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Al-Khatib, Zaid, and n/a. "Total Skin Electron Therapy Using Beam Modifiers." RMIT University. Applied Science, 2006. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20080627.123744.
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The short range of low energy electrons from 2 to 9 MeV has made them useful for the treatment of superficial lesions covering large areas of the body, such as mycosis fungoides and other cutaneous lymphomas. At these electron energies, the beam penetration falls off rapidly beyond a shallow depth. Thus superficial lesions can be treated up to few millimeters without exceeding the tolerance of the bone marrow. The purpose of this project was to study the effect of the beam modifiers on the characteristics of the Varian 2100C 6 MeV beam using high dose rate total skin electron mode (HDTSe). The technique developed in the study was a modified Stanford Technique. In this technique, the patient is treated with dual six fields using + 17.5o angle above and below the horizontal line at 350 cm SSD. The patient is rotated every 60o intervals so that the whole skin surface is covered with the beam. The scattering filter used in the study was two strips of non-exposed developed radiographic films. The filter was mounted on the HDTSe applicator. The dose uniformity within a rectangle of 160 cm x 60 cm was found to be + 3% along the vertical direction and + 4% along the horizontal direction which meets the beam requirements recommended by the AAPM report (23) [61]. The use of the scattering filter has improved the dose uniformity, but it increased the x-ray contamination beyond the 30 mm depth to about 1.5% which makes the technique
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Fonseca, Gabriel Paiva. "Projeto e construção de placas espalhadoras e degradadoras de energia para uso em radioterapia com feixes de elétrons para doenças de pele." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/85/85133/tde-10082011-095658/.
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Há diversas enfermidades radiossensíveis epidermotrópicas, como a micose fungóide e a síndrome de Sézary, neoplasias cutâneas originadas de linfócitos do tipo T, que apresentam grande possibilidade de erradicação quando tratadas com feixes de elétrons com energia entre 4 e 10 MeV, conforme apontam diversos estudos. No entanto, esta técnica de tratamento apresenta inúmeras dificuldades práticas, pois a doença dissemina-se por todo o corpo do paciente tornando necessário um grande campo de radiação e deposição de energia limitada à profundidade da pele. A fim de obter uma distribuição de dose uniforme, muitas técnicas já foram desenvolvidas. Com base em estudos anteriores e guiados pelo protocolo n. 23 da American Association of Physicists in Medicine (AAPM), o presente trabalho desenvolveu placas espalhadoras e degradadoras de energia e realizou toda a dosimetria (computacional e experimental), a fim de fornecer subsídios para a implementação da técnica de tratamento Total Skin Electron Therapy (TSET) no Serviço de Radioterapia do Hospital das Clínicas de São Paulo. O programa MCNP4C baseado no método de Monte Carlo foi utilizado para reconstruir o espectro energético do acelerador Varian Clinac 2100C, por meio de medidas experimentais de percentual de dose em profundidade (PDP) e perfis radiais de dose. Com estes dados, foi possível efetuar simulações computacionais para a seleção de materiais, mediante análise da distribuição radial e axial de dose, produção de raios-X e a atenuação do feixe, além da simulação de placas espalhadoras e degradadoras de energia, a serem posicionadas na saída do acelerador. Os resultados das simulações foram validados por meio de medidas experimentais a fim de obter um grande campo de radiação com 200 cm x 80 cm que atendesse as especificações do protocolo da AAPM.There are many radiosensitive epidermotropics diseases such as mycosis fungoids and the syndrome of Sézary, coetaneous neoplasics originated from type T lymphocytes. Several studies indicate the eradication of the disease when treated with linear accelerators emitting electron beams with energies between 4 to 10 MeV. However, this treatment technique presents innumerable technical challenges since the disease in general reaches all patient´s body, becoming necessary not only a very large field size radiation beam, but also deliver superficial doses limited to the skin depth. To reach the uniformity in the dose distribution, many techniques had already been developed. Based on these previous studies and guided by the report n. 23 of the American Association of Physicists in Medi-cine (AAPM), the present study developed an energy scattering and degrading plates and made dosimetry (computational and experimental), supplying subsidies for a future installation of Total Skin Electron Therapy (TSET) at the Serviço de Radioterapia do Hospital das Clínicas de São Paulo. As part of the plates design, first of all, the energy spectrum of the 6 MeV electron beam of the VARIAN 2100C accelerator was reconstructed through Monte Carlo simulations using the MCNP4C code and based on experimental data. Once the spectrum is built, several materials were analyzed for the plates design based on radial and axial dose distribution, production of rays-x and dose attenuation. The simulation results were validated by experimental measurements in order to obtain a large field of radiation with 200 cm x 80 cm that meets the specifications of the AAPM protocol.
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Dubois, Sylvie. "Propriétés électroniques des composés à ondes de densité de charge KMo6017, NbSe3 et (TSeT)2CI : Etude par magnétotransport en champ magnétique intense." Toulouse, INSA, 1993. http://www.theses.fr/1993ISAT0028.
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Des mesures de magnetoresistance a fort champ magnetique ont ete realisees sur les trois composes de basse dimensionnalite suivants: le bronze violet quasi bidimensionnel kmo#6o#1#7, le trichalcogenure nbse#3 et le conducteur organique (tset)#2cl. Dans l'etat onde de densite de charge basse temperature, ces trois composes presentent des oscillations quantiques de shubnikov-de haas. Pour chacun d'eux, l'oscillation n=0#+ a ete observee et la masse cyclotron ainsi que l'aire des poches de porteurs au niveau de fermi ont pu etre determinees. Une analyse detaillee de la magnetoresistance de kmo#6o#1#7 nous a permis de confirmer le caractere quasi bidimensionnel de l'etat onde de densite de charge et l'existence d'un changement de regime vers 26 k. Nous avons montre que l'ensemble des resultats obtenus sur nbse#3 s'interprete a l'aide du seul modele de l'effet shubnikov-de haas et que la contribution d'une eventuelle rupture magnetique est exclue. Une etude preliminaire de (tset)#2cl confirme le caractere bidimensionnel isotrope des poches de porteurs dans l'etat onde de densite de charge et met en evidence l'importance des effets de trempe sur la structure electronique
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Le, Pevelen Delphine. "Analyse structurale des matériaux soumis simultanément à haute pression et basse température : conception et réalisation de l'appareillage de diffraction des rayons X, application au diagramme de phases de deux conducteurs organiques : (TMTSF)₂ClO₄ et (TSeT)₂Cl." Bordeaux 1, 1999. http://www.theses.fr/1999BOR10566.
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Ce travail de thèse présente la conception et la réalisation, pour la première fois au plan international, d'un ensemble de diffraction X (diffractomètre à incidence normale et chambre Weissenberg verticale) permettant le couplage des contraintes pression et température, ce qui rend désormais possible l'accès d'un point de vue structural à n'importe quel point d'un diagramme de phases P-T. Ce nouvel équipement a été utilisé avec succès pour étudier le comportement structural de deux conducteurs organiques : (TMTSF)₂ClO₄ et (TSeT)₂Cl. Pour chacun d'entre eux, est décrite de manière détaillée l'évolution des caractéristiques structurales sous contraintes avec en particulier la détermination de leur structure cristalline à (5 kbar, 7 k). Ces résultats cristallographiques ont permis de calculer les structures de bandes et surfaces de Fermi, d'établir des corrélations avec les propriétés physiques en expliquant notamment les transitions décelées précédemmentThe work presented in this thesis deals with the design and the achievement, for the first time at the international level, of an X-Ray diffraction instrumentation (normal beam diffractometer and vertical Weissenberg camera) allowing the coupling of the pressure and temperature constraints, which makes possible the access, from a structural point of view, to any point of a P-T phase diagram. This new apparatus has been successfully used to study the structural behaviour of two organic conductors: (TMTSF)₂ClO₄ and (TSeT)₂Cl. For each of them, the pressure and temperature dependence of the structural parameters has been described in detail, with in particular the determination of the crystal structure at (5 kbar, 7 K). Owing to these crystallographic results, the band structures and the Fermi surfaces have been calculated and some correlations have been established with the physical properties, leading to an explanation of the transitions previously detected
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Leopold, Henrik, Jan Mendling, and Artem Polyvyanyy. "Supporting Process Model Validation through Natural Language Generation." Institute of Electrical and Electronics Engineers (IEEE), 2014. http://dx.doi.org/10.1109/TSE.2014.2327044.
