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Academic literature on the topic 'Tumors Measurement'

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Published: 10 December 2022
Last updated: 28 January 2023

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Journal articles on the topic "Tumors Measurement"

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Putri, Maizza Nadia, Kusworo Adi, M.Irwan Katili, Sidin Hariyanto, and Dwi Rochmayanti. "COMPARISON MEASUREMENT AND CALCULATION OF BRAIN TUMOR IN MRI MODALITIES UTILISING SPIN-ECHO PULSE SEQUENCE T1-WEIGHTED CONTRAST AND DIGITAL IMAGE PROCESSING APPLICATIONS." Journal of Vocational Health Studies 6, no. 2 (November 1, 2022): 151–57. http://dx.doi.org/10.20473/jvhs.v6.i2.2022.151-157.

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Background: Evaluation of brain tumor MRI image results performed by radiologists employing the linear measurement method has several weaknesses and is sensitive to subjectivity. Purpose: To compare the results of measurements and calculations of brain tumors utilizing the linear measurement method on the Siemens 1.5 Tesla MRI modality employing pulse sequence spin echo with T1 contrast weighting compared with the results of measurements and calculations of brain tumors utilizing the active contour segmentation method. Method: An experimental study was conducted on 32 MRI images. Result: The study’s findings indicated that the linear measurement was more significant than the active contour segmentation method (p-value<0,05). The results were obtained by calculating the sensitivity and specificity values of the diagnostic test, which were calculated to be 87.5%. Conclusion: The active contour segmentation method applied to pulse sequence spin-echo T1-weighted contrast can be utilized as an alternative measurement and calculation of brain tumors with a sensitivity and specificity value of 87.5%. Further research suggests developing a Matlab application to compare the results of measurements and calculations of brain tumors on acquiring 3D image magnetic resonance imaging data.
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Ferrari, L., E. Seregni, A. Martinetti, B. Van Graafeiland, S. Nerini-Molteni, C. Botti, S. Artale, S. Cresta, and E. Bombardieri. "Chromogranin a Measurement in Neuroendocrine Tumors." International Journal of Biological Markers 13, no. 1 (January 1998): 3–9. http://dx.doi.org/10.1177/172460089801300102.

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Neuroendocrine tumors (NETs) are rare neoplasms characterized by a low proliferative index and, in some cases, a favorable prognosis. These tumors often overproduce and release biologically active substances that are responsible for severe syndromes. Tumor marker measurement provides the clinician with useful information for the management of NET patients. The substances released by overproducing tumors are currently used as biomarkers, but there is a need for sensitive markers also for the “biochemically silent” NETs. The most effective and reliable blood marker available today is chromogranin A (CgA). Because of its high sensitivity and specificity, this glycoprotein can be used for the diagnosis, prognosis and follow-up of NETs. Furthermore, CgA measurement can be used for monitoring those tumors not overproducing or releasing any hormones or biological amines. This paper is a synthetic review on the value of CgA in NET management and reports our experiences with CgA measurement in NET patients.
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Erasmus, Jeremy J., Gregory W. Gladish, Lyle Broemeling, Bradley S. Sabloff, Mylene T. Truong, Roy S. Herbst, and Reginald F. Munden. "Interobserver and Intraobserver Variability in Measurement of Non–Small-Cell Carcinoma Lung Lesions: Implications for Assessment of Tumor Response." Journal of Clinical Oncology 21, no. 13 (July 1, 2003): 2574–82. http://dx.doi.org/10.1200/jco.2003.01.144.

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Purpose: Response of solid malignancies to therapy is usually determined by serial measurements of tumor size. The purpose of our study was to assess the consistency of measurements performed by readers evaluating lung tumors. Materials and Methods: The study group was composed of 33 patients with lung tumors more than 1.5 cm. Bidimensional (BD) and unidimensional (UD) measurements were performed on computed tomography (CT) scans according to the World Health Organization (WHO) criteria and the Response Evaluation Criteria in Solid Tumors (RECIST), respectively. Measurements were performed independently by five thoracic radiologists using printed film and were repeated after 5 to 7 days. Inter- and intraobserver measurement variations were estimated through statistical modeling. Results: There were 40 tumors with an average size of 1.8 to 8.0 cm (mean, 4.1 cm). Analysis of variance showed a significant difference (P < .05) among readers and among the measured nodules for UD and BD measurements. Interobserver misclassification rates were more than intraobserver misclassification rates using either progressive disease or response criteria. The probability of misclassifying a tumor with the WHO criteria or RECIST was greatest with interobserver measurements when criteria for progression (43% BD, 30% UD) were used and lowest with intraobserver measurements when criteria for response (2.5% BD, 3.0% UD) were used. In addition, interobserver misclassification rates were more than intraobserver misclassification rates for both regular and irregular tumors. Conclusion: Measurements of lung tumor size on CT scans are often inconsistent and can lead to an incorrect interpretation of tumor response. Consistency can be improved if the same reader performs serial measurements for any one patient.
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Wustefeld-Janssens, Brandan G., Arathi Vinayak, Lindsay A. Parker, and Danielle L. Hollenbeck. "Quantification of Canine Apocrine Gland Anal Sac Adenocarcinoma (AGASACA) Tumor Specimen Shrinkage after Formalin Fixation." Animals 12, no. 15 (July 22, 2022): 1869. http://dx.doi.org/10.3390/ani12151869.

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The aim was to prospectively measure the shrinkage of primary apocrine gland anal sac adenocarcinoma (AGASACA) tumors after 24 and 48 h of formalin fixation. Dogs that were diagnosed with AGASACA pre-operatively by aspiration cytology were prospectively enrolled in the study. Tumor extirpation was performed in a closed technique. The tumor and associated tissues were examined on the back table away from the patient and the widest dimension of the tumor was measured using a sterile ruler (Medline®; Northfield, IL, USA). This measurement was recorded in mm (t0). The tissue was placed in 10% buffered formalin and stored at room temperature. Two further measurements were taken after 24 (t24) and 48 (t48) hours of formalin fixation. Once the 48 h measurement was taken, the tissue was submitted for histopathology. The percentage of shrinkage between time points was calculated by using the following equation: (1 − [time b/time a]) × 100. Overall, 23 dogs with 23 tumors were enrolled. The mean percentage of shrinkage after 24 and 48 h of formalin fixation was 4.8% and 7.2%, respectively. The median diameter of the tumors reduced by 1 mm over 48 h and was not significantly different at any time point. These data will aid clinicians in interpreting measurements of AGASACA tumors following formalin fixation and shows that minimal change in tumor size is expected following 48 h.
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Xu, Xiaohong, Liangping Luo, Jiexin Chen, Jiexin Wang, Honglian Zhou, Mingyi Li, Zhanqiang Jin, et al. "Acoustic Radiation Force Impulse Elastography for Efficacy Evaluation after Hepatocellular Carcinoma Radiofrequency Ablation: A Comparative Study with Contrast-Enhanced Ultrasound." BioMed Research International 2014 (2014): 1–7. http://dx.doi.org/10.1155/2014/901642.

