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Journal articles on the topic 'Triple T'

Author: Grafiati

Published: 4 June 2021

Last updated: 6 February 2022

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1

Kunkler, Charlotte N., Jacob P. Hulewicz, Sarah C. Hickman, Matthew C. Wang, Phillip J. McCown, and Jessica A. Brown. "Stability of an RNA•DNA–DNA triple helix depends on base triplet composition and length of the RNA third strand." Nucleic Acids Research 47, no. 14 (July 2, 2019): 7213–22. http://dx.doi.org/10.1093/nar/gkz573.

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AbstractRecent studies suggest noncoding RNAs interact with genomic DNA, forming an RNA•DNA–DNA triple helix that regulates gene expression. However, base triplet composition of pyrimidine motif RNA•DNA–DNA triple helices is not well understood beyond the canonical U•A–T and C•G–C base triplets. Using native gel-shift assays, the relative stability of 16 different base triplets at a single position, Z•X–Y (where Z = C, U, A, G and X–Y = A–T, G–C, T–A, C–G), in an RNA•DNA–DNA triple helix was determined. The canonical U•A–T and C•G–C base triplets were the most stable, while three non-canonical base triplets completely disrupted triple-helix formation. We further show that our RNA•DNA–DNA triple helix can tolerate up to two consecutive non-canonical A•G–C base triplets. Additionally, the RNA third strand must be at least 19 nucleotides to form an RNA•DNA–DNA triple helix but increasing the length to 27 nucleotides does not increase stability. The relative stability of 16 different base triplets in DNA•DNA–DNA and RNA•RNA–RNA triple helices was distinctly different from those in RNA•DNA–DNA triple helices, showing that base triplet stability depends on strand composition being DNA and/or RNA. Multiple factors influence the stability of triple helices, emphasizing the importance of experimentally validating formation of computationally predicted triple helices.

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2

Wjst, Matthias. "The Triple T Allergy Hypothesis." Clinical and Developmental Immunology 11, no. 2 (2004): 175–80. http://dx.doi.org/10.1080/10446670410001722258.

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The early induction of allergy is a complex process involving protective and destructive gene variants, environmental and nutritional co-factors as well as allergen exposure. Although critical doses, interactions and susceptible time frames have not been identified so far, late gestation and early childhood seem to be important time periods for allergic sensitization.At least three risk factors can be distinguished based on altered early Th1 lymphocyte development. First, the number of children with an inborn maturation defect may have increased since the beginning of the last century, when this condition would otherwise have had a lethal outcome without antibiotics and other modern health care (survival hypothesis). Second, another group of children in industrialized countries may have a deficit of environmental Th1 triggers during early life (hygiene hypothesis). A third factor may also be found predominantly in western societies. The prophylaxis of rickets with vitamin D has the apparent side effect of suppressing Th1 development (vitamin hypothesis).Experimental as well as epidemiological studies now provide evidence for the vitamin hypothesis, which is examined in this paper by a time-course analysis of vitamin D application in Germany. Also paper studies in Swedish anthroposophic school children, the Tristan da Cunha islanders, and Swiss, Austrian and Bavarian farmers may be linked to either excessive or absent early vitamin D exposure.

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Lin, Jie, Yan Wang, and Shaoqiang Deng. "T∗-extension of Lie triple systems." Linear Algebra and its Applications 431, no. 11 (November 2009): 2071–83. http://dx.doi.org/10.1016/j.laa.2009.07.001.

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4

Zhou, Jia, Liangyun Chen, and Yao Ma. "Generalized derivations of Lie triple systems." Open Mathematics 14, no. 1 (January 1, 2016): 260–71. http://dx.doi.org/10.1515/math-2016-0024.

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AbstractIn this paper, we present some basic properties concerning the derivation algebra Der (T), the quasiderivation algebra QDer (T) and the generalized derivation algebra GDer (T) of a Lie triple system T, with the relationship Der (T) ⊆ QDer (T) ⊆ GDer (T) ⊆ End (T). Furthermore, we completely determine those Lie triple systems T with condition QDer (T) = End (T). We also show that the quasiderivations of T can be embedded as derivations in a larger Lie triple system.

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5

Baues, H. J., and F. Muro. "Cohomologically triangulated categories I." Journal of K-Theory 1, no. 1 (January 3, 2008): 3–48. http://dx.doi.org/10.1017/is007011018jkt019.

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AbstractWe introduce cohomologically triangulated categories as triples (A,t,▽) given by an additive category A, an additive equivalence t:AA and a cohomology class ▽ in the translation cohomology H3(A,t). A stable homotopy theory C with A = HoC yields such a triple and the class of distinguished triangles in A is deduced from ▽.

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6

Baklouti, Amir. "Quadratic Jordan Triple Systems." Journal of Mathematics Research 11, no. 2 (March 4, 2019): 68. http://dx.doi.org/10.5539/jmr.v11n2p68.

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In this work, We show that every Jordan triple system can be viewed as a T&lowast;extension of another one or an ideal of co-dimension one of a Jordan triple system whose represent the T&lowast;extension of another Jordan triple system. Moreover, several result involving the structure of quadratic Jordan triple systems are given.

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Cao, Yan, Jian Zhang, and Yunan Cui. "On split Lie color triple systems." Open Mathematics 17, no. 1 (April 9, 2019): 267–81. http://dx.doi.org/10.1515/math-2019-0023.

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Abstract In order to begin an approach to the structure of arbitrary Lie color triple systems, (with no restrictions neither on the dimension nor on the base field), we introduce the class of split Lie color triple systems as the natural generalization of split Lie triple systems. By developing techniques of connections of roots for this kind of triple systems, we show that any of such Lie color triple systems T with a symmetric root system is of the form T = U + ∑[α]∈Λ1/∼ I[α] with U a subspace of T0 and any I[α] a well described (graded) ideal of T, satisfying {I[α], T, I[β]} = 0 if [α] ≠ [β]. Under certain conditions, in the case of T being of maximal length, the simplicity of the triple system is characterized.

