Relevant bibliographies by topics / Traceable delivery

Academic literature on the topic 'Traceable delivery'

Author: Grafiati
Published: 10 December 2022
Last updated: 28 January 2023

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Journal articles on the topic "Traceable delivery"

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Zhang, Huijie, Airan Ding, Baoting Ye, Zhiqing Wang, Jiawen Zhang, Lipeng Qiu, and Jinghua Chen. "Carbon Nitride Nanosheets for Imaging Traceable CpG Oligodeoxynucleotide Delivery." ACS Applied Nano Materials 4, no. 8 (August 10, 2021): 8546–55. http://dx.doi.org/10.1021/acsanm.1c01658.

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Liu, Lei, Yonghong Tang, Sheng Dai, Freddy Kleitz, and Shi Zhang Qiao. "Smart surface-enhanced Raman scattering traceable drug delivery systems." Nanoscale 8, no. 25 (2016): 12803–11. http://dx.doi.org/10.1039/c6nr03869g.

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Gao, X. "Luminescent Qdots for Molecular Imaging and Traceable Drug Delivery." Microscopy and Microanalysis 15, S2 (July 2009): 390–91. http://dx.doi.org/10.1017/s1431927609099528.

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D'souza, Stephanie L., Balaji Deshmukh, Jigna R. Bhamore, Karuna A. Rawat, Nibedita Lenka, and Suresh Kumar Kailasa. "Synthesis of fluorescent nitrogen-doped carbon dots from dried shrimps for cell imaging and boldine drug delivery system." RSC Advances 6, no. 15 (2016): 12169–79. http://dx.doi.org/10.1039/c5ra24621k.

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Fluorescent N-doped carbon dots were synthesized using dried shrimps as precursors and rationally fabricated as a traceable drug delivery system for the targeted delivery of boldine to human breast cancer cells (MCF-7 cells).
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Dong, Jian, Yanli Zhao, Hongyu Chen, Li Liu, Wenxian Zhang, Baoliang Sun, Mingfeng Yang, Yi Wang, and Lifeng Dong. "Fabrication of PEGylated graphitic carbon nitride quantum dots as traceable, pH-sensitive drug delivery systems." New Journal of Chemistry 42, no. 17 (2018): 14263–70. http://dx.doi.org/10.1039/c8nj02542h.

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Ren, Huihui, Shizhu Chen, Yanan Jin, Cuimiao Zhang, Xinjian Yang, Kun Ge, Xing-Jie Liang, Zhenhua Li, and Jinchao Zhang. "A traceable and bone-targeted nanoassembly based on defect-related luminescent mesoporous silica for enhanced osteogenic differentiation." Journal of Materials Chemistry B 5, no. 8 (2017): 1585–93. http://dx.doi.org/10.1039/c6tb02552h.

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Liu, Lei, and Xin Du. "Polyethylenimine-modified graphitic carbon nitride nanosheets: a label-free Raman traceable siRNA delivery system." Journal of Materials Chemistry B 9, no. 34 (2021): 6895–901. http://dx.doi.org/10.1039/d1tb00984b.

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Zeng, Qinghui, Dan Shao, Xu He, Zhongyuan Ren, Wenyu Ji, Chongxin Shan, Songnan Qu, Jing Li, Li Chen, and Qin Li. "Carbon dots as a trackable drug delivery carrier for localized cancer therapy in vivo." Journal of Materials Chemistry B 4, no. 30 (2016): 5119–26. http://dx.doi.org/10.1039/c6tb01259k.

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Song, Chunyuan, Yanxia Dou, Lihui Yuwen, Youzhi Sun, Chen Dong, Fang Li, Yanjun Yang, and Lianhui Wang. "A gold nanoflower-based traceable drug delivery system for intracellular SERS imaging-guided targeted chemo-phototherapy." Journal of Materials Chemistry B 6, no. 19 (2018): 3030–39. http://dx.doi.org/10.1039/c8tb00587g.

