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Journal articles on the topic 'Trans-diagnostic'

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Author: Grafiati

Published: 10 December 2022

Last updated: 29 January 2023

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1

Arad, M., Y. Piontkewitz, N. Albelda, N. Wolff, and I. Weiner. "Lactational immune activation model: from trans-diagnostic risk to trans-diagnostic prevention." European Neuropsychopharmacology 27 (October 2017): S891—S892. http://dx.doi.org/10.1016/s0924-977x(17)31591-2.

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Newton, J. Richard. "Borderline personality disorder and eating disorders: a trans-diagnostic approach to unravelling diagnostic complexity." Australasian Psychiatry 27, no. 6 (June 3, 2019): 556–58. http://dx.doi.org/10.1177/1039856219852297.

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Objectives: This opinion paper considers co-morbid borderline personality disorder (BPD) and eating disorders and proposes that a trans-diagnostic approach looking at presenting problems and treatment approaches may be of value. Conclusions: Trans-diagnostic elements can be identified across the two syndromes. Trans-diagnostic elements appear to include some shared aetiological factors as well as some shared syndromal components. The shared syndromal components include problems with affect, interpersonal problems, problems with self-concept and impulsivity. The pathoplastic effects of culture, attitudes to fatness and the neurobiology of starvation and/or restriction of intake are crucial to integrate into the understanding of co-morbidity of these two disorders. Trans-diagnostic approaches to treatment lead to trans-diagnostic improvements across the two disorders.

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Dudley, Robert, Willem Kuyken, and Christine A. Padesky. "Disorder specific and trans-diagnostic case conceptualisation." Clinical Psychology Review 31, no. 2 (March 2011): 213–24. http://dx.doi.org/10.1016/j.cpr.2010.07.005.

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Meletis, Eleftherios, Ravikiran Keshavamurthy, Balbir Bagicha Singh Dhaliwal, Rabinder Singh Aulakh, Navneet Dhand, and Polychronis Kostoulas. "Evaluation of the sensitivity and specificity of three diagnostic tests for Coxiella burnetii infection in cattle and buffaloes in Punjab (India) using Bayesian latent class analysis." PLOS ONE 17, no. 5 (May 5, 2022): e0254303. http://dx.doi.org/10.1371/journal.pone.0254303.

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Q Fever is a zoonotic disease of significant animal and public health concern, caused by Coxiella burnetii (C. burnetii), an obligate intracellular bacterium. This study was done to evaluate the diagnostic sensitivity (DSe) and diagnostic specificity (DSp) of three diagnostic methods to diagnose C. burnetii infection in cattle and buffaloes in Punjab, India: an indirect ELISA method applied in serum samples and a trans-Polymerase Chain Reaction (trans-PCR) technique applied in milk samples and genital swabs, using a Bayesian latent class analysis. Conditional independence was assumed between the tests, given (i) the different biological principle of ELISA and trans-PCR and (ii) the fact that the trans-PCR was performed on different tissues. The ELISA method in the serum samples showed the highest DSe of 0.97 (95% Probability Intervals (PIs): 0.93; 0.99) compared to the trans-PCR method applied in milk samples 0.76 (0.63; 0.87) and genital swabs 0.73 (0.58; 0.85). The DSps of all tests were high, with trans-PCR in genital swabs recording the highest DSp of 0.99 (0.98; 1), while the DSp of trans-PCR in milk samples and ELISA in serum samples were 0.97 (0.95; 0.99) and 0.95 (0.93; 0.97) respectively. The study results show that none of the applied tests are perfect, therefore, a testing regimen based on the diagnostic characteristic of the tests may be considered for diagnosis of C. burnetii.

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Shivam, Dr Shekhar, Dr R. S. Kharat Dr. R.S. Kharat, Dr Rachit Goel, and Dr Mihir Birnale. "Trans Rectal Ultrasonography as A Diagnostic Modality in Evaluation of Prostatic Symptoms." Indian Journal of Applied Research 4, no. 3 (October 1, 2011): 355–56. http://dx.doi.org/10.15373/2249555x/mar2014/110.

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Gillan, C. M., N. A. Fineberg, and T. W. Robbins. "A trans-diagnostic perspective on obsessive-compulsive disorder." Psychological Medicine 47, no. 9 (March 27, 2017): 1528–48. http://dx.doi.org/10.1017/s0033291716002786.

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Progress in understanding the underlying neurobiology of obsessive-compulsive disorder (OCD) has stalled in part because of the considerable problem of heterogeneity within this diagnostic category, and homogeneity across other putatively discrete, diagnostic categories. As psychiatry begins to recognize the shortcomings of a purely symptom-based psychiatric nosology, new data-driven approaches have begun to be utilized with the goal of solving these problems: specifically, identifying trans-diagnostic aspects of clinical phenomenology based on their association with neurobiological processes. In this review, we describe key methodological approaches to understanding OCD from this perspective and highlight the candidate traits that have already been identified as a result of these early endeavours. We discuss how important inferences can be made from pre-existing case-control studies as well as showcasing newer methods that rely on large general population datasets to refine and validate psychiatric phenotypes. As exemplars, we take ‘compulsivity’ and ‘anxiety’, putatively trans-diagnostic symptom dimensions that are linked to well-defined neurobiological mechanisms, goal-directed learning and error-related negativity, respectively. We argue that the identification of biologically valid, more homogeneous, dimensions such as these provides renewed optimism for identifying reliable genetic contributions to OCD and other disorders, improving animal models and critically, provides a path towards a future of more targeted psychiatric treatments.

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Delebecq, T., M. Bourneville, F. Guillemot, and T. Dugué. "Diagnostic d’une hernie interne trans-mésocolique par tomodensitométrie." Journal de Chirurgie 141, no. 5 (September 2004): 332. http://dx.doi.org/10.1016/s0021-7697(04)95355-0.

