Academic literature on the topic 'Triazole and tetrazole'

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Journal articles on the topic "Triazole and tetrazole"

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Suresh, Lingala, P. Sagar Vijay Kumar, T. Vinodkumar, and G. V. P. Chandramouli. "Heterogeneous recyclable nano-CeO2 catalyst: efficient and eco-friendly synthesis of novel fused triazolo and tetrazolo pyrimidine derivatives in aqueous medium." RSC Advances 6, no. 73 (2016): 68788–97. http://dx.doi.org/10.1039/c6ra16307f.

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A ceria nanocatalyst was used for the one-pot, multicomponent condensation reaction of benzoylacetonitrile, aromatic aldehydes and 5-amino-triazole/tetrazole proceeding via C–C and C–N bond formation to deliver triazolo/tetrazolo[1,5-a]pyrimidines.
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Chandrasekhar, Attoor, Venkatachalam Ramkumar, and Sethuraman Sankararaman. "Palladium catalyzed carbonylative annulation of the C(sp2)–H bond of N,1-diaryl-1H-tetrazol-5-amines and N,4-diaryl-4H-triazol-3-amines to quinazolinones." Organic & Biomolecular Chemistry 16, no. 44 (2018): 8629–38. http://dx.doi.org/10.1039/c8ob02516a.

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Pd(ii) catalyzed direct C–H carbonylative annulation of N,1-diaryl-1H-tetrazol-5-amines and N,4-diaryl-4H-1,2,4-triazol-3-amines gave the corresponding triazole and tetrazole fused quinazolinones in good yields.
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Lysenko, Andrey B. "The heterobifunctional ligand 5-[4-(1,2,4-triazol-4-yl)phenyl]-1H-tetrazole and its role in the construction of a CdIImetal–organic chain structure." Acta Crystallographica Section C Crystal Structure Communications 68, no. 10 (September 18, 2012): m291—m294. http://dx.doi.org/10.1107/s0108270112038498.

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5-[4-(1,2,4-Triazol-4-yl)phenyl]-1H-tetrazole, C9H7N7, (I), an asymmetric heterobifunctional organic ligand containing triazole (tr) and tetrazole (tz) termini linked directly through a 1,4-phenylene spacer, crystallizes in the polar space groupPc. The heterocyclic functions, serving as single hydrogen-bond donor (tz) or acceptor (tr) units, afford hydrogen-bonded zigzag chains with no crystallographic centre of inversion. In the structure ofcatena-poly[[diaquacadmium(II)]bis{μ2-5-[4-(1,2,4-triazol-4-yl)phenyl]tetrazol-1-ido-κ2N1:N1′}], [Cd(C9H6N7)2(H2O)2]n, (II), the CdIIdication resides on a centre of inversion in an octahedral {N4O2} environment. In the equatorial plane, the CdIIpolyhedron is built up from four N atoms of two kinds, namely oftrans-coordinating tr and tz fragments [Cd—N = 2.2926 (17) and 2.3603 (18) Å], and the coordinating aqua ligands occupy the two apical sites. The metal centres are separated at a distance of 11.1006 (7) Å by means of the double-bridging tetrazolate anion,L−, forming a chain structure. The water ligands and tz fragments interact with one another, like a double hydrogen-bond donor–acceptor synthon, leading to a hydrogen-bonded three-dimensional array.
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Pavlov, Dmitry, Taisiya Sukhikh, Evgeny Filatov, and Andrei Potapov. "Facile Synthesis of 3-(Azol-1-yl)-1-adamantanecarboxylic Acids—New Bifunctional Angle-Shaped Building Blocks for Coordination Polymers." Molecules 24, no. 15 (July 26, 2019): 2717. http://dx.doi.org/10.3390/molecules24152717.

