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Academic literature on the topic 'Tissue Bank'

Author: Grafiati

Published: 4 June 2021

Last updated: 20 February 2023

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Journal articles on the topic "Tissue Bank"

Narayan, R. P. "Development of tissue bank." Indian Journal of Plastic Surgery 45, no. 02 (May 2012): 396–402. http://dx.doi.org/10.4103/0970-0358.101326.

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ABSTRACTThe history of tissue banking is as old as the use of skin grafting for resurfacing of burn wounds. Beneficial effects of tissue grafts led to wide spread use of auto and allograft for management of varied clinical conditions like skin wounds, bone defects following trauma or tumor ablation. Availability of adequate amount of tissues at the time of requirement was the biggest challenge that forced clinicians to find out techniques to preserve the living tissue for prolonged period of time for later use and thus the foundation of tissue banking was started in early twentieth century. Harvesting, processing, storage and transportation of human tissues for clinical use is the major activity of tissue banks. Low temperature storage of processed tissue is the best preservation technique at present. Tissue banking organization is a very complex system and needs high technical expertise and skilled personnel for proper functioning in a dedicated facility. A small lapse/deviation from the established protocol leads to loss of precious tissues and or harm to recipients as well as the risk of transmission of deadly diseases and tumors. Strict tissue transplant acts and stringent regulations help to streamline the whole process of tissue banking safe for recipients and to community as whole.

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Bilić, Katarina, Marija Vilaj, Branka Golubić-Ćepulić, and Davor Ježek. "Ovarian tissue bank." Croatian Medical Journal 62, no. 3 (June 2021): 297–99. http://dx.doi.org/10.3325/cmj.2021.62.297.

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Fricke, Hans. "Coelacanth tissue bank." Nature 357, no. 6374 (May 1992): 105. http://dx.doi.org/10.1038/357105b0.

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Edgerton, Mary E., Carl Morrison, Virginia A. LiVolsi, Christopher A. Moskaluk, Stephen J. Qualman, M. Kay Washington, and William E. Grizzle. "A Standards based Ontological Approach to Information Handling for use by Organizations Providing Human Tissue for Research." Cancer Informatics 6 (January 2008): 117693510800600. http://dx.doi.org/10.1177/117693510800600003.

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Tissue resources have become an important component of the infrastructure of institutions as well as companies performing biomedical research. Such tissue resources may be in the model of a bank, collecting a limited type of tissues and processing and storing them following a specific protocol. Such banks or archives may be associated with a clinical study or may function indepedently. An alternative type of tissue resource is utilized by many institutions and cancer centers. In this model, the investigator specifies the methods by which selected tissues are to be collected, processed and stored. In such a “prospective model”, initially developed at the University of Alabama at Birmingham and the Ohio State University in the late 1970's and adopted by the Cooperative Human Tissue Network in 1986, specific types of tissues are not collected unless requested by an investigator. At some sites, both a prospective and an archival (bank) model are followed. This article describes an informatics approach needed to support a prospective tissue resource. It is by necessity more complicated than a model which supports a tissue bank but also can be used by a tissue bank. Of great importance is the approach to vocabulary and common data elements needed to support the informatics system of a prospective tissue resource, especially if the informatics system is to be used by a variety of personnel with greatly varying educational backgrounds.

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Menter, Alan, Anne Bowcock, Laura Morris, Alan Silverman, Jo-Ann See, Melodie Young, Laura Kuykendall, Janda Hairston, and Detra Lory. "National Psoriasis Tissue Bank." Baylor University Medical Center Proceedings 8, no. 2 (April 1995): 14. http://dx.doi.org/10.1080/08998280.1995.11929911.

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van Veen, Ben-Evert. "Human tissue bank regulations." Nature Biotechnology 24, no. 5 (May 1, 2006): 496–97. http://dx.doi.org/10.1038/nbt0506-496.

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Tettamanti, Massimo, Sara Tralamazza, Marina Berati, Max Molteni, and Natascia Gamba. "Human Research Tissue Banks: The ATRA Project for Establishing a Human Research Tissue Bank in Switzerland." Alternatives to Laboratory Animals 33, no. 1 (February 2005): 29–36. http://dx.doi.org/10.1177/026119290503300106.

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A large number of experiments in biomedical research are carried out on tissues, but, even though the results should be applicable to humans, these tissues are mainly of animal origin. The difficulty encountered in obtaining human organs and tissues is an acknowledged problem: not enough human tissues are available to meet research needs. We are introducing the ATRA Project, with the purpose of supporting progress in biomedical research in Switzerland through the establishment of one or more human tissue banks, which will be able to find, treat, preserve and supply human material. Where similar projects have already been launched, concerns have been expressed that donation for research purposes might compete with donation for transplantation, but most organs and tissues are in any case non-transplantable. Surplus surgical tissue is considered “sanitary waste”, and must be treated according to specific regulations for collection, packaging, transport, treatment and disposal. A human tissue bank would not only abate the costs of treating sanitary waste, but would actually turn what is now considered waste into a resource which could be used to save human and animal lives.

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Linden, Jeanne V., and Thomas J. Favreau. "Professional Standards in Cell and Tissue Processing." Cell Transplantation 4, no. 5 (September 1995): 441–46. http://dx.doi.org/10.1177/096368979500400505.

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In the United States, standards for cell and tissue processing have been developed by a variety of professional tissue banking organizations. Several organizations, including the American Association of Tissue Banks and the Eye Bank Association of America, have accreditation programs for member institutions. Some governmental agencies, such as the New York State Department of Health and the Food and Drug Administration, have adopted strict regulations, which may subject noncompliant tissue banks to certain enforcement actions. Professional tissue banking organizations have also issued guidelines that provide recommendations for implementing efficacious policies and procedures for the acquisition, processing, storage, and distribution of tissues.

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Jung, Kyu Won. "Legal Issues in Tissue Bank." Journal of the Korean Medical Association 44, no. 11 (2001): 1151. http://dx.doi.org/10.5124/jkma.2001.44.11.1151.

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Allgayer, Heike, Christian Manegold, and Rainer Grobholz. "Establishing a Tumor Tissue Bank." American Journal of Cancer 5, no. 2 (2006): 93–98. http://dx.doi.org/10.2165/00024669-200605020-00003.

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Dissertations / Theses on the topic "Tissue Bank"

Lipworth, Wendy Louise. "Reconfiguring tissue banking consent through enrichment of a restricted debate." University of Sydney. History and Philosophy of Science, 2005. http://hdl.handle.net/2123/683.

