Academic literature on the topic 'Tuberculosis Reporting Nepal'

Occurrence of Sporotrichosis is uncommon in Nepal. Here, we describe a case of cutaneous Sporotrichosis of 43 years old adult male working as a farmer from Pokhara-30, Nepal with unusual skin tuberculosis like presentation since 3 years, initiating from the unusual location in right pinna. Histopathological observation was suggestive of cutaneous tuberculosis, lupus vulgaris, cutaneous leishmaniasis due to overlapping findings during biopsy. The case was diagnosed by the pharma­cological intervention observing the effect of drugs i.e., terbinafine. The purpose of reporting this serendipitous case is to enhance timely diagnosis, avoid the diagnostic dilemma for future references.

Introduction: Tuberculosis of the tongue is one of the less common lesions caused by the mycobacterium bacilli whether primary or secondary. Most of the reported cases in the literature are in association with pulmonary lesion or a primary focus elsewhere. Case Report: We report a case of 63 years old male patient from Rajghat, Morang, Nepal with burning sensation over tongue since 30 days. Microscopic examination revealed epithelioid cell granuloma, caseous necrosis and Langhans giant cell with Acid Fast Bacilli on Ziehl Neelsen staining. Conclusion: Lingual Tuberculosis is a diagnostic dilemma because of its rarity. Hence, we are reporting this case. DOI: http://doi.dx.org/10.3126/ijim.v2i1.8006 Int J Infect Microbiol 2013;2(1):26-28

Background and Objectives: Tuberculosis remains one of the major public health problems in Nepal. This study was carried out to assess the Health related Quality of life and Anxiety- Depression level of Tuberculosis patients in Kathmandu.Material and Methods: A cross-sectional study was conducted at Urban Direct Observation Treatment Short Course center using 150 study populations. Questionnaires containing socio-demographic characteristics, Self Reporting Questionnaire, Short Forms Health Survey, Hamilton Anxiety Rating Scale, and Hamilton Depression Rating Scale. SPSS 20, SF-36 Scoring Software were used for data management.Results: Majority of respondents (57.3%) were male, age group of 21-25 years. Majority of respondents suffered from Extra Pulmonary Tuberculosis, gland TB was in higher prevalence (31.3%). Most of the respondents found to poor HRQoL score where only 1.4% female and 1.7% male’s had above average HRQoL. There was no correlation between anxiety, depression, Mental Component Summary and Physical Component Summary score in pulmonary Tuberculosis patients unlike Extra pulmonary Tuberculosis patients, where there was strong correlation between anxiety and depression (r=0.721, p=0.000). There was negative correlation between PCS and MCS (r= -0.232, p= 0.037). There was no association between gender and PCS score on both types of TB patients. At majority of domain of HRQoL male had higher score than female.Conclusion: Co-morbidities of anxiety and depression in tuberculosis patients impact on health-related quality of life.Janaki Medical College Journal of Medical Sciences (2016) Vol. 4 (1): 13-18

Tuberculosis of breast is a rare disease even in endemic areas accounting for 0.1%- 0.5% of all infections. Multiparous young females are commonly affected particularly during pregnancy and lactation. In the present study, we are reporting a case of tuberculosis of breast with ipsilateral axillary involvement in a multiparous young non lactating female. Diagnosis was confirmed after cytological evaluation. Clinical or radiological distinction of mammary tuberculosis from breast carcinoma or abscess is often difficult to achieve. Cytology is an effective method for confirmation of these uncommon disorder an also can reduce unnecessary surgery which should be restricted for complicated cases. Nepal Journal of Medical Sciences | Volume 02 | Number 02 | July-December 2013 | Page 187-189 DOI: http://dx.doi.org/10.3126/njms.v2i2.8974

Background In the last decade, active case finding (ACF) strategies for tuberculosis (TB) have been implemented in many diverse settings, with some showing large increases in case detection and reporting at the sub-national level. There have also been several studies which seek to provide evidence for the benefits of ACF to individuals and communities in the broader context. However, there remains no quantification of the impact of ACF with regards to reducing the burden of transmission. We sought to address this knowledge gap and quantify the potential impact of active case finding on reducing transmission of TB at the national scale and further, to determine the intensification of intervention efforts required to bring the reproduction number (R0) below 1 for TB. Methods We adopt a dynamic transmission model that incorporates heterogeneity in risk to TB to assess the impact of an ACF programme (IMPACT TB) on reducing TB incidence in Vietnam and Nepal. We fit the models to country-level incidence data using a Bayesian Markov Chain Monte Carlo approach. We assess the impact of ACF using a parameter in our model, which we term the treatment success rate. Using programmatic data, we estimate how much this parameter has increased as a result of IMPACT TB in the implementation districts of Vietnam and Nepal and quantify additional efforts needed to eliminate transmission of TB in these countries by 2035. Results Extending the IMPACT TB programme to national coverage would lead to moderate decreases in TB incidence and would not be enough to interrupt transmission by 2035. Decreasing transmission sufficiently to bring the reproduction number (R0) below 1, would require a further intensification of current efforts, even at the sub-national level. Conclusions Active case finding programmes are effective in reducing TB in the short term. However, interruption of transmission in high-burden countries, like Vietnam and Nepal, will require comprehensive incremental efforts. Complementary measures to reduce progression from infection to disease, and reactivation of latent infection, are needed to meet the WHO End TB incidence targets.

Abstract Background Brief behavioural support can effectively help tuberculosis (TB) patients quit smoking and improve their outcomes. In collaboration with TB programmes in Bangladesh, Nepal and Pakistan, we evaluated the implementation and scale-up of cessation support using four strategies: (1) brief tobacco cessation intervention, (2) integration of tobacco cessation within routine training, (3) inclusion of tobacco indicators in routine records and (4) embedding research within TB programmes. Methods We used mixed methods of observation, interviews, questionnaires and routine data. We aimed to understand the extent and facilitators of vertical scale-up (institutionalization) within 59 health facility learning sites in Pakistan, 18 in Nepal and 15 in Bangladesh, and horizontal scale-up (increased coverage beyond learning sites). We observed training and surveyed all 169 TB health workers who were trained, in order to measure changes in their confidence in delivering cessation support. Routine TB data from the learning sites were analysed to assess intervention delivery and use of TB forms revised to report smoking status and cessation support provided. A purposive sample of TB health workers, managers and policy-makers were interviewed (Bangladesh n = 12; Nepal n = 13; Pakistan n = 19). Costs of scale-up were estimated using activity-based cost analysis. Results Routine data indicated that health workers in learning sites asked all TB patients about tobacco use and offered them cessation support. Qualitative data showed use of intervention materials, often with adaptation and partial implementation in busy clinics. Short (1–2 hours) training integrated within existing programmes increased mean confidence in delivering cessation support by 17% (95% CI: 14–20%). A focus on health system changes (reporting, training, supervision) facilitated vertical scale-up. Dissemination of materials beyond learning sites and changes to national reporting forms and training indicated a degree of horizontal scale-up. Embedding research within TB health systems was crucial for horizontal scale-up and required the dynamic use of tactics including alliance-building, engagement in the wider policy process, use of insider researchers and a deep understanding of health system actors and processes. Conclusions System-level changes within TB programmes may facilitate routine delivery of cessation support to TB patients. These strategies are inexpensive, and with concerted efforts from TB programmes and donors, tobacco cessation can be institutionalized at scale.