Relevant bibliographies by topics / TRIM protein

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'TRIM protein'

Author: Grafiati
Published: 1 April 2023
Last updated: 31 July 2025

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Journal articles on the topic "TRIM protein"

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Yap, Melvyn W., Mark P. Dodding, and Jonathan P. Stoye. "Trim-Cyclophilin A Fusion Proteins Can Restrict Human Immunodeficiency Virus Type 1 Infection at Two Distinct Phases in the Viral Life Cycle." Journal of Virology 80, no. 8 (2006): 4061–67. http://dx.doi.org/10.1128/jvi.80.8.4061-4067.2006.

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ABSTRACT The Trim5α protein from several primates restricts retroviruses in a capsid (CA)-dependent manner. In owl monkeys, the B30.2 domain of Trim5 has been replaced by cyclophilin A (CypA) following a retrotransposition. Restriction of human immunodeficiency virus type 1 (HIV-1) by the resulting Trim5-CypA fusion protein depends on CA binding to CypA, suggesting both that the B30.2 domain might be involved in CA binding and that the tripartite RING motif, B-BOX, and coiled coil (RBCC) motif domain can function independently of the B30.2 domain in restriction. To investigate the potential of
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Xiao, Maolin, Jianjun Li, Qingyuan Liu, Xiangbiao He, Zongke Yang, and Delin Wang. "Expression and Role of TRIM2 in Human Diseases." BioMed Research International 2022 (August 23, 2022): 1–14. http://dx.doi.org/10.1155/2022/9430509.

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Tripartite motif (TRIM) protein family proteins contain more than 80 members in humans, and most of these proteins exhibit E3 ubiquitin ligase activity mediated through a RING finger domain. Their biological functions are very complex, and they perform diverse functions in cell evolution processes, such as intracellular signaling, development, apoptosis, protein quality control, innate immunity, autophagy, and carcinogenesis. Tripartite motif-containing protein 2 (TRIM2), a member of the TRIM superfamily, is an 81 kDa multidomain protein, also known as CMT2R or RNF86, located at 4q31.3. TRIM2
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Pauletto, Eleonora, Nils Eickhoff, Nuno Padrão, Christine Blattner, and Wilbert Zwart. "TRIMming Down Hormone-Driven Cancers: The Biological Impact of TRIM Proteins on Tumor Development, Progression and Prognostication." Cells 10, no. 6 (2021): 1517. http://dx.doi.org/10.3390/cells10061517.

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The tripartite motif (TRIM) protein family is attracting increasing interest in oncology. As a protein family based on structure rather than function, a plethora of biological activities are described for TRIM proteins, which are implicated in multiple diseases including cancer. With hormone-driven cancers being among the leading causes of cancer-related death, TRIM proteins have been described to portrait tumor suppressive or oncogenic activities in these tumor types. This review describes the biological impact of TRIM proteins in relation to hormone receptor biology, as well as hormone-indep
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Hage, Adam, Mikhaila Janes, and Sonja M. Best. "A No-Brainer! The Therapeutic Potential of TRIM Proteins in Viral and Central Nervous System Diseases." Viruses 17, no. 4 (2025): 562. https://doi.org/10.3390/v17040562.

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Tripartite motif (TRIM) proteins comprise an important class of E3 ubiquitin ligases that regulate numerous biological processes including protein expression, cellular signaling pathways, and innate immunity. This ubiquitous participation in fundamental aspects of biology has made TRIM proteins a focus of study in many fields and has illuminated the negative impact they exert when functioning improperly. Disruption of TRIM function has been linked to the success of various pathogens and separately to the occurrence and development of several neurodegenerative diseases, making TRIM proteins an
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Chiang, De Chen, and Beow Keat Yap. "TRIM25, TRIM28 and TRIM59 and Their Protein Partners in Cancer Signaling Crosstalk: Potential Novel Therapeutic Targets for Cancer." Current Issues in Molecular Biology 46, no. 10 (2024): 10745–61. http://dx.doi.org/10.3390/cimb46100638.