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Tissue banks are thought to be an essential resource for medical research in the post-genomic age. Collections of tissue, usually removed in the course of diagnostic or therapeutic procedures, enable laboratory-based epidemiological studies to be carried out, linking abnormalities in the tissue to disease aetiology, prognosis and treatment responsiveness. There are, however, a number of technical, regulatory and ethical concerns that challenge those wishing to engage in tissue banking research. It is becoming increasingly apparent that tissue banking research is not without risk of harms, even though there is no direct physical risk to donors. This is because, in order to be most useful, banked specimens need to be linked to personal information about tissue donors and this poses the risk of inadvertent disclosure of personal─ particularly genetic─ information to those who might exploit such information (eg. insurance companies and employers). Furthermore, the long-term storage of specimens, and the impossibility of predicting all potential types of research programs for which they might be useful, raises the possibility that future projects will be carried out that are unacceptable to some (past) tissue donors. The ethical principles of autonomy and respect for persons demand that research subjects be informed of such risks and of the nature of the research, and that they participate willingly. On the other hand, there is a desire for science to progress unhindered by stringent consent requirements. For these reasons, a debate has emerged in the academic (bioethical and biomedical) literature and in the legal (law reform) sphere over what would constitute adequate consent. Despite an extensive discourse, it is still unclear whether it is permissible to carry out research on archival tissue that was originally taken for diagnostic purposes and whether project-specific (as opposed to open-ended) consent is required for research on tissue collected today. This lack of clarity is of concern to researchers, ethics committees and research subjects, all of whom recognise the importance of tissue banking research, yet fear that current consent procedures may be ethically or legally inadequate. Thus it is important that the consent dilemma be resolved as quickly and definitively as possible. Ongoing controversy and regulatory ambiguity are appropriate when morally contentious issues are at stake, and their existence does not, on its own, signal any flaws in the discourse process. There are, however, two reasons to suspect that the current �consent to tissue banking� debate, as portrayed in the academic literature and law reform documentation, is problematic. Firstly, the debate appears to be mired in an intractable conflict between those who want to maximise personal autonomy through stringent consent requirements, and those who want the scientific endeavour to progress in a manner that is unconstrained by what are viewed as arduous consent procedures. Secondly, the possible practical options (consent models) being generated by the debate are all limited because they are underpinned by a restricted notion of consent as an individualistic, legalistic and static activity, without consideration of any alternative conceptualisations of consent. Through a thematic analysis of the current �consent to tissue banking� debate in the academic and law reform literature (Section 3), this thesis shows that debate is essentially occurring between those who see individual autonomy (and stringent consent) as being of primary importance, and those who see unimpeded, market-driven scientific progress as the more important social good, which should not be impeded by unnecessarily stringent consent. Thematic analysis also confirms the existence of the two problems described above, and a failure of those engaged in the debate to reflect on, and challenge, the value-level assumptions underpinning their arguments and those of their opponents. It is argued that this lack of reflection accounts for the two problems: � Firstly, it precludes recognition of the cause of─ and, therefore, ways of resolving─ the intractable conflict at the centre of the debate. Value-level reflection shows that this is a result of the logical and moral conflict within western liberalism, between two modernist goods: individual freedom and scientific progress. � Secondly, it precludes the generation of varied conceptions of consent. Value-level reflection shows that the current range of consent models is restricted to procedures which are individualistic, abstract, static and legalistic, since they are underpinned by western liberal notions of autonomy and scientific progress. This recognition paves the way to consideration of alternative notions of autonomy, scientific progress and, therefore, consent, such as those derived from communitarian and feminist systems of values. A conceptually enriched model of tissue banking consent is then developed (Section 4). This model incorporates dominant (liberal) conceptions of autonomy and scientific progress as well as alternative notions of autonomy and scientific progress espoused by communitarian and feminist systems of values. It is argued that this conceptually-enriched model provides a practical solution to the two problems associated with the standard �consent to tissue banking� debate. In relation to the philosophically intractable conflict─ or what is termed the �modernist dilemma�─ between those privileging autonomy and those privileging scientific progress, it shows how the two apparently conflicting �modernist� goods can both be accommodated at a practical level, thus making the �consent to tissue banking� debate more tractable and fruitful. In relation to the restricted range of consent models being generated by the current debate, it provides new insights into the ways in which consent might be obtained such that a broader range of community values can be accommodated. More specifically, it stimulates the construction of a model that 1) involves communities, as opposed to merely individuals, in all stages of the scientific process; 2) is flexible and able to adapt consent procedures to specific contexts, rather than predefining procedures in abstract terms; and 3) is transactional and relational rather than static and legalistic. This outcome has interesting philosophical as well as practical implications. It shows that despite apparently unresolved, and possibly irresolvable, normative-level conflicts between the two modernist elements of western liberalism (autonomy and scientific progress), and between liberal, feminist and communitarian systems of values, a multi-perspectival, inclusive, model-building approach provides a practical solution that circumvents these normative-level conflicts.

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Murtomaa-Hautala, M. (Mari). "Species-specific effects of dioxin exposure on xenobiotic metabolism and hard tissue in voles." Doctoral thesis, Oulun yliopisto, 2012. http://urn.fi/urn:isbn:9789514297830.

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Abstract The evaluation of the effects and levels of contaminants in wildlife is an essential part of assessing risks for chemical exposure in the environment. Although the circumstances are not as controlled as in laboratory, wildlife studies offer the concept of environmental exposure in its entirety, with all the natural variation. In the present study, two wild vole species, bank vole (Myodes glareolus) and field vole (Microtus agrestis), were used in assessing environmental levels of dioxins. The effects of dioxin exposure on tooth and bone development were studied in order to determine whether they could be used as biomarkers for environmental exposure. Xenobiotic metabolism activity after dioxin exposure – both natural and experimental – was studied by quantifying selected cytochrome P-450 (CYP) enzymes. The results confirmed the fact that dioxins are ubiquitous in the environment, also in areas far from contaminant sources and human activity. The development of the third molar in bank vole was found to be a sensitive biomarker for dioxin exposure. The two vole species under study do not respond similarly to environmental concentrations of dioxins; there were significant differences in body burdens and activity levels of xenobiotic metabolizing enzymes
Tiivistelmä Haitallisten kemikaalien tason ja vaikutusten arviointi ympäristössä on olennainen osa kemikaalien riskin arviointia. Vaikka laboratoriossa olosuhteita kontrolloidaan ja tutkimukseen vaikuttava variaatio on paremmin hallittavissa, luonnonvaraisten lajien tutkiminen luo kokonaisvaltaisen ja todenmukaisen kuvan ympäristön kemikaalialtistuksesta kaikkine todellisine vaihteluineen. Tässä väitöskirjassa tarkastellaan kahden luonnonvaraisen pikkunisäkkään, metsämyyrän (Myodes glareolus) ja peltomyyrän (Microtus agrestis), käyttöä ympäristön kemikaalitason arvioinnissa. Pääpaino on dioksiinien kaltaisissa yhdisteissä. Työssä tutkitaan yhdisteiden kertymistä myyriin kahdessa ympäristössä: voimakkaasti dioksiineilla saastuneella maa-alueella sekä kaukana ihmistoiminnasta sijaitsevassa erämaassa. Herkiksi tiedettyjä vasteita – hampaiden ja luiden kehitystä – käytetään dioksiinialtistuksen indikaattoreina. Vierasainemetaboliasta vastaavien entsyymien (sytokromi P450 eli CYP) aktiivisuutta kartoitetaan molemmilla myyrälajeilla, jotta saadaan tietoa entsyymien indusoinnista luonnonvaraisilla myyrillä yleensä ja selvitetään havaittuja lajien välisiä eroja dioksiinivasteissa. Tulokset vahvistavat, että dioksiinit ovat laajalle levinneitä yhdisteitä, joita löytyy paitsi läheltä päästölähdettä myös kaukana ihmistoiminnasta olevilta alueilta. Metsämyyrällä kolmannen poskihampaan kehitys osoittautuu herkäksi dioksiinialtistuksen biomarkkeriksi. Samasta elinympäristöstä huolimatta tutkituista myyrälajeista mitatut dioksiinipitoisuudet eroavat huomattavasti toisistaan, samoin kuin vierasainemetaboliasta vastaavien entsyymien aktiivisuus ja niiden induktio TCDD-altistuksen jälkeen

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Triglia, Concetta. "Interpretive Phenomenological Analysis: Exploring the Experiences of Eye Bank Coordinators When Approaching Families of Decedents for Eye Donation." Diss., NSUWorks, 2018. https://nsuworks.nova.edu/hpd_hs_stuetd/9.