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A novel traceable and targeted drug delivery nanosystem with high drug encapsulation and pH-controlled release was prepared based on gold nanoflowers for efficient intracellular SERS imaging-guided chemo-phototherapy.
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Liu, Yang, Haoying Yang, Qian Liu, Mingming Pan, Danli Wang, Shiyuan Pan, Weiran Zhang, Jinfeng Wei, Xiaowei Zhao, and Junfeng Ji. "Selenocystine-Derived Label-Free Fluorescent Schiff Base Nanocomplex for siRNA Delivery Synergistically Kills Cancer Cells." Molecules 27, no. 4 (February 15, 2022): 1302. http://dx.doi.org/10.3390/molecules27041302.

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Chemo and siRNA synergic treatments for tumors is a promising new therapeutic trend. Selenocystine, a selenium analog of cysteine, has been considered a potential antitumor agent due to its redox perturbing role. In this study, we developed a nanocarrier for siRNA based on a selenocystine analog engineered polyetherimide and achieved traceable siRNA delivery and the synergic killing of tumor cells. Notably, we applied the label-free Schiff base fluorescence mechanism, which enabled us to trace the siRNA delivery and to monitor the selenocystine analogs’ local performance. A novel selenocystine-derived fluorescent Schiff base linker was used to crosslink the polyetherimide, thereby generating a traceable siRNA delivery vehicle with green fluorescence. Moreover, we found that this compound induced tumor cells to undergo senescence. Together with the delivery of a siRNA targeting the anti-apoptotic BCL-xl/w genes in senescent cells, it achieved a synergistic inhibition function by inducing both senescence and apoptosis of tumor cells. Therefore, this study provides insights into the development of label-free probes, prodrugs, and materials towards the synergic strategies for cancer therapy.
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Dissertations / Theses on the topic "Traceable delivery"

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Liu, Lei. "Functional composite nanocarriers for traceable drug delivery." Thesis, 2018. http://hdl.handle.net/2440/115216.

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Nowadays, nanoscale drug/gene delivery systems have formed great platforms for modern cancer therapy. Since many nanocarriers were employed for intracellular delivery applications, the potential cytotoxicity of these very small inorganic nanocarriers has raise worldwide considerations. In that case, the intracellular imaging and trace of nanocarriers' delivery performance became of utmost importance. Different analytical techniques have been developed for bio-imaging and tracing applications. Among them, fluorescence imaging is the widely applied one. Although the detecting and analyzing technologies of fluorescence imaging are almost mature, there still existing certain inevitable issues. The fluorescent agents have rapid photo-bleaching properties, so that the fluorescence trace is far away from nondestructive method. Moreover, the auto­ fluorescence of cells can get rise to background interruptions during detecting procedure. On the contrary, the intensities of Raman spectrum are more photo-stable and the Raman signals are easier to separate. The only disadvantage of Raman is that the low Inherent intensity. In that case, surface enhanced Raman scattering (SERS) technology is employed as a solution to that problem. That is why certain part of our research focus on SERS traceable delivery. The aim of this research project is to design and discover a serial of novel functional composite nanocarrier s based on conventional silica and emerging graphitic carbon nitride materials with favourable size, morphology, structure and surface modifications, which can be applied for Raman or Surface-enhanced Raman scattering (SERS) traceable drug/gene delivery. The works included in this thesis are listed as the following. 1) A new smart DDS with 5-10 nm gold nanoparticles aggregated on the surface of silica nanoparticles with an average patticle diameter of ca. 80-100 nm was designed through SERS-traceable nanocarriers baring carboxylic hydrazone-conjugated. This design displays a sesame-bread structure to stimulate SERS effects by the aggregation of small exposed gold seeds. It is evident that the nanocarriers have adequate biocompatibilities, while the smart DDS exhibits selective cytotoxicities between cancer and healthy cells. In here, we confirm the feasibility of SERS traceable drug delivery nanocarriers. 2) A novel stellate porous silica based delivery system was designed for SERS trace purpose. This stellate porous silica pa1ticles with an average particle size of 80-120 nm and center-radial pores of 10-30 nm were coated with in-site reduced gold nanoparticles and could materialise SERS trace after grafted SERS reporters. The trace results show high sensitivity and non-invasive features, which makes the constructed delivery system have considerable potentials to discover the dynamic delivery performances in living cells. In this work, another structured silica-gold composite nanocarrier has been constructed for SERS traceable gene delivery. We prove the SERS traceable nanocarriers could apply for gene delivery. 3) A novel ultrathin graphitic carbon nitride (g-C₃N₄) based system with small sheet size of 100-150 nm and thickness of nearly 0.6 nm was developed for small interfering RNA (siRNA) delivery. The g-C₃N₄ materials were surface modified with low molecular weight branched polyethylenimine (PEI) to obtain the capabilities of siRNA loading. The simple and label-free siRNA delivery system, which avoid possible interactions of artific ial labels, shows cytotoxicity in KHOS cancer cells and good biocompatibility in HEK.293 normal human cells. As g-C₃N₄ is Raman-active, the intracellular uptake performances of the label-free delivery system have been directly traced by Raman spech·oscopies. In th is work, we figured out a new material g-C₃N₄ that can be used for making Raman trace delivery carriers. 4) Advanced label-free g-C₃N₄ composite nanocarriers were designed for surface enhanced Raman scattering (SERS) imaging applications, and smart three-dimensional nanocaniers were constructed for fluorescence imaging applications. By the aggregations of small gold nanoparticles on ultrathin PEI-g-CC₃N₄ nanosheets, the spontaneous Raman intensity of g-C₃N₄ can be enhanced up to 5 orders of magnitude, which makes it possible for high sensitive SERS imaging. On the other hand, by using redox-sensitive non-fluorescent cross-linker to form three-dimensional smart cross-linked-g-C₃N₄ (CL-g-C₃N₄) nanocomposites, the fluorescence imaging of the designed nanocomposites can be specific and show selectivity between healthy and cancer cells. In this work, we find that advanced modified g-C₃N₄ materials have the potentials to be used for the applications of SERS and smait fluorescence traceable delivery. All in all, this project combines the branches of material chemistry, SlU'face chemistry, analytic technology, biology and nano-medicines together. The introduction of emerging SERS imaging and traceable methodology will give certain new knowledge and ideas of nanotechnology and bioengineering. The completion of this project will become the foundation of a series of novel inorganic nanocarriers for drug/gene delivery with outstanding performances like targeting, controllable stimuli-responsive release and higher therapeutic efficiency to against cancers and other human diseases threating on the human health. That is why this project will finally contribute to increase the health and welfare levels of individuals, society and the whole human beings.
Thesis (Ph.D.) (Research by Publication) -- University of Adelaide, School of Chemical Engineering, 2018
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Book chapters on the topic "Traceable delivery"

