Journal articles on the topic 'Tumour-promoting stroma'
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Tone, Tatjana, Elīna Tauvēna, Ilze Štrumfa, and Jānis Gardovskis. "Inflammatory Cells in Gastric Cancer: Promoting the Tumour or Protecting the Host?" Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences. 74, no. 2 (April 1, 2020): 111–17. http://dx.doi.org/10.2478/prolas-2020-0018.
Full textSeufferlein, Thomas, Michel Ducreux, Manuel Hidalgo, Gerald Prager, and Eric Van Cutsem. "More than a Gel & Hyaluronic Acid, a Central Component in the Microenvironment of Pancreatic Cancer." European Oncology & Haematology 14, no. 1 (2018): 40. http://dx.doi.org/10.17925/eoh.2018.14.1.40.
Full textKetteler, Julia, Andrej Panic, Henning Reis, Alina Wittka, Patrick Maier, Carsten Herskind, Ernesto Yagüe, Verena Jendrossek, and Diana Klein. "Progression-Related Loss of Stromal Caveolin 1 Levels Mediates Radiation Resistance in Prostate Carcinoma via the Apoptosis Inhibitor TRIAP1." Journal of Clinical Medicine 8, no. 3 (March 12, 2019): 348. http://dx.doi.org/10.3390/jcm8030348.
Full textElisha, Yair, Yael Sagi, Georg Klein, Ravid Straussman, and Benjamin Geiger. "Cooperativity between stromal cytokines drives the invasive migration of human breast cancer cells." Philosophical Transactions of the Royal Society B: Biological Sciences 374, no. 1779 (July 2019): 20180231. http://dx.doi.org/10.1098/rstb.2018.0231.
Full textMaeda, Masahiro, Hideyuki Takeshima, Naoko Iida, Naoko Hattori, Satoshi Yamashita, Hiroshi Moro, Yoshimi Yasukawa, et al. "Cancer cell niche factors secreted from cancer-associated fibroblast by loss of H3K27me3." Gut 69, no. 2 (May 13, 2019): 243–51. http://dx.doi.org/10.1136/gutjnl-2018-317645.
Full textLeonard, Niamh A., Eileen Reidy, Kerry Thompson, Emma McDermott, Eleonora Peerani, Elena Tomas Bort, Frances R. Balkwill, Daniela Loessner, and Aideen E. Ryan. "Stromal Cells Promote Matrix Deposition, Remodelling and an Immunosuppressive Tumour Microenvironment in a 3D Model of Colon Cancer." Cancers 13, no. 23 (November 29, 2021): 5998. http://dx.doi.org/10.3390/cancers13235998.
Full textSpunde, Karina, Ksenija Korotkaja, and Anna Zajakina. "Recombinant Viral Vectors for Therapeutic Programming of Tumour Microenvironment: Advantages and Limitations." Biomedicines 10, no. 9 (August 31, 2022): 2142. http://dx.doi.org/10.3390/biomedicines10092142.
Full textPetrella, Francesco, Isabella Rimoldi, Stefania Rizzo, and Lorenzo Spaggiari. "Mesenchymal Stromal Cells for Antineoplastic Drug Loading and Delivery." Medicines 4, no. 4 (November 23, 2017): 87. http://dx.doi.org/10.3390/medicines4040087.
Full textSevenich, Lisa, Robert L. Bowman, Steven D. Mason, Daniela F. Quail, Franck Rapaport, Benelita T. Elie, Edi Brogi, et al. "Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S." Nature Cell Biology 16, no. 9 (August 3, 2014): 876–88. http://dx.doi.org/10.1038/ncb3011.
Full textRIPPMANN, Jörg F., Klaus PFIZENMAIER, Ralf MATTES, Wolfgang J. RETTIG, and Dieter MOOSMAYER. "Fusion of the tissue factor extracellular domain to a tumour stroma specific single-chain fragment variable antibody results in an antigen-specific coagulation-promoting molecule." Biochemical Journal 349, no. 3 (July 25, 2000): 805–12. http://dx.doi.org/10.1042/bj3490805.