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This dissertation was used to addresses a group of individuals who work as eye bank coordinators. These individuals call families and approach them for eye donations from a loved one who has just passed away. An interpretative phenomenological analysis (IPA) was used to explain the lived experience of eye bank coordinators who call families for consent of eye tissue. The focus was to understand the dedication of the coordinators to giving the gift of sight and exploring the positive and negative experiences of eye bank coordinators. IPA is used for a keen understanding of eye bank coordinators, and the investigator gained insight as to why their role and well-being is important to eye banks by conducting and analyzing the interviews through the lived experiences of eye bank coordinators. The theoretical underpinnings of this research were based on the theory of planned behavior and self-perception theory. Four participants were interviewed as to their positive and negative experiences in their daily work. The research questions were What are the positive and negative experiences of eye bank coordinators when requesting permission for eye donations from bereaved families (RQ1)? and How do the positive and negative lived experience of eye bank coordinators influence their adjustment of strategies when requesting permission for eye donations from bereaved families (RQ2)? Encountering positive and enthusiastic family donors, needing to understand the situation or grief of family members, encountering closed-minded family members, and limited negative encounters experienced were the main themes that addressed RQ1. The main themes that addressed RQ2 were having the energy and motivation to seek for more donors, ensuring the right information was conveyed to the families, feeling more relaxed and comfortable, continuing to explain and ensure the correct information was conveyed, coaching and collecting oneself back, knowing how to read the actions and reactions of families, and learning from experiences and becoming more cautious.

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Santin, Stéfany Plumeri. "Avaliação morfológica e biomecânica dos efeitos da radiação gama em osso humano liofilizado ou congelado." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/85/85131/tde-04022014-153012/.

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Diversos pacientes são beneficiados com ossos armazenados em Bancos de Tecidos e utilizados em cirurgias reconstrutivas ortopédicas e em implantodologia como aloenxertos. No entanto, há uma intensa preocupação em garantir segurança na esterilidade do aloenxerto para proporcionar eficácia no transplante. Para minimizar possíveis contaminações utiliza-se a radiação ionizante como forma de esterilização final, desde que esta seja feita de maneira controlada, evitando possíveis modificações na matriz óssea. No presente trabalho, utilizamos as técnicas de colorimetria para avaliar modificações estéticas, Tomografia por Coerência Óptica, Tomografia por Coerência Óptica sensível à polarização, espectroscopia Raman e ensaios mecânicos de compressão para identificar as possíveis alterações na matriz óssea, ocasionadas pela forma de preservação, assim como, pelas diferentes doses de irradiação. Foram obtidas 8 amostras de fíbulas de 4 doadores, fracionadas de maneira a obter 48 amostras liofilizadas e 48 amostras congeladas. As amostras foram irradiadas com as doses de 15, 25 e 50 kGy comparando os resultados com o controle não irradiado. Observamos uma diminuição na intensidade das cores iniciais, mais relacionada com o processamento e preservação das amostras, e para as amostras irradiadas somente foi observado um aumento da coloração amarelada na dose de 50 kGy. A forma de preservação por liofilização ocasionou maiores modificações na estrutura terciária do colágeno dos ossos irradiados nas diferentes doses, principalmente nas doses acima de 25 kGy, porém estas modificações não foram suficientes para alterar a organização das fibras de colágeno. Quanto à resistência mecânica, verificou-se que as amostras liofilizadas foram menos resistentes que as congeladas e nas doses de 15 kGy e 25 kGy em ambas as formas de preservação ocorreu uma tendência a diminuir a resistência mecânica em relação ao controle.
Several patients are benefited with bones stored in Tissue Banks and used in orthopedic reconstructive surgery and implantodology as allografts. However, there is a strong concern to ensure safety in sterile allograft transplantation in order to provide efficacy. To minimize a probable contamination, ionizing radiation is used as a form of final sterilization, since the procedure is done in a controlled manner, avoiding possible changes in the bone matrix. In this dissertation, the techniques of colorimetry were used to evaluate aesthetic modifications; Optical Coherence Tomography, Optical Coherence Tomography sensitive to polarization, Raman spectroscopy and mechanical compression was carried out to identify possible changes in the bone matrix, caused by the preservation method, as well as the different irradiation doses. Eight fibulae from four donors were fractionated and from that forty-eight lyophilized samples and forty-eight frozen samples were obtained. The samples were irradiated with doses of 15, 25 and 50 kGy and the results were compared with the non-irradiated control. A decrease in the intensity of the initial colors was noticed and it was more related to the processing and preservation of the samples; for the irradiated samples, only an increase in the yellowness was observed, in the 50 kGy doses. The lyophilization preservation method caused major changes in the tertiary structure of the bone collagen irradiated at different doses, particularly at doses above 25 kGy, but these changes were not enough to change the organization of collagen fibers. Regarding the mechanical strength, were detected that lyophilized samples were less resistant than those which were frozen. With doses of 25 kGy and 15 kGy, in both forms of preservation, the mechanical strength tended to decrease, compared to the control. Therefore, it was observed that the aesthetic and structural changes caused by the different irradiation doses depend on the processing used in the Tissue Banks, besides the preservation method selected.

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Funari, Ana Paula. "Avaliação morfológica e biomecânica de tecido tendinoso humano esterilizado por radiação ionizante." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/85/85131/tde-23042018-093927/.

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O crescente aumento do interesse no desenvolvimento em técnicas cirúrgicas menos invasivas, como nas reconstruções tendíneas e ligamentares, tem levado ao aumento das pesquisas referentes ao uso de aloenxertos esterilizados por radiação ionizante. O processamento por radiação ionizante é um método seguro e não deixa resíduos, sendo utilizado como esterilização final. O presente estudo teve como proposta avaliar os efeitos da aplicação de radiação ionizante, produzida por fonte de 60Co, em amostras de tendões humanos pré processados de doadores multiorgãos obtidas por meio de colaboração com Bancos de Tecidos. O pré-processamento das amostras deu-se por métodos químicos e preservação por congelamento em -80 °C. As doses aplicadas no processamento por radiação foram de 12,5 kGy, 15,0 kGy e 25,0 kGy, cada uma com seu respectivo controle não irradiado. As amostras foram avaliadas por meio de testes histológicos, ópticos e biomecânicos, com o objetivo de analisar possíveis modificações morfológicas e estruturais. Os resultados apresentados demonstraram que o processamento por ultrassom e peróxido de hidrogênio causaram alterações na morfologia dos tecidos, o que ocasionou danos à sua estrutura, inviabilizando as amostras. Nas amostras processadas por álcool e antibiótico não foram observados danos na rede de colágeno pela aplicação da radiação. Os resultados dos testes biomecânicos apresentaram diferenças significativas entre os métodos aplicados. As amostras processadas com álcool e antibiótico apresentaram perda pouco significativa no módulo de elasticidade, comparadas às amostras processadas por ultrassom e peróxido de hidrogênio que mantiveram a propriedade viscoelástica. Contudo na dose de 12,5 kGy foi observado um aumento no módulo elástico e na viscoelasticidade. Com base nas análises, podemos concluir que o método de processamento com álcool, antibiótico e irradiação demonstrou menor dano, tanto na biomecânica quanto na esterilização, sendo que as amostras irradiadas a 15,0 e 25,0 kGy apresentaram características semelhantes ao controle não irradiado.
The increasing interest of development in less invasive surgical techniques, such as reconstructions of ligament tendon, has led to the increase of the research concerning the use of Allografts sterilized by ionizing radiation. Processing by ionizing radiation is a safe method and leaves no residues, being used as final sterilization. The present study was to evaluate the effects of proposed application of ionizing radiation, produced by 60Co source in human tendon pre-samples processed multiorgans donors obtained through collaboration with tissue banks. The pre-processing of samples given by chemical methods and preserved by freezing at -80 °C. The doses applied in radiation processing were 12.5, 15.0 and 25.0 kGy, each with your corresponding non-irradiated control. The samples were evaluated by means of histological and biomechanical testing, with the purpose of analyzing possible structural and morphological changes. The results showed that the ultrasound processing and hydrogen peroxide caused changes in the morphology of the tissues, which caused damage to the structure, making your samples. In the samples processed by alcohol and antibiotics were not observed damage on the network of collagen by the application of radiation. The results of biomechanical tests showed significant differences between the methods used. The samples processed with alcohol and antibiotics showed negligible loss in modulus of elasticity compared with the samples processed by ultrasound and hydrogen peroxide which kept the viscoelastic property, however in 12.5 kGy dose was observed an increase in elastic modulus and viscoelasticity. Based on the analysis we can conclude that the method of processing with alcohol, antibiotics and irradiation showed less damage, both in biomechanics and sterilization, in the samples irradiated with 15.0 and 25.0 kGy, showing results similar to the non-irradiated control.