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Sargent, Mike. "UK delivery of traceable chemical measurements in the 21st century: building on the foundation of the VAM programme." In Traceability in Chemical Measurement, 287–89. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/3-540-27093-0_53.

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Walkey, Carl D., and Warren C. W. Chan. "Quantum Dots for Traceable Therapeutic Delivery." In Cancer Theranostics, 393–417. Elsevier, 2014. http://dx.doi.org/10.1016/b978-0-12-407722-5.00021-9.

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Conference papers on the topic "Traceable delivery"

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Xiaohu Gao. "Traceable siRNA delivery with quantum dots." In 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2009. http://dx.doi.org/10.1109/iembs.2009.5334549.

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Batista, E., A. Furtado, J. Pereira, M. Ferreira, H. Bissig, E. Graham, A. Niemann, A. Timmerman, F. Ogheard, and J. Alves e Sousa. "New EMPIR project – Metrology for Drug Delivery." In 19th International Congress of Metrology (CIM2019), edited by Sandrine Gazal. Les Ulis, France: EDP Sciences, 2019. http://dx.doi.org/10.1051/metrology/201915004.

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This document presents the scientific and technical objectives, state of the art and expected progress beyond it, and most importantly the expected impact on metrology, science, standards, and society of the new joint research project MeDD II, Metrology for drug delivery (follow up of project MeDD I). It was selected for funding through the EURAMET EMPIR program of the European Commission and the participating countries. The project starts in June 2019 and will last for three years. It involves 15 partners from National and Designated Metrology Institutes, companies, and academia. The main objective is to enable traceable measurements of volume, flow and pressure of existing drug delivery devices (for example infusion pumps and analysers) and inline sensors that work at flow rates lower than 100 nL/min, in order to prevent inaccurate measurement results. This project will also investigate fast changing flow rates, liquid mixing behaviour and occlusion phenomena in multi-infusion systems with the purpose of improving dosing accuracy in each infusion line.
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Soluk, Patricia, James Greenwood-Lee, Julie Peschke, Angela Beltaos, Vive Kumar, Ken Munyikwa, Shauna Babiuk, and Shauna Rechseidler-Zenteno. "Building Educational Resilience in Mathematics Delivery and Assessment." In Tenth Pan-Commonwealth Forum on Open Learning. Commonwealth of Learning, 2022. http://dx.doi.org/10.56059/pcf10.616.