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Mu, Xixi, Yue Zhong, Xuan Zhang, and Changjun Qu. "Early Diagnosis Value of DCE-MRI Hemodynamic Parameters in Hepatocellular Carcinoma." Journal of Oncology 2022 (May 13, 2022): 1–9. http://dx.doi.org/10.1155/2022/9556589.

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Objective. To probe into the early diagnosis value of transfer coefficient ( K trans ) and rate constant ( K ep ) of the dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) hemodynamic parameters in patients with hepatocellular carcinoma (HCC). Methods. Fifty patients with HCC diagnosed in our hospital from May 2017 to May 2020 were studied retrospectively as the patient group (PG), and 45 cases with benign liver nodules diagnosed in our hospital during the same period were collected as the control group (CG). K trans , K ep , and AFP levels were compared between PG and CG. The diagnostic value of K trans and K ep in HCC were observed, and their correlations with patient clinical data were analyzed. The diagnostic value of K trans and K ep combined with AFP in clinical staging, differentiation degree, and distant metastasis was compared. Results. K trans , K ep , and AFP were notably higher in cases than in controls ( P < 0.05 ), indicating their high diagnostic value in HCC. K trans and K ep present elevated expression in HCC patients with clinical stage III-IV, low differentiation, and distant metastasis ( P < 0.05 ). Furthermore, it is found that the combined detection with either K trans or K ep can improve the clinical diagnostic value of AFP in the clinical stage and differentiation of HCC. However, the combined diagnosis showed little effect in raising the sensitivity of AFP in distant metastasis. Conclusion. DCE-MRI hemodynamic parameters K trans and K ep have high clinical value in early diagnosis and differentiation of HCC patients.

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Scott, Jan, Jacob J. Crouse, Nicholas Ho, Frank Iorfino, Nicholas Martin, Richard Parker, John McGrath, Nathan A. Gillespie, Sarah Medland, and Ian B. Hickie. "Early expressions of psychopathology and risk associated with trans-diagnostic transition to mood and psychotic disorders in adolescents and young adults." PLOS ONE 16, no. 6 (June 4, 2021): e0252550. http://dx.doi.org/10.1371/journal.pone.0252550.

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Objectives The heterogeneity and comorbidity of major mental disorders presenting in adolescents and young adults has fostered calls for trans-diagnostic research. This study examines early expressions of psychopathology and risk and trans-diagnostic caseness in a community cohort of twins and non-twin siblings. Methods Using data from the Brisbane Longitudinal Twin Study, we estimated median number of self-rated psychiatric symptoms, prevalence of subthreshold syndromes, family history of mood and/or psychotic disorders, and likelihood of subsequent trans-diagnostic caseness (individuals meeting diagnostic criteria for mood and/or psychotic syndromes). Next, we used cross-validated Chi-Square Automatic Interaction Detector (CHAID) analyses to identify the nature and relative importance of individual self-rated symptoms that predicted trans-diagnostic caseness. We examined the positive and negative predictive values (PPV; NPV) and accuracy of all classifications (Area under the Curve and 95% confidence intervals: AUC; 95% CI). Results Of 1815 participants (Female 1050, 58%; mean age 26.40), more than one in four met caseness criteria for a mood and/or psychotic disorder. Examination of individual factors indicated that the AUC was highest for subthreshold syndromes, followed by family history then self-rated psychiatric symptoms, and that NPV always exceeded PPV for caseness. In contrast, the CHAID analysis (adjusted for age, sex, twin status) generated a classification tree comprising six trans-diagnostic symptoms. Whilst the contribution of two symptoms (need for sleep; physical activity) to the model was more difficult to interpret, CHAID analysis indicated that four self-rated symptoms (sadness; feeling overwhelmed; impaired concentration; paranoia) offered the best discrimination between cases and non-cases. These four symptoms showed different associations with family history status. Conclusions The findings need replication in independent cohorts. However, the use of CHAID might provide a means of identifying specific subsets of trans-diagnostic symptoms representing clinical phenotypes that predict transition to caseness in individuals at risk of onset of major mental disorders.

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Sisson, S. A., and Y. Fan. "A distance-based diagnostic for trans-dimensional Markov chains." Statistics and Computing 17, no. 4 (August 1, 2007): 357–67. http://dx.doi.org/10.1007/s11222-007-9025-z.

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Li, Ming, Xiaodan Xu, Kaijian Xia, Heng Jiang, Jianlong Jiang, Jinbing Sun, and Zhihua Lu. "Comparison of Diagnostic Performance between Perfusion-Related Intravoxel Incoherent Motion DWI and Dynamic Contrast-Enhanced MRI in Rectal Cancer." Computational and Mathematical Methods in Medicine 2021 (July 29, 2021): 1–7. http://dx.doi.org/10.1155/2021/5095940.

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This study was aimed to determine the diagnostic performance of perfusion-related parameters derived from intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) by comparing them with quantitative parameters from dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) based on differentiation grades of rectal cancer. We retrospectively analyzed 98 patients with rectal cancer. Perfusion-related IVIM parameters ( D ∗ , f , and f · D ∗ ) and quantitative DCE parameters ( K trans , K ep , V e , and V p ) were obtained by plotting the volume-of-interest on in-house software. Furthermore, we compared the difference and diagnostic performance of all well-moderately and poorly differentiated rectal cancer parameters. Finally, we analyzed the correlation between those DCE and IVIM parameters and pathological differentiation grade. The values of f , K trans , and K ep significantly differentiated poor and well-moderate rectal cancers. K trans achieved the highest area under the curve (AUC) value compared to perfusion-related IVIM and DCE parameters. Furthermore, K trans showed a better correlation with pathological differentiation grade than f . The diagnostic efficiency of DCE-MRI was greater than perfusion-related IVIM parameters. The f value derived from perfusion-related IVIM offered a diagnostic performance similar to DCE-MRI for patients with renal insufficiency.

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Davy, Zowie, Anniken Sørlie, and Amets Suess Schwend. "Democratising diagnoses? The role of the depathologisation perspective in constructing corporeal trans citizenship." Critical Social Policy 38, no. 1 (September 25, 2017): 13–34. http://dx.doi.org/10.1177/0261018317731716.

