Academic literature on the topic 'Throat Diseases Treatment'

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Journal articles on the topic "Throat Diseases Treatment"

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Kolesnikova, O. M., S. A. Karpishchenko, and Y. V. Legkova. "ANTI-INFLAMMATORY THERAPY OF THROAT DISEASES." Folia Otorhinolaryngologiae et Pathologiae Respiratoriae 25, no. 3 (2019): 53–59. http://dx.doi.org/10.33848/foliorl23103825-2019-25-3-53-59.

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Sore throat is one of the most common complaints faced by doctors of various specialties. This symptom accompanies many diseases of the pharynx and larynx, and may be a manifestation of certain diseases that are not associated with the respiratory tract. When choosing therapy, it is necessary by doctors to rationally use the criteria for the appointment of systemic antibiotic therapy. However, local anti-inflammatory therapy as a symptomatic treatment should be selected before accurate confirmation of the etiology of the disease. This provides patients with a quick return to an active life and an improvement in the quality of life in general. The article discusses the etiology and pathogenesis of pain in diseases of the pharynx, modern diagnostic methods and optimal tactics for treating patients. As a symptomatic treatment, to reduce inflammation in the pharynx, the drug Vertum LOR, which belongs to the group of non-steroidal anti-inflammatory drugs of local action, may contain benzidamine as an active substance.
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Gerasimenko, M. Yu, T. N. Zaytseva, and I. S. Evstigneeva. "Physiotherapy of the ear, nose and throat diseases." Fizioterapevt (Physiotherapist), no. 6 (November 20, 2020): 66–79. http://dx.doi.org/10.33920/med-14-2012-08.

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The article provides a review of the literature, allowing to give a historical basis for the emergence of modern approaches to the physiotherapeutic treatment of ENT diseases. Several main highly effective directions of non-pharmacological action in ENT pathology are presented. Issues of physiotherapeutic treatment, which are focused on correcting complications of the disease or adverse reactions, are discussed. The indications are given for various methods of physiotherapeutic treatment in the pathology of the ENT organs.
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&NA;. "DELAYED TREATMENT FOR STREP THROAT." Pediatric Infectious Disease Journal 6, no. 12 (December 1987): 1140. http://dx.doi.org/10.1097/00006454-198706120-00018.

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&NA;. "DELAYED TREATMENT FOR STREP THROAT." Pediatric Infectious Disease Journal 6, no. 12 (December 1987): 1140. http://dx.doi.org/10.1097/00006454-198712000-00018.

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Petrovskaya, M. I. "TREATMENT OF ACUTE INFLAMMATORY DISEASES ACCOMPANIED BY THROAT IRRITATION AND PAIN." Pediatric pharmacology 10, no. 4 (August 14, 2013): 145. http://dx.doi.org/10.15690/pf.v10i4.769.

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Дєєва, Ю. В. "Effective treatment of inflammatory viral diseases of the throat and larynx." Family Medicine, no. 1(69) (January 23, 2017): 100–101. http://dx.doi.org/10.30841/2307-5112.1(69).2017.103210.

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Thirumazhisi Sachithanandam, Sangeetha. "Rising Methicillin-ResistantStaphylococcus aureusInfections in Ear, Nose, and Throat Diseases." Case Reports in Otolaryngology 2014 (2014): 1–3. http://dx.doi.org/10.1155/2014/253945.

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The increasing incidence of methicillin-resistantStaphylococcus aureusinfections (MRSA) in ENT diseases is becoming a big clinical concern. Here two patients are described who developed MRSA infections presented with unusual post-FESS epistaxis and postmastoidectomy perichondrial abscess and failed treatment with broad spectrum intravenous antibiotics. Following treatment with oral linezolid combined with local mupirocin dressing both patients fully recovered.
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Osipovsky, V. M. "On the treatment and prevention of angina thymol." Kazan medical journal 29, no. 5-6 (January 12, 2022): 469–70. http://dx.doi.org/10.17816/kazmj89608.

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Chernetska, S. B., and N. M. Beley. "ANALYSIS OF THE PHARMACEUTICAL MARKET OF MEDICINES FOR THE TREATMENT OF THROAT DISEASES." Fitoterapia 1, no. 1 (2019): 34–37. http://dx.doi.org/10.33617/2522-9680-2019-1-34.

