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Journal articles on the topic 'Transit dose'

Author: Grafiati

Published: 4 June 2021

Last updated: 19 February 2022

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1

Palmer, A. "Impact of software changes: Transit dose and source position accuracy of the Eckert & Ziegler BEBIG GmbH MultiSource® high dose rate (HDR) brachytherapy treatment unit." Journal of Radiotherapy in Practice 12, no. 1 (August 2, 2012): 80–87. http://dx.doi.org/10.1017/s1460396912000192.

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AbstractPurpose: Medical device performance checks are essential following changes to control system software. This work investigates the effects of new software on the performance of a high dose rate (HDR) brachytherapy treatment unit.Methods and Materials: A performance assessment was undertaken of the Eckert & Ziegler BEBIG GmbH MultiSource® HDR treatment unit following software upgrade. Video recordings of source transits were used to calculate transit doses, and autoradiography used to measure source dwell positions. Results were compared to a previous study.1Results: All results show

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Giménez-Alventosa, Vicent, Javier Vijande, Facundo Ballester, and Jose Perez-Calatayud. "Transit dose comparisons for60Co and192Ir HDR sources." Journal of Radiological Protection 36, no. 4 (October 14, 2016): 858–64. http://dx.doi.org/10.1088/0952-4746/36/4/858.

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3

Persoon, L. C. G. G., M. Podesta, S. M. J. J. G. Nijsten, E. G. C. Troost, and F. Verhaegen. "Time-Resolved Versus Integrated Transit Planar Dosimetry for Volumetric Modulated Arc Therapy." Technology in Cancer Research & Treatment 15, no. 6 (July 9, 2016): NP79—NP87. http://dx.doi.org/10.1177/1533034615617668.

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Purpose: It is desirable that dosimetric deviations during radiation treatments are detected. Integrated transit planar dosimetry is commonly used to evaluate external beam treatments such as volumetric-modulated arc therapy. This work focuses on patient geometry changes which result in differences between the planned and the delivered radiation dose. Integrated transit planar dosimetry will average out some deviations. Novel time-resolved transit planar dosimetry compares the delivered dose of volumetric-modulated arc therapy to the planned dose at various time points. Four patient cases are

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4

Bouras, E. P., M. Camilleri, D. D. Burton, and S. McKinzie. "Selective stimulation of colonic transit by the benzofuran 5HT4 agonist, prucalopride, in healthy humans." Gut 44, no. 5 (May 1, 1999): 682–86. http://dx.doi.org/10.1136/gut.44.5.682.

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BACKGROUNDPrucalopride (R093877) is a selective and specific 5HT4 agonist, the first of a new chemical class of benzofurans, with gastrointestinal prokinetic activities in vitro.AIMSTo evaluate the effects of prucalopride on gastrointestinal and colonic transit.METHODSA validated scintigraphic technique was used to measure gastrointestinal and colonic transit over 48 hours in 50 healthy volunteers. For seven days, each subject received a daily dose of 0.5, 1, 2, or 4 mg prucalopride, or placebo in a double blind, randomised fashion. The transit test was performed over the last 48 hours.RESULTS

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Viramontes, Blanca E., Allison Malcolm, Michael Camilleri, Lawrence A. Szarka, Sanna McKinzie, Duane D. Burton та Alan R. Zinsmeister. "Effects of an α2-adrenergic agonist on gastrointestinal transit, colonic motility, and sensation in humans". American Journal of Physiology-Gastrointestinal and Liver Physiology 281, № 6 (1 грудня 2001): G1468—G1476. http://dx.doi.org/10.1152/ajpgi.2001.281.6.g1468.

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To characterize α2-adrenergic control of motor and sensory functions of gastrointestinal tract and colon, we studied dose-related effects of clonidine (placebo or up to 0.3 mg po) by random assignment in 55 healthy humans. Gastrointestinal transit was measured in all subjects; in 35, we assessed colonic compliance, tone, and sensations of gas and pain during phasic distensions. Clonidine did not significantly alter gastrointestinal or colonic transit, but it increased colonic compliance and reduced fasting tone without altering colonic response to a meal. Clonidine significantly reduced aggreg

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6

Anvari, Akbar, Seyed Mahmoud Reza Aghamiri, Seyed Rabi Mahdavi, Parham Alaei, and Mohammad Mohammadi. "Dosimetric properties of fluoroscopic EPID for transit dosimetry." Journal of Radiotherapy in Practice 14, no. 1 (October 30, 2014): 27–34. http://dx.doi.org/10.1017/s1460396914000405.

