Academic literature on the topic 'Tocotrienol'
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Journal articles on the topic "Tocotrienol"
Che, Hui-Ling, Doryn Meam-Yee Tan, Puvaneswari Meganathan, Yee-Lin Gan, Ghazali Abdul Razak, and Ju-Yen Fu. "Validation of a HPLC/FLD Method for Quantification of Tocotrienols in Human Plasma." International Journal of Analytical Chemistry 2015 (2015): 1–7. http://dx.doi.org/10.1155/2015/357609.
Full textShah, Sumit J., and Paul W. Sylvester. "Tocotrienol-induced cytotoxicity is unrelated to mitochondrial stress apoptotic signaling in neoplastic mammary epithelial cells." Biochemistry and Cell Biology 83, no. 1 (February 1, 2005): 86–95. http://dx.doi.org/10.1139/o04-127.
Full textLachman, Jaromír, Alena Hejtmánková, Zora Kotíková, Martin Dědina, Radomíra Střalková, and Vladimír Hönig. "Stability of Grape Seed Oil and its Antioxidant Tocotrienols." Advanced Materials Research 1030-1032 (September 2014): 370–73. http://dx.doi.org/10.4028/www.scientific.net/amr.1030-1032.370.
Full textMo, Huanbiao, Wei Wei, Sophie Yount, Zachary Allen, Katherine Bechdol, Weiming Xia, and Angela Mabb. "δ-Tocotrienol Increases Hippocampal Network Excitability Through Upregulation of GluA1-Containing AMPA Receptors." Current Developments in Nutrition 4, Supplement_2 (May 29, 2020): 1225. http://dx.doi.org/10.1093/cdn/nzaa057_041.
Full textYuen, Kah Hay, Jia Woei Wong, Ai Beoy Lim, Bee Hong Ng, and Wai Peng Choy. "Effect of Mixed-Tocotrienols in Hypercholesterolemic Subjects." Functional Foods in Health and Disease 1, no. 3 (March 31, 2011): 106. http://dx.doi.org/10.31989/ffhd.v1i3.136.
Full textSerbinova, Elena A., and Lester Packer. "Antioxidant and Biological Activities of Palm Oil Vitamin E." Food and Nutrition Bulletin 15, no. 2 (June 1994): 1–6. http://dx.doi.org/10.1177/156482659401500213.
Full textSuminar, Mentari Mayang, and Mahdi Jufri. "PHYSICAL STABILITY AND ANTIOXIDANT ACTIVITY ASSAY OF A NANOEMULSION GEL FORMULATION CONTAINING TOCOTRIENOL." International Journal of Applied Pharmaceutics 9 (October 30, 2017): 140. http://dx.doi.org/10.22159/ijap.2017.v9s1.74_81.
Full textNair, Anroop B., Bapi Gorain, Manisha Pandey, Shery Jacob, Pottathil Shinu, Bandar Aldhubiab, Rashed M. Almuqbil, Heba S. Elsewedy, and Mohamed A. Morsy. "Tocotrienol in the Treatment of Topical Wounds: Recent Updates." Pharmaceutics 14, no. 11 (November 16, 2022): 2479. http://dx.doi.org/10.3390/pharmaceutics14112479.
Full textMohd Fozi, Nur Farhana, James Jam Jolly, Kien Hui Chua, Ekram Alias, Kok Yong Chin, and Ima Nirwana Soelaiman. "Comparing the Effects of Alpha-Tocopherol and Tocotrienol Isomers on Osteoblasts hFOB 1.19 Cultured on Bovine Bone Scaffold." Sains Malaysiana 50, no. 8 (August 31, 2021): 2319–28. http://dx.doi.org/10.17576/jsm-2021-5008-15.
Full textNuman, Abdul Hadi, and Mei Han Ng. "Selective Separation of Tocol Homologues by Liquid-Liquid Extraction Using Choline-Based Deep Eutectic Solvents." Trends in Sciences 20, no. 2 (November 30, 2022): 6432. http://dx.doi.org/10.48048/tis.2023.6432.
Full textDissertations / Theses on the topic "Tocotrienol"
Tan, Sue See. "Antioxidant properties of tocopherol and tocotrienol." Thesis, University of Reading, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.494987.