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Uraskulovа, B. B., and A. O. Gyusan. "Experience in the use of the drug „Aqua Maris Strong for Throat“ in the complex treatment of inflammatory diseases of the larynx." Russian Otorhinolaryngology 21, no. 3 (2022): 148–54. http://dx.doi.org/10.18692/1810-4800-2022-3-148-154.

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Currently, the treatment of patients with inflammatory diseases of the larynx in most cases is multi-stage, long-term, and requires numerous techniques using specialized equipment. In the daily work of an otorhinolaryngologist with inflammatory diseases of the larynx, drugs are most often used in the form of injections or oral use. Aerosol therapy enables fast and effective therapeutic action with the use of a relatively small dose of the drug and a significant reduction in the negative systemic effect. An effective means of treating diseases of the upper respiratory tract is irrigation and inhalation therapy using sea water, which moisturizes dry mucous membranes, promotes rapid softening and removal of crusts. To establish the therapeutic efficacy of the use of Aqua Maris Strong for Throat in the complex treatment of inflammatory diseases of the larynx, 76 patients suffering from inflammatory diseases of the larynx were selected, who were divided into the main and control groups of the study. Patients of the main group as part of complex therapy for inflammatory diseases of the larynx received inhalation administration of the drug "Aqua Maris Strong for Throat ". The inhalation procedure consisted of 2 inhalations lasting 10 minutes, 2 times a day. The control group of patients – 37 patients received traditional etiotropic treatment of inflammatory diseases of the larynx. As the study showed, in patients who received inhalation administration of the Aqua Maris Strong for Throat preparation as part of the complex therapy of inflammatory diseases of the larynx, positive dynamics of complaints, normalization of the laryngostroboscopic picture were noted faster than in patients of the control group. The advantage of therapy using Aqua Maris Strong for Throat was also confirmed by the restoration of cytopathological changes in local cellular protection, in the form of a decrease in signs of deepithelialization, mucociliary insufficiency, phagocytosis of cellular elements, a decrease in the concentration of pathological flora on the laryngeal mucosa in a shorter period of time than in patients in the control group.
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Dissertations / Theses on the topic "Throat Diseases Treatment"

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王錦文. "中醫藥慢性喉炎的研究進展." HKBU Institutional Repository, 2008. http://repository.hkbu.edu.hk/etd_ra/961.

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Books on the topic "Throat Diseases Treatment"

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Anṣārī, Muḥammad Yūsuf. Uz̲n, anf va ḥalq: Maʻ imrāz̤-i lisān, asnān aur lathah. Naʾī Dihlī: Iʻjāz Pablishing Hāʾūs, 2004.

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Blonigen, Julie A. Treatment of vocal hoarseness in children: Julie A. Blonigen. 2nd ed. Austin, Tex: Pro-Ed, 2000.

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United States. Congress. House. Committee on International Relations. Infectious diseases: A growing threat to America's health and security : hearing before the Committee on International Relations, House of Representatives, One Hundred Sixth Congress, second session, June 29, 2000. Washington: U.S. G.P.O., 2000.

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United States. Congress. House. Committee on International Relations. Infectious diseases: A growing threat to America's health and security : hearing before the Committee on International Relations, House of Representatives, One Hundred Sixth Congress, second session, June 29, 2000. Washington: U.S. G.P.O., 2000.

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Reagan, Ronald. AIDS initiatives: Message from the President of the United States transmitting a 10-point action plan to respond to the public health threat posed by the human immunodeficiency virus. Washington: U.S. G.P.O., 1988.

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Progress since September 11th: Protecting public health and safety of the responders and residents : hearing before the Subcommittee on National Security, Emerging Threats, and International Relations of the Committee on Government Reform, House of Representatives, One Hundred Ninth Congress, second session, September 8, 2006. Washington: U.S. G.P.O., 2007.

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Office, General Accounting. VA health care: Further efforts needed to improve hepatitis C testing for at-risk veterans : report to the Chairman, Subcommittee on National Security, Emerging Threats, and International Relations, Committee on Government Reform, House of Representatives. Washington, D.C: United States General Accounting Office, 2003.

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Parker, Charles Arthur. A Guide to Diseases of the Nose and Throat and Their Treatment. Arkose Press, 2015.

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Lydiatt, MD William M., and MD Perry Johnson. Cancers of the Mouth and Throat: A Patient's Guide to Treatment. Addicus Books, 2000.