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AbstractThe aim of this work was to evaluate dose response of fluoroscopic EPID for transit dosimetry applications. Properties studied included warm up time, build-up thickness evaluation, dose history, linearity, stability, and short and long-term reproducibility of EPID response, as well as field size dependence.Pixel value matrices of electronic portal images in DICOM format were analysed in central and 8 off axis points using customised written codes in Matlab. In order to do this, nine 26×26 pixel matrices were selected as regions of interest, the regions represented by these arrays were

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7

Wong, Tony P. Y., Wasantha Fernando, Peter N. Johnston, and Ian F. Bubb. "Transit dose of an Ir-192 high dose rate brachytherapy stepping source." Physics in Medicine and Biology 46, no. 2 (December 21, 2000): 323–31. http://dx.doi.org/10.1088/0031-9155/46/2/304.

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8

Bastin, K. T., M. B. Podgorsak, B. R. Thomadsen, B. R. Paliwal, and T. J. Kinsella. "Transit dose in high dose rate brachytherapy: Direct measurements and clinical implications." International Journal of Radiation Oncology*Biology*Physics 24 (January 1992): 135. http://dx.doi.org/10.1016/0360-3016(92)90154-a.

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9

Puig, M. M., O. Pol, and W. Warner. "Interaction of Morphine and Clonidine on Gastrointestinal Transit in Mice." Anesthesiology 85, no. 6 (December 1, 1996): 1403–12. http://dx.doi.org/10.1097/00000542-199612000-00022.

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Background Combinations of drugs are frequently used to achieve effective analgesia while minimizing side effects. Although the analgesic effects of morphine and clonidine seem to be synergistic, few studies have investigated other effects. Their role in inhibiting gastrointestinal transit was evaluated using different methods of analysis. Methods Percentage inhibition of transit induced by morphine, clonidine, or their combination was measured in mice that had been given an intragastric charcoal meal. Dose-response curves were obtained for each drug individually; for morphine:clonidine at 1:3

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10

Winterton, S. S., and N. G. Tarr. "BASE TRANSIT TIME MINIMIZATION WITH FIXED BASE DOPANT DOSE." Solid-State Electronics 42, no. 4 (April 1998): 667–70. http://dx.doi.org/10.1016/s0038-1101(97)00252-9.

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11

Fonseca, G. P., G. Landry, B. Reniers, A. Hoffmann, R. A. Rubo, P. C. G. Antunes, H. Yoriyaz, and F. Verhaegen. "The contribution from transit dose for192Ir HDR brachytherapy treatments." Physics in Medicine and Biology 59, no. 7 (March 14, 2014): 1831–44. http://dx.doi.org/10.1088/0031-9155/59/7/1831.

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Fonseca, G. P., R. A. Rubo, R. A. Minamisawa, G. R. dos Santos, P. C. G. Antunes, and H. Yoriyaz. "Determination of transit dose profile for a192Ir HDR source." Medical Physics 40, no. 5 (April 30, 2013): 051717. http://dx.doi.org/10.1118/1.4802731.

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13

Camilleri, Michael, Maria Vazquez-Roque, Johanna Iturrino, Amy Boldingh, Duane Burton, Sanna McKinzie, Banny S. Wong, et al. "Effect of a glucagon-like peptide 1 analog, ROSE-010, on GI motor functions in female patients with constipation-predominant irritable bowel syndrome." American Journal of Physiology-Gastrointestinal and Liver Physiology 303, no. 1 (July 1, 2012): G120—G128. http://dx.doi.org/10.1152/ajpgi.00076.2012.