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The design and development of process-aware information systems is often supported by specifying requirements
as business process models. Although this approach is generally accepted as an effective strategy, it remains a fundamental
challenge to adequately validate these models given the diverging skill set of domain experts and system analysts. As domain
experts often do not feel confident in judging the correctness and completeness of process models that system analysts create, the
validation often has to regress to a discourse using natural language. In order to support such a discourse appropriately, so-called
verbalization techniques have been defined for different types of conceptual models. However, there is currently no sophisticated
technique available that is capable of generating natural-looking text from process models. In this paper, we address this research
gap and propose a technique for generating natural language texts from business process models. A comparison with manually
created process descriptions demonstrates that the generated texts are superior in terms of completeness, structure, and linguistic
complexity. An evaluation with users further demonstrates that the texts are very understandable and effectively allow the reader
to infer the process model semantics. Hence, the generated texts represent a useful input for process model validation.
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Robert, Alain. "Le Contrôle de l'ovulation et de la parturition chez la Mouche Tsé-Tsé, Glossina fuscipes (Diptère)." Grenoble 2 : ANRT, 1986. http://catalogue.bnf.fr/ark:/12148/cb376007965.
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Rafuse, Lee. "Sleeping with the enemy : tsete-trypanosome interactions." Thesis, University of Liverpool, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.510952.
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KIM, EUNHEE. "L'idee de nature chez jean-jacques rousseau et dans la philosophie taoiste de lao-tseu et de tchouang-tseu." Paris 7, 1996. http://www.theses.fr/1996PA070130.
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Dans la pensee de rousseau comme dans celle des maitres taoistes lao-tseu et de tchouang-tseu, la problematique de la nature prend une dimension considerable, en s'associant aux themes de la culture, de la politique et de l'alienation. L'idee de nature sert de critere dans le jugement des valeurs fondamentales, humaines et universelles. En s'interrogeant sur l'essence de l'homme, rousseau et les philosophes taoistes recherchent le recouvrement de la plenitude de la nature humaineIn rousseau's thought as in the taoist philosophy of lao-tzu and zhuang-tzu, the theme of nature takes a considerable dimension : it embraces divers subjects like culture, politic and alienation. The idea of nature serves as measure in the judgement of human, fondamental and universal values. To question on the human essence, rousseau and the taoist philosophers seek for recovering the plenitude of human nature
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Cho, Myung-Ai. "L'Homme et Dieu chez Pascal et Lao-Tseu." Lille 3 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb376039446.
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Cho, Myung-Ai. "L'homme et dieu chez pascal et lao-tseu." Paris 4, 1987. http://www.theses.fr/1987PA040086.
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Notre travail a pour objet de comparer au travers de leurs oeuvres deux perspectives de penseurs qui ont,chacun a sa facon, profondement marque la vie spirituelle en occident et en extreme-orient. Il vise a degager de la lecture de leurs problematiques, en soulignant les convergences aussi bien que les differences, les lignes de force qui unissent deux humanismes : l'humanisme de type chretien et celui de type taoiste. A partir d'un point commun, qui est le sentiment profond d'appartenance a l'etre divin, et se traduit par une meme aspiration a s'unir avec lui, pascal comme lao-tseu nous fraient une route qui mene a une philosphie du milieu, et debouche finalement sur une quete du bonheur ou du salut. Le sens du divin chez ces deux penseurs est analyse dans la seconde partie ; quant a la troisieme, elle est consacree au sens de la destinee humaine qui revele leur preoccupation constante des problemes de la pensee, de la volonte, du mal et du langage. Notre reflexion nous permet ainsi de cerner, a travers les textes etudies, deux types d'humanisme que distingue, en leur essence, une saisie tres differente de la temporalite. Tout en les confrontant, nous avons essaye d'eviter les rapprochements simplistes ou forces, en tracant des lignes de demarcation rigoureuses entre deux attitudes, deux perspectives, deux traditions enfin.
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Schönherr, Jeremias. "Einfluss von Antipsychotika auf die Zytokinproduktion in-vitro." Doctoral thesis, Universitätsbibliothek Leipzig, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-203760.
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Diese Arbeit beschreibt Ergebnisse einer in-vitro Untersuchung der Antipsychotika
Chlorpromazin, Haloperidol, Clozapin, N-Desmethylclozapin und Quetiapin bezüglich ihrer
Wirkung auf die Zytokinproduktion. Dafür wurde Vollblut von gesunden Probandinnen invitro
mit dem Immunmodulator Toxic-Shock-Syndrome-Toxin-1 (TSST-1) stimuliert. Dabei
wurden die Konzentrationen der Zytokine Interleukin (IL)-1ß, IL-2, IL-4, IL-6, IL-17 und
Tumornekrosefaktor-α (TNF-α) im unstimulierten Blut und im stimulierten Blut, jeweils mit
und ohne Zusatz der Antipsychotika gemessen.
Es zeigte sich, dass TSST-1 eine signifikante Stimulation der Produktion aller getesteten
Zytokine bewirkte und dass es über diese Stimulation mit TSST-1 hinaus zu einer Erhöhung
von IL-17 unter allen getesteten Antipsychotika kam.
Aufgrund dieser Ergebnisse ist es denkbar, dass Antipsychotika, in Ergänzung zu ihrer
Wirkung an Dopaminrezeptoren, auch über diese immunologische Eigenschaft Wirkungen
und Nebenwirkungen entfalten können. Weiterhin könnte die IL-17-Produktion ein
Biomarker in der Behandlung mit Antipsychotika sein, der wiederum zur individuellen
Vorhersage von Wirkungen und Nebenwirkungen beitragen könnte.
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Diarra, Alhousseine. "Suivi de l'évapotranspiration des cultures irriguées du Sud de la Méditerranée par télédétection multi-capteurs et modélisation globale." Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066488/document.
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Avec la pression croissante sur les ressources en eau accentuée par la menace des changementsglobaux, l'agriculture irriguée, surtout dans les régions semi-arides, se trouve confrontée à denouvelles exigences. Une gestion optimale des ressources en eau est indispensable dans les périmètresirrigués afin d'éviter à la fois l'irrigation excessive et le stress hydrique dommageable aux cultures.Dans ce contexte, proposer un outil simple, parcimonieux et robuste, facile à mettre en placepermettant de suivre le besoin réel en eau des cultures, à différentes échelles spatio-temporelles,permettrait d’apporter un indicateur tangible quant à l’efficience de l’irrigation dans les périmètresirrigués. Ce travail de thèse a pour objectif d’évaluer et d’adapter plusieurs outils de suivi del’évapotranspiration des cultures irriguées de l’échelle parcellaire à l’échelle régionale par l’utilisationde la télédétection multi-capteurs et multi-résolution. Notre zone d’étude est le bassin versant duTensift au Maroc, objet d’étude du LMI TREMA (Jarlan et al., 2015) et support de l’observatoireTensift. Nous avons identifié 3 outils : un modèle de bilan d’énergie de surface (TSEB ; Norman et al.,1995) piloté par une observation de température radiométrique qui renseigne indirectement sur l’étathydrique de surface ; l’approche à coefficient cultural double de la FAO-56 (Allen et al., 1998) quiprédit l’état hydrique de surface par la résolution d’un bilan hydrique mais nécessite en contre-partiede connaître précisément les apports d’eau, grandeur très incertaine sur les périmètres irrigués àl’échelle parcellaire ; la modélisation globale qui, par opposition aux deux autres, est une approcheautonome ne nécessitant aucun forçage externe. Dans un premier temps, la confrontation dessimulations du modèle TSEB à un ensemble de mesures expérimentales recueillies à l’échelleparcellaire durant 2 saisons agricoles ainsi qu’à l’approche FAO-56 préalablement calibrée sur lesprincipales cultures de notre région d’étude sur la base de travaux antérieurs a permis de montrer que :- le modèle TSEB est très robuste et offre des performances acceptables pour la prédiction del’évapotranspiration (RMSE < 1mm/jour sur 4 sites lors de deux saisons agricoles) ; - les bonnescapacités de cet outil pour la détection de stress hydrique ; - une bonne aptitude également àpartitionner l’évapotranspiration entre évaporation du sol et transpiration de la plante. Dans un 2èmetemps, nous avons évalué les capacités prédictives d’un modèle global que nous avons développé surla base d’une série temporelle d’évapotranspiration observée sur le terrain. La modélisation globale estbasée sur la théorie des systèmes dynamique non-linéaire. Si elle ne possède pas les capacitésexplicatives des modèles mécanistes évoqués ci-dessus, peut être une bonne alternative pour laprévision de l’évapotranspiration. L’analyse de l’horizon de prévisibilité du modèle global que nousavons obtenu montre un intérêt limité pour les agriculteurs ou les gestionnaires puisque cet horizonn’excède pas 3h. Néanmoins, cette approche, très originale dans ce contexte, reste particulièrementséduisante et ouvre plusieurs perspectives. Enfin, nous avons développé un prototype « tout satellite »,basé sur le modèle TSEB et qui utilise uniquement les produits gratuits MODIS et les ré-analysesERA-Interim, pour le suivi spatialisée et à long terme de la consommation en eau des cultures dans lebassin versant du Tensift. Après une évaluation des forçages ERA-Interim, nous avons évalué