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Aberrant expression of TRIM proteins has been correlated with poor prognosis and metastasis in many cancers, with many TRIM proteins acting as key oncogenic factors. TRIM proteins are actively involved in many cancer signaling pathways, such as p53, Akt, NF-κB, MAPK, TGFβ, JAK/STAT, AMPK and Wnt/β-catenin. Therefore, this review attempts to summarize how three of the most studied TRIMs in recent years (i.e., TRIM25, TRIM28 and TRIM59) are involved directly and indirectly in the crosstalk between the signaling pathways. A brief overview of the key signaling pathways involved and their general c
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Wu, Wangxi, Jinyu Yang, Tian Yu, Zhuoling Zou, and Xuan Huang. "The Role and Mechanism of TRIM Proteins in Gastric Cancer." Cells 13, no. 24 (2024): 2107. https://doi.org/10.3390/cells13242107.

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Tripartite motif (TRIM) family proteins, distinguished by their N-terminal region that includes a Really Interesting New Gene (RING) domain with E3 ligase activity, two B-box domains, and a coiled-coil region, have been recognized as significant contributors in carcinogenesis, primarily via the ubiquitin–proteasome system (UPS) for degrading proteins. Mechanistically, these proteins modulate a variety of signaling pathways, including Wnt/β-catenin, PI3K/AKT, and TGF-β/Smad, contributing to cellular regulation, and also impact cellular activities through non-signaling mechanisms, including modu
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Bruyns, Eddy, Anne Marie-Cardine, Henning Kirchgessner та ін. "T Cell Receptor (TCR) Interacting Molecule (TRIM), A Novel Disulfide-linked Dimer Associated with the TCR–CD3–ζ Complex, Recruits Intracellular Signaling Proteins to the Plasma Membrane". Journal of Experimental Medicine 188, № 3 (1998): 561–75. http://dx.doi.org/10.1084/jem.188.3.561.

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The molecular mechanisms regulating recruitment of intracellular signaling proteins like growth factor receptor–bound protein 2 (Grb2), phospholipase Cγ1, or phosphatidylinositol 3-kinase (PI3-kinase) to the plasma membrane after stimulation of the T cell receptor (TCR)– CD3–ζ complex are not very well understood. We describe here purification, tandem mass spectrometry sequencing, molecular cloning, and biochemical characterization of a novel transmembrane adaptor protein which associates and comodulates with the TCR–CD3–ζ complex in human T lymphocytes and T cell lines. This protein was terme
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Liu, Yilin. "The Role of TRIM Proteins in Antiviral Defense." Highlights in Science, Engineering and Technology 74 (December 29, 2023): 1655–60. http://dx.doi.org/10.54097/a127xa83.

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The Tripartite motif (TRIM) protein family is classified among a cohort of E3 ubiquitin ligase families. A large percentage of TRIM proteins are E3 ubiquitin ligase active and take part in a number of cellular functions. By adding ubiquitin molecules to target proteins via a variety of techniques, it can change those proteins. The important role of the TRIM protein in controlling pattern recognition receptor signaling pathways and the defense mechanisms of mammals against viruses, with a focus on protecting the host from viral infections, has been clarified by recent study. In addition to trig
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Azuma, Kotaro, and Satoshi Inoue. "Efp/TRIM25 and Its Related Protein, TRIM47, in Hormone-Dependent Cancers." Cells 11, no. 15 (2022): 2464. http://dx.doi.org/10.3390/cells11152464.

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Increasing attention has been paid to the biological roles of tripartite motif-containing (TRIM) family proteins, which typically function as E3 ubiquitin ligases. Estrogen-responsive finger protein (Efp), a member of the TRIM family proteins, also known as TRIM25, was originally identified as a protein induced by estrogen and plays critical roles in promoting endocrine-related cancers, including breast cancer, endometrial cancer, and prostate cancer. The pathophysiological importance of Efp made us interested in the roles of other TRIM family proteins that share a similar structure with Efp.
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Nenasheva, V. V., E. A. Stepanenko, and V. Z. Tarantul. "Multi-Directional Mechanisms of Action of <i>TRIM</i> Family Genes in the Response of the Innate Immune System to Bacterial Infections (Review)." Biohimiâ 89, no. 7 (2024): 1229–47. https://doi.org/10.31857/s0320972524070076.

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Multigene TRIM family is an important component of the innate immune system. For a long time, it was believed that the main function of the genes of this family is the antiviral defense of the host organism. The question of their participation in the response of the immune system to bacterial invasion remained less studied. This review represents the first comprehensive analysis of the mechanisms of action of TRIM family genes in response to bacterial infections, which expands the existing understanding of the role of TRIM in the functioning of the innate immune system. Upon the infection with
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Dissertations / Theses on the topic "TRIM protein"

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Najmabadi, Sepideh. "Drosophila model of myosin myopathy rescued by overexpression of a TRIM-protein family member." Thesis, Högskolan i Skövde, Institutionen för hälsa och lärande, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-17919.