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Mathematics is a foundational subject in education. Learning outcomes in mathematics build on previous competencies and students are well-served by real-time intervention and feedback. However, contemporary math education is limited by technology, scalable learning, shareable experiences (both teaching and learning), and accessible modes of practice. Most assessment platforms do not have the functionality to support symbols and equations. During the pandemic we have diverted assessments in high enrolment mathematics courses from paper to electronic delivery. We developed randomized examinations for Introductory Statistics and Introduction to Calculus I and we developed an entire course with assessment using OERs (open educational resources) for Business Mathematics. Our team developed highly interactive, traceable, and intervenable content in math problem solving using the Möbius (https://digitaled.com/mobius) platform. We enabled an LTI integration of the platform into our LMS (learning management system) to provide seamless access for students. Möbius promotes cognitive learning through a powerful math engine, student feedback, analytics, and interactive STEM (science, technology, engineering, math) curriculum content. We are serving 3,000 learners with effective assessment and have relieved faculty and staff of administering and marking alternative examinations through a long pandemic. We have seen improvements in student feedback, increased accessibility, reduced administrative burden, and enhanced exam security. Möbius is a truly scalable and cost-effective platform for math educators and students that provides more efficient and effective management of educational delivery.
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Kurucz, Attila, Fachri Rizky Sitompul, and Edit Süle. "Digitalization of Agri-food Supply Chains: Facts and Promises of Blockchain Technology." In XV. International Conference on Logistics in Agriculture 2021. University of Maribor Press, 2021. http://dx.doi.org/10.18690/978-961-286-538-2.3.

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With the globalization agri-food supply chains become longer and more complex, what makes it difficult to manage. parallel with this there is increasing customer demand for knowing the origin, ingredients and delivery chain of agricultural products. the need for more efficient, traceable and visible supply chain for agri-food products appears from supply side. The digital methods of industry 4.0 are able to provide solutions for these demands particularly those which are able to trace product reliable way from its origin to consumption. blockchain is a disruptive technology by which every important product information can be collected, stored and shared with the actors involved in the product process chain from the first phase to the final customer. The paper provides an overview about blockchain technology and its operation in agri-food supply chains environment, then presents some examples from the practice of different countries where blockchain was applied in the agricultural sector in order to introduce experiences as facts, and further possibilities as promises by blockchain.
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Sahoo, Subrat. "RFID-GPS Enabled Project Material Control." In ADIPEC. SPE, 2022. http://dx.doi.org/10.2118/210814-ms.

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Abstract Material control plays a vital role in the success of any construction linked Project. Any deviation in material identification and traceability due to human error, leads to cost and time impact due to shortages, delays due to re-ordering and price escalation. Radio Frequency Identification (RFID) device coupled with Global Positioning System (GPS) technology helps in maintaining real-time material database, with real-time location of materials at all stages of the project. RFID technology helps in the material identification and RFID tags are used for locating the materials utilizing the contact-less RFID reader. GPS technology helps in material positioning segment indicating the material location in the designated grid. RFID and GPS together establish their coordinates which instantly detects the material position and indicates an image of the storage yard digitally on the screen that eases material traceability in the designated space. Implementation of an RFID-GPS enabled material control system creates a dynamic material database that brings in transparency and real-time information on material status. RFID-GPS system enables ‘End to End’ Material Tracking with updated real-time data and physical availability status throughout project duration starting from the receipt, storage, issuance and further installation at site till start-up. RFID-GPS enabled system ensures faster delivery of material information as compared to the manual processes and aids material coordinator with reliable information that can help to take decisions for optimization of the project vitals. Real-time information about material receipt upon entry into project premises without time lag helps to acknowledge missing items and generate short supply materials instantly, thereby averting schedule disruption. Any missing or un-traceable material is notified well in advance for timely action. Dynamic material database keeps all stakeholders in unison on the inventory status and can reduce incidents or loss of material from site. The system has definite advantage of reducing the Construction man-days lost due to re-works arising out of material identification, searching, segregation based on material composition. RFID systems have the potential to improve work productivity and enhancing better project schedule adherence, overcoming human error in manual material control at project sites.
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Stokes, Timothy, and Sue Cox. "Improving Safety and Security Management Programs to Realize Successful Outcomes by Focusing on Requirements Management." In 2012 Joint Rail Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/jrc2012-74082.

