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1

Arora, Rashmi, and Naresh S. Gill. "Evaluation of Anti-inflammatory Activity of Trichosanthes dioica Roxb. Seeds." International Journal of Pharmaceutical Sciences and Drug Research 13, no. 03 (March 3, 2020): 263–67. http://dx.doi.org/10.25004/ijpsdr.2021.130304.

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Inflammation a complex disease associated with various symptoms. These symptoms can be managed with non-steroidal and steroidal anti-inflammatory drugs, which lead to severe side effects on long-term use. Natural products are used as an alternative source of the discovery of new entities to be used as compounds anti-inflammatory compounds to overcome this problem. Trichosanthes diocia (T. diocia) belongs to Cucurbitaceae family. T. dioica, a dioecious perennial herbaceous vegetable, is a rich source of vitamin C and minerals. In addition to fruits, leaves and tender shoots have been used in the indigenous system of medicine. The objective of the present study was to evaluate the anti-inflammatory activity of methanolic extract of T. dioica seeds for scientific validation of the folklore claim of the plant The extract was evaluated at three different concentrations of 100, 200, and 400 mg/kg, p.o. Significant dose-dependent anti-inflammatory activity was observed, comparable with that of the standard drug indomethacin at a dose of 10 mg/kg.
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2

Sahu, Ipsita, Akshya Mishra, Debashish Gardia, and Aishwarya Khamari. "Microscopic analysis of Trichosanthes dioica." Journal of Medicinal Plants Studies 10, no. 5 (September 1, 2022): 51–53. http://dx.doi.org/10.22271/plants.2022.v10.i5a.1465.

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3

Gupta, Rajiv, Satyendra Singh, Nitin Kumar, and Manvi. "Trichosanthes dioica Roxb.: An overview." Pharmacognosy Reviews 6, no. 11 (2012): 61. http://dx.doi.org/10.4103/0973-7847.95886.

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4

S, Bhattacharya. "In vitro Antioxidant Activity of Trichosanthes dioica Root." Journal of Natural & Ayurvedic Medicine 4, no. 4 (October 16, 2020): 1–5. http://dx.doi.org/10.23880/jonam-16000279.

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Trichosanthes dioica Roxb. (Cucurbitaceae), called pointed gourd in English, Potol in Bengali is a dioecious climber vine found wild throughout the plains of India and cultivated widely for its consumable fruits. The objective of the present study is to evaluate the in vitro antioxidant activity of hydroalcohol extract of roots from Trichosanthes dioica Roxb (TDA). In vitro antioxidant activity of TDA was assessed by DPPH, nitric oxide, hydroxyl radical, peroxynitrite and superoxide radical scavenging methods. TDA exhibited marked and concentration dependent free radical scavenging affect in all five in vitro models. The results from the present work demonstrated that T. dioica root possesses promising in vitro antioxidant effect which may provide the basis of its several activities in vivo.
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5

Sanjib, Bhattacharya, and Kanti Haldar Pallab. "Neuropharmacological properties of Trichosanthes dioica root." Chinese Journal of Natural Medicines 11, no. 2 (March 25, 2014): 158–63. http://dx.doi.org/10.3724/sp.j.1009.2013.00158.

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6

Rai, Prashant Kumar. "Therapeutic Phytoelemental Profile Of Trichosanthes Dioica." Advanced Materials Letters 1, no. 3 (December 1, 2010): 210–16. http://dx.doi.org/10.5185/amlett.2010.7142.

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7

Kabir, MA, and G. Kabir. "Metroglyph analysis in Trichosanthes dioica (Roxb.)." Journal of Bio-Science 25 (July 18, 2018): 67–72. http://dx.doi.org/10.3329/jbs.v25i0.37500.