Full textPark, Han-A. "Natural Vitamin E, α-Tocotrienol, as a Neuroprotectant." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1291061955.
Full textFu, Ju Yen. "Preparation and evaluation of tumour-targeted delivery systems for tocotrienol." Thesis, University of Strathclyde, 2010. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=22629.
Full textGerling, Eva-Maria [Verfasser]. "Stabilität von Vitamin E (α-Tocotrienol, α- Tocopherol, γ-Tocotrienol und γ-Tocopherol) in Rohwürsten und Pökellake: Einfluss von Zusatzstoffen und Lagerung / Eva-Maria Gerling." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2015. http://d-nb.info/1073848388/34.
Full textRosa, Maria Thereza de Moraes Gomes 1986. "Aplicação e potencial das tecnologias de micronização e emulsificação para o processamento de produtos alimentícios e farmacêuticos = Applications and potential of micronization and emulsification technologies in food and pharmaceutical processing." [s.n.], 2015. http://repositorio.unicamp.br/jspui/handle/REPOSIP/254914.
Full textTese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia de Alimentos
Made available in DSpace on 2018-08-27T12:15:27Z (GMT). No. of bitstreams: 1 Rosa_MariaTherezadeMoraesGomes_D.pdf: 4902896 bytes, checksum: aef7e5c464da3869257ebd47ad538611 (MD5) Previous issue date: 2015
Resumo: O presente trabalho de doutorado está dividido em dois temas principais, um sobre o uso da tecnologia supercrítica para a formação de partículas e outro sobre o uso do ultrassom para a formulação de emulsões. A revisão da literatura sobre o estado da arte do emprego do CO2 supercrítico para formação de micro e nanopartículas e encapsulação mostrou as potencialidades do uso desta tecnologia. A unidade usada para os experimentos de micronização via tecnologia supercrítica foi desenvolvida pelo grupo de pesquisa e validada utilizando uma substância modelo, o sal de ibuprofeno sódico. Esse fármaco foi selecionado devido às informações sobre o sistema CO2-Ibuprofeno encontradas na literatura. O efeito das condições operacionais (temperatura, pressão, vazão da solução, vazão do CO2, tipo de injetor e concentração de ibuprofeno sódico na solução etanólica) no rendimento de precipitação, teor de solvente residual, morfologia das partículas e consumo energético por unidade de produto processado foi investigado utilizando o método split-plot. Sal de ibuprofeno sódico foi micronizado com sucesso via Antissolvente Supercrítico (SAS) utilizando a unidade construída. A vazão de CO2 influenciou estatisticamente no rendimento de precipitação, enquanto que, não houve influência das condições operacionais no teor de solvente residual das partículas micronizadas. Com a apropriada seleção das condições operacionais, foi possível a obtenção de partículas de ibuprofeno sódico com morfologia de folha, sendo ideal para os processos de compressão do fármaco, com baixo teor de solvente residual e alto rendimento de precipitação. Neste trabalho também foi explorado o uso do ultrassom para a formulação de emulsões, contendo extrato rico em 'delta'-tocotrienol, com o intuito de aumentar o valor agregado deste extrato obtido das sementes de urucum por extração supercrítica com dióxido de carbono. As sementes de urucum já são valiosas pela característica de produzir pigmentos, a bixina e a norbixina. Contudo, essas sementes também vêm adquirindo notoriedade por conter outras substâncias de importância para a saúde do homem, como tocoferóis, tocotrienóis e geranil geraniol. Devido à importância desses compostos bioativos, que apresentam propriedades antioxidade, hidratante e fotoprotetora, este estudo visou o desenvolvimento de métodos para formação de emulsões permitindo a proteção desses compostos instáveis às condições adversas, aumentando assim o valor agregado dos extratos obtidos das sementes de urucum. Extrato de raiz de ginseng brasileiro, rico em saponinas, foi utilizado como biossurfactante. Adicionalmente, emulsões foram obtidas utilizando um homogeneizador tipo dispersor de fase múltipla na mesma densidade energética que foi aplicada no ultrassom. A influência do processo de emulsificação, densidade energética, concentração do biosurfactante, tipo de óleo e de biosurfactante no tamanho de gota e estabilidade da emulsão foi investigada. Os resultados indicaram que o extrato rico em saponinas pode ser uma boa opção para formulação de emulsões para aplicação em produtos alimentícios. Miniemulsões, com tamanho de gota variando entre 0,35 e 0,83 µm, foram obtidas, sendo que os menores tamanhos de gota foram observados empregando o extrato de raiz de ginseng e o ultrassom. O processo de emulsificação influenciou estatisticamente a estabilidade das emulsões