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Ingals, E. Fletcher. Lectures On The Diagnosis And Treatment Of Diseases Of The Chest, Throat And Nasal Cavities. Kessinger Publishing, LLC, 2007.

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Book chapters on the topic "Throat Diseases Treatment"

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Ravi Sankar, M., M. Arulalan, and Amit K. Keshri. "Biofilm-Mediated Diseases of the Ear, Nose, and Throat (ENT)." In Biofilms in Human Diseases: Treatment and Control, 127–35. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-30757-8_9.

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Vural, Elif Hilal, and Ismail Mert Vural. "Reliability of Frequently Used Ear, Nose, and Throat Drugs During Pregnancy and the Postpartum Period." In ENT Diseases: Diagnosis and Treatment during Pregnancy and Lactation, 375–410. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-05303-0_28.

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Littmann, Jasper, A. M. Viens, and Diego S. Silva. "The Super-Wicked Problem of Antimicrobial Resistance." In Ethics and Drug Resistance: Collective Responsibility for Global Public Health, 421–43. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-27874-8_26.

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Abstract Antimicrobial resistance (AMR) – the progressive process by which microbes, such as bacteria, through evolutionary, environmental and social factors develop the ability to become resistant to drugs that were once effective at treating them – is a threat from which no one can escape. It is one of the largest threats to clinical and global health in the twenty-first century – inflicting monumental health, economic and social consequences. All persons locally and globally, and even all future persons yet to come into existence, all suffer the shared, interdependent vulnerability to this threat that will have a substantial impact on all aspects of our lives. For example, while reliable data are hard to find, the European Centre for Disease Prevention and Control (ECDC) has conservatively estimated that, in Europe alone, AMR causes additional annual cost to health care systems of at least €1.5 billion, and is responsible for around 25,000 deaths per year. Furthermore, AMR significantly increases the cost of treating bacterial infections with an increase in length of hospital stays and average number of re-consultations, as well as the resultant lost productivity from increased morbidity. With a combined cost of up to $100 trillion to the global economy – pushing a further 28 million people into extreme poverty – this is one of the most pressing challenges facing the world. Most troublingly, if we do not succeed in diminishing the progression of AMR, there is the very real potential for it to threaten common procedures and treatments of modern medicine, including the safety and efficacy of surgical procedures and immunosuppressing chemotherapy. Some experts are warning that we may soon be ushering in a post-antibiotic area.
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Sussman, Joel L., and Israel Silman. "Structural Studies on Acetylcholinesterase and Paraoxonase Directed Towards Development of Therapeutic Biomolecules for the Treatment of Degenerative Diseases and Protection Against Chemical Threat Agents." In NATO Science for Peace and Security Series A: Chemistry and Biology, 183–99. Dordrecht: Springer Netherlands, 2009. http://dx.doi.org/10.1007/978-90-481-2339-1_12.

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Ho, Calvin W. L., and Tsung-Ling Lee. "Global Governance of Anti-microbial Resistance: A Legal and Regulatory Toolkit." In Ethics and Drug Resistance: Collective Responsibility for Global Public Health, 401–20. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-27874-8_25.

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Abstract Recognizing that antimicrobial resistance (AMR) poses a serious threat to global public health, the World Health Organization (WHO) has adopted a Global Action Plan (GAP) at the May 2015 World Health Assembly. Underscoring that systematic misuse and overuse of drugs in human medicine and food production is a global public health concern, the GAP-AMR urges concerted efforts across governments and private sectors, including pharmaceutical industry, medical professionals, agricultural industry, among others. The GAP has a threefold aim: (1) to ensure a continuous use of effective and safe medicines for treatment and prevention of infectious diseases; (2) to encourage a responsible use of medicines; and (3) to engage countries to develop their national actions on AMR in keeping with the recommendations. While the GAP is a necessary step to enable multilateral actions, it must be supported by effective governance in order to realize the proposed aims. This chapter has a threefold purpose: (1) To identify regulatory principles embedded in key WHO documents relating to AMR and the GAP-AMR; (2) To consider the legal and regulatory actions or interventions that countries could use to strengthen their regulatory lever for AMR containment; and (3) To highlight the crucial role of the regulatory lever in enabling other levers under a whole-of-system approach. Effective AMR containment requires a clearer understanding of how the regulatory lever could be implemented or enabled within health systems, as well as how it underscores and interacts with other levers within a whole-of-system approach.
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Céspedes, Reina, Noel Arrieta, Miguel Barquero, Ana Abdelnour, Nielen Stephan, and Ingelbretch Ivan. "Determination of radiosensitivity of Coffea arabica var. 'Venecia' seeds to gamma-ray irradiation." In Mutation breeding, genetic diversity and crop adaptation to climate change, 320–25. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781789249095.0033.