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The glucagon-like peptide 1 (GLP-1) analog ROSE-010 reduced pain during acute exacerbations of irritable bowel syndrome (IBS). Our objective was to assess effects of ROSE-010 on several gastrointestinal (GI) motor and bowel functions in constipation-predominant IBS (IBS-C). In a single-center, randomized, parallel-group, double-blind, placebo-controlled, dose-response study, we evaluated safety, pharmacodynamics, and pharmacokinetics in female patients with IBS-C. ROSE-010 (30, 100, or 300 μg sc) or matching placebo was administered once daily for 3 consecutive days and on 1 day 2–10 days late

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Seow, Kok-Min, Jyun-Lin Lee, Ming-Luen Doong, Seng-Wong Huang, Jiann-Loung Hwang, Wei-Ju Huang, Full-Young Chang, Low-Tone Ho, and Chi-Chang Juan. "Human chorionic gonadotropin regulates gastric emptying in ovariectomized rats." Journal of Endocrinology 216, no. 3 (November 28, 2012): 307–14. http://dx.doi.org/10.1530/joe-12-0421.

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Prolongation of gastrointestinal transit resulting in nausea and vomiting in pregnancy (NVP) is the most common phenomenon during the first trimester of pregnancy. Increased human chorionic gonadotropin (hCG) concentration during the first trimester is the most likely cause of NVP. The aim of this study was to investigate the effect of hCG on gastrointestinal transit and plasma concentrations of cholecystokinin (CCK) in ovariectomized (Ovx) rats. I.p. injection of hCG was used to evaluate the dose effect of hCG on gastrointestinal transit in Ovx rats. The CCK antagonist lorglumide was used to

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Grudell, April B. M., Michael Camilleri, Kim L. Jensen, Amy E. Foxx-Orenstein, Duane D. Burton, Michael D. Ryks, Kari L. Baxter та ін. "Dose-response effect of a β3-adrenergic receptor agonist, solabegron, on gastrointestinal transit, bowel function, and somatostatin levels in health". American Journal of Physiology-Gastrointestinal and Liver Physiology 294, № 5 (травень 2008): G1114—G1119. http://dx.doi.org/10.1152/ajpgi.00051.2008.

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β3-Adrenoceptors(β3-AR) are expressed by cholinergic myenteric neurons and β3-AR agonists are effective in experimental models of diarrhea. Our aim was to explore the effects of a β3-AR agonist, solabegron, on gastrointestinal transit, safety, bowel function, plasma somatostatin, and solabegron pharmacokinetics (PK) following single and multiple doses. In a single-center, double-blind, parallel-group trial, 36 healthy volunteers were randomized to oral solabegron (50 or 200 mg twice daily) or placebo. Transit was measured by a validated method (99mTc-labeled egg meal and 111In charcoal deliver

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16

Jeong, S., M. Yoon, D. W. Kim, W. K. Chung, and M. Chung. "EP-1557: Development of dose calculation algorithm in homogeneous phantom through the transit dose." Radiotherapy and Oncology 119 (April 2016): S722. http://dx.doi.org/10.1016/s0167-8140(16)32807-9.

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17

Calcina, Carmen S. Guzmán, Adelaide de Almeida, José R. Oliveira Rocha, Felipe Chen Abrego, and Oswaldo Baffa. "Ir-192 HDR transit dose and radial dose function determination using alanine/EPR dosimetry." Physics in Medicine and Biology 50, no. 6 (February 24, 2005): 1109–17. http://dx.doi.org/10.1088/0031-9155/50/6/005.

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18

Bastin, Kenneth T., Matthew B. Podgorsak, and Bruce R. Thomadsen. "The transit dose component of high dose rate brachytherapy: direct measurements and clinical implications." International Journal of Radiation Oncology*Biology*Physics 26, no. 4 (July 1993): 695–702. http://dx.doi.org/10.1016/0360-3016(93)90291-3.

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19

Sweetser, Seth, Michael Camilleri, Sara J. Linker Nord, Duane D. Burton, Lorna Castenada, Robert Croop, Gary Tong, Randy Dockens, and Alan R. Zinsmeister. "Do corticotropin releasing factor-1 receptors influence colonic transit and bowel function in women with irritable bowel syndrome?" American Journal of Physiology-Gastrointestinal and Liver Physiology 296, no. 6 (June 2009): G1299—G1306. http://dx.doi.org/10.1152/ajpgi.00011.2009.

