanje tinejdžera Gradske knjižnice Zadar i rezultate istraživanja koje je provedeno radi vrednovanja programa. U istraživanju se analizira zadovoljstvo i mišljenje sudionika programa, učenika osnovnih i srednjih škola, s obzirom na njegovu jasnoću, razumljivost, korisnost i zanimljivost.</p> <p><strong>Metodologija. </strong>U anketnom istraživanju programa Informacijsko opismenjavanje ti-</p> <p>nejdžera za prikupljanje podataka korišten je anketni upitnik kreiran za tu svrhu.</p> <p><strong>Rezultati. </strong>Rezultati istraživanja pokazali su da je u narodnoj knjižnici moguće osmisliti i provesti kvalitetne programe poput programa Informacijsko opismenjavanje tinejdžera u Gradskoj knjižnici Zadar. Rezultati pokazuju da učenici osnovnih i srednjih škola u velikom postotku pozitivno ocjenjuju zanimljivost teme, jasnu i razumljivu prezentaciju sadržaja i stjecanje novih znanja za koja smatraju da će im koristiti u daljnjem školovanju.</p> <p><strong>Originalnost. </strong>Rad nastoji ukazati na potrebu provođenja programa informacijskog opismenjavanja, kakav je za tinejdžersku populaciju u narodnoj knjižnici rijetkost. Opisujući faze nastanka, koncept i promidžbene aktivnosti programa Informacijsko opismenjavanje tinejdžera Gradske knjižnice Zadar, dan je model za oblikovanje srodnih programa. U hrvatskoj stručnoj literaturi nedovoljno je istraživanja na temu informacijske pismenosti u narodnim knjižnicama, a vrednovanja programa opismenjavanja tinejdžera gotovo da i nema. Rezultati vrednovanja programa s obzirom na učenike osnovnih i srednjih škola mogu poslužiti kao polazište u formiranju sadržaja sličnih programa te kao smjerokaz za unapređivanje postojećih.</p>
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Charles, Anthony, Almaasa Shaikh, Madonna Walters, Susan Huehl, and Richard Pomerantz. "Blood Transfusion is an Independent Predictor of Mortality after Blunt Trauma." American Surgeon 73, no. 1 (January 2007): 1–5. http://dx.doi.org/10.1177/000313480707300101.
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Allogeneic blood transfusion is associated with increased morbidity and mortality. The authors evaluated the affect of blood transfusion, independent of injury severity on mortality. The authors conducted a retrospective review of all patients, age ≥18 years with blunt injury admitted to their Level 2 trauma center from 1994 to 2004 by query of the NTRACS trauma registry. Initial systolic blood pressure and heart rate determined the shock index. Logistic regression was used to model the affect of blood transfusion on mortality. Transfusion requirements were categorized as follows: A, 0 U; B, 1 to 2 U; C, 3 to 5 U; D, ≥6 U blood. In this sample of 8215 blunt trauma patients, 324 patients received blood transfusion. Mortality rates between the transfused and nontransfused groups were 15.12 per cent and 1.84 per cent ( P < 0.000) respectively. In the logistic regression model, transfusion category B did not have a significant affect on the odds of death ( P = 0.176); the affect of transfusing 3 to 5 U and ≥6 U had a mortality odds ratio of 3.22 ( P = 0.002) and 4.87 ( P = 0.000) respectively. Transfusing ≥2U blood was strongly associated with mortality in this blunt trauma population. There must be a continuous attempt to limit blood transfusion when feasible and physiologically appropriate.
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L. Bhuiyan, Abdul. "Application of the Concept of Nuclear ud Pair Clusters." Applied Physics Research 8, no. 2 (February 20, 2016): 29. http://dx.doi.org/10.5539/apr.v8n2p29.
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<p class="1Body">In a previous paper, the author of this paper presented a model in which it was proposed that the nuclei consist of clusters of ud pairs, where u and d are u quark and d quark, respectively. In this paper, the author has used the model in elucidating several phenomena, such as binding of u and d in ud by the exchange of electron-positron pairs or photons between them, energy of the exchanged photons, nature of forces between u and d, interaction of energetic photons with nuclear ud pairs, existence of nuclear quadrupole moment, creation of dark matter via simultaneous increase of h and decrease of c as the universe expands, etc.</p>
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Layton, H. E., John M. Davies, Giovanni Casotti, and Eldon J. Braun. "Mathematical model of an avian urine concentrating mechanism." American Journal of Physiology-Renal Physiology 279, no. 6 (December 1, 2000): F1139—F1160. http://dx.doi.org/10.1152/ajprenal.2000.279.6.f1139.