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In the scope of the current revision process of the diagnostic manuals Diagnostic and Statistical Manual of Mental Disorders (DSM) and International Statistical Classification of Diseases and Other Health Problems (ICD), an international trans depathologisation movement has emerged that demands, among other claims, the removal of a diagnostic classification of gender transition processes as a mental disorder. The call for submissions launched by the American Psychiatric Association (APA) and World Health Organization (WHO) seems to provide the opportunity for a participation of civil society in the DSM and ICD revision processes. These developments open up a number of questions for us that will be discussed in this article. We conducted a meta-narrative review to explore the trans depathologisation movement’s contribution to the DSM and ICD revision process, uncover evidence of a ‘democratised turn’ in the process and review depathologisation proposals implemented in trans healthcare practices, human rights frameworks and legal gender recognition processes. We argue that the trans depathologisation movement has had little impact on medical practices in trans healthcare. However, there is some movement in local health services towards an informed consent model for limited healthcare interventions. Within some European and South/Central American legal frameworks, the depathologisation movement’s demands to free legal gender recognition from medical interventions and examinations have, in different degrees, been incorporated into legal recommendations and enacted in some recent gender recognition laws.

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Carter, Rowena, and Dominic H. ffytche. "On visual hallucinations and cortical networks: a trans-diagnostic review." Journal of Neurology 262, no. 7 (March 13, 2015): 1780–90. http://dx.doi.org/10.1007/s00415-015-7687-6.

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Benameur, H., C. Chaves, A. C. Masquelet, A. Sautet, and A. Cambon-Binder. "Trans-tendinous flexor digitorum profundus ruptures: Diagnostic and surgical challenges." Hand Surgery and Rehabilitation 37, no. 2 (April 2018): 126–27. http://dx.doi.org/10.1016/j.hansur.2017.11.006.

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15

Tricia Seow, Xing Fang, and Claire Gillan. "F79. Confidence and Action in Trans-Diagnostic Psychiatric Symptom Dimensions." Biological Psychiatry 85, no. 10 (May 2019): S243. http://dx.doi.org/10.1016/j.biopsych.2019.03.616.

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Palwa, Abdur Rahim, Uzma Nisar, Mobeen Shafique, Omer Aamir, Sidra Riaz, Aown Raza Shah Bukhari, and Mehwish Razzaq. "The Accuracy of Transabdominal Ultrasound (TAUS) in Detection of Choledocholithiasis Keeping Magnetic Resonance Cholangiopancreatography (MRCP) as Gold Standard." Pakistan Armed Forces Medical Journal 72, no. 2 (April 30, 2022): 485–89. http://dx.doi.org/10.51253/pafmj.v72i2.4365.

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Objective: To assess the diagnostic accuracy of trans-abdominal ultrasound (TAUS) in detecting choledocholithiasis, keeping MRCP as the gold standard. Study Design: Cross-sectional study. Place and Duration of Study: Department of Magnetic Resonance Imaging, Armed Forces Institute of Radiology & Imaging, Pak Emirates Military Hospital, Rawalpindi Pakistan, from Jun 2018 to May 2019. Methodology: 102 patients of either gender, age 20-85 years with the clinical suspicion of choledocholithiasis and obstructive jaundice were included. Trans-abdominal ultrasonography was performed for radiological detection of disease. All selected cases then underwent MRCP for confirmation of findings. Results: Mean age of the patients was 54.27 ± 15.14 years. 47 patients (46.1%) were males, and 55 (53.9%) were females. All patients were subjected to trans-abdominal ultrasound and MRCP. TAUS showed choledocholithiasis in 82 (80.3%) patients. MRCP confirmed choledocholithiasis in 81 (79.4%) cases, whereas 21 (20.5%) revealed no choledocholithiasis. Overall sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of TAUS were 96%, 80.9%, 95%, 85% & 87.86%, respectively. Conclusion: Diagnostic accuracy of trans-abdominal ultrasonography in detecting choledocholithiasis is significantly high enough to be used as a first-line imaging modality as MRCP is available only in specialised care centres.

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Hansrani, Vivak, Zainab Dhorat, and Charles N. McCollum. "Diagnosing of pelvic vein incompetence using minimally invasive ultrasound techniques." Vascular 25, no. 3 (September 29, 2016): 253–59. http://dx.doi.org/10.1177/1708538116670499.

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Background Pelvic vein incompetence is a cause for pelvic pain and recurrent varicose veins in women. The gold standard diagnostic method is reflux venography involving radiation, nephrotoxic contrast and jugular puncture. Trans-vaginal ultrasound (TVU) is increasingly being used as a diagnostic tool for pelvic vein incompetence. Methods Fifty women with clinical suspicion of pelvic vein incompetence and aged between 18 and 55 years were recruited prospectively over two years at a large UK University Teaching Hospital. Trans-vaginal ultrasound was performed using a standardised protocol which included assessment of the ovarian and internal iliac veins bilaterally in the supine and semi-standing position with provocative manoeuvres. Diagnostic readability and inter-observer variability was determined. Results Mean (range) age of 43 (23–51). Visibility of all four pelvic veins was better in the supine position compared with semi-standing position (76% vs 64%). Pelvic vein incompetence was identified in 34 of 50 (68%) women in the supine position compared with 38 of 50 (76%) women in the semi-standing position. Pelvic vein incompetence was demonstrated in 35 of 50 (70%) women with Valsalva manoeuvre. Inter-observer variability was 0.84 (kappa, very good agreement, p = 0.001). Conclusion Trans-vaginal ultrasound is effective at demonstrating pelvic vein incompetence. All trans-vaginal ultrasound protocols should include assessment of pelvic veins in the supine and semi-standing position with Valsalva manoeuvre.