Full textBalaziova, Eva, Petr Vymola, Petr Hrabal, Rosana Mateu, Michal Zubal, Robert Tomas, David Netuka, et al. "Fibroblast Activation Protein Expressing Mesenchymal Cells Promote Glioblastoma Angiogenesis." Cancers 13, no. 13 (July 1, 2021): 3304. http://dx.doi.org/10.3390/cancers13133304.
Full textBryce, Adam S., Stephan B. Dreyer, Fieke E. M. Froeling, and David K. Chang. "Exploring the Biology of Cancer-Associated Fibroblasts in Pancreatic Cancer." Cancers 14, no. 21 (October 28, 2022): 5302. http://dx.doi.org/10.3390/cancers14215302.
Full textPatras, Laura, Marcel H. A. M. Fens, Pieter Vader, Arjan Barendrecht, Alina Sesarman, Manuela Banciu, and Raymond Schiffelers. "Normoxic Tumour Extracellular Vesicles Modulate the Response of Hypoxic Cancer and Stromal Cells to Doxorubicin In Vitro." International Journal of Molecular Sciences 21, no. 17 (August 19, 2020): 5951. http://dx.doi.org/10.3390/ijms21175951.
Full textLutzny, Gloria, Zhoulei Li, Madlen Oelsner, Jolanta Slawska, Thomas Kocher, Alexander Egle, Christian Peschel, Ulrich Keller, and Ingo Ringshausen. "Proteinkinase C-β Inhibitors Mitigate Microenvironment-Mediated Survival Of CLL Cells and Sensitise Malignant B Cells To Cytotoxic Drugs." Blood 122, no. 21 (November 15, 2013): 669. http://dx.doi.org/10.1182/blood.v122.21.669.669.
Full textBruns, Heiko, Dimitrios Mougiakakos, Mario Fabri, Shirin Pasemann, Regina Jitschin, Kerstin Amann, Maike Büttner, Andreas Mackensen, and Armin Gerbitz. "Vitamin D Triggers Killing of Burkitt Lymphoma Cells by Human Macrophages." Blood 120, no. 21 (November 16, 2012): 1035. http://dx.doi.org/10.1182/blood.v120.21.1035.1035.
Full textHaselager, Marco, Eduard Perelaer, Arnon P. Kater, and Eric Eldering. "Development of a Novel Lymph Node-Based 3D Culture System Promoting Chronic Lymphocytic Leukemia Proliferation and Survival." Blood 136, Supplement 1 (November 5, 2020): 47–48. http://dx.doi.org/10.1182/blood-2020-141962.
Full textWebber, J. P., L. K. Spary, A. J. Sanders, R. Chowdhury, W. G. Jiang, R. Steadman, J. Wymant, et al. "Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes." Oncogene 34, no. 3 (January 20, 2014): 290–302. http://dx.doi.org/10.1038/onc.2013.560.
Full textNeesse, Albrecht, Christian Alexander Bauer, Daniel Öhlund, Matthias Lauth, Malte Buchholz, Patrick Michl, David A. Tuveson, and Thomas M. Gress. "Stromal biology and therapy in pancreatic cancer: ready for clinical translation?" Gut 68, no. 1 (September 3, 2018): 159–71. http://dx.doi.org/10.1136/gutjnl-2018-316451.
Full textQuattrone, Anna, Barbara Dewaele, Agnieszka Wozniak, Marijke Bauters, Vanessa Vanspauwen, Giuseppe Floris, Patrick Schöffski, et al. "Promoting role of cholecystokinin 2 receptor (CCK2R) in gastrointestinal stromal tumour pathogenesis." Journal of Pathology 228, no. 4 (September 28, 2012): 565–74. http://dx.doi.org/10.1002/path.4071.
Full textMorgan, Jonathan J., Roisin M. McAvera, and Lisa J. Crawford. "TRAF6 Silencing Attenuates Multiple Myeloma Cell Adhesion to Bone Marrow Stromal Cells." International Journal of Molecular Sciences 20, no. 3 (February 6, 2019): 702. http://dx.doi.org/10.3390/ijms20030702.