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A mathematical model was used to investigate how concentrated urine is produced within the medullary cones of the quail kidney. Model simulations were consistent with a concentrating mechanism based on single-solute countercurrent multiplication and on NaCl cycling from ascending to descending limbs of loops of Henle. The model predicted a urine-to-plasma (U/P) osmolality ratio of ∼2.26, a value consistent with maximum avian U/P osmolality ratios. Active NaCl transport from descending limb prebend thick segments contributed 70% of concentrating capability. NaCl entry and water extraction provided 80 and 20%, respectively, of the concentrating effect in descending limb flow. Parameter studies indicated that urine osmolality is sensitive to the rate of fluid entry into descending limbs and collecting ducts at the cone base. Parameter studies also indicated that the energetic cost of concentrating urine is sensitive to loop of Henle population as a function of medullary depth: as the fraction of loops reaching the cone tip increased above anatomic values, urine osmolality increased only marginally, and, ultimately, urine osmolality decreased.
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Pasha, SK Abdul, and N. Prema Kumar. "Model Predictive Controller based Unified Power Quality Conditioner for Voltage Regulation Studies in 33- Bus Closed Loop Distribution System." E3S Web of Conferences 184 (2020): 01073. http://dx.doi.org/10.1051/e3sconf/202018401073.
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Recent developments in FACTS have produced U.P.Q.C to mitigate sag and attenuate THD. U.P.Q.C has been urbanized as a FACTS controller between feeding end & far end of distribution system .The U-P-Q-C is capable of improving the voltage profile & reducing THD of distribution system by regulating the voltage using PR (Proportional-Resonant-Controller) and MPC (Model-Predictive) controller. This work proposes U-P-Q-C for Thirty Three Bus Systems .The objective of this work is to enhance-voltage-profile of T-T-B-S. The T-T-B-S in open loop & closed loop-TTBS- U-P-Q-C using PR and MPC-controllers are-modeled,pretend & their consequences are represented. Responses are estimated as a time of settle and error in steady state. The outcomes indicate that MP Controlled T-T-B-S system has better response than PR controlled T-T-B-S system.
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Ravesloot, Christoph Maria. "Determining Thermal Specifications for Vegetated GREEN Roofs in Moderate Winter Climates." Modern Applied Science 9, no. 13 (November 30, 2015): 208. http://dx.doi.org/10.5539/mas.v9n13p208.
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<p class="zhengwen">Because local weather conditions in moderate climates are changing constantly, heat transfer specifications of substrate and vegetation in vegetated green roofs also change accordingly. Nevertheless, it is assumed that vegetated green roofs can have a positive effect on the thermal performance of construction in winter conditions. Is there proof from scientific research and field testing for this assumption? To answer this question, research is conducted with the main research question: Which parameters defining thermal performance for vegetated green-roof construction for a moderate winter climate like that in the Netherlands can be determined from existing literature, and how do these parameters influence thermal performance? Literature research was executed on monitoring and testing of thermal specifications of vegetated green roofs. Models with physical parameters on vegetated green roofs were studied and compared. The first goal was to make a list of all physical parameters and corresponding variables valid in the Dutch moderate-winter climate. None of the models that were found in the literature seemed to cover all physical processes. These models use parameters and variables to calculate the overall u-value of substrate and vegetation. Nevertheless, one nearly complete model was used for a sensitivity test on variables. Maximum and minimum values of variables were calculated in the model to determine the influence on the outcome in terms of u-value. From this analysis, a distinction could be made between variables influencing the u-value strongly and other variables influencing the outcome weakly.</p><p class="zhengwen">The modelling showed that three variables were influencing the model calculations moderately strongly and therefore the thermal performance of the vegetated green-roof substrate and vegetation. These variables are not consistent with parameters modeling or calculating u-value in constructions. This finding means that contribution to thermal insulation by extensive vegetated green-roof substrate and vegetation in terms of u-value would be negligible. Only a small theoretical contribution to thermal insulation can be argued from weak variables. To be sure about this small theoretical contribution to the u-value of the roof construction, this u-value was used as input for energy-use calculations for residential buildings. These calculations show that such a small increase of the u-value leads to no visible reduction in energy use for heating in winter conditions. The contribution is negligible compared to the influence of the u-value from extra insulation under the roof.</p>For vegetated green roofs in such moderate winter climates as in the Netherlands, additional u-value will have to be proven specifically, because the modelling shows that, in general, no contribution to thermal insulation can be expected.