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Chamberlain, Samuel R., Jeggan Tiego, Leonardo F. Fontenelle, Roxanne Hook, Linden Parkes, Rebecca Segrave, Tobias U. Hauser, et al. "Fractionation of impulsive and compulsive trans-diagnostic phenotypes and their longitudinal associations." Australian & New Zealand Journal of Psychiatry 53, no. 9 (April 19, 2019): 896–907. http://dx.doi.org/10.1177/0004867419844325.

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Objective: Young adulthood is a crucial neurodevelopmental period during which impulsive and compulsive problem behaviours commonly emerge. While traditionally considered diametrically opposed, impulsive and compulsive symptoms tend to co-occur. The objectives of this study were as follows: (a) to identify the optimal trans-diagnostic structural framework for measuring impulsive and compulsive problem behaviours, and (b) to use this optimal framework to identify common/distinct antecedents of these latent phenotypes. Method: In total, 654 young adults were recruited as part of the Neuroscience in Psychiatry Network, a population-based cohort in the United Kingdom. The optimal trans-diagnostic structural model capturing 33 types of impulsive and compulsive problem behaviours was identified. Baseline predictors of subsequent impulsive and compulsive trans-diagnostic phenotypes were characterised, along with cross-sectional associations, using partial least squares. Results: Current problem behaviours were optimally explained by a bi-factor model, which yielded dissociable measures of impulsivity and compulsivity, as well as a general disinhibition factor. Impulsive problem behaviours were significantly explained by prior antisocial and impulsive personality traits, male gender, general distress, perceived dysfunctional parenting and teasing/arguments within friendships. Compulsive problem behaviours were significantly explained by prior compulsive traits and female gender. Conclusion: This study demonstrates that trans-diagnostic phenotypes of 33 impulsive and compulsive problem behaviours are identifiable in young adults, utilising a bi-factor model based on responses to a single questionnaire. Furthermore, these phenotypes have different antecedents. The findings yield a new framework for fractionating impulsivity and compulsivity, and suggest different early intervention targets to avert emergence of problem behaviours. This framework may be useful for future biological and clinical dissection of impulsivity and compulsivity.

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Das, Prasun, Raj Saha, Srijak Bhattacharyya, Swadha Priya Basu, and Debopriya Das. "Diagnostic accuracy of transabdominal ultrasound in respect to transvaginal ultrasound in diagnosing ectopic pregnancy in a tertiary care hospital of Kolkata taking histopathology as gold standard: a prospective study." International Journal of Research in Medical Sciences 9, no. 7 (June 25, 2021): 1965. http://dx.doi.org/10.18203/2320-6012.ijrms20212517.

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Background: Ectopic pregnancy (EP) represents an important cause of acute pelvic pain in women of reproductive age. Initial evaluation consists of appropriate history and clinical examination followed by pelvic ultrasonography (US) and hormonal assays. Objective of the study was to measure diagnostic accuracy of TAS in respect to TVS in detecting ectopic pregnancy.Methods: This prospective cross sectional study was done for 1 year duration in Nilratan Sircar Medical College and Hospital, Kolkata. 50 patients with suspected ectopic pregnancy were transferred from Gynae emergency ward and trans-abdominal, transvaginal ultrasound were subsequently performed on each. The results were corroborated with histopathology reports..Results: Diagnostic parameters of TAS in respect to HPE:sensitivity 75.5, specificity-80,PPV-97.1, NPV-26.6 (all in percentages). Diagnostic parameters of TVS in respect to HPE:sensitivity 86.6, specificity-80, PPV-97.5, NPV-40 (all in percentages).Conclusions: Sonography by transvaginal route stood way ahead of trans abdominal scan in terms of all diagnostic parameters to correctly evaluate ectopic pregnancy.

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Stoyanov, Drozdstoj St. "Trans-diagnostic Validation in Neuro-psychiatry: Towards Biological Signatures of Disease." Current Topics in Medicinal Chemistry 20, no. 7 (April 23, 2020): 517. http://dx.doi.org/10.2174/156802662007200316142830.

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Dunkley, Cara R., Yana Svatko, and Lori A. Brotto. "Eating Disorders and Sexual Function Reviewed: A Trans-diagnostic, Dimensional Perspective." Current Sexual Health Reports 12, no. 1 (January 18, 2020): 1–14. http://dx.doi.org/10.1007/s11930-020-00236-w.

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Krueger, Robert F. "Empirical Psychopathology Classification and the Importance of Trans-Diagnostic Dimensional Factors." Journal of the American Academy of Child & Adolescent Psychiatry 57, no. 6 (June 2018): 366–67. http://dx.doi.org/10.1016/j.jaac.2018.03.007.

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Economou, Marina, and Helen Lazaratou. "A trans-diagnostic approach to psychosis, psychiatric medication nomenclature and stigma." European Archives of Psychiatry and Clinical Neuroscience 267, no. 4 (January 10, 2017): 363–64. http://dx.doi.org/10.1007/s00406-016-0763-9.

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Irfan, Muhammad, Abdul Rasheed Qureshi, Zeeshan Ashraf, Muhammad Amjad Ramzan, Tehmina Naeem, and Huma Bilal. "Diagnostic efficacy and suitability of trans-thoracic ultrasonography for pleural fluid detection – The future non-invasive gold-standard?" Journal of Fatima Jinnah Medical University 13, no. 4 (January 15, 2020): 184–90. http://dx.doi.org/10.37018/jfjmu.558.