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8

Nicholson, Ian A., and Hugh S. Paterson. "Modified T graft for triple-vessel disease." Annals of Thoracic Surgery 64, no. 2 (August 1997): 451–53. http://dx.doi.org/10.1016/s0003-4975(97)00538-9.

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9

Rudenko, A. S. "T-odd triple momentum correlations in decays." Nuclear Physics B - Proceedings Supplements 225-227 (April 2012): 260–62. http://dx.doi.org/10.1016/j.nuclphysbps.2012.02.054.

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10

Ateljevic, Irena, and Renata Tomljenovic. "Triple T: Tourism, transmodernity and transformative learning." Turisticko poslovanje, no. 17 (2016): 25–31. http://dx.doi.org/10.5937/turpos1617025a.

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11

Callan, David, Toufik Mansour, and Mark Shattuck. "Enumeration of permutations avoiding a triple of 4-letter patterns is almost all done." Pure Mathematics and Applications 28, no. 1 (October 1, 2019): 14–69. http://dx.doi.org/10.1515/puma-2015-0031.

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Abstract This paper basically completes a project to enumerate permutations avoiding a triple T of 4-letter patterns, in the sense of classical pattern avoidance, for every T. There are 317 symmetry classes of such triples T and previous papers have enumerated avoiders for all but 14 of them. One of these 14 is conjectured not to have an algebraic generating function. Here, we find the generating function for each of the remaining 13, and it is algebraic in each case.

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12

GENG, C. Q., and Y. K. HSIAO. "T VIOLATION IN BARYONIC B DECAYS." International Journal of Modern Physics A 21, no. 04 (February 10, 2006): 897–900. http://dx.doi.org/10.1142/s0217751x06032265.

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We study T violation in the three-body charmless baryonic decay of [Formula: see text] through the T-odd triple product correlation in the standard model. We find that the T violating asymmetry is 10%, which is accessible to the current B factories at KEK and SLAC, while the CP violating one 1.1%. We emphasize that this triple product correlation would be the first measurable direct T violating effect predicted in the standard model.

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13

Aoyama, S., N. Itagaki, K. Arai, K. Katō, and M. Oi. "t+t clustering in He-isotopes." Modern Physics Letters A 21, no. 31n33 (October 30, 2006): 2499–502. http://dx.doi.org/10.1142/s021773230602216x.

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t+t clustering in He isotopes is investigated by using two theoretical approaches. A role of the t+t cluster component in the ground state is examined with AMD triple-S, allowing the wider configuration space containing simultaneously the "t+t+valence neutrons" structure and "4 He +valence neutrons" structure. We understand the importance of the t + t component even for the ground state. Further, t + t resonances are investigated with RGM type approach. We obtained many t + t states as resonances near to t + t threshold.

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14

Ragnarsson, Kári. "RETRACTIVE TRANSFERS AND p-LOCAL FINITE GROUPS." Proceedings of the Edinburgh Mathematical Society 51, no. 2 (June 2008): 465–87. http://dx.doi.org/10.1017/s0013091505001719.

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AbstractIn this paper we explore the possibility of defining $p$-local finite groups in terms of transfer properties of their classifying spaces. More precisely, we consider the question, posed by Haynes Miller, of whether an equivalent theory can be obtained by studying triples $(f,t,X)$, where $X$ is a $p$-complete, nilpotent space with a finite fundamental group, $f:BS\to X$ is a map from the classifying space of a finite $p$-group, and $t$ is a stable retraction of $f$ satisfying Frobenius reciprocity at the level of stable homotopy. We refer to $t$ as a retractive transfer of $f$ and to $(f,t,X)$ as a retractive transfer triple over $S$.In the case where $S$ is elementary abelian, we answer this question in the affirmative by showing that a retractive transfer triple $(f,t,X)$ over $S$ does indeed induce a $p$-local finite group over $S$ with $X$ as its classifying space.Using previous results obtained by the author, we show that the converse is true for general finite $p$-groups. That is, for a $p$-local finite group $(S,\mathcal{F},\mathcal{L})$, the natural inclusion $\theta:BS\to X$ has a retractive transfer $t$, making $(\theta,t,|\mathcal{L}|^{\wedge}_p)$ a retractive transfer triple over $S$. This also requires a proof, obtained jointly with Ran Levi, that $|\mathcal{L}|^{\wedge}_p$ is a nilpotent space, which is of independent interest.

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15

Frankfurt, Leonid, and Mark Strikman. "Large-t, triple-pomeron diffractive processes in QCD." Physical Review Letters 63, no. 18 (October 30, 1989): 1914–16. http://dx.doi.org/10.1103/physrevlett.63.1914.

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16

Frankfurt, Leonid, and Mark Strikman. "Large-t, Triple-Pomeron Diffractive Processes in QCD." Physical Review Letters 64, no. 7 (February 12, 1990): 815. http://dx.doi.org/10.1103/physrevlett.64.815.

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17

Esposito, M., E. Covino, J. M. Alcalá, E. W. Guenther, and E. Schisano. "MO Lup: a hierarchical triple T Tauri system*." Monthly Notices of the Royal Astronomical Society 376, no. 4 (April 2007): 1805–13. http://dx.doi.org/10.1111/j.1365-2966.2007.11560.x.

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18

Maes, Koen C., and Bernard De Baets. "The triple rotation method for constructing t-norms." Fuzzy Sets and Systems 158, no. 15 (August 2007): 1652–74. http://dx.doi.org/10.1016/j.fss.2007.03.010.

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19

Raj, R. "Premelting at triple grain junctions." Acta Metallurgica et Materialia 38, no. 8 (August 1990): 1413–16. http://dx.doi.org/10.1016/0956-7151(90)90109-t.

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20

Rajhans, Raja, Sanjaya Sahu, and Mahendra Prasad Behera. "Impact of Education on the Perception of Muslim People about Instant Triple Talaq Law." Shanlax International Journal of Arts, Science and Humanities 9, no. 1 (July 1, 2021): 68–74. http://dx.doi.org/10.34293/sijash.v9i1.3857.