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Fan, Si, Samnhita Raychaudhuri, Olivia Kraus, Md Shahinozzaman, Leila Lofti, and Diana N. Obanda. "Urtica dioica Whole Vegetable as a Functional Food Targeting Fat Accumulation and Insulin Resistance-a Preliminary Study in a Mouse Pre-Diabetic Model." Nutrients 12, no. 4 (April 10, 2020): 1059. http://dx.doi.org/10.3390/nu12041059.
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The shoot of Urtica dioica is used in several cultures as a vegetable or herb. However, not much has been studied about the potential of this plant when consumed as a whole food/vegetable rather than an extract for dietary supplements. In a 12-week dietary intervention study, we tested the effect of U. dioica vegetable on high fat diet induced obesity and insulin resistance in C57BL/6J mice. Mice were fed ad libitum with isocaloric diets containing 10% fat or 45% fat with or without U. dioica. The diet supplemented with U. dioica attenuated high fat diet induced weight gain (p < 0.005; n = 9), fat accumulation in adipose tissue (p < 0.005; n = 9), and whole-body insulin resistance (HOMA-IR index) (p < 0.001; n = 9). Analysis of gene expression in skeletal muscle showed no effect on the constituents of the insulin signaling pathway (AKT, IRS proteins, PI3K, GLUT4, and insulin receptor). Notable genes that impact lipid or glucose metabolism and whose expression was changed by U. dioica include fasting induced adipocyte factor (FIAF) in adipose and skeletal muscle, peroxisome proliferator-activated receptor-α (Ppar-α) and forkhead box protein (FOXO1) in muscle and liver, and Carnitine palmitoyltransferase I (Cpt1) in liver (p < 0.01). We conclude that U. dioica vegetable protects against diet induced obesity through mechanisms involving lipid accumulation and glucose metabolism in skeletal muscle, liver, and adipose tissue.
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Novitasari, Maya, and Heidy Paramitha Devi. "ANALISIS PERBANDINGAN PORTOFOLIO OPTIMAL PADA SAHAM SRI KEHATI DENGAN MENGGUNAKAN MODEL INDEKS TUNGGAL DAN MODEL RANDOM." INVENTORY: JURNAL AKUNTANSI 1, no. 2 (April 12, 2018): 188. http://dx.doi.org/10.25273/inventory.v1i2.2439.
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<p><em>The purpose of this study is to provide empirical evidence that the determination of a stock portfolio using a single index model can provide optimal returns compared with the determination of stock portfolio using a random model. The sample in this research is 25 shares joined in SRI-KEHATI selected using purposive sampling. The data analysis technique used the average test for two independent samples (Mann Whitney Test (U Test)). The results showed that the determination of the stock portfolio using a single index model can provide optimal return compared to the determination of stock portfolio using random model.</em></p>
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YA. BERDNIKOV, A., YA A. BERDNIKOV, M. FABER, A. N. IVANOV, V. A. IVANOVA, A. V. NIKITCHENKO, and N. I. TROITSKAYA. "ON NONLEPTONIC DECAYS OF THE Λ0-HYPERON IN THE EFFECTIVE QUARK MODEL WITH CHIRAL U(3)×U(3) SYMMETRY." International Journal of Modern Physics A 22, no. 10 (April 20, 2007): 1835–47. http://dx.doi.org/10.1142/s0217751x07036373.
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Within the effective quark model with chiral U (3) × U (3) symmetry we calculate the S-wave and P-wave amplitudes and the partial widths of the nonleptonic decays of the Λ0-hyperon, Λ0 → pπ- and Λ0 → nπ0. The theoretical results agree well with the experimental data. The angular distributions of the decay rates in dependence on the polarizations of baryons are analyzed both in the laboratory frame and in the rest frame of the Λ0-hyperon.
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Bidaut-Véron, Marie-Françoise, and Quoc-Hung Nguyen. "Evolution equations of p-Laplace type with absorption or source terms and measure data." Communications in Contemporary Mathematics 17, no. 06 (October 29, 2015): 1550006. http://dx.doi.org/10.1142/s0219199715500066.
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Let Ω be a bounded domain of ℝN, and Q = Ω × (0, T). We consider problems of the type [Formula: see text] where Δpis the p-Laplacian, μ is a bounded Radon measure, u0∈ L1(Ω), and ±𝒢(u) is an absorption or a source term. In the model case 𝒢(u) = ±|u|q-1u (q > p-1), or 𝒢, has an exponential type. We prove the existence of renormalized solutions for any measure μ in the subcritical case, and give sufficient conditions for existence in the general case, when μ is good in time and satisfies suitable capacitary conditions.