laperformance du prototype par (1) confrontation des prédictions des composantes du bilan d’énergieaux données expérimentales de l’observation Tensift et (2) confrontation de la consommationmensuelle prédite au niveau des principaux périmètres irrigués de la région aux apports d’eaumensuels fournis par l’office régional qui gère ces périmètresWith the increasing pressure on water resources accentuated by the climate change threat, irrigated agriculture, especially in semi-arid zone, faced more challenges. Optimal management of water resources is essential in irrigated areas in order to avoid both excessive irrigation and water stress that is harmful to the growth of crops. In this context, proposing a simple, parsimonious and robust, easyto- use tool for monitoring the crop water requirement at different spatial and temporal scales would provide a tangible indicator of irrigation efficiency over irrigated perimeters. This thesis aims to evaluate and adapt several tools for monitoring the evapotranspiration of irrigated crops from the plot scale to the regional scale through the use of multi-sensor and multi-resolution remote sensing observations. Our study area is the Tensift watershed in Morocco, studied by LMI TREMA (Jarlan et al., 2015) and supported by the Tensift observatory. We identified 3 tools: a surface energy balance model (TSEB; Norman et al., 1995) driven by a radiometric temperature observation that provides indirect information on surface water status; the FAO-56 dual crop coefficient approach predicts the hydric status by computing the water balance but requires the know precisely the water input, very difficult to obtain on the plot scale of irrigated perimeters ; global modeling which, as opposed to the first two, is an autonomous approach requiring no external forcing. Firstly, the comparison of the TSEB model simulations with a set of experimental measurements collected on a plot scale during 2 consecutive agricultural seasons and with the results of the calibrated FAO-56 dual crop coefficient approach has shown that : - the TSEB model is very robust and offers acceptable performance for the prediction of evapotranspiration (RMSE <1mm / day during the two agricultural seasons); - a good capabilities of TSEB model for detection water stress; - a good ability also to partition the evapotranspiration between evaporation of the soil and transpiration of the plant. In the second step, we evaluated the predictive capacities of a global model that we developed on the basis of a time series of evapotranspiration observed in the field. Global modeling is based on the theory of the nonlinear dynamic systems theory. If it does not have the explanatory capabilities of the mechanistic models mentioned above, it may be a good alternative for predicting evapotranspiration. The analysis of the horizon of predictability of the global model that we obtained shows a limited interest for the farmers or the managers since this horizon does not exceed 3h. Nevertheless, this approach, very original in this context, remains particularly attractive and opens perspectives. Finally, we have developed a prototype, based on the TSEB model and using only MODIS free products and ERAInterim reanalyses, for monitoring evapotranspiration at Tensift watershed scale and over long periods. After an evaluation of the ERA-Interim products, we evaluated the prototype performance by (1) comparing the predictions of the energy balance components to the experimental data from Tensift observatory and (2) comparing the predicted monthly consumption at the main irrigated perimeters of the region with monthly water supplies provided by the regional office which manages these perimeters. Thus, there is a strong overestimation (almost a factor of 2) of the water consumed compared to the inflow of water, which could be related to the high number of boreholes in the region. This work and the tools developed opens perspectives for piloting and managing agricultural water in semi-arid regions
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Wightman, Lionel. "Linear epitope tagging of the prion protein." Thesis, University of Reading, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.282977.
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Anderson, John A. "Designing and modeling a torque and speed control transmission (TSCT)." Morgantown, W. Va. : [West Virginia University Libraries], 1999. http://etd.wvu.edu/templates/showETD.cfm?recnum=1194.
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Thesis (M.S.)--West Virginia University, 1999.Title from document title page. Document formatted into pages; contains viii, 69 p. : ill. Includes abstract. Includes bibliographical references (p. 68-69).
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Seidel, Anna K. "La divinisation de Lao Tseu dans le taoïsme des Han /." Paris : École française d'Extrême-Orient, 1992. http://catalogue.bnf.fr/ark:/12148/cb35530191z.
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Thèse 3e cycle--Études extrêmes-orientales--Paris, 1968.Thèse soutenue sous le titre : "Évolution et rôle de la divinité suprême aux origines du taoïsme religieux" Contient le texte et une trad. du "Lao tseu ming" de Pien Chao et du "Lao tseu pien houa king" Bibliogr. p. 137-140. Index.
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Love, Charmaine. "PrP catabolites as determinants of TSE susceptibility." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5709.
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Transmissible spongiform encephalopathies (TSEs) are a group of fatal neurodegenerative diseases that are characterised by long incubation periods, protein aggregation and vacuolation. During TSE pathogenesis the normal, cellular prion protein, (PrPC), which is encoded by the gene PRNP, misfolds and accumulates as abnormal disease associated prion protein, (PrPSc) within the central nervous system. Variants of the Prion protein gene are associated with susceptibility to TSE disease. For example sheep scrapie disease is modulated by several PRNP alleles, with certain alleles carried by susceptible animals being different from those carried by resistant animals. The mechanisms linking PRNP genetics and disease is poorly understood but may involve protein sequence, PrPC expression levels, and possibly differences in protein processing. Post-translational modification of PrPC leads to specific cleavage (alpha cleavage) between amino acids 115/116 of ovine PrP, producing two fragments C1 and N1. Cleavage of PrP may occur as a protective mechanism, as a response to changes in the cellular environment or as a feature of an as yet unknown biological function. In the context of TSEs, alpha cleavage may inadvertently provide a protective role by reducing available PrPC protein for conversion into PrPSc, assuming that the C1 fragment would be an inefficient substrate for conversion, the opposite theory was also proposed. The former hypothesis became the focus of this present study, with the idea that total full-length PrPC, total C1 or the ratio between full-length PrPC and C1 may be linked to differences in scrapie susceptibility. To investigate these aims the C1 fragment was measured as a percentage of total PrPC in different PRNP genotypes with varying degrees of susceptibility to scrapie and in different brain regions. This study found that PrPC alpha cleavage increased during development from the new born lamb to the adult sheep, which may have consequences for the susceptibility differences related to age. There are also variations in the amount of alpha cleavage between brain regions such as cortex and medulla that may influence scrapie strain targeting. Overall the amount of the C1 fragment in the different brain areas varied as much as 10x (range 5% to 60%). There was a significant difference in the ratio of C1 to the other PrPC forms between two PRNP genotype groups carrying the VRQ and ARQ allele but there was no correlation between C1 level and scrapie susceptibility or scrapie incubation period in our scrapie models. Alpha cleavage of PrPC also occurs in various transgenic mouse models expressing different ruminant PrP sequences. In PrPC over-expressing transgenic mouse models a higher ratio of C1 was observed, this may suggest a link between PrPC expression levels and alpha cleavage. Transgenic mice are therefore important models to further investigate the link between PrPC biology and scrapie disease phenotype. In conclusion, this thesis has shown for the first time that certain ovine PRNP alleles can influence alpha cleavage of the PrPC protein; however it appears not to be a significant indicator of TSE disease susceptibility in sheep.
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廖永昌 and Wing-cheong Dicky Liu. "Urban Artscape: restructuring of cultural complex, TST." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B31984733.
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Liu, Wing-cheong Dicky. "Urban Artscape : restructuring of cultural complex, TST /." Hong Kong : University of Hong Kong, 1999. http://sunzi.lib.hku.hk/hkuto/record.jsp?
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Bartsch, Stefanie. "Auswirkung von Stimmungsstabilisierern und Antiepileptika auf die Zytokinproduktion in-vitro." Doctoral thesis, Universitätsbibliothek Leipzig, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-156211.
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Die Bedeutung des Immunsystems in der Pathophysiologie von bipolaren Erkrankungen und Epilepsie ist ein aktueller Gegenstand der neuropsychoimmunologischen Forschung. Eine erhöhte Produktion von Zytokinen aufgrund von oxidativem Stress wurde dabei wiederholt als für die Pathophysiologie von Epilepsie und Bipolarer Störung relevant angesehen. In Hinblick auf Veränderungen der Zytokine Interleukin (IL)-1ß, IL-2, IL-4, IL-6 und Tumornekrosefaktor-alpha (TNF-α) wurden z. T. überlappende Ergebnisse bei beiden Erkrankungen beschrieben. Inwiefern diese Zytokine durch Stimmungsstabilisierer und Antiepileptika beeinflusst werden, wurde bisher jedoch nicht systematisch untersucht.
