Academic literature on the topic 'Tumour suppressor'
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Journal articles on the topic "Tumour suppressor"
Wagner, K. J., and S. G. E. Roberts. "Transcriptional regulation by the Wilms' tumour suppressor protein WT1." Biochemical Society Transactions 32, no. 6 (October 26, 2004): 932–35. http://dx.doi.org/10.1042/bst0320932.
Full textSwale, V. J., and A. G. Quinn. "Tumour suppressor genes." Clinical and Experimental Dermatology 25, no. 3 (May 2000): 231–35. http://dx.doi.org/10.1046/j.1365-2230.2000.00620.x.
Full textCowell, J. K. "Tumour suppressor genes." Annals of Oncology 3, no. 9 (November 1992): 693–98. http://dx.doi.org/10.1093/oxfordjournals.annonc.a058319.
Full textKLEIN, G. "Tumour suppressor genes." Journal of Cell Science 1988, Supplement 10 (February 1, 1988): 171–80. http://dx.doi.org/10.1242/jcs.1988.supplement_10.13.
Full textVile, R. "Tumour suppressor genes." BMJ 298, no. 6684 (May 20, 1989): 1335–36. http://dx.doi.org/10.1136/bmj.298.6684.1335.
Full textMaehama, T., F. Okahara, and Y. Kanaho. "The tumour suppressor PTEN: involvement of a tumour suppressor candidate protein in PTEN turnover." Biochemical Society Transactions 32, no. 2 (April 1, 2004): 343–47. http://dx.doi.org/10.1042/bst0320343.
Full textClurman, Bruce, and Mark Groudine. "Defining tumour-suppressor genes." Nature 389, no. 6647 (September 1997): 123. http://dx.doi.org/10.1038/38119.
Full textMcCarthy, Nicola. "Surviving the tumour suppressor." Nature Reviews Molecular Cell Biology 8, no. 7 (July 2007): 516. http://dx.doi.org/10.1038/nrm2214.
Full textBangham, Jenny. "Tumour-suppressor super models." Nature Reviews Cancer 5, no. 2 (January 20, 2005): 84. http://dx.doi.org/10.1038/nrc1554.
Full textBangham, Jenny. "Tumour suppressor super models." Nature Reviews Genetics 6, no. 2 (February 2005): 91. http://dx.doi.org/10.1038/nrg1546.
Full textDissertations / Theses on the topic "Tumour suppressor"
de, Foy K. "Analysis of candidate tumour suppressor genes in sporadic ovarian tumours." Thesis, University of Cambridge, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.598448.
Full textLiu, Lu. "Oncogenes and tumour suppressor genes in human central nervous system tumours /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3532-7/.
Full textDiscenza, Maria Teresa. "Regulation of expression of the Wilms' tumour 1 tumour suppressor gene." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=82855.
Full textWe have identified a novel trans-acting factor, named complex D, which shows sequence specific binding to the WT1 promoter. By electrophoretic mobility shift assays (EMSA), we demonstrate that the transcription factor Sp1 binds the WT1 promoter at a site overlapping the complex D binding site. Molecular mass determination experiments and in situ UV crosslinking indicate that complex D is approximately 130 kDa and consists of at least two proteins. Transient transfection assays show that the integrity of the complex D binding site is necessary for maximal activation of a reporter gene, suggesting that complex D may function as an activator.
Similar to WT1, the ETS-domain transcription factor Pea3 is expressed in tissues where mesenchymal-epithelial interactions occur and both gene products are implicated in regulating the expression of genes necessary for the epithelialization of common organs. Transient transfection assays using WT1 promoter-reporter gene constructs identified a Pea3 responsive element in the WT1 promoter. Overexpression of Pea3 transactivates the WT1 promoter and the presence of the intact Pea3 responsive element is necessary for the transactivation. We demonstrate, by EMSA, the sequence specific binding of Pea3 to the responsive element.
WT1 and the paired box domain transcription factor Paired box 2 (Pax2) are expressed at the initial stages of metanephric kidney development and are critical for the initiation of nephrogenesis. We generated WT1/Pax2 compound heterozygous mutant mice to provide an in vivo model for studying the interplay between WT1 and Pax2 during nephrogenesis. WT1+/-/Pax2 1Neu/+ kidneys were 50% smaller that wild type kidneys and displayed a more severe underdevelopment of the medulla, renal calyces and renal pelvis compared to Pax21Neu/+ kidneys. We demonstrate that WT1 and Pax2 proteins physically interact in vitro and in vivo. Our data suggest that WT1 is a modifier of the Pax2 mutant phenotype and that both proteins may be implicated in a common pathway in the transcriptional network governing metanephric development.