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Morphological variation in eighteen lines of pointed gourd (Trichosanthes dioica Roxb.) was determined by Metroglyph method showing their genetic relationship. Assessment of variability of pointed gourd may help for successful utilization of its different attributes in developing suitable genotypes for yield and stability. A total of twelve quantitative characters were used for analyzing genetic variation. Arbitarily the clusters were found in the diagram but not in consolidated form. Cluster I was represented only by two lines. Almost similarly cluster II was found to be comprised of only three lines. On the contrary, cluster III contains thirteen lines of pointed gourd, although they were found to be located scattered showing their great morphological variations.J. bio-sci. 25: 67-72, 2017
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8

Bhattacharya, Sanjib, and Pallab Kanti Haldar. "Neuropharmacological properties of Trichosanthes dioica root." Chinese Journal of Natural Medicines 11, no. 2 (March 2013): 158–63. http://dx.doi.org/10.1016/s1875-5364(13)60043-6.

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9

Kumar, Tejmani, Prashant K. Rai, Abhishek K. Rai, Nilesh K. Rai, Awadhesh K. Rai, Christian G. Parigger, Geeta Watal, and Suman Yadav. "Elemental Laser-Plasma Analysis of Pointed Gourd Leaves for Diabetes Management." Foundations 2, no. 4 (October 26, 2022): 981–98. http://dx.doi.org/10.3390/foundations2040066.

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This interdisciplinary work communicates the identification and quantification of elements responsible for the bioactive potency of leaves from pointed gourd, trichosanthes dioica, using laser-induced breakdown spectroscopy (LIBS). Calibration-free LIBS determines the presence of various trace and major elements, their concentrations, and ratios in which they are present in the leaves. The presence of specific elemental ratios of magnesium/sodium and magnesium/potassium could be promising for managing diabetes mellitus. Variable doses of aqueous extract from trichosanthes dioica leaves are administered for determination of the most effective one. Based on encouraging results, the extract could be harvested to serve as anti-diabetic medication for diabetes and associated symptoms.
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10

Sinha, Sangram, Anupam Guha, and Rabindra Kumar Sinha. "Karyotype and Sex Expression in Trichosanthes dioica." CYTOLOGIA 68, no. 4 (2003): 357–61. http://dx.doi.org/10.1508/cytologia.68.357.

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11

Mythili, J. B., and Pious Thomas. "Micropropagation of pointed gourd (Trichosanthes dioica Roxb.)." Scientia Horticulturae 79, no. 1-2 (February 1999): 87–90. http://dx.doi.org/10.1016/s0304-4238(98)00201-5.

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12

Rai, Prashant Kumar, Sharad Kumar Gupta, Amrita Kumari Srivastava, Rajesh Kumar Gupta, and Geeta Watal. "A Scientific Validation of Antihyperglycemic and Antihyperlipidemic Attributes of Trichosanthes dioica." ISRN Pharmacology 2013 (July 25, 2013): 1–7. http://dx.doi.org/10.1155/2013/473059.

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The present study was undertaken to scientifically validate the antidiabetic activity of aqueous fruit extract of Trichosanthes dioica Roxb. (Family: Cucurbitaceae) which has been traditionally used for managing diabetes mellitus. This plant commonly known as “Sespadula” in English has not been explored scientifically so far for its glycemic potential except by our research group. The study was conducted with variable doses on normal, mild, and severe diabetics models, and several biochemical parameters including blood glucose level (BGL) were assessed. Maximum fall in BGL of 23.8% in normal rats and of 31.3% in mild diabetic rats was observed during their fasting blood glucose (FBG) and glucose tolerance test (GTT) with the dose of 1000 mg kg−1. In severely diabetic animals after 4 weeks treatment with FBG, postprandial glucose, total cholesterol, and triglyceride levels were reduced by 28.7, 30.7, 57.2, and 18.5%, whereas high density lipoprotein, total protein, hemoglobin, and body weight were increased by 33.0, 36.7, 15.7 and 16.7%, respectively. Moreover, urine sugar was reduced from +4 to +1. Thus, the study scientifically validates the traditional use of T. diocia in diabetes management and could be developed as an effective oral agent for treating diabetes mellitus and complications associated with it.
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13

Malek, M. A., M. O. Islam, and M. A. Bari Miah. "ARTIFICIAL SEED PRODUCTION IN POINTED GOURD (TRICHOSANTHES DIOICA ROXB.)." Bangladesh Journal of Plant Breeding and Genetics 21, no. 1 (June 30, 2008): 15–20. http://dx.doi.org/10.3329/bjpbg.v21i1.17044.

