Academic literature on the topic 'Tissue-on-chip'
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Journal articles on the topic "Tissue-on-chip"
Narciso, Cody, Kyle R. Cowdrick, Victoria Zellmer, Teresa Brito-Robinson, Pavel Brodskiy, David J. Hoelzle, Siyuan Zhang, and Jeremiah J. Zartman. "On-chip three-dimensional tissue histology for microbiopsies." Biomicrofluidics 10, no. 2 (March 2016): 021101. http://dx.doi.org/10.1063/1.4941708.
Full textDorrigiv, Dina, Kayla Simeone, Laudine Communal, Jennifer Kendall-Dupont, Amélie St-Georges-Robillard, Benjamin Péant, Euridice Carmona, Anne-Marie Mes-Masson, and Thomas Gervais. "Microdissected Tissue vs Tissue Slices—A Comparative Study of Tumor Explant Models Cultured On-Chip and Off-Chip." Cancers 13, no. 16 (August 21, 2021): 4208. http://dx.doi.org/10.3390/cancers13164208.
Full textTavakol, Daniel Naveed, Sharon Fleischer, and Gordana Vunjak-Novakovic. "Harnessing organs-on-a-chip to model tissue regeneration." Cell Stem Cell 28, no. 6 (June 2021): 993–1015. http://dx.doi.org/10.1016/j.stem.2021.05.008.
Full textAuthasing, S., S. Chantanetra, S.Mitatha, and P. P. Yupapin. "Tissue Culture On-chip Design using Multivariable Molecular Network." Procedia Engineering 32 (2012): 286–90. http://dx.doi.org/10.1016/j.proeng.2012.01.1269.
Full textWANG, Wei-Xin, Wei-Ping LIU, Bin WU, Guang-Tie LIANG, and Da-Yu LIU. "Construction of Tumor Tissue Microarray on a Microfluidic Chip." Chinese Journal of Analytical Chemistry 43, no. 5 (May 2015): 637–42. http://dx.doi.org/10.1016/s1872-2040(15)60823-4.
Full textHaim, Yulia, Tanya Tarnovscki, Dana Bashari, and Assaf Rudich. "A chromatin immunoprecipitation (ChIP) protocol for use in whole human adipose tissue." American Journal of Physiology-Endocrinology and Metabolism 305, no. 9 (November 1, 2013): E1172—E1177. http://dx.doi.org/10.1152/ajpendo.00598.2012.
Full textNitsche, Katharina S., Iris Müller, Sophie Malcomber, Paul L. Carmichael, and Hans Bouwmeester. "Implementing organ-on-chip in a next-generation risk assessment of chemicals: a review." Archives of Toxicology 96, no. 3 (February 1, 2022): 711–41. http://dx.doi.org/10.1007/s00204-022-03234-0.
Full textMoradi, Ehsanollah, Sasan Jalili-Firoozinezhad, and Mehran Solati-Hashjin. "Microfluidic organ-on-a-chip models of human liver tissue." Acta Biomaterialia 116 (October 2020): 67–83. http://dx.doi.org/10.1016/j.actbio.2020.08.041.
Full textZoio, Patrícia, Sara Lopes-Ventura, and Abel Oliva. "Barrier-on-a-Chip with a Modular Architecture and Integrated Sensors for Real-Time Measurement of Biological Barrier Function." Micromachines 12, no. 7 (July 12, 2021): 816. http://dx.doi.org/10.3390/mi12070816.
Full textSateesh, Jasti, Koushik Guha, Arindam Dutta, Pratim Sengupta, Dhanya Yalamanchili, Nanda Sai Donepudi, M. Surya Manoj, and Sk Shahrukh Sohail. "A comprehensive review on advancements in tissue engineering and microfluidics toward kidney-on-chip." Biomicrofluidics 16, no. 4 (July 2022): 041501. http://dx.doi.org/10.1063/5.0087852.
Full textDissertations / Theses on the topic "Tissue-on-chip"
Rathbone, Daniel Rodion. "A low volume oxygenator for open well Liver-on-a-Chip tissue culture." Thesis, Massachusetts Institute of Technology, 2018. http://hdl.handle.net/1721.1/120193.