In dieser Studie wurden systematisch in-vitro die Konzentrationen von IL-1ß, IL-2, IL-4, IL-6, IL-17, IL-22 und TNF-α im stimulierten Blut 14 gesunder Frauen mittels Vollblutverfahren (whole blood assay) nach Zugabe von Stimmungsstabilisierern bzw. Antiepileptika gemessen. Es wurden dabei die Stimmungsstabilisierer bzw. Antiepileptika Primidon, Carbamazepin, Levetiracetam, Lamotrigin, Valproat, Oxcarbazepin, Topiramat, Phenobarbital und Lithium untersucht.
Die Ergebnisse lassen darauf schließen, dass der Mechanismus von erwünschter und unerwünschter anderer Wirkung von Stimmungsstabilisierern und Antiepileptika mit der Regulation von IL-1ß, IL-2, IL-22 und TNF-α in Zusammenhang stehen könnte.
Getrennt nach den im Vollblutverfahren verwendeten Stimulanzien – Toxic-Shock-Syndrome-Toxin-1 (TSST-1) vs. monoklonaler Antikörper gegen das CD3-Oberflächenantigen (OKT3) in Kombination mit dem 5C3-Antikörper gegen CD40 (OKT3/CD40) – wurden die Ergebnisse in zwei unterschiedlichen Publikationen berichtet, die dieser Promotion zugrunde liegen.
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Luca, Mihai Bogdan Burel Gilles. "Apports du chaos et des estimateurs d'états pour la transmission sécurisée de l'information." [s.l.] : [s.n.], 2006. http://www.univ-brest.fr/lest/tst/publications/pdf/TheseMihaiBogdanLuca.pdf.
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Thèse doctorat : Sciences et technologies de l'information et de la communication. Spécialité communications numériques : Brest : 2006.Thèse soutenue en co-tutelle. Bibliogr. p.165-177. Index.
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Taheri, Mobarakeh Mohammed. "The histology and cytology of rodent skin reactions to tse tse and sandfly and to sandfly infected with Leishmania." Thesis, University of Salford, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.304674.
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Schönherr, Jeremias. "Einfluss von Antipsychotika auf die Zytokinproduktion in-vitro." Doctoral thesis, Universitätsbibliothek Leipzig, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-151783.
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Diese Arbeit beschreibt Ergebnisse einer in-vitro Untersuchung der Antipsychotika
Chlorpromazin, Haloperidol, Clozapin, N-Desmethylclozapin und Quetiapin bezüglich ihrer
Wirkung auf die Zytokinproduktion. Dafür wurde Vollblut von gesunden Probandinnen invitro
mit dem Immunmodulator Toxic-Shock-Syndrome-Toxin-1 (TSST-1) stimuliert. Dabei
wurden die Konzentrationen der Zytokine Interleukin (IL)-1ß, IL-2, IL-4, IL-6, IL-17 und
Tumornekrosefaktor-α (TNF-α) im unstimulierten Blut und im stimulierten Blut, jeweils mit
und ohne Zusatz der Antipsychotika gemessen.
Es zeigte sich, dass TSST-1 eine signifikante Stimulation der Produktion aller getesteten
Zytokine bewirkte und dass es über diese Stimulation mit TSST-1 hinaus zu einer Erhöhung
von IL-17 unter allen getesteten Antipsychotika kam.
Aufgrund dieser Ergebnisse ist es denkbar, dass Antipsychotika, in Ergänzung zu ihrer
Wirkung an Dopaminrezeptoren, auch über diese immunologische Eigenschaft Wirkungen
und Nebenwirkungen entfalten können. Weiterhin könnte die IL-17-Produktion ein
Biomarker in der Behandlung mit Antipsychotika sein, der wiederum zur individuellen
Vorhersage von Wirkungen und Nebenwirkungen beitragen könnte.
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Cheung, Pui-ching Isis, and 張佩貞. "The study of Tse Tsan Tai (1872-1938)." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1997. http://hub.hku.hk/bib/B31951272.
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梁學敏 and Hok-man Josephine Leung. "[Art] on transit: transportation interchange at Middle Road, TST." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2002. http://hub.hku.hk/bib/B31986596.
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Ng, Victor, and 伍達文. "Art ropolis: redefining the museum of (new) art, TST." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2002. http://hub.hku.hk/bib/B31986717.
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Leung, Hok-man Josephine. "[Art] on transit : transportation interchange at Middle Road, TST /." Hong Kong : University of Hong Kong, 2002. http://sunzi.lib.hku.hk/hkuto/record.jsp?B25948489.
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Ng, Victor. "Art ropolis : redefining the museum of (new) art, TST /." Hong Kong : University of Hong Kong, 2002. http://sunzi.lib.hku.hk/hkuto/record.jsp?B25946080.
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Martin, Joanne. "Proteins as markers of TSE infection in sheep blood." Thesis, University of Southampton, 2008. https://eprints.soton.ac.uk/66257/.
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Transmissible spongiform encephalopathies (TSEs) are a group of fatal infectious neurodegenerative diseases affecting both humans and agricultural animals. TSE transmission via blood transfusion has been demonstrated experimentally in rodent, primate and sheep models. Additionally, in humans, four variant Creutzfeld-Jakob disease (vCJD) cases have been reported which probably resulted from infected blood transfusions. Although TSEs can be transmitted via blood transfusion, little is known about which blood cells are involved in the replication of the TSE agent and how infectivity is spread throughout the body prior to neuroinvasion. There are no currently validated diagnostic tests for TSE infection in blood. Detection of PK-resistant PrPSc has been extensively used as a biochemical marker for TSE infectivity. However, when this project was started it was not known if PKresistant PrPSc was present in TSE-infected sheep blood in sufficient quantities to explain the infectivity levels shown by bioassay. Following the development of an optimised Western blot method, this project has demonstrated that the pattern of protein detected with novel anti-PrP monoclonal antibodies is very different from the conventional triple banded pattern of PK-resistant PrPSc. High molecular weight bands were apparent in phosphotungstic acid (NaPTA) concentrated scrapie-infected and uninfected blood and may represent a novel form of blood-specific PrP. PK-resistant PrPSc is not therefore a suitable marker for TSE infection in blood. Other proteins in TSE infected blood were also investigated. Using a proteomics approach three protein markers, lactate dehydrogenase, elongation factor 1 and annexin 1 had altered expression patterns in scrapie infected blood. These proteins, in addition to the novel forms of PrP found in blood, may provide new information on the mechanisms of pathogenesis in scrapie-infected sheep and might prove to be useful molecular indicators of diagnostic value.
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Štěpánek, Jan. "Návrh konstrukce křídla a podvozku kluzáku TST 14 MC." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2009. http://www.nusl.cz/ntk/nusl-228596.
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Modification of TST-14 MC glider, calculation of flight envelope, distribution of lift on the wing, calculation of loading cases of the wing, strength check of choosen construction nodes, design of the landing gear retraction mechanism, setting up loading of landing gear according to ULKM, strength check of landing gear
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Lizardo, Huerta Juan Carlos. "Étude théorique des mécanismes de combustion des alcènes à basse température." Thesis, Université de Lorraine, 2015. http://www.theses.fr/2015LORR0015/document.