Abstract: The presented doctoral work is divided into two main themes under which one is about the use of supercritical technology for particle formation and the another one about the use of ultrasound for emulsion formulation. A literature review about the state of the art in using supercritical CO2 for micro and nanoparticles formation and encapsulation showed the potential of this technology. A homemade experimental apparatuses constructed by our research group and used for micro and nanoparticles formation has been validated using a model substance, the ibuprofen sodium salt. This drug was selected due to the literature information of the CO2-Ibuprofen system. The effect of operational conditions (temperature, pressure, CO2 flow rate, solution flow rate, injector and concentration of ibuprofen sodium in the ethanol solution) on the precipitation yield, energy consumption per unit of manufactured product, residual solvent content and particle morphology have been investigated using split-plot designs. Ibuprofen sodium salt was successfully micronized by Antisolvent Supercritical (SAS) using the constructed unit. The CO2 flow rate influenced the precipitation yield at statistically significant levels meanwhile none operating parameters did influence the residual solvent content in the micronized particles. Selecting appropriate process conditions, it has been shown to facilitate the production of homogeneous sheet-like microparticles of ibuprofen particles, the best for tableting purposes, with low residual solvent and high precipitation yield. In this work, the use of ultrasound has been also explored for fabricating microemulsion of 'delta'-tocotrienol-rich oil in order to add value to these extracts obtained from annatto seeds using supercritical extraction (SFE). The main pigments of annatto seeds are bixin and norbixin, wich are valuable natural colorants. However, these seeds have acquired notoriety by containing other important substances for human health, such as tocopherols, tocotrienols and geranylgeraniol. Due to the bioactive compounds importance, which have moisturizers, sunscreens and antioxidant properties, this study aimed to develop methods for emulsion formulation enabling the protection of these unstable compounds to adverse conditions, thus increasing the value of extracts from annatto seeds. Saponin-rich extract from Brazilian ginseng roots was used as biosurfactant. Additionally, emulsion was generated through mechanical stirring by dispax Reactor at the same energy density than ultrasound. The influence of the emulsification process, energy density, oil type, biosurfactant type and biosurfactant concentration on the size and stability of the resulting droplets was investigated. The results indicated that saponin-rich extract might be an attractive biosurfactant choice for emulsion formulations for use in food and beverage products. Mini-emulsions were obtained in this work; their droplet sizes ranged from 0.35 to 0.83 µm, saponin-rich extract and ultrasound gave the smallest droplet size. The emulsification process significantly affected the emulsion stability values
Doutorado
Engenharia de Alimentos
Doutora em Engenharia de Alimentos
Fobi, Kwabena, Bronson Lynn, and Abbas Gholipour Shilabin. "Extraction, Purification, and Characterization of Radioprotective Agent gamma-Tocotrienol Isomer in Palm Oil." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/asrf/2019/schedule/188.
Full textMuenyi, Christian Mbangha. "Vitamin E (Tocotrienols) and Prostate Cancer: A Proteomics Approach." Digital Commons @ East Tennessee State University, 2007. https://dc.etsu.edu/etd/2126.
Full textMoka, Nagaishwarya, Kelley cross, Marianne Brannon, Janet Lightner, Megan Dycus, William Stone, Victoria Palau, and Koyamangalath Krishnan. "Delta-tocotrienol and simvastatin induces differential cytotoxicity and synergy in BRAF wild-type SK-MEL-2 and mutant BRAF SK-MEL-28 melanoma cancer cells." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/asrf/2018/schedule/215.
Full textShipley, Lindsey C. BS, Harika MD Balagoni, Janet Lightner, Victoria PhD Palau, and Koyamangalath MD Krishnan. "15 Lox 1 Up-regulation and Cytotoxicity with γ-tocotrienol in HCT-116 Colon Cancer Cells." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/asrf/2018/schedule/154.
Full textLuk, Sze-ue. "The potential effect of bioactive food supplements in targeting prostate cancer stem cells." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43223795.
