Journal articles on the topic 'TRPM8'
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Yang, Xiao-Ru, Mo-Jun Lin, Lionel S. McIntosh, and James S. K. Sham. "Functional expression of transient receptor potential melastatin- and vanilloid-related channels in pulmonary arterial and aortic smooth muscle." American Journal of Physiology-Lung Cellular and Molecular Physiology 290, no. 6 (June 2006): L1267—L1276. http://dx.doi.org/10.1152/ajplung.00515.2005.
Full textMarshall-Gradisnik, Sonya M., Peter Smith, Ekua W. Brenu, Bernd Nilius, Sandra B. Ramos, and Donald R. Staines. "Examination of Single Nucleotide Polymorphisms (SNPs) in Transient Receptor Potential (TRP) Ion Channels in Chronic Fatigue Syndrome Patients." Immunology and Immunogenetics Insights 7 (January 2015): III.S25147. http://dx.doi.org/10.4137/iii.s25147.
Full textNilius, B., F. Mahieu, Y. Karashima, and T. Voets. "Regulation of TRP channels: a voltage–lipid connection." Biochemical Society Transactions 35, no. 1 (January 22, 2007): 105–8. http://dx.doi.org/10.1042/bst0350105.
Full textLötsch, Jörn, Dario Kringel, Gerd Geisslinger, Bruno G. Oertel, Eduard Resch, and Sebastian Malkusch. "Machine-Learned Association of Next-Generation Sequencing-Derived Variants in Thermosensitive Ion Channels Genes with Human Thermal Pain Sensitivity Phenotypes." International Journal of Molecular Sciences 21, no. 12 (June 19, 2020): 4367. http://dx.doi.org/10.3390/ijms21124367.
Full textSaito, Shigeru, and Ryuzo Shingai. "Evolution of thermoTRP ion channel homologs in vertebrates." Physiological Genomics 27, no. 3 (December 2006): 219–30. http://dx.doi.org/10.1152/physiolgenomics.00322.2005.
Full textKühn, Frank J. P., Gabriel Knop, and Andreas Lückhoff. "The Transmembrane Segment S6 Determines Cation versus Anion Selectivity of TRPM2 and TRPM8." Journal of Biological Chemistry 282, no. 38 (June 29, 2007): 27598–609. http://dx.doi.org/10.1074/jbc.m702247200.
Full textYin, Ying, Mengyu Wu, Lejla Zubcevic, William F. Borschel, Gabriel C. Lander, and Seok-Yong Lee. "Structure of the cold- and menthol-sensing ion channel TRPM8." Science 359, no. 6372 (December 7, 2017): 237–41. http://dx.doi.org/10.1126/science.aan4325.
Full textYee, Nelson S., Ada S. Chan, Julian D. Yee, and Rosemary K. Yee. "TRPM7 and TRPM8 Ion Channels in Pancreatic Adenocarcinoma: Potential Roles as Cancer Biomarkers and Targets." Scientifica 2012 (2012): 1–8. http://dx.doi.org/10.6064/2012/415158.
Full textThiel, Gerald, and Oliver G. Rössler. "Expression of the C-Terminal Domain of Phospholipase Cβ3 Inhibits Signaling via Gαq-Coupled Receptors and Transient Receptor Potential Channels." International Journal of Molecular Sciences 23, no. 17 (August 24, 2022): 9590. http://dx.doi.org/10.3390/ijms23179590.
Full textYamamura, Hisao, Shinya Ugawa, Takashi Ueda, Akimichi Morita, and Shoichi Shimada. "TRPM8 activation suppresses cellular viability in human melanoma." American Journal of Physiology-Cell Physiology 295, no. 2 (August 2008): C296—C301. http://dx.doi.org/10.1152/ajpcell.00499.2007.