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Ce travail de thèse a porté sur l'étude des réactions unimoléculaires de décomposition des alcènes à basse température. L'oxydation de ces molécules est primordiale dans la compréhension des mécanismes de combustion, car elles peuvent être présentes initialement dans des carburants usuels ou formées en tant qu'intermédiaires dans le processus d'oxydation. L’étude théorique menée peut se décomposer en deux parties : - L’étude des réactions de décomposition des radicaux hydroxyalkylperoxyles (HOROO•) obtenus à partir de l’addition d’un radical •OH sur l’alcène, suivi par une addition du radical •ROH sur l’oxygène moléculaire. Cette étude a été conduite de façon systématique sur un ensemble de radicaux représentatifs d'alcènes afin de mettre en évidence l'influence de l'environnement intramoléculaire sur les constantes de vitesse. Les résultats obtenus ont montré l’influence très nette de certains paramètres comme la présence d'un groupement hydroxyle en position β par rapport à l'atome de carbone réactif, la nature des atomes de carbone portant les hydrogènes transférés, la taille des cycles de transition ou encore la présence d'une liaison hydrogène intramoléculaire. - L’étude des réactions de décomposition unimoléculaires des radicaux allylperoxyles obtenus à partir de l’addition des radicaux allyliques sur l’oxygène. La grande complexité de ces systèmes a été mise en avant au cours de ce travail. Il a ainsi pu être mis en évidence que la formation d'un composé de type 1-alcenyloxirane est favorisée à basse température ce qui montre l'importance de ces réactions, souvent négligées dans les modèlesThis work focused on the study of the unimolecular decomposition of the low-temperature reactions of alkenes. The oxidation of these molecules is essential in the understanding of the mechanisms of combustion, because they are initially present in conventional fuels or formed as intermediates in the oxidation process. The theoretical study can be divided in two parts: - The study of the decomposition of hydroxyalkylperoxyl radicals (HOROO•) obtained from the addition of an •OH radical on the alkene, followed by a subsequent addition of the formed radical •ROH on molecular oxygen. This study was conducted in a systematic way on a set of representative radicals of alkenes in order to highlight the influence of the intramolecular environment on the rate constants. The results clearly showed the major influence of parameters such as the presence of a hydroxyl group in β position with respect to the reactive carbon atom, the nature of the carbon atoms bearing the transferred hydrogen, the size of the transition state ring and the presence of intramolecular hydrogen bonds. - The study of the unimolecular decomposition of the allylperoxy radicals obtained from the addition of a resonance-stabilized radical on molecular oxygen. The complexity of these systems, specifically induced by the mesomeric structures of heavy allyl radicals and the role of cis and trans conformations alkenes parents, have been highlighted in this work. It has been shown that the formation of a compound 1-alkenyloxirane is favored at low-temperatures, which shows the importance of these reactions, usually neglected in the kinetic models for the combustion of alkenes
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Ait, Hssaine Bouchra. "Spatialisation des flux d'énergie et d'eau : combinaison de la modélisation des échanges de surface-atmosphère et de la télédétection optique, thermique et micro-ondes." Thesis, Toulouse 3, 2019. http://www.theses.fr/2019TOU30093.
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Une estimation précise de l'évapotranspiration (ET) à grand échelle est une priorité pour comprendre les interactions sol-atmosphère, particulièrement dans les zones semi-arides. La télédétection fournit des informations très pertinentes à grande échelle pour alimenter les modèles d'ET. Généralement, trois variables dérivées de la télédétection sont utilisées pour déterminer la distribution spatiale de l'ET : l'humidité du sol en surface (SM) dérivée des données micro-ondes, la température de surface (LST) dérivée des données infrarouges thermiques et les indices de végétation (ou fraction de couvert fc,) issus des réflectances visible/proche infrarouge. Cependant, très peu d'études ont tenté de combiner les trois variables dans un même modèle ET. Dans ce contexte, l'objectif principal de cette thèse est d'améliorer l'estimation de l'ET en combinant la modélisation par télédétection optique /micro-ondes à multiples résolutions et la modélisation des échanges surface-atmosphère. Dans la première partie, le modèle de bilan d'énergie à double source (TSEB) basé sur les données de LST, fc et le coefficient de Priestley Taylor (αPT) qui relie l'ET au le rayonnement net est testé sur une zone hétérogène à Niamey, Niger (Wankama). Les prédictions du modèle en terme de flux de chaleur latente (LE) et sensible (H) sont comparées aux données acquises par un scintillomètre à grande ouverture (LAS) installé sur un transect d'environ 3,2 km couvrant trois types de végétation (mil, savane et jachère). Les résultats obtenus pour H et LE sont pertinents. Cependant, une surestimation des flux simulés à la fin de la saison est remarquée. Ce qui est principalement due à la valeur de αPT (fixé généralement à 1,26). Dans la 2ème partie, un nouveau modèle appelé TSEB-SM dérivé du formalisme TSEB a été développé en utilisant, en plus des données LST et fc, les données de SM comme une contrainte supplémentaire sur l'évaporation du sol. Une calibration innovante est proposée pour extraire trois paramètres clés : le coefficient de Priestley Taylor (αPT) et les paramètres (arss and, brss) de la résistance du sol. En pratique, arss et brss sont extraits à l'échelle saisonnière à partir des données SM et LST avec fc inférieur à un seuil donné fc,thres(fc,thres = 0.5), tandis que αPT est inversé à la échelle journalière à partir des données SM et LST pour fc> fc,thres. Le modèle TSEB-SM est testé sur une parcelle de blé inondée et 2 parcelles de blé irriguées en goutte-à-goutte en utilisant les données in-situ collectées lors de deux expériences expérimentales en 2002-2003 et en 2016-2017 dans le bassin versant du Tensift. L'insertion de la résistance du sol dans le modèle TSEB améliore l'estimation de l'évaporation du sol et, par conséquent, améliore la partition de l'ET. L'analyse de la série temporelle indique que αPT suit principalement la phénologie de la culture de blé, avec une valeur maximale correspondant au développement complet de la biomasse verte et une valeur minimale atteinte à la récolte. Finalement, TSEB-SM est appliqué à l'état réel en utilisant les données MODIS LST et fc à 1 km de résolution et les données SM issu de satellite SMOS (Soil Moisture and Ocean Salinity) désagrégées à l'aide d'un algorithme de désagrégation (DisPATCh) à 1 km de résolution. L'approche est validée sur une période de quatre ans (2014-2018) sur une parcelle de blé pluvial dans le bassin du Tensift, au Maroc. La parcelle a été semée pour la saison agricole 2014-2015 (S1), 2016-2017 (S2) et 2017-2018 (S3), alors qu'elle n'était pas labouré (sol nu) pendant la saison 2015-2016 (B1). La contrainte appliquée sur l'évaporation du sol en utilisant le SM dérivé des données SMOS est l'un des principaux facteurs de contrôle de la fraction évaporative, ce qui permet de déterminer avec plus de précision la partition LE/H. De plus, αPT inversé augmente après les événements pluvieux, suggérant un lien avec la disponibilité en eau du sol dans la zone racinaireA precise estimate of evapotranspiration (ET) at the landscape scale remains a priority to understand land-atmosphere-interactions, especially over semi-arid lands. Regarding data availability over large areas and at multiple scales, remote sensing observations provide very relevant information to feed ET models. Commonly, there are three main variables, derived from remote sensing, that can be used to determine the spatial distribution of ET: the surface (0-5 cm) soil moisture (SM) derived from microwave data, the land surface temperature (LST) derived from thermal infrared radiances and vegetation indices (or fractional vegetation cover fc) derived from visible/near infrared reflectances. However, very few studies have attempted to combine all three variables within a single ET model. In this context, the main objective of this thesis is to improve the estimation of ET by combining multi-resolution optical/microwave remote sensing and surface-atmosphere exchange modelling. In the first part, the thermal-based two-source energy balance (TSEB) model based on LST, fc and the Priestley Taylor (PT) coefficient (αPT) relating ET to the net radiation is tested over an heterogeneous watershed in Niamey, Niger (Wankama catchment). The model predictions of area-averaged latent (LE) and sensible (H) heat fluxes are compared to data acquired by a Large Aperture Scintillometer (LAS) set up over a transect about 3.2 km-long and spanning three vegetation types (millet, fallow and degraded shrubs). The results obtained for H and LE are relevant. However, an overestimation of simulated fluxes is recorded at the end of the season. This is mainly due to the fixed maximum value for αPT (generally set to 1.26). In the second part, a new model named TSEB-SM derived from the TSEB formalism is developed by using, in addition to LST and fc data, the near-surface SM as an extra constraint on soil evaporation. An innovative calibration procedure is proposed to retrieve three key parameters: the Priestley Taylor coefficient (αPT) and the parameters (arss and, brss) of a soil resistance formulation. In practice, arss and brss are retrieved at the seasonal time scale from SM and LST data with fc lower than a given threshold fc,thres(fc,thres is set to 0.5), while αPT is retrieved at the daily time scale from SM and LST data for fc> fc,thres. TSEB-SM model is tested over 1 flood- and 2 drip-irrigated wheat fields using in situ data collected during two field experiments in 2002-2003 and 2016-2017 in the Tensift watershed, central Morocco. The coupling of the soil resistance formulation with the TSEB formalism improves the estimation of soil evaporation, and consequently, improves the partitioning of ET. Analysis of the retrieved time series indicates that the daily αPT mainly follows the phenology of winter wheat crop with a maximum value coincident with the full development of green biomass and a minimum value reached at harvest. Finally, TSEB-SM is applied in real-life using 1 km resolution MODIS LST and fc data and the 1 km resolution SM data disaggregated from SMOS (Soil Moisture and Ocean Salinity) observations by using a disaggregation algorithm (DisPATCh). The approach is validated during a four-year period (2014-2018) over a rainfed wheat field in the Tensift basin, central Morocco. The field was seeded for the 2014-2015 (S1), 2016-2017 (S2) and 2017-2018 (S3) agricultural season, while it remained under bare soil conditions during the 2015-2016 (B1) wheat seasons. The constraint applied on the soil evaporation by using the SM derived from SMOS data is one of the main controlling factors of the evaporative fraction, which helps determine with more accuracy the LE/H partitioning. Moreover, the retrieved αPT increases after rainfall events, suggesting a relationship with the soil water availability in the root zone
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Lundin, Gustav. "Development of Graphical User Interface for the TSE test framework." Thesis, University West, Department of Technology, Mathematics and Computer Science, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:hv:diva-573.