Judson, Hannah. "Investigation of candidate imprinted tumour suppressor genes." Thesis, University of Edinburgh, 2001. http://hdl.handle.net/1842/28316.
Full textMancini, DiNardo Debora. "Methylation-mediated inactivation of tumour suppressor genes." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0021/NQ58149.pdf.
Full textPatel, Anjla Chhotubhai. "The role of fat tumour suppressor gene." Thesis, University of Cambridge, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.619808.
Full textMarcar, Lynnette Nongkynrih. "Inhibition of p53 tumour suppressor function by tumour associated MAGE-A proteins." Thesis, University of Dundee, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.521696.
Full textBurns, Alice Sin Ying Wai. "The role of the p53 tumour suppressor pathway in central primitive neuroectodermal tumours." Thesis, University of Newcastle Upon Tyne, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300357.
Full textWang, Yemin. "Role of tumour suppressor ING3 in melanoma pathogenesis." Thesis, University of British Columbia, 2009. http://hdl.handle.net/2429/3850.
Full textMarston, Nicola Jane. "Mutational analysis of the tumour suppressor protein, p53." Thesis, Imperial College London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.387679.
Full textBooks on the topic "Tumour suppressor"
The oncogene and tumour suppressor gene factsbook. 2nd ed. San Diego, Calif: Academic Press, 1997.
Find full textPhillips, Stewart Mark Anthony. The loss of tumour suppressor genes in prostate cancer. Birmingham: University of Birmingham, 1995.
Find full textLecane, Philip Sidney. A study of the p53 tumour suppressor gene in adenovirus transformed human cells. Birmingham: University of Birmingham, 1995.
Find full textTammemagi, Martin Carl. Tobacco smoking, p53 tumour suppressor gene alterations, and clinicopathologic features and prognosis in non-small cell lung cancer. Ottawa: National Library of Canada = Bibliothèque nationale du Canada, 1998.
Find full textEl-Deiry, Wafik S. Tumor Suppressor Genes. New Jersey: Humana Press, 2003. http://dx.doi.org/10.1385/1592593283.
Full textEl-Deiry, Wafik S. Tumor Suppressor Genes. New Jersey: Humana Press, 2003. http://dx.doi.org/10.1385/1592593291.
Full textS, El-Deiry Wafik, ed. Tumor suppressor genes. Totowa, N.J: Humana Press, 2003.
Find full textRangnekar, Vivek M., ed. Tumor Suppressor Par-4. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-80558-6.
Full textRangnekar, Vivek M., ed. Tumor Suppressor Par-4. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-73572-2.
Full textMacdonald, F. Oncogenes and tumor suppressor genes. Oxford: Bios Scientific Publishers, 1991.
Find full textBook chapters on the topic "Tumour suppressor"
Lane, D. P., C. Midgley, and T. Hupp. "Tumour suppressor genes and molecular chaperones." In Molecular Chaperones, 113–17. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-2108-8_14.
Full textPiris, Miguel A., Juan C. Martinez, Margarita Sanchez-Beato, Juan F. Garcia, Carmen Bellas, Javier Menarguez, Raquel Villuendas, and Emilia Lloret. "Tumour Suppressor Genes in Hodgkin’s Disease." In Etiology of Hodgkin’s Disease, 209–22. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4613-0339-8_17.
Full textHollywood, D. P., and N. R. Lemoine. "Growth Factors, Oncogenes and Tumour Suppressor Genes." In Assessment of Cell Proliferation in Clinical Practice, 27–43. Tokyo: Springer Japan, 1992. http://dx.doi.org/10.1007/978-4-431-68287-5_2.
Full textEvan, Gerard, Trevor Littlewood, David Hancock, Martin Bennett, Elizabeth Harrington, and Abdallah Fanidi. "C-MYC: Oncogene and Tumour Suppressor Gene." In Apoptosis, 63–84. Boston, MA: Springer US, 1994. http://dx.doi.org/10.1007/978-1-4757-9217-1_5.