Full textToledo, Belén, Manuel Picon-Ruiz, Juan Antonio Marchal, and Macarena Perán. "Dual Role of Fibroblasts Educated by Tumour in Cancer Behavior and Therapeutic Perspectives." International Journal of Molecular Sciences 23, no. 24 (December 8, 2022): 15576. http://dx.doi.org/10.3390/ijms232415576.
Full textRoninson, Igor B. "Oncogenic functions of tumour suppressor p21Waf1/Cip1/Sdi1: association with cell senescence and tumour-promoting activities of stromal fibroblasts." Cancer Letters 179, no. 1 (May 2002): 1–14. http://dx.doi.org/10.1016/s0304-3835(01)00847-3.
Full textAkerman, Anouschka, George Sharbeen, Jeff Holst, Janet Youkhana, Joshua McCarroll, David Goldstein, Mert Erkan, and Phoebe Phillips. "Targeting a solute carrier to metabolically reprogram tumour-promoting stromal cells in pancreatic cancer." Pancreatology 18, no. 4 (June 2018): S156. http://dx.doi.org/10.1016/j.pan.2018.05.419.
Full textEgan, Hannah, Oliver Treacy, Kevin Lynch, Niamh Leonard, Amir Nader, Margaret Sheehan, Sean Hynes, et al. "865 Sugar high: Does the sialic acid profile of cancer-associated fibroblasts induce a more tumour-permissive microenvironment?" Journal for ImmunoTherapy of Cancer 8, Suppl 3 (November 2020): A918. http://dx.doi.org/10.1136/jitc-2020-sitc2020.0865.
Full textPeta, Kimberly Thando, Melvin Anyasi Ambele, and Michael Sean Pepper. "Similarities between Tumour Immune Response and Chronic Wound Microenvironment: Influence of Mesenchymal Stromal/Stem Cells." Journal of Immunology Research 2021 (March 29, 2021): 1–11. http://dx.doi.org/10.1155/2021/6649314.
Full textGadea, Bedrick B., and Johanna A. Joyce. "Tumour–host interactions: implications for developing anti-cancer therapies." Expert Reviews in Molecular Medicine 8, no. 30 (December 2006): 1–32. http://dx.doi.org/10.1017/s1462399406000172.
Full textPereira, Joana F. S., Cláudia Bessa, Paulo Matos, and Peter Jordan. "Pro-Inflammatory Cytokines Trigger the Overexpression of Tumour-Related Splice Variant RAC1B in Polarized Colorectal Cells." Cancers 14, no. 6 (March 9, 2022): 1393. http://dx.doi.org/10.3390/cancers14061393.
Full textBianchini, Francesca, Elisa Giannoni, Sergio Serni, Paola Chiarugi, and Lido Calorini. "22 : 6n-3 DHA inhibits differentiation of prostate fibroblasts into myofibroblasts and tumorigenesis." British Journal of Nutrition 108, no. 12 (March 6, 2012): 2129–37. http://dx.doi.org/10.1017/s0007114512000359.
Full textAl-Akkad, Walid, Pilar Acedo, Maria-Giovanna Vilia, Luca Frenguelli, Alexander Ney, Irene Rodriguez-Hernandez, Peter L. Labib, et al. "Tissue-Specific Human Extracellular Matrix Scaffolds Promote Pancreatic Tumour Progression and Chemotherapy Resistance." Cells 11, no. 22 (November 17, 2022): 3652. http://dx.doi.org/10.3390/cells11223652.
Full textPancione, Massimo, Guido Giordano, Andrea Remo, Antonio Febbraro, Lina Sabatino, Erminia Manfrin, Michele Ceccarelli, and Vittorio Colantuoni. "Immune Escape Mechanisms in Colorectal Cancer Pathogenesis and Liver Metastasis." Journal of Immunology Research 2014 (2014): 1–11. http://dx.doi.org/10.1155/2014/686879.
