Dissertations / Theses on the topic 'Traitement d’images optiques'
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Hennequin, Christophe. "Etude et réalisation d’un calculateur temps réel embarqué pour la détection de petits objets dans des séquences d’images multi-échelles." Dijon, 2008. http://www.theses.fr/2008DIJOS015.
Full textThis doctoral thesis is part of a research project of the French-German Research Institute of Saint-Louis (ISL) which has been set up to equip artillery projectiles with an on-board image acquisition and processing system. The study focused on real-time target detection in aerial image sequences, considering the imposed restrictions of low quality images, reduced target size and variable acquisition altitude. In view of the unsatisfactory efficiency of the reference algorithms to rapidly detect small objects in our image sequences, an advanced detection algorithm combining statistical methods with morphological filtering has been developed. After analysing in detail the detector’s behaviour and validating its performance, an algorithm/architecture adequacy approach is used for implementing a compatible real-time processing for embedded systems. Finally, the design of a specific and highly parallel architecture allowed to realize a prototype calculator with a programmable component
Coquand, Mathieu. "Méthode de rétrovisée pour la caractérisation de surfaces optiques dans une installation solaire à concentration." Thesis, Perpignan, 2018. http://www.theses.fr/2018PERP0001/document.
Full textConcentrated solar power is a promising way for renewable energy production. Optical efficiency of the mirrors is one of the key factors influencing a power plant performance. Methods which allow the operator to adjust all the heliostat of a plant quickly, in addition of calibration and tracking, are essential for the rise of the technology. The work presented in this thesis is the study of a “backward-gazing” method consisting in placing four cameras near the receiver simultaneously recording brightness images of the sun reflected by the heliostat. The optical errors of the mirrors are retrieved from these four images and the knowledge of the one dimension sun radiance profile.The first step of the study consists in the theoretical description of the method. Then numerical simulations are performed to estimate the general accuracy and the limits of the backward-gazing method. In a third phase, experimental tests have been fulfilled at Themis solar power plant. Finally, ideas of improvement are proposed based on the experiments performed
Madec, Morgan. "Conception, simulation et réalisation d’un processeur optoélectronique pour la reconstruction d’images médicales." Université Louis Pasteur (Strasbourg) (1971-2008), 2006. https://publication-theses.unistra.fr/public/theses_doctorat/2006/MADEC_Morgan_2006.pdf.
Full textOptical processing can be used to speed up some algorithms of image reconstruction from tomodensitometric data provided by volume exploration systems. This may be of high interest in order to meet the needs of future assisted therapy systems. Two systems are described in this document, corresponding to the two main steps of the above mentioned algorithms: a filtering processor and a backprojection processor. They are first considered under a material point of view. Whatever function it may compute, an optical processor is made up of light sources, displays and cameras. Present state-of-the-art devices highlight a weakness in display performances. Special attention has been focused on ferroelectric liquid crystal spatial light modulators (modelling, simulations, and characterizations of commercial solutions). The potential of optical architectures is compared with electronic solutions, considering computation power and processed image quality. This study has been carried out for both systems first in simulation, with a reliable model of the architecture, and then with an experimental prototype. The optical filtering processor does not give accurate results: the signal to noise ratio on the reconstructed image is about 20 dB in simulation (the model used does not take into account the majority of geometrical distortions) and experimental measurements show strong limitation, especially when considering the problem of image formation with coherent lighting (speckle). On the other hand, results obtained with the optical backprojection processor are most encouraging. The model, more complete and accurate than the filtering processor, as well as the simulations, shows that processed image quality can be virtually equivalent to the one obtained by digital means (signal to noise ratio is over 50 dB) with two order of magnitude speed-up. Results obtained with the experimental prototype are in accordance with simulations and confirm the potential held by the architecture. As an extension, a hybrid processor involving the backprojection processor for the computation of more complex reconstruction algorithms, e. G. ASSR for helical CT-scan, is proposed in the last part of the document
Desrues, Mathilde. "Surveillance opérationnelle de mouvements gravitaires par séries temporelles d'images." Thesis, Strasbourg, 2021. http://www.theses.fr/2021STRAH002.