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Corticotropin releasing factor (CRF), a mediator of stress response, alters gastrointestinal (GI) functions. Stress-related changes in colonic motility are blocked by selective CRF1 receptor antagonists. Our aim was to assess whether modulation of central and peripheral CRF1 receptors affects colonic transit and bowel function in female patients with diarrhea-predominant irritable bowel syndrome (D-IBS). This randomized, double-blind, placebo-controlled, 2-wk study evaluated the effects of oral pexacerfont (BMS-562086), a selective CRF1 receptor antagonist, 25 and 100 mg qd, on GI and colonic

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20

VAN NIEUWENHOVEN, M. A., E. A. M. DE SWART, H. M. VAN EIJK, N. E. P. DEUTZ, F. BROUNS, and R. J. M. BRUMMER. "Effects of pre- and post-absorptive factors on the lactulose/rhamnose gut permeability test." Clinical Science 98, no. 3 (February 9, 2000): 349–53. http://dx.doi.org/10.1042/cs0980349.

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It is assumed that the outcome of the lactulose/rhamnose gut permeability test is not influenced by pre- or post-absorptive factors. The aim of our study was to investigate the role of a pre-absorptive factor, i.e. small-intestinal transit, and a post-absorptive factor, i.e. renal clearance. Ten healthy male subjects were studied. Urinary lactulose and rhamnose excretion was measured after intraduodenal administration of lactulose and rhamnose following induction of increased intestinal permeability using chenodeoxycholic acid (chenodiol), in the absence and in the presence of accelerated inte

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21

Li, Qigui, Thomas G. Brewer, and James O. Peggins. "Anorectic Toxicity of Dih Ydroartemisinin, Artemether, and Arteether in Rats Following Multiple Intramuscular Doses." International Journal of Toxicology 17, no. 6 (October 1998): 663–76. http://dx.doi.org/10.1080/109158198225900.

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During studies of arteether (AE), artemether (AM), and dihydroartemisinin (DQHS) neurotoxicity, the effect of 7 daily intramuscular doses (25, 50, and 100 mg/ kg/d) of those antimalarial drugs on gastrointestinal function was investigated in rats. A modified Nichols' method was used to measure daily food and water consumption. To estimate gastric transit, the total length amaranth (administered 40 minutes prior to sacrifice) dye traveled through small intestine were measured, and to determine gastric retention, the tied-off stomach pouch was removed and the contents weighed 24 hours after the

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22

Bogaerts, Ria, Dominique Huyskens, Caroline Weltens, and Andrèe Dutreix. "Variation of relative transit dose profiles with patient–detector distance." Radiotherapy and Oncology 54, no. 1 (January 2000): 29–37. http://dx.doi.org/10.1016/s0167-8140(99)00172-3.

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23

Menon, Geetha V., Marco C. Carlone, and Ron S. Sloboda. "Transit dose contributions to intracavitary and interstitial PDR brachytherapy treatments." Physics in Medicine and Biology 53, no. 13 (June 11, 2008): 3447–62. http://dx.doi.org/10.1088/0031-9155/53/13/003.

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Osinski, M. A., P. Bass, and E. A. Gaumnitz. "Peripheral and central actions of orphanin FQ (nociceptin) on murine colon." American Journal of Physiology-Gastrointestinal and Liver Physiology 276, no. 1 (January 1, 1999): G125—G131. http://dx.doi.org/10.1152/ajpgi.1999.276.1.g125.

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Orphanin FQ (OFQ), also known as nociceptin, is a recently isolated endogenous peptide with a structure similar to the endogenous opioid peptides. The present study examines the actions of centrally administered OFQ on in vivo murine gastrointestinal and colonic transit as well as the actions of OFQ on the isolated colon. Intracerebroventricular injections of OFQ dose dependently inhibited colonic propulsive activity. OFQ inhibition of colonic propulsion was unaffected by coadministration of the competitive opioid receptor antagonist naltrexone. A subadditive response was observed when approxi

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25

Zakhary, Mark J., Christopher L. Deufel, and John P. Mullins. "Estimating Transit Dose for Nasobiliary High Dose Rate (HDR) Brachytherapy Using a Novel QA Device." Brachytherapy 17, no. 4 (July 2018): S128. http://dx.doi.org/10.1016/j.brachy.2018.04.238.

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Barone, F. C., J. F. Deegan, W. J. Price, P. J. Fowler, J. D. Fondacaro, and H. S. Ormsbee. "Cold-restraint stress increases rat fecal pellet output and colonic transit." American Journal of Physiology-Gastrointestinal and Liver Physiology 258, no. 3 (March 1, 1990): G329—G337. http://dx.doi.org/10.1152/ajpgi.1990.258.3.g329.