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Encapsulation of nodal segments was successfully developed for pointed gourd towards the formation of artificial seed with sodium alginate. Encapsulated nodal segments (artificial seed) were cultured in MS basal medium containing different concentrations and combinations of BAP and NAA to induce germination and shoot proliferation. Highest (95%) shoot formation was obtained in MS + 1.0 mg/l BAP followed by MS + 0.5 mg/l BAP. The encapsulated nodal segments also regenerated in vitro on different substrates. Frequency of plantlet formation was low on these substrates compared to plantlet development on MS media. Among these substrates, the percentage of plantlet formation was better on moist cotton (42%) followed by filter paper (35%). The hardened plants were transferred successfully to soil in the earthen pots. The protocol for encapsulating the nodal segments for the production of artificial seeds and their subsequent regeneration is a new area of research to develop in vitro conservation strategies for pointed gourd.DOI: http://dx.doi.org/10.3329/bjpbg.v21i1.17044
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14

Khandaker, Mahia, Saleha Akter, and Mohammad Zafar Imam. "Trichosanthes dioica Roxb.: A vegetable with diverse pharmacological properties." Food Science and Human Wellness 7, no. 1 (March 2018): 34–48. http://dx.doi.org/10.1016/j.fshw.2017.12.005.

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15

Shivhare, Yogesh, and Alok Pal Jain. "Assessment of Healing Potential of Formulated Herbal Cream on Burn Wound." Journal of Drug Delivery and Therapeutics 9, no. 4-s (February 5, 2020): 1191–94. http://dx.doi.org/10.22270/jddt.v9i4-s.3874.

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The current protocol of the study was planned to assess the healing potential of formulated herbal cream containing different medicinal plant extracts. Formulated herbal cream was containing the methanolic extract of Chenopodium album, Coccinia indica, Momordica dioica, Precitrullus fistulosus and Trichosanthes dioica with cream base. Formulated herbal cream was assessed pharmacologically for healing potential in burn wound model. The formulation showed a significantly higher contraction rate, shortened epithelialization period, better tensile strength and increase in hydroxyproline content in the burn wound model. Thus, it is concluded that formulation has the potential wound healing activity which justifying its use as wound healer. Keywords: Formulation, Burn, Wound, Contraction
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16

Howlader, Md Abu Hasan, Md Shamim Iqbal, SM Sirajul Islam, and MA Quader. "Phytochemical Constituents of Some Vegetables." Dhaka University Journal of Science 61, no. 2 (November 18, 2013): 147–51. http://dx.doi.org/10.3329/dujs.v61i2.17060.

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Alkaloids, terpenoids, tannins, saponins, phlobatannins, flavonoids, steroids, cardiac glycosides, sugar molecules, and amino acid distribution in four vegetables of Bangladesh origin belonging to the family of Cucurbitaceae were assessed and compared. The vegetables investigated were Luffa acutangula (Jhingga), Luffa cylindrica (Dhundul), Trichosanthes anguina (Chichingga) and Tricosanthes dioica (Potol). DOI: http://dx.doi.org/10.3329/dujs.v61i2.17060 Dhaka Univ. J. Sci. 61(2): 147-151, 2013 (July)
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17

Shivhare, Yogesh, and Alok Pal Jain. "Potential Emphasis of Formulated Herbal Cream on Wound Healing." Asian Journal of Pharmaceutical Research and Development 8, no. 1 (February 14, 2020): 73–77. http://dx.doi.org/10.22270/ajprd.v8i1.639.