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Tatsien, Li, Tan Yongji, and Peng Yuejun. "Mathematical model and method for spontaneous potential well-logging." European Journal of Applied Mathematics 5, no. 2 (June 1994): 123–39. http://dx.doi.org/10.1017/s0956792500001352.
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Spontaneous potential well-logging is an important technique in petroleum exploitation. To make the corresponding log interpretation chart, it is supposed that the geometrical structure of the formation, the resistivity in each subdomain, and the spontaneous potential difference on each interface are all known; then in the direct problem, the spontaneous potential u = u(r, z) satisfies an elliptic boundary value problem with jump conditions on interfaces. At the joint points A and B of the interfaces (figure 2), the jumps of the spontaneous potential do not, in general, satisfy the compatibility condition. It turns out that it is impossible to find a piecewise H1 solution to the problem, and the standard finite element method cannot be applied to get an approximate solution. In this paper, by means of a method of removing the singularities at A and B, it is proved that the problem admits a unique weak solution that is piecewise W1,p for any fixed p with 1 ≤ p <2. Moreover, based on this method a numerical scheme is suggested, and some numerical examples and some conclusions of practical interest are given. The techniques used in this paper will find a wider applicability in other problems.
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Lebacle, Cedric Michel, Aydin Pooli, Nagesh Rao, Erika Louise Wood, Nils Kroeger, Hyun J. Kim, Izak Faiena, et al. "The UCLA Histo-Genetic Risk Classification (U-HGRC) to predict outcomes of localized clear cell renal cell carcinoma." Journal of Clinical Oncology 37, no. 7_suppl (March 1, 2019): 627. http://dx.doi.org/10.1200/jco.2019.37.7_suppl.627.
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627 Background: Thirty percent of patients with localized clear cell renal cell carcinoma (ccRCC) will ultimately develop recurrence (local or metastatic) after nephrectomy. Current risk stratification systems still misclassify patients. We have developed a novel classification integrating cytogenetic findings to better stratify the risk of recurrence and overall survival (OS) after surgery for localized ccRCC. Methods: A total of 646 patients from UCLA with ccRCC and tumor cytogenetic analysis, were included in this study. After a selection of histologic parameters using logistic regression and cytogenetic parameters using principal component analysis a CHAID decision tree and Kaplan Meier analysis were used to build the UCLA Histo-Genetic Risk Classification (U-HGRC). Survival analyses of the model were validated on two random samples of 323 patients. Recurrence was defined as any local recurrence or development of new metastasis after surgery. Results: The T-stage, tumor size, presence of sarcomatoid features, gain of chromosome 5q, loss 10q, or loss X/Y were used to stratify the risk of recurrence of ccRCC into three U-HGRC groups of low (1), intermediate (2) or high-risk (3). After a mean follow-up of 55 months, risk of recurrence (HR = 2.44, p = .001 for U-HGRC 2; HR = 9.90, p < .0001 for U-HGRC 3), disease-free survival (DFS) (Log-rank p < .0001), risk of death (HR = 1.72, p = .033 for U-HGRC 2; HR = 4.74, p < .0001 for U-HGRC 3) and OS (Log-rank p < .0001) were significantly different between groups. These findings were validated on two random samples. For high-risk group, median DFS and OS were 2.7 and 6.3 years, respectively. The 5-year risks of recurrence for U-HGRC group 1, 2 and 3 were 9%, 25% and 62%, respectively. The AUC of the model was significantly improved comparing to the current UISS system (0.72 for U-HGRC vs 0.65 for UISS, p = .008) with an accuracy of 82.8% for the U-HGRC high-risk group. Conclusions: The U-HGRC, which integrates genomic alterations with clinical and pathologic features, allowed a better stratification of recurrence risk and overall survival that could help to select appropriate patients for surveillance and adjuvant therapy protocols.
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King, Wesley A., Keith L. Black, Kiyonobu Ikezaki, Scott Conklin, and Donald P. Becker. "Tumor-associated neurological dysfunction prevented by lazaroids in rats." Journal of Neurosurgery 74, no. 1 (January 1991): 112–15. http://dx.doi.org/10.3171/jns.1991.74.1.0112.