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For the first time, orthogonally substituted azole-carboxylate adamantane ligands were synthesized and used for preparation of coordination polymers. The angle-shaped ligands were prepared by the reaction of 1-adamantanecarboxylic acid and azoles (1H-1,2,4-triazole, 3-methyl-1H-1,2,4-triazole, 3,5-dimethyl-1H-1,2,4-triazole, 1H-tetrazole, 5-methyl-1H-tetrazole) in concentrated sulfuric acid. Variation of the solvent and substituents in azole rings allowed to prepare both 1D and 2D copper(II) and nickel(II) coordination polymers, [Cu2(trzadc)4(H2O)0.7]∙DMF∙0.3H2O, [Cu(trzadc)2(MeOH)]∙MeOH, [Ni(trzadc)2(MeOH)2] and [Cu2(mtrzadc)3(MeOH)]+NO3– (trzadc-3-(1,2,4-triazol-1-yl)-adamantane-1-carboxylic acid; mtrzadc-3-(3-methyl-1,2,4-triazol-1-yl)-adamantane-1-carboxylic acid) which were structurally characterized by single crystal X-ray diffraction. Complex [Cu(trzadc)2(MeOH)]∙MeOH was shown to act as a catalyst in the Chan-Evans-Lam arylation reaction.
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Ciesielski, Witold, and Anna Krenc. "Potentiometric Titration of Triazolethiols and Tetrazolethiols with Iodine in Alkaline Medium." Collection of Czechoslovak Chemical Communications 67, no. 8 (2002): 1193–99. http://dx.doi.org/10.1135/cccc20021193.

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The iodimetric determination of triazolethiols and tetrazolethiols in alkaline medium is presented. The volumetric titration with potentiometric end-point detection was applied. The range of determination, in which the error is lower than 1%, is 20-2 000 μmol for 1H-1,2,4-triazole-3-thiol (1), 25-1 000 μmol for 3-phenyl-1H-1,2,4-triazole-5-thiol (2), 25-500 μmol for 4-methyl-5-(trifluoromethyl)-4H-1,2,4-triazole-3-thiol (3), 50-500 μmol for 3-amino-1H-1,2,4-triazole-5-thiol (4), 10-1 000 μmol for sodium (5-mercapto-1H-tetrazol-1-yl)acetate (5), 125-500 μmol for 1-phenyl-1H-tetrazole-5-thiol (6) and 50-1 000 μmol for 1-(4-hydroxyphenyl)-1H-tetrazole-5-thiol (7). The relative standard deviation for all determinations was below 1%. The shape of potentiometric titration curve of 6 and 7 is noteworthy at higher concentrations of sodium hydroxide and depends on the type of the indicator electrode (platinum, gold). An introduction of iodine results in a strong potential drop. Some systems do not follow the Nernst equation.
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Dioukhane, Khadim, Younas Aouine, Salaheddine Boukhssas, Asmae Nakkabi, Hassane Faraj, and Anouar Alami. "Synthesis and Characterization of a Novel Biheterocyclic -amino Acid Precursor of the Triazole-Tetrazole Type, via the Copper (I) Catalyzed Alkyne-Azide Cycloaddition Reaction (CuAAC)." European Journal of Advanced Chemistry Research 2, no. 2 (March 26, 2021): 7–15. http://dx.doi.org/10.24018/ejchem.2021.2.2.53.

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In this paper, we describe the regioselective synthesis of a novel tri-heterocyclic compound, a biheterocyclic amino acid precursor, derived from both triazole and tetrazole. The key step of our synthesis approach was the Huigsen 1,3-dipolar cycloaddition reaction, catalyzed by the copper (I) formed in situ by reduction of Cu(II) salts (CuSO4), 5H2O) by sodium ascorbate, and using as dipole the oxazoline azide derivative 4-(azidomethyl)-4-ethyl-2-phenyl-4,5-dihydrooxazole (4) and as dipolarophile 5-(4-methoxyphenyl)-2-(prop-2-yn-1-yl)-2H-tetrazole (3). The Cu(I) catalysis allowed us to carry out the cycloaddition at room temperature during a reaction time of only 8 hours and also to selectively obtain the 1,4-regioisomer; one of the two possible isomers, with a yield of 90% after chromatography on a silica gel column (ether/hexane: 1/2), and recrystallization in an ether/acetone mixture. The desired compound, 4-ethyl-4-((4-((5-(4-methoxyphenyl)-2H-tetrazol-2-yl)methyl)-1H-1,2,3-triazol-1-yl)methyl)-2-phenyl-4,5-dihydrooxazole (5) was analyzed by 1D magnetic resonance spectroscopy (1H, 13C), and characterized physico-chemically by mass spectrometry and elemental analysis.
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Zhao, Gang, Chunlin He, Haixiang Gao, Gregory H. Imler, Damon A. Parrish, and Jean'ne M. Shreeve. "Improving the density and properties of nitrogen-rich scaffolds by the introduction of a C–NO2 group." New Journal of Chemistry 42, no. 19 (2018): 16162–66. http://dx.doi.org/10.1039/c8nj03472a.