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Increased fecal pellet output that occurs during cold-restraint stress (CRS) was evaluated systematically. Free-feeding rats, which exhibit a reduced occurrence of gastric ulcers under these conditions, were studied. CRS significantly increased fecal pellet production and fluid content. However, the fecal output produced during CRS was not associated with increased gut secretory activity or somatic motor activity associated with cold restraint and did not occur in anesthetized animals. Cold and restraint stress were additive in producing increased fecal output. Significant dose-related decreas

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Ouwehand, A. C. "A review of dose-responses of probiotics in human studies." Beneficial Microbes 8, no. 2 (April 26, 2017): 143–51. http://dx.doi.org/10.3920/bm2016.0140.

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The probiotic definition requires the administration of an ‘adequate amount’ in order to obtain a health benefit. What that amount should be is not indicated. Here, an overview is given of studies that investigated the dose-response relation of probiotics in human interventions. Studies were divided in; meta-analyses, meta-analyses on specific probiotic strains, and studies testing two or more doses of a probiotic (combination) in the same study. Meta-analyses on the effect of probiotics on antibiotic associated diarrhoea (AAD) suggest a dose-response effect; for Clostridium difficile-associat

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Husein, Saddam, Marline Nainggolan, Yuandani Yuandani, and Irzal Fanany. "Evaluation of Antidiarrheal Activity of the Ethanol Extract Leucaena leucocephala (Lam) de Wit Seed." Open Access Macedonian Journal of Medical Sciences 8, A (April 25, 2020): 278–82. http://dx.doi.org/10.3889/oamjms.2020.4060.

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BACKGROUND: Leucaena leucocephala belongs to the Leguminosae/Fabaceae family. L. leucocephala seeds contain alkaloids, flavonoids, and tannins which according to the previous research have antidiarrhea activity. AIM: This study was investigate the antidiarrheal activity of the ethanol extracts of Leucaena leucocephala (Lam) de Wit seeds induced by oleum ricini and intestinal transit methods for rats. MATERIALS AND METHODS: L. leucocephala seeds were extracted by maceration with 80% ethanol. Evaluation of antidiarrheal extract activity was performed by induction of oleum ricini and

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Sallam, H. S., H. M. Oliveira, H. T. Gan, D. N. Herndon, and J. D. Z. Chen. "Ghrelin improves burn-induced delayed gastrointestinal transit in rats." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 292, no. 1 (January 2007): R253—R257. http://dx.doi.org/10.1152/ajpregu.00100.2006.

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Delayed gastrointestinal transit is common in patients with severe burn. Ghrelin is a potent prokinetic peptide. We aimed at testing the effect of ghrelin on burn-induced delayed gastrointestinal transit in rats. Gastric emptying (GE), intestinal transit (IT), and colonic transit (CT) studies were performed in male Sprague-Dawley rats. Rats were randomized into two main groups as follows: sham injury and ghrelin-treated burn injury with doses of 0, 2, 5, and 10 nmol/rat ip 6 h after burn. Sham/burn injury was induced under anesthesia. Rats received a phenol red meal 20 min following ghrelin in

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30

Wojcicka, J. B., R. Yankelevich, F. Trichter, and D. P. Fontenla. "Comparison of the transit dose components and source kinematics of three high dose rate afterloading systems." Medical Dosimetry 24, no. 1 (March 1999): 61–65. http://dx.doi.org/10.1016/s0958-3947(98)00051-x.

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31

Lin, Mu-Han, Tsi-Chian Chao, Chung-Chi Lee, Chuan-Jong Tung, Chie-Yi Yeh, and Ji-Hong Hong. "Measurement-based Monte Carlo dose calculation system for IMRT pretreatment and on-line transit dose verifications." Medical Physics 36, no. 4 (March 12, 2009): 1167–75. http://dx.doi.org/10.1118/1.3089790.

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Berry, S. L., R. Sheu, C. Polvorosa, and C. S. Wuu. "In Vivo Treatment Verification using EPID Transit Dose Images Created from Thru-Air Portal Dose Images." International Journal of Radiation Oncology*Biology*Physics 81, no. 2 (October 2011): S823—S824. http://dx.doi.org/10.1016/j.ijrobp.2011.06.1452.