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Aim. To explore acoustic radiation force impulse (ARFI) elastography in assessing residual tumors of hepatocellular carcinoma (HCC) after radiofrequency ablation (RFA).Materials and Methods. There were 83 HCC lesions among 72 patients. All patients were examined with ARFI, contrast enhanced ultrasound (CEUS), and CT or MRI. Tumor brightness on virtual touch tissue imaging (VTI) and shear wave velocity (SWV) were assessed before and approximately one month after RFA.Results. There were 14 residual tumors after RFA. VTI showed that all the tumors were darker after RFA. VTI was not able to distinguish the ablated lesions and the residual tumors. 13 residual tumor lesions were detected by CEUS. All completely ablated nodules had SWV demonstration of x.xx., while with those residual nodules, 6 tumors had x.xx measurement and 8 tumors had measurable SWV. nine lesions with residual tumors occurred in cirrhosis subjects and 5 lesions with residual tumors occurred in fibrosis subjects; there was no residual tumor in the normal liver subjects.Conclusion. VTI technique cannot demonstrate residual tumor post RFA. While SWV measurement of less than x.xx is likely associated with residual tumors, measurement of less than x.xx cannot exclude residual tumors. Liver cirrhosis is associated with decreased chance of a complete ablation.
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Anderson, Michael, Anna Moshnikova, Donald M. Engelman, Yana K. Reshetnyak, and Oleg A. Andreev. "Probe for the measurement of cell surface pH in vivo and ex vivo." Proceedings of the National Academy of Sciences 113, no. 29 (July 5, 2016): 8177–81. http://dx.doi.org/10.1073/pnas.1608247113.

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We have developed a way to measure cell surface pH by positioning a pH-sensitive fluorescent dye, seminaphtharhodafluor (SNARF), conjugated to the pH low insertion peptide (pHLIP). It has been observed that many diseased tissues are acidic and that tumors are especially so. A combination of effects acidifies tumor cell interiors, and cells pump out lactic acid and protons to maintain intracellular pH, acidifying the extracellular space. Overexpression of carbonic anhydrases on cell surfaces further contributes to acidification. Thus, the pH near tumor cell surfaces is expected to be low and to increase with distance from the membrane, so bulk pH measurements will not report surface acidity. Our new surface pH-measurement tool was validated in cancer cells grown in spheroids, in mouse tumor models in vivo, and in excised tumors. We found that the surface pH is sensitive to cell glycolytic activity: the pH decreases in high glucose and increases if glucose is replaced with nonmetabolized deoxyglucose. For highly metastatic cancer cells, the pH measured at the surface was 6.7–6.8, when the surrounding external pH was 7.4. The approach is sensitive enough to detect 0.2–0.3 pH unit changes in vivo in tumors induced by i.p. injection of glucose. The pH at the surfaces of highly metastatic cells within tumors was found to be about 6.1–6.4, whereas in nonmetastatic tumors, it was 6.7–6.9, possibly creating a way to distinguish more aggressive from less aggressive tumors. Other biological roles of surface acidity may be found, now that targeted measurements are possible.
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Gillies, R. J., Z. Liu, and Z. Bhujwalla. "31P-MRS measurements of extracellular pH of tumors using 3-aminopropylphosphonate." American Journal of Physiology-Cell Physiology 267, no. 1 (July 1, 1994): C195—C203. http://dx.doi.org/10.1152/ajpcell.1994.267.1.c195.

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The extracellular pH (pHex) of tumors is generally acidic. However, it is only recently that noninvasive magnetic resonance spectroscopic (MRS) measurements have determined that the intracellular pH (pHin) of tumor cells in situ is neutral or slightly alkaline compared with that of normal tissues. Thus cells in tumors maintain larger pH gradients than do cells in nontumor tissues. To date, measurements of pHex in tumors have been made using microelectrodes, which preclude measurement of pHex and pHin within the same preparation. In addition, microelectrodes are invasive and have the potential to alter the measured pH values. The present communication describes simultaneous measurement of pHex and pHin in vitro in bioreactor culture and in vivo using 31P-MRS analyses of 3-aminopropylphosphonate (3-APP) and inorganic phosphate. In vitro results indicate that 3-APP is not toxic and that its resonant frequency is sensitive to pH and not significantly affected by temperature or ionic strength. Bioreactor experiments indicate that this compound is neither internalized nor metabolized by cells. Experiments in vivo indicate that 3-APP can be administered intraperitoneally and that RIF-1 tumors maintain a steady-state pHin of 7.25 and a pHex of 6.66. These data have significance to basic tumor cell physiology and to the design of approaches to cancer chemotherapy and hyperthermic therapy, because both of these modalities exhibit pH sensitivity. It is also likely that these techniques will be applicable to localized MRS of other organ systems in vivo.
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Moats, Rex A., Sendhil Velan-Mullan, Russell Jacobs, Ignacio Gonzalez-Gomez, David J. Dubowitz, Takashi Taga, Vazgen Khankaldyyan, et al. "Micro-MRI at 11.7 T of a Murine Brain Tumor Model Using Delayed Contrast Enhancement." Molecular Imaging 2, no. 3 (July 1, 2003): 153535002003031. http://dx.doi.org/10.1162/15353500200303112.