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The present study designed to investigate the Impact of Education in the Perception of Muslim People about Instant Triple Talaq Law. The main objectives of the study were to compare mean scores of perceptions of educated and uneducated Muslim people about Instant Triple Talaq Law, to compare mean scores of perceptions of educated male and educated female Muslim people about Instant Triple Talaq Law, and to compare mean scores of perceptions of uneducated male and uneducated female Muslim people about Instant Triples Talaq Law. For this study, 100 Muslim people were selected from Bargarh district, Odisha through stratified random sampling. A Causal comparative method was employed by the researcher. The investigator prepared a Perception Scale for collecting data. The ‘t’ test revealed that a significant difference was found in the mean scores of perceptions between educated and uneducated Muslim people towards instant triple talaq law. The findings also reveal that no significant mean difference was found between educated male and educated female and uneducated male and uneducated female Muslim people in perceiving the impact of education about Instant Triple Talaq Law.

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21

Kasper, M., K. K. R. Santhakumari, T. M. Herbst, R. van Boekel, F. Menard, R. Gratton, R. G. van Holstein, et al. "A triple star in disarray." Astronomy & Astrophysics 644 (December 2020): A114. http://dx.doi.org/10.1051/0004-6361/202039186.

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Aims. T Tauri remains an enigmatic triple star for which neither the evolutionary state of the stars themselves, nor the geometry of the complex outflow system is completely understood. Eight-meter class telescopes equipped with state-of-the-art adaptive optics provide the spatial resolution necessary to trace tangential motion of features over a timescale of a few years, and they help to associate them with the different outflows. Methods. We used J-, H-, and K-band high-contrast coronagraphic imaging with VLT-SPHERE recorded between 2016 and 2018 to map reflection nebulosities and obtain high precision near-infrared (NIR) photometry of the triple star. We also present H2 emission maps of the ν = 1-0 S(1) line at 2.122 μm obtained with LBT-LUCI during its commissioning period at the end of 2016. Results. The data reveal a number of new features in the system, some of which are seen in reflected light and some are seen in H2 emission; furthermore, they can all be associated with the main outflows. The tangential motion of the features provides compelling evidence that T Tauri Sb drives the southeast–northwest outflow. T Tauri Sb has recently faded probably because of increased extinction as it passes through the southern circumbinary disk. While Sb is approaching periastron, T Tauri Sa instead has brightened and is detected in all our J-band imagery for the first time.

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22

Vasquez, Karen M., and Peter M. Glazer. "Triplex-forming oligonucleotides: principles and applications." Quarterly Reviews of Biophysics 35, no. 1 (February 2002): 89–107. http://dx.doi.org/10.1017/s0033583502003773.

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1. Triple-helical nucleic acids 891.1 History 891.2 Use of oligomers in triplex formation 902. Modes of triplex formation 902.1 Intermolecular triplexes 902.2 Intramolecular triplexes (H-DNA) 922.3 R-DNA (recombination DNA) 922.4 PNA (peptide nucleic acids) 933. Triplex structural models 933.1 YR-Y triplexes 943.2 GT-A base triplets 943.3 TC-G base triplets 943.4 TA-T and C+G-C base triplets 943.5 RR-Y triplexes 944. Modifications of TFOs 954.1 Backbone modification of oligonucleotides 954.2 Modification of the ribose in oligonucleotides 964.3 Base modification of oligonucleotides 975. Gene targeting and modification via triplex technology 985.1 Transcription and replication inhibition 995.2 TFO-directed mutagenesis 995.3 TFO-induced recombination 1005.4 Future challenges in triplex-directed genome modification 1006. References 101The first description of triple-helical nucleic acids was by Felsenfeld and Rich in 1957 (Felsenfeld et al. 1957). While studying the binding characteristics of polyribonucleotides by fiber diffraction studies, they determined that polyuridylic acid [poly(U)] and polyadenylic acid [poly(A)] strands were capable of forming a stable complex of poly(U) and poly(A) in a 2:1 ratio. It was therefore concluded that the nucleic acids must be capable of forming a helical three-stranded structure. The formation of the three-stranded complex was preferred over duplex formation in the presence of divalent cations (e.g. 10 mm MgCl2). The reaction was quite specific, since the (U-A) molecule did not react with polycytidylic acid [(poly(C)], polyadenylic acid or polyinosinic acid [(poly(I)] (Felsenfeld et al. 1957). It was later found that poly(dT-dC) and poly(dG-dA) also have the capacity to form triple-stranded structures (Howard & Miles, 1964; Michelson & Monny, 1967). Other triple helical combinations of polynucleotide strands were identified from X-ray fiber-diffraction studies including, (A)n.2(I)n and (A)n.2(T)n (Arnott & Selsing, 1974). X-ray diffraction patterns of triple-stranded fibers of poly(A).2poly(U) and poly(dA).2poly(dT) showed an A-form conformation of the Watson–Crick strands. The third strand was bound in a parallel orientation to the purine strand by Hoogsteen hydrogen bonds (Hoogsteen, 1959; Arnott & Selsing, 1974). In 1968, the first potential biological role of these structures was identified by Morgan & Wells (1968). Using an in vitro assay, they found that transcription by E. coli RNA polymerase was inhibited by an RNA third strand. Thus, the recent developments identifying the potential of triplex formation for gene regulation and genome modification came more than 20 years after this first study of transcription inhibition by triplex formation.

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23

Zhao, Ruirui, Minxia Luo, and Shenggang Li. "Reverse triple I method based on single valued neutrosophic fuzzy inference." Journal of Intelligent & Fuzzy Systems 39, no. 5 (November 19, 2020): 7071–83. http://dx.doi.org/10.3233/jifs-200265.

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The theory of single valued neutrosophic sets, which is a generalization of intuitionistic fuzzy sets, is more capable of dealing with inconsistent information in practice. In this paper, we propose reverse triple I method under single valued neutrosophic environment. Firstly, we give the definitions of single valued neutrosophic t-representation t-norms and single valued neutrosophic residual implications. Secondly, we develop a formula for calculating single valued neutrosophic residual implications. Then we propose reverse triple I method based on left-continuous single valued neutrosophic t-representation t-norms and its solutions. Lastly, we discuss the robustness of reverse triple I method based on the proposed similarity measure.