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33

Cullen, JJ, R. Dotie, KS Ephgrave, MM Hinkhouse, and K. Broadhurst. "Changes in intestinal transit and absorption during endotoxemia are dose-dependent." Gastroenterology 114 (April 1998): A362. http://dx.doi.org/10.1016/s0016-5085(98)81466-2.

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Cullen, Joseph J., Robert C. Doty, Kimberly S. Ephgrave, Marilyn M. Hinkhouse, and Kimberly Broadhurst. "Changes in Intestinal Transit and Absorption during Endotoxemia Are Dose Dependent." Journal of Surgical Research 81, no. 1 (January 1999): 81–86. http://dx.doi.org/10.1006/jsre.1998.5452.

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Manabe, Noriaki, Michael Camilleri, Archana Rao, Banny S. Wong, Duane Burton, Irene Busciglio, Alan R. Zinsmeister, and Ken Haruma. "Effect of daikenchuto (TU-100) on gastrointestinal and colonic transit in humans." American Journal of Physiology-Gastrointestinal and Liver Physiology 298, no. 6 (June 2010): G970—G975. http://dx.doi.org/10.1152/ajpgi.00043.2010.

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Daikenchuto (TU-100) is a traditional Japanese (Kampo) medicine used to treat postoperative ileus. TU-100 dose dependently increases gastrointestinal (GI) motility by modulating cholinergic and serotonergic mechanisms in animal studies. The aim of this study was to evaluate the effects of orally administered TU-100 on GI and colonic transit and bowel function in healthy humans. In a randomized, parallel-group, double-blind, placebo-controlled, dose-response study, 60 healthy subjects were randomly assigned to placebo or TU-100 2.5 g or 5 g tid ingested immediately before meals for 5 consecutiv

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Saslow, S. B., J. S. Scolapio, M. Camilleri, L. A. Forstrom, G. M. Thomforde, D. D. Burton, J. Rubin, H. C. Pitot, and A. R. Zinsmeister. "Medium term effects of a new 5HT3 antagonist, alosetron, in patients with carcinoid diarrhoea." Gut 42, no. 5 (May 1, 1998): 628–34. http://dx.doi.org/10.1136/gut.42.5.628.

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Background—Carcinoid diarrhoea is associated with rapid small bowel and proximal colonic transit. Intravenous administration of a serotonin type 3 receptor (5HT3) antagonist restores postprandial colonic tone towards normal in carcinoid patients.Aims—To evaluate the medium term effects of an oral 5HT3 antagonist, alosetron, on symptoms, stool fat, and transit in patients with carcinoid diarrhoea.Methods—In 27 patients with carcinoid diarrhoea, symptoms were recorded daily and gastrointestinal transit was measured by scintigraphy in a three dose (0.1, 0.5, 2.0 mg, twice daily), randomised (1:1:

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Shen, Jun, Alison Boeckmann, and Andrew Vick. "Implementation of dose superimposition to introduce multiple doses for a mathematical absorption model (transit compartment model)." Journal of Pharmacokinetics and Pharmacodynamics 39, no. 3 (May 4, 2012): 251–62. http://dx.doi.org/10.1007/s10928-012-9247-3.

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Jeong, Seonghoon, Myonggeun Yoon, Dong Wook Kim, Weon Kuu Chung, and Mijoo Chung. "Development of a patient dose verification method that uses the transit dose measured with a glass dosimeter." Journal of the Korean Physical Society 70, no. 10 (May 2017): 948–55. http://dx.doi.org/10.3938/jkps.70.948.

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Deufel, Christopher L., John P. Mullins, and Mark J. Zakhary. "A quality assurance device for measuring afterloader performance and transit dose for nasobiliary high-dose-rate brachytherapy." Brachytherapy 17, no. 4 (July 2018): 726–31. http://dx.doi.org/10.1016/j.brachy.2018.03.005.

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Williams, C. L., J. M. Peterson, R. G. Villar, and T. F. Burks. "Corticotropin-releasing factor directly mediates colonic responses to stress." American Journal of Physiology-Gastrointestinal and Liver Physiology 253, no. 4 (October 1, 1987): G582—G586. http://dx.doi.org/10.1152/ajpgi.1987.253.4.g582.