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Abstract Coffee is one of the most commercially available raw materials, being the tropical product with the highest market value in the world. In Costa Rica it is the third most important product for agricultural exports and provides the main income for many families in the country. However, coffee is under threat due to coffee leaf rust disease (CLR). Mutation breeding in coffee is a promising approach to develop new varieties resistant to CLR. As a new technology for coffee, basic tests related to mutation induction need to be done. The plant material used was Coffea arabica var. 'Venecia' seeds, with a moisture content of 27.3%. The applied irradiation doses were 0, 80, 100, 120, 140, 160 and 180 Gy. For each treatment, three replicates of 200 g were used, with a seed number range of 765-808 units per replicate. The irradiated seeds were planted on the same day. Eighty days after treatment the number of seedlings was quantified, the hypocotyl height and radicle length were measured and the opening of cotyledons was determined for each dose. The effects of the radiation doses on seed germination frequency were recorded. At the dose of 80 Gy, germination was reduced over the control by 9.65%, at 100 Gy by 34.06%, at 120 Gy by 52.76%, at 140 Gy by 60.24%, at 160 Gy by 65.56% and at 180 Gy by 75.40%. Seedling growth was affected and a delay in opening of the cotyledons was observed at higher doses. This radiosensitivity test, based on seed germination as compared with unirradiated control, revealed that the LD50 for the variety tested is in the range 100-120 Gy experimentally, and according to the regression is 125 ± 30 Gy. This dose will be used for further bulk experiments and is of great importance, because the LD50 is considered as the range where the appearance of useful mutations in breeding programmes is favoured. The establishment of these parameters is a necessary advance to continue with measurements of genetic and phenotypical parameters to implement mutation breeding in coffee looking for new sources of resistance against CLR.
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"METHODS OF EXAMINATION. SYMPTOMS AND GENERAL TREATMENT." In Diseases of the Nose, Throat and Ear, 20–31. Elsevier, 2013. http://dx.doi.org/10.1016/b978-1-4831-6685-8.50009-3.

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"DISEASES OF THE PAROTID GLAND, AND THEIR TREATMENT INTRODUCTION." In Ear Nose & Throat for Lawyers, 531–38. Routledge-Cavendish, 1997. http://dx.doi.org/10.4324/9781843143598-157.

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"TREATMENT OF CHRONIC SUPPURATION IN THE PARANASAL SINUSES." In Diseases of the Nose, Throat and Ear, 83–92. Elsevier, 2013. http://dx.doi.org/10.1016/b978-1-4831-6685-8.50019-6.

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STEVENSON, R. SCOTT. "THE NON-SURGICAL TREATMENT OF DEAFNESS." In Modern Trends in Diseases of the Ear, Nose and Throat, 110–22. Elsevier, 2013. http://dx.doi.org/10.1016/b978-1-4831-6732-9.50012-9.

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Conference papers on the topic "Throat Diseases Treatment"

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"Neurological symptoms of corona virus disease." In 4th International Conference on Biological & Health Sciences (CIC-BIOHS’2022). Cihan University, 2022. http://dx.doi.org/10.24086/biohs2022/paper.836.