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Dagher, Elie, Laura Simbault, Jérôme Abadie, Delphine Loussouarn, Mario Campone, and Frédérique Nguyen. "Identification of an immune-suppressed subtype of feline triple-negative basal-like invasive mammary carcinomas, spontaneous models of breast cancer." Tumor Biology 42, no. 1 (January 2020): 101042831990105. http://dx.doi.org/10.1177/1010428319901052.

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Feline invasive mammary carcinomas are characterized by their high clinical aggressiveness, rare expression of hormone receptors, and pathological resemblance to human breast cancer, especially triple-negative breast cancer (negative to estrogen receptor, progesterone receptor, and epidermal growth factor receptor type 2). Recent gene expression studies of triple-negative breast cancers have highlighted their heterogeneity and the importance of immune responses in their biology and prognostic assessment. Indeed, regulatory T cells may play a crucial role in producing an immune-suppressed microenvironment, notably in triple-negative breast cancers. Feline invasive mammary carcinomas arise spontaneously in immune-competent animals, in which we hypothesized that the immune tumor microenvironment also plays a role. The aims of this study were to determine the quantity and prognostic value of forkhead box protein P3-positive peritumoral and intratumoral regulatory T cells in feline invasive mammary carcinomas, and to identify an immune-suppressed subgroup of triple-negative basal-like feline invasive mammary carcinomas. One hundred and eighty female cats with feline invasive mammary carcinomas, treated by surgery only, with 2-year follow-up post-mastectomy, were included in this study. Forkhead box protein P3, estrogen receptor, progesterone receptor, Ki-67, epidermal growth factor receptor type 2, and cytokeratin 14 expression were assessed by automated immunohistochemistry. Peritumoral regulatory T cells were over 300 times more abundant than intratumoral regulatory T cells in feline invasive mammary carcinomas. Peritumoral and intratumoral regulatory T cells were associated with shorter disease-free interval and overall survival in both triple-negative (ER–, PR–, HER2–, N = 123 out of 180) and luminal (ER+ and/or PR+, N = 57) feline invasive mammary carcinomas. In feline triple-negative basal-like (CK14+) mammary carcinomas, a regulatory T-cell–enriched subgroup was associated with significantly poorer disease-free interval, overall survival, and cancer-specific survival than regulatory T-cell-poor triple-negative basal-like feline invasive mammary carcinomas. High regulatory T-cell numbers had strong and negative prognostic value in feline invasive mammary carcinomas, especially in the triple-negative basal-like subgroup, which might contain a “basal-like immune-suppressed” subtype, as described in triple-negative breast cancer. Cats with feline invasive mammary carcinomas may thus be interesting spontaneous animal models to investigate new strategies of cancer immunotherapy in an immune-suppressed tumor microenvironment.

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Beck, Tracy L., G. H. Schaefer, S. Guilloteau, M. Simon, A. Dutrey, E. Di Folco, and E. Chapillon. "On the Nature of the T Tauri Triple System." Astrophysical Journal 902, no. 2 (October 21, 2020): 132. http://dx.doi.org/10.3847/1538-4357/abb5f5.

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Poissonnier, A., M. Le Gallo, F. Godey, and P. Legembre. "T cell landscape in triple negative breast cancer patients." Breast 32 (March 2017): S99. http://dx.doi.org/10.1016/s0960-9776(17)30314-4.

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27

Bensalem, Wafia, Alakabha Datta, and David London. "T-violating triple-product correlations in charmless Λb decays." Physics Letters B 538, no. 3-4 (July 2002): 309–20. http://dx.doi.org/10.1016/s0370-2693(02)02028-2.

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Khaled, Md Fakhrul Islam, Md Azharul Islam, Md Abu Salim, Md Mukhlesur Rahman, Mostashirul Haque, MSI Tipu Chawdhury, Mohammed Emran, Md Walidur Rahman, and Dipal Krishna Adhikary. "Triple T pattern on ECG and Apical Hypertrophic Cardiomyopathy." KYAMC Journal 10, no. 3 (December 23, 2019): 160–63. http://dx.doi.org/10.3329/kyamcj.v10i3.44422.

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T wave on ECG is the positive deflection after QRS complex which reflect the ventricular repolarization. The amplitude of T wave is 5mm in limb lead and 10mm in chest leads. T wave is upright in all leads except a VR and V1, but it may be inverted in V1-V3 in pediatric age group. Triple T pattern is the negative T waves in inferior leads, anterior leads and on a VR. Triple T pattern is a very common finding in Apical hypertrophic cardiomyopathy (AHCM). Apical hypertrophic cardiomyopathy is a rare form of cardiomyopathy that affects LV apex and rarely RV apex or both. Patients with AHCM has a wide range of presentations, ranging from asymptomatic to palpitation, nonspecific chest discomfort, chest pain etc. It does not present with features which are common in other type of obstructive hypertrophic cardiomyopathy like presyncope, syncope, and it has less chance of sudden cardiac death. First clue of diagnosis of AHCM is widespread negative T wave in ECG. Although negative T-waves may be found in chest leads in 93% of cases. Cardiovascular magnetic resonance (CMR) is the best diagnostic tool. Proper transthoracic echocardiographic evaluation demonstrates apical wall thickness >15 mm and a ratio of maximal apical to posterior wall thickness >1.5 mm. Beta-blockers are mainstay of treatment whereas implantable cardioverter defibrillator (ICD) is recommended for high risk cases. As it is a genetic disease genetic counseling and periodic follow up is required. KYAMC Journal Vol. 10, No.-3, October 2019, Page 160-163

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Dagneaux, C., H. Gousset, A. K. Shchyolkina, M. Ouali, R. Letellier, J. Liquier, V. L. Florentiev, and E. Taillandier. "Parallel and Antiparallel A*A-T Intramolecular Triple Helices." Nucleic Acids Research 24, no. 22 (November 1, 1996): 4506–12. http://dx.doi.org/10.1093/nar/24.22.4506.