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A new stress model in rats produced changes in intestinal function that resemble patterns of intestinal dysfunction associated with stress in humans: small intestinal transit was inhibited, large intestinal transit was stimulated, and fecal excretion was stimulated. To evaluate the role of corticotropin-releasing factor (CRF) in mediating the effects of stress on the intestine, we studied the actions of exogenous CRF on small and large intestinal transit in the rat and characterized the effects of pharmacological blockade of CRF receptors on stress-induced intestinal dysfunction. Administratio

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Persoon, L. C. G. G., S. M. J. J. G. Nijsten, F. J. Wilbrink, M. Podesta, J. A. D. Snaith, T. Lustberg, W. J. C. van Elmpt, F. van Gils, and F. Verhaegen. "Interfractional trend analysis of dose differences based on 2D transit portal dosimetry." Physics in Medicine and Biology 57, no. 20 (September 21, 2012): 6445–58. http://dx.doi.org/10.1088/0031-9155/57/20/6445.

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Guo, Jingnan, Cary Zeitlin, Robert F. Wimmer-Schweingruber, Donald M. Hassler, Arik Posner, Bernd Heber, Jan Köhler, et al. "Variations of dose rate observed by MSL/RAD in transit to Mars." Astronomy & Astrophysics 577 (May 2015): A58. http://dx.doi.org/10.1051/0004-6361/201525680.

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Monnikes, H., B. G. Schmidt, H. E. Raybould, and Y. Tache. "CRF in the paraventricular nucleus mediates gastric and colonic motor response to restraint stress." American Journal of Physiology-Gastrointestinal and Liver Physiology 262, no. 1 (January 1, 1992): G137—G143. http://dx.doi.org/10.1152/ajpgi.1992.262.1.g137.

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The role of corticotropin-releasing factor (CRF) in the paraventricular nucleus of the hypothalamus (PVN) in the control of gastric emptying of a nonnutrient meal and colonic transit was investigated in conscious fasted rats chronically implanted with hypothalamic cannulas and catheters in both the stomach and proximal colon. CRF (0.06-0.6 nmol) microinfused unilaterally into the PVN resulted in a dose-dependent inhibition of gastric emptying (0-51%) and stimulation of colonic transit (0-93%). CRF (0.6 nmol)-induced delay in gastric emptying was inhibited by 50% by subdiaphragmatic vagotomy or

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Oka, Victor Otu, Victor Udo Nna, Ememfon G. Inyang, and John B. Ikpe. "Methanolic extract of Malus domestica mitigates formalin - Induced derangements in small intestinal motility and transit." Asian Journal of Medical Sciences 5, no. 3 (February 25, 2014): 45–50. http://dx.doi.org/10.3126/ajms.v5i3.9106.

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Objective: This study was carried out to ascertain the effect of formalin ingestion on smallintestinal motility and transit, and the impact of treatment with Malus domestica on same.Methodology: Twenty albino wistar rats weighing 180 - 200 g were used for this study.The animals were randomly divided into 4 groups of 5 rats each. Group 1 served as control,group 2 - formalin treated group, group 3 - M. domestica treated group and group 4 - formalintreated group administered with M. domestica. The daily oral dose employed in this studywas 2.5mg/100g and 40mg/100g for formalin and M. domestica res

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Kim, Min Joo, Se Hee Min, Seon Young Shin, Mi Na Kim, Hakmo Lee, Jin Young Jang, Sun-Whe Kim, Kyong Soo Park, and Hye Seung Jung. "Attenuation of PERK enhances glucose-stimulated insulin secretion in islets." Journal of Endocrinology 236, no. 3 (March 2018): 125–36. http://dx.doi.org/10.1530/joe-17-0497.

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PERK is a pancreatic endoplasmic reticulum (ER) kinase. Its complete deletion in pancreatic β cells induces insulin deficiency; however, the effects of partial Perk suppression are unclear. We investigated the effect of partial PERK suppression using the specific PERK inhibitors GSK2606414 and GSK2656157. Low-dose GSK2606414 treatment for 24 h enhanced glucose-stimulated insulin secretion (GSIS), islet insulin content and calcium transit in mouse (at 40 nM) and human (at 50–100 nM) pancreatic islets. GSK2606414 also induced the expression of the ER chaperone BiP and the release of calcium from

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Gielkens, H. A. J., A. van den Biggelaar, J. Vecht, W. Onkenhout, C. B. H. W. Lamers, and A. A. M. Masclee. "Effect of intravenous amino acids on interdigestive antroduodenal motility and small bowel transit time." Gut 44, no. 2 (February 1, 1999): 240–45. http://dx.doi.org/10.1136/gut.44.2.240.