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In vivo imaging methodologies allow for serial measurement of tumor size, circumventing the need for sacrificing mice at given time points. In orthotopically transplanted murine models of brain tumors, cross-section micro-MRI allows for visualization and measurement of the physically inaccessible tumors. To allow for long resident times of a contrast agent in the tumor, intraperitoneal administration was used as a route of injection for contrast-enhanced micro-MRI, and a simple method for relative tumor volume measurements was examined. A strategy for visualizing the variability of the delayed tumor enhancement was developed. These strategies were applied to monitor the growth of brain tumors xenotransplanted into nude mice and either treated with the antiangiogenic peptide EMD 121974 or an inactive control peptide. Each mouse was used as its own control. Serial imaging was done weekly, beginning at Day 7 after tumor cell implantation and continued for 7 weeks. Images obtained were reconstructed on the MRI instrument. The image files were transferred off line to be postprocessed to assess tumor growth (volume) and variability in enhancement (three-dimensional [3-D] intensity models). In a small study, tumor growth and response to treatment were followed using this methodology and the high-resolution images displayed in 3-D allowed for straightforward qualitative assessment of variable enhancement related to vascular factors and tumor age.
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Lapa, Constantin, Andreas Buck, Michael Lassmann, Rudolf Werner, and Heribert Hänscheid. "Absorbed dose estimates from a single measurement one to three days after the administration of 177Lu-DOTATATE/-TOC." Nuklearmedizin 56, no. 06 (2017): 219–24. http://dx.doi.org/10.3413/nukmed-0925-17-08.

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SummaryAim: To retrospectively analyze the accuracy of absorbed dose estimates from a single measurement of the activity concentrations in tumors and relevant organs one to three days after the administration of 177Lu-DOTA-TATE/TOC assuming tissue specific effective half-lives. Methods: Activity kinetics in 54 kidneys, 30 neuroendocrine tumor lesions, 25 livers, and 27 spleens were deduced from series of planar images in 29 patients. After adaptation of mono- or bi-exponential fit functions to the measured data, it was analyzed for each fit function how precise the time integral can be estimated from fixed tissue-specific half-lives and a single measurement at 24, 48, or 72 h after the administration. Results: For the kidneys, assuming a fixed tissue-specific half-life of 50 h, the deviations of the estimate from the actual integral were median (5 % percentile, 95 % percentile): -3 °% (-15 %>; +16 °%) for measurements after 24 h, +2 %> (-9 %>; +12 %>) for measurements after 48 h, and 0 % (-2 %; +12 %) for measurements after 72 h. The corresponding values for the other tissues, assuming fixed tissue-specific half-lives of 67 h for liver and spleen and 77 h for tumors, were +2 % (-25 %; +20 %) for measurements after 24 h, +2 °% (-16 %>; +17 %>) for measurements after 48 h, and +2 %> (-11 %>; +10 %>) for measurements after 72 h. Conclusions: Especially for the kidneys, which often represent the dose limiting organ, but also for liver, spleen, and neuroendocrine tumors, a meaningful absorbed dose estimate is possible from a single measurement after 2, more preferably 3 days after the administration of 177Lu-DOTA-TATE/-TOC assuming fixed tissue specific effective half-lives.
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Allakhverdieva, G. F., A. M. Mudunov, and A. F. Batsev. "Use of transoral ultrasonography technique in tongue cancer: Advantages and disadvantages." MD-Onco 2, no. 4 (December 14, 2022): 41–45. http://dx.doi.org/10.17650/2782-3202-2022-2-4-41-45.

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Aim. To evaluate advantages and disadvantages of transoral ultrasonography (US) in tongue cancer.Materials and methods. US was performed in 165 patients between the ages of 15 and 85 years with malignant tumors of the mobile tongue (74 (44.9 %) women, 91 (55.1 %) men).Among 165 patients, 144 had primary tongue tumor. The study also included 21 (12.7 %) patients with recurrent tumor which clinically could be represented by a true recurrence (tumor development 6 months after the end of treatment) or by continued growth (tumor development less than 6 months after the end of treatment). The study included patients with tongue tumors Т1 - 50 (30.3 %) patients, Т2 - 78 (47.3 %) patients, Т3 - 16.4 % of patients, Т4 - 6.1 % of patients.Three types of approach to tongue tumor visualization were used: submandibular, transoral, and transbuccal with a standard linear transducer (4-9 MHz) and intraoperative linear transducer (5-14 MHz). In total in 165 patients with tongue tumors, 147 (89.1 %) transoral US, 86 (52.1 %) submandibular US and 25 (15.2 %) transbuccal US examinations were performed.Results. Among 165 patients, agreement between the sizes measured using US and histological examination was observed in 142 (86.1 %) patients taking into account 15 % error.With increasing tumor thickness and, correspondingly, T criterion, increased frequency of agreement between US data and histological data was observed. Thus, for T1 stage frequency of agreement with US data was observed in 61.8 % of cases, for Т2 stage in 81.1 % of cases, for Т3 stage in 93.8 %, and for Т4 stage agreement was observed in 100 % of cases.Frequency of agreement with histological data in evaluation of tongue tumor thickness for transoral approach was significantly higher than for submandibular approach (р = 0.014). Transoral technique was more accurate for measurement of thickness of primary tumors - 80.3 % of results agreed with histological examination, and for recurrences frequency of agreement was only 33.3 %. Submandibular approach for primary tumors showed accurate measurements only in 67.6 % of cases, in recurrent tumors in 58.3 % of cases. Transbuccal approach also showed higher measurement accuracy for tumor thickness in primary patients (70.0 %) compared to recurrent tumors (40.0 %).Conclusion. Use of transoral ultrasonography significantly improves clinical staging of tongue tumors at the preoperative stage.
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Dissertations / Theses on the topic "Tumors Measurement"

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Verleyen, Wim. "Machine learning for systems pathology." Thesis, University of St Andrews, 2013. http://hdl.handle.net/10023/4512.