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Laing distal myopathy is inherited in an autosomal dominant manner usually before the age of five that initially involves the dorsiflexion in the ankles’ and in big toes to the finger extensors. Weakness of the flexor muscles in the neck is seen in most affected individuals and mild facial weakness is also often present. Hypertrophic or dilated cardiomyopathy, starting at birth to respectively second or third decade of life, is the symptom in the affected humans.This study performed on Drosophila melanogaster, has evaluated whether feeding MuRF1 enzyme (which has a similar role as ABBA enzyme)
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Zhang, Xuzhe. "Eutherian-specific gene TRIML2 attenuates inflammation in the evolution of placentation." University of Cincinnati / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1573576401238203.

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MASCARO, MARTINA. "Ruolo di TRIM18, gene che causa la sindrome di Opitz, nel controllo della ciliogenesi attraverso l'autofagia." Doctoral thesis, Università degli Studi di Trieste, 2021. http://hdl.handle.net/11368/2996095.

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TRIM18/MID1 è una E3-Ubiquitina ligasi appartenente alla famiglia di proteine TRIM che si localizza sui microtubuli. Le mutazioni con perdita di funzione nel gene MID1 sono state associate alla forma legata all'X della sindrome di Opitz, una malattia genetica caratterizzata da difetti nello sviluppo della linea mediana ventrale. All'interno della cellula, MID1 esiste come un complesso macromolecolare microtubulare, costituito da diversi interattori non tutti ancora identificati. Tra questi, α4 è una delle subunità regolatorie della proteina fosfatasi 2A (PP2A). È stato riportato che MID1 riduc
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Demange, Antonin. "Protéines à motif tripartite (TRIM) chez le porc (Sus scrofa) et réplication du rétrovirus endogène porcin." Phd thesis, Université Rennes 1, 2013. http://tel.archives-ouvertes.fr/tel-00992386.

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Les études des interactions entre cellules hôtes et rétrovirus ont conduit à définir le concept de restriction virale dont les facteurs constituent une part de l'immunité innée des cellules hôtes. Ces facteurs contribuent au contrôle des rétrovirus endogènes (ERV) dont l'émergence peut être associée à certaines pathologies telles que des leucémies ou des immunodéficiences. Chez le porc, certains ERV (PERV) sont réplicatifs, pourtant aucune pathologie ne leur a, à ce jour, été associée. Les mécanismes de restriction virale impliqués dans ce phénomène ont fait l'objet de nombreuses études. Elles
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Fraser, S. J. "Characterising retroviral restriction by TRIM proteins." Thesis, University College London (University of London), 2016. http://discovery.ucl.ac.uk/1532045/.

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Tripartite motif (TRIM) proteins are numerous in the human proteome, and a number of these molecules are known to restrict retroviral replication. TRIM5α (T5α) is one such factor. It targets the viral capsid and imposes a block to infection between entry and reverse transcription. Capsid recognition is mediated by the C-terminal B30.2 domain, which contains surface-exposed loops of high amino acid variability. Restriction is then effected via proteasome recruitment and the induction of innate immune cascades. Although T5α is well-characterised in this respect, other factors – such as the highl
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Fekete, Richard Alfred. "Characterizing the protein and DNA interactions of the F plasmid DNA binding protein, TraM." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/NQ60291.pdf.

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Marafie, Sulaiman. "TRIM7, a novel binding protein of the mTORC2 component Sin1." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/trim7-a-novel-binding-protein-of-the-mtorc2-component-sin1(c344b542-0706-4ec0-be06-ce6683cee52e).html.

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TRIM7 is a member of the TRIM (tripartite motif-containing) protein superfamily. This family has been implicated in many disorders such as genetic diseases, neurological diseases, and cancers. Little is known about the function of TRIM7 except that it interacts with glycogenin and may regulate glycogen biosynthesis. Recently, a yeast two-hybrid protein-protein interaction screen revealed the binding of TRIM7 to Sin1, a protein found in a complex with the mammalian target of rapamycin (mTOR) protein kinase. mTOR can form two complexes, mTORC1 and mTORC2, which are important for cell growth, dif
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Simpson, Shmona. "Genetic, structural, and functional exploration of the restrictive capacity of TRIM proteins against immunodeficiency viruses." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:1af588ba-603a-4f39-9443-bb1a95d983f5.