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Lipworth, Wendy. "Reconfiguring tissue banking consent through enrichment of a restricted debate." Connect to full text, 2005. http://hdl.handle.net/2123/683.

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Thesis (M. Sc.)--University of Sydney, 2005.
Title from title screen (viewed 21 May 2008). Submitted in fulfilment of the requirements for the degree of Master of Science to the Unit for the History and Philosophy of Science and Centre for Values, Ethics and Law in Medicine. Includes bibliographical references. Also available in print form.

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Oliveira, Márcia Maria Benevenuto de. "A representação social de mulheres doadoras de leite humano." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/83/83131/tde-12052017-114529/.

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O leite humano pasteurizado vem sendo apresentado como a alternativa mais eficaz para alimentar prematuros e também recém-nascidos cujas mães estejam com alguma dificuldade para amamentar. Para suprir essa demanda, aumentou significativamente a implantação de bancos de leite humano no Brasil e no mundo. O objetivo desta pesquisa foi conhecer as representações sociais sobre a doação de leite entre mulheres colaboradoras do banco de leite humano em um hospital universitário público. Os referenciais teórico e metodológico utilizados foram, respectivamente, a Teoria das Representações Sociais e a Análise de Conteúdo. Para os dados quantitativos, foi utilizada a análise estatística descritiva. Foram entrevistadas 30 mulheres cadastradas como doadoras no Banco de Leite Humano do Hospital Universitário de Londrina, no Paraná. A idade variou de 18 a 44 anos, a maioria teve seus filhos por cesariana, 96,7% estavam com o companheiro, 86,7% possuíam curso superior completo ou pós-graduação, 76,7% exerciam trabalho remunerado fora de casa, o maior volume de leite doado foi 88 litros, o tempo médio de doação foi 155 dias e o tempo médio de aleitamento materno foi de 371 dias. Das falas dessas mulheres emergiram quatro temas com suas respectivas categorias: A experiência de amamentar; O banco de leite humano: lugar de acolhimento e aprendizagem; A doação dá trabalho e exige compromisso e Ser doadora é compartilhar o que tem e ajudar a quem precisa. A gênese para uma mulher se tornar doadora é estar amamentando seu filho e esse processo, proveniente da sua vivência familiar, apresenta-se como tendo um lado bom e outro que exige desafios, mas ela percebe que seu leite é único, que sua produção é mais do que suficiente para seu filho, levando essa mulher a procurar o banco de leite para compartilhar esse alimento com outras crianças. O banco de leite se torna para ela um local de acolhimento, apoio e aprendizado e ela se torna divulgadora desse serviço. Também passa a conhecer as histórias de doação e constata que doar seu leite dá trabalho, mas o compromisso assumido supera tal dificuldade; o apoio da família é essencial e ela descobre a sua maneira de ordenhar esse leite. Expressa que sente muito orgulho por ser uma doadora e, ao se perceber nessa condição, as suas representações sociais vinculam-se à construção social da solidariedade e de um sentimento mais profundo do significado da maternidade, que lhes propicia o sentimento de ampliar, para além de seu filho, o sentir ser mãe de muitos, em que compartilhar o que tem e ajudar a quem precisa resulta na sensação de ver mulptiplicado o papel materno e conhcer que doar vale a pena. Os elementos aqui identificados oferecem subsídios importantes para a condução de campanhas e projetos de melhoria de adesão de doadoras nos trabalhos dos Bancos de Leite Humano.
Pasteurized human milk has presented itself as the most effective alternative to feed preterm babies as well as newborns whose mothers are having some difficulty to breastfeed. In order to supply this demand, the number of human milk banks has significantly increased worldwide and in Brazil as well. The aim of this study was to acknowledge the social representation of human milk donation among women who donated to a human milk bank from a public hospital. The Social Representation Theory and Content Analysis were used as theoretical and methodological approaches, respectively. Quantitative data was assessed using descriptive statistical analysis. Thirty women were interviewed, all were donors at the Human Milk Bank from Londrina´s University Hospital, in Paraná State. Their age ranged from 18 to 44 years old, most had caesarean-sections, 96.7% had a companion; 86.7% had higher education or were postgraduates; 76.7% had a paid job; the biggest amount of donated milk was 88 liters; average donation period was 155 days; and average breastfeeding period was 371 days. Four themes and categories emerged from the women´s speeches: The breastfeeding experience; The human milk bank: a welcoming and learning place; Donating is hard-working and demands commitment; and Being a donor is sharing what I have and helping with others need. What motivates a woman to become a human milk donor involves the experience of breastfeeding her baby, which presents itself as a positive attitude, however posing some challenges. She realizes that her milk is unique, that she produces more than her baby can take, so she goes to the milk bank to share this nourishment with other children. The human milk bank becomes a welcoming, supportive and learning place for her, who spreads the word about this service/facility. These women also become aware of donation stories and comprehends that donating their milk is hardworking, but the commitment overcomes the difficulties; family support is essential; and they find out their own way to express the milk. These donating women reveal that they are proud to be a donor, and by acknowledging themselves as such, their social representations link to the social construction of solidarity and a deeper feeling of what maternity means. This allows them to amplify the motherhood feeling, beyond their own child, as they feel they are the mother of many. Also, sharing what they have and helping those in need results in the visualization of the multiplication of the mother´s role and understanding that donating milk is worthwhile. The elements identified in this study offer important ground to implement campaigns and projects to improve compliance in Human Milk Bank donations.

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Junior, Antonio Carlos Martinho. "Estudo dos efeitos da radiação ionizante em cartilagem costal humana por meio de Termogravimetria e Tomografia por Coerência Óptica." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/85/85131/tde-05112012-091524/.