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Systems pathology attempts to introduce more holistic approaches towards pathology and attempts to integrate clinicopathological information with “-omics” technology. This doctorate researches two examples of a systems approach for pathology: (1) a personalized patient output prediction for ovarian cancer and (2) an analytical approach differentiates between individual and collective tumour invasion. During the personalized patient output prediction for ovarian cancer study, clinicopathological measurements and proteomic biomarkers are analysed with a set of newly engineered bioinformatic tools. These tools are based upon feature selection, survival analysis with Cox proportional hazards regression, and a novel Monte Carlo approach. Clinical and pathological data proves to have highly significant information content, as expected; however, molecular data has little information content alone, and is only significant when selected most-informative variables are placed in the context of the patient's clinical and pathological measures. Furthermore, classifiers based on support vector machines (SVMs) that predict one-year PFS and three-year OS with high accuracy, show how the addition of carefully selected molecular measures to clinical and pathological knowledge can enable personalized prognosis predictions. Finally, the high-performance of these classifiers are validated on an additional data set. A second study, an analytical approach differentiates between individual and collective tumour invasion, analyses a set of morphological measures. These morphological measurements are collected with a newly developed process using automated imaging analysis for data collection in combination with a Bayesian network analysis to probabilistically connect morphological variables with tumour invasion modes. Between an individual and collective invasion mode, cell-cell contact is the most discriminating morphological feature. Smaller invading groups were typified by smoother cellular surfaces than those invading collectively in larger groups. Interestingly, elongation was evident in all invading cell groups and was not a specific feature of single cell invasion as a surrogate of epithelialmesenchymal transition. In conclusion, the combination of automated imaging analysis and Bayesian network analysis provides an insight into morphological variables associated with transition of cancer cells between invasion modes. We show that only two morphologically distinct modes of invasion exist. The two studies performed in this thesis illustrate the potential of a systems approach for pathology and illustrate the need of quantitative approaches in order to reveal the system behind pathology.
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Kavanagh, Mary-Claire Anne. "Measurement of oxygen levels in murine tumours." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape10/PQDD_0009/NQ41447.pdf.

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Collingridge, David Roy. "Measurement and manipulation of tumour oxygen tension." Thesis, University College London (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.299928.

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Calhoun, Mark A. II. "Measurement and Variation of the Mechanical Environment in Glioblastoma." The Ohio State University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=osu1503252735120506.

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Lawton, Patricia Ann. "The measurement of intrinsic cellular radiosensitivity in human tumours and normal tissues." Thesis, University College London (University of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283750.

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Warmuth, Carsten. "Nichtinvasive Magnetresonanz-Perfusionsmessung des Gehirns mittelsMagnetischer Blutbolusmarkierung(Spin-Labeling)." Doctoral thesis, Humboldt-Universität zu Berlin, Medizinische Fakultät - Universitätsklinikum Charité, 2003. http://dx.doi.org/10.18452/15025.

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Die magnetische Blutbolusmarkierung (Spin-Labeling) ermöglicht die nichtinvasive quantitative Messung des Blutflusses im Gewebe. Beim Spin-Labeling wird arterielles Blut durch Radiofrequenzpulse magnetisch markiert und der Transport der Markierung MR-tomographisch gemessen. Am Modell einer unter physiologischen Bedingungen perfundierten extrakorporalen Schweineniere konnte die Quantifizierbarkeit der Messmethode nachgewiesen werden. In einer Studie an 36 Hirntumorpatienten wurde das Verfahren mit der kontrastmittelbasierten First-Pass-Bolus-Methode zur nicht-quantitativen Perfusionsmessung verglichen. Es zeigte sich eine sehr gute Übereinstimmung zwischen beiden Methoden, der lineare Korrelationskoeffizient des relativen Blutflusses in der Tumorregion lag bei R=0,83. Die mittels Spin-Labeling ermittelten Absolutwerte des Blutflusses spielen bei der Beurteilung des Tumorgrades eine untergeordnete Rolle, da die mittlere Perfusion individuell sehr verschieden ist. Ein zweiter Anwendungsbereich für das Spin-Labeling ist die Darstellung großer Arterien. Spin-Labeling ermöglicht die nichtinvasive dynamische Angiographie (Dynamische Spin-Labeling-Angiographie - DSLA). Analog zur digitalen Subtraktionsangiographie kann damit der Einstromvorgang des Blutes in den Gefäßbaum zeitaufgelöst gemessen werden, jedoch mit wesentlich höherer zeitlicher Auflösung und frei wählbarer Projektionsrichtung. In einer Studie an 18 Patienten mit einseitigen Carotisstenosen wurden die Zeitdifferenzen der Anflutung der zerebralen Gefäße zwischen der betroffenen und der nicht stenosierten Seite bestimmt. Die im Carotis-Siphon gemessenen Zeitdifferenzen korrelieren signifikant mit dem Stenosegrad, steigen aber erst ab einer Lumeneinengung oberhalb von 80 Prozent deutlich an. Im Vergleich zu den etablierten Methoden werden die Möglichkeiten und Grenzen der DSLA dargestellt.
Arterial spin labeling methods allow to determine quantitative tissue blood flow values noninvasively. Arterial blood is labelled by an inversion pulse and the distribution of this intrinsic tracer is measured using magnetic resonance imaging. Experiments using an extra corporal in-vitro porcine kidney in a MR compatible set-up were carried out to determine the accuracy of blood flow values calculated from arterial spin labeling measurements. In a study of 36 brain tumor patients, spin labeling was compared to non-quantitative contrast-enhanced dynamic susceptibility-weighted perfusion imaging. Relative blood flow values determined with both methods were in good agreement, the linear regression coefficient in the tumor region was R=0.83. Due to the variable individual perfusion state, quantitative blood flow values determined using spin labeling play a minor role in the assessment of tumor grade. Application of spin labeling to angiography of major arteries was investigated. Dynamic spin labeling angiography (DSLA) sequences were implemented and tested on a clinical scanner. This technique allows time-resolved depiction of blood flow in large vessels with very high temporal resolution. As opposed to digital subtraction angiography, the method allows arbitrary projection directions. In a study, 18 patients with one-sided carotid stenoses were examined. In these patients the time differences of blood bolus arrival at both hemispheres were determined. Time differences measured in the carotid siphon show a significant correlation with the degree of stenosis. However, a clear increase is not seen until 80% narrowing of a carotid. Possibilities and limitations of the DSLA method are discussed in comparison to established techniques.
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McHugh, Damien Joseph. "The effect of tumour microstructure on diffusion-weighted MRI measurements." Thesis, University of Manchester, 2015. https://www.research.manchester.ac.uk/portal/en/theses/the-effect-of-tumour-microstructure-on-diffusionweighted-mri-measurements(9821717e-df69-4dd0-baf7-51cf27a18aa2).html.