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HIV-2 differs from HIV-1 in that many infected people experience normal survival, whilst only 20&percnt; progress rapidly to AIDS. Understanding mechanisms of delayed HIV-2 disease progression could provide new insights into HIV control. The Caio Community Cohort was established in Guinea-Bissau in the setting of high HIV-2 prevalence. This thesis investigates the role of polymorphic host restriction factors of the TRIM family in HIV-2 outcome. TRIM proteins are a family of E3 ubiquitin-ligases, where closely-related TRIM5&alpha; and TRIM22 are thought to inhibit HIV-1 transcription, uncoating
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Liu, Sunbin. "Investigation of protein-protein interactions within the human spliceosomal U4/U6.U5 tri-snRNP particle." Doctoral thesis, [S.l.] : [s.n.], 2005. http://webdoc.sub.gwdg.de/diss/2005/liu/liu.pdf.

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Xin, Gang. "The role of TREM proteins in lung homeostasis and inflammation." Thesis, Imperial College London, 2011. http://hdl.handle.net/10044/1/9058.

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The family of Triggering Receptors Expressed on Myeloid Cells (TREM) contain novel activating receptors of the Ig super-family that are expressed on myeloid cells. TREM-1 is a transmembrane glycoprotein expressed on blood neutrophils and a subset of monocytes, but not on lymphocytes or other cell types and is upregulated by bacterial and fungal products. TREM-1 signaling potentiates the outcome of Toll-like Receptor (TLR) signaling. Blockade of TREM-1 prevents experimentally induced septic shock. In addition to the membrane-bound form, a soluble TREM-1 molecule (sTREM-1) exists that regulates
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Books on the topic "TRIM protein"

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Meroni, Germana, ed. TRIM/RBCC Proteins. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-5398-7.

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Meroni, Germana. TRIM/RBCC proteins. Springer Science+Business Media, 2012.

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Meroni, Germana. TRIM/RBCC Proteins. Springer London, Limited, 2013.

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Meroni, Germana. TRIM/RBCC Proteins. Springer, 2016.

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Hetz, Claudio, ed. Protein Misfolding Disorders: A Trip into the ER. BENTHAM SCIENCE PUBLISHERS, 2012. http://dx.doi.org/10.2174/97816080501301090101.

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Stefano, Vittorio De. Origins of specificity in protein modification: Reaction patterns of tris-trimesates with human hemoglobin A, water, and n-propylamine. Dept of Chemistry, U of Toronto, 1999.

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Nikravan, Sara, and Frederick Mihm. Pathophysiology and management of functional endocrine tumours in the critically ill. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0264.

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Thyroid hormones act on most tissues via nuclear T3 receptors. Thyroid hormones stimulate oxygen consumption and heat production, influence cell growth and maturation (central nervous system, bone), and modulate metabolism (carbohydrates, lipids, proteins, drugs). Treatment for presumed thyroid disease frequently has to be initiated before the results of diagnostic tests are available. Treatment of hyperthyroidism should result in the reduction of serum thyroid hormone levels and their action on peripheral tissues with concurrent treatment of the precipitating event. In severe hypothyroidism t
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Andersson, Jenny. Bridging the Iron Curtain. Futurology as Dissidence and Control. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198814337.003.0007.

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East European futurists were part of the transnational networks of futures research. The Ford Foundation sent Daniel Bell on a study trip in 1960 during which he made contact with some of the key milieus of revisionist Marxist thought: the Polska 2000 group led by Andrej Sicinski as well as the group of sociologists under the leadership of Radovan Richta in Prague. After 1968, futurologists helped introduce forms of management and computer science into the planning systems of the socialist economies under the banner of prognostika. The chapter examines the way that East European futurists used
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Editors of Creative Publishing international. Black and Decker the Complete Guide to Roofing Siding and Trim: Updated 2nd Edition, Protect and Beautify the Exterior of Your Home. Quarto Publishing Group USA, 2008.

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Glatz, Phil, and Michael Bourke. Beak Trimming Handbook for Egg Producers. CSIRO Publishing, 2006. http://dx.doi.org/10.1071/9780643093539.