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Diebold, D., E. Y. Wang, J. Pew, G. Winz, R. Breun, W. Li, H. Y. Che, and N. Hershkowitz. "Triple Langmuir probe measurements in the Phaedrus‐T tokamak." Review of Scientific Instruments 61, no. 10 (October 1990): 2870–72. http://dx.doi.org/10.1063/1.1141810.

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Sheridan, Brian S., and Joshua J. Obar. "Editorial: Vγ9Vδ2 T cells: triple costimulation goes the distance." Journal of Leukocyte Biology 99, no. 4 (April 2016): 515–17. http://dx.doi.org/10.1189/jlb.1ce1115-522r.

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Kannanganat, Sunil, Chris Ibegbu, Lakshmi Chennareddi, Harriet L. Robinson, and Rama Rao Amara. "Multiple-Cytokine-Producing Antiviral CD4 T Cells Are Functionally Superior to Single-Cytokine-Producing Cells." Journal of Virology 81, no. 16 (June 6, 2007): 8468–76. http://dx.doi.org/10.1128/jvi.00228-07.

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ABSTRACT Virus-specific CD4 T cells are endowed with multiple functions, such as cytokine production, CD40 ligand (CD40L) expression (associated with the costimulation of CD8 and B cells), and degranulation (associated with cytotoxic potential). Here, we used antiviral CD4 T cells present in human blood to evaluate the relationship between cytokine production and other functions of CD4 T cells. Antiviral CD4 T cells specific for a virus causing persistent infection, cytomegalovirus (CMV), and two viruses causing nonpersistent infections, influenza virus and the smallpox vaccine virus (vaccinia virus), were studied. CD4 T cells specific for each of the viruses produced all seven possible combinations of the cytokines gamma interferon (IFN-γ), interleukin-2, and tumor necrosis factor alpha. Cells producing three or two cytokines (triple producers and double producers) represented nearly 50% of the total response to each of the viruses. Triple producers expressed the highest levels of cytokines per cell, and single producers expressed the lowest. Following stimulation, higher frequencies of triple producers than single producers expressed CD40L. Only CMV-specific CD4 T cells underwent degranulation. However, higher frequencies of CMV-specific triple producers than single producers showed this functional characteristic. In contrast to the functional phenotypes, the memory phenotypes of triple producers and IFN-γ single producers did not differ. These results demonstrate a strong positive association between the cytokine coproduction capacity of a virus-specific CD4 T cell and its other functional characteristics and suggest that vaccines should aim to elicit T cells that coproduce more than one cytokine.

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Bai, Zhanbing, Mingfu Ma, and Xiangqian Liang. "Triple positive solutions for the one-dimensional $p$-laplacian." Tamkang Journal of Mathematics 37, no. 1 (March 31, 2006): 15–25. http://dx.doi.org/10.5556/j.tkjm.37.2006.176.

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We consider the boundary value problem: $ \left(\varphi_p(x'(t))\right)'+ q(t)f(t, x(t), x'(t))=0, p>1, t \in [0, 1] $, with $ x(0)=x(1)=0 $, or $ x(0)=x'(1)=0 $. Using a fixed point theorem due to Avery and Peterson, sufficient conditions are obtained that guarantee the existence of at least three positive solutions. The emphasis here is the nonlinear term $ f $ is involved with the first order derivative. An example is also included to illustrate the importance of the results obtained

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TEMELSO, BERHANE, NANCY A. RICHARDSON, LEVENT SARI, YUKIO YAMAGUCHI, and HENRY F. SCHAEFER. "CHARACTERIZATION OF THE $\tilde{X}\,^2 \Pi$ AND Ã2Σ+ ELECTRONIC STATES OF THE PHOSPHAETHYNE CATION (HCP+)." Journal of Theoretical and Computational Chemistry 04, spec01 (January 2005): 707–24. http://dx.doi.org/10.1142/s0219633605001738.

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The electronic ground state [Formula: see text] and first excited state (Ã2Σ+) of phosphaethyne cation (HCP+) have been systematically investigated using ab initio electronic structure theory. The total energies, geometries, rotational constants, dipole moments, harmonic vibrational frequencies, and parameters for Renner–Teller splittings were determined using self-consistent-field (SCF), configuration interaction with single and double excitations (CISD), coupled cluster (CC) with single and double excitations (CCSD), CCSD with perturbative triple excitations [CCSD(T)], CC with single, double, and iterative partial triple excitations (CCSDT-3), and CC with single, double, and full triple excitations (CCSDT) methods and eight different basis sets. Some of the largest full triples coupled cluster computations to date are reported. Degenerate bending frequencies for the Ã2Σ+ state were determined using the equation-of-motion (EOM)-CCSD technique. The two states have been confirmed to have linear equilibrium structures. At the full CCSDT level of theory with the correlation-consistent polarized valence quadruple zeta (cc-pVQZ) basis set, the classical [Formula: see text] splitting ( T e value) is predicted to be 47.7 kcal/mol (2.07 eV, 16,700 cm-1) and the quantum mechanical splitting (T0 value) to be 48.1 kcal/mol (2.08 eV, 16,800 cm-1), which are in excellent agreement with the experimental values of T e = 47.77 kcal/mol (2.072 eV , 16,708 cm -1) and T0 = 47.94 kcal/mol (2.079 eV, 16,766 cm-1). The excitation energies predicted by the CCSDT-3 and CCSD(T) methods differ from the full triples CCSDT result by 0.38 and 0.45 kcal/mol, respectively. With the aug-cc-pVQZ CCSDT-3 method the Renner parameter and the averaged harmonic bending vibrational frequency are determined to be ∊= -0.0390 and [Formula: see text] for the ground state of HCP+, which are reasonably consistent with the experimental values of ∊=-0.0415 and [Formula: see text]. The predicted dipole moments are 1.30 Debye ([Formula: see text] state, polarity-hydrogen atom positive) and 0.06 Debye (Ã2Σ+ state, polarity-phosphorus atom positive).

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35

Bernardi, Enrico, Antonio Bove, and Vesselin Petkov. "Cauchy problem for effectively hyperbolic operators with triple characteristics of variable multiplicity." Journal of Hyperbolic Differential Equations 12, no. 03 (September 2015): 535–79. http://dx.doi.org/10.1142/s0219891615500162.

