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Academic literature on the topic 'Tonsille palatine – Cancer'
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Journal articles on the topic "Tonsille palatine – Cancer"
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Kim, Tae-Yoon, Ji Young Lee, Young-Jun Lee, Dong Woo Park, Kyung Tae, and Yun Young Choi. "CT texture analysis of tonsil cancer: Discrimination from normal palatine tonsils." PLOS ONE 16, no. 8 (August 11, 2021): e0255835. http://dx.doi.org/10.1371/journal.pone.0255835.
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The purposes of the study were to determine whether there are differences in texture analysis parameters between tonsil cancers and normal tonsils, and to correlate texture analysis with 18F-FDG PET/CT to investigate the relationship between texture analysis and metabolic parameters. Sixty-four patients with squamous cell carcinoma of the palatine tonsil were included. A ROI was drawn, including all slices, to involve the entire tumor. The contralateral normal tonsil was used for comparison with the tumors. Texture analysis parameters, mean, standard deviation (SD), entropy, mean positive pixels, skewness, and kurtosis were obtained using commercially available software. Parameters were compared between the tumor and the normal palatine tonsils. Comparisons were also performed among early tonsil cancer, advanced tonsil cancer, and normal tonsils. An ROC curve analysis was performed to assess discrimination of tumor from normal tonsils. Correlation between texture analysis and 18F-FDG PET/CT was performed. Compared to normal tonsils, the tumors showed a significantly lower mean, higher SD, higher entropy, lower skewness, and higher kurtosis on most filters (p<0.001). On comparisons among normal tonsils, early cancers, and advanced tonsil cancers, SD and entropy showed significantly higher values on all filters (p<0.001) between early cancers and normal tonsils. The AUC from the ROC analysis was 0.91, obtained from the entropy. A mild correlation was shown between texture parameters and metabolic parameters. The texture analysis parameters, especially entropy, showed significant differences in contrast-enhanced CT results between tumor and normal tonsils, and between early tonsil cancers and normal tonsils. Texture analysis can be useful as an adjunctive tool for the diagnosis of tonsil cancers.
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Arvisais-Anhalt, Simone, Andrew Quinn, Justin A. Bishop, Cynthia S. Wang, Ron B. Mitchell, Romaine F. Johnson, Barbara Schultz, and Andrew T. Day. "Palatine Tonsilloliths and Actinomyces: A Multi-institutional Study of Adult Patients Undergoing Tonsillectomy." Otolaryngology–Head and Neck Surgery 163, no. 4 (May 5, 2020): 743–49. http://dx.doi.org/10.1177/0194599820921392.
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Objective To better characterize associations between Actinomyces and tonsillolith versus nontonsillolith tonsillectomy specimens. Study Design Bi-institutional retrospective case-case study. Setting University and county hospital. Subjects and Methods Adult patients with a clinical history of tonsilloliths who underwent tonsillectomy from January 2006 to December 2018 were included. Patients undergoing tonsillectomy for tonsillar hypertrophy and chronic tonsillitis were identified as comparative cases. Similarly, patients with ipsilateral oropharyngeal cancer (OPC) who underwent contralateral tonsillectomy of a normal-appearing tonsil for prophylaxis against a second primary cancer were also included as comparative cases. Results The study population comprised 134 patients who underwent tonsillectomy: 62 tonsillolith and 72 nontonsillolith (tonsillar hypertrophy, n = 30; chronic tonsillitis, n = 30; normal-appearing contralateral tonsil in patients with ipsilateral OPC, n = 12). Actinomyces was reported in 11% of the patients with tonsilloliths on initial pathology reports but in 95% after re-evaluation (n = 54 of 57). Actinomyces prevalence was significantly higher in patients with tonsilloliths as compared with patients with recurrent tonsillitis (73%, n = 22 of 30, P < .001) and normal-appearing contralateral tonsils in patients with ipsilateral OPC (58%, n = 7 of 12, P < .001). Actinomyces prevalence was not significantly different between patients with tonsilloliths and tonsillar hypertrophy (83%, n = 25 of 30, P = .11). Conclusion The prevalence of Actinomyces in tonsillolith tonsil specimens is high; however, Actinomyces routinely colonizes nontonsillolith tonsil specimens. Therefore, Actinomyces is unlikely to be the primary driver of tonsillolith pathogenesis, and Actinomyces-targeted treatment of tonsilloliths may not be effective. Treatment strategies addressing tonsilloliths should be further investigated.
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Kaczmarczyk, Dariusz, Dawid Zagacki, Marcin Braun, and Alina Morawiec-Sztandera. "Gastric carcinoma metastasis to the palatine tonsil – case report." Polski Przegląd Otorynolaryngologiczny 9, no. 1 (March 20, 2020): 50–53. http://dx.doi.org/10.5604/01.3001.0014.0309.