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The Beak Trimming Handbook for Egg Producers is a straightforward, practical guide to beak trimming of egg-laying hens to minimise cannibalism. It provides comprehensive information on why birds peck and how pecking can lead to problems like cannibalism; the methods available to beak trim birds; why a particular method should be chosen; and at what age birds may be trimmed.&#x0D; The book addresses quality control of beak trimming, enabling egg producers to be confident that equipment is properly set up, that birds are handled and trimmed according to best practice and farm biosecurity is main
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Book chapters on the topic "TRIM protein"

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Nisole, Sébastien. "TRIM Protein Family and Viral Restriction." In Encyclopedia of AIDS. Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4614-9610-6_383-1.

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Nisole, Sébastien. "TRIM Protein Family and Viral Restriction." In Encyclopedia of AIDS. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-7101-5_383.

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Fletcher, Adam J., and Greg J. Towers. "Inhibition of Retroviral Replication by Members of the TRIM Protein Family." In Current Topics in Microbiology and Immunology. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-37765-5_2.

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Petrera, Francesca, and Germana Meroni. "TRIM Proteins in Development." In Advances in Experimental Medicine and Biology. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-5398-7_10.

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Cambiaghi, Valeria, Virginia Giuliani, Sara Lombardi, Cristiano Marinelli, Francesca Toffalorio, and Pier Giuseppe Pelicci. "TRIM Proteins in Cancer." In Advances in Experimental Medicine and Biology. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-5398-7_6.

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Fisher, Barbara. "5. The Heart of a Maid." In Trix. Open Book Publishers, 2024. http://dx.doi.org/10.11647/obp.0377.05.

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Immediately after a brief honeymoon, Jack was sent to Burma to continue his work on the Great Survey of India. Trix stayed behind in Lahore, where she began work on a novel featuring an unfeeling heroine struggling through the early years of a mis-matched and bitterly unhappy marriage. In January of 1890, after less than six months in Burma, Jack became sick and was granted home leave. Having to remove promptly to England, Trix hastily and harshly concluded her novel. Just two years into her marriage, Trix’s novel, The Heart of a Maid, appeared under the pen name Beatrice Grange. The pen name
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Ikeda, Kazuhiro, and Satoshi Inoue. "Trim Proteins as Ring Finger E3 Ubiquitin Ligases." In Advances in Experimental Medicine and Biology. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-5398-7_3.

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Yap, Melvyn W., and Jonathan P. Stoye. "TRIM Proteins and the Innate Immune Response to Viruses." In Advances in Experimental Medicine and Biology. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-5398-7_7.

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Shen, Koning, and Judith Frydman. "The interplay between the chaperonin TRiC and N-terminal region of Huntingtin mediates Huntington’s Disease aggregation and pathogenesis." In Protein Quality Control in Neurodegenerative Diseases. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-27928-7_10.

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Wang, Hua, Heng Huang, Chris Ding, and Feiping Nie. "Predicting Protein-Protein Interactions from Multimodal Biological Data Sources via Nonnegative Matrix Tri-Factorization." In Lecture Notes in Computer Science. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-29627-7_33.

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Conference papers on the topic "TRIM protein"

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Wang, Qiwei, Tao Chen, Tawfiq Al-Shafai, and Sultan Alsubaie. "Calcium Carbonate Scale Deposition and Inhibition: Effects of Corrosion Inhibitors." In CORROSION 2021. AMPP, 2021. https://doi.org/10.5006/c2021-16736.

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Abstract Scale and corrosion inhibitors are often applied simultaneously in order to prevent inorganic deposition and protect system integrity of oilfield facilities. The compatibility between these chemicals is a major concern during chemical selection. Corrosion inhibitor compounds may form complex with scale inhibitor molecules and interfere with the interactions of scale inhibitor and scaling crystal, and consequently, affect the scale inhibitor performance. Understanding their interplay is of importance for the development of cost effective treatment programs. In this work, the impacts of
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Dyer, R. Brian, and Timothy P. Causgrove. "Ultrafast Protein Relaxation: Time-Resolved Infrared Studies of Protein Dynamics Triggered by CO Photodissociation from CO Myoglobin." In International Conference on Ultrafast Phenomena. Optica Publishing Group, 1994. http://dx.doi.org/10.1364/up.1994.tub.4.