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Corona virus disease is an infectious disease induced by a family of viruses that can cause common cold and severe acute respiratory syndrome (SARS).This research work was designed to shed light on the different presentation forms, especially the unusual ones of the disease as an attempt to make early diagnosis for better and efficient treatment and prevention of the disease.A sample of 203 subjects who have had corona disease were questioned about the symptoms they were complaining of during the illness. Correlation coefficient study was conducted to declare the relationship between the different symptoms especially the unusual ones and the disease, among the symptoms themselves, certain symptoms with the age group, as well as the gender.The results showed positive correlation between many of the usual symptoms and the disease for instance, fever, headache, cough, dyspnea, malaise, muscle and joint pain, dizziness, loss of smell and appetite, running nose, sore throat, nausea, vomiting, and diarrhea. No significant correlation could be detected with the unusual symptoms like, elevated blood pressure, conjunctival congestion, amnesia, and decreased concentration, skin rash, loss of consciousness, intestinal colic and gastric pain.According to the available results no specific symptom could be attributed to a given age group or gender with the exception of the neurological symptoms in the form of amnesia, loss of consciousness, and decreased concentration. These findings were found to be firmly correlated with the severity of fever. The authors postulate that these symptoms can be attributed to the temporary reduction in the number of neurotransmitters molecules of the brain. Further work is needed to provide evidence in support of this postulation. In conclusion, for early diagnosis and therefore to achieve efficient treatment of corona disease, unusual presentation must be kept in mind. Fever must be delt with seriously and effectively to prevent or minimize the development of neurological symptoms. Using all means of audio, video, and social media to spread the information about the disease will have a crucial role in slowing the spread of the disease especially the new strains.
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Lobis, Yusuf Bachtiyar, Bhisma Murti, and Hanung Prasetya. "Influences of Peer Support Group and Psychosocio- Economic Determinants on Treatment Compliance in Hiv/Aids Patients in Sragen, Central Java." In The 7th International Conference on Public Health 2020. Masters Program in Public Health, Universitas Sebelas Maret, 2020. http://dx.doi.org/10.26911/the7thicph.02.59.

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Background: Adherence to treatment is important to reduce viral replication, improve clinical and immunological conditions, reduce the risk of developing ARV resistance, and reduce the risk of HIV transmission. Peer support is suspected to be one of the factors driving drug intake adherence in patients with chronic disease. This study aimed to examine the influences of peer support and psychosocio-economic determinants on treatment compliance in HIV/AIDS patients. Subjects and Method: This was a case control design study conducted in Sragen, Central Java, Indonesia. A sample of 200 people with HIV/AIDS (PLWH) was selected by fixed disease sampling. The dependent variable was treatment compliance. The independent variables were knowledge toward HIV/AIDS, perceived benefit, perceived belief, perceived threat, perceived susceptibility, perceived seriousness, perceived barrier, attitude, indirect experience, family support, and peer support. The data were obtained from medical record and questionnaire. The data were analyzed by a multiple logistic regression run on Stata 13. Results: Treatment compliance increased with strong peer support (b= 1.34; 95% CI= 0.31 to 2.38; p= 0.011), strong family support (b= 1.09; 95% CI= 0.16 to 2.02; p= 0.021), knowledge toward HIV/AIDS (b= 1.65; 95% CI= 0.67 to 2.64; p= 0.001), high perceived benefit (b= 1.23; 95% CI= 0.28 to 2.18; p= 0.011), perceived belief (b= 2.05; 95% CI= 0.98 to 3.12; p<0.001), and high perceived threat (b= 1.22; 95% CI= 0.30 to 2.13; p= 0.009). Treatment compliance decreased with negative attitude (b= -2.47; 95% CI= -3.58 to -1.37; p <0.001), low perceived susceptibility (b= -1.26; 95% CI= -2.24 to – 0.27; p= 0.012), low perceived seriousness (b= -1.11; 95% CI= -2.06 to -0.16; p=0.021), high perceived barrier (b= -1.76; 95% CI= -2.81 to -0.70; p= 0.001), and indirect experience (b= -1.10; 95% CI= -2.05 to -0.14; p= 0.024). Conclusion: Treatment compliance increases with strong peer support, strong family support, high knowledge toward HIV/AIDS, high perceived benefit, perceived belief, and high perceived threat. Treatment compliances decrease with negative attitude, low perceived susceptibility, low perceived seriousness, high perceived barrier, and indirect experience. Keywords: HIV/AIDS, treatment compliance, peer support, psychosocial economy Correspondence: Yusuf Bachtiyar Lobis. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: bachtiyar03@gmail.com. Mobile: +628111388841. DOI: https://doi.org/10.26911/the7thicph.02.59
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Liu, Chengcheng. "Strategies on healthy urban planning and construction for challenges of rapid urbanization in China." In 55th ISOCARP World Planning Congress, Beyond Metropolis, Jakarta-Bogor, Indonesia. ISOCARP, 2019. http://dx.doi.org/10.47472/subf4944.