Full textDu Preez, Stanley, Natalie Eaton-Fitch, Helene Cabanas, Donald Staines, and Sonya Marshall-Gradisnik. "Characterization of IL-2 Stimulation and TRPM7 Pharmacomodulation in NK Cell Cytotoxicity and Channel Co-Localization with PIP2 in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients." International Journal of Environmental Research and Public Health 18, no. 22 (November 12, 2021): 11879. http://dx.doi.org/10.3390/ijerph182211879.
Full textKayama, Yohei, Mamoru Shibata, Tsubasa Takizawa, Keiji Ibata, Toshihiko Shimizu, Taeko Ebine, Haruki Toriumi, Michisuke Yuzaki, and Norihiro Suzuki. "Functional interactions between transient receptor potential M8 and transient receptor potential V1 in the trigeminal system: Relevance to migraine pathophysiology." Cephalalgia 38, no. 5 (May 29, 2017): 833–45. http://dx.doi.org/10.1177/0333102417712719.
Full textGrolez, Guillaume P., Giorgia Chinigò, Alexandre Barras, Mehdi Hammadi, Lucile Noyer, Kateryna Kondratska, Etmar Bulk, et al. "TRPM8 as an Anti–Tumoral Target in Prostate Cancer Growth and Metastasis Dissemination." International Journal of Molecular Sciences 23, no. 12 (June 15, 2022): 6672. http://dx.doi.org/10.3390/ijms23126672.
Full textVelpula, Kiran, Katherine Shishido, Susovon Bayen, and Swapna Asuthkar. "Abstract 5670: TRPM8 ion channel role in prostate cancer: Actions as a rapid testosterone signaling receptor." Cancer Research 82, no. 12_Supplement (June 15, 2022): 5670. http://dx.doi.org/10.1158/1538-7445.am2022-5670.
Full textAndriulė, Inga, Dalia Pangonytė, Asfree Gwanyanya, Dainius Karčiauskas, Kanigula Mubagwa, and Regina Mačianskienė. "Detection of TRPM6 and TRPM7 Proteins in Normal and Diseased Cardiac Atrial Tissue and Isolated Cardiomyocytes." International Journal of Molecular Sciences 23, no. 23 (November 28, 2022): 14860. http://dx.doi.org/10.3390/ijms232314860.
Full textMajhi, Rakesh Kumar, Somdatta Saha, Ashutosh Kumar, Arijit Ghosh, Nirlipta Swain, Luna Goswami, Pratyush Mohapatra, et al. "Expression of temperature-sensitive ion channel TRPM8 in sperm cells correlates with vertebrate evolution." PeerJ 3 (October 13, 2015): e1310. http://dx.doi.org/10.7717/peerj.1310.
Full textRivera, Bastián, Matías Campos, Patricio Orio, Rodolfo Madrid, and María Pertusa. "Negative Modulation of TRPM8 Channel Function by Protein Kinase C in Trigeminal Cold Thermoreceptor Neurons." International Journal of Molecular Sciences 21, no. 12 (June 22, 2020): 4420. http://dx.doi.org/10.3390/ijms21124420.
Full textLelis Carvalho, Adriana, Annika Treyball, Daniel J. Brooks, Samantha Costa, Ryan J. Neilson, Michaela R. Reagan, Mary L. Bouxsein, and Katherine J. Motyl. "TRPM8 modulates temperature regulation in a sex-dependent manner without affecting cold-induced bone loss." PLOS ONE 16, no. 6 (June 4, 2021): e0231060. http://dx.doi.org/10.1371/journal.pone.0231060.
Full textYin, Ying, Son C. Le, Allen L. Hsu, Mario J. Borgnia, Huanghe Yang, and Seok-Yong Lee. "Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel." Science 363, no. 6430 (February 7, 2019): eaav9334. http://dx.doi.org/10.1126/science.aav9334.
Full textGonzález-Muñiz, Rosario, M. Angeles Bonache, Cristina Martín-Escura, and Isabel Gómez-Monterrey. "Recent Progress in TRPM8 Modulation: An Update." International Journal of Molecular Sciences 20, no. 11 (May 28, 2019): 2618. http://dx.doi.org/10.3390/ijms20112618.