Full textHollywood, D. P., and N. R. Lemoine. "Growth Factors, Oncogenes and Tumour Suppressor Genes." In Assessment of Cell Proliferation in Clinical Practice, 27–43. London: Springer London, 1992. http://dx.doi.org/10.1007/978-1-4471-3190-8_2.
Full textLefebvre, Karen J., Sarah Assadian, Wissal El-Assaad, and Jose G. Teodoro. "Regulation of Angiogenesis by Tumour Suppressor Pathways." In Experimental and Clinical Metastasis, 79–99. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-3685-0_8.
Full textSherbet, G. V., and M. S. Lakshmi. "Tumour suppressor genes." In The Genetics of Cancer, 171–82. Elsevier, 1997. http://dx.doi.org/10.1016/b978-012639875-5/50013-3.
Full textHesketh, Robin. "Tumour Suppressor Genes." In The Oncogene & Tumour Suppressor Gene Factsbook, 26–30. Elsevier, 1997. http://dx.doi.org/10.1016/b978-012344548-3/50005-4.
Full textTavassoli, Mahvash, and Francesco Pezzella. "Oncogenesis and tumour suppression." In Oxford Textbook of Cancer Biology, edited by Francesco Pezzella, Mahvash Tavassoli, and David J. Kerr, 136–54. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780198779452.003.0011.
Full textHesketh, Robin. "Tumour Suppressor Genes Detected in Human Tumours." In The Oncogene & Tumour Suppressor Gene Factsbook, 83–85. Elsevier, 1997. http://dx.doi.org/10.1016/b978-012344548-3/50015-7.
Full textConference papers on the topic "Tumour suppressor"
Dawoud, M., M. Dawoud, D. Jones, K. Hodivala-Dilke, S. Dreger, C. Chelala, N. Asaad, and L. Jones. "Microenvironmental Changes in DCIS: Myoepithelial Cells Change from Tumour Suppressor to Tumour Promoter." In Abstracts: Thirty-Second Annual CTRC‐AACR San Antonio Breast Cancer Symposium‐‐ Dec 10‐13, 2009; San Antonio, TX. American Association for Cancer Research, 2009. http://dx.doi.org/10.1158/0008-5472.sabcs-09-4161.
Full textBlagih, J., A. Hock, S. Mason, F. Zani, K. Blyth, and K. Vousden. "PO-403 The tumour suppressor P53 as a guardian of immune tolerance and suppression." In Abstracts of the 25th Biennial Congress of the European Association for Cancer Research, Amsterdam, The Netherlands, 30 June – 3 July 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/esmoopen-2018-eacr25.914.
Full textBazzichetto, C., F. Conciatori, I. Falcone, F. Cognetti, L. Ciuffreda, and M. Milella. "PO-293 Tumour/stroma interactions in colorectal cancer (CRC) models: role of the tumour suppressor PTEN." In Abstracts of the 25th Biennial Congress of the European Association for Cancer Research, Amsterdam, The Netherlands, 30 June – 3 July 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/esmoopen-2018-eacr25.807.
Full textOrság, Petr, Hana Pivoňková, Medard Plucnara, Petra Horáková, and Miroslav Fojta. "Recognition of 7-deazapurine-substituted binding sites by tumour suppressor p53 protein." In XVth Symposium on Chemistry of Nucleic Acid Components. Prague: Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2011. http://dx.doi.org/10.1135/css201112427.
Full textKünzler, P., CA Seemayer, S. Kuchen, M. Neidhart, M. Pruschy, BA Michel, RE Gay, and S. Gay. "THU0104 In vivoandin vitroinvestigations of the tumour suppressor p16 in rheumatoid arthritis." In Annual European Congress of Rheumatology, Annals of the rheumatic diseases ARD July 2001. BMJ Publishing Group Ltd and European League Against Rheumatism, 2001. http://dx.doi.org/10.1136/annrheumdis-2001.981.
Full textRussell, RA, E. Dunlop, and A. Tee. "PO-102 Understanding the role of the tumour suppressor, FLCN, in renal tumorigenesis." In Abstracts of the 25th Biennial Congress of the European Association for Cancer Research, Amsterdam, The Netherlands, 30 June – 3 July 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/esmoopen-2018-eacr25.143.