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ABSTRACT Background: Conventionally Pleural effusions are suspected by history of pleuritis, evaluated by physical signs and multiple view radiography. Trans-thoracic pleural aspiration is done and aspirated pleural fluid is considered the gold-standard for pleural effusion. Chest sonography has the advantage of having high diagnostic efficacy over radiography for the detection of pleural effusion. Furthermore, ultrasonography is free from radiation hazards, inexpensive, readily available and feasible for use in ICU, pregnant and pediatric patients. This study aims to explore the diagnostic accuracy of trans-thoracic ultrasonography for pleural fluid detection, which is free of such disadvantages. The objective is to determine the diagnostic efficacy of trans-thoracic ultrasound for detecting pleural effusion and also to assess its suitability for being a non-invasive gold-standard. Subject and Methods: This retrospective study of 4597 cases was conducted at pulmonology OPD-Gulab Devi Teaching Hospital, Lahore from November 2016 to July 2018. Adult patients with clinical features suggesting pleural effusions were included while those where no suspicion of pleural effusion, patients < 14 years and pregnant ladies were excluded. Patients were subjected to chest x-ray PA and Lateral views and chest ultrasonography was done by a senior qualified radiologist in OPD. Ultrasound-guided pleural aspiration was done in OPD & fluid was sent for analysis. At least 10ml aspirated fluid was considered as diagnostic for pleural effusion. Patient files containing history, physical examination, x-ray reports, ultrasound reports, pleural aspiration notes and informed consent were retrieved, reviewed and findings were recorded in the preformed proforma. Results were tabulated and conclusion was drawn by statistical analysis. Results: Out of 4597 cases, 4498 pleural effusion were manifested on CXR and only 2547(56.62%) pleural effusions were proved by ultrasound while 2050 (45.57%) cases were reported as no Pleural effusion. Chest sonography demonstrated sensitivity, specificity, PPV, NPV and diagnostic accuracy 100 % each. Conclusions: Trans-thoracic ultrasonography revealed an excellent efficacy that is why it can be considered as non-invasive gold standard for the detection of pleural effusion.

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Townsend, Rich. "Trans-Photospheric Wave Leakage in Be Stars." International Astronomical Union Colloquium 175 (2000): 288–91. http://dx.doi.org/10.1017/s0252921100056037.

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AbstractThe phenomenon of trans-photospheric wave leakage in stars undergoing non-radial pulsation is investigated, with an emphasis on its significance for Be stars. It is demonstrated that a symmetry breaking in line-profile variability may be used as a diagnostic for such wave leakage in these stars.

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Slagstad, Ketil. "Society as Cause and Cure: The Norms of Transgender Social Medicine." Culture, Medicine, and Psychiatry 45, no. 3 (June 22, 2021): 456–78. http://dx.doi.org/10.1007/s11013-021-09727-4.

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AbstractThis article analyzes how trans health was negotiated on the margins of psychiatry from the late 1970s and early 1980s. In this period, a new model of medical transition was established for trans people in Norway. Psychiatrists and other medical doctors as well as psychologists and social workers with a special interest and training in social medicine created a new diagnostic and therapeutic regime in which the social aspects of transitioning took center stage. The article situates this regime in a long Norwegian tradition of social medicine, including the important political role of social medicine in the creation of the postwar welfare state and its scope of addressing and changing the societal structures involved in disease. By using archival material, medical records and oral history interviews with former patients and health professionals, I demonstrate how social aspects not only underpinned diagnostic evaluations but were an integral component of the entire therapeutic regime. Sex reassignment became an integrative way of imagining and practicing psychiatry as social medicine. The article specifically unpacks the social element of these diagnostic and therapeutic approaches in trans medicine. Because the locus of intervention and treatment remained the individual, an approach with subversive potential ended up reproducing the norms that caused illness in the first place: “the social” became a conformist tool to help the patient integrate, adjust to and transform the pathology-producing forces of society.

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Hare-Duke, Laurie, Ashleigh Charles, Mike Slade, Stefan Rennick-Egglestone, Ada Dys, and Daan Bijdevaate. "Systematic review and citation content analysis of the CHIME framework for mental health recovery processes: recommendations for developing influential conceptual frameworks." Journal of Recovery in Mental Health 6, no. 1 (January 6, 2023): 38–44. http://dx.doi.org/10.33137/jrmh.v6i1.38556.

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Objectives To identify design features of the CHIME conceptual framework of mental health recovery which are associated with high rates of citation. Research Design and Methods Systematic review of all citations of the Connectedness, Hope, Identity, Meaning, and Empowerment (CHIME) framework of mental health recovery. Papers citing CHIME were screened and extracted from three citation databases. Citation content analysis was used to investigate associations between nine CHIME design features. Citations were investigated across six forms of visibility: all citations; Anglophone vs non-Anglophone; academic vs non-academic; academic discipline; professional group; and clinical population. Results There were 915 eligible documents identified. Six CHIME framework design features met predefined thresholds for high levels of influence: (i) using a systematic review methodology for development, (ii) adopting a memorable acronym, (iii) having disaggregable components, and being unaligned to a (iv) particular discipline (i.e., transdisciplinary), (v) professional group, or (vi) diagnostic population. Documents from Anglophone countries were more likely to cite CHIME with reference to trans-professional (χ2=3.96, df=1, p=0.05) and ethnicity sub-group analysis (p=0.039) design features than non-Anglophone documents. Non-academic documents were more likely to cite the acronym design feature than academic papers (χ2=5.73, df=1, p=0.01). Public Health-related publications were more likely to cite CHIME within a trans-diagnostic framework (χ2=16.39, df=1, p<0.001) than other disciplines. Conclusions The influence and impact of conceptual frameworks for recovery are increased when the framework is underpinned by a systematic review, includes disaggregable components which can be summarized using a memorable acronym, and when the framework is transdisciplinary, trans-professional, and trans-diagnostic.

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Miller, Brian J., Sneha Sareddy, Peter B. Rosenquist, and William V. McCall. "Pupillary light reflex markers of suicide risk in a trans-diagnostic sample." Schizophrenia Research 235 (September 2021): 1–2. http://dx.doi.org/10.1016/j.schres.2021.06.027.

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Rajjoub, Salam, William E. Noble, Henry Kettler, Robert B. Altmeyer, Jeffrey S. Shultz, Lee Weisberger, Robert J. Fanning, and Catherine C. Coleman. "CO2 EMBOLISM DUE TO DIAGNOSTIC LAPAROSCOPY DOCUMENTED BY TRANS-ESOPHAGEAL ECHOCARDIOGRAPHY (TEE)." Southern Medical Journal 89, Supplement (October 1996): S18. http://dx.doi.org/10.1097/00007611-199610001-00019.