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A critical feature of the biological function of heme proteins is the direct coupling of protein motion to the process of binding exogenous ligands to the heme. In carbonmonoxymyoglobin (MbCO), a substantial, specific conformational relaxation is associated with the transition from the ligated to the unligated form of the protein. The analogous tertiary structural changes of the monomer heme subunits of hemoglobin ultimately lead to the R→T quaternary structural transition, the allosteric control mechanism of O2 binding efficiency [1]. We have studied these processes on the earliest timescales
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Saundry, R. H., S. Khumprayoon, and G. F. Savidge. "THE IDENTIFICATION OF A NOVEL FACTOR X ACTIVATOR ACTIVITY IN Mg2+ - ANTICOAGULATED PLASMA." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643293.

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Mg2+ anticoagulated PPP (20mM MgCl2) was applied at RT to a Zn2+ immobilised biscarboxymethylamino Sepharose 4B column and eluted with 20mM Tris, 20mM MgCl2, 2.5mM CaCl2 0.15M NaCl buffer pH 7.4. Following collection of the wash-through fractions, bound proteins were developed through application of linear (0 to 35mM) imidazole gradients.All fractions were screened for F.II, V, IX, X, vWF:Ag, Protein C, Fg, Fn and 2-macroglobulin by ELISA, VIII:Ag by IRMA, and VIII:C by both 1-stage and 2-stage bioassay methods. VIIIrAg (60-90% yield), vWF:Ag (100%), VIII:C 1-stage activity (35%), Fn (&gt; 60%
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Bossard, Carine, Dinorah Friedmann-Morvinski, Conrado Soria, et al. "Abstract 4061: TRIM-NHL proteins: New potential targets for cancer therapy." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-4061.

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Yonashiro, Kan, and Kouichi Hirata. "Trim Distance between Positions in Nucleotide Sequences for Structural Proteins of SARS-CoV-2." In 2021 10th International Congress on Advanced Applied Informatics (IIAI-AAI). IEEE, 2021. http://dx.doi.org/10.1109/iiai-aai53430.2021.00006.

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Owen, B. A., and W. G. Owen. "ASSOCIATION OF HEPARIN AND FACTOR Xa: INFLUENCE ON THE RATE OF INHIBITION OF FACTOR Xa BY ANTITHROMBIN III-HEPARIN." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643837.

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Association of heparin non-covalently with bovine factor Xa was analyzed by Superose-12 gel chromatography. In 0.05 M NaCl, 0.02 M Tris, pH 7.5, DEGR-Xa (factor Xa inactivated by dans-Glu-Gly-Arg-CH2Cl) was eluted as a single, sharp peak at Ve/Vt=0-65 (elution volume/internal volume). Mixtures of heparin and DEGR-Xa were eluted as two partially resolved peaks of protein at Ve/Vt=0.59 and 0.65. The fraction of DEGFUXa in the leading peak was directly proportional to [heparin], and at 100 yM heparin the leading peak contained more than half the total protein. When 0.02 M HEPES was substituted fo
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Kim, Joongsoo, Rakesh Kumar, and Jung-Mo Ahn. "Tris-Benzamide Analogs for Inhibiting Bcl-2 Proteins in Prostate Cancer." In The 24th American Peptide Symposium. Prompt Scientific Publishing, 2015. http://dx.doi.org/10.17952/24aps.2015.170.

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Mager, J., A. Burgess, R. Pavan, and J. Orzechowski. "Thick Aluminum Coatings Using Axial Plasma Spray for Proton Beam Collimators." In ITSC2004, edited by Basil R. Marple and Christian Moreau. ASM International, 2004. http://dx.doi.org/10.31399/asm.cp.itsc2004p0076.

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Abstract Aluminum coatings minimum 1.8 mm thick are applied to water-cooled proton beam collimators used in the manufacture of medical isotopes on the TRIUMF TR30 cyclotrons in Vancouver, British Columbia, Canada. The sprayed surface of the collimators is made from silver. These collimators are used to trim the proton beam so that only a designated area on the isotope production target is irradiated with protons. Aluminum is used because its activation products at the energies used have short half-lives, thus minimizing the amount of collateral radioactivity produced. The aluminum is sprayed u
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Pokidova, Olesya Viktorovna, Nina Sergeevna Emel’yanova, Alexander Vasilievich Kulikov, Alexander Ivanovich Kotelnikov, and Natalia Alekseevna Sanina. "STUDY OF THE TRANSFORMATION OF NITROSYL IRON COMPLEX WITH N-ETHYLTHIOUREA LIGANDS IN MODEL BIOLOGICAL SYSTEMS." In NEW TECHNOLOGIES IN MEDICINE, BIOLOGY, PHARMACOLOGY AND ECOLOGY. Institute of information technology, 2021. http://dx.doi.org/10.47501/978-5-6044060-1-4.52.