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A vital aspect of safety and security management during the development of new rail and transit projects is ensuring that safety and security requirements are properly developed and incorporated into the work products in a planned, systematic and traceable manner. The completed rail or transit project will need to operate as a fully integrated system, but it will likely be designed, supplied, constructed and tested by many parties organized through multiple contracts. Each contracted entity has a responsibility to do some aspect of the work, and can have an impact on the safety and security of the completed rail or transit project. In addition, other impacts to safety and security can arise from system interfaces and inter-modal systems, from other rail and bus systems servicing the corridor/region to highways, bike, pedestrian walkways and para-transit. This paper discusses the critical role of safety and security requirements management during the development and delivery of rail or transit projects to ensure that safety and security is inherent in the project, consistent with US DOT regulations. Safety and security requirements management should be an integrated part of project management, rather than an after-thought at the end of the project. Requirements are not prescribed solutions; rather they are explicit statements, categorized into a logical framework, describing the functions, behaviors and qualities to be achieved. Requirements are typically specified by the owner to express what a new rail or transit project needs to accomplish from an operations perspective. Amongst the project requirements are the safety and security requirements that must be satisfied. The designer proposes a solution to satisfy the requirements, taking into account risk, cost, schedule, and other constraints such as technical issues and human factors. By using the techniques of requirements management, owners of rail and transit properties will have visibility into the status of safety and security throughout project implementation to facilitate control over the project to realize successful outcomes. It should be noted that requirements management techniques are also applicable during the operations and maintenance, retrofit and disposal phases of a rail or transit project. Managing safety and security requirements including the verification process in a planned, systematic and documented manner confirms to the owner, operators, oversight agencies and the general public that safety and security risks have been appropriately taken into account. Thus the owner can ultimately state with confidence that the completed system is safe for operations and public use.
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McQuillan, Kevin W., Gary L. Milne, and Gavin Smith. "Achieving a Leak Free Start Up: Impossible Dream or Achievable Project?" In ASME 2003 Pressure Vessels and Piping Conference. ASMEDC, 2003. http://dx.doi.org/10.1115/pvp2003-1871.

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Large petrochemical plants are shutdown periodically for maintenance and inspection. During the shutdowns a large number of gasketted joints are dismantled in order to gain access to the equipment, and subsequently remade at the end of the shutdown. In order to ensure the integrity of the pressure envelope, the plant systems are leak tested with high-pressure nitrogen prior to the introduction of hydrocarbons. If leaks from gasketted joints are discovered during this process, it becomes necessary to de-pressure the systems in order that the joints can be remade. During the 1990 Shutdown of the Huntsman Olefins6 plant at Wilton, approximately 200 gasketted joints were required to be remade during leak testing. This caused significant and costly delays to the start up of the plant. Later analysis showed that the leaks were the result of poor standards in the making and checking of the gasketted joints. A new joint making procedure was written for the 1993 and 1997 shutdowns, and this included a requirement for joints to be traceable by a tagging system to the technician who made the joint. The number of remakes reduced dramatically, to approximately 10 in each of the two shutdowns. In preparation for the 2002 shutdown engineers at Wilton set a target of achieving ZERO remakes during leak testing after the shutdown. This was a great challenge, especially given that approximately 7000 joints were to be remade by 400 technicians. The project was developed in partnership with Hedley Purvis Limited, who supplied design services for calculating residual bolt loads, and Klinger UK Limited, who supplied gaskets for use during the shutdown. The Olefins Joint Making procedure was further developed, requiring full traceability and the use of controlled tightening of joints to a pre-defined load. Great emphasis was placed on the role of people in effective joint making, and in ensuring that each technician was carefully briefed and validated in his understanding of the importance to the business of high standards in joint making. A training video was prepared to help in the process of gaining the understanding and involvement of the technicians and their supervisors. Hedley Purvis and Klinger supported Huntsman in the development of the video, and in the delivery of the training and validation exercise. The project was a great success, and resulted in the first “leak free” start up of the Olefins6 plant. The paper will described the project in detail, and will include a showing of the training video.
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Town, Nigel, Aidan Goldsworth, and Steven Lawler. "Meeting the Challenge." In ASME 2011 Small Modular Reactors Symposium. ASMEDC, 2011. http://dx.doi.org/10.1115/smr2011-6646.