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We study a class of third-order hyperbolic operators P in G = {(t, x): 0 ≤ t ≤ T, x ∈ U ⋐ ℝn} with triple characteristics at ρ = (0, x0, ξ), ξ ∈ ℝn ∖{0}. We consider the case when the fundamental matrix of the principal symbol of P at ρ has a couple of non-vanishing real eigenvalues. Such operators are called effectively hyperbolic. Ivrii introduced the conjecture that every effectively hyperbolic operator is strongly hyperbolic, that is the Cauchy problem for P + Q is locally well posed for any lower order terms Q. This conjecture has been solved for operators having at most double characteristics and for operators with triple characteristics in the case when the principal symbol admits a factorization. A strongly hyperbolic operator in G could have triple characteristics in G only for t = 0 or for t = T. We prove that the operators in our class are strongly hyperbolic if T is small enough. Our proof is based on energy estimates with a loss of regularity.

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Corkery, B., N. O’Donovan, M. Clynes, and J. Crown. "Epidermal growth factor receptor (EGFR) inhibition in triple-negative breast cancer (BrCa)." Journal of Clinical Oncology 25, no. 18_suppl (June 20, 2007): 14071. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.14071.

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14071 Background: Triple-negative BrCa lacks expression of hormone receptors and HER-2 but does express EGFR. It is associated with early relapse and poor survival. There is no targeted therapy for triple-negative BrCa. We are studying the potential role of EGFR inhibition. Methods: EGFR expression was examined in triple-negative BrCa cell lines, (BT20, HCC1937, and MDA-MB-231) by western blot. IC50 assays were determined for three EGFR inhibitors, gefitinib (G) and erlotinib (T), which are small-molecule tyrosine kinase inhibitors, and cetuximab (E) which is a monoclonal antibody against EGFR, and chemotherapy (CRx) drugs docetaxel (D) and carboplatin (P)), using the acid phosphatase assay. The controls were HER2+ BrCa cell lines, BT474 and SKBR3 which express low levels of EGFR. Results: The three triple-negative cell lines over-express EGFR. IC50 values for G and T were significantly higher in the triple-negative than in the HER2+ cell lines. E did not cause significant inhibition in any cell line (max inhibition 20% at 100 μg/ml E). IC50 values for G were lower than for T in the triple-negative cell lines (IC50s for HCC1937: G - 8.4 ± 1.5 μM; T - 26.2 ± 9.3 μM). Combined EGFR inhibition with CRx was tested in HCC1937 cells. G combined with P or with D for 5 days showed an additive effect on inhibition of proliferation ( Table 1 ). Alternate scheduling of the drugs did not significantly influence response. Conclusions: Our results suggest that triple-negative BrCa cells over-express EGFR but are not as sensitive to EGFR inhibition as HER2+ BrCa cells. However, EGFR inhibition may enhance response to CRx in triple-negative BrCa. [Table: see text] No significant financial relationships to disclose.

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37

Martínez, Rafael, Margarita Tadeo-Robledo, Ángel Piña del Valle, Alejandro Espinosa, and Ana María Solano. "Rendimiento de nuevos híbridos PUMAS de maíz para la zona de transición de México." Agronomía Mesoamericana 10, no. 1 (June 3, 2015): 73. http://dx.doi.org/10.15517/am.v10i1.19454.

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Four new double-cross hybrids and 16 triple-cross hybrids were evaluated and compared with triple-cross commercial hybrids H-135, A- 791, PUMA 1157 and PUMA 1159, and double-cross H-137, during the 1996 spring-summer season. The purpose was to offer new and better options to producers in the Bajio and Highland Transitional Zones in Mexico (1800-2200 m.a.s.l.). Analysis of variance showed highly significant statistical differences for almost all variables for which the genotype factor was studied, and non-significant differences for repetitions. Nine triple-cross hybrids yielded between 8 and 12 t/ha, a greater yield than that of the rest of the hybrids (double and triple crosses), and also greater than that of the controls. The triple-cross UHT96E410 hybrid stood out yielding 12,4 t/ha in 77 days between sowing and tasseling. The triple-cross control A-791 followed, yielding 8.6 t/ha in 99 days between sowing and tasseling; UHT96E410 grew up to 209 cm in height. Five of the controls showed heights of over 230 cm. These new hybrids stood out for their superior yield and favorable agronomic traits, offering farmers in the transitional zones of Mexico a broader variety of options.

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38

Burgos, María, Francisco J. Fernández-Polo, Jorge J. Garcés, and Antonio M. Peralta. "ORTHOGONALITY PRESERVERS REVISITED." Asian-European Journal of Mathematics 02, no. 03 (September 2009): 387–405. http://dx.doi.org/10.1142/s1793557109000327.

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We obtain a complete characterization of all orthogonality preserving operators from a JB *-algebra to a JB *-triple. If T : J → E is a bounded linear operator from a JB *-algebra (respectively, a C *-algebra) to a JB *-triple and h denotes the element T**(1), then T is orthogonality preserving, if and only if, T preserves zero-triple-products, if and only if, there exists a Jordan *-homomorphism [Formula: see text] such that S(x) and h operator commute and T(x) = h•r(h) S(x), for every x ∈ J, where r(h) is the range tripotent of h, [Formula: see text] is the Peirce-2 subspace associated to r(h) and •r(h) is the natural product making [Formula: see text] a JB *-algebra. This characterization culminates the description of all orthogonality preserving operators between C *-algebras and JB *-algebras and generalizes all the previously known results in this line of study.

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39

Petrich, Mario. "The kernel and trace operators for ideal extensions of regular semigroups." Glasgow Mathematical Journal 36, no. 2 (May 1994): 219–31. http://dx.doi.org/10.1017/s0017089500030767.