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Bancos de Tecidos de diversas regiões do mundo têm estocado cartilagens humanas obtidas de doadores post mortem para uso em diversos tipos de cirurgias reconstrutivas. Para garantir que tais tecidos não estejam contaminados, estes têm sido esterilizados com radiação ionizante. Entretanto, altas doses de radiação gama podem causar efeitos indesejáveis nos tecidos. No presente trabalho, avaliamos a viabilidade de utilizar duas técnicas, Tomografia por Coerência Óptica (OCT) e Termogravimetria (TGA), para identificar possíveis modificações estruturais causadas na cartilagem costal humana em decorrência dos métodos de preservação e doses de radiação ionizante utilizadas. As cartilagens obtidas de doadores cadavéricos foram congeladas a -70 ºC ou preservadas em glicerol. A seguir, as amostras foram irradiadas por fontes de 60Co com doses de 15, 25 e 50 kGy. Nos resultados de TGA verificamos que as cartilagens preservadas em glicerol e irradiadas com diferentes doses de radiação não apresentaram diferenças estatisticamente significantes quando comparadas ao grupo controle, no que tange a taxa de desidratação do tecido, sendo que o mesmo não ocorre com cartilagens congeladas a -70 ºC e irradiadas com doses de 15 kGy. Em relação ao uso da técnica de OCT, por meio do cálculo do coeficiente de atenuação óptica total, verificamos que doses de 15 kGy promovem a criação de ligações cruzadas entre as fibrilas de colágeno, corroborando os resultados de TGA. Ainda, os valores do coeficiente de atenuação óptica total são diretamente proporcionais à tensão de ruptura das cartilagens, o que nos possibilitará, em um futuro próximo, predizer a qualidade de um enxerto sem a necessidade de perda de material biológico, visto ser o OCT um método não destrutivo. Por meio das imagens de PS-OCT podemos verificar que as doses de radiação utilizadas para esterilizar as amostras não provocam danos à rede de colágeno a ponto de que sua birrefringência seja perdida. Assim, o TGA e OCT são técnicas que podem ser utilizadas por bancos de tecidos de forma a verificar a qualidade dos tecidos antes de serem transplantados em pacientes.
Tissue Banks around the world have stored human cartilages obtained from post mortem donors for use in several kinds of reconstructive surgeries. To ensure that such tissues are not contaminated, they have been sterilized with ionizing radiation. However, high doses of gamma radiation may cause undesirable changes in the tissues. In this work, we evaluated the possibility of use Optical Coherence Tomography (OCT) and Thermogravimetric Analysis (TGA) to identify possible structural modifications caused by both preservation methods of cartilage and gamma irradiation doses. Cartilages were obtained from cadaveric donors and were frozen at -70 ºC or preserved in glycerol. Irradiation was performed by 60Co source with doses of 15, 25 and 50 kGy. Our TGA results showed that glycerolized cartilages irradiated with different doses of radiation does not presented statistical differences when compared to the control group for the dehydration rate. However, the same was not observed for deep-fronzen cartilages irradiated with 15 kGy. The results of OCT associated to total optical attenuation coefficient showed that doses of 15 kGy promote cross-link between collagen fibrils, corroborating the results obtained from TGA. Moreover, total optical attenuation coefficient values are proportionals to stress at break of cartilages, what will be very useful in a near future to predict the quality of the allografts, without unnecessary loss of biological tissue, once OCT is a nondestructive technique. By PS-OCT images, we found that high doses of ionizing radiation does not promote sufficient impairments to promote complete loss of tissue birefringence. Thus, TGA and OCT are techniques that can be used for tissue banks to verify tissue quality before its transplant.

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Almeida, Hirlana Gomes. "Transplante de córnea no Brasil: progresso e dificuldades em 16 anos." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/5/5149/tde-28092018-104410/.

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Introdução: As doenças da córnea são responsáveis por cerca de 5% da cegueira reversível no mundo e o transplante de córnea (TC) é importante para o tratamento dessas enfermidades. A partir de fontes de dados oficiais e públicas, foram analisados o progresso e as dificuldades relacionados ao TC no Brasil nos últimos 16 anos, bem como desigualdades regionais, gastos do Sistema Único de Saúde (SUS) e indicadores de qualidade dos bancos de tecido ocular (BTOs). Métodos: Estudo retrospectivo e analítico com dados sobre TCs e BTOs no Brasil, no período de janeiro de 2001 a dezembro de 2016, divulgados pelo Sistema Nacional de Transplantes (SNT), pela Associação Brasileira de Transplante de Órgãos (ABTO) e pela Agência Nacional de Vigilância Sanitária (ANVISA). Para verificação de existência de tendência, comparação de médias entre as regiões e verificação da diferença de médias, foram utilizados o teste de Cochran-Armitage, a Análise de Variância e as comparações múltiplas de Duncan, respectivamente. Em todos os testes foi utilizado um nível de significância de 5%. Resultados: No Brasil, houve aumento: de 2,4 vezes no número de TCs (de 6.193 - 35,2 pmp para 14.641 - 71,0 pmp - p < 0,001); de 50,7% na eficácia do atendimento à demanda populacional por TCs (de 35,3% para 53,2% - p < 0,001); de 27,8% no número de globos e córneas in situ doados (de 24.608 - 127,1 pmp para 31.450 - 152,6 pmp - p < 0,001); de 31,7% nas córneas preservadas (de 21.012 para 27.674); de 2,4 vezes no gasto financeiro total com TCs (de R$ 9.179.688 para R$ 22.060.973); e de 2,2 vezes no gasto unitário com TC (de R$ 716 para R$ 1.603). A fila de espera para TC reduziu em 45,4% (de 23.549 - 123,0 pmp para 12.865 - 62,4 pmp - p < 0,001). As duas principais causas para a não doação foram as contraindicações médicas (média de 42,5%) e a recusa familiar (média de 36,6%). As principais causas de descarte de córneas foram a sorologia positiva para hepatite B (média de 33%), validade tecidual (média de 30,9%) e qualidade imprópria do tecido (16,8%). A Eficácia na Preservação de Córnea (EPC), o Coeficiente de Descarte de Córnea (CDC) e a Eficácia no Fornecimento de Córnea para Transplante (ECT) foram em média 88%, 37% e 63% ao longo dos anos, respectivamente. Os melhores índices foram apresentados nas regiões Sul, Centro-Oeste e Sudeste e os piores no Norte e Nordeste. Conclusão: No Brasil, o pequeno número de doações e a grande taxa de descarte de córneas são as principais dificuldades ao adequado atendimento à demanda populacional por TCs. Contudo, o país aumentou a capacidade de transplantar córneas e reduziu as filas de espera em 16 anos
Introduction: Corneal diseases account for about 5% of reversible blindness in the world and Corneal Transplantation (CT) is important for the treatment of these diseases. From official and public data sources, the progress and difficulties related to CT in Brazil in the last 16 years were analyzed, as well as regional inequalities, expenses for the Unified Health System (SUS) and quality indicators of ocular tissue banks (OTBs). Methods: A retrospective and analytical study with data on CT and OTB in Brazil, from January 2001 to December 2016, published by the National Transplantation System (SNT), the Brazilian Organ Transplantation Association (ABTO) and the National Surveillance Agency Sanitary (ANVISA). The Cochran-Armitage test, the Analysis of Variance and the Duncan\'s multiple comparisons were used to verify the existence of trend, comparison of means between regions and verification of the mean difference, respectively. A significance level of 5% was used in all tests. Results: In Brazil, there was an increase: of 2.4 times in the number of CTs (from 6,193 - 35.2 pmp to 14,641 - 71.0 pmp - p < 0.001); of 50.7% in the efficacy of meeting the population demand for CTs (from 35.3% to 53.2% - p < 0.001); of 27.8% in the number of donated globes and corneas in situ (from 24,608 - 127.1 pmp to 31,450 - 152.6 pmp - p < 0.001); of 31.7% in preserved corneas (from 21,012 to 27,674); of 2.4 times in the total finance expense with CTs (from R$ 9,179,688 to R$ 22,060,973); and 2.2 times the unit expense with CT (from R$ 716 to R$ 1,603). The waiting list for CT decreased by 45.4% (from 23,549 - 123.0 pmp to 12,865 - 62.4 pmp - p < 0.001). The two main causes for non-donation were medical contraindications (mean of 42.5%) and family refusal (mean of 36.6%). The main causes of corneal discard were positive serology for hepatitis B (mean of 33%), tissue validity (mean of 30.9%) and inadequate tissue quality (16.8%). Efficacy in Corneal Preservation (EPC), Corneal Discarding Coefficient (CDC) and Efficacy Supply of Corneas for Transplantation (ECT) averaged 88%, 37%, and 63% over the years, respectively. The best indexes were presented in the South, Midwest and Southeast regions and the worst in the North and Northeast. Conclusion: In Brazil, the small number of donations and the high rate of discard of corneas are the main difficulties to the adequate attendance to the population demand by CTs. However, the country increased the ability to transplant corneas and reduced waiting lists in 16 years