Full textZhang, Lei, and Gregory J. Barritt. "TRPM8 in prostate cancer cells: a potential diagnostic and prognostic marker with a secretory function?" Endocrine-Related Cancer 13, no. 1 (March 2006): 27–38. http://dx.doi.org/10.1677/erc.1.01093.
Full textDe Caro, Carmen, Claudia Cristiano, Carmen Avagliano, Alessia Bertamino, Carmine Ostacolo, Pietro Campiglia, Isabel Gomez-Monterrey, et al. "Characterization of New TRPM8 Modulators in Pain Perception." International Journal of Molecular Sciences 20, no. 22 (November 7, 2019): 5544. http://dx.doi.org/10.3390/ijms20225544.
Full textMcCoy, Daniel D., Ligang Zhou, Anh-Khoi Nguyen, Alan G. Watts, Casey M. Donovan, and David D. McKemy. "Enhanced insulin clearance in mice lacking TRPM8 channels." American Journal of Physiology-Endocrinology and Metabolism 305, no. 1 (July 1, 2013): E78—E88. http://dx.doi.org/10.1152/ajpendo.00542.2012.
Full textSherkheli, Muhammad Azhar, Angela K. Vogt-Eisele, Daniel Bura, Leopoldo R. Beltrán Márques, Günter Gisselmann, and Hanns Hatt. "Characterization Of Selective TRPM8 Ligands And Their Structure Activity Response (S.A.R) Relationship." Journal of Pharmacy & Pharmaceutical Sciences 13, no. 2 (July 27, 2010): 242. http://dx.doi.org/10.18433/j3n88n.
Full textAmato, Antonella, Simona Terzo, Laura Lentini, Pierenrico Marchesa, and Flavia Mulè. "TRPM8 Channel Activation Reduces the Spontaneous Contractions in Human Distal Colon." International Journal of Molecular Sciences 21, no. 15 (July 29, 2020): 5403. http://dx.doi.org/10.3390/ijms21155403.
Full textYu, Xiaoyun, Youtian Hu, Fei Ru, Marian Kollarik, Bradley J. Undem, and Shaoyong Yu. "TRPM8 function and expression in vagal sensory neurons and afferent nerves innervating guinea pig esophagus." American Journal of Physiology-Gastrointestinal and Liver Physiology 308, no. 6 (March 15, 2015): G489—G496. http://dx.doi.org/10.1152/ajpgi.00336.2014.
Full textYang, Shilong, Xiancui Lu, Yunfei Wang, Lizhen Xu, Xiaoying Chen, Fan Yang, and Ren Lai. "A paradigm of thermal adaptation in penguins and elephants by tuning cold activation in TRPM8." Proceedings of the National Academy of Sciences 117, no. 15 (March 27, 2020): 8633–38. http://dx.doi.org/10.1073/pnas.1922714117.
Full textFernández-Peña, Carlos, and Felix Viana. "Targeting TRPM8 for Pain Relief." Open Pain Journal 6, no. 1 (March 8, 2013): 154–64. http://dx.doi.org/10.2174/1876386301306010154.
Full textGkika, Dimitra, Loic Lemonnier, George Shapovalov, Dmitri Gordienko, Céline Poux, Michela Bernardini, Alexandre Bokhobza, et al. "TRP channel–associated factors are a novel protein family that regulates TRPM8 trafficking and activity." Journal of Cell Biology 208, no. 1 (January 5, 2015): 89–107. http://dx.doi.org/10.1083/jcb.201402076.
Full textCheng, Li, Qing-Qing Luo, and Sheng-Liang Chen. "Expression of TRP Channels in Colonic Mucosa of IBS-D Patients and Its Correlation with the Severity of the Disease." Gastroenterology Research and Practice 2022 (May 29, 2022): 1–7. http://dx.doi.org/10.1155/2022/7294775.