Full textLeonard, Niamh, Oliver Treacy, Hannah Egan, Grace O’Malley, Elena Tomas Bort, Eleonora Peerani, Thomas Ritter, Daniela Loessner, Laurence Egan, and Aideen Ryan. "864 The mesenchymal stromal compartment in colorectal cancer greatly alters the innate tumour immune microenvironment both in 2D and 3D culture systems." Journal for ImmunoTherapy of Cancer 8, Suppl 3 (November 2020): A917. http://dx.doi.org/10.1136/jitc-2020-sitc2020.0864.
Full textCiarletta, P., L. Foret, and M. Ben Amar. "The radial growth phase of malignant melanoma: multi-phase modelling, numerical simulations and linear stability analysis." Journal of The Royal Society Interface 8, no. 56 (July 23, 2010): 345–68. http://dx.doi.org/10.1098/rsif.2010.0285.
Full textAlhussan, Abdulaziz, Nicholas Palmerley, Julian Smazynski, Joanna Karasinska, Daniel J. Renouf, David F. Schaeffer, Wayne Beckham, Abraham S. Alexander, and Devika B. Chithrani. "Potential of Gold Nanoparticle in Current Radiotherapy Using a Co-Culture Model of Cancer Cells and Cancer Associated Fibroblast Cells." Cancers 14, no. 15 (July 22, 2022): 3586. http://dx.doi.org/10.3390/cancers14153586.
Full textMelaccio, Assunta, Antonia Reale, Ilaria Saltarella, Vanessa Desantis, Aurelia Lamanuzzi, Sebastiano Cicco, Maria Antonia Frassanito, Angelo Vacca, and Roberto Ria. "Pathways of Angiogenic and Inflammatory Cytokines in Multiple Myeloma: Role in Plasma Cell Clonal Expansion and Drug Resistance." Journal of Clinical Medicine 11, no. 21 (November 1, 2022): 6491. http://dx.doi.org/10.3390/jcm11216491.
Full textSammarco, Giuseppe, Gilda Varricchi, Valentina Ferraro, Michele Ammendola, Michele De Fazio, Donato Francesco Altomare, Maria Luposella, et al. "Mast Cells, Angiogenesis and Lymphangiogenesis in Human Gastric Cancer." International Journal of Molecular Sciences 20, no. 9 (April 29, 2019): 2106. http://dx.doi.org/10.3390/ijms20092106.
Full textGodlewski, Janusz, and Zbigniew Kmiec. "Colorectal Cancer Invasion and Atrophy of the Enteric Nervous System: Potential Feedback and Impact on Cancer Progression." International Journal of Molecular Sciences 21, no. 9 (May 11, 2020): 3391. http://dx.doi.org/10.3390/ijms21093391.
Full textSteiro, Ida, Pegah Abdollahi, Magne Børset, and Tobias S. Slørdahl. "The Serine Protease Matriptase Acts As a Tumour Suppressor in Multiple Myeloma." Blood 136, Supplement 1 (November 5, 2020): 14. http://dx.doi.org/10.1182/blood-2020-140229.
Full textSalati, Massimiliano, Francesco Caputo, Andrea Spallanzani, Fabio Gelsomino, Beatrice Ricco', Gabriele Luppi, Luca Reggiani Bonetti, et al. "Clinicopathologic correlates and prognostic relevance of the immune checkpoint CD73 (NT5E) in resected biliary cancers (BC)." Journal of Clinical Oncology 40, no. 4_suppl (February 1, 2022): 473. http://dx.doi.org/10.1200/jco.2022.40.4_suppl.473.
Full textCarpenter, Ben, Sara Ghorashian, Emma Nicholson, James Edward Griffin, Maryam Ahmadi, Angelika Holler, Barry Flutter, et al. "Targeting Therapeutic T Cells to Tumour Niches." Blood 120, no. 21 (November 16, 2012): 3009. http://dx.doi.org/10.1182/blood.v120.21.3009.3009.