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Viana, Cristiano Ribeiro. "Avaliação do impacto da implantação do controle de qualidade em um banco de amostras teciduais criopreservadas." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/5/5144/tde-28052013-105525/.

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Bancos de tumores foram criados para organizar a coleta, arm azenamento e distribuição de amostras biológicas de pacientes oncológicos, favorecendo seu uso nas pesquis as sobre o cân cer. Amostras ade quadas devem ter RNA, DNA e proteínas de boa qualidade. RNA de boa qualidade deve estar íntegro e puro e DNA deve ter boa c oncentração e pur eza. Basea do em norm as in ternacionais, f oi elaborado e implantado um abrangente sistema de controle de qualidade no banco de tumores do Hospital de Câncer de Barretos, que para fins de estudo foi dividido em banco pré-controle de qu alidade (den ominado b anco pré) e em ban co pós- controle de qualidade (denominado banco pós). Objetivando comparar a qualidade das amostras n os dois bancos, atra vés d a extração d e R NA total e d e DNA (utilizando-se homogeneizador de tecidos e Kits), selecionou-se de forma aleatória 200 a mostras tumorais, distribuídas ig ualitariamente entre mama, co lorreto, estômago, pulmão e tireóide, sendo 100 do banco pré e 100 do banco pós. Para se avaliar a influência do tempo de isquemia fria (tempo entre a excisão do e spécime cirúrgico e o congelamento rápido da amostra armazenada) na qualidade do RNA total de amostras tumorais do banco pós, foram coletadas 200 amostras tumorais, distribuídas igualitariamente entre mama, co lorreto, estômago, pulmão e ti reóide, de 100 doadores diferentes, metade com o tempo de isquemia fria (TIF) de até 30 minutos e a o utra metade do mesmo espécime com TIF de 45 minutos. Extraiu-se RNA total dessas amostras (com maceração manual e Trizol) e comparou-se a sua qualidade, através do núm ero de i ntegridade do RNA (RIN), dentr o dos d ois intervalos de tempo e nas diferentes top ografias. Ao c omparar-se amostras com RIN acima de 7 (consideradas ideais para experimentos de microarray), do banco pré e do b anco pó s, for am enc ontrados 73 (73%) no p rimeiro e 87 (87%) no segundo (p=0,013). Ao comparar-se o intervalo de TIF de até 30 minutos com o de 45 minutos, encontrou-se respectivamente 63 (64,3%) e 3 6 (36%) amostras com RNA total intacto, 11 (11,2%) e 17 (17 %) com RNA tot al parcialmente degradado e 24 (24, 5%) e 47 (47%) com RNA t otal degradado (p<0,001). Amostras tireoidianas e colorretais f oram mais sensíveis ao a umento d o T IF (p=0,006 e p=0,03, respectivamente), e as de estômago e pulmão menos sensíveis (p=0,919 e p=0,384, resp ectivamente). Ao comparar-se a s 200 amostras dos dois ban cos, constatou-se que a grande maioria apresentava boa qualidade, porém o banco pós se destacou ao avaliar-se o número de amostras ideais para estudos de microarray, por provável interferência d o TIF, ainda não controlado no banco pr é. Constatou-se também que algumas amostras do banco pré, armazenadas há mais de ci nco anos em freezer a -80ºC, apresentaram excelente qualidade. O presente estudo também mostrou que o TIF é muito importante para a preservação da qualidade do RNA total, por isso, deve-se sempre respeitar o tempo máximo de 30 minutos. Ainda se observou que a de gradação do RNA é tecido dependente e qu e amostras processadas com homogeneizador de tecidos e extraídas com RNeas y Mini Kit apresentaram melhor q ualidade do RNA, qu e as macer adas manualmente e extraídas com Trizol
Tumor banks were created to or ganize the collection, storage and d istribution of biological samples of cancer pa tients, favoring it\'s use in cancer rese arches. Appropriate samples should have good quality of RNA, DNA and p roteins. RNA of good quality should be intact and pure and DNA should have good concentration and pu rity. Ba sed on international sta ndards, we elabo rated and imp lanted an comprehensive s ystem of qu ality control in the tu mor bank of Ba rretos Cancer Hospital, w hich was divided for st udy purposes i n pre bank quality control (denominated pre bank) and post bank qu ality control (denominated post bank). Aiming to compare the quality of the samples in two banks, through the extraction of total RNA and DNA (b y tissue homogenizer and Kits), we se lected 200 tumor samples in a random way, distributed equally among breast, colorectal, stomach, lung and thyroid, being 100 of the pre-bank and 100 of the post bank. To evaluate the influence o f cold ischem ia time (time b etween t he ex cision o f the su rgical specimen and the fast freezing of the stored sample) in the quality of total of RNA tumor sa mples of th e po st bank , we collected 2 00 t umor s amples, distrib uted equally among breast, colorectal, stom ach, lung and th yroid, fro m 100 different donors, half with the cold ischemia time (CIT) up to 30 minutes and the other ha lf of the sam e specimen with CIT exact ly 45 minutes. We ex tracted total RNA of these samples (with manual maceration and T rizol) and c ompared their qu ality, through the RNA integri ty number (RIN), ins ide tw o intervals of time a nd in different topographies. Comparing samples with RIN above 7 (considered ideals for microarray experiments), of the pre bank and of the post bank, we found 73 (73%) in the first and 87 (87%) in the second (p=0,013). Comparing the interval of CIT up to 30 m inutes with the ex actly 45 minutes, we found respectively 63 (64,3%) and 36 (36%) samples with total RNA intact, 11 (11,2%) and 17 (17%) with total RNA partially degraded and 24 (2 4,5%) and 47 (47%) wit h total RNA de graded (p<0,001). Thyroid and colorectal samples were more sensitive to the increase of CIT (p =0,006 and p=0,03, respectively), a nd s tomach and lun g samples less sensitive (p=0,919 and p=0,384, respectively). C omparing the 200 samples from the two b anks, we v erified that the great ma jority had good qu ality; however the post bank stood out the evaluating number of the id eal samples for m icroarray studies, for probable interference of CIT, still n o controlled in the pre bank. We also verified that some samples of the pre bank, stored more than 5 years in freezer at -80 ºC presented e xcellent qu ality. T he stu dy still sho wed that CIT is ver y important to preserve the quality of total RNA, for that, we sh ould always respect the maximum time of 30 minutes. We still observed that the degradation of RNA is tissue dependent and that samples processed with tissue homogenizer and extracted using RNeasy Mini Kit showed better quality of RNA that macerated manually and extracted with Trizol

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Books on the topic "Tissue Bank"

Porter, Barbara J. National Biomonitoring Specimen Bank, Alaska Marine Mammal Tissue Archival Project, and the National Marine Mammal Tissue Bank specimen inventory. Gaithersburg, MD: U.S. Dept. of Commerce, Technology Administration, National Institute of Standards and Technology, 1999.