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By sensitising the magnetic resonance signal to the diffusion of water molecules in tissue, diffusion-weighted magnetic resonance imaging provides a means of assessing tumour microstructure non-invasively. Such measurements have the potential to provide important information about tumour development and the response of tumours to treatment, but the way in which different tissue properties affect the diffusion-weighted signal remains unclear. Through simulations, in vivo studies and phantom experiments, this thesis investigates the relationship between the diffusion-weighted signal, the pulse sequence parameters used for acquisition, and microstructural properties of tumours. The use of oscillating gradient pulse sequences on a clinical scanner was investigated initially, with theoretical and practical considerations leading subsequent work to focus on pulsed gradient sequences. The forward problem of predicting the diffusion-weighted signal for given combinations of tissue properties and sequence parameters was addressed numerically through Monte Carlo simulations, focussing on how tumour cell size, intracellular volume fraction and membrane permeability affect the signal. These simulations allowed the sensitivity of the signal to changes in these tissue properties to be investigated, revealing how sensitivity depends on sequence parameters as well as the specific microstructural configuration. By repeating the simulations using the specific sequence parameters used in a clinical and preclinical study, the sensitivity of the implemented protocols was assessed, and linked to the experimental findings. The preclinical study illustrated the importance of the diffusion time in determining the sensitivity to treatment-induced changes in tumours, with larger post-treatment signal changes observed at longer diffusion times. These trends were qualitatively reflected in the sensitivity analysis derived from the simulations. Finally, the inverse problem of estimating microstructural properties from the diffusion-weighted signal was addressed using a physical phantom designed as a simple mimic of tumour tissue. By fitting a biophysical model to the diffusion data, the size and volume fraction of the approximately spherical 'cells' were estimated. The radius was slightly underestimated compared with that determined from independent measurements, the fitted volume fraction was plausible, and parameters were found to be estimated with reasonably good precision.
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Ghara'ati, H. "The use of tomography images in the XRF measurement of platinum in tumours following chemotherapy." Thesis, Swansea University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.637048.

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The technique of X-ray fluorescence of heavy elements is widely used in medical physics and has been used for tracing the platinum-based drugs administered for the treatment of malignant tumours. A method is developed for analyzing an in vivo XRF system and optimizing the system for measuring the absorption of platinum in the target. The nature of the emitted radiation and its interaction with materials are explained. The general principles of the Monte Carlo method are described. A flexible program for an annular source/collimator and back-scattering geometry is developed. Several techniques are employed to improve the statistics and the program calculates the XRF spectrum for several heavy elements simultaneously. The dimensions and shielding materials of the source collimator are investigated in detail. The results support the choice of tungsten with a thin lining of tin or copper. The background spectrum contains a prominent Compton peak, the region above this containing mainly singly-scattered photons and the region below mainly multiply-scattered photons (plus the target element K-line). Very few of these multiply-scattered photons originate in the phantom, and the high background observed experimentally in the low-energy region is therefore attributed to scattering on the surface of the detector collimator. A design is proposed which would reduce this scattering considerably. A matrix of detection sensitivity versus depth and radius of the field is obtained. To calculate the response due to the tumour one can integrate the sensitivity over the volume of the tumour using data obtainable from tomographic images (like CT or MRI). It is also found that the regions of producing the greatest number of K-photons are not directly visible from the detector. A design is proposed which corrects for this deficiency and should therefore greatly improve the detection limit.
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Richter, Johan. "Fluorescence Guided Resection of Brain Tumors : Evaluation of a Hand-held Spectroscopic Probe." Doctoral thesis, Linköpings universitet, Institutionen för medicinsk teknik, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-139793.

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Malignant gliomas grow infiltrative in the brain and can therefore not be completely removed by neurosurgical means. However, for an optimized oncological treatment it has proven useful to resect as much as possible of tumor. The identification of the tumor in the marginal zone is difficult but crucial. Studies have shown that visualization of the specific enhancement of 5-aminolevulinic acid(5-ALA) in the tumor can help to maximize the resection. The Department of Biomedical Engineering, Linköping University, has developed an optical hand-held probe (HHP) to identify tumor tissue with a high sensitivity by means of fluorescence spectroscopy. The technical design and the optical properties of the probe were gradually developed in a standard neurosurgical setting during resection of malignant gliomas. The device could easily be implemented in the operating room, meeting all requirements in terms of sterile handling and without interference of any kind with other equipment. The integration of the device in a navigation system and its use in combination with a blue light surgical microscope were simple. Measurements in 27 operations during resection of malignant gliomas were compared to results from biopsies from the same tumor locations. The equipment was tested as a stand-alone device (n = 180), integrated in a navigation system or in combination with the blue light microscope (n = 190). A ratiocal culated from the measurements enabled objective and comparable values for different tissue types, in correspondence with the findings from the histopathological examinations and in accordance with the navigation system as well as with the surgical microscope.The marginal zone was explored and tumor fluorescence could be identified beyond the fluorescence as seen through the microscope. A higher sensitivity of the HHP was confirmed; the specificity was lower. The combined use of the HHP with a navigation system and with asurgical microscope was beneficial.
Maligna hjärntumörer växer infiltrerande i hjärnan och kan därförinte helt avlägsnas genom kirurgiska operationer. För en optimerad behandling har det emellertid visat sig vara av värde att avlägsna såmycket som möjligt av tumörvävnaden. Identifiering av tumören i gränszonen är mycket svårt, men avgörande. Studier har visat att visualisering av den specifika laddningen av 5-aminolevulinsyra (5-ALA) i tumören kan bidra till att maximera resektionen. Institutionen för Medicinsk Teknik (IMT) på Linköpings universitet,har utvecklat en liten handhållen optisk prob (HHP) för att identifiera tumörvävnad med hög känslighet med hjälp avfluorescens-spektroskopi. Den tekniska konstruktionen och de optiska egenskaperna hos proben utvecklades stegvis genom testning i flera neurokirurgiska operationer för resektion av maligna gliom. Utrustningen uppfyllde alla krav när det gällde steril hantering i operationssalen och kunde användas utan störningar av något slag med annan operationsutrustning. Integreringen i ett navigerings-system och användningen i kombination med ett kirurgiskt mikroskop för fluorescens-styrd kirurgi var oproblematiska. Mätningar under 27 operationer vid resektion av maligna gliom jämfördes med resultat från biopsier från samma tumörtagningsställen. Utrustningen testades såväl som en fristående enhet (n = 180) och som integrerad i ett navigationssystem eller i kombination med mikroskopet (n =190). En särskild kvot beräknad ur mätningarna möjliggjorde objektiva och jämförbara värden för olika vävnader, i överensstämmelse med resultaten från de vävnadspatologiska undersökningarna och i överensstämmelse med navigationssystemet såväl som med det kirurgiska mikroskopet. Tumörernas gränszon undersöktes och tumörfluorescens kunde identifieras bortom fluorescensen som mikroskopet visade. En högre känslighet hos HHP bekräftades; specificiteten var lägre. Den kombinerade användningen av HHP med ett navigationssystem och med ett kirurgiskt mikroskop visade sig vara fördelaktig.
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Leach, Eric. "KNOWLEDGE BASED MEASUREMENT OF ENHANCING BRAIN TISSUE IN ANISOTROPIC MR IMAGERY." Master's thesis, University of Central Florida, 2007. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/3341.