Full textMelanaphy, Donal, Christopher D. Johnson, Maxim V. Kustov, Conall A. Watson, Lyudmyla Borysova, Theodor V. Burdyga, and Alexander V. Zholos. "Ion channel mechanisms of rat tail artery contraction-relaxation by menthol involving, respectively, TRPM8 activation and L-type Ca2+ channel inhibition." American Journal of Physiology-Heart and Circulatory Physiology 311, no. 6 (December 1, 2016): H1416—H1430. http://dx.doi.org/10.1152/ajpheart.00222.2015.
Full textVahabi, Bahareh, Brian A. Parsons, Olena Doran, Anthony Rhodes, Sarah Dean, and Marcus J. Drake. "TRPM8 agonists modulate contraction of the pig urinary bladder." Canadian Journal of Physiology and Pharmacology 91, no. 7 (July 2013): 503–9. http://dx.doi.org/10.1139/cjpp-2012-0406.
Full textVoronova, Irina P., Galina M. Khramova, Anna A. Evtushenko, and Tamara V. Kozyreva. "Effect of Skin Ion Channel TRPM8 Activation by Cold and Menthol on Thermoregulation and the Expression of Genes of Thermosensitive TRP Ion Channels in the Hypothalamus of Hypertensive Rats." International Journal of Molecular Sciences 23, no. 11 (May 29, 2022): 6088. http://dx.doi.org/10.3390/ijms23116088.
Full textJimenez, Jessica A., Eric S. McCoy, David F. Lee, and Mark J. Zylka. "The open field assay is influenced by room temperature and by drugs that affect core body temperature." F1000Research 12 (March 2, 2023): 234. http://dx.doi.org/10.12688/f1000research.130474.1.
Full textIzquierdo, Carolina, Mercedes Martín-Martínez, Isabel Gómez-Monterrey, and Rosario González-Muñiz. "TRPM8 Channels: Advances in Structural Studies and Pharmacological Modulation." International Journal of Molecular Sciences 22, no. 16 (August 7, 2021): 8502. http://dx.doi.org/10.3390/ijms22168502.
Full textKeh, S. M., P. Facer, A. Yehia, G. Sandhu, H. A. Saleh, and P. Anand. "The menthol and cold sensation receptor TRPM8 in normal human nasal mucosa and rhinitis." Rhinology journal 49, no. 4 (October 1, 2011): 453–57. http://dx.doi.org/10.4193/rhino11.089.
Full textHernández-Ortego, Pablo, Remedios Torres-Montero, Elvira de la Peña, Félix Viana, and Jorge Fernández-Trillo. "Validation of Six Commercial Antibodies for the Detection of Heterologous and Endogenous TRPM8 Ion Channel Expression." International Journal of Molecular Sciences 23, no. 24 (December 18, 2022): 16164. http://dx.doi.org/10.3390/ijms232416164.
Full textBecker, Vivien, Xin Hui, Lisa Nalbach, Emmanuel Ampofo, Peter Lipp, Michael D. Menger, Matthias W. Laschke, and Yuan Gu. "Linalool inhibits the angiogenic activity of endothelial cells by downregulating intracellular ATP levels and activating TRPM8." Angiogenesis 24, no. 3 (March 2, 2021): 613–30. http://dx.doi.org/10.1007/s10456-021-09772-y.
Full textIraci, Nunzio, Carmine Ostacolo, Alicia Medina-Peris, Tania Ciaglia, Anton M. Novoselov, Andrea Altieri, David Cabañero, et al. "In Vitro and In Vivo Pharmacological Characterization of a Novel TRPM8 Inhibitor Chemotype Identified by Small-Scale Preclinical Screening." International Journal of Molecular Sciences 23, no. 4 (February 13, 2022): 2070. http://dx.doi.org/10.3390/ijms23042070.
Full textThapa, Dibesh, Brentton Barrett, Fulye Argunhan, and Susan D. Brain. "Influence of Cold-TRP Receptors on Cold-Influenced Behaviour." Pharmaceuticals 15, no. 1 (December 28, 2021): 42. http://dx.doi.org/10.3390/ph15010042.