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National Biomonitoring Specimen Bank (U.S.). National Biomonitoring Specimen Bank, Alaska Marine Mammal Tissue Archival Project, and the National Marine Mammal Tissue Bank specimen inventory. Gaithersburg, MD]: U.S. Dept. of Commerce, Technology Administration, National Institute of Standards and Technology, 1999.

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Sim, Sŏng-bo. Taedanwi chojik ŭnhaeng (regional tissue bank) sŏllip sibŏm saŏp chʻujin pangan yŏnʼgu =: A study to promote establishment of a new model of regional tissue bank. [Seoul]: Sikpʻum Ŭiyakpʻum Anjŏnchʻŏng, 2007.

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United States. Congress. Senate. Committee on Environment and Public Works. Great Lakes Fish and Wildlife Restoration Act of 1998: Report (to accompany S. 659). [Washington, D.C: U.S. G.P.O., 1998.

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United States. Congress. House. Committee on Merchant Marine and Fisheries. The Great Lakes Fish and Wildlife Tissue Bank Act: Report (to accompany H.R. 5350) (including cost estimate of the Congressional Budget Office). [Washington, D.C.?: U.S. G.P.O., 1992.

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Fisheries, United States Congress House Committee on Merchant Marine and. The Great Lakes Fish and Wildlife Tissue Bank Act: Report (to accompany H.R. 5350) (including cost estimate of the Congressional Budget Office). [Washington, D.C.?: U.S. G.P.O., 1992.

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Council, Medical Research. MRC brain bank review: Post mortem brain tissue in medical research : the MRC's role and guidelines for MRC-funded brain banks. London: Medical Research Council, 1995.

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Eisenbrey, A. Bradley. Hospital tissue management: A practitioner's handbook. Edited by Easthund D. Ted, American Association of Blood Banks, American Association of Tissue Banks, and Eye Bank Association of America. Bethesda, Md: AABB, 2008.

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Frizzo, Wendy L. Tissue management self-assessment tool: For transfusion services and hospitals. Bethesda, Md: AABB Press, 2008.

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Book chapters on the topic "Tissue Bank"

Mahyudin, Ferdiansyah, and Heri Suroto. "Tissue Bank and Tissue Engineering." In Advanced Structured Materials, 207–34. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-14845-8_9.

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Manyalich, Martí, Debbie Butler Newman, Jacinto Sánchez-Ibáñez, Aurora Navarro, Gloria Páez, and Aziz Nather. "Training of Tissue Bank Personnel." In Tissue and Cell Processing, 180–96. Oxford, UK: Blackwell Publishing Ltd., 2012. http://dx.doi.org/10.1002/9781118316467.ch10.

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Strong, W. Ronald. "The Tissue Bank, its Operation and Management." In Novartis Foundation Symposia, 220–33. Chichester, UK: John Wiley & Sons, Ltd., 2008. http://dx.doi.org/10.1002/9780470718889.ch17.

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Měřička, Pavel, Leo Klein, Jindřich Preis, and Eva EttlerovÁ. "The Role of a Tissue Bank in Disaster Planning." In The Management of Burns and Fire Disasters: Perspectives 2000, 75–83. Dordrecht: Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-009-0361-6_13.

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Zeugner, Silke, Thomas Mayr, Christian Zietz, Daniela E. Aust, and Gustavo B. Baretton. "RNA Quality in Fresh-Frozen Gastrointestinal Tumor Specimens—Experiences from the Tumor and Healthy Tissue Bank TU Dresden." In Pre-Analytics of Pathological Specimens in Oncology, 85–93. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-13957-9_9.

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Lee-Ong, Alembert, and Alfred Allen Buenafe. "Imaging-Enhancing System." In Mastering Endo-Laparoscopic and Thoracoscopic Surgery, 45–49. Singapore: Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-19-3755-2_8.

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AbstractVisualization is one of the fundamental pillars (including CO2 insufflation and instrumentation) critical to performing MIS. Initially evolved from direct view through the laparoscope to indirect view on the monitor projected from a camera system. Early advances were geared towards improving the image quality and reproduction of stereoscopic vision. Current advancements involve in part or in combination, the application of optical filters to manipulate specific light spectrums (narrow-band imaging) and the use of fluorescent dye (indocyanine green-fluorescent imaging) to see beyond what can be viewed with the naked eye, coupled with the advantage of real-time application. Narrow-band imaging is primarily used in gastrointestinal endoscopy to detect mucosal pathologies, while ICG aid in revealing specific structures beneath tissues and assess tissue perfusion; it is finding interest for application in various MIS procedures.

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Roux, Nicolas, Rachel Chase, Ines van den Houwe, Chih-Ping Chao, Xavier Perrier, Jean-Pierre Jacquemoud-Collet, Julie Sardos, and Mathieu Rouard. "Somaclonal variation in clonal crops: containing the bad, exploring the good." In Mutation breeding, genetic diversity and crop adaptation to climate change, 355–65. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781789249095.0037.

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Abstract Somaclonal variation describes random cellular changes in plants regenerated through tissue culture. It occurs in certain crops that undergo micropropagation and has been recorded in different explant sources, from leaves and shoots to meristems and embryos. In banana (Musa spp.), a clonal crop conserved in vitro, somaclonal variation has been observed after prolonged periods in tissue culture, resulting from an increase in subcultures performed on a given clone. According to scientific literature, variants, or off-types, often show characteristics such as abnormal growth and flower or fruit defects in frequencies ranging from 1% to 32%. This variation poses a problem for gene bank managers, whose mandate is to maintain the genetic integrity of their collections for research and breeding. In the case of the Bioversity International Musa Germplasm Transit Centre (ITC), stress during the in vitro process is minimized by various techniques and plants are regenerated after 10 years, making it a long and costly process. Identifying somaclonal variation at an early stage would be an ideal solution; however, this requires suitable molecular markers. Recent studies revealed that techniques such as direct DNA sequencing and single nucleotide polymorphisms (SNPs) are able to detect the underlying factors of somaclonal variation and are becoming more accessible. On the other hand, somaclonal variation can be beneficial as it allows the natural development of new varieties and supplies genetic stocks used for future genetic studies. Harnessing the diversity of somaclones is easier, faster and cheaper compared with other methods of crop improvement, although it is also less predictable. So far, variants of crops such as apple, strawberry, potato and banana have been successfully adopted into global markets. In this chapter, we will discuss how to minimize the adverse effects of somaclonal variation while maximizing its benefits for greater crop diversity, with a particular focus on banana.

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Poitout, D. G. "Bone Materials and Tissue Banks." In Biomechanics and Biomaterials in Orthopedics, 54–64. London: Springer London, 2004. http://dx.doi.org/10.1007/978-1-4471-3774-0_5.