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<b>Aim:</b> The aim of the study is to present a rare case of metastatic tumor localized in pharyngeal tonsil being the first symptom of gastric carcinoma. <br><b>Case report:</b> Retrospective analysis of medical documentation was performed. A 44-years-old men was referred to the Department presenting a complaint of enlarged right pharyngeal tonsil. The mass was not painful. Patient reported tobacco smoking (20/day) for many years. In the intraoral examination a 2 cm right palatine tonsil was present. There was a slight asymmetry between tonsils. Local lymph nodes were not enlarged. FNAC was performed stating suspicion of carcinoma. Patient was qualified for the tonsillectomy under general anesthesia. Histopathological finding was adenocarcinoma (G2) infiltration. Due to no correlation of clinical presentation and histopathological finding PET-CT examination was performed revealing massive gastric infiltration, tumor of the left adrenal gland, increased 18-FDG uptake in epigastrial and para-aortic lymph nodes. Gastroscopy and biopsy was performed. Histopathological material confirmed adenocarcinoma presenting the same immunotype as tonsillar. Patient was qualified for paliative treatment. He died 6 weeks after stating the diagnosis. Metastases to the pharyngeal tonsils constitute rare disease entities. Mostly the primary site is localized in the region of head and neck. In our case the metastatic tumor of the right tonsil was the first sign of the gastric cancer.
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Serra, A., R. Caltabiano, G. Scalia, S. Palmucci, P. Di Mauro, and S. Cocuzza. "Papillary squamous cell carcinoma of the palatine tonsil: a rare cancer of the head and neck." Acta Otorhinolaryngologica Italica 37, no. 4 (August 2017): 341–45. http://dx.doi.org/10.14639/0392-100x-1281.
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Le neoplasie squamose papillari delle vie aeree digestive superiori sono una rara variante del carcinoma a cellule squamose. Sono caratterizzate da una crescita esofitica papillare e hanno una prognosi generalmente favorevole. Il tumore è già stato descritto a livello delle vie aeree digestive superiori. In tale contesto, le localizzazioni più frequenti sono la laringe e lipofaringe, mentre raramente sono interessati la cavità orale e lipofaringe. Gli studi limitati unitamente allesiguo numero di casi pubblicati di carcinoma squamoso papillare a localizzazione tonsillare, ci hanno indotto a una completa analisi di questo tumore, analizzando gli aspetti clinici, istopatologici, radiologici, virologici e terapeutici, non sempre presenti in letteratura. Un case report di carcinoma squamoso papillare della tonsilla palatina è pertanto riportato. La lesione (T2N0M0), localizzata a livello della tonsilla palatina sinistra, si aggettava verso la cavità orale. HPV DNA 16 e mRNA E6/E7 erano rilevati nella lesione. Un profilo della neoplasia è pertanto presentato unitamente a una completa revisione della recente letteratura, analizzando tutti gli aspetti di interesse di tale neoplasia.
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Aloyouny, Ashwag Yagoub. "Unusual Site for a White Nodule on the Palatine Tonsil: Presentation, Differential Diagnosis, and Discussion." Case Reports in Dentistry 2021 (July 8, 2021): 1–4. http://dx.doi.org/10.1155/2021/1371329.
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Introduction. Palatine tonsils are part of the mucosa-associated lymphoid tissue, located in the oropharyngeal region. Although these tissues protect the body from foreign intruders, they are more prone to infections due to their anatomical structure and location. For instance, the differential diagnosis of a white lesion on the palatine tonsil can range from benign to malignant lesions. Oral lymphoepithelial cysts commonly arise as painless, yellowish nodules on the floor of the mouth and the ventral or lateral surface of the tongue. Case Presentation. This paper presents a rare case of an unusual site of a lymphoepithelial cyst (LEC) in the oral cavity. The lesion was located in the tonsil of a 20-year-old woman with a chief complaint of a painless, white lump in the back of the mouth for nine months. Discussion. The differential diagnosis of a white lesion on the palatine tonsil is caused by several factors, such as bacterial, viral, and fungal infections; trauma; stones; cysts; abscess; or cancer. In this case, both the clinical presentation and extra- and intraoral examinations were highly associated with LEC. Oral LEC etiopathogenesis is uncertain, and several theories have been proposed to discuss the causes of LEC. In addition, oral LEC could be monitored without surgical intervention if the nodule is asymptomatic. Conclusion. We emphasize the importance of a thorough clinical examination of oral and oropharyngeal lesions, which are usually neglected.