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In the past 40 years, China has experienced the largest and fastest urbanization development in the world. The infrastructure, urban environment and medical services of cities have been improved significantly. The health impacts are manifested in the decrease of the incidence of infectious diseases and the significant increase of the life span of residents. However, the development of urbanization in China has also created many problems, including the increasing pollution of urban environment such as air, water and soil, the disorderly spread of urban construction land, the fragmentation of natural ecological environment, dense population, traffic congestion and so on. With the process of urbanization and motorization, the lifestyle of urban population has changed, and the disease spectrum and the sequence of death causes have changed. Chronic noncommunicable diseases have replaced acute infectious diseases and become the primary threat to urban public health. According to the data published by the famous medical journal The LANCET on China's health care, the economic losses caused by five major non-communicable diseases (ischemic heart disease, cerebrovascular disease, diabetes mellitus, breast cancer and chronic obstructive pulmonary disease) will reach US$23 trillion between 2012 and 2030, more than twice the total GDP of China in 2015 (US$11.7 trillion). Therefore, China proposes to implement the strategy of "Healthy China" and develop the policy of "integrating health into ten thousand strategies". Integrate health into the whole process of urban and rural planning, construction and governance to form a healthy, equitable and accessible production and living environment. China is building healthy cities through the above four strategies. The main strategies from national system design to local planning are as follows. First of all, the top-level design of the country. There are two main points: one point, the formulation of the Healthy China 2030 Plan determines the first batch of 38 pilot healthy cities and practices the strategy of healthy city planning; the other point, formulate and implement the national health city policy and issue the National Healthy City. The evaluation index system evaluates the development of local work from five aspects: environment, society, service, crowd and culture, finds out the weak links in the work in time, and constantly improves the quality of healthy city construction. Secondly, the reform of territorial spatial planning. In order to adapt to the rapid development of urbanization, China urban plan promote the reform of spatial planning system, change the layout of spatial planning into the fine management of space, and promote the sustainable development of cities. To delimit the boundary line of urban development and the red line of urban ecological protection and limit the disorderly spread of urban development as the requirements of space control. The bottom line of urban environmental quality and resource utilization are studied as capacity control and environmental access requirements. The grid management of urban built environment and natural environment is carried out, and the hierarchical and classified management unit is determined. Thirdly, the practice of special planning for local health and medical distribution facilities. In order to embody the equity of health services, including health equity, equity of health services utilization and equity of health resources distribution. For the elderly population, vulnerable groups and patients with chronic diseases, the layout of community health care facilities and intelligent medical treatment are combined to facilitate the "last kilometer" service of health care. Finally, urban repair and ecological restoration design are carried out. From the perspective of people-oriented, on the basis of studying the comfortable construction of urban physical environment, human behavior and the characteristics of human needs, to tackle "urban diseases" and make up for "urban shortboard". China is building healthy cities through the above four strategies. Committed to the realization of a constantly developing natural and social environment, and can continue to expand social resources, so that people can enjoy life and give full play to their potential to support each other in the city.
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de Paor, A. M., and M. M. Lowery. "Can control theory throw light on Parkinson's Disease and its treatment with deep brain stimulation?" In IET Irish Signals and Systems Conference (ISSC 2009). IET, 2009. http://dx.doi.org/10.1049/cp.2009.1681.

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Seitz, R., G. Pratorius, R. Blanke, and B. B. Strauer. "Increase of Thrombin-Antithrombin III (TAT) Complex Plasma Levels in Thromboembolic Diseases during Thrombolysis." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643676.