Full textBooks on the topic "Tocotrienol"
R, Watson Ronald, and Preedy Victor R, eds. Tocotrienols: Vitamin E beyond tocopherols. Boca Raton: Taylor & Francis, 2008.
Find full textTocotrienols: Vitamin E beyond tocopherols. 2nd ed. Boca Raton: CRC Press, 2013.
Find full textBourgeois, Claude. Determination of vitamin E: Tocopherols and tocotrienols. London: Elsevier Applied Science, 1992.
Find full textGu, Fan. Investigations towards the synthesis of isotope labelled analogues of tocopherols and tocotrienols. St. Catharines, Ont: Brock University, Dept. of Chemistry, 2006.
Find full textWatson, Ronald R., Victor R. Preedy, and Ronald Ross Watson. Tocotrienols: Vitamin E Beyond Tocopherols. Taylor & Francis Group, 2008.
Find full textFroemming, Gabriele, Abdul Manaf Ali, Hapizah Nawawi, and Suhaila Abd Muid. Pure Tocotrienols and Tocotrienol-Tocopherol Mixed Fraction As Anti-atherosclerotic Agents. Independently Published, 2018.
Find full textTan, Barrie, Ronald Ross Watson, and Victor R. Preedy, eds. Tocotrienols. CRC Press, 2012. http://dx.doi.org/10.1201/b12502.
Full textWatson, Ronald Ross, and Victor R. Preedy, eds. Tocotrienols. CRC Press, 2008. http://dx.doi.org/10.1201/9781420080391.
Full textAbdullah, Azman, and Ahmed Atia. Palm Oil-Derived Natural Vitamin E : ITS ROLE in CELLULAR PROTECTION and NRF2/KEAP1 SIGNALING: The Role of Tocotrienol-Rich Fraction of Palm Oil in Health Protection. Eliva Press, 2020.
Find full textWatson, Ronald R., Victor R. Preedy, and Barrie Tan. Tocotrienols: Vitamin e Beyond Tocopherols. Taylor & Francis Group, 2016.
Find full textBook chapters on the topic "Tocotrienol"
Nakagawa, Kiyotaka, Phumon Sookwong, and Teruo Miyazawa. "Tocotrienol Fortification in Eggs." In Handbook of Food Fortification and Health, 265–73. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-7076-2_21.
Full textBiswas, Nirupam, and Savita Khanna. "Tocotrienol Vitamin E and Neurodegenerative Disorders." In Antioxidants and Functional Foods for Neurodegenerative Disorders, 229–39. First edition. | Boca Raton : CRC Press, 2021.: CRC Press, 2020. http://dx.doi.org/10.1201/9780429319310-18.
Full textChin, Kok-Yong, Kok-Lun Pang, and Ima-Nirwana Soelaiman. "Tocotrienol and Its Role in Chronic Diseases." In Advances in Experimental Medicine and Biology, 97–130. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-41334-1_5.
Full textChopra, Kanwaljit, and Vinod Tiwari. "Tocotrienol and Cognitive Dysfunction Induced by Alcohol." In Alcohol, Nutrition, and Health Consequences, 181–202. Totowa, NJ: Humana Press, 2012. http://dx.doi.org/10.1007/978-1-62703-047-2_14.
Full textYamashita, K. "Dietary tocotrienol and UVB-induced skin damage." In Handbook of diet, nutrition and the skin, 164–77. Wageningen: Wageningen Academic Publishers, 2012. http://dx.doi.org/10.3920/978-90-8686-729-5_10.
Full textTeoh, M. K., M. K. Chong, and M. Jamaludin. "Effects of Tocotrienol-Rich Vitamin E on Patients with Peripheral Vascular Disease." In Lipid-Soluble Antioxidants: Biochemistry and Clinical Applications, 606–21. Basel: Birkhäuser Basel, 1992. http://dx.doi.org/10.1007/978-3-0348-7432-8_48.
Full textSylvester, Paul W. "The Role of Lipid Rafts in Mediating the Anticancer Effects of γ-Tocotrienol." In Vitamin E in Human Health, 125–40. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-05315-4_10.