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Williams, Roxanne. "Short and long-term performance of Canadian TSE-listed acquirers." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/MQ59292.pdf.
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顔錦基 and Kam-kee Gordon Ngan. "Re-linking the community: Haiphong road temporary market in TST." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2002. http://hub.hku.hk/bib/B31986730.
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Ngan, Kam-kee Gordon. "Re-linking the community : Haiphong road temporary market in TST /." Hong Kong : University of Hong Kong, 2002. http://sunzi.lib.hku.hk/hkuto/record.jsp?B25949779.
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Costa, Tatiana Cesarina Tôrres. "A súmula 331 do TST como instrumento de precarização laboral." Universidade Católica de Pernambuco, 2010. http://tede2.unicap.br:8080/handle/tede/892.
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Il seguente lavoro ha come tema “la sintesi 331 del TST come uno strumento precarizzazione del lavoro”. Il titolo scelto è stato il risultato delle preoccupazioni dell'autore, per quanto riguarda le modifiche avvenute nel rapporto di lavoro. Il metodo utilizzato in questo lavoro, con l'aiuto di libri, riviste e ricerche, è stato quello deduttivo. In un primo momento, l'autore fa un'analisi dei diritti e principi fondamentali del lavoratore. Successivamente, sono stati analizzati alcuni dei modi attuali e atipici di assunzione di lavoratori, frutti di politiche più flessibilizzanti, con particolare attenzione sulla terziarizzazione e la sumula 331 del Tribunale Superiore del Lavoro. Durante lo studio, l'autore farà un collegamento tra questi temi in un tentativo di dimostrare che la terziarizzazione, fondata in base al suo strumento legislativo (sumula 331 della Tribunale Superiore del Lavoro), raggiunge negativamente i diritti e i principi del lavoratore, scuotendo l'intera struttura di protezione che cade su di esso. Come potrà essere analizzato, dopo molte indagini, notasi che la terziarizzazione, legittimamente riconosciuta dallo Stato, attraverso la corte del lavoro più alta del paese, è in contrasto con principi costituzionali di applicabilità ai lavoratori, così come ai suoi fondamentali diritti legali.
O trabalho que segue tem como tema “a súmula 331 do TST como instrumento de precarização laboral”. O título escolhido foi fruto de inquietações próprias do autor, no que concerne às modificações pelas quais vem passando a relação de trabalho. O método utilizado neste trabalho, com o auxílio de livros, periódicos e pesquisas, foi o dedutivo. A princípio, o autor faz uma análise acerca dos direitos e princípios fundamentais do trabalhador. Posteriormente, foram analisadas algumas das formas atuais e atípicas de contratação de trabalhadores, frutos de políticas flexibilizadoras, com foco especial sobre a terceirização e a súmula 331 do Tribunal Superior do Trabalho. No decorrer do estudo, o autor fará um liame entre esses assuntos, numa tentativa de demonstrar que a terceirização, fundada no seu instrumento normativo (Súmula 331 do Tribunal Superior do Trabalho), atinge, de forma negativa, os direitos e princípios do trabalhador, abalando com toda a estrutura de proteção que sobre ele recai. Como poderá ser analisado, após muitas investigações, constata-se que a terceirização, legitimamente reconhecida pelo Estado, através da mais alta corte trabalhista do país, contraria princípios constitucionais de aplicabilidade para os trabalhadores, bem como direitos jusfundamentais.
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Glaysher, Bridget R. "The role of draining lymphoid tissues in TSE agent neuroinvasion." Thesis, University of Edinburgh, 2007. http://hdl.handle.net/1842/29781.
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The aims of this thesis were to determine the importance of draining lymphoid tissue in the pathogenesis of the ME7 strain of scrapie agent after inoculation via the oral, scarification or intra-peritoneal (i.p.) routes. The formation of most lymphoid tissue is critically dependent on lymphotoxin (LT) αβ signalling through LTβR during gestation. Mice in which this signalling has been interrupted lack various lymphoid tissues. After oral inoculation Peyer’s patches (PPs) within the intestine were found to be crucial for pathogenesis as mice lacking PPs did not develop disease. Isolated lymphoid follicles (ILFs) have recently been described in the murine small intestine and are thought to compensate for PP deficiency. ILFs were found to contain FDCs and support neuroinvasion of the scrapie agent in the absence of PPs. Mice lacking inguinal lymph nodes (ILNs) displayed decreased susceptibility to scrapie disease after inoculation via scarification of the skin of the thigh. This demonstrated that the ILNs are important, but neuroinvasion could occur from other tissues in some cases. The parathymic lymph nodes (ptLNs) drain the peritoneal cavity. LTα-/- mice and LTβ-/- mice lack these nodes. LTα-/- mice were less susceptible and had delayed onset of disease compared to WT mice whereas LTβ-/- mice were as susceptible and developed disease in the same time frame as WT mice after i.p. inoculation. This demonstrated that the ptLNs are dispensable for neuroinvasion via the i.p. route, but raised the possibility that lymphoid tissue present in LTβ-/- mice and absent from LTα-/- mice was important in supporting neuroinvasion. In all three routes the lack of draining lymphoid tissue had an effect on the pathogenesis of disease demonstrating the importance of these tissues in the peripheral pathogenesis of TSEs.
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Savickis, Antanas. "Konfucianistinės - maoistinės pedagogikos vertybių ir principų hermeneutinė interpretacija." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2010. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2010~D_20100903_092854-86020.
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Šiame darbe nagrinėjamos pagrindinės konfucianizmo – maoizmo moralinės padegogikos idėjos bei vertybės. Konfucianistinės – maoistinės pedagogikos idėjos Vakaruose yra klaidingai traktuojamos ir privalo būti išverstos / perkeltos į mūsų suvokimui artimesnes formas. Pirmojoje darbo dalyje nuodugniai aprašomas hermeneutinio rato metodas bei intersubjektyvumo teorija, leidžianti tyrimo metu įgyjamą asmeninį suvokimą perkelti kitiems ugdymo sistemos dalyviams. Antrojoje dalyje aprašomos Kinijos idėjinių lyderių pamatinės idėjos, stengiamasi išskirti pagrindines jų, pateikti asmeniniu sovokimu grindžiamą interpretaciją. Trečioji dalis skirta konfucianizmą – maoizmą nagrinėjusių Vakarų autorių idėjų nagrinėjimui, pasitelkiant darbo metu įgytą suvokimą. Šiame darbe paaiškėjo, kad Vakarų mokslininkai neretai klaidingai interpretuoja Kinijos pamatines ugdymo idėjas; kad Kinijos idėjinių lyderių idėjos gali būti traktuojamos kaip vientisa, vieninga sistema.In this work is analyzed basic ideas and values of confucianistic – maoistic moral pedagogy. Confucianistic – maoistic moral pedagogy ideas is wrongly perceived in Western countries and demands peculiar translation / transfer to forms, appropriate to our perception. In the first part of work is described in detail method of hermeneutic circle and theory of intersubjectivity, which allows personal knowing transfer to other members or certain educational system. In second part are presented main Chinese principled leaders educational ideas. Efforts were made to exclude main ideas, give personal interpretation for them. Third part is intended to analize Western authors, who were writing about confucianistic – maoistic theories, by using new gained perception. This work showed that often Western scientists quite skin-deep assess Chinese main educational ideas; the ideas of Chinese leaders can be understood in a way of united, integral system.
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Herrera, Alfa. "Staphylococcus aureus TSST-1 and Beta-toxin contribute to infective endocarditis via multiple mechanisms." Diss., University of Iowa, 2016. https://ir.uiowa.edu/etd/5775.