Full textUnderstanding the dynamics and the behavior of gravitational slope movements is essential to anticipate catastrophic failures and thus to protect lives and infrastructures. Several geodetic techniques already bring some information on the displacement / deformation fields of the unstable slopes. These techniques allow the analysis of the geometrical properties of the moving masses and of the mechanical behavior of the slopes. By combining time series of passive terrestrial imagery and these classical techniques, the amount of collected information is densified and spatially distributed. Digital passive sensors are increasingly used for the detection and the monitoring of gravitational motion. They provide both qualitative information, such as the detection of surface changes, and a quantitative characterization, such as the quantification of the soil displacement by correlation techniques. Our approach consists in analyzing time series of terrestrial images from either a single fixed camera or pair-wise cameras, the latter to obtain redundant and additional information. The time series are processed to detect the areas in which the Kinematic behavior is homogeneous. The slope properties, such as the sliding volume and the thickness of the moving mass, are part of the analysis results to obtain an overview which is as complete as possible. This work is presented around the analysis of four landslides located in the French Alps. It is part of a CIFRE/ANRT agreement between the SAGE Society - Société Alpine de Géotechnique (Gières, France) and the IPGS - Institut de Physique du Globe de Strasbourg / CNRS UMR 7516 (Strasbourg, France)
Maaloul, Boutheina. "Des algorithmes de détection d'accidents routiers par vidéo surveillance." Thesis, Valenciennes, 2018. http://www.theses.fr/2018VALE0028.
Full textAutomatic video surveillance systems have been developed to detect and analyze abnormal behavior or situation of risk in many fields reducing human monitoring of activities captured by cameras (security surveillance, abnormal behavior detection, etc.). One of the applications of video surveillance is the traffic monitoring. Analyzing the motion in roads aims to detect abnormal traffic behavior and sudden events, especially in case of Emergency and Disaster Management (EDM). Road accidents can cause serious injuries affecting mostly the head and the brain, leading to lifelong disabilities and even death; each additional rescue minute can mean the difference between life and death as revealed by the golden Hour[Lerner et al., 2001]. Therefore, providing a rapid assistance for injuries is mandatory. Moreover, if not addressed promptly, accidents may cause traffic jams, eventually leading to more accidents, and even greater loss of lives and properties. Many cities in France are equipped with video surveillance cameras installed on different roads and highways. Traffic monitoring is done by human operators to visualize the congestion of a road or to measure the flow of the traffic. The video stream of this existing network of cameras is delivered unprocessed to the traffic management center. Thus, there are no video storage of accident scenes. In addition, there is no associated technology for a rapid emergency management. Therefore, it is important to design a system able toorganizean effective emergency response. This response should be based, firstly on an automatic detection by video analysis, then, on a rapid notification allowing the optimization of the emergency intervention itinerary without affecting the traffic state. Our work resolves the first part of the emergency response.The objectives of this thesis are firstly the identification of accident scenarios and the collection of data related to road accident; next, the design and the development of video processing algorithms for the automatic detection of accidents in highways. The developed solutions will use the existing fixed cameras, so as not to require significant investments in infrastructure. The core of the proposed approaches will focus on the use of the dense Optical Flow (OF) algorithm [Farnebäck, 2003] and heuristic computations for features extraction and accident recognition. The purpose of the dense OF is to estimate the motion of each pixel in a region of interest (ROI) between two given frames. At the output of the dense OF, a dense features could be extracted which is more performant than features extracted at some points. Defining thresholds for accident detection in various environment is very challenging. Therefore, studying the motion at a global scale in the image, allows defining a dynamic thresholds for accident detection using statistic computations. The proposed solution is sufficient and robust to noise and light changing
Yildizoglu, Romain. "Etude de relaxations en traitement d'images. Application à la segmentation et autres problèmes multi-étiquettes." Thesis, Bordeaux, 2014. http://www.theses.fr/2014BORD0129/document.
Full textIn this thesis we study different relaxations of non-convex functionals that can be found in image processing. Some problems, such as image segmentation, can indeed be written as the minimization of a functional. The minimizer of the functional represents the segmentation. Different methods have been proposed in order to find local or global minima of the non-convex functional of the two-phase piecewise constant Mumford-Shah model. With a convex relaxation of this model we can find a global minimum of the nonconvex functional. We present and compare some of these methods and we propose a new model with a narrow band. This model finds local minima while using robust convex optimization algorithms. Then a convex relaxation of a two-phase segmentation model is built that compares two given histograms with those of the two segmented regions. We also study some relaxations of high-dimension multi-label problems such as optical flow computation. A convex relaxation with a new algorithm is proposed. The algorithm is iterative with exact projections. A new algorithm is given for a relaxationthat is convex in each variable but that is not convex globally. We study the problem of constructing a solution of the original non-convex problem with a solution of the relaxed problem. We compare existing methods with new ones
Ferraris, Vinicius. "Détection de changement par fusion d'images de télédétection de résolutions et modalités différentes." Thesis, Toulouse, INPT, 2018. http://oatao.univ-toulouse.fr/24107/1/Ferraris_Vinicius.pdf.