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Astl, Jaromír, Richard Holy, Eva Maute, Jan Rotnágl, David Kalfeřt, Barbora Drnková, Temoore Younus, and Emil Pavlík. "Genome of Helicobacter pylori and Serotype of HPV Detected in Oropharyngeal and Laryngeal Cancer and Chronic Inflammation Patients." International Journal of Environmental Research and Public Health 18, no. 18 (September 10, 2021): 9545. http://dx.doi.org/10.3390/ijerph18189545.
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Objective: Oropharyngeal/laryngeal carcinoma are common cancers of the upper aerodigestive system. Human papillomavirus (HPV) is described as the most frequent in the cancer of unknown primary. The presence of Helicobacter pylori (HP) in the oral cavity is discussed in some papers. The aim of study: To analyze the incidence of HPV and HP in oropharyngeal/laryngeal cancer persons versus persons with chronic tonsillar inflammation and healthy persons. Methods: The samples were taken in three groups: (1) tissue of oropharynx/larynx cancer (103 specimens); (2) tissue of palatine tonsils (85 specimens); and (3) healthy control group (50 specimens). We analyzed the presence of HP (PCR) and HPV genomic DNA (Sacace HPV High-Risk Screen Real-TM Quant) in the samples. Results: HP was detected in 86 samples (83.5%) and high-risk HPV in 62 samples (60.2%). We found a very high incidence of HP. In the cancer group, HP was detected in 82.5% cases and HPV positivity in 57.8%. In total, 7.2% of the cancer patients were negative for HP and HPV together. In turn, 53.6% of the cancer patients were positive for HP and HPV together. Four cases (4.2%) were positive for HPV only. VacA positivity was detected in 82 (79.6%) of the cancer cases and VacA negativity in 21 (20.4%) if the cancer cases. The incidence of HP in chronic inflammation (n = 85) was 65 cases (76.5%) and the incidence of HPV was 38 cases (44.7%). VacA positivity was detected in 59 (69.4%) of the chronic inflammation cases and VacA negativity was found in 26 (30.6%) of the chronic inflammation cases. Regarding the control group, we found HP positivity in 5 cases (11.1%) and HPV positivity in 19 cases (42.2%). There was VacA positivity in 6 cases (50.0%) of the control group. Statistically significantly lower prevalence of HP (p < 0.001) and HPV (p = 0.006) was found in the control group. Conclusions: We suggest that the palatine tonsils are colonized by HP. In our study, HP was present in oropharyngeal cancer in more cases in comparison with HPV infection. The presence of VacA from HP can have an influence on the human epithelial and immune cells’ regulation ways. Our results do not support idea that the CagA-positive HP is a primary carcinogen in oropharyngeal area.
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Ishikawa, Yasuyuki, and Masanao Okawa. "Primary multiple cancers of the palatine tonsil and parotid gland." Practica Oto-Rhino-Laryngologica 78, no. 11 (1985): 2359–65. http://dx.doi.org/10.5631/jibirin.78.2359.
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Spellman, Joseph, Ryan Sload, Paul Kim, Peter Martin, and Gabriel Calzada. "Staging Neck Dissection and Transoral Robotic Surgery Treatment Algorithm in Palatine Tonsil Cancer." Otolaryngology–Head and Neck Surgery 158, no. 3 (November 21, 2017): 479–83. http://dx.doi.org/10.1177/0194599817742615.
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Objective This study introduces a treatment algorithm based on staging neck dissection to identify patients with palatine tonsil squamous cell carcinoma who can be effectively treated with single-modality transoral robotic surgery while maintaining quality of life. Study Design Retrospective case series. Setting Kaiser Permanente Southern California Medical Group from 2012 to 2017. Subjects and Methods Patients with early-stage (T1/2) palatine tonsil squamous cell carcinoma with clinically and radiographically N0 necks underwent staging neck dissection. Those with pN2/3 disease or extracapsular extension on final pathology were triaged to definitive chemoradiation treatment. Patients with confirmed pN0/1 necks without extracapsular extension were treated definitively with transoral robotic surgery. Results Nineteen patients with cN0 disease underwent selective neck dissection. All were p16 positive. Of these, 14 had pathologically confirmed N0/1 necks without extracapsular extension and were treated with primary surgical resection via transoral robotic surgery. Clear margins were obtained on all patients. There were no significant intra- or postoperative complications. No patients required gastrostomy tube or tracheostomy placement. Mean and median follow-up was 28 months with no recurrences to date. Conclusion Up-front staging neck dissection accurately triages low-risk patients, determining candidates for single-modality definitive treatment with transoral robotic surgery. This approach provides excellent survival outcomes and minimal morbidity and maintains quality of life among appropriately selected patients with palatine tonsil cancer.