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BackgroundPatients on total parenteral nutrition have an increased risk of developing gallstones because of gall bladder hypomotility. High dose amino acids may prevent biliary stasis by stimulating gall bladder emptying.AimsTo investigate whether intravenous amino acids also influence antroduodenal motility.MethodsEight healthy volunteers received, on three separate occasions, intravenous saline (control), low dose amino acids (LDA), or high dose amino acids (HDA). Antroduodenal motility was recorded by perfusion manometry and duodenocaecal transit time (DCTT) using the lactulose breath hydro

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Chen, T. S., M. L. Doong, F. Y. Chang, S. D. Lee, and P. S. Wang. "Effects of sex steroid hormones on gastric emptying and gastrointestinal transit in rats." American Journal of Physiology-Gastrointestinal and Liver Physiology 268, no. 1 (January 1, 1995): G171—G176. http://dx.doi.org/10.1152/ajpgi.1995.268.1.g171.

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In vitro studies have shown that estrogen and progesterone can affect the contractile response and myoelectric activity of the gastrointestinal smooth muscle. The present study was designed to investigate the effect of sex steroid hormones on gastric emptying and gastrointestinal transit were assessed in rats 15 min after intragastric instillation of a test meal containing charcoal and 51Cr. Gastric emptying was determined by measuring the amount of labeled chromium contained in the small intestine as a percentage of the initial amount received. Gastrointestinal transit was evaluated by calcul

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Salamun, Sukri, Luluk Elvitaria, and Liza Trisnawati. "Quick Response Code untuk Monitoring Kehadiran Kuliah Dosen." SATIN - Sains dan Teknologi Informasi 6, no. 1 (June 26, 2020): 53–61. http://dx.doi.org/10.33372/stn.v6i1.585.

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Kelas Bersama dosen merupkan salah satu fasilitas yang ada di Universitas Abdurrab Pekanbaru, kelas ini digunakan oleh dosen-dosen yang mengajar mata kuliah teori. Dalam aktifitas yang sedang berjalan sebelum adanya system absensi ini para dosen masih menggunakan absensi tertulis yang mana aktifitas ini tidak efisiean dikarenakan terjadinya antrian jika dalam jam yang sama terdapat jumlah dosen yang mengajar sangat banyak. Oleh karena itu dibuatlah sebuah system absensi dengan Quick Response code atau yang lebih dikenal dengan QR code. System yang di buat akan di integrasikan melalui peraangka

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Samsom, Melvin, Lawrence A. Szarka, Michael Camilleri, Adrian Vella, Alan R. Zinsmeister, and Robert A. Rizza. "Pramlintide, an amylin analog, selectively delays gastric emptying: potential role of vagal inhibition." American Journal of Physiology-Gastrointestinal and Liver Physiology 278, no. 6 (June 1, 2000): G946—G951. http://dx.doi.org/10.1152/ajpgi.2000.278.6.g946.

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The amylin analog pramlintide delays gastric emptying in type I diabetics. The effects of multiple doses of pramlintide and the mechanism of action in non-amylin-deficient humans are unknown. We investigated the effects of pramlintide on gastrointestinal and colonic transit and on the plasma pancreatic polypeptide response to the meal in a parallel-group dose-response study with subjects randomized to placebo, or 30 or 60 μg (tid, sc) of pramlintide. Pramlintide delayed gastric emptying [half-time ( t½): 112 min (SE 8.7 min), 169 min (SE 12 min), or 177 min (SE 25 min) after placebo or 30- or

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Kinhikar, RajeshA, Sachin Patkar, ChandrashekharM Tambe, and DeepakD Deshpande. "On the transit dose from motorized wedge treatment in Equinox-80 telecobalt unit." Journal of Cancer Research and Therapeutics 3, no. 3 (2007): 140. http://dx.doi.org/10.4103/0973-1482.34014.

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