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Staphylococcus aureus is a gram positive bacterium asymptomatically colonizing 30-40% of the human population. S. aureus causes a variety of infections including superficial skin lesions, toxic shock syndrome, and infective endocarditis (IE). There are 100,000 cases of IE each year in the United States. IE is a life threatening infection of native/prosthetic valves and the lining of the heart. It is characterized by the formation of vegetations, “cauliflower-like” structures composed of bacteria and host factors. S. aureus is the most commonly identified pathogen (up to 40%) in patients with IE. USA200 (Clonal Complex 30) strains of S. aureus are significantly associated with IE, all of which produce toxic shock syndrome toxin-1 (TSST-1) and β-toxin.
TSST-1 characterizes the staphylococcal Group I superantigens (SAgs). The major mechanism of activity of TSST-1 and other SAgs is the ability to activate T-cells and APCs by non-specifically cross-bridging Vβ-chains of T-cell receptors (TCRs) with α and/or β-chains of major histocompatibility complex II (MHCII) molecules on antigen presenting cells (APCs). In a rabbit model of IE and sepsis, TSST-1 is critical for the development of vegetations and the associated colony forming units (CFUs). β-toxin has a molecular mass of 35 kDa, a basic pI (>10.0), and is a member of the DNase I superfamily. This cytotoxin has two distinct mechanisms of action: sphingomyelinase (SMase) activity and DNA biofilm ligase activity. β-toxin is critical for causing IE in a rabbit model that strongly resembles human disease. This toxin association had been observed, but studies have not been completed to determine what role TSST-1 and β-toxin play independently and in cooperation with one another, and more specifically which mechanism each uses, during IE infections.
While TSST-1 and β-toxin are both important for IE, they are very different toxins. My studies determined that the presence of TSST-1 and β-toxin in combination results in the highest levels of lethality in a rabbit model of IE. A strain expressing TSST-1 lacking superantigenic activity has decreased lethality compared to the same strain expressing wild type TSST-1. My study is the first to begin characterization of the DNA biofilm ligase active site by identifying important residues via a DNA binding and biofilm formation assays. Furthermore, my research shows that a β-toxin mutant lacking SMase activity is decreased in lethality and vegetation formation compared to wild type. β-toxin mutants disrupted in biofilm ligase activity do not decrease lethality but are deficient in vegetation formation compared to wild type. Utilizing in vitro assays to assess cellular events during IE, I established that β-toxin causes changes to morphology and is cytotoxic to human aortic endothelial cells (HAECs), inhibits production of IL-8, and modulates the expression levels of cluster of differentiation 40 (CD40) and vascular cell adhesion molecule 1 (VCAM-1).
My work shows these two virulence factors (TSST-1 and β-toxin) produced by USA200 strains and other clonal groups play important roles in causing IE.
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Penttinen, Daniel. "Lärarerfarenhet och dess påverkan på self-efficacy : en kvantitativ studie om erfarenhet, self-efficacy och personlighet bland gymnasielärare." Thesis, Linnéuniversitetet, Institutionen för psykologi (PSY), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-70479.
Full textAbstract:
Den här studien undersökte relationen mellan erfarenhet inom läraryrket och generell selfefficacy samt lärarself-efficacy. Därefter undersöktes även personlighetsegenskaper för att förstå hur self-efficacy fungerar mellan olika personer. Detta blev möjligt genom att utföra en enkätundersökning som skickades ut till lärare i gymnasieskolan (N = 94), vilket involverade General Self-Efficacy Scale (GSES), Teachers’ Sense of Efficacy Scale (TSES) och Big Five Inventory (BFI). Tidigare studier har visat blandade resultat, där lärarerfarenhet har korrelerat med generell- och lärarself-efficacy, men även studier som inte visar någon korrelation alls. Resultaten till denna studie visade signifikanta korrelationer mellan lärarself-efficacy och erfarenhet, liksom lärarself-efficacy och generell self-efficacy. Dessutom visades signifikanta korrelationer mellan alla personlighetsegenskaper och båda self-efficacies. Denna studies viktigaste slutsatser var det stigande förhållandet mellan lärarself-efficacy och erfarenhet, där längre erfarenhet resulterar i högre grad av lärarself-efficacy.
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Hauta, Nolan Andrew. "Aaron Perrine’s It has to be beautiful: concerto for alto saxophone and wind ensemble – an analysis, conductor’s guide, and soloist’s guide." Diss., University of Iowa, 2019. https://ir.uiowa.edu/etd/6758.
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Al-Harbi, Adel Mohanna. "Challenges of tuberculosis prevention through early detection of latent tuberculosis infection in new immigrants to the State of Kuwait." Thesis, University of Edinburgh, 2012. http://hdl.handle.net/1842/8939.
Full textAbstract:
Introduction: Despite management advances worldwide, tuberculosis still remains a serious uncontrolled disease. The absence of either a ‘gold’ standard diagnostic test, or a conventional rapid ‘reference’ laboratory test for asymptomatic Mycobacterium tuberculosis (MTB) carriers complicates disease control. Through mandatory screening of high-risk groups, early diagnosis of latent tuberculosis infection (LTBI) cases allows recognition and better control of the tuberculosis pandemic. Materials and Methods: The current tuberculosis screening guidelines as recommended by the World Health Organization, chest X-ray and tuberculin skin test were assessed and revealed rises in TB morbidity and fatality trends in the Kuwait population (low incidence country). In order to evaluate options for LTBI diagnosis, the current work implemented a 4-month prospective, observational, repeated-measure and randomly implemented survey on 180 new immigrants to Kuwait using a structured risk factor questionnaire whilst, simultaneously evaluating the performance of the two standard diagnostics (chest X-ray and tuberculin skin test) with the new biomarker interferon gamma release assays (T-SPOT .TB test and QuantiFERON Gold In-Tube test (QNF-GIT)); which detect the release of interferon gamma (INF-γ) released from sensitization to specific MTB antigens. Results: Associations between various epidemiological risk factors - such as socio-demographic status, smoking and environmental exposure-contact - were associated in the laboratory diagnosed LTBI participants. Positive identification of LTBI prevalence detected by two radiologists was 10.1% having ‘moderate’ inter-reader agreement (Kappa = 0.505), compared to no positives being detected by three pulmonologists. TST results were negative (less than 10-mm ‘cut-off’) even in the 86.1% Bacillus Calmette-Guérin vaccinated expatriates. Estimated LTBI using QNFGIT was 28.3% compared to 41.1% positive T-SPOT .TB test. Both interferon gamma assays revealed concordant ‘abnormal’ results in 26.1% with ‘good’ agreement (kappa = 0.627). Conclusion: Detection of latent tuberculosis infection can be facilitated by introducing evidence-based diagnostic classification depending on history taking of epidemiological-related risk factors and chest X-ray plus either interferon gamma assays.
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Rößler, Dirk, Frank Krüger, and Matthias Ohrnberger. "Rupture propagation of recent large TsE off-coast Sumatra and Java." Universität Potsdam, 2007. http://opus.kobv.de/ubp/volltexte/2007/1303/.
Full textAbstract:
The spatio-temporal evolution of the three recent tsunamogenic earthquakes (TsE)
off-coast N-Sumatra (Mw9.3), 28/03/2005 (Mw8.5) off-coast Nias, on 17/07/2006
(Mw7.7) off-coast Java. Start time, duration, and propagation of the rupture are
retrieved. All parameters can be obtained rapidly after recording of the first-arrival phases in near-real time processing. We exploit semblance analysis, backpropagation and broad-band seismograms within 30°-95° distance. Image enhancement is reached by stacking the semblance of arrays within different directions.
For the three events, the rupture extends over about 1150, 150, and 200km,
respectively. The events in 2004, 2005, and 2006 had source durations of at least 480s, 120s, and 180s, respectively. We observe unilateral rupture
propagation for all events except for the rupture onset and the Nias event, where there is evidence for a bilateral start of the rupture. Whereas average rupture speed of the events in 2004 and 2005 is in the order of the S-wave speed (≈2.5-3km/s), unusually slow rupturing (≈1.5 km/s) is indicated for the July 2006 event.
For the July 2006 event we find rupturing of a 200 x 100 km wide area in at least 2 phases with propagation from NW to SE. The event has some
characteristics of a circular rupture followed by unilateral faulting with
change in slip rate. Fault area and aftershock distribution coincide. Spatial and temporal resolution are frequency dependent. Studies of a Mw6.0 earthquake on 2006/09/21 and one synthetic source show a ≈1° limit in resolution.