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Medical Image Analysis has emerged as an important field in the computer vision community. In this thesis, two important issues in medical imaging are addressed and a solution for each is derived and synergistically combined as one coherent system. Firstly, a novel approach is proposed for High Resolution Volume (HRV) construction by combining different frequency components at multiple levels, which are separated by using a multi-resolution pyramid structure. Current clinical imaging protocols make use of multiple orthogonal low resolution scans to measure the size of the tumor. The highly anisotropic data result in difficulty and even errors in tumor assessment. In previous approaches, simple interpolation has been used to construct HRVs from multiple low resolution volumes (LRVs), which fail when large inter-plane spacing is present. In our approach, Laplacian pyramids containing band-pass contents are first computed from registered LRVs. The Laplacian images are expanded in their low resolution axes separately and then fused at each level. A Gaussian pyramid is recovered from the fused Laplacian pyramid, where a volume at the bottom level of the Gaussian pyramid is the constructed HRV. The effectiveness of the proposed approach is validated by using simulated images. The method has also been applied to real clinical data and promising experimental results are demonstrated. Secondly, a new knowledge-based framework to automatically quantify the volume of enhancing tissue in brain MR images is proposed. Our approach provides an objective and consistent way to evaluate disease progression and assess the treatment plan. In our approach, enhanced regions are first located by comparing the difference between the aligned set of pre- and post-contrast T1 MR images. Since some normal tissues may also become enhanced by the administration of Gd-DTPA, using the intensity difference alone may not be able to distinguish normal tissue from the tumor. Thus, we propose a new knowledge-based method employing knowledge of anatomical structures from a probabilistic brain atlas and the prior distribution of brain tumor to identify the real enhancing tissue. Our approach has two main advantages. i) The results are invariant to the image contrast change due to the usage of the probabilistic knowledge-based framework. ii) Using the segmented regions instead of independent pixels facilitates an approach that is much less sensitive to small registration errors and image noise. The obtained results are compared to the ground truth for validation and it is shown that the proposed method can achieve accurate and consistent measurements.
M.S.E.E.
School of Electrical Engineering and Computer Science
Engineering and Computer Science
Electrical Engineering MSEE
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Books on the topic "Tumors Measurement"

1

E, Voest Emile, and D'Amore Patricia A, eds. Tumor angiogenesis and microcirculation. New York: Dekker, 2001.

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Jaeger, Katrien De. Relationship between polarographic oxygen measurements, metastatic ability and EF5 binding in murine tumour models. Ottawa: National Library of Canada, 1999.

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National Council on Radiation Protection and Measurements. Comparative carcinogenicity of ionizing radiation and chemicals: Recommendations of the National Council on Radiation Protection and Measurements. Bethesda, MD: The Council, 1989.

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Baak, J. P. A. Manual of quantitative pathology in cancer diagnosis and prognosis. Berlin: Springer-Verlag, 1991.

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Peterson, Hans-Inge. Tumor Blood Circulation: Angiogenesis, Vascular Morphology and Blood Flow of Experimental and Human Tumors. Taylor & Francis Group, 2019.

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Peterson, Hans-Inge. Tumor Blood Circulation: Angiogenesis, Vascular Morphology and Blood Flow of Experimental and Human Tumors. Taylor & Francis Group, 2020.

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Winter, Christian, and Peter Albers. Testicular cancer. Edited by James W. F. Catto. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199659579.003.0090.

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Testicular germ cell tumours (GCTs) represent the most common solid malignancy of young men aged 15–40 years. The disease is rising in incidence. Germ cell tumours are best divided into those with pure seminoma and non-seminoma (NSGCT) histology. While cryptorchidism is clearly established as a risk factor, the pathogenesis of testicular cancer remains unknown. Familial studies and molecular analyses suggest an association to genetic alterations. Most testicular cancer patients present a primary tumour in the testis. Diagnostic examinations include testis palpation and ultrasound, and measurement of serum tumour markers (AFP, ß-HCG, and LDH). Surgical exploration is obligatory for suspected tumours and radical orchidectomy should be performed if a tumour is found. Prognosis and subsequent treatment depends upon the clinical stage and the IGCCCG classification (in case of advanced GCT disease).
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K, Jain Rakesh, and Vaupel Peter, eds. Tumor blood supply and metabolic microenvironment: Characterization and implications for therapy. Stuttgart: G. Fischer, 1991.

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Jill, Eden, Simone Joseph V, and National Cancer Policy Board (U.S.). Committee on Assessing Improvements in Cancer Care in Georgia., eds. Assessing the quality of cancer care: An approach to measurement in Georgia. Washington, D.C: National Academies Press, 2005.

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(Editor), Jill Eden, and Joseph V. Simone (Editor), eds. Assessing the Quality of Cancer Care: An Approach to Measurement in Georgia. National Academies Press, 2005.

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Book chapters on the topic "Tumors Measurement"

1

Mineura, Katsuyoshi, Toshio Sasajima, Masayoshi Kowada, Fumio Shishido, and Kazuo Uemura. "PET Measurement of Tumor Metabolism in Patients with Gliomas." In Biological Aspects of Brain Tumors, 152–57. Tokyo: Springer Japan, 1991. http://dx.doi.org/10.1007/978-4-431-68150-2_17.

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Peskin, Adele P., and Alden A. Dima. "Modeling Clinical Tumors to Create Reference Data for Tumor Volume Measurement." In Advances in Visual Computing, 736–46. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-17274-8_72.

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Aritake, K., H. Segawa, N. Yoshimasu, O. Nakamura, K. Kimura, K. Takakura, and M. Brock. "Cerebral Blood Flow Study in Patients with Intracranial Tumors by CT with Stable Xenon Enhancement." In Cerebral Blood Flow and Metabolism Measurement, 350–55. Berlin, Heidelberg: Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-70054-5_53.