Full textThis electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Cataloged from student-submitted PDF version of thesis.
Includes bibliographical references (pages 139-142).
MicroPhysiological Systems (MPS) show significant promise in speeding drug development and advancing basic research. They may serve better than animal models for obtaining accurate human response data and thereby reducing failed clinical trials. The CN Bio LiverChip is one such commercial MPS device which cultures liver cells on a perforated polystyrene scaffold and actively circulates cell culture medium through them. Reducing the total circulating volume is desirable to increase the concentration of difficult-to-detect compounds, improve autocrine signaling, and achieve more physiologically relevant drug decay times. However, achieving adequate oxygenation at lower volumes is challenging due to surface tension effects. This thesis describes an open-well, flow-through MPS platform with a low-volume oxygenator, at a total circulating volume of approximately 500 [mu]L. The oxygenator uses the interior corner of a hydrophilic spiral to constrain the circulating fluid and to create a thin fluid region, which decreases the diffusion depth relative to exposed surface area, thereby improving oxygenation. The oxygenator performs equivalently to the LiverChip at a fraction of the volume, and features a downward slope that prevents fluid from accumulating in the oxygenator, which could deplete the cell culture well. The fluidic configuration and other design considerations are described, as well as hardware testing results and improved methods for preventing fluid from bypassing the scaffold. This project was supported by NIH grant number UH3-TR000496.
by Daniel Rodion Rathbone.
S.M.
Minier, Nicolas. "Development of an organ-on-chip microfluidic device incorporating an actuatable hydrogel layer to produce barrier tissue mimicries on chips." Thesis, Compiègne, 2021. https://bibliotheque.utc.fr/Default/doc/SYRACUSE/2021COMP2644.
Full textModern day ethics and laws call for more safety and use of fewer animals in biomedical research. It became crucial to develop novel in vitro devices of higher relevance. Since the end of the twentieth century, several systems have been proposed by researchers in attempts to palliate the shortcomings of current systems. Notably, organs-on-chip systems are specifically tailored to recapitulate tissue functions in a manner that remains easily accessible for the experimenter. Despite the significant improvements that were brought during the last century to in vitro cell and tissue culture systems, the field of bioengineering is still young and much progress remains to be done. The work presented here details the development of an organ-on-chip that includes a biocompatible and actuatable hydrogel membrane, with controlled physico-chemical properties. Such chip is relevant when hosting barrier tissues, which are composed of several cell types, disposed on each side of a barrier, as well as within its bulk, and are often submitted to mechanical stimuli. During this PhD, several objectives have been attained. Notably, we: - Designed and produced an organ-on-chip including a biocompatible and actuatable hydrogel layer, as well as a microfluidic system allowing the independent control of both flow and actuation. - Characterized the deformation of the hydrogel layer. - Cultured intestinal cells within the chip, which formed a three dimensionally structure epithelium, and characterized its apparent permeability to molecules of varying sizes
Sivaraman, Anand 1977. "A microfabricated 3D tissue engineered "Liver on a Chip" : information content assays for in vitro drug metabolism studies." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/28661.
Full textIncludes bibliographical references (p. 180-195).
(cont.) approaches to improving hepatocyte function in culture have been described, not all of the important functions--specifically the biotransformation functions of the liver--can as yet be replicated at desired in ivo levels, especially in culture formats amenable to routine use in drug development. The in vivo microenvironment of hepatocytes in the liver capillary bed includes signaling mechanisms mediated by cell-cell and cell-matrix interactions, soluble factors, and mechanical forces. This thesis focuses on the design, fabrication, modeling and characterization of a microfabricated bioreactor system that attempts to mimic the in vivo microenvironment by allowing for the three dimensional morphogenesis of liver tissue under continuous perfusion conditions. A key feature of the bioreactor that was designed is the distribution of cells into many tiny ([approximately]0.001 cm³) tissue units that are uniformly perfused with culture medium. The total mass of tissue in the system is readily adjusted for applications requiring only a few thousand cells to those requiring over a million cells by keeping the microenvironment the same and scaling the total number of tissue units in the reactor. Using a computational fluid dynamic model in ADINA® and a species conservation mass transfer model in FEMLAB®, the design of the bioreactor and the fluidic circuit was optimized to mimic physiological shear stress rates ...