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The market forecast for Small Reactor applications varies dependent upon the intelligence source used. It is nevertheless clear that the forecasted market volume presents a significantly different challenge to anything the nuclear industry has previously encountered. The industry response to this challenge could be evolutionary or revolutionary. Evolution could be considered the traditional, more relaxed approach as manufacturing capacity and validation techniques develop in-line with market growth & demand. However this approach would not deliver the level of manufacturing efficiencies required to support the Small Reactor programs. Industry must therefore take a revolutionary approach and look towards process optimization, with a focus on design for manufacture (DFM) and design for assembly (DFA). With manufacturing & assembly facilities tailored to meet this challenge, there is an opportunity to introduce new manufacturing philosophies such as ‘flowline’ manufacture — a hybrid between production line and batch processing techniques. Flowline manufacture is a product-oriented manufacturing technique which benefits from aspects of production line approach, e.g. standardized tasks, standardized tooling, and standardized processes. This approach offers an opportunity to validate & verify product parameters during the assembly stage, eliminate non-value added activities, and deliver a Small Reactor product to the required volume demand in a controlled, traceable, safe and reliable manner.
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Matharu, Ranveer S., Wayne Sadler, Bekim V. Gashi, and Trevor Toman. "Investigation in optimisation of accuracy with non-contact systems by influencing variable processes." In 19th International Congress of Metrology (CIM2019), edited by Sandrine Gazal. Les Ulis, France: EDP Sciences, 2019. http://dx.doi.org/10.1051/metrology/201909004.

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The use of 3D scanning systems is becoming increasingly popular and an essential tool for manufacturers for inspection and measurement. With such systems being utilised on the manufacturing shop floor due to their portability and ease of use, it is no doubt that such systems are designed to address a variety of users whom, with minimal training can operate the equipment. Due to continuing demands of high-quality products there is the need for manufacturers of 3D scanning systems to develop technologies that deliver fast and accurate information. However, one of the key challenges lies not in the training of people to use the equipment, but to develop engineers who can produce traceable, accurate and precise results with a declared statement of confidence quantifying the quality of the measurement. This statement of the quality of the output results relies on employing a set of workflow actions that involve planning, capture, processing and analysis, and finally output. This paper sets out to show how the results from a set of workflow actions from different categories of 3D scanning devices affects the quality of output.
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VAT, Kam. "Modeling Human Activity Systems for Collaborative Project Development: An IS Development Perspective." In InSITE 2005: Informing Science + IT Education Conference. Informing Science Institute, 2005. http://dx.doi.org/10.28945/2846.

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This paper investigates the idea of human activity systems (HAS) appropriate to the characterization of the purposeful human activities behind the design of suitable information systems (IS) support, especially in the context of group-based project work. Specifically, we are interested in the knowledge context of a group of people collaborating in the peculiar scenario of project development. Our discussion describes a traceable framework of information systems development (ISD), which should accommodate the application of soft systems methodology (SSM) that acknowledges the importance of people in organization. The paper situates our discussion in the action research experience of the author conducting a junior core course of Software Psychology, delivered through the pedagogy of problem-based learning (PBL), in our four-year undergraduate program of Software Engineering. We intend to clarify the contextualization of designing IS support in relation to teamwork design. This is done by elaborating the IS design issues through the exposition of the human processes in which, in a specific organizational scenario, a particular group of people can conceptualize their world and hence the purposeful action they wish to undertake. That provides the basis for ascertaining what IS support is needed to undertake the necessary action and how modern information technology (IT) can help to provide that support. We conclude by reiterating the challenge of designing truly relevant HAS systems in which people selectively perceive parts of their world, attribute meaning to what they perceive, make judgment about their perceptions, form intentions to take particular actions, and carry out the action themselves. All these activities carry tremendous connotations in the HAS-based process of IS development for group project work, especially in collaborative project participation.
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