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Moringlane, Jean R. "Measurement of Oxygen Partial Pressure in Brain Tumors under Stereotactic Conditions." In Advances in Experimental Medicine and Biology, 471–77. Boston, MA: Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2468-7_63.

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Müller, W., H. Piazena, A. R. Thomsen, and Peter Vaupel. "Thermography and Thermometry in wIRA-Hyperthermia." In Water-filtered Infrared A (wIRA) Irradiation, 55–67. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-92880-3_4.

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AbstractContact-free temperature determination is based on the measurements of electromagnetic radiation. The corresponding physical laws are related to the properties of black bodies. This background allows for the development of thermometric and thermographic systems for remote temperature measurements. Precise absolute temperature data, required in hyperthermia, do not only depend on the technical quality of the systems (hardware and software) and their calibration, but also depend on accurate determination of the emissivity of human skin. Pyrometers are restricted to temperature measurements within a small area (measurement spot), while thermographic cameras allow measurements across a relatively large region on the target area in real time. The subdivision of the IR image into spatially separated pixels allows access to temperature data of small areas on the skin and thus combines thermometry and thermography. Quality assurance standards of the European Society of Hyperthermic Oncology for water-filtered IR-A-hyperthermia (wIRA-HT) are met, except for the accuracy of the absolute temperature. Since the relation between the temperatures at the skin surface and in deeper tissue layers, considering irradiation and heating time, in wIRA-HT can be assessed, the temperature needed for efficient thermal treatment of superficial tumors within superficial tissue layers can therefore be achieved in a controlled manner.
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Tang, Peng-Peng P. Zhu, Martin P. Schweizer, J. Rock Hadley, Shonn P. Hendee, Richard H. Tippets, and Kenneth M. Bradshaw. "T1 Measurement to Study the Penetration of BNCT Agents Into Canine Tumors Caused by Blood Brain Barrier Damage." In Cancer Neutron Capture Therapy, 541–46. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4757-9567-7_77.

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Pion, Eric, Silke Haerteis, and Thiha Aung. "Application of Laser Speckle Contrast Imaging (LSCI) for the Angiogenesis Measurement of Tumors in the Chorioallantoic Membrane (CAM) Model." In Methods in Molecular Biology, 141–53. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2703-7_11.

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Douis, Hassan, and A. Mark Davies. "Bone and Soft Tissue Tumours." In Measurements in Musculoskeletal Radiology, 823–41. Berlin, Heidelberg: Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-540-68897-6_21.

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Okunieff, Paul, Walter O’Dell, Mei Zhang, Lurong Zhang, and David Maguire. "Tumor Oxygen Measurements and Personalized Medicine." In Advances in Experimental Medicine and Biology, 195–201. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-4989-8_27.

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Terris, D. J., A. I. Minchinton, E. P. Dunphy, and J. M. Brown. "Computerized Histographic Oxygen Tension Measurements of Murine Tumors." In Oxygen Transport to Tissue XIV, 153–59. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3428-0_15.

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Conference papers on the topic "Tumors Measurement"

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Young, William K., Borivoj Vojnovic, and Peter Wardman. "Fiber optic sensor for oxygen measurement in tumors." In BiOS Europe '95, edited by Nathan I. Croitoru, Mitsunobu Miyagi, Guillermo Orellana, Annamaria Verga Scheggi, and Henricus J. C. M. Sterenborg. SPIE, 1995. http://dx.doi.org/10.1117/12.229191.

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Kinouchi, Y., T. Iritani, T. Ushita, T. Morimoto, S. Kimura, Y. Konishi, and Y. Monden. "Impedance measurement of tumors and its application to diagnoses." In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 1988. http://dx.doi.org/10.1109/iembs.1988.95105.

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Maglich, Bogdan C., and Orhan Nalcioglu. "‘ONCOSENSOR’ for Noninvasive High-Specificity Breast Cancer Diagnosis by Carbogen-Enhanced Neutron Femto-Oximetry." In ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13295.

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Based on the first experiment on Differential Femto Oximetry (Paper 13270), we conducted a computer simulated study of the feasibility of conceptual design for our noninvasive malignancy probe, Oncosensor, to diagnose hypoxia of malignancy M = −0.90, measured by pO2 — which correspond to volume averaged hypoxia M′ = −0.09 — in 1cm, 3 cm and 5 cm DIA tumors embedded in the middle of a 10 cm DIA breast. M′ is further masked by background γ’s from the in vivo tissue by factor x = 4.4–7 for subcutaneous and central tumor, respectively, to apparent M″ = M′/X which, in turn, renders hypoxia non-diagnosable for 1 cm tumors; marginally so for 3 cm ones with specificity S = 75%, and fully diagnosable with S = 95% in 5 cm ones. To diagnose 1–3 cm and smaller tumors, we propose to enhance M″ by a factor of ≈ 3 by replacing air breathing with that of Carbogen (O2 95%, CO2 5%). With carbogen breathing, simulations predict hypoxia detection in 1 cm subcutaneous tumor with S = 68%, and in 3 cm ones with S = 95–99.9%. Carbogen renders possible 2 additional diagnostic tests for redundancy. Significant improvements of the above measurement accuracies are projected. Oncosensor will be tested in vivo with R3230 tumors in Fischer rats at UCI’s Center for Functional Onco-Imaging. Oncosensor requires imaging guidance.
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O’Neill, Brian E., Timothy P. Quinn, and King C. P. Li. "A Confined Compression Technique for Hydraulic Conductivity Measurement in Soft Tissues." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176166.

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Multiphasic tissue models have been used extensively to predict the behavior of cartilaginous tissues [1]. Their application to other soft tissues, however, has often been overlooked. Unlike the more commonly used continuum model of the viscoelastic solid [2], multiphasic models allow us to infer the behaviors and properties of tissue subcomponents by observing the behavior of the tissue whole. As a great deal of tissue function and structure is related to the control and transport of fluids and fluid-borne agents, there is clearly a need for this insight in all tissues. For example, there has been a great deal of interest recently in the possibility of modifying the flow properties of solid tumors and other tissues to allow the targeted delivery of large molecular weight drugs, such as chemotherapeutic or genetic agents [3–4]. It is well known that the high interstitial fluid pressures, confused vasculature, and lack of a lymphatic system prevent the effective distribution of directly injected or systemically administered drugs into tumors [3]. Increasing the effective permeability of these tumors can ameliorate these issues and allow for more effective treatment. A handful of studies have found that the biphasic model, along with some basic experimental tools, can reasonably represent the flow properties of tumors [4–5]. In this paper, we describe a technique using a simple confined compression experiment with the biphasic model to measure the hydraulic conductivity of samples of cardiac tissue.
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Sequin, Emily, Karen Bellman, Scott Koch, Joseph West, Shaurya Prakash, and Vish Subramaniam. "Measurement of Electrical Impedance and Eddy Currents in Tissue Phantoms." In ASME 2013 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/imece2013-65112.