Recent reports indicate that it takes nearly $800 million dollars and 10-15 years of development time to bring a drug to market. The pre-clinical stage of the drug development process includes a panel of screens with in vitro models followed by comprehensive studies in animals to make quantitative and qualitative predictions of the main pharmacodynamic, pharmacokinetic, and toxicological properties of the candidate drug. Nearly 90% of the lead candidates identified by current in vitro screens fail to become drugs. Among lead compounds that progress to Phase I clinical trials, more than 50% fail due to unforeseen human liver toxicity and bioavailability issues. Clearly, better methods are needed to predict human responses to drugs. The liver is the most important site of drug metabolism and a variety of ex vivo and in vitro model systems have therefore been developed to mimic key aspects of the in vivo biotransformation pathways of human liver-- a pre-requisite for a good, predictive pharmacologically relevant screen. Drug metabolism or biotransformation in the liver involves a set of Phase I (or p450 mediated) and Phase II enzyme reactions that affect the overall therapeutic and toxic profile of a drug. The liver is also a key site of drug toxicity following biotransformation, a response that is desirable but difficult to mimic in vitro. A major barrier to predictive liver metabolism and toxicology is the rapid (hours) loss of liver-specific functions in isolated hepatocytes when maintained under standard in itrom cell culture condition. This loss of function may be especially important in predicting toxicology, where the time scale for toxic response may greatly exceed the time scale for loss of hepatocyte function in culture. Although a wide variety of
by Anand Sivaraman.
Ph.D.
Boulais, Lilandra. "Cryogel-integrated hepatic cell culture microchips for liver tissue engineering." Thesis, Compiègne, 2020. http://www.theses.fr/2020COMP2561.
Full textToday, one of the challenges for the pharmaceutical industry is to develop accurate in vitro liver models to improve the predictability of preclinical studies, in particular the study of the toxicity and efficacy of drug candidates. In recent years, tissue engineering, a multidisciplinary approach to develop tissues, has led to the development of new cell culture methods. Among them, cell cultures in 3D or in perfusion allowed to obtain hepatic activities similar to those observed in vivo. The objective of this thesis is to combine these two cell culture methods to create an even more accurate in vitro liver model. To do so, we are seeking to develop an alginate cryogel integrated into a microchip with mechanical properties adaptable to those of the liver depending on the physiological state to be reproduced (healthy or pathological liver).In the first part, we develop and characterize the alginate cryogel at the microscopic and macroscopic level, outside (cylindrical samples) and then inside the biochip. Three parameters are studied here: the cryopolymerization temperature, the alginate concentration and the quantity of cross-linking agents. Mechanical properties, porosity, absorption, pore interconnectivity and flow resistance are analyzed. The second part aims to culture liver cells within this new device. For this feasibility study the HepG2/C3A cell line is used. The results show viable and functional cells (albumin production, APAP transformation). In addition, we observe a 3D tissue structure, which is maintained after removal of the alginate cryogel. The last part aims to complexify the hepatic model, in particular by co-cultures. To get closer to the sinusoid structure, liver cells are cultured with endothelial cells (HUVEC) according to two approaches. In addition, the possibility to follow circulating tumor cells (MDA-MB-231) in the system is studied
Krammer, Thibault. "Développement d'un réseau microvasculaire sur puce microfluidique pour la reconstruction tissulaire." Thesis, Université Grenoble Alpes (ComUE), 2019. http://www.theses.fr/2019GREAV044.