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Aim: The present study was to formulate and evaluate the herbal cream comprising extracts of different medicinal plants. Experimental: The aqueous extract of all selected plants (Chenopodium album, Coccinia indica, Momordica dioica, Praecitrullus fistulosus and Trichosanthes dioica) were prepared by successive solvent extraction using soxhlet apparatus. Topical herbal cream was formulate and examined on different parameters like colour, consistency, pH, viscosity, spreadability and stability. Pharmacological evaluation of formulated herbal cream was done with excision and incision wound models. Results and Conclusion: Based on the resultant findings obtained from the different evaluation parameters, it can be concluded that prepared herbal formulation was stable and safe to use in wound healing activity.
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18

HASSAN, Jahidul, and Ikuo MIYAJIMA. "Morphological and Ecological Characteristics of Pointed Gourd (Trichosanthes dioica Roxb.)." Journal of the Faculty of Agriculture, Kyushu University 64, no. 2 (September 2, 2019): 183–89. http://dx.doi.org/10.5109/2339052.

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19

Bhattacharya, Sanjib, and Pallab Kanti Haldar. "Trichosanthes dioica Root Alleviates Arsenic Induced Myocardial Toxicity in Rats." Journal of Environmental Pathology, Toxicology and Oncology 32, no. 3 (2013): 251–61. http://dx.doi.org/10.1615/jenvironpatholtoxicoloncol.2013008541.

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20

Bhattacharya, Sanjib, and PallabK Haldar. "Evaluation of in vitro cytotoxic effect of Trichosanthes dioica root." Pharmacognosy Research 2, no. 6 (2010): 355. http://dx.doi.org/10.4103/0974-8490.75454.

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21

., R. B. Singandhupe, Edna Antony ., B. K. James ., P. Nanda ., and M. S. Behra . "Physiological Studies of Drip Irrigated Pointed Gourd (Trichosanthes dioica Roxb.)." Journal of Plant Sciences 1, no. 1 (December 15, 2005): 22–30. http://dx.doi.org/10.3923/jps.2006.22.30.

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22

Singandhup, R. B., Edna Antony, B. K. James, P. Nanda, and M. S. Behra. "Physiological Studies of Drip Irrigated Pointed Gourd (Trichosanthes dioica Roxb.)*." Journal of Plant Sciences 5, no. 1 (December 15, 2009): 41–49. http://dx.doi.org/10.3923/jps.2010.41.49.

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23

Zilani, Md Nazmul Hasan, Shaikh Jamal Uddin, Hemayet Hossain, Hazrina Hazni, Jamil A. Shilpi, and Md Golam Hossain. "Chemical characterization and bioactivity of Trichosanthes dioica edible shoot extract." Oriental Pharmacy and Experimental Medicine 18, no. 2 (May 7, 2018): 167–75. http://dx.doi.org/10.1007/s13596-018-0310-5.

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24

Solomon, Joy Ashish, Aditya Ganeshpurkar, Nilesh Shrivastava, Divya Bansal, and Nazneen Dubey. "Determination of Cucurbitacin B in Trichosanthes dioica Roxb by HPTLC." Pharmacognosy Communication 4, no. 2 (April 14, 2014): 8–12. http://dx.doi.org/10.5530/pc.2014.2.3.

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25

Ghosh, T., Y. Vashi, K. Barman, and L. I. Singha. "Novel Ribosome-inactivating Protein (RIP) Isolated from Trichosanthes dioica Induces Apoptosis in HeLa Cell Line." International Journal of Bio-resource and Stress Management 12, no. 3 (June 30, 2021): 165–69. http://dx.doi.org/10.23910/1.2021.2221.