Full textFurlan, T., K. Sana, J. Guenther, AV Nguyen, and J. Troppmair. "PO-217 Tumour suppressor function of the oxidoreductase p66Shc in BRAFV600E-transformed cells." In Abstracts of the 25th Biennial Congress of the European Association for Cancer Research, Amsterdam, The Netherlands, 30 June – 3 July 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/esmoopen-2018-eacr25.252.
Full textJaniszewska, J., M. Bodnar, M. Kostrzewska-Poczekaj, K. Bednarek, J. Paczkowska, R. Greenam, K. Szyfter, M. Wierzbicka, M. Jarmuz-Szymczak, and M. Giefing. "PO-380 Epigenetically regulated MAF is a new potential tumour suppressor gene in LSCC." In Abstracts of the 25th Biennial Congress of the European Association for Cancer Research, Amsterdam, The Netherlands, 30 June – 3 July 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/esmoopen-2018-eacr25.408.
Full textImoto, Issei, Shigeo Haruki, Ken-ich Kozaki, Takeshi Matsui, Hiroshi Kawachi, Shuhei Komatsu, Tomoki Muramatsu, Yutaka Shimada, Tatsuyuki Kawano, and Johji Inazawa. "Abstract 3071: Frequent silencing ofprotocadherin 17, a candidate tumour suppressor for esophageal squamous-cell carcinoma." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-3071.
Full textYouness, R., R. Assal, M. Gad, and A. Abdel Motaal. "PO-352 Hijacking hepatocellular carcinoma (HCC) tumour progression through restoring TP53/miR-15a/miR-16 tumour suppressor axis by a novel quercetin glycoside." In Abstracts of the 25th Biennial Congress of the European Association for Cancer Research, Amsterdam, The Netherlands, 30 June – 3 July 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/esmoopen-2018-eacr25.382.
Full textReports on the topic "Tumour suppressor"
Swafford, D. S., J. Tesfaigzi, and S. A. Belinsky. Expression of the p16{sup INK4a} tumor suppressor gene in rodent lung tumors. Office of Scientific and Technical Information (OSTI), December 1995. http://dx.doi.org/10.2172/381388.
Full textShyam, E., and P. Reddy. Tumor Suppressors and Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, October 2001. http://dx.doi.org/10.21236/ada403397.
Full textShyam, E., and P. Reddy. Tumor Suppressors and Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, October 2002. http://dx.doi.org/10.21236/ada412779.
Full textZeremski, Marija. Use of Genetic Suppressor Elements to Identify Potential Breast Tumor Suppressor Genes. Fort Belvoir, VA: Defense Technical Information Center, October 1999. http://dx.doi.org/10.21236/ada384064.
Full textFreeman, Michael. SIRT3 is a Mitochondrial Tumor Suppressor and Genetic Loss Results in a Murine Model for ER/PR-Positive Mammary Tumors Connecting Metabolism and Carcinogenesis Mitochondrial Tumor Suppressor. Revision. Fort Belvoir, VA: Defense Technical Information Center, November 2013. http://dx.doi.org/10.21236/ada604003.
Full textYu, Xiaochun. Characterize RAP80, a Potential Tumor Suppressor Gene. Fort Belvoir, VA: Defense Technical Information Center, April 2008. http://dx.doi.org/10.21236/ada485136.
Full textYu, Xiaochun. Characterize RAP80, a Potential Tumor Suppressor Gene. Fort Belvoir, VA: Defense Technical Information Center, April 2009. http://dx.doi.org/10.21236/ada520785.
Full textTomoda, Toshifumi, and Michael E. Barish. Novel Role of Merlin Tumor Suppressor in Autophagy and its Implication in Treating NF2-Associated Tumors. Fort Belvoir, VA: Defense Technical Information Center, April 2014. http://dx.doi.org/10.21236/ada608945.
Full textTomoda, Toshifumi, Jr Jhung, Hirota Donald, and Yuki. Novel Role of Merlin Tumor Suppressor in Autophagy and its Implication in Treating NF2-Associated Tumors. Fort Belvoir, VA: Defense Technical Information Center, April 2012. http://dx.doi.org/10.21236/ada563285.
Full textBarish, Michael E., Toshifumi Tomoda, Akiko Sumitomo, and Yuki Hirota. Novel Role of Merlin Tumor Suppressor in Autophagy and its Implication in Treating NF2-Associated Tumors. Fort Belvoir, VA: Defense Technical Information Center, April 2013. http://dx.doi.org/10.21236/ada592192.
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