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Chamberlain, Samuel R., and Jon E. Grant. "Selective role for the COMT polymorphism in a trans-diagnostic compulsivity phenotype." Psychological Medicine 48, no. 15 (August 24, 2018): 2626–27. http://dx.doi.org/10.1017/s0033291718002180.

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AbstractBackgroundImpulsivity and compulsivity are central to understanding a range of psychiatric disorders but also to understanding the spectrum of normative human behavior. It was recently shown that separable latent phenotypes of impulsivity and compulsivity could be fractionated. The possible genetic contributions to these latent phenotypes have yet to be elicited. The catechol-o-methyl transferase (COMT) Val158Met polymorphism (rs4680) regulates cortical dopamine degradation and is a key area of interest in this context.MethodsCOMT Val158Met polymorphism status was obtained from a random subset (n = 258) of young adults from an established cohort, for whom latent phenotype scores were previously reported. Differences in latent phenotype scores were explored between COMT groups using analysis of variance (ANOVA) and post-hoc t tests.ResultsThe Val-Val subgroup exhibited significantly elevated compulsivity scores compared to both other groups. Impulsivity scores did not differ significantly as a function of COMT Val158Met polymorphism status.ConclusionsThese results suggest that the COMT polymorphism, and by implication cortical dopamine degradation, influences the expression of a trans-diagnostic compulsivity phenotype, even accounting for possible confounding effects of impulsivity.

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Faravelli, C., S. Gorini Amedei, F. Rotella, L. Faravelli, A. Palla, G. Consoli, V. Ricca, et al. "Childhood traumata, Dexamethasone Suppression Test and psychiatric symptoms: a trans-diagnostic approach." Psychological Medicine 40, no. 12 (February 5, 2010): 2037–48. http://dx.doi.org/10.1017/s0033291710000115.

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BackgroundChildhood traumatic events and functional abnormalities of the hypothalamus–pituitary–adrenal (HPA) axis have been widely reported in psychiatric patients, although neither is specific for any diagnosis. Among the limited number of studies that have evaluated these topics, none has adopted a trans-diagnostic approach. The aim of the present research is to explore the relationship between childhood stressors, HPA axis function and psychiatric symptoms, independent of the diagnosis.MethodA total of 93 moderate to severely ill psychiatric out-patients of Florence and Pisa University Psychiatric Units and 33 healthy control subjects were recruited. The assessment consisted of salivary cortisol pre- and post-low dose (0.5 mg) Dexamethasone, early and recent life events, 121 psychiatric symptoms independent of diagnosis, SCID, BPRS.ResultsIn total, 33.5% of patients were Dexamethasone Suppression Test (DST) non-suppressors, compared with 6.1% of controls (p=0.001). Among patients, non-suppression was associated with particular symptoms (i.e. depressive and psychotic), but not to any specific diagnosis. Early stressful life events were significantly associated with higher salivary cortisol levels, with DST non-suppression and with approximately the same subset of symptoms. A recent stressful event seemed to be associated to the HPA response only in those subjects who were exposed to early traumata.ConclusionsOur report suggests a relationship between life stress, HPA axis and psychopathology. A cluster of specific psychiatric symptoms seems to be stress related. Moreover, it seems that an abnormal HPA response is possibly triggered by an excessive pressure in vulnerable individuals.

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Preobrazhensky, Victor N. "Organization-Methodic Problems of Established Medical-Diagnostic Standards in Trans-Border Situations." Prehospital and Disaster Medicine 18, S1 (March 2003): S11. http://dx.doi.org/10.1017/s1049023x00057721.

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Mandali, Alekhya, Claire Gillan, and Valerie Voon. "27 The coexistence of social withdrawal and impulsivity: a trans-diagnostic approach." Journal of Neurology, Neurosurgery & Psychiatry 91, no. 8 (July 20, 2020): e19.1-e19. http://dx.doi.org/10.1136/jnnp-2020-bnpa.44.

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IntroductionSocial anxiety disorder or phobia (SAD) is a debilitating condition, where an individual experiences overwhelming fear to situations involving social interactions. Prototypically, SAD presents as shy, submissive, inhibited, and risk- aversive behaviours. Contrastingly, an atypical sub-group show impulsive, aggressive, novelty-seeking behaviours along with severe substance abuse problems. In scenarios, where there is co-existence of polar opposite symptoms, trans-diagnostic approaches extrapolate the characteristics of a disorder as a continuum rather than a categorical one. Data-driven computational models such as drift diffusion model utilize behavioural measures and extract potential markers that reflect the activity of specific brain networks. Here, we aim to analyse and correlate the psychological traits with computational estimates of behaviour during risk-taking and value based decision making.MethodsWe used the data from 1400 participants who completed the 2 stage sequential learning task. We focused on the second stage of the task, where the reward probabilities of the choices are stochastic. The computational measures were estimated for two scenarios i.e. when the participants made 1) accurate choices and 2) risky choices (the choice with maximum variance in reward probability was labelled as risky). This computation was performed for all the trials across all the participants. We then used choice–(risky vs non-risky or correct vs incorrect) and response time as inputs to the hierarchical drift diffusion model to extract threshold (a), drift rate (v) and response bias (z) parameters. The computational parameters were then correlated with the 3 psychological factors that span the compulsive, anxiety- depression and the social withdrawal spectrum.ResultsThe computational parameters from both accuracy and risk taking scenarios of the sequential learning task were correlated with the 3 factors. While controlling for IQ and age, we found a generalized correlation which is significant between the threshold parameter(‘a’) and social withdrawal, with the former estimate being negatively correlated (Accuracy: |r| = -0.078, p=0.003; Risk: |r| = -0.075, p=0.005) with the latter. This relation was not observed with regard to anxiety-depression and compulsive traits.ConclusionsWe show that individuals with higher social withdrawal levels are impulsive as they accumulate less evidence while making a choice. This behaviour holds irrespective of the choice being chosen is an optimal or a risky one. Critically, we show how a trans-diagnostic approach of integrating computational model and psychological questionnaires can reveal the existence of psychological traits as a continuum.