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Ribosome-inactivating proteins (RIPs) are toxic N-glycosidases that depurinate eukaryotic and prokaryotic rRNAs and thus interrupt protein synthesis during translation. In the present study, a protein of around 32 kDa, supposedly a RIP isolated from Trichosanthes dioica, was assessed for its potential to induce apoptosis in HeLa cells. Cell viability assay was done to measure cell proliferation and survivability. It was observed that cells viability decreased with the increase of decrease in dilution, i.e. when the sample was an undiluted one, the viability decreased drastically and almost came to less than 10%. To further check whether the isolated RIP could induce apoptosis, HeLa cells were treated with the test RIP. Immunoblotting was carried out using PARP poly (ADP-ribose) polymerase (PARP-1), a 113 kDa nuclear enzyme, which is considered a hallmark of cells undergoing apoptosis. HeLa cells were further analyzed for loss of mitochondrial membrane potential with JC-1 dye, which is an early event during apoptosis. Increased PARP breakdown in the RIP treated cells indicates that cells undergoing apoptosis and progressive loss of red J-aggregate fluorescence indicate that the isolated RIP from Trichosanthes dioica induces apoptosis in HeLa cells. The ability of apoptosis induction is comparable to another known RIP from Momordica charantia, which was used as a positive control. Promising results from the present study warrants the isolated RIP to be further explored for anticancer activities.
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Komal, Rashmi. "In Vitro organogenesis of Trichosanthes dioica Roxb. Plantlets through callus culture." Journal of Indian Botanical Society 101, no. 1and2 (2021): 58–65. http://dx.doi.org/10.5958/2455-7218.2021.00002.4.

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27

Sarker, Dilip De, and Kalyan B. Datta. "Giemsa C-banding pattern in some cultivars of Trichosanthes dioica Roxb." CYTOLOGIA 52, no. 3 (1987): 419–23. http://dx.doi.org/10.1508/cytologia.52.419.

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Alom, MS, BL Nag, MN Islam, F. Ahmed, and S. Akther. "Performance of different crop species with pointed gourd (Trichosanthes dioica Roxb.)." Bangladesh Journal of Agricultural Research 38, no. 3 (November 11, 2013): 523–29. http://dx.doi.org/10.3329/bjar.v38i3.16979.

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The experiment was conducted at the Regional Agricultural Research Station, Jessore during the period from November 2008 to April 2010 to find out the suitable component crop and planting system under intercropping system with pointed gourd for higher yield and economic return. The treatment combinations were T1 = Pointed gourd (PG) sole, T2 = PG + radish + mungbean (1 row at the boarder of the bed) + amaranth (broadcast), T3 = PG + radish + mungbean (2 rows at the boarder of the bed) + shabuj shak (broadcast), T4 = PG + radish + Indian spinach (1 row at the boarder of the bed), T5 = PG + radish + Indian spinach (2 rows at the boarder of the bed) and T6 = PG + radish + mungbean: Indian spinach (1 : 1 row at the boarder of the bed). The fruit yield (26.27-30.50 t/ha) of pointed gourd did not affect by sole and different intercropping systems. The highest pointed gourd equivalent yield (68.02 t/ha), gross return (Tk.1020300/ha) and net return (Tk.631466/ha) and benefit cost ratio (2.62) was obtained from the intercropping combination of PG + radish + Indian spinach (2 rows at the boarder of the bed). DOI: http://dx.doi.org/10.3329/bjar.v38i3.16979 Bangladesh J. Agril. Res. 38(3): 523-529, September 2013
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29

Rai, Prashant Kumar, Sanjukta Chatterji, Nilesh K. Rai, Awadhesh K. Rai, Dane Bicanic, and Geeta Watal. "The Glycemic Elemental Profile of Trichosanthes dioica: A LIBS-Based Study." Food Biophysics 5, no. 1 (November 6, 2009): 17–23. http://dx.doi.org/10.1007/s11483-009-9139-2.

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30

Malek, M. A., M. A. Bari Miah, M. O. Islam, A. M. M. Mosiul Hoque, and R. Gomes. "GENETIC VARIABILITY, HERITABILITY AND GENETIC ADVANCE IN POINTED GOURD (Trichosanthes dioica Roxb.)." Bangladesh Journal of Plant Breeding and Genetics 20, no. 1 (June 30, 2007): 47–52. http://dx.doi.org/10.3329/bjpbg.v20i1.17026.