Full textTissue engineering aims to develop functional tissues or organs in vitro in order to provide drug testing platforms or transplantable tissues and improve the treatments provided to patients. However, the physiological tissue structures developed to date do not integrate and perfusable vascular network. In vivo, the vascular network supplies the body’s cells with oxygen and nutrients and removes cellular waste and carbon dioxide. It also has a major role in maintaining organ homeostasis. Blood capillaries are hollow vessels whose walls are only composed of a layer of endothelial cells and diffuse nutrients. The blood capillary network is dense and perfuse all tissues. Due to the limit oxygen diffusion inside tissues, each cell is located at most 200µm away from a capillary. The difficulties of building a network of perfusable capillaries and integrating them into tissue constructs limit the development of thick physiological tissues.An innovative technique for developing a microvascular network within a thick construction is presented in this thesis. This technique consists of assembling spherical tissue micro-units within a microfluidic chamber, and developing a network of capillaries through the interstitial pores formed by the spheres packing. Tissue micro-units are composed of biopolymers representative of the extracellular matrix and contain cells from the tissue of interest. A layer of endothelial cells is developed on the surface of these microspheres. The stacking of these microspheres creates a porous medium in which nutrient medium is perfused. Flow control within such a structure allows the application of physical stimuli influencing the self-assembly of endothelial cells into capillaries within the interstitial space of the sphere packing.During this thesis, a device for manufacturing microspheres from natural biopolymers was developed. The structure formed by the stacks of spheres was studied and the flow within such environments were characterized so as to apply controlled physical stimuli to cells. A bioreactor-like perfusion system has been built. A thick tissue structure could be formed within this system and the development of the vascular network was promoted. The formation of the network was demonstrated by the presence of infused blood capillaries within the structure. The technique developed promises to be applied to the development of many tissues and applications for organ-on-chip or tissue engineering devices
Essaouiba, Amal. "Development of a liver-pancreas in vitro model using microfluidic organ-on-chip technologies." Thesis, Compiègne, 2020. http://www.theses.fr/2020COMP2573.
Full textDiabetes mellitus (DM) or the so called disease of the century is a life threatening dysfunction that affects the endocrine system. The mechanisms underlying the break in the feedback loop that regulates the metabolism and the consequent diabetes induction are not fully known. Understanding the mechanisms of insulin action is therefore crucial for the further development of effective therapeutic strategies to combat DM. Accordingly, it is imperative to find a robust and reliable model for diabetes research able to overcome the limitations of traditional 2D in vitro cell culture and animal experimentation. The aim of this thesis is to develop a new liver‐pancreas co‐culture model using advanced microphysiological systems (MPs) to tackle more effectively the mechanism involving the hepatic and pancreatic endocrine regulation. This work highlights the power of multi organ‐on‐chip systems that combines the advanced 3D‐cell compartmentalization, microfluidics and induced pluripotent stem cells (iPSC) technology to achieve a high biological complexity and functions that are rarely reproduced by only one of these tissue engineering technologies
Shah, Pratikkumar. "Development of a Lab-on-a-Chip Device for Rapid Nanotoxicity Assessment In Vitro." FIU Digital Commons, 2014. http://digitalcommons.fiu.edu/etd/1834.
Full textCarvalho, Mariana Rodrigues de. "Tissue engineered in vitro models on a chip for cancer research." Doctoral thesis, 2019. http://hdl.handle.net/1822/64605.
Full textBy 2030, the global burden is expected to grow to 21.7 million new cancer cases and 13 million cancer deaths simply due to the growth and aging of the population. Among all types of cancer, colorectal cancer is a major cause of morbidity and mortality worldwide, and accounts for over 9 % of all cancer incidence. It is the third most common cancer worldwide and affects men and women equally. In order to win the battle against cancer, further advances are in great need to unveil identification of cancer-causing agents in in vitro and in vivo animal models, as well as for the development of personalized therapies, drug screening, and to provide insightful knowledge on the mechanisms of tumor growth and metastasis. Microfluidic devices, together with tissue engineering strategies and nanotechnology have emerged as a powerful platform to tackle the previously mentioned hurdles. These themes are the focus of Section 1, in Chapters I, II and III. In this thesis we focus on the application of CMCht/PAMAM dendrimer nanoparticles.as the synthesis, uptake efficiency/internalization and cytotoxic effect of fluorescent-labeled CMCht/PAMAM dendrimer nanoparticles was investigated using different cancer cell lines in both traditional culture flasks and under physiological flow inside a microfluidic platform (Chapter V). Other than nanoparticles, the use of different biomaterials to modulate 3D microenvironment of tumors is of the utmost importance. Therefore, the use of HRP-crosslinked SF hydrogels with spatial tunable properties was proposed in a colorectal cancer extravasation 3D model on a commercial chip Vena4™ (Chapter VI). To increase the complexity of the cancer models, a microfluidic chip was designed and fabricated for the incorporation of tumor and vascular parts, allowing for gradients of gemcitabine released from CMCht/PAMAM nanoparticles to be tested (Chapter VII). Chemical modification in the CMCht/PAMAM dendrimer nanoparticles in order to target colorectal cancer was also achieved in Chapter VIII. In Chapter IX, a new proof of concept consisting of a microfluidic silk platform, flexible and implantable, was developed in house. The results and platforms developed in this thesis are discussed in Chapter X and represent a strong advance in the field of lab-on-chip research and will be a useful tool for drug discovery and study of migration/metastasis phenomena, allowing for a versatile choice of tissues, biomaterials and biological assays.