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Attard, G., J. S. de Bono, J. Clark, and C. S. Cooper. "Studies of TMPRSS2-ERG Gene Fusions in Diagnostic Trans-Rectal Prostate Biopsies." Clinical Cancer Research 16, no. 4 (February 9, 2010): 1340. http://dx.doi.org/10.1158/1078-0432.ccr-09-2253.

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Golwala, Harsh, and Joaquin E. Cigarroa. "Heparin for diagnostic trans-radial catheterization: Can we have some randomized data?" Catheterization and Cardiovascular Interventions 92, no. 5 (November 1, 2018): 860–61. http://dx.doi.org/10.1002/ccd.27937.

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Cosci, Fiammetta, and Giovanni A. Fava. "The clinical inadequacy of the DSM-5 classification of somatic symptom and related disorders: an alternative trans-diagnostic model." CNS Spectrums 21, no. 4 (December 28, 2015): 310–17. http://dx.doi.org/10.1017/s1092852915000760.

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The Diagnostic and Statistical of Mental Disorders, Fifth Edition (DSM-5) somatic symptom and related disorders chapter has a limited clinical utility. In addition to the problems that the single diagnostic rubrics and the deletion of the diagnosis of hypochondriasis entail, there are 2 major ambiguities: (1) the use of the term “somatic symptoms” reflects an ill-defined concept of somatization and (2) abnormal illness behavior is included in all diagnostic rubrics, but it is never conceptually defined. In the present review of the literature, we will attempt to approach the clinical issue from a different angle, by introducing the trans-diagnostic viewpoint of illness behavior and propose an alternative clinimetric classification system, based on the Diagnostic Criteria for Psychosomatic Research.

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Latham, J. R. "Axiomatic: Constituting ‘transexuality’ and trans sexualities in medicine." Sexualities 22, no. 1-2 (January 30, 2018): 13–30. http://dx.doi.org/10.1177/1363460717740258.

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This article argues that medicine misunderstands the necessarily complex ways trans people experience sexuality. Despite revisions to treatment guidelines and diagnostic descriptions, transgender medicine continues to be based on a paradigmatic narrative of ‘being born in the wrong body’. This narrative performatively reproduces sex, gender and ‘gender dysphoria’ as static, predetermined and independent of medical encounters. It also constructs trans sexualities as limited by and dependent on gender/genital ‘alignment’, which necessarily neglects many trans people’s sexual lives. By mobilising critiques of singularity from science and technology studies (STS), which emphasise how discourses and practices produce both what is knowable and materially possible, this article explores how medicine understands and constitutes ‘transexuality’ as a singular phenomenon that limits trans sexualities. By analysing contemporary medical guidebooks alongside the foundational text of trans medical treatment – Harry Benjamin’s (1999 [1966]) The Transsexual Phenomenon – I argue that medicine constitutes transexuality and understands trans sexualities via four axioms: 1) Transexuality is a disjuncture between mind and body; 2) Transexuality is hating having the wrong genitals; 3) Transexuality is painful and debilitating; and 4) Transexuality is resolvable with hormonal and surgical body modifications. In so doing, medicine flattens out the complexities of trans people’s experiences of gender and sexuality, and simultaneously disavows many trans people’s sexual lives.

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Fan, Siyan, Danielle C. Cath, Ysbrand D. van der Werf, Stella de Wit, Dick J. Veltman, and Odile A. van den Heuvel. "Trans-diagnostic comparison of response inhibition in Tourette’s disorder and obsessive-compulsive disorder." World Journal of Biological Psychiatry 19, no. 7 (July 25, 2017): 527–37. http://dx.doi.org/10.1080/15622975.2017.1347711.

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Rogers, Denise C., Antonia J. Dittner, Katharine A. Rimes, and Trudie Chalder. "Fatigue in an adult attention deficit hyperactivity disorder population: A trans-diagnostic approach." British Journal of Clinical Psychology 56, no. 1 (December 5, 2016): 33–52. http://dx.doi.org/10.1111/bjc.12119.

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Jabri, H., W. Elkhattabi, Z. Berrada, K. Rhafoune, H. Afif, A. Aichane, and Z. Bouayad. "Place de la ponction biopsie trans-pariétale dans le diagnostic du carcinome bronchogénique." Revue des Maladies Respiratoires 29 (January 2012): A156. http://dx.doi.org/10.1016/j.rmr.2011.10.752.

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Gelas, T., R. Dubois, F. Lardellier-Reynaud, C. Rivet, L. Viremouneix, and A. Lachaux. "SFCP CO-72 - Cholangiographie trans-vésiculaire laparoscopique pour le diagnostic des cholestases néonatales." Archives de Pédiatrie 21, no. 5 (May 2014): 450. http://dx.doi.org/10.1016/s0929-693x(14)71710-5.

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La Fianza, Alfredo, Maurizio Bonfichi, Maria Sole Prevedoni Gorone, Anna Gallotti, and Lorella Torretta. "Unusual abdominal findings of all-trans-retinoic acid syndrome: role of diagnostic imaging." Clinical Imaging 31, no. 4 (July 2007): 276–78. http://dx.doi.org/10.1016/j.clinimag.2006.11.004.

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Sayed, Suzan Salama, Gamal M. Agmy, Azza Farag Said, and Ahmad Hussein Kasem. "Diagnostic performance of trans-thoracic sonography in patients of pneumonia and pulmonary embolism." Egyptian Journal of Chest Diseases and Tuberculosis 65, no. 3 (July 2016): 621–28. http://dx.doi.org/10.1016/j.ejcdt.2016.01.008.