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5,5′-(Nitromethylene)bis(1H-tetrazole) and 5,5′-(2-(nitromethyl)-2H-1,2,3-triazole-4,5-diyl)bis(1H-tetrazole) were synthesized by introducing a C–NO2 group to increase the density and detonation performance.
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Tiwari, Vibha, Jacob T. Bingham, Shubham Vyas, and Anand Singh. "Intermolecular fluoroamination of allenes towards substituted vinyl fluorides." Organic & Biomolecular Chemistry 18, no. 44 (2020): 9044–49. http://dx.doi.org/10.1039/d0ob01697g.

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Tang, Yongxing, Chunlin He, Gregory H. Imler, Damon A. Parrish, and Jean'ne M. Shreeve. "Design and synthesis of N-methylene-C linked tetrazole and nitramino-1,2,4-triazole: an approach to promising energetic materials." Journal of Materials Chemistry A 4, no. 36 (2016): 13923–29. http://dx.doi.org/10.1039/c6ta05057c.

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Hamdan, Fatima, Fatemeh Tahoori, and Saeed Balalaie. "Synthesis of novel cyclopeptides containing heterocyclic skeletons." RSC Advances 8, no. 59 (2018): 33893–926. http://dx.doi.org/10.1039/c8ra03899f.

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Dissertations / Theses on the topic "Triazole and tetrazole"

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Radies, Hendrik. "Tetrazole und Triazole als neuartige Oxidationsmittel in IR-Täuschkörpern." Diss., lmu, 2009. http://nbn-resolving.de/urn:nbn:de:bvb:19-113956.

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Madadi, Nikhil Reddy. "Synthesis and Biological Evaluation of Novel Resveratrol and Combretastatin A4 Derivatives as Potent Anti-Cancer Agents." UKnowledge, 2014. http://uknowledge.uky.edu/pharmacy_etds/42.

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Resveratrol has been reported as a potential anticancer agent but cannot be used as an antitumor drug due to its chemical and metabolic instability. We have designed and synthesized 184 novel compounds related to resveratrol in an attempt to produce more potent and drug-like molecules. We have identified a tetrazole analog of resveratrol, ST-145(a) as a lead anticancer agent from the resveratrol analog series of compounds with a GI50 value of less than 10nM against almost all the human cancer cell lines in the National Cancer Institute’s screening panel. In a separate study, we tested the hypothesis that the limited bioavailability of resveratrol, can be improved by synthesizing analogs which would be glucuronidated at a lower rate than resveratrol itself. We demonstrated that ST-05 and ST-12(a) exhibit lower glucuronidation profiles when compared to resveratrol and that these synthesized stilbenoids likely represent useful scaffolds for the design of efficacious resveratrol analogs. We have also initiated a new discovery program to identify selective CB1 and CB2 receptor ligands from a library of novel stilbene scaffolds structurally related to the resveratrol molecule. From the screened resveratrol analogs, two compounds were identified as selective CB2 and CB1 ligands. Compound ST-179 had 47-fold selectivity for CB2 (Ki = 284 nM) compared to CB1, while compound ST-160 was 2-fold selective for CB1 (Ki = 400 nM) compared to the CB2 receptor. These structural analogs have the potential for development as novel cannabinoid therapeutics for treatment of obesity and/or drug dependency. Combretastatin A4 (CA-4) is one of the most potent antiangiogenic and antimitotic agents of natural origin. However, CA-4 suffers from chemical instability due to cis-trans isomerism in solution. To circumvent this problem, we have developed a facile procedure for the synthesis of novel 4,5-diaryl-2H-1,2,3-triazoles as CA-4 analogs to constrain the molecule to its cis-configuration. Twenty three triazoles were prepared as CA-4 analogs and submitted for anticancer screening. Among these CA-4 analogs, ST-467 and ST-145(b) can be considered as lead anticancer agents from this series, and further investigation against various cancer cell types in vivo with this class of compound may provide novel therapeutic avenues for treatment.
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Sproll, Stefan Michael. "Investigation of Nitrogen-Rich Polymers based on tetrazoles and triazoles." Diss., lmu, 2010. http://nbn-resolving.de/urn:nbn:de:bvb:19-119590.