Full textAlston, Laure. "Spectroscopie de fluorescence et imagerie optique pour l'assistance à la résection de gliomes : conception et caractérisation de systèmes de mesure et modèles de traitement des données associées, sur fantômes et au bloc opératoire." Thesis, Lyon, 2017. http://www.theses.fr/2017LYSE1295/document.
Full textGliomas are infiltrative tumors of the brain which are yet hardly curable, notably because of the difficulty to precisely delimitate their margins during surgery. Intraoperative 5-ALA induced protoporphyrin IX (PpIX) fluorescence microscopy has shown its relevance to assist neurosurgeons but lacks sensitivity. In this thesis, we perform a spectroscopic clinical trial on 10 patients with the assumption that collected fluorescence is a linear combination of the contribution of two states of PpIX which proportions vary with the density of tumor cells. This work starts with the development of the intraoperative, portable and real time fluorescence spectroscopic device that provides multi-wavelength excitation. Then, we show its use on PpIX phantoms with tissues mimicking properties. This first enables to obtain a reference emitted spectrum for each state apart and then permits the development of a fitting model to adjust any emitted spectrum as a linear combination of the references in the spectral band 608-637 nm. Next, we present the steps led to get approvals for the clinical trial, especially the risk analysis. In vivo data analysis is then presented, showing that we detect fluorescence where current microscopes cannot, which could exhibit a change in PpIX state from glioma center to its margins. Besides, the relevance of multi-wavelength excitation is highlighted as the correlation between the three measured spectra of a same sample decreases with the density of tumor cells. Finally, the complementary need to intraoperatively identify cerebral functional areas is tackled with optical measurements as a perspective and other properties of PpIX on phantoms are also raised
Chen, Xu. "New formulation of optical flow for turbulence estimation." Thesis, Ecully, Ecole centrale de Lyon, 2015. http://www.theses.fr/2015ECDL0025/document.
Full textThe method of optical flow is a powerful tool for motion estimation. It is able to extract the dense velocity field from image sequence. In this study, we employ this method to retrieve precisely the incompressible turbulent motions. For 2D turbulence estimation, it consists in minimizing an objective function constituted by an observation term and a regularization one. The observation term is based on the transport equation of a passive scalar field. For non-fully resolved scalar images, we propose to use the mixed model in large eddy simulation (LES) to determine the interaction between large-scale motions and the unresolved ones. The regularization term is based on the continuity equation of 2D incompressible flows. Evaluation of the proposed formulation is done over synthetic and experimental images. In addition, we extend optical flow to three dimensional and multiple scalar databases are generated with direct numerical simulation (DNS) in order to evaluate the performance of optical flow in the 3D context. We propose two formulations differing by the order of the regularizer. Numerical results show that the formulation with second-order regularizer outperforms its first-order counterpart. We also draw special attention to the effect of Schmidt number, which characterizes the ratio between the molecular diffusion of the scalar and the dissipation of the turbulence. Results show that the precision of the estimation increases as the Schmidt number increases. Overall, optical flow has showcased its capability of reconstructing the turbulent flow with excellent accuracy. This method has all the potential and attributes to become an effective flow measurement approach in fluid mechanics community
Mansouri, Abdelkhalek. "Generic heuristics on GPU to superpixel segmentation and application to optical flow estimation." Thesis, Bourgogne Franche-Comté, 2020. http://www.theses.fr/2020UBFCA012.