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The process of transformation of a mononuclear cationic complex with N-ethylthiourea ligands in Tris-HCl buffer, as well as in a reaction mixture with reduced glutathione and bovine serum albumin, has been studied. It was found that in the presence of glutathione, the complex dimer-izes, while its initial ligands are replaced by glutathione. In the presence of albumin, the decay product of the complex is coordinated with amino acid residues (Cys34 and His39) to form a protein-bound complex.
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Siess, W., and E. G. Lapetina. "SYNERGISM OF Gi-DISSOCIATION AND PROTEIN KINASE C STIMULATION IN PLATELET ACTIVATION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644511.

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Epinephrine or UK 14304 (a specific (α2-adrenoceptor agonist) synergizes with phorbol esters (phorbol 12,13-dibutyrate, PdBu) or bioactive diacylglycerols (sn-1,2-dioctanoylglycerol, DiC8) to induce aggregation and ATP-secretion of platelets. The effect on aggregation is more pronounced than on secretion, and it is observed in aspirinized platelet-rich plasma or suspensions of washed platelets containing ADP-scavengers. No prior shape change is found. In the presence of epinephrine, DiCg induces reversible aggregation and PdBu evokes irreversible aggregation that correlates with the effects, o
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Reports on the topic "TRIM protein"

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Shchurenko, Anastasia. PATENT PROTECTION OF MODERN SMART TECHNOLOGIES. Intellectual Archive, 2024. http://dx.doi.org/10.32370/iaj.3045.

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FORMING THE BASIS OF A PATENT APPLICATION TO PROTECT THE TECHNOLOGY FOR PRODUCING SMART COMPOSITE CONFECTIONERY PRODUCTS AND HOMOGENIZED BEVERAGES. Using TRIZ and ARIZ analytical tools when preparing a provisional patent application to the US Patent Office. The specialization of the technical solution underlying the application is the production technology of composite confectionery products and smart combined food drinks (drinking emulsions) with a high degree of homogenization.
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Droby, Samir, Michael Wisniewski, Ron Porat, and Dumitru Macarisin. Role of Reactive Oxygen Species (ROS) in Tritrophic Interactions in Postharvest Biocontrol Systems. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7594390.bard.

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To elucidate the role of ROS in the tri-trophic interactions in postharvest biocontrol systems a detailed molecular and biochemical investigation was undertaken. The application of the yeast biocontrol agent Metschnikowia fructicola, microarray analysis was performed on grapefruit surface wounds using an Affymetrix Citrus GeneChip. the data indicated that 1007 putative unigenes showed significant expression changes following wounding and yeast application relative to wounded controls. The expression of the genes encoding Respiratory burst oxidase (Rbo), mitogen-activated protein kinase (MAPK)
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ชวนชื่น, รุ่งทิพย์, พรเพ็ญ พัฒนโสภณ та ศุภชัย เนื้อนวลสุวรรณ. การเฝ้าระวังการดื้อต่อยาฆ่าเชื้อและยาปฏิชีวนะของ Salmonella spp. และ Escherichia coli ในสายพันธุ์ที่แยกได้ในประเทศไทย : รายงานการวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 2006. https://doi.org/10.58837/chula.res.2006.87.

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แยก Salmonella enterica จำนวน 257 isolates และ Escherichia coli จำนวน 60 isolates จากตัวอย่างที่ได้จาก ไก่ สุกรและสิ่งแวดล้อมในฟาร์ม ทำการหาค่า minimal inhibitory concentration (MIC) ต่อยาปฏิชีวนะและยาฆ่าเชื้อ ได้แก่ ampicillin (AMP) chloramphenicol (CHP) ciprofloxacin (CIP) erythromycin (ERY) gentamycin (GEN) tetracycline (TET) trmethoprim (TRI) benzalkonium chloride (BKC) chlorhexidine (CHX), copper sulfate (CuSO4) และ zinc chloride (ZnCl2) พบว่า salmonella 162 isolates (63.04%) และ E. coli 50 isolates (83.33%) ดื้อต่อยาปฏิชีวนะอย่างน้อยหนึ่งชนิด ค่า MIC ต่อ BKC, CHX, CUSO4 และ ZnCl2 เกาะกัน
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