Relevant bibliographies by topics / Thymus Physiological effect

Academic literature on the topic 'Thymus Physiological effect'

Author: Grafiati
Published: 10 December 2022
Last updated: 29 January 2023

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Journal articles on the topic "Thymus Physiological effect"

1

Chesnokov, Alexander A., Elena S. Golovaneva, and Gennady V. Bryukhin. "EFFECT OF HIGH-INTENSITY LASER THERAPY ON MORPHOFUNCTIONAL CHARACTERISTIC OF THYMUS ON DIFFERENT TERMS OF EXPERIMENT." Journal of Volgograd State Medical University 19, no. 1 (March 31, 2022): 79–83. http://dx.doi.org/10.19163/1994-9480-2022-19-1-79-83.

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The purpose of the work was to study the effect of high-intensity laser exposure in the therapeutic mode on the morphofunctional state of rat thymus. Material and methods. The experiment was carried out on 54 rats, divided into 2 groups: control (intact animals) and experimental – a single exposure of laser radiation on the thymus region (970 nm, 1 W/cm2 IRE-Polus, Russia). Extraction from the experiment and material sampling were carry out after 1 hour, 1, 3, 7 day after exposure. Histological sections stained with hematoxylin-eosin were study using digital morphometry. Results. A single laser exposure on the thymus led to a change in the relative area of the functional zones of the thymus and their cell density, as well as an increase in the number of Gassal’s bodies in the thymic slices and an increase in the relative area of the vascular channel.
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MOSAVAT, Nima, Maryam YOUSEFIFARD, Pooran GOLKAR, and Rabia JAVED. "Influence of Ag nanoparticles on physiological and biochemical aspects of callus of Thymus species and Zataria multiflora Boiss." Acta agriculturae Slovenica 118, no. 3 (October 20, 2022): 1. http://dx.doi.org/10.14720/aas.2022.118.3.1873.

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<p class="042abstractstekst"><em>Thymus</em> species have found remarkable importance in food and medicine industries. The present study investigates the potential effect of Ag nanoparticle elicitors on proliferation of callus, and production of carvacrol and thymol in <em>Zataria multiflora</em> and three <em>Thymus </em>species. Firstly, callus was induced on Murashige and Skoog (MS) medium containing 2 mg l<sup>−1</sup> of 2, 4-dichlorophenoxy acetic acid (2,4-D) and 1 mg l<sup>−1</sup> of kinetin (Kin)). Secondly, the effects of two different concentrations of Ag nanoparticles (4 and 8 mg l<sup>-1</sup>) were studied on callus growth and its secondary metabolites production. Results elucidated that after elicitation by 8 mg l<sup>-1 </sup>ofAg NPs, significantly the highest callus growth rate (CGR) (0.02 mm day<sup>-1</sup>), callus fresh mass (CFM) (0.99 g), and carvacrol (0.68 mg l<sup>-1</sup>) and thymol (11.09 mg l<sup>-1</sup>) content was achieved. Comparing different <em>Thymus</em> species, notably the greatest<em> </em>carvacrol and thymol amount was obtained in <em>.kotschyanus</em> Boiss. &amp; Hohen. and<em> T</em><em>. Daenesis </em><em>Č</em><em>elak</em><em>.</em> at 8 mg l<sup>-1 </sup>concentration ofAg NPs. Hence, it is evident that the stimulation by NPs is dose-dependent. This study has potential to be commercially applied for the enhancement of pharmaceutical compounds in different species of <em>Thymus</em>.</p>
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Bistgani, Zohreh Emami, Masoud Hashemi, Michelle DaCosta, Lyle Craker, Filippo Maggi, and Mohammad Reza Morshedloo. "Effect of salinity stress on the physiological characteristics, phenolic compounds and antioxidant activity of Thymus vulgaris L. and Thymus daenensis Celak." Industrial Crops and Products 135 (September 2019): 311–20. http://dx.doi.org/10.1016/j.indcrop.2019.04.055.