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✓ The efficacy of U-74006F and U-78517F in the treatment of blood-tumor barrier permeability and tumor-associated neurological dysfunction was evaluated in a brain-tumor model in rats. U-74006F is a 21-aminosteroid and U-78517F is a 2-methylamino chroman. Rats with stereotactically implanted Walker 256 tumors were treated with methylprednisolone, U-74006F, U-78517F, or vehicle (0.05 N HCl) on Days 6 through 10 following implantation. Neurological function and vascular permeability were assessed on Day 10. Methylprednisolone and U-74006F were equally effective at preventing neurological dysfunction compared to the control group (p < 0.01); U-78517F was slightly less effective than U-74006F and methylprednisolone but was significantly better than vehicle in preventing neurological dysfunction. Delivery of methylprednisolone resulted in a significant decrease in tumor vascular permeability (p < 0.006) while U-74006F and U-78517F had no effect on permeability. This suggests that U-74006F and U-78517F prevented tumor-associated neurological dysfunction by a mechanism other than decreasing permeability in tumor capillaries, and that U-74006F or U-78517F could prove useful in the treatment of brain tumors.
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Kocharov, Sergey L., Henry A. Panosyan, Paweł Marzęda, Paula Wróblewska-Łuczka, Ewelina Kochman, Aleksandra Wlaź, and Jarogniew J. Łuszczki. "ANTICONVULSANT POTENCY OF 10 VARIOUS P-ISOPROPOXYPHENYLSUCCINIMIDE DERIVATIVES IN THE MAXIMAL ELECTROSHOCK-INDUCED SEIZURE THRESHOLD MODEL IN MICE." Health Problems of Civilization 3 (2017): 195–201. http://dx.doi.org/10.5114/hpc.2017.70010.
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Kumar, S., and S. Roy. "A parametric study of a blown powder laser cladding and alloying process using a two-dimensional conduction model." Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science 218, no. 7 (July 1, 2004): 703–9. http://dx.doi.org/10.1243/0954406041319473.
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A two-dimensional model has been developed to predict the temperature field and melt pool shape during blown powder laser cladding. A finite volume method has been used to solve the two-dimensional energy equation for a body moving relative to a stationary laser heat source. A boundary fitted coordinate system has been employed as the built-up surface geometry is complex. Important dimensionless groups representing laser parameters power ( P) and scanning speed ( U) and the process parameters built-up height and average dilution are identified. The effect of laser parameters on process parameters is investigated. For cladding P/U should always be kept low (less than 1) to reduce the average dilution, and in order to achieve the desired clad height the power level P should be controlled.
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Melani, Ade Emelan T., I. Made Candiasa, and I. Gst Nyoman Yudi Hartawan. "PENGARUH PENERAPAN MODEL PEMBELAJARAN PAIR CHECK TERHADAP KEMAMPUAN NUMERIK SISWA KELAS VII SMP NEGERI 3GIANYAR." Jurnal Pendidikan Matematika Undiksha 10, no. 1 (September 3, 2019): 1. http://dx.doi.org/10.23887/jjpm.v10i1.19900.
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Penelitian ini bertujuan untuk mengkaji pengaruh model pembelajaran Pair Check terhadap kemampuan numerik siswa. Jenis penelitian ini adalah eksperimen semu dengan post-test only control group design. Populasi penelitian ini adalah siswa kelas VII SMP Negeri 3Gianyar tahun ajaran 2017/2018 yang berjumlah 383 orang siswa dan tersebar dalam 10 kelas. Sampel ditentukan dengan teknik cluster random sampling setelah dilakukan uji kesetaraan kelas menggunakan uji ANAVA. Kelas VII B yang terpilih sebagai kelompok eksperimen dan kelas VII A sebagai kelompok kontrol. Data kemampuan numerik siswa diperoleh melalui tes obyektif. Data dianalisis menggunakan uji U Mann-Whitney. Berdasarkan hasil pengujian dengan uji U Mann-Whitney, diperoleh rata-rata peringkat untuk siswa kelompok eksperimen adalah 43,62dan rata-rata peringkat kelompok kontrol adalah 33,38. Nilai U sebesar 527,500 dengan p value = 0,0188 dan α = 0,05 jadi p value<α yang berarti H0 ditolak dan menunjukkan bahwa kemampuan numerik siswa kelas VII SMP Negeri 3 Gianyar yang dibelajarkan dengan model pembelajaran pair check lebih tinggi daripada siswa yang dibelajarkan dengan pembelajaran konvensional. Dengan demikian dapat disimpulkan bahwa model pembelajaran pair check berpengaruh positif terhadap kemampuan numerik siswaKata Kunci: Model pembelajaran pair check, kemampuan numerik