Retrieved source area, source duration as well as peak values for semblance and
beam power generally increase with the size of the earthquake making possible an
automatic detection and classification of large and small earthquakes.
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LING, WU PI, and 吳碧玲. "The Determinants of GTSM-TSEC Transfer." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/58994327823402584396.
Full textAbstract:
碩士國立臺北大學
會計學系
97
This research is to study the decisive factors for an OTC trading company to turn into public listed company. By analyzing the companies successfully turned their stocks from OTC trading to Public Listing and those who are qualified between 1995 and 2004 in the aspects of funds demand, R & D, Concentration of shareholding, Profitability, Growth, Scale, Age, Industry and the review system to see if difference in any one or more aspects are interpretable to the decision of OTC-Turn-Public Listing, so as to infer the decisive factors in their going public. Furthermore, the qualification and conditions for going public of OTC trading are compared with the samples of companies not intended for public listing. Result of the research indicated that the funds need, growth, simplified review system are having positive effect on OTC trading companies to turn on public listing. They will select the timing to turn into public listing where the profitability is better, and company of smaller scale has higher incentive in turning into public listed; however, the ages of the companies are not affecting the decision of going public.
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Fang, Show-yeun, and 方秀月. "Contrarian Profit in TSE." Thesis, 1997. http://ndltd.ncl.edu.tw/handle/73428318218896537851.
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YUAN, CHANG-RUI, and 袁長瑞. "(The Research On Lao-tse)." Thesis, 1991. http://ndltd.ncl.edu.tw/handle/90185281135797397721.
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Huang, Hui-Lin, and 黃蕙玲. "The arbitrage strategy empirical analysis between TSE Electronic Sector Index Futures and TSE Electronic Sector stock." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/01720575415358180245.
Full textAbstract:
碩士國立高雄第一科技大學
財務管理所
93
The subject of this research is to analyze the performance of arbitrage Between TSE Electronic Sector Index Futures and TSE Electronic Sector stock . This research selects 20 top electronic sector value weighted stocks in MSCI Taiwan Stock Index Futures, 20 top electronic sector value weighted stocks in ETF50, and 20 top electronic sector value weighted stock in Electronic Sector Index Futures, as main sources of electronic stock constituents to run the simulating portfolio of Electronic Sector Index. These three sets are each first run to compare the correlation coefficient Between the simulating portfolio of Electronic Sector Index and Electronic Sector Index Futures to make sure if those data are functional. Then by Excel’s statistic software to utilize liner regression method to calculate out the optimal hedging volume, and these three stock index simulating portfolio’s individual stock transaction volume will be adjusted to match hedge ratio nearing contract volume. Finally, to calculate out each set’s arbitrage profit and loss by running simulating empirical test with data of 2003. The results of this research are: (1) according to above three sets’ data of 2003, the correlation coefficient between the 10 days simulating Electronic Sector stock portfolio’s return and the return of 10 days Electronic Sector Index Futures are higher then their 5 days correlation coefficient. Both the 5 days return correlation coefficient is higher than their next day’s return correlation coefficient.(2) The constituents of Electronic Sector Index Futures are very high to 274 stocks. Thus, the above three sets simulating Electronic Sector Index portfolio weighted to constituents of Electronic Sector Index Futures, excepting the 3rd set which using the top 20 electronic sector value weighted stocks as the constituents is high weighted to 66.97%, MSCI Taiwan Stock Index Futures and ETF two sets are each weighted to 53.13% and 52.7%. Therefore, the simulating error is high. (3) The empirical result shows that there are 4 times of arbitrage opportunities in 2004. The best performance of the arbitrage between TSE Electronic Sector Index Futures and TSE Electronic Sector stock is based on 20 top electronic sector value weighted stock in Electronic Sector Index Futures. The average performance is 0.91%（net gain in one year / all input cash flow in one year）. The other two investment portfolios are based on 20 top electronic sector value weighted stocks in MSCI Taiwan Stock Index Futures and 20 top electronic sector value weighted stocks in ETF50. Both the performance of arbitrage is not qualified; the average performance is just 0.38% and -0.012%. Thus by the arbitrage empirical result, the 3rd set which using the top 20 electronic sector value weighted stocks the simulating effect is good. But the simulating effect of the other two sets is not qualified. In summary, the gap of the arbitrage between Index Futures and TSE Electronic Sector stock is not notable.
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Chiu, Wen-Chao, and 邱文昭. "The Study of TSEC Taiwan Index by Signal Processing." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/73313426727890477549.
Full textAbstract:
碩士華梵大學
資訊管理學系碩士班
100
The experimental data used in this thesis are from the Taiwan Weighted Stock Index. Based on the signal processing technology, we proposed some methods for the research topic of the trend reversal signal in the Taiwan Weighted Stock Index. Nowadays, most stock market analysts used the market trend figures which are obtained manually for the analysis of market trend. The study in this thesis is to automatically identify the morphology of a typical representative of the stock market reversals in the type of broader market: “Head and Shoulders Top” and “Head and Shoulders Bottom”. There are 8 years data from the Taiwan Weighted Stock Index historical data. For simplicity, the two time interval data from the line graph of 3 months and 6 months are used. From these two data, we try to find out the “Head and Shoulders Top” and “Head and Shoulders Bottom” pattern. Two methods for recognizing the stock market reversal signal are proposed. These two proposed methods are called as the Template Comparison and the Turning point Comparison. According to our experiments, the method called as the Turning point Comparison could perform better than the method called as the Template Comparison for recognizing “Head and Shoulders Top” and “Head and Shoulders Bottom” patterns. According to our experimental results and analysis, we find that when the appearance of “Head and Shoulders Top” and “Head and Shoulders Bottom”, the stock market may begin to be the reversal state. When the real signals about “Head and Shoulders Top” and “Head and Shoulders Bottom” which appear once 2~3 seasons are detected, it is the best time (reference point) to buy or sell shares.
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Guey-Ju, Yu, and 余貴珠. "TSEC&OTC Analyze and Reserch for Unusual Finance." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/00414112860237945693.
Full textAbstract:
碩士輔仁大學
應用統計學研究所
91
Abstract Title of Thesis：TSEC & OTC Analyze and Research for Unusual Finance Name of Institute：Graduate Institute of Applied Statistics, College of Management, Fu Jen Catholic University Name of Student：Guey-Ju, Yu Advisor：Dr. Deng-Yuan, Hwang Total Pages：129 Key Words：Cross Holdings、Pyramid Structure、Adequate、Fair、Full Abstract： The propose of unusual finance analyze and research of TSEC & OTC . In research papers just had emphasized financial ratio. Recently, unusual finance is exploded TSEC & OTC which has resulted from financial ratio, stockholding structure, members of Board of directors. The accountant was forced to made illusion account what influenced the investor determined behaviour. This report is aware of reality capital market message and TSEC & OTC information which compare with my thesis. My thesis utilize six methods for ”eta value more than 0.1”, “to standardize three variables “,“one-way ANOVA Analysis”, “Principal Component Analysis”, “Canonical Correlation Analysis”, “ Logistic Regression Model”。 The investor and the creditor according to my thesis analysis methods that it can cut down to investing risk coefficient. The thesis would take the opportunity to offer Securities and Futures Commission , Ministry of Finance. This report regard one of the regulation as S&FCMOF standardize unusual finance TSEC & OTC .It is expected correct information to deal in secutities in security market.
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LIN, CHIA-TSEN, and 林佳岑. "The Others．Progressing–The Creation Discourse of Lin﹐ Jia-Tsen." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/5kev65.
Full textAbstract:
碩士大葉大學
設計暨藝術學院碩士班
105
In our modern society everybody is well acquainted with the application of technology, which has undeniably created a mutation in our lifestyles, with both positive and negative impacts. However, it is impossible to foresee the consequences of such mutation: therefore, the author has used display units (pixels) of the digital images (a.k.a. bitmaps) of those technology products which are most widely used by people as the hypothesis at the basis of the artistic creation. The hypothesis is as follows: people are affected by the evolution of science and technology which in turn create a mutation in human beings. However, the result of this mutation is not explicitated and is left at the imagination of those who view the final artistic product. The author completed three works by proceeding as follows: generalizing and integrating theoretical research, literature review and the author’s own life experiences and hypothesis; employing the use of colors in the creation itself as well as in the arrangement and construction of its shape; and gradually dissecting the association between the creative idea and the piece of work, thus attaining the concretization of theory and artistic creation. By drawing inspiration and creative elements from everyday life experiences and by impacting the viewer’s visual senses with the work of art, the author aims at conveying how technology is associated with the author and the viewers and how the former affects the latter.