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Djordjevic, Filip, Dejan Dubovina, Marija Bubalo, Rasa Radosavljevic, and Zoran Bukumiric. "Gingival biotype - comparative analysis of different evaluation methods." Vojnosanitetski pregled, no. 00 (2021): 56. http://dx.doi.org/10.2298/vsp210318056d.

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Background/Aim. Gingival biotype can have a significant impact on the outcome of the periodontal therapeutic procedures and on the predictability of their aesthetic outcome. There is a strong correlation between the types of biotype and the potential gingival recession after restorative, periodontal and implant surgical procedures. Therefore, accurate identification of gingival biotypes, before initiating these procedures, is one of the significant predictive factors for their success. The aim of this study was to evaluate reliability of accurate gingival biotype determination with the use of visual method, periodontal and trans-gingival probing compared to the direct measurement method. Methods. This prospective study involved 33 patients indicated for the apical root resection in the intercanine sector of the upper jaw. Gingival biotype identification was performed in all of the patients using the following techniques: 1) visual method; 2) periodontal probe technique; 3) trans-gingival probing; 4) direct measurement after flap elevation was performed. Statistical analysis of the obtained data was performed to assess the diagnostic accuracy of the visual method, periodontal probing method and trans-gingival probing method, in relation to the direct measurement method, used as a gold standard, to discriminate the gingival thickness biotype (thin versus thick). Results. The overall accuracy of the tested diagnostic procedures, compared to direct gingival biotype measurement, was: 66.7% for visual method; 78.8% for periodontal probing; and 97.0% for trans-mucosal probing. Conclusion. Periodontal probing method can be recommended for gingival biotype determination as a routine method, due to the fact that its sensitivity and overall accuracy is higher compared to the visual method. The trans-gingival method, in terms of sensitivity and comprehensive accuracy, almost completely coincides with the direct method, but it is more invasive compared to periodontal probing method and it has to be conducted in local anesthesia.

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Sánchez, José Luis Muñoz, Vladimir Jorge Carrasco, and Pedro Zorrilla Ribot. "Fenton Syndrome: Diagnosis and Treatment with 3D-Printed Models. An Unusual Case Report." Revista Iberoamericana de Cirugía de la Mano 49, no. 01 (May 2021): 066–73. http://dx.doi.org/10.1055/s-0041-1730000.

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AbstractScaphocapitate syndrome, also called Fenton syndrome, is a rare, complex condition. Since it is often missed on initial evaluation, it is a diagnostic challenge. A high index of suspicion is required for early surgical treatment, avoiding future palliative surgery or sequelae. Cutting-edge diagnostic technologies, including three-dimensional printed models, are becoming essential tools, enabling the treatment of complex trans-scaphocapitate fracture-dislocations using open reduction and internal fixation with screws, with excellent outcomes at a 12-month follow-up period.

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Djokic, Milomir, Milomir Milanovic, Vesna Begovic, Andjelka Ristic-Andjelkov, and Branka Tomanovic. "Infective endocarditis of a rare etiology: Serratia marcescens." Vojnosanitetski pregled 61, no. 6 (2004): 689–94. http://dx.doi.org/10.2298/vsp0406689d.

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Infective endocarditis (IE) is a unique diagnostic and therapeutic challenge. It is a severe disease, fatal before penicillin discovery. Atypical presentations frequently led to delayed diagnosis and poor outcome. There was little information about the natural history of the vegetations during medical treatment or the relation of morphologic changes in vegetation to late complications. Application of a new diagnostic criteria and echocardiography, increased the number of definite diagnosis. Trans-thoracic and trans-esophageal echocardiography had an established role in the management of patients with IE. The evolution of vegetation size, its mobility, and consistency, the extent of the disease, and the severity of valvular regurgutation were related to late complications. With therapeutic options including modern antibiotic treatment and early surgical intervention IE turned out to be a curable disease. Reduction in mortality also depended on prevention. Antibiotic prophylaxis of IE was important, but low mortality was also the result of early treatment, especially in the event of early recognition of symptoms and signs of the disease.

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Cucci, Costanza, Marcello Picollo, and Muriel Vervat. "Trans-illumination and trans-irradiation with digital cameras: Potentials and limits of two imaging techniques used for the diagnostic investigation of paintings." Journal of Cultural Heritage 13, no. 1 (January 2012): 83–88. http://dx.doi.org/10.1016/j.culher.2011.07.002.

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Biswas, Dr Siddhartha, Dr Rama Saha, Dr Prof Jaydip Deb, and Dr Prothoma Dey. "Evaluation of trans thoracic invasive diagnostic procedures in 50 adult patients of mediastinal diseases." International Journal of Medical Research and Review 7, no. 4 (August 31, 2019): 324–31. http://dx.doi.org/10.17511/ijmrr.2019.i04.11.

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Buchovsky, A. S., O. Campetella, G. Russomando, L. Franco, R. Oddone, N. Candia, A. Luquetti, S. M. Gonzalez Cappa, and M. S. Leguizamon. "trans-Sialidase Inhibition Assay, a Highly Sensitive and Specific Diagnostic Test for Chagas' Disease." Clinical Diagnostic Laboratory Immunology 8, no. 1 (January 1, 2001): 187–89. http://dx.doi.org/10.1128/cdli.8.1.187-189.2001.

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ABSTRACT For the diagnosis of Chagas' disease, thetrans-sialidase inhibition assay was able to resolve the results for samples with borderline results, to detect as positive 60% of samples that were negative by conventional serology, and to discriminate idiopathic from chagasic megaviscera or cardiopathy. No cross-reaction with sera from patients with other diseases was observed.

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Dakanalis, Antonios, C. Alix Timko, Massimo Clerici, M. Assunta Zanetti, and Giuseppe Riva. "Comprehensive examination of the trans-diagnostic cognitive behavioral model of eating disorders in males." Eating Behaviors 15, no. 1 (January 2014): 63–67. http://dx.doi.org/10.1016/j.eatbeh.2013.10.003.

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