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Recently an enzyme immuno assay of thrombin-antithrombinlll complex (TAT) plasma levels was developed by PELZER et al. (Thromb. Haemost. 54:24,1985). This test appears to be useful in the detection of intravasal thrombin generation, since all of 17 patients (pts.) with pulmonary embolism and 15 of 16 pts. with deep vein thrombosis (DVT) showed elevated values above 3 ng/ml.In 9 pts. with acute myocardial infarction (AMI) the TAT levels increased significantly (p 0.001) 3 to 6 hours after thrombolytic therapy with 1.5 million units streptokinase (SK) over 30 minutes. A concomitant increase of fibrinopeptide A (FPA) levels (p=0.048) was observed. In contrast, 8 AMI pts. treated with heparin showed an insignificant increase of TAT and FPA. In 7 DVT pts. the TAT levels rose significantly (p 0.001) within 6 hours after start of urokinase (UK) infusion, while the FPA levels were enhanced prior to treatment and showed no further increase.In order to assess the in vitro effects of SK and UK on TAT levels, clots obtained by recalcification of citrated plasma were incubated in heparin (2 units/ml) plasma. An increase of TAT occurred after addition of SK or UK, which was less pronounced when the clots were rinsed extensivly or squeezed before incubation. When SK or UK were added to plasma in the absence of a clot, still a small increase of TAT occurred which was absent in saline controls.The data suggest that SK and UK action is associated with the generation of TAT complexes. In vivo, thrombin or thromboplastic material might be released by enhanced "wash out" from the recanalized coronary artery or from the reperfused in-farcted myocardium. Thrombin might also be released from binding sites on fibrin clots or fibrinogen. It is conceivable that these findings contribute to the understanding of reocclusion of infarct vessels after thrombolytic therapy. This points to the importance of careful anticoagulation in patients receiving thrombolytic therapy.
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Fujimori, T., T. Saeki, K. Harada, M. Sato, and N. Ohshima. "ANTI-THROMBOTIC EFFECTS OF E-5510 IN EXPERIMENTAL THROMBOSIS MODELS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643429.

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A new agent developed in our laboratory, 4-cyano-5,5-bis(4-methoxyphenyl)-4-pentenoic acid (E-5510), suppressed various human platelet functions in vitro. The compound also showed quite potent ex vivo anti-platelet effects in many experimentalanimals. It is well known that anti-platelet effects are not always parallel to anti-thrombotic effects. Thus, in order to predict the efficacy of E-5510 in thrombotic disorders, the anti-thrombotic effects were examined in 3 different animal models of thrombosis.(1) Anti-thrombotic effect in an extracorporeal shunt model Two hrs after oral administration of the drug to guinea pigs,an extracorporeal shunt between the right carotid artery and the left jugular vein was performed. The thrombus formation on a silk thread inserted in the shunt tube was quantitated by measuring the time from the onset of circulation to the stenosis of blood flow. E-5510 dose-dependently inhibited thrombus formation, the minimum effective dose being 0.03 mg/kg.(2) Effect on microthrombus formation in mesenteric arteriole In order to evaluate the effect on intravascular platelet thrombus formation, thrombosis was induced in vivo in mesenteric arteriole in guinea pigs with filtered light from a mercury lamp and an intravenous fluorescent dye in an intravital microscope system (M. Sato and N. Ohshima, Thromb. Res.,35, 319, 1984). The thrombus formation was quantitated by measuring the time taken for circulating platelets to begin to adhere to vessel wall and the time taken for blood flow to stop completely due to fully developed thrombus. Both the time required for platelet adhesion to vessel wall and for platelet thrombus formation were significantly prolonged after oral administration of E-5510.(3) Effect on pulmonary thromboembolism Acute pulmonary thromboembolism was induced in mice by a bolus intravenous injection of arachidonic acid, and mortality was determined 3 min later. E-5510 dose-dependently reduced pulmonary thromboembolic mortality, and its ED50 was 0.11 mg/kg. The results described above indicate thatE-5510 may have beneficial effects in clinical treatments of thrombotic disease.
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Liu, Y., J. Y. Ye, Y. X. Liu, and H. Y. Luo. "Flow Analysis in Upper Airway for an OSA Subject Before and After Surgery." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53340.