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Measurement of the electromagnetic (EM) properties of tissue such as electrical conductivity, permittivity, and eddy current characteristics can be used in clinical medicine for characterizing and distinguishing soft tissue morphology. Such measurements can yield complementary information to what can be obtained using analysis with an optical microscope. An example is the assessment of margins during the surgical resection of occult tumors. In current practice, the surgeon relies on pre-operative imaging modalities, sight and palpation to locate and attempt to fully resect the tumor(s). Frozen section pathological assessment offers the only other resource available to the surgeon for margin analysis, but it is incomplete because only a small fraction of the resected tissue is examined and it is often not feasible to wait for the results of the frozen section analysis before completing the surgery. This paper describes a characterization and imaging method based on variations in electromagnetic tissue properties to assess the surgical margins of resected tissues. This is noteworthy because accurate margin assessment has been shown to significantly improve long term patient outcomes[1].
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Han, Bumsoo, Willard L. Hanson, Karim Bensalah, Altug Tuncel, Joshua Stern, and Jeffrey A. Cadeddu. "Spatiotemporal Temperature Measurement Using Quantum Dot Thermometry During Nanoshell Mediated Thermal Therapy." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192658.

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Due to advances and routine use of various diagnostic technologies, tumors are increasingly detected at very early stages. Thus, there is growing interest in employing minimally invasive surgical techniques for the management of tumors. Many of these procedures are thermal therapies, in which localized thermal lesions, either hyperthermic or cryogenic, are created to destroy malignant tissue in situ. However, the major drawback to the widespread dissemination and acceptance of thermal therapy is the lack of a reliable real-time intraoperative monitoring technique of the thermal lesion.
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Brown III, Edward B., Robert B. Campbell, Yoshikazu Tsuzuki, Dai Fukumura, and Rakesh K. Jain. "Measurement of physiological parameters in tumors in vivo using MPLSM." In BiOS 2001 The International Symposium on Biomedical Optics, edited by Ammasi Periasamy and Peter T. C. So. SPIE, 2001. http://dx.doi.org/10.1117/12.424547.

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Guo, Zhixiong, Siew Kan Wan, David A. August, Stanley M. Dunn, and John L. Semmlow. "Tumor Imaging Through Temporal Log-Slope Difference Mapping of Transient Radiation Signals." In ASME 2004 International Mechanical Engineering Congress and Exposition. ASMEDC, 2004. http://dx.doi.org/10.1115/imece2004-61788.

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A novel optical approach is proposed for cancerous tumor detection using transient radiation signals. In this method, target tissue is illuminated by near-infrared ultrashort laser pulses from various surface source points, and backscattered time-resolved light signals are collected at the same surface points. By analyzing the log-slopes of decaying signals over all points on the source-detection grid, a log-slope distribution on the surface is obtained. After administration of absorption contrast agents, the presence of cancerous tumors increases the decaying steepness of the transient signals. The mapping of log-slope difference between native tissue and absorption-enhanced cancerous tissue indicates the location and projection of tumors on the detection surface. In this paper, we examine this method through the detection of a small tumor in a model tissue phantom via computer simulation. The model has a spherical tumor of 6 mm in diameter embedded at the tissue center. Monte Carlo methods were employed to simulate the light transport and signal measurement. It is shown that the tumor in the tissue model can be accurately projected onto the detection surface by the proposed log-slope difference mapping method. The image processing is very fast and does not require any inverse optimization in image reconstruction.
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Hettich, David, Megan Olson, Andie Jackson, and Naima Kaabouch. "Breast Cancer: Classification of Tumors Using Machine Learning Algorithms." In 2021 IEEE International Conference on Computational Intelligence and Virtual Environments for Measurement Systems and Applications (CIVEMSA). IEEE, 2021. http://dx.doi.org/10.1109/civemsa52099.2021.9493583.

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Choe, Regine, Chao Zhou, Turgut Durduran, Guoqiang Yu, Natasha Shah, Amanda Durkin, Albert Cerussi, Bruce J. Tromberg, and A. G. Yodh. "Neoadjuvant Chemtherapy Monitoring with Diffuse Optical Measurement of Blood Flow in Breast Tumors." In Biomedical Topical Meeting. Washington, D.C.: OSA, 2006. http://dx.doi.org/10.1364/bio.2006.sh27.

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Reports on the topic "Tumors Measurement"

1

Milosevic, Michael F. A Study of Transrectal Tumor Oxygen Measurements in Patients Which Clinically Localized Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, August 2004. http://dx.doi.org/10.21236/ada433026.

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Milosevic, Michael F., Ants Toi, Joan Sweet, Robert Bristow, and David Hedley. A Study of Transrectal Tumor Oxygen Measurements in Patients with Clinically Localized Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, August 2002. http://dx.doi.org/10.21236/ada410273.

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Milosevic, Michael, Ants Toi, Joan Sweet, Robert Bristow, David Hedley, Tony Panzarella, and Richard Hill. A Study of Transrectal Tumor Oxygen Measurements in Patients with Clinically Localized Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, August 2006. http://dx.doi.org/10.21236/ada472885.

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Symmans, W. F. Integration of Pathologic Findings With Clinical-Radiologic Tumor Measurements to Quantify Response to Neoadjuvant Chemotherapy. Fort Belvoir, VA: Defense Technical Information Center, June 2005. http://dx.doi.org/10.21236/ada455291.

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Symmans, William F. Integration of Pathologic Findings With Clinical-Radiologic Tumor Measurements to Quantify Response to Neoadjuvant Chemotherapy. Fort Belvoir, VA: Defense Technical Information Center, June 2004. http://dx.doi.org/10.21236/ada433045.

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Symmans, William F. Integration of Pathologic Findings With Clinical-Radiologic Tumor Measurements to Quantify Response to Neoadjuvant Chemotherapy. Fort Belvoir, VA: Defense Technical Information Center, June 2003. http://dx.doi.org/10.21236/ada420419.

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