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AbstractLet V be a regular semigroup and an ideal extension of a semigroup S by a semigroup Q Congruences on V can be represented by triples of the form (σ, P, τ), here called admissible, where a is a congruence on S, P is an ideal of Q and τ is a O-restricted congruence on Q/P satisfying certain conditions. We characterize the trace relation T on V in terms of admissible triples. When the extension V of S is strict, for a congruence v on V given in terms of an admissible triple, we characterize vK, vK, vT and vT again in terms of admissible triples.

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40

Anosova, J. P., L. G. Kiseleva, and V. V. Orlov. "On Dynamical Non-Stationarity of the Galaxy Systems." International Astronomical Union Colloquium 132 (1993): 161–69. http://dx.doi.org/10.1017/s0252921100066033.

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AbstractBy the computer simulations we have studied a behaviour of the virial coefficient k(t) for the triples and quintets of galaxies as a function of time. In a number of cases some quasiperiodical oscillations k(t) have been observed; these variations are resulted from an existence of the temporary binary subsystems. Strong negative correlation between k and rmin (rmin is a minimum separation between the bodies) is observed. A presence of a large hidden mass Mn distributed around a triple increases the degree of stochasticity of the process k(t) and decreases the correlation between k and rmin. The process k(t) must not been considered as a random one, as the autocorrelation function does not show any decreasing of the oscillation amplitude with a grow of time.

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41

ASAI, NOBUHIRO, IZUMI KUBO, and HUI-HSIUNG KUO. "THE BRENKE TYPE GENERATING FUNCTIONS AND EXPLICIT FORMS OF MRM-TRIPLES BY MEANS OF Q-HYPERGEOMETRIC SERIES." Infinite Dimensional Analysis, Quantum Probability and Related Topics 16, no. 02 (June 2013): 1350010. http://dx.doi.org/10.1142/s0219025713500100.

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An MRM-triple (h(x), ρ(t), B(t)) gives a generating function B(t)h(ρ(t)x) of some orthogonal polynomials on ℝ. In particular, B(t)h(tx) is called the Brenke type.19 In this paper, we shall determine all MRM-triples and associated Jacobi-Szegö parameters of this type with showing very careful computations in detail. (h(x), t, B(t)) is classified into four categories. In any case, h(x) and B(t) can be expressed in terms of two kinds of q-hypergeometric series, old basic and basic hypergeometric series, rΦs and rϕs, respectively. As examples, our results contain generating functions of the Al-Salam-Carlitz (I and II), little q-Laguerre, q-Laguerre, and discrete q-Hermite (I and II) polynomials. Our results are more complete and general than those of Refs. 20 and 21 by Chihara. The following are special cases of our results in each class. Here {αn, ωn} are the Jacobi-Szegö parameters. [Formula: see text]

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42

DONG, YAN-QIN, QING-CHENG ZHANG, and YONG-ZHENG ZHANG. "RESTRICTED AND QUASI-TORAL RESTRICTED LIE TRIPLE SYSTEMS." Journal of Algebra and Its Applications 11, no. 05 (September 26, 2012): 1250093. http://dx.doi.org/10.1142/s0219498812500934.

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In this paper, we first discuss the nilpotency of restricted Lie triple systems and the condition of existence of p-mappings on Lie triple systems. Second, we devote our attention to prove the uniqueness of the decomposition as a direct sum of p-ideals of a restricted Lie triple system. Finally, we study how a quasi-toral restricted Lie triple system T with zero center and of minimal dimension should be.

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43

Ludwig, Heinz, Werner Linkesch, Hedwig Kasparu, Otto Krieger, Ivan Spicka, Gunther Gastl, Richard Greil, et al. "Prospective, Randomized Comparison between Double Transplantation (T) with Melphalan (200 mg/m2) and Triple T with Intermediate Dose Melphalan (100 mg/m2) in Patients with Multiple Myeloma (An Interim Analysis)." Blood 108, no. 11 (November 16, 2006): 3083. http://dx.doi.org/10.1182/blood.v108.11.3083.3083.

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Abstract In this study we compare the efficacy and toxicity of double T with M 200 with triple T using M 100 in newly diagnosed pts with MM. 175 pts have as yet been enrolled and 135 have been randomized after VAD induction treatment and stem cell collection to either tandem or triple transplantation. Reasons for non-randomization were too early for T (n=22), PD after induction (n=5), early death (n=3), toxicity (n=3), pt. refusal (n=3), and others (n=4). Median age of the 135 pts randomized was 59 years (range: 27–70 years). Stage I: 8%, stage II: 17%, stage III: 75%, Paraprotein Isotypes: IgG: 55%, IgA: 25%, IgD: 2%, IgM: 1%, Light chain: 17%. Induction treatment: 3 cycles of VAD; stem cell priming: IEV (ifosfamide (2g/m2)-etoposide (150mg/m2), d1–3; epirubicin (50mg/m2), d1) and G-CSF (5mg/kg) from d4. Conditioning regimen: M 200 mg/m2 or M 100 mg/m2 plus G-CSF; day 5 until WBC >2000/ml. Pts with ≥ SD after T were subsequently randomized to interferon 3MU, TIW (Schering Plough) plus prednisone (25mg, po., TIW), or interferon alone. QoL was assessed with the EORTC QLQ C30 instrument. Chi2 test for trend was used for comparison of response and survival endpoints were estimated by the Kaplan-Meier product limit method. Response rates after VAD were CR: 11%, PR: 65%, SD: 22% and PD: 2%. Median time from start of VAD to start of T was 137 in the double and 139 days in the triple T arm. Response rates did not differ between pts treated with double or triple T (CR: 47% vs. 43%, PR: 47% vs. 47%, SD 2% vs. 6%, PD: 4% vs. 4%, p=0.60, respectively). Median PFS for both groups combined was 36 mos, but showed a tendency for shorter PFS in pts on triple T (23 mos. vs. 37.5 mos; HR 1.26, 95% CI: 0.72–2.23, p=0.21). Median of OS has not been reached yet, but did not differ between both groups. Hematological toxicity was similar in both groups. There was a tendency for more grade 2–4 mucositis and for grade 3–4 vomiting, nausea, and fatigue in the double T group. Global QoL (questions 29 and 30) was comparable between both groups, before (5 (2.5–6.5) vs. 5 (4.5–6)) and after double (5.8 (3–8.5) or triple T (6 (2.5–7)). In conclusion, triple T with intermediate dose M resulted in similar response rates, slightly shorter PFS but similar OS and was associated with less mucositis and slightly less vomiting, nausea and fatigue. Progression-free survival by randomization group Progression-free survival by randomization group

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Josuat-Vergès, Matthieu, and Jang Soo Kim. "Touchard–Riordan formulas, T-fractions, and Jacobi’s triple product identity." Ramanujan Journal 30, no. 3 (September 13, 2012): 341–78. http://dx.doi.org/10.1007/s11139-012-9403-9.