Full textFinding clusters in point clouds and matching graphs to graphs are recurrent tasks in computer science domain, data analysis, image processing, that are most often modeled as NP-hard optimization problems. With the development and accessibility of cheap multiprocessors, acceleration of the heuristic procedures for these tasks becomes possible and necessary. We propose parallel implantation on GPU (graphics processing unit) system for some generic algorithms applied here to image superpixel segmentation and image optical flow problem. The aim is to provide generic algorithms based on standard decentralized data structures to be easy to improve and customized on many optimization problems and parallel platforms.The proposed parallel algorithm implementations include classical k-means algorithm and application of minimum spanning forest computation for super-pixel segmentation. They include also a parallel local search procedure, and a population-based memetic algorithm applied to optical flow estimation based on superpixel matching. While data operations fully exploit GPU, the memetic algorithm operates like a coalition of processes executed in parallel on the multi-core CPU and requesting GPU resources. Images are point clouds in 3D Euclidean space (space-gray value domain), and are also graphs to which are assigned processor grids. GPU kernels execute parallel transformations under CPU control whose limited role only consists in stopping criteria evaluation or sequencing transformations.The presented contribution contains two main parts. Firstly, we present tools for superpixel segmentation. A parallel implementation of the k-means algorithm is presented with application to 3D data. It is based on a cellular grid subdivision of 3D space that allows closest point findings in constant optimal time for bounded distributions. We present an application of the parallel Boruvka minimum spanning tree algorithm to compute watershed minimum spanning forest. Secondly, based on the generated superpixels and segmentation, we derive parallel optimization procedures for optical flow estimation with edge aware filtering. The method includes construction and improvement heuristics, as winner-take-all and parallel local search, and their embedding into a population-based metaheuristic framework. The algorithms are presented and evaluated in comparison to state-of-the-art algorithms
Awad, Dounia. "Vers un système perceptuel de reconnaissance d'objets." Thesis, La Rochelle, 2014. http://www.theses.fr/2014LAROS017/document.
Full textThe main objective of this thesis is to propose a pipeline for an object recognition algorithm, near to human perception, and at the same time, address the problems of Content Based image retrieval (CBIR) algorithm complexity : query run time and memory allocation. In this context, we propose a filter based on visual attention system to select salient points according to human interests from the interest points extracted by a traditionnal interest points detectors. The test of our approach, using Perreira Da Silva’s system as filter, on VOC 2005 databases, demonstrated that we can maintain approximately the same performance of a object recognition system by selecting only 40% of interest points (extracted by Harris-Laplace and Laplacian), while having an important gain in complexity (40% gain in query-run time and 60% in complexity). Furthermore, we address the problem of high dimensionality of descriptor in object recognition system. We proposed a new hybrid texture descriptor, representing the spatial frequency of some perceptual features extracted by a visual attention system. This descriptor has the advantage of being lower dimension vs. traditional descriptors. Evaluating our descriptor with an object recognition system (interest points detectors are Harris-Laplace & Laplacian) on VOC 2007 databases showed a slightly decrease in the performance (with 5% loss in Average Precision) compared to the original system, based on SIFT descriptor (with 50% complexity gain). In addition, we evaluated our descriptor using a visual attention system as interest point detector, on VOC 2005 databases. The experiment showed a slightly decrease in performance (with 3% loss in performance), meanwhile we reduced drastically the complexity of the system (with 50% gain in run-query time and 70% in complexity)
Dohet-Eraly, Jérôme. "Méthodes de microscopie par holographie numérique interférentielle en couleurs avec un éclairage partiellement cohérent." Doctoral thesis, Universite Libre de Bruxelles, 2017. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/250123.
Full textThe thesis deals with methods and developments in color digital holographic microscopy (DHM), with a partial spatial coherence illumination. The principal drawback of classical optical microscopy is its poor depth of field, which makes difficult the observation of dynamic phenomena in thick samples. On the contrary, DHM provides reconstruction in depth thanks to numeric propagation of the recorded hologram. Another feature of interferometric DHM is the quantitative phase contrast imaging, useful for analyzing transparent objects. Usual DHM is limited to monochromatic case, but multispectral illumination in an appropriate setup leads to color DHM. Color in-flow imaging of particles in DHM is developed in the thesis, with a method for the automatic correction of color balance and permanent defects. It is applied to analyze plankton microorganisms in untreated pond water samples, and provides high quality images, for both optical phase and intensity. Moreover, noise reduction obtained when decreasing the spatial coherence of the illumination in DHM is also investigated in the thesis, with the development of two models that quantitatively assess the noise reduction as a function of both the spatial coherence of the illumination, and the defocus distance of the noise source. Furthermore, differential DHM (DDHM) is also studied in the thesis. As DHM gives the optical phase, DDHM provides differential phases, from which phase is retrieved by integration. However, misalignments and defects give some aberrations, which affect phase quality and hinder refocusing. A specific hologram processing is developed, giving an accurate phase image and enabling holographic reconstruction in depth. Finally, in DHM, a criterion is essential to automatically achieve the refocusing distance of the object. Two refocusing criteria are developed in the thesis, both working independently of the nature of the observed object (amplitude, phase, or both mixed). The first one, monochromatic, is based on amplitude analysis and on a high-pass filtering process. The second one, which gives fast refocusing in multispectral DHM, compares the phase in the Fourier domain among wavelengths. Methods developed in the thesis show the high potential of color DHM with a partial spatial coherence illumination, suggesting a promising future for this technique.