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Poitout, Dominique G. "Bone Materials and Tissue Banks." In Biomechanics and Biomaterials in Orthopedics, 71–82. London: Springer London, 2016. http://dx.doi.org/10.1007/978-1-84882-664-9_6.

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Cahane, Michael, and Jeroen van Baare. "European Association of Tissue Banks." In Eye Banking, 131–35. Basel: KARGER, 2009. http://dx.doi.org/10.1159/000223847.

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Conference papers on the topic "Tissue Bank"

LaFramboise, William A., Sujal Shah, R. W. Hoy, D. Letbetter, P. Petrosko, R. Vennare, and Peter C. Johnson. "Creation of a virtual cutaneous tissue bank." In BiOS 2000 The International Symposium on Biomedical Optics, edited by Daniel L. Farkas and Robert C. Leif. SPIE, 2000. http://dx.doi.org/10.1117/12.384233.

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Morgan, A., J. Gath, M. MacKenzie, A. Matthews, H. Stobart, L. Turner, and M. Wilcox. "Abstract P1-10-01: Patient advocate involvement shapes UK’s first national breast cancer tissue bank - The breast cancer campaign tissue bank." In Abstracts: Thirty-Sixth Annual CTRC-AACR San Antonio Breast Cancer Symposium - Dec 10-14, 2013; San Antonio, TX. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/0008-5472.sabcs13-p1-10-01.

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Juhn, Eric, and John A. Springer. "A usability study of the Komen Virtual Tissue Bank." In 2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW). IEEE, 2012. http://dx.doi.org/10.1109/bibmw.2012.6470288.

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Jones, L., C. Chelala, I. Ellis, U. Ekbote, A. Green, A. Hanby, L. Jordan, C. Purdie, P. Quinlan, and V. Speirs. "P5-21-03: The Breast Cancer Campaign Tissue Bank." In Abstracts: Thirty-Fourth Annual CTRC‐AACR San Antonio Breast Cancer Symposium‐‐ Dec 6‐10, 2011; San Antonio, TX. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/0008-5472.sabcs11-p5-21-03.

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Kuang, Yuting, Lingling Guo, Yongsheng Zhang, Lingchuan Guo, Maomin Sun, and Shouli Wang. "Quality control for tumor tissue bank of gastrointestinal tract carcinoma." In International Conference on Medical Engineering and Bioinformatics. Southampton, UK: WIT Press, 2014. http://dx.doi.org/10.2495/meb140441.

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Kuang, Yuting, Lingling Guo, Yongsheng Zhang, Lingchuan Guo, Maomin Sun, and Shouli Wang. "Quality control for tumor tissue bank of gastrointestinal tract carcinoma." In International Conference on Modern Engineering Soultions for the Industry. Southampton, UK: WIT Press, 2014. http://dx.doi.org/10.2495/mesi140441.

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McCarty, Julia R., Guanlong Jiang, Mariah L. Johnson, Teresa Mahin, Nicholas Scherer, Jonathon Dunn, Anna Maria Storniolo, and Natascia Marino. "Abstract 5281: Komen Tissue Bank donors: Genetically determined ethnicity and race." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-5281.

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Figueroa, Jonine D., Laura Linville, Louise A. Brinton, Deesha Patel, Susan E. Clare, Daniel Visscher, Carrolyn Mies, et al. "Abstract 4465: Breast cancer risk factor associations with breast tissue morphometry: results from the Komen for the Cure® Tissue Bank." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-4465.

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Speirs, V., R. Good, A. Hanby, B. Matharoo-Ball, B. Thomson, I. Ellis, P. Quinlan, et al. "Abstract P4-19-02: Early experience of patient donation and researcher use of tissues donated to a national breast cancer tissue bank." In Abstracts: Thirty-Sixth Annual CTRC-AACR San Antonio Breast Cancer Symposium - Dec 10-14, 2013; San Antonio, TX. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/0008-5472.sabcs13-p4-19-02.

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Clare, S., J. Sun, J. Henry, T. Mathieson, P. Mitchum, S. Badve, C. Rufenbarger, C. Rufenbarger, and A. Storniolo. "The Susan G. Komen for the Cure® Tissue Bank at the IU Simon Cancer Center: The Source for Normal Breast Tissue and Biospecimens." In Abstracts: Thirty-Second Annual CTRC‐AACR San Antonio Breast Cancer Symposium‐‐ Dec 10‐13, 2009; San Antonio, TX. American Association for Cancer Research, 2009. http://dx.doi.org/10.1158/0008-5472.sabcs-09-3076.

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Reports on the topic "Tissue Bank"

Slamon, Dennis J. UCLA/USC Tumor Tissue Bank. Fort Belvoir, VA: Defense Technical Information Center, October 1998. http://dx.doi.org/10.21236/ada371370.

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Salmon, Dennis J. UCLA/USC Tumor Tissue Bank. Fort Belvoir, VA: Defense Technical Information Center, October 1996. http://dx.doi.org/10.21236/ada323764.

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Slamon, Dennis J. UCLA/USC Tumor Tissue Bank. Fort Belvoir, VA: Defense Technical Information Center, October 1995. http://dx.doi.org/10.21236/ada302658.

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Slamon, Dennis J. UCLA/USC Tumor Tissue Bank. Fort Belvoir, VA: Defense Technical Information Center, October 1997. http://dx.doi.org/10.21236/ada352349.

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Slamon, Dennis J. UCLA/USC Tumor Tissue Bank. Fort Belvoir, VA: Defense Technical Information Center, October 1999. http://dx.doi.org/10.21236/ada391187.

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Pugh, Rebecca S., Michael B. Ellisor, Amanda J. Moors, Barbara J. Porter, John R. Kucklick, Steven J. Christopher, W. Clay Davis, and Paul R. Becker. National marine mammal tissue bank 2007-2008. Gaithersburg, MD: National Institute of Standards and Technology, 2010. http://dx.doi.org/10.6028/nist.ir.7675.

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Pugh, Rebecca S., Michael B. Ellisor, Amanda J. Moors, Paul R. Becker, Barbara J. Porter, Elizabeth A. Mackey, Michele M. Schantz, Rabia Demiralp, and Stephen A. Wise. The national marine mammal tissue bank specimen inventory. Gaithersburg, MD: National Institute of Standards and Technology, 2006. http://dx.doi.org/10.6028/nist.ir.7372.

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Becker, Paul R., Barbara J. Porter, Elizabeth A. Mackey, Michele M. Schantz, Rabia Demiralp, and Stephen A. Wise. National Marine Mammal Tissue Bank and Quality Assurance Program:. Gaithersburg, MD: National Institute of Standards and Technology, 1999. http://dx.doi.org/10.6028/nist.ir.6279.

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Kandel, Rita A. A Cohert Study of the Relationship Between c-erbB-2 and Cyclin D1 Overexpression, p53 Mutation and/or Protein Accumulation, and Risk of Progression from Benign Breast Disease to Breast Cancer; and Creation of a Bank of Benign Breast Tissue. Fort Belvoir, VA: Defense Technical Information Center, October 2000. http://dx.doi.org/10.21236/ada394725.

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Ness, Jennifer M., Amanda J. Moors, and Rebecca S. Pugh. Risk assessment of brucellosis for tissues processed and archived at the marine environmental specimen bank. Gaithersburg, MD: National Institute of Standards and Technology, March 2017. http://dx.doi.org/10.6028/nist.sp.1211.

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