Até 2030, o número global de novos casos de cancro deverá crescer para 21,7 milhões, com cerca de 13 milhões de mortes, simplesmente devido ao crescimento e envelhecimento da população. Entre todos os tipos de cancro, o cancro colorretal é uma das principais causas de morbidade e mortalidade em todo o mundo, representando mais de 9 % entre todos os tipos de cancro. Com o objectivo de ganhar a guerra contra o cancro, novos avanços são rapidamente precisos, a fim de identificar, em modelos animais in vitro e in vivo os agentes causadores de cancro, bem como para o desenvolvimento de terapias personalizadas, teste de novos fármacos e aumentar o conhecimento actual sobre os mecanismos de crescimento tumoral e metástases. Dispositivos de microfluídica juntamente com estratégias de engenharia de tecidos e nanotecnologia surgiram como uma poderosa plataforma para lidar com os obstáculos mencionados anteriormente. Esses temas são o foco da Secção 1, nos Capítulos I, II e III. Nesta tese damos enfâse à aplicação de nanopartículas CMCht/PAMAM. A síntese, eficiência, internalização e efeito citotóxico das mesmas foram investigados usando diferentes linhas de células tumorais em frascos de cultura tradicionais e dentro de uma plataforma microfluídica (Capítulo V). Além das nanopartículas, o uso de diferentes biomateriais para modular o microambiente 3D de tumores é de extrema importância. Portanto, o uso de hidrogéis SF reticulados com HRP com propriedades mecânicas ajustáveis foi proposto num modelo 3D de extravasamento de cancro colorretal num chip comercial VenaT4™ (Capítulo VI). Para aumentar a complexidade dos modelos de cancro em chips, uma plataforma microfluídica foi projetada e fabricada para a incorporação de ambas as partes tumorais e vasculares, permitindo testar gradientes de gemcitabina libertados das nanopartículas CMCht/PAMAM (Capítulo VII). Modificações químicas nas nanopartículas para atingir especificamente células cancerígenas também foram alcançadas no Capítulo VIII. No Capítulo IX, uma nova prova de conceito consistindo numa plataforma microfluídica de seda, totalmente flexível e implantável, foi desenvolvida. Os resultados e plataformas desenvolvidos nesta tese representam um forte avanço no campo da investigação do cancro, e serão uma ferramenta útil para a descoberta de drogas e estudo de metastases, permitindo uma escolha versátil de tecidos, hidrogéis e ensaios biológicos.
"Engineering an integrated microphysiological system for modeling human fibrotic disease." Tulane University, 2021.
Find full textFibrotic diseases comprise up to 45% of deaths in the industrialized world. Few effective anti-fibrotic therapeutics exist, due in part to the lack of human-relevant preclinical models. The goal of this research was to improve the modeling of fibrotic diseases in microphysiological systems (MPS) by engineering quiescence in cultured human fibroblasts prior to MPS incorporation. To create an assay for testing this approach, a versatile organ chip was designed while optimizing workflow for production of the organ chip molds with an SLA 3D printer. After identifying 2D culture conditions that repress fibroblast activation, we tested the hypothesis that the 2D culture protocol would impact the fibrotic baseline in our MPS. 3D confocal microscopy and multi-metric image analysis of immunostaining for cellular and extracellular matrix (ECM) components via intensity and pattern quantification revealed the establishment of more physiological baseline for MPS fibrosis models. To test in a disease-relevant context, we created a model of the stromal reaction in lung cancer using our organ chip and demonstrated that our integrated MPS can be used to quantify the fibrosis-inducing effects of cancer cells that drive stromal reactions.