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4

Rahawi, Ghadeer. "Effect of Thymus and Anis and Mixture on some Physiological and Productive Traits of Quail." Rafidain Journal of Science 27, no. 3 (September 1, 2018): 49–61. http://dx.doi.org/10.33899/rjs.2018.159377.

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Guo, Xiao-Kai, Yuan-Feng Liu, Yu Zhou, Xiu-Yuan Sun, Xiao-Ping Qian, Yu Zhang, and Jun Zhang. "The Expression of Netrin-1 in the Thymus and Its Effects on Thymocyte Adhesion and Migration." Clinical and Developmental Immunology 2013 (2013): 1–10. http://dx.doi.org/10.1155/2013/462152.

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Netrin-1, a known axon guidance molecule, being a secreted laminin-related molecule, has been suggested to be involved in multiple physiological and pathological conditions, such as organogenesis, angiogenesis, tumorigenesis, and inflammation-mediated tissue injury. However, its function in thymocyte development is still unknown. Here, we demonstrate that Netrin-1 is expressed in mouse thymus tissue and is primarily expressed in thymic stromal cells, and the expression of Netrin-1 in thymocytes can be induced by anti-CD3 antibody or IL-7 treatment. Importantly, Netrin-1 mediates the adhesion of thymocytes, and this effect is comparable to or greater than that of fibronectin. Furthermore, Netrin-1 specifically promotes the chemotaxis of CXCL12. These suggest that Netrin-1 may play an important role in thymocyte development.
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Meijer, MK, K. Kramer, R. Remie, BM Spruijt, LFM van Zutphen, and V. Baumans. "The effect of routine experimental procedures on physiological parameters in mice kept under different husbandry conditions." Animal Welfare 15, no. 1 (February 2006): 31–38. http://dx.doi.org/10.1017/s0962728600029912.

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AbstractLaboratory animals are frequently subjected to routine procedures, such as injections or the withdrawal of blood samples. Acute stress caused by such procedures is associated with physiological changes that can have a strong impact on experimental results. This study investigated the integrated effects of cage enrichment, social housing and handling on the acute stress response of animals subjected to routine experimental procedures. Female mice of two inbred strains (BALB/c and C57BL/6) were housed under either minimal husbandry conditions (MH: no cage enrichment, infrequent handling and a period of individual housing) or enriched husbandry conditions (EH: with cage enrichment, frequent handling and social housing at all times). One mouse in each cage was implanted with a radio-telemetry transmitter for measuring heart rate (HR) and body temperature (BT). The animals were subjected to intraperitoneal injections or short periods of restraint. In addition to telemetry measurements, thymus weight and tyrosine hydroxylase (TH) activity were assessed. It was found that individual housing under MH conditions, as compared with social housing under EH conditions, elevated both basal HR and BT, and significantly elevated the relative recovery time following routine experimental procedures. Thymus weight and TH activity suggested a long-term stress response under MH conditions following individual housing, although the influence of transmitter implantation and (repeated) acute stress remains to be investigated. The results emphasise that husbandry conditions should be taken into account when evaluating physiological measures after routine procedures.
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Fontana, Paula A., Carolina N. Zanuzzi, Claudio G. Barbeito, Eduardo J. Gimeno, and Enrique L. Portiansky. "Thymic atrophy in cattle poisoned with Solanum glaucophyllum." Pesquisa Veterinária Brasileira 29, no. 3 (March 2009): 266–74. http://dx.doi.org/10.1590/s0100-736x2009000300014.