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Betzler, Franziska Maria. "Investigation of Nitrogen-Rich polymers based on cellulose, tetrazoles and triazoles." Diss., Ludwig-Maximilians-Universität München, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-179281.

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Betzler, Franziska Maria [Verfasser], and Thomas M. [Akademischer Betreuer] Klapötke. "Investigation of Nitrogen-Rich polymers based on cellulose, tetrazoles and triazoles / Franziska Maria Betzler. Betreuer: Thomas M. Klapötke." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2013. http://d-nb.info/1067055258/34.

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Zhang, Yixin. "Design and Synthesis of a Series of Redox Active Tetrazine and Triazine Based Transition Metal Complexes." Thesis, Université d'Ottawa / University of Ottawa, 2018. http://hdl.handle.net/10393/37233.

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The use of two different chelating redox active ligands, 2,6-bis(6-methyl-1,2,4,5-3-yl) pyridine (BTZP) and 2,6-bis-(5,6-dialkyl-1,2,4-triazin-3-yl)-pyridine (BTP) in heterometallic first row and second row transition metal chemistry has yielded two new families of redox active metal complexes. These complexes were found to exhibit interesting electrochemical and magnetic properties. In this thesis, Chapter 1 lays the foundation for the research presented within. This section covers the fundamentals of the ligand design, ligand synthesis and related coordination chemistry literature review. Chapters 2 and 3 report the results of the current thesis. In Chapter 2, the synthesis and characterization of a family of discrete molecules and supramolecular arrangements, employing the ligand BTZP, is presented. All of the complexes presented in Chapter 2 are successfully synthesized and characterized with electrochemical and magnetic studies. According to the electrochemical data, it is found that the classic “terpy-like” complexes with [Co(BTZP) 2]2+ formula fosters more stability in the redox process. In Chapter 3, a family of transition metal complexes with [M(BTP) 2]2+ (M=Fe or Co) inorganic cores were obtained through the employment of the ligand BTP with various anions. In addition, dimeric molecules with [CoX4(BTP)2] formula were also obtained by solvothermal synthesis. The complexes were also electrochemically characterized, with all the complexes capable of being reduced, while only [CoII(BTP)2] (ClO4)2 showed reversible redox process. Similar with BTZP, the series of BTP based complexes are also characterized through magnetic measurement. Only cobalt-based BTP complexes are paramagnetic, with [CoII(BTP)2]2+ being spin crossover active when BF4- and ClO4- are present. However, the presence of NCS- and halides lead to either antiferromagnetic interactions and ferromagnetic interactions dominating at different temperature regimes.
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Ihle, Andreas. "Synthese neuer makrocyclischer Triazolsysteme." Doctoral thesis, Universitätsbibliothek Chemnitz, 2006. http://nbn-resolving.de/urn:nbn:de:swb:ch1-200601537.

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In der vorliegenden Arbeit wird die Verwendbarkeit verschiedener Alkine bzw. organischer Azide für die katalysierte 1,3-dipolare Cycloaddition dokumentiert. Es wird gezeigt, dass Popargylazid eine Sonderstellung bezüglich dieser katalysierten Cycloaddition einnimmt, da es diese zu inhibieren vermag. Der Hauptschwerpunkt der Arbeit liegt in der Synthese makrocyclischer Triazolsysteme unter Verwendung der Cu(I)-katalysierten 1,3-dipolaren Cycloaddition. Durch die Entwicklung einer mehrstufigen Synthese gelingt die Darstellung eines makrocylischen Triazolsystems, das formal als cyclisches Tetramer von Propargylazid aufgefasst werden kann. Durch Übertragung des Syntheseprinzips auf andere Fünfring-Heterocyclen (Tetrazole, Imidazole), wird eine große Anzahl an makrocyclischen Verbindungen als potentielle Komplexliganden erzeugt. Der Vergleich der Zielprodukte liefert Aussagen über deren Eigenschaften, vor allem deren Löslichkeitsverhalten und deren Reaktivität. Anhand einer Kristallstruktur wird gezeigt, dass es sich um nichtplanare Verbindungen handelt, was aus den NMR-Messungen bei Raumtemperatur nicht hervorgeht. Des weiteren werden aus den Nebenprodukten des Syntheseweges ebenfalls neue heterocyclische Systeme gewonnen, die den Makrocyclen ähnliche Eigenschaften aufweisen. Ferner gelingt die Synthese einer neuartigen Käfigverbindung aus einem der erstmalig erzeugten Makrocyclen, deren Struktur kristallographisch belegt werden kann.
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Pellegatti, Laurent. "Méthodologie en chimie hétérocyclique et application à la synthèse d'inhibiteurs de kinases." Thesis, Orléans, 2010. http://www.theses.fr/2010ORLE2046.