Doctorat en Sciences de l'ingénieur et technologie
info:eu-repo/semantics/nonPublished
Leong-Hoï, Audrey. "Etude des techniques de super-résolution latérale en nanoscopie et développement d'un système interférométrique nano-3D." Thesis, Strasbourg, 2016. http://www.theses.fr/2016STRAD048/document.
Full textThis manuscript presents the study of the lateral super-resolution techniques in optical nanoscopy, which is a new high-resolution imaging method now widely used in biophysics and medical imaging, to observe and measure nanostructures, with the advantages of far field optical imaging, such as a large field of view, visualization and analysis in real time…One of the future challenges of 3D super resolution microscopy is to avoid the use of fluorescent markers. Interferometric microscopy is a 3D label-free imaging technique enabling the detection of nanostructures. To improve the detection capability of this optical system, a first version of a protocol composed of image processing methods was developed and implemented, revealing structures initially unmeasurable. Then, to improve the lateral resolution of the system, a new technique combining interferometry and the principle of the photonic nano-jet has been developed, thus allowing the observation of objects of a size smaller than the diffraction limit of the optical instrument
Neumann, Markus. "Automatic multimodal real-time tracking for image plane alignment in interventional Magnetic Resonance Imaging." Phd thesis, Université de Strasbourg, 2014. http://tel.archives-ouvertes.fr/tel-01038023.
Full textTarafdar, Arundhati. "Wordspotting from multilingual and stylistic documents." Thesis, Tours, 2017. http://www.theses.fr/2017TOUR4022/document.
Full textWord spotting in graphical documents is a very challenging task. To address such scenarios this thesis deals with developing a word spotting system dedicated to geographical documents with Bangla and English (Roman) scripts. In the proposed system, at first, text-graphics layers are separated using filtering, clustering and self-reinforcement through classifier. Additionally, instead of using binary decision we have used probabilistic measurement to represent the text components. Subsequently, in the text layer, character segmentation approach is applied using water-reservoir based method to extract individual character from the document. Then recognition of these isolated characters is done using rotation invariant feature, coupled with SVM classifier. Well recognized characters are then grouped based on their sizes. Initial spotting is started to find a query word among those groups of characters. In case if the system could spot a word partially due to any noise, SIFT is applied to identify missing portion of that partial spotting. Experimental results on Roman and Bangla scripts document images show that the method is feasible to spot a location in text labeled graphical documents. Experiments are done on an annotated dataset which was developed for this work. We have made this annotated dataset available publicly for other researchers
Frugier, Pierre Antoine. "Quantification 3D d’une surface dynamique par lumière structurée en impulsion nanoseconde. Application à la physique des chocs, du millimètre au décimètre." Thesis, Paris 11, 2015. http://www.theses.fr/2015PA112129.