Full textGoh, Sal Lee, Jean-Pierre Levesque, Allison R. Petitt, Valarie Barbier, and Ingrid G. Winkler. "Therapeutic Blockade of Macrophage Colony Stimulating Factor (CSF-1) Delays AML Progression in Mice In Vivo." Blood 128, no. 22 (December 2, 2016): 2835. http://dx.doi.org/10.1182/blood.v128.22.2835.2835.
Full textCrassini, Kyle R., Yandong Shen, William S. Stevenson, Stephen P. Mulligan, Oliver Giles Best, and Richard Christopherson. "mRNA Profiling of CLL Cells Derived from the Blood, Bone Marrow and Lymph Node." Blood 132, Supplement 1 (November 29, 2018): 1850. http://dx.doi.org/10.1182/blood-2018-99-118264.
Full textCuthill, Kirsty M., Andrea Gail Sherman Buggins, Pj Chana, and Stephen Devereux. "Targeting The T Cell Component Of The Tumour Microenvironment In Chronic Lymphocytic Leukaemia; A Potential Therapeutic Strategy." Blood 122, no. 21 (November 15, 2013): 4147. http://dx.doi.org/10.1182/blood.v122.21.4147.4147.
Full textReidy, Mairead, Marianne VanDijk, Michael O'Neill, and Michael O'Dwyer. "The Dual PIM/PI3-K Inhibitor Ibl-202 Overcomes Microenvironmental Mediated Resistance in Multiple Myeloma and Prevents PIM1 Induced CXCR4 Upregulation." Blood 126, no. 23 (December 3, 2015): 5350. http://dx.doi.org/10.1182/blood.v126.23.5350.5350.
Full textKovács, Dávid, Nóra Igaz, Annamária Marton, Andrea Rónavári, Péter Bélteky, László Bodai, Gabriella Spengler, et al. "Core–shell nanoparticles suppress metastasis and modify the tumour-supportive activity of cancer-associated fibroblasts." Journal of Nanobiotechnology 18, no. 1 (January 21, 2020). http://dx.doi.org/10.1186/s12951-020-0576-x.
Full textHan, Xuexiang, Yiye Li, Ying Xu, Xiao Zhao, Yinlong Zhang, Xiao Yang, Yongwei Wang, et al. "Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem." Nature Communications 9, no. 1 (August 23, 2018). http://dx.doi.org/10.1038/s41467-018-05906-x.
Full textChen, Jing-Yi, Chien-Feng Li, You-Syuan Lai, and Wen-Chun Hung. "Lysine demethylase 2A expression in cancer-associated fibroblasts promotes breast tumour growth." British Journal of Cancer, October 7, 2020. http://dx.doi.org/10.1038/s41416-020-01112-z.
Full textMurphy, Kendelle J., Jessie Zhu, Michael Trpceski, Brooke A. Pereira, Paul Timpson, and David Herrmann. "Focal adhesion kinase priming in pancreatic cancer, altering biomechanics to improve chemotherapy." Biochemical Society Transactions, August 5, 2022. http://dx.doi.org/10.1042/bst20220162.
Full textKay, Emily J., Grigorios Koulouras, and Sara Zanivan. "Regulation of Extracellular Matrix Production in Activated Fibroblasts: Roles of Amino Acid Metabolism in Collagen Synthesis." Frontiers in Oncology 11 (August 27, 2021). http://dx.doi.org/10.3389/fonc.2021.719922.
Full textShams, Anwar. "Re-evaluation of the myoepithelial cells roles in the breast cancer progression." Cancer Cell International 22, no. 1 (December 12, 2022). http://dx.doi.org/10.1186/s12935-022-02829-y.
Full textTakahashi, Masahide, Hiroki Kobayashi, Yasuyuki Mizutani, Akitoshi Hara, Tadashi Iida, Yuki Miyai, Naoya Asai, and Atsushi Enomoto. "Roles of the Mesenchymal Stromal/Stem Cell Marker Meflin/Islr in Cancer Fibrosis." Frontiers in Cell and Developmental Biology 9 (October 5, 2021). http://dx.doi.org/10.3389/fcell.2021.749924.
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