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Le cancer constitue l’une des principales causes de mortalité, et représente, de ce fait aujourd’hui un problème de santé publique majeur. Depuis quelques années, les alcaloïdes marins représentent une source d’inspiration importante pour les chimistes en vue d’obtenir de nouveaux médicaments anticancéreux. Dans cette optique, des recherches effectuées au sein de notre laboratoire ont fait état de la synthèse d’analogues de ces alcaloïdes possédant une structure tris aromatique. Nous avons développé des molécules originale analogues de ces alcaloïdes disposant d’un hétérocycle central (1,2,4-triazine et imidazo[1,2-b][1,2,4,5]tétrazine) sur lequel sont greffés deux noyaux phényles diversement substitués. L’obtention de ces composés a également été l’occasion de développer de nouvelles méthodologies de synthèse. Ainsi une nouvelle réaction de type Buchwald-Hartwig sur des méthylsulfanyl-1,2,4-triazines a pu être mise au point ainsi qu’une méthode de CH arylation palladocatalysée sur le noyau imidazo[1,2-b][1,2,4,5]tétrazine. Une partie est aussi consacrée aux réactions multicomposants de type Groebke-Blackburn. Différentes évaluations pharmacologiques ont été réalisées, notamment des tests d’inhibition sur différentes kinases et de cytotoxicité sur diverses lignées cellulaires cancéreuses humaines
Cancer, one of the leading causes of death, represents today a major public health problem. Over the last few years, marine alkaloids represent a source of inspiration for chemists in order to obtain new anticancer drugs. For this purpose, as a part of our laboratory researches, analogues of marine alkaloids were synthesized possessing a tris-aromatic structure. We developed originals analogs of these alacaloïds formed by a central heterocycle core (1,2,4-triazine et imidazo[1,2-b][1,2,4,5]tetrazine) on wich is graft two arylic moiety variously substituted. Obtaining these compounds was also an opportunity to develop news synthetic methodologies. So a new Buchwald-Hartwig reaction type based on methylsulfanyl-1,2,4-triazines has been perfect, as palladocatalyzed CH arylation pathway on imidazo[1,2-b][1,2,4,5]tetrazine. A part is devoted to Groebke-Blackburn multicomponant reaction. Various pharmacological analyses were carried out in particular with inhibition of various kinases and cytotoxicity evaluation on various human cancer cell lines
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S, Venkatesan. "Synthesis and inhibition studies of steviamine stereoisomers, novel triazole and tetrazole-fused five membered iminocyclitols." Thesis, 2018. http://eprint.iitd.ac.in:80//handle/2074/7939.

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Radies, Hendrik [Verfasser]. "Tetrazole und Triazole als neuartige Oxidationsmittel in IR-Täuschkörpern / vorgelegt von Hendrik Radies." 2009. http://d-nb.info/100399329X/34.

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Book chapters on the topic "Triazole and tetrazole"

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Naik, Anil D., Antoine P. Railliet, Marinela M. Dîrtu, and Yann Garcia. "Coordination preference and magnetic properties of FeII assemblies with a bis-azole bearing 1,2,4-triazole and tetrazole." In ICAME 2011, 119–23. Dordrecht: Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-4762-3_15.

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Ostrovskii, Vladimir A., and Rostislav E. Trifonov. "Fluorinated Triazoles and Tetrazoles." In Fluorine in Heterocyclic Chemistry Volume 1, 459–513. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-04346-3_11.

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Gupta, Pankuri, and Abha Sharma. "Pharmacological Significance of Triazoles and Tetrazoles in Neurodegenerative Disease: An Overview." In N-Heterocycles, 355–93. Singapore: Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-19-0832-3_10.