Full textHayes, K. C., A. Pronczuk, J. S. Liang, and S. Lindsey. "Tocopherol and Tocotrienol Plasma Transport and Tissue Concentrations: Implications for Their Relative Biological Functions." In Lipid-Soluble Antioxidants: Biochemistry and Clinical Applications, 105–22. Basel: Birkhäuser Basel, 1992. http://dx.doi.org/10.1007/978-3-0348-7432-8_10.
Full textGhosh, Sanchita, Martin Hauer-Jensen, and K. Sree Kumar. "Gamma-Tocotrienol." In Tocotrienols, 379–98. CRC Press, 2008. http://dx.doi.org/10.1201/9781420080391.ch27.
Full textPilolli, Francesca, Marta Piroddi, Elisa Pierpaoli, Silvia Ciffolilli, Mauro Provinciali, and Francesco Galli. "δ-Tocotrienol." In Tocotrienols, 117–34. CRC Press, 2012. http://dx.doi.org/10.1201/b12502-10.
Full textConference papers on the topic "Tocotrienol"
Shaharom, R. R. S., M. N. Nayan, M. M. N. Radzi, R. Akbar, and S. A. Jusoh. "Molecular docking study of a tocotrienol and P-glycoprotein." In 2013 IEEE Symposium on Computers & Informatics (ISCI). IEEE, 2013. http://dx.doi.org/10.1109/isci.2013.6612393.
Full textNasibah, A., M. H. Rajikin, M. N. K. Nor-Ashikin, and A. S. Nuraliza. "Tocotrienol improves the quality of impaired mouse embryos induced by corticosterone." In 2012 IEEE Colloquium on Humanities, Science and Engineering Research (CHUSER). IEEE, 2012. http://dx.doi.org/10.1109/chuser.2012.6504297.
Full textFayyad, Ahmed Abu, Mohammad Kamal, Amal Kaddoumi, Saeed Alqahtani, and Sami Nazzal. "PEGylation Enhances the Oral Bioavailability of γ-Tocotrienol Isomer of Vitamin E." In 2016 32nd Southern Biomedical Engineering Conference (SBEC). IEEE, 2016. http://dx.doi.org/10.1109/sbec.2016.26.
Full textTiwari, RV, P. Parajuli, and PW Sylvester. "Abstract P3-03-12: Gamma-tocotrienol induces autophagy in malignant mammary tumor cells." In Abstracts: Thirty-Sixth Annual CTRC-AACR San Antonio Breast Cancer Symposium - Dec 10-14, 2013; San Antonio, TX. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/0008-5472.sabcs13-p3-03-12.
Full textChakraborty, Kanishka, Victoria P. Ramsauer, Janet W. Lightner, William L. Stone, and Koyamangalath Krishnan. "Abstract 2106: Gamma-tocotrienol upregulates the ceramide transporter, Arv-1, in pancreatic cancer cells." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-2106.
Full textAkl, Mohamed R., Bilal Abuasal, Amal Kaddoumi, and Paul W. Sylvester. "Abstract 3045: Sesamin synergistically potentiates the anticancer effects of γ-tocotrienol in mammary tumor cells." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-3045.
Full textHusain, Kazim, Said M. Sebti, and Mokenge P. Malafa. "Abstract 1098: Delta-tocotrienol chemosensitizes human pancreatic tumor metastasis to gemcitabine targeting cancer stem cells." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-1098.
Full textGopalan, Archana, Weiping Yu, Bob G. Sanders, and Kimberly Kline. "Abstract 4223: Gamma-tocotrienol and simvastatin target TIC and EMT populations in drug-resistant breast cancer." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-4223.
Full textPimiento, Jose M. "Abstract 1630: Vitamin E delta-tocotrienol prevents azoxymethane-induced colon carcinogenesis progression in Fisher-344 rats." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-1630.
Full textMoore, Christine A., Janet W. Lightner, Michelle Duffourc, and Koyamangalath Krishnan. "Abstract 3977: γ-Tocotrienol and metformin are cytotoxic to prostate cancer cell lines and exhibit synergy." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-3977.
Full textReports on the topic "Tocotrienol"
Stone, William L., K. Krishnan, and Sharon Campbell. Tocotrienols and Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, September 2005. http://dx.doi.org/10.21236/ada453328.
Full textLampi, Anna-Maija. Analysis of Tocopherols and Tocotrienols by HPLC. AOCS, August 2011. http://dx.doi.org/10.21748/lipidlibrary.40389.
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