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Solanum glaucophyllum (Sg) [= S. malacoxylon] is a calcinogenic plant inducing "Enzootic Calcinosis" in cattle. The 1,25-dihydroxyvitamin D3, its main toxic principle, regulates bone and calcium metabolism and also exerts immunomodulatory effects. Thymocyte precursors from bone marrow-derived progenitor cells differentiate into mature T-cells. Differentiation of most T lymphocytes is characterized not only by the variable expression of CD4/CD8 receptor molecules and increased surface density of the T cell antigen receptor, but also by changes in the glycosylation pattern of cell surface glycolipids or glycoproteins. Thymocytes exert a feedback influence on thymic non-lymphoid cells. Sg-induced modifications on cattle thymus T-lymphocytes and on non-lymphoid cells were analysed. Heifers were divided into 5 groups (control, intoxicated with Sg during 15, 30 or 60 days, and probably recovered group). Histochemical, immunohistochemical, lectinhistochemical and morphometric techniques were used to characterize different cell populations of the experimental heifers. Sg-poisoned heifers showed a progressive cortical atrophy that was characterized using the peanut agglutinin (PNA) lectin that recognizes immature thymocytes. These animals also increased the amount of non-lymphoid cells per unit area detected with the Picrosirius technique, WGA and DBA lectins, and pancytokeratin and S-100 antibodies. The thymus atrophy found in intoxicated animals resembled that of the physiological aging process. A reversal effect on these changes was observed after suppression of the intoxication. These findings suggest that Sg-intoxication induces either directly, through the 1,25-dihydroxyvitamin D3 itself, or indirectly through the hypercalcemia, the observed alteration of the thymus.
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8

Sheremetyeva, Anna S., Natalya A. Durnova, and Yulia G. Chernysheva. "Effect of <i>Thymus marschallianus</i> extract on lipid peroxidation processes <i>in vivo</i> and <i>in vitro</i> experiments." Aspirantskiy Vestnik Povolzhiya 21, no. 5-6 (May 15, 2021): 127–31. http://dx.doi.org/10.55531/2072-2354.2021.21.3.127-131.

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BACKGROUND: Currently, fundamental and experimental data confirming the role of free radicals in physiological and pathological processes have been accumulated. The literature describes conflicting information about the effect of antioxidants on the organism: they are able to protect not only normal cells from the alterative effect of free radicals, but also tumor cells, thereby supporting the survival and growth of the latter. Therefore, the study of the effect of Thymus marchallianus extract on the processes of lipoperoxidation in vivo against the background of the tumor process is relevant. AIM: To study the effect of Thymus marchallianus extract on the quantity of lipid peroxidation intermediates in the blood plasma of mongrel white rats with liver cancer PC-1 and compare with in vivo antioxidant activity. MATERIALS AND METHODS: The object of research was the dried Thymus marchallianus grass. Water and alcohol extracts were used in the experiment. Fifteen male white mongrel rats with a tumor were included in the experiment: the first group was intact, the second group received the water extract of Thymus marchallianus, and the third group received the alcohol extract of Thymus marchallianus. The activity of lipoperoxidation processes was evaluated, the content of intermediate lipid peroxidation intermediates malon dialdehyde, lipid hydroperoxides and medium-mass molecules in the blood plasma of experimental rats were estimated by means of conventional spectrophotometric methods. Determination of the antioxidant activity of the infusion and alcohol extraction in the in vitro experiment was carried out by the titrimetric method. RESULTS: In the control groups and the group of animals that received intraperitoneal water and alcohol extracts of Thymus marchallianus, increase in the intermediate products of lipid peroxidation was not revealed. The amount of malon dialdehyde, lipid hydroperoxides and medium-mass molecules in the blood plasma of experimental rats did not differ significantly from the level of similar indicators of intact animals. In the in vitro experiment, water and alcohol extracts from raw Thymus marchallianus showed antioxidant activity. CONCLUSIONS: For the first time, the experiment was conducted to study the effect of water and water-alcohol extracts of Thymus marchallianus on lipoperoxidation processes in mongrel white rats with alveolar liver cancer PC-1. The activity of formation of intermediate products of lipid peroxidation did not change, since their content in the blood plasma of experimental animals did not differ from the level of similar indicators of intact animals. In vitro the infusion and alcohol extract demonstrated antioxidant activity.
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9

Mahdavi, Atiyeh, Parviz Moradi, and Andrea Mastinu. "Variation in Terpene Profiles of Thymus vulgaris in Water Deficit Stress Response." Molecules 25, no. 5 (February 28, 2020): 1091. http://dx.doi.org/10.3390/molecules25051091.