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Jadhav, Popat M., A. B. Kanagare, Anand B. Dhirbassi, Atam B. Tekale, R. M. Borade, S. U. Tekale, Keshav Lalit Ameta, and R. P. Pawar. "Recent Advances in Nanocatalyzed Synthesis of Triazoles and Tetrazoles and Their Biological Studies." In Nanocatalysis, 177–200. New York: CRC Press, 2022. http://dx.doi.org/10.1201/9781003141488-8.

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Begtrup, Mikael. "Diazole, Triazole, and Tetrazole N-Oxides." In Advances in Heterocyclic Chemistry Volume 106, 1–109. Elsevier, 2012. http://dx.doi.org/10.1016/b978-0-12-396531-8.00001-8.

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Murumkar, Prashant R., and Rupesh V. Chikhale. "Vicinal Diaryl Triazoles and Tetrazoles." In Vicinal Diaryl Substituted Heterocycles, 191–219. Elsevier, 2018. http://dx.doi.org/10.1016/b978-0-08-102237-5.00006-7.

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Elashry, E. S. H., and N. Rashed. "1,2,4-Triazolo- and Tetrazolo[x,y-z]pyrimidines." In Advances in Heterocyclic Chemistry Volume 72, 127–224. Elsevier, 1998. http://dx.doi.org/10.1016/s0065-2725(08)60316-5.

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Grimshaw, James. "Photochemistry of Aryl Diazonium Salts, Triazoles and Tetrazoles." In CRC Handbookof Organic Photochemistry and Photobiology, Volumes 1 & 2, Second Edition. CRC Press, 2003. http://dx.doi.org/10.1201/9780203495902.ch43.

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"Photochemistry of Aryl Diazonium Salts, Triazoles and Tetrazoles." In CRC Handbook of Organic Photochemistry and Photobiology, Volumes 1 & 2, 829–46. CRC Press, 2003. http://dx.doi.org/10.1201/9780203495902-49.

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Gonçalves, Raoni Schroeder B., and Leandro Soter de Mariz e Miranda. "Copper catalysis in the synthesis of 1,2,3-triazoles and tetrazoles." In Copper in N-Heterocyclic Chemistry, 75–113. Elsevier, 2021. http://dx.doi.org/10.1016/b978-0-12-821263-9.00003-5.

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Conference papers on the topic "Triazole and tetrazole"

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Jovanović-Šanta, Suzana S., Aleksandar M. Oklješa, Antos B. Sachanka, Yaraslau U. Dzichenka, and Sergei A. Usanov. "17-SUBSTITUTED STEROIDAL TETRAZOLES – NOVEL LIGANDS FOR HUMAN STEROID-CONVERTING CYP ENZYMES." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.336js.

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In animal and human organisms, there are many enzymes, members of the family of heme- containing proteins, cytochromes P450 (CYPs), included in the biosynthesis and metabolism of many biomolecules, as cholesterol, bile acids, sex, and corticosteroid hormones, as well as in metabolism of drugs and xenobiotics. It is also well-known that different imidazole and triazole derivatives are efficient inhibitors of CYPs activity. In this study, we present in vitro screening of binding of novel androstane derivatives with tetrazole- containing substituents in position 17 to human recombinant steroid-converting CYP enzymes: CYP7A1, CYP7B1, CYP17A1, CYP19, and CYP21. Initial screening was performed using a high throughput screening approach, while the affinity of the ligands was analyzed using spectrophotometric titration. For some among tested compounds type I spectral response (substrate-like binding) for CYP7A1 selectively, while for one compound type II spectral response (inhibitor-like binding) for CYP21 were detected, with micromolar values of Kds. Interestingly, one compound with mixed spectral response was found to bind for CYP7B1, which means that there are two optimal positions of the ligand inside the protein active site. Such results could be useful in CYP-inhibiting drug development, during a fast, high-throughput screening of pharmacological potential of novel compounds, as well as in side- effects recognizing.
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Szymanowska, Anna, Kamila Buzun, Wojciech Szymanowski, Robert Czarnomysy, Agnieszka Gornowicz, Mariusz Mojzych, Anna Bielawska, and Krzysztof Bielawski. "The pro-apoptotic effect of novel pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine derivatives in HT-29 colon cancer cells." In RAD Conference. RAD Centre, 2021. http://dx.doi.org/10.21175/rad.abstr.book.2021.8.3.

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