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Obstructive sleep apnea (OSA) is very common and can strike anyone at any age, even children. Yet still because of the lack of awareness by the public and healthcare professionals, the majority remain undiagnosed and therefore untreated, despite the fact that this serious disorder can have significant consequences. Untreated, sleep apnea can cause high blood pressure and other cardiovascular disease, memory problems, weight gain, impotency, and headaches [1]. OSA is caused by a blockage of the airway, usually when the soft tissue in the rear of the throat collapses and closes during sleep. With apnea event, the brain briefly arouses people with sleep apnea in order for them to resume breathing, but consequently sleep is extremely fragmented and of poor quality. Several surgical techniques may be used for OSA, and these include: uvulopalatopharngeoplasty (UP3), tonsillectomy and pharyngoplasty, uvulopalatal flap, laser and radiofrequency assisted uvulopalatal surgeries. The surgery involves removing the uvula and some of the surrounding soft palate. The idea behind the upper airway surgery is to eliminate the area of obstruction or to widen the airway so it does not occlude completely. However, the success rate is limited; for example, the UP3 helps in around 50% who have the surgery and in others it does not help at all or it helps only partially [2]. The post-operative complications after surgery are often the result of a dilemma during the operation of how much tissue to resect: too little is ineffective, yet too much may leave a patient with speech impedance and palatal stenosis, which can make OSA worse [3]. Therefore, accurate prediction of tissue reduction for this treatment is urgently needed.
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Nastase, Mihai-Claudiu, Alexandru Mitru, and Loredana Andreea Paun (Parnic). "The Social and Economic Impact of COVID 19 Pandemic on Museums. Case Study: „Princely Court” National Museum Ensemble." In International Conference Innovative Business Management & Global Entrepreneurship. LUMEN Publishing, 2020. http://dx.doi.org/10.18662/lumproc/ibmage2020/25.

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The new coronavirus (Covid-19) is one of the main challenges world today has to address. With no large scale availability vaccine yet, and more or less experimental medical treatments for curing the disease, we can safely say that we are still far behind a solution to this problem. This new pandemic is considered the biggest threat to the global economy since the Second World War and there is no aspects of human life have not been affected it, spiritual ones included. Its high contagiousness, as well as novelty, raised all kind of challenges and one of the main ones was our manner to produce answers, in early stages at least, this creating problem on its own and of its design. As well as all the other institutions, theatres, cinemas, concert halls, spaces of socialization and in the same time places of wonder, knowledge and spiritual enrichment the museums were heavily affected by the pandemic crisis, especially those who’s collections are not, but in very small proportion available, to the public through virtual media. Such a case is „Princely Court„ National Museums Ensemble from Targoviste, Dambovita County, Romania. The present paper proposes an overview of the highlights in institution′s activity the past years in comparison with how the pandemic crisis affected its activity in the past months and what were the responses given to keep the museum in the eye of the public. It will also try to summarize how and to what extent the activity went back to „normal” after the emergency state earlier imposed was lifted and how the visitors responded to the new realities.
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Reports on the topic "Throat Diseases Treatment"

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Bain, Luchuo Engelbert, and Darja Dobermann. Malaria, HIV and TB in the Democratic Republic of the Congo: Epidemiology, Disease Control Challenges and Interventions. Institute of Development Studies (IDS), March 2022. http://dx.doi.org/10.19088/k4d.2022.034.

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Malaria, human immune deficiency virus (HIV) and tuberculosis (TB) are leading causes of death and public health threat to millions in Democratic Republic of Congo (DRC). The DRC is the second most malaria affected sub-Saharan African country after Nigeria, with malaria being the leading cause of death in children under 5 years (Lechthaler et al., 2019). The HIV prevalence in the country in the adult population stands at 1%, with extensive variations by region (UNAIDS, 2021c). The DRC is considered a high burden country for TB and HIV infection (Linguissi et al., 2017). This rapid review emphasizes significant elements of the epidemiology of malaria, HIV, and TB in DRC, as well as limitations in prevention, detection, and treatment, and examines a few interventions that aim to address these limitations. Evidence utilised is a mixture of the most recent grey literature NGO (programme reports and related documents) literature supplemented by peer reviewed academic literature from the past five years and national survey data when available. Although the clinical disease aspects of malaria, HIV and TB are well-researched there is less research available on socio-demographic variation, disease control challenges and interventions targeting these in the DRC. This is part of a series of reports looking into Epidemiology of Malaria, human immune deficiency virus (HIV) and tuberculosis (TB) across a set of African Nations.
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Cahaner, Avigdor, Susan J. Lamont, E. Dan Heller, and Jossi Hillel. Molecular Genetic Dissection of Complex Immunocompetence Traits in Broilers. United States Department of Agriculture, August 2003. http://dx.doi.org/10.32747/2003.7586461.bard.

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Objectives: (1) Evaluate Immunocompetence-OTL-containing Chromosomal Regions (ICRs), marked by microsatellites or candidate genes, for magnitude of direct effect and for contribution to relationships among multiple immunocompetence, disease-resistance, and growth traits, in order to estimate epistatic and pleiotropic effects and to predict the potential breeding applications of such markers. (2) Evaluate