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Genetic variability, heritability in broad sense and expected genetic advance as percent of mean for fruit yield and nine characters were studied in 25 pointed gourd genotypes. Fruits per plant and fruit yield per plant showed maximum variability. Genotypic coefficient of variation was found high for fruit yield and number of fruits per plant. All the characters under study were highly heritable in nature. High heritability coupled with high genetic advance was observed for fruit yield and fruits per plant, which indicated that these characters are more reliable for effective selection.DOI: http://dx.doi.org/10.3329/bjpbg.v20i1.17026
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31

Alam, M. Badrul, M. Sarowar Hossain, N. Sultana Chowdhury, M. Asadujjama, Ronok Zahan, M. Monirul Islam, M. Ehsanul Haque Mazu, M. Ekramul Haque, and Anwarul Islam. "Antioxidant, Anti-inflammatory and Anti-pyretic Activities of Trichosanthes dioica Roxb. Fruits." Journal of Pharmacology and Toxicology 6, no. 5 (June 15, 2011): 440–53. http://dx.doi.org/10.3923/jpt.2011.440.453.

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32

Akter, Saleha, and Mohammad Imam. "Antioxidant, antidiarrhoeal and cytotoxic properties of aerial parts of Trichosanthes dioica Roxb." American Journal of Food and Nutrition 1, no. 3 (September 2011): 95–101. http://dx.doi.org/10.5251/ajfn.2011.1.3.95.101.

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33

Sultan, Nabil Ali Mohammed, and Musti J. Swamy. "Fluorescence quenching and time-resolved fluorescence studies on Trichosanthes dioica seed lectin." Journal of Photochemistry and Photobiology B: Biology 80, no. 2 (August 2005): 93–100. http://dx.doi.org/10.1016/j.jphotobiol.2005.03.003.

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Islam, Muhammad Torequl. "A literature-based phytochemical evidence and biological activities of Trichosanthes dioica Roxb." Oriental Pharmacy and Experimental Medicine 18, no. 2 (May 11, 2018): 77–85. http://dx.doi.org/10.1007/s13596-018-0305-2.

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Ashish Solomon, Joy, Aditya Ganeshpurkar, Vikas Pandey, Divya Bansal, and Nazneen Dubey. "Protective Effect of Trichosanthes Dioica Extract Against Gentamicin Induced Nephrotoxicity in Rats." Pharmacognosy Communications 6, no. 1 (January 1, 2016): 23–27. http://dx.doi.org/10.5530/pc.2016.1.4.

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., S. M. Abdul-Awal, Md Jahangir Alam ., Md Raihan Ali ., and Md Nabiul Hasan . "In vitro Propagation of Pointed Gourd (Trichosanthes dioica Roxb.) from Shoot Tips." Biotechnology(Faisalabad) 4, no. 3 (March 1, 2005): 221–24. http://dx.doi.org/10.3923/biotech.2005.221.224.

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37

Kumar, Sandesh, Vipin Kumar, Satya Prakash, Manoj Kumar Singh, Arvind Kumar, S. P. Singh, Deepak Kumar, and Vishal Gangwar. "Effect of Integrated Nutrients Management Practices on Growth Parameters of Pointed Gourd (Tricosanthes dioica)." International Journal of Environment and Climate Change 13, no. 8 (June 22, 2023): 2133–41. http://dx.doi.org/10.9734/ijecc/2023/v13i82172.

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Introduction and Aim: Pointed gourd (Trichosanthes dioica Roxb) is one of the most profitable and nutrient-rich summer crops. The present investigation entitled “Effect of Integrated Nutrients Management Practices on Growth and Yield of Pointed gourd (Tricosanthes dioica) cv. Papdi & Rudra’’ was carried and conducted at open field condition located at Horticulture Research Centre (HRC), at Sardar Vallabhbhai Patel University of Agriculture & Technology, Meerut U.P India during Kharif season of 2022-2023. Methods: The experiment was carried out in randomized block design keeping two varieties i.e. Papdi and Rudra with three replications. The experimental trial consists 10 different treatment. Discussion and Conclusion: All the treatments showed significant differences for most of the traits under study, the combination of T9 (Vermicompost @ 10 ton /hac + Jivamrit @8% Spray) followed by the treatment T10 (F.Y.M @ 15 ton/ha + Jivamrita @ 8% sprays) was best suited for the growth attributes of pointed gourd.: Hence, the above treatment can be suggested as a combination for getting higher growth of pointed gourd.
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38

Yadava, U. L., and S. K. Dhir. "In Vitro Regeneration of Trichosanthes from Shoot Tips." HortScience 30, no. 4 (July 1995): 871C—871. http://dx.doi.org/10.21273/hortsci.30.4.871c.