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Max Wendell
Javor, Josh. "BioMEMS for cardiac tissue monitoring and maturation." Thesis, 2021. https://hdl.handle.net/2144/42600.
Full text2022-05-15T00:00:00Z
Books on the topic "Tissue-on-chip"
Ramadan, Qasem, Massimo Alberti, Martin Dufva, and Yi-Chung Tung, eds. Medical and Industrial Applications of Microfluidic-based Cell/Tissue Culture and Organs-on-a-Chip: Advances in Organs-on-a-Chip and Organoids Technologies. Frontiers Media SA, 2019. http://dx.doi.org/10.3389/978-2-88963-114-8.
Full textLepora, Nathan F. Biohybrid systems. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780199674923.003.0048.
Full textBook chapters on the topic "Tissue-on-chip"
Morimoto, Yuya, Nobuhito Mori, and Shoji Takeuchi. "In Vitro Tissue Construction for Organ-on-a-Chip Applications." In Bioanalysis, 247–74. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-6229-3_9.
Full textWang, Zongjie, Roya Samanipour, and Keekyoung Kim. "Organ-on-a-Chip Platforms for Drug Screening and Tissue Engineering." In Biomedical Engineering: Frontier Research and Converging Technologies, 209–33. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-21813-7_10.
Full textYoon, Jeong-Yeol. "Organ-on-a-Chip." In Tissue Engineering, 193–217. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-83696-2_11.
Full textTong, Ziqiu, Wing-Yin Tong, Bo Peng, Yingkai Wei, Arianna Oddo, and Nicolas H. Voelcker. "Using Integrated Cancer-on-Chip Platforms to Emulate and Probe Various Cancer Models." In Nanotechnology Characterization Tools for Tissue Engineering and Medical Therapy, 151–204. Berlin, Heidelberg: Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-59596-1_4.
Full textAboutalebianaraki, Nadia, Angela Shar, Madisyn Messmore, Kaylee Misiti, and Mehdi Razavi. "Musculoskeletal tissue-on-a-chip." In Principles of Human Organs-on-Chips, 407–28. Elsevier, 2023. http://dx.doi.org/10.1016/b978-0-12-823536-2.00010-9.
Full textDouglas, Kenneth. "Organs-on-a-Chip." In Bioprinting, 155–82. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780190943547.003.0010.
Full textShupe, Thomas, Aleksander Skardal, and Anthony Atala. "Body-on-a-chip: three-dimensional engineered tissue models." In Principles of Tissue Engineering, 1443–58. Elsevier, 2020. http://dx.doi.org/10.1016/b978-0-12-818422-6.00078-2.
Full textPappalardo, Alberto, Alvarez Cespedes, Ha Linh Vu, and Hasan Erbil Abaci. "Advances in skin-on-a-chip and skin tissue engineering." In Principles of Human Organs-on-Chips, 123–66. Elsevier, 2023. http://dx.doi.org/10.1016/b978-0-12-823536-2.00005-5.
Full textÇakır Hatır, Pınar. "Biomedical Nanotechnology." In Research Anthology on Emerging Technologies and Ethical Implications in Human Enhancement, 634–62. IGI Global, 2021. http://dx.doi.org/10.4018/978-1-7998-8050-9.ch033.
Full textÇakır Hatır, Pınar. "Biomedical Nanotechnology." In Biomedical and Clinical Engineering for Healthcare Advancement, 30–65. IGI Global, 2020. http://dx.doi.org/10.4018/978-1-7998-0326-3.ch003.