Full textSarria, Ignacio, Jennifer Ling, Michael X. Zhu, and Jianguo G. Gu. "TRPM8 acute desensitization is mediated by calmodulin and requires PIP2: distinction from tachyphylaxis." Journal of Neurophysiology 106, no. 6 (December 2011): 3056–66. http://dx.doi.org/10.1152/jn.00544.2011.
Full textTypolt, Oliver, and Davide Filingeri. "Evidence for the involvement of peripheral cold-sensitive TRPM8 channels in human cutaneous hygrosensation." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 318, no. 3 (March 1, 2020): R579—R589. http://dx.doi.org/10.1152/ajpregu.00332.2019.
Full textFeketa, Viktor V., Adithya Balasubramanian, Christopher M. Flores, Mark R. Player, and Sean P. Marrelli. "Shivering and tachycardic responses to external cooling in mice are substantially suppressed by TRPV1 activation but not by TRPM8 inhibition." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 305, no. 9 (November 1, 2013): R1040—R1050. http://dx.doi.org/10.1152/ajpregu.00296.2013.
Full textBoss, Kristina S., Kathleen J. Austin, and Brenda M. Alexander. "PSII-23 Aflatoxin B1 influences expression of TRPM8 in SKOV, ovarian epithelial cancer cells." Journal of Animal Science 98, Supplement_4 (November 3, 2020): 380. http://dx.doi.org/10.1093/jas/skaa278.668.
Full textJahanfar, Farhad, Laura Sadofsky, Alyn Morice, and Massimo D’Amico. "Nebivolol as a Potent TRPM8 Channel Blocker: A Drug-Screening Approach through Automated Patch Clamping and Ligand-Based Virtual Screening." Membranes 12, no. 10 (September 28, 2022): 954. http://dx.doi.org/10.3390/membranes12100954.
Full textНаумов, Денис, Denis Naumov, Дина Гассан, Dina Gassan, Ксения Килимиченко, Kseniya Kilimichenko, Евгения Афанасьева, et al. "PECULIARITIES OF TRPM8 RECEPTOR EXPRESSION IN THE RESPIRATORY TRACT OF ASTHMA PATIENTS." Bulletin physiology and pathology of respiration 1, no. 69 (October 5, 2018): 19–24. http://dx.doi.org/10.12737/article_5b96073c5711b1.83866044.
Full textTimkin, P. D., E. A. Timofeev, and E. A. Borodin. "TRPM8 ligand modification." Bulletin Physiology and Pathology of Respiration 1, no. 84 (July 9, 2022): 32–36. http://dx.doi.org/10.36604/1998-5029-2022-84-32-36.
Full textNaumov, Denis E., Olesya O. Kotova, Dina A. Gassan, Ivana Y. Sugaylo, Evgeniya Y. Afanas’eva, Elizaveta G. Sheludko, and Juliy M. Perelman. "Effect of TRPM8 and TRPA1 Polymorphisms on COPD Predisposition and Lung Function in COPD Patients." Journal of Personalized Medicine 11, no. 2 (February 8, 2021): 108. http://dx.doi.org/10.3390/jpm11020108.
Full textHossain, Mohammad, Hiroshi Ando, Shumpei Unno, Yuji Masuda, and Junichi Kitagawa. "Activation of TRPV1 and TRPM8 Channels in the Larynx and Associated Laryngopharyngeal Regions Facilitates the Swallowing Reflex." International Journal of Molecular Sciences 19, no. 12 (December 18, 2018): 4113. http://dx.doi.org/10.3390/ijms19124113.
Full textDussor, Greg, and Yu-Qing Cao. "TRPM8 and Migraine." Headache: The Journal of Head and Face Pain 56, no. 9 (September 16, 2016): 1406–17. http://dx.doi.org/10.1111/head.12948.
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