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The morphogenetic potential of parval or pointed gourd (Trichosanthes dioica Roxb.) shoot-tip explants was investigated to establish this species as a model tissue culture system. An effective multiple-shoot propagation method is described. Ten-millimeter shoot tips from young branches of greehouse-grown plants served as explants. They were initiated on a MS basal medium. Multiple shoots were encouraged by transferring established explants to a proliferation medium consisting of MSB + 1 mg BAP/liter, because lower concentrations of BAP (0.1 to 0.5 mg–liter–1) inhibited multiple shoot formation; however, the same concentrations promoted rooting in explants. Medium supplemented with 1 mg BAP/liter and 100 mg PVP/liter caused the best proliferation of shoot tips. Upon transferring to fresh medium of the same composition, these shoot tips elongated 24 cm with three to five nodes in 4 weeks of culturing. Shoot multiplication cultures were maintained by transferring segments of multiple-shoot clusters to medium containing 1 mg BAP/liter and 0.5 mg GA3/liter. Medium supplemented with TDZ inhibited the number of regenerating explants but enhanced the number of shoot buds. Eighty percent of these plantlets were successfully rooted on MS medium supplemented with 1 mg NAA/liter. Plantlets survived in potting soil and exhibited normal growth under mist in the greenhouse.
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39

Bhattacharya, Sanjib, and Pallab Kanti Haldar. "Trichosanthes dioica Fruit Extract Ameliorates Arsenic-Induced Brain Toxicity in Male Albino Rats." Journal of Environmental Pathology, Toxicology and Oncology 32, no. 2 (2013): 141–48. http://dx.doi.org/10.1615/jenvironpatholtoxicoloncol.2013007557.

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40

Ghosh, Tapu, Laishram Indira Singha, and Keshab Barman. "Isolation and Characterization of a Novel RIP from Trichosanthes dioica having Anticancer Activity." International Journal of Current Microbiology and Applied Sciences 9, no. 9 (September 10, 2020): 232–42. http://dx.doi.org/10.20546/ijcmas.2020.909.029.

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41

Bhattacharjee, Donal. "Ethylene Absorbents Improve the Shelf Life of Pointed Gourd (Trichosanthes dioica Roxb.) Fruits." International Journal of Pure & Applied Bioscience 5, no. 1 (March 5, 2017): 64–71. http://dx.doi.org/10.18782/2320-7051.2450.

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Bairy, KL, A. Meharban, I. SR Punita, and Shalini Adiga. "Hypoglycemic effect of aqueous extract of trichosanthes dioica in normal and diabetic rats." International Journal of Diabetes in Developing Countries 30, no. 1 (2010): 38. http://dx.doi.org/10.4103/0973-3930.60011.

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Khan, Salma, Md Mizanur Rahman, Fariha Kabir, Kamrun Nahar, Fariha Mamun, Shoumen Lasker, Nusrat Subhan, et al. "Trichosanthes dioica Roxb. prevents hepatic inflammation and fibrosis in CCl4-induced ovariectomized rats." Clinical Nutrition Experimental 33 (October 2020): 1–17. http://dx.doi.org/10.1016/j.yclnex.2020.07.001.

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Rai, Prashant Kumar, Dolly Jaiswal, Devendra K. Rai, Bechan Sharma, and Geeta Watal. "Effect of water extract of Trichosanthes dioica fruits in streptozotocin induced diabetic rats." Indian Journal of Clinical Biochemistry 23, no. 4 (October 2008): 387–90. http://dx.doi.org/10.1007/s12291-008-0085-4.