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Vrînceanu, Daniela, M. Dumitru, and Carmen Maria Ardeleanu. "MALIGNIZED BRANCHIAL CYST OR CERVICAL METASTATIC ADENOPATHY WITH PRIMARY TUMOR IN A TONSILLAR HIDDEN CARCINOMA?" Journal of Surgical Sciences 7, no. 1 (January 24, 2020): 169–74. http://dx.doi.org/10.33695/jss.v7i1.306.
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Cancer of occult origin is defined as a group of primary tumors with metastatic determinations, most commonly lymph nodes for which diagnostic algorithms fail to identify the place of origin of the primary tumor at the time of positive metastasis diagnosis. Squamous cell carcinoma with a truly unknown primary office is a relatively rare entity in the region of the head and neck. Retrospective studies suggest that it accounts for 1-3% of new cases of squamous cell carcinoma of the head and neck. We will present the clinical case of a 76-year-old patient with metastatic left-cervical cystic metastatic adenopathy, initially interpreted as a malignant branchial cyst. Discrepancies in histopathological examination, imaging and clinical examination delayed the performance of adjuvant radiotherapy. We will present details of diagnosis and evolution of the case. The results of the systematic literature review suggest that palatal tonsillectomy has a high overall rate of detection of subclinical primary tumors. Given the significant number of bilateral / contralateral occult tonsil tumors reported in the specialty literature, bilateral tonsillectomy should be considered in determining the diagnosis of squamous cell carcinoma patients of unknown primary origin in the head and neck. Cervical lymph node metastasis with unknown primary tumor remains a difficult topic for head and neck oncology. Most diagnostic and treatment protocols recommend unilateral or bilateral tonsillectomy, with an increased chance of finding an occult tumor in the palatine, unilateral or bilateral tonsils. In the presence of a cystic cervical lymph node metastasis, the first location should be considered as the primary tumor site must be the palatine tonsil.
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Golas, Sylvia M. "Trends in palatine tonsillar cancer incidence and mortality rates in the United States." Community Dentistry and Oral Epidemiology 35, no. 2 (April 2007): 98–108. http://dx.doi.org/10.1111/j.1600-0528.2007.00299.x.
Full textDissertations / Theses on the topic "Tonsille palatine – Cancer"
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Marmouset, Franck. "Epithéliomas de la région amygdalienne : à propos de186 cas." Montpellier 1, 1991. http://www.theses.fr/1991MON11056.
Full textBooks on the topic "Tonsille palatine – Cancer"
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Hashibe, Mia, Erich M. Sturgis, Jacques Ferlay, and Deborah M. Winn. Oral Cavity, Oropharynx, Lip, and Salivary Glands. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190238667.003.0029.
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Cancers of the oral cavity, oropharynx, lip, and salivary glands are malignancies of the head and neck. Some of these cancer sites share risk factors, although each has distinctive anatomic, epidemiologic, and clinical features. Oral cavity cancers arise on the inner lip and buccal mucosa, anterior two-thirds of the tongue, gum, hard palate, and floor of mouth. These cancers are strongly associated with the use of smoked and smokeless tobacco products, heavy alcohol consumption, and chewing of betel quid or pan, but only minimally associated with prior infection with human papillomavirus (HPV). In contrast, oropharyngeal cancers affect the posterior one-third (base) of the tongue, tonsils, soft palate, and other oropharyngeal tissues and are strongly associated with HPV-16 infection as well as with the use of tobacco, alcohol, and betel quid. In principle, tumors of the oral cavity, oropharynx, and lip are among the most preventable forms of cancer.
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Rider, Jennifer R., Paul Brennan, and Pagona Lagiou. Oral and Pharyngeal Cancer. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190676827.003.0007.
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This chapter covers cancer of the oral cavity and the oropharynx, which includes the base of the tongue, soft palate, tonsils, and back and side walls of the throat. Many important risk factors for oral and oropharyngeal cancer have been identified, and in 2007 the World Health Organization determined there was sufficient evidence to include human papilloma virus (HPV) type 16 as a cause of these cancers. Tobacco and alcohol remain important modifiable risk factors, but the increasing incidence of HPV-associated tumors is now evident. While these tumors are more amenable to treatment than HPV-negative tumors, they are still a source of considerable morbidity and mortality. Moreover, the lack of a precursor lesion and limited data on efficacy of the HPV vaccine in preventing oral HPV infection are barriers to primary and secondary prevention efforts. Dietary patterns high in fruits and vegetables and low in meats may confer some protection.