Full textConference papers on the topic "Tissue-on-chip"
Goyal, Girija, Jaclyn Long, and Donald E. Ingber. "Abstract A76: Microenginered human lymphoid tissue on chip." In Abstracts: AACR Special Conference on Tumor Immunology and Immunotherapy; October 1-4, 2017; Boston, MA. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/2326-6074.tumimm17-a76.
Full textPoulikakos, L. V., S. Bordy, J. Byun, Z. Haddadin, P. Kirya, S. Khan, D. Y. Kim, et al. "Colorimetric Metasurfaces for Quantitative, On-Chip Tissue Diagnostics." In CLEO: Science and Innovations. Washington, D.C.: Optica Publishing Group, 2022. http://dx.doi.org/10.1364/cleo_si.2022.sth5j.7.
Full textZhang, Yibo, Yoonjung Shin, Kevin Sung, Sam Yang, Harrison Chen, Hongda Wang, Da Teng, et al. "3D on-chip microscopy of optically cleared tissue." In Optics and Biophotonics in Low-Resource Settings IV, edited by David Levitz, Aydogan Ozcan, and David Erickson. SPIE, 2018. http://dx.doi.org/10.1117/12.2290558.
Full textJin, Laidi, Tian Tian, Danyang Liu, Hongjv Mao, and Huiying Liu. "·Reconstituting Organ-Level Periodontal Soft Tissue on a Chip." In 2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers). IEEE, 2021. http://dx.doi.org/10.1109/transducers50396.2021.9495506.
Full textOkino, Yuki, Toshifumi Asano, and Keisuke Morishima. "Molecular dynamics of orientation controlled muscle tissue on a chip." In 2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS). IEEE, 2015. http://dx.doi.org/10.1109/mhs.2015.7438346.
Full textBalciunas, Evaldas, Linas Jonusauskas, Vytautas Valuckas, Daiva Baltriukiene, Virginija Bukelskiene, Roaldas Gadonas, and Mangirdas Malinauskas. "Lithographic microfabrication of biocompatible polymers for tissue engineering and lab-on-a-chip applications." In SPIE Photonics Europe, edited by Jürgen Popp, Wolfgang Drexler, Valery V. Tuchin, and Dennis L. Matthews. SPIE, 2012. http://dx.doi.org/10.1117/12.923042.
Full textWoon Tiong Ang, Changhong Yu, Jie Chen, Tarek El-Bialy, Michael Doschak, Hasan Uludag, and Ying Tsui. "System-on-chip ultrasonic transducer for dental tissue formation and stem cell growth and differentiation." In 2008 IEEE International Symposium on Circuits and Systems - ISCAS 2008. IEEE, 2008. http://dx.doi.org/10.1109/iscas.2008.4541793.
Full textDias, R. A., J. H. Correia, and G. Minas. "On-Chip Integrated Optical Sensors for Fluorescence Detection of Cancer Tissue: Application to Capsule Endoscopy." In 2007 14th IEEE International Conference on Electronics, Circuits and Systems (ICECS '07). IEEE, 2007. http://dx.doi.org/10.1109/icecs.2007.4511020.
Full textYoo, Kyoung Min, and Ray T. Chen. "On-Chip Si3N4 Spatial Heterodyne Fourier Transform Spectrometer for the Optical Window in Biological Tissue." In CLEO: Applications and Technology. Washington, D.C.: OSA, 2021. http://dx.doi.org/10.1364/cleo_at.2021.jtu3a.122.
Full textTourlomousis, Filippos, and Robert C. Chang. "Computational Modeling of 3D Printed Tissue-on-a-Chip Microfluidic Devices as Drug Screening Platforms." In ASME 2014 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/imece2014-38454.
Full textReports on the topic "Tissue-on-chip"
Eshed-Williams, Leor, and Daniel Zilberman. Genetic and cellular networks regulating cell fate at the shoot apical meristem. United States Department of Agriculture, January 2014. http://dx.doi.org/10.32747/2014.7699862.bard.
Full textGinzberg, Idit, and Walter De Jong. Molecular genetic and anatomical characterization of potato tuber skin appearance. United States Department of Agriculture, September 2008. http://dx.doi.org/10.32747/2008.7587733.bard.
Full text