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45

Shivhare, Yogesh, Pradeep K. Singour, U. K. Patil, and R. S. Pawar. "Wound healing potential of methanolic extract of Trichosanthes dioica Roxb (fruits) in rats." Journal of Ethnopharmacology 127, no. 3 (February 2010): 614–19. http://dx.doi.org/10.1016/j.jep.2009.12.015.

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46

Bhattacharya, Sanjib, and Pallab Kanti Haldar. "Gastrointestinal effects of triterpenoid enriched extract of Trichosanthes dioica root in albino mice." Oriental Pharmacy and Experimental Medicine 12, no. 2 (December 28, 2011): 113–21. http://dx.doi.org/10.1007/s13596-011-0049-8.

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47

R, Kavitha. "ANTIDIABETIC AND ENZYMATIC ANTIOXIDANT POTENTIAL FROM ETHANOLIC EXTRACTS OF LEAF AND FRUIT OF TRICHOSANTHES DIOICA AND LEAF OF CLITORIA TERNATEA ON DIABETIC RATS INDUCED BY STREPTOZOTOCIN." Asian Journal of Pharmaceutical and Clinical Research 11, no. 5 (May 1, 2018): 233. http://dx.doi.org/10.22159/ajpcr.2018.v11i5.24434.

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Abstract:
Objective: To evaluate the antidiabetic and enzymatic antioxidant effects of ethanolic extracts of leaf and fruit of Trichosanthes dioica and leaf of Clitoria ternatea in streptozotocin (STZ)-induced diabetic rats.Methods: Male adult albino rats of Wistar strain equally divided into 11 groups of six rats each were assigned into non-diabetic and diabetic groups. Diabetes was induced in experimental animals by single dose intraperitoneal administration of STZ at a dose of 60 mg/kg body weight. Group I and II which served as non-diabetic and diabetic controls, respectively, received placebo treatment. The diabetic test Groups III to X were treated with either individual and combined ethanolic extracts of plant materials T. dioica and C. ternatea (200 and 400 mg/kg bw) and Group XI was treated with glibenclamide (600 μg/kg bw) for 28 days consecutively. After completion of experimental duration, the animals were sacrificed and collected serum, liver, and kidney were used for the evaluating therapeutic effects on the STZ-induced diabetic rats.Results: The ethanolic extracts of T. dioica (leaf and fruit) and C. ternatea (leaf) and glibenclamide significantly reduced the levels of lipid peroxidation (LPO) and significantly increased the activities of enzymatic antioxidant markers superoxide dismutase, catalase, and glutathione peroxidase in serum, liver, and kidney of diabetic rats.Conclusions: From the present study, it can be concluded that the combined extract of T. dioica fruit and C. ternatea leaf was found to be more effective in treating diabetes and increased activities of enzymatic antioxidants in diabetic-treated rats substantiate that the investigated drugs do extend a clear protective action against LPO in STZ-induced diabetic rats.
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Bhattacharya, Sanjib, and Pallab Kanti Haldar. "Chemopreventive Property of Trichosanthes dioica Root Against 3-Methylcholanthrene-induced Carcinogenesis in Albino Mice." Journal of Environmental Pathology, Toxicology and Oncology 31, no. 2 (2012): 109–19. http://dx.doi.org/10.1615/jenvironpatholtoxicoloncol.v31.i2.30.

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Jena, Anil Kumar, T. Suseela, T. S. K. K. Kiran Patro, and R. V. Sujatha. "Studies on Genetic Variability, Heritability and Genetic Advance in Pointed Gourd (Trichosanthes dioica Roxb.)." International Journal of Current Microbiology and Applied Sciences 6, no. 8 (August 10, 2017): 1857–63. http://dx.doi.org/10.20546/ijcmas.2017.608.219.

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Kharbanda, Chetna, Mohammad Alam, Hinna Hamid, Kalim Javed, Sameena Bano, Yakub Ali, Syed Nazreen, and Saqlain Haider. "Ameliorative Effects of Trichosanthes dioica Extract in Suppressing Inflammatory Mediators and Attenuating Oxidative Stress." Planta Medica 81, no. 05 (March 17, 2015): 348–56. http://dx.doi.org/10.1055/s-0035-1545726.

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