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45

Köhler, R., M. Kasper, T. M. Herbst, T. Ratzka, and G. H. M. Bertrang. "Orbits in the T Tauri triple system observed with SPHERE." Astronomy & Astrophysics 587 (February 12, 2016): A35. http://dx.doi.org/10.1051/0004-6361/201527125.

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46

Böhm, Dieter, Frank Heinemann, Dongqi Hu, Susanne Kummer, and Ulrich Zenneck. "A Specific π-Ligand Transfer Reaction via Triple-Decker Sandwich Complex Intermediates." Collection of Czechoslovak Chemical Communications 62, no. 2 (1997): 309–17. http://dx.doi.org/10.1135/cccc19970309.

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Photochemically generated cationic cyclopentadienyl iron fragments [FeCp]+ allow a specific stacking reaction of [(t-Bu3C3P2)Fe(t-Bu2C2P3)]. This results in the transient formation of an unstable cationic Fe-Fe triple-decker sandwich complex which decomposes by deliberating the neutral sandwich complex [CpFe(t-Bu2C2P3)], and is stacked again by a second [FeCp]+-unit, yielding the moderately stable cationic triple-decker sandwich complex [CpFe(t-Bu2C2P3)FeCp]+ with a central mi-eta5:eta5-triphospholyl ligand. Air exposure or storage of solutions at room temperature leads to a destacking and the neutral triphosphaferrocene derivative [CpFe(t-Bu2C2P3)] is formed again almost quantitatively in respect to the pentaphospha-ferrocene educt.

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47

Mehra, Maneesha, Martin Vogel, Satish Valluri, Sandhya Nair, Jordan Schecter, Sundar Jagannath, Katja Weisel, and Saad Zafar Usmani. "Patient characteristics and treatment patterns in relapsed/refractory multiple myeloma patients after exposure to a proteasome inhibitor, an immunomodulatory agent and daratumumab." Journal of Clinical Oncology 38, no. 15_suppl (May 20, 2020): e20540-e20540. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e20540.

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e20540 Background: Many novel agents, such as a Chimeric Antigen Receptor T-Cell (CAR-T) therapy, are under investigation for the treatment of relapsed/refractory multiple myeloma (RRMM) patients (pts) who have been exposed to a proteasome inhibitor (PI), immunomodulatory drug (IMiD), and daratumumab (triple-exposed). However, limited data are available on treatment patterns in these pts. Here, we aim to study characteristics and treatment patterns after triple-exposure in RRMM pts. Methods: Data from triple-exposed RRMM pts from the Flatiron MM core registry (Jan 1, 2011 - Oct 2019) who received ≥3 prior lines of therapy (LOT) were used for the analyses. Descriptive statistics for pt characteristics and treatment patterns were assessed at end of triple exposure LOT (time T0) and after triple exposure by LOT. Results: Of the 10,011 MM pts in the Flatiron registry, 1,029 were triple-exposed; of these, 362 had a LOT after triple-exposure. Median age at T0 was 68 years and time to triple-exposure was 3.5 years from index MM diagnosis (Table). 52% were male, 81% (of 250 with available ECOG data) had ECOG status < 2, and 54% had a stem cell transplant. In 96% of pts, daratumumab was part of the triple-exposure regimen. Median follow-up from triple-exposure (LOT end date) was 7.4 months. 49% and 23% of pts had ≥2 LOTs and ≥3 LOTs after triple-exposure. Pomalidomide-, carfilzomib-, or daratumumab-containing regimens accounted for 71% and 49% of all LOT1-post-triple and LOT3 post-triple treatments, respectively; non-novel treatments accounted for 18% and 30% of LOT1 post-triple and LOT3 post-triple treatments. Conclusions: Triple-exposed RRMM pts accounted for approximately 10% of the population in the Flatiron MM core registry. Triple-exposed RRMM pts progress to multiple LOT in which they continue to be treated with PIs, IMiDs, and daratumumab; therefore, there is a need for new treatments with novel mechanisms of action for this pt population. [Table: see text]

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48

Radigan, Jacqueline, Ray Jayawardhana, David Lafrenière, Trent J. Dupuy, Michael C. Liu, and Alexander Scholz. "DISCOVERY OF A VISUAL T-DWARF TRIPLE SYSTEM AND BINARITY AT THE L/T TRANSITION." Astrophysical Journal 778, no. 1 (October 31, 2013): 36. http://dx.doi.org/10.1088/0004-637x/778/1/36.

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Jagtap, SunilVitthalrao. "Evaluation of CD4+ T-cells and CD8+ T-cells in triple-negative invasive breast cancer." Indian Journal of Pathology and Microbiology 61, no. 4 (2018): 477. http://dx.doi.org/10.4103/ijpm.ijpm_201_18.

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50

Taghavi, Ali, Mehran Razeghi, Mojtaba Nouri, Vahid Darvish, and C. Li. "Additivity of maps preserving triple product on *-ring." Boletim da Sociedade Paranaense de Matemática 39, no. 5 (January 1, 2021): 25–41. http://dx.doi.org/10.5269/bspm.40370.

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Let A and B be two prime -rings. Let : A ! B be a bijective and satises (A P P) = (A) (P) (P); for all A 2 A and P 2 fI; P1; I 􀀀 P1g where P1 is a projection in A. The operation between two arbitrary elements S and T in A is dened as S T = ST +TS for 2 f􀀀1; 1g. Then, if (I) is projection, we show that is additive.

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