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Thyme (Thymus spp.) volatiles predominantly consisting of monoterpenes and sesquiterpenes, serve as antimicrobial, antiseptic and antioxidant in phytomedicine. They also play a key role in plants as secondary metabolites via their potential role against herbivores, attracting pollinators and abiotic stress tolerance. Plant volatiles are affected by different environmental factors including drought. Here, the effect of prolonged water deficit stress on volatile composition was studied on the sensitive and tolerant thyme plant cultivars (T. vulgaris Var. Wagner and T. vulgaris Var. Varico3, respectively). Volatile sampling along with morpho–physiological parameters such as soil moisture, water potential, shoot dry weight, photosynthetic rate and water content measurements were performed on one-month-old plants subsequent to water withholding at 4-day intervals until the plants wilted. The tolerant and sensitive plants had clearly different responses at physiological and volatile levels. The most stress-induced changes on the plants’ physiological traits occurred in the photosynthetic rates, where the tolerant plants maintained their photosynthesis similar to the control ones until the 8th day of the drought stress period. While the analysis of the volatile compounds (VOCs) of the sensitive thyme plants displayed the same pattern for almost all of them, in the tolerant plants, the comparison of the pattern of changes in the tolerant plants revealed that the changes could be classified into three separate groups. Our experimental and theoretical studies totally revealed that the most determinant compounds involved in drought stress adaptation included α-phellandrene, O-cymene, γ-terpinene and β-caryophyelene. Overall, it can be concluded that in the sensitive plants trade-off between growth and defense, the tolerant ones simultaneously activate their stress response mechanism and continue their growth.
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10

Rooman, R., G. Koster, R. Bloemen, R. Gresnigt, and SC van Buul-Offers. "The effect of dexamethasone on body and organ growth of normal and IGF-II-transgenic mice." Journal of Endocrinology 163, no. 3 (December 1, 1999): 543–52. http://dx.doi.org/10.1677/joe.0.1630543.

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The physiological role of IGF-II remains unclear but there is evidence for a role in postnatal growth, the growth of the thymus and bone homeostasis. Glucocorticoids have many effects that are opposite to the effects of IGF-II such as growth retardation, osteoporosis and thymic involution. We therefore wondered whether IGF-II overexpression in transgenic mice might counteract some of the growth inhibitory effects of the glucocorticoid, dexamethasone (DXM). In a dose-finding study in normal mice, 20 microg DXM/day caused a significant growth delay. The various organs had a different susceptibility to the growth inhibitory effects of DXM. Most affected were thymus and spleen, followed by liver, skeletal muscle and lumbar vertebrae. The weights of the kidney, tibia, and humerus were not significantly diminished. In a second experiment, the effects of DXM in normal and IGF-II-transgenic animals were compared. The IGF-II serum levels in the transgenic animals were more than 40-fold increased compared with control mice and were decreased by 35% in the DXM-treated group. IGF-I serum levels were identical in both mouse strains and rose slightly after DXM administration in controls. Transgenic mice had higher levels of IGF binding protein species of apparent molecular masses of 41.5 kDa, 30 kDa, and 26.5 kDa. DXM reduced the 24 kDa band in both mice strains. In addition it reduced the bands at 38.5 kDa and 26.5 kDa but only in the transgenic animals. The effect of DXM on body growth was similar in normal and IGF-II-transgenic mice. The weight reduction of the various organs caused by DXM was similar in both types of mice except for the skeleton. The weight of the tibia and the humerus were significantly higher in the DXM-treated transgenic mice. In conclusion, we speculate that overexpression of IGF-II in mice partially protects bone from the osteopenic effects of glucocorticoids.
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Dissertations / Theses on the topic "Thymus Physiological effect"

1

Riley, Henry Drinker. "The characterization of the induction of lipocortin I by administration of dexamethasone and thyroid hormone in a thymic epithelial cell lne." Thesis, 1990. http://hdl.handle.net/10125/9372.

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