Full textA Structured Light System (SLS) is an efficient means to measure a surface topography, as it features both high accuracy and dense spatial sampling in a strict non-invasive way. For these reasons, it became in the past years a technique of reference. The aim of the PhD is to bring this technique to the field of shock physics. Experiments involving shocks are indeed very specific: they only allow single-shot acquisition of extremely short phenomena occurring under a large range of spatial extensions (from a few mm to decimeters). In order to address these difficulties, we have envisioned the use of a well-known high-speed technique: pulsed laser illumination. The first part of the work deals with the evaluation of the key-parameters that have to be taken into account if one wants to get sharp acquisitions. The extensive study demonstrates that speckle effect and depth of field limitation are of particular importance. In this part, we provide an effective way to smooth speckle in nanosecond regime, leaving 14% of residual contrast. Second part introduces an original projective formulation for object-points reconstruction. This geometric approach is rigorous; it doesn’t involve any weak-perspective assumptions or geometric constraints (like camera-projector crossing of optical axis in object space). From this formulation, a calibration procedure is derived; we demonstrate that calibrating any structured-light system can be done by extending the Direct Linear Transformation (DLT) photogrammetric approach to SLS. Finally, we demonstrate that reconstruction uncertainties can be derived from the proposed model in an a priori manner; the accuracy of the reconstruction depends both on the configuration of the instrument and on the object shape itself. We finally introduce a procedure for optimizing the configuration of the instrument in order to lower the uncertainties for a given object. Since depth of field puts a limitation on the lowest measurable field extension, the third part focuses on extending it through pupil coding. We present an original way of designing phase components, based on criteria and metrics defined in Fourier space. The design of a binary annular phase mask is exhibited theoretically and experimentally. This one tolerates a defocus as high as Ψ≥±40 radians, without the need for image processing. We also demonstrate that masks designed with our method can restore extremely high defoci (Ψ≈±100 radians) after processing, hence extending depth of focus by amounts unseen yet. Finally, the fourth part exhibits experimental measurements obtained with the setup in different high-speed regimes and for different scales. It was embedded on LULI2000 high energy laser facility, and allowed measurements of the deformation and dynamic fragmentation of a sample of carbon. Finally, sub-millimetric deformations measured in ultra-high speed regime, on a cylinder of copper under pyrotechnic solicitation are presented
Vanni, Matthieu P. "Les cartes fonctionnelles dans le cortex visuel du chat : nouvelles stratégies d’évaluation en imagerie optique et mise en évidence de l’organisation anatomo-fonctionnelle." Thèse, 2010. http://hdl.handle.net/1866/4105.
Full textThe clustering of neurons of similar properties is at the basis of the brain modular architecture and is considered as a strategy to optimized processing. One consequence of this clustering is the presence of functional maps in the primary visual cortex of several mammals based on features such as orientation, direction of motion and stimulus position (retinotopy). The first section of this thesis was aimed at characterizing the modular organization of functions in primary and higher-order areas. First, we investigated the possibility that a fundamental cell property, the receptive field center / surround suppression, could be orderly represented in the primary visual cortex. Second, we determined the level of modular organization in area 21a for two key properties, orientation and direction of motion. All studies were based on the optical imaging of intrinsic signals in anesthetized cats. Results indicate the presence of high and low surround suppression modules in the primary visual cortex (areas 17 and 18). To date, such organization has been discovered only in a higher-order area in primate. A modular organization for orientation, similar to the one observed in areas 17 and 18 was observed in area 21a. On the other hand, in contrast to area 18, no direction modules were discovered in area 21a. Overall, the first part of this thesis increased our knowledge about the anatomo-fonctional organization of cat visual cortex. They will also be instrumental to better understand the factors leading to the presence of a modular organization in the cortex. The second section of this thesis was directed to the development of a novel quantitative tool for the temporal analysis of optical imaging intrinsic signals. This new approach, based on Fourier decomposition, allowed to greatly increase the signal to noise ratio of the recordings. Until now, this analysis was only been based on single harmonic quantification, limiting its application for orientation and rétinotopy mapping only. A model exploiting higher harmonics was then developed to estimate additional parameters such as the receptive field size and direction selectivity. Thereafter, this model was validated with success by conventional approaches on the primary visual cortex.
Brais-Brunet, Simon. "Instrumentation et méthodes d’analyse appliquées à l’évaluation du développement rétinien chez le souriceau par tomographie par cohérence optique." Thesis, 2019. http://hdl.handle.net/1866/24516.
Full textThis master thesis is including a manuscript submitted for publication and is divided into two sections. In particular, the document describes the development of optical instrumentation and methodological tools to study the retinal development in an animal model through optical coherence tomography (OCT). The first section is divided into two chapters. Chapter 1 describes the theoretical basis and the problem to solve. Chapter 2 describes the tools developed or adapted to enable the performance of the experiments. In particular, this chapter details the optical system designed to allow the optimal focalization of the light beam onto the retina, which maximizes the signal and minimizes the impact of spherical aberrations and light dispersion on image quality. Also, the processing algorithm used to segment retinal tissues from OCT tomography is discussed. The second section is divided into two chapters. Chapter 3 is a manuscript that was submitted for publication to Investigative Ophthalmology & Visual Science. This work describes the growth and maturation of specific retinal layers in the wild type mouse (129S1/SvImJ) between 7 and 21 days of life. The manuscript also describes the image processing and segmentation algorithm that allows the quantification of the thickness of the layers over time. Then, Chapter 4 describes specific research projects where these OCT imaging tools can be applied. Specifically, this chapter shows the potential to study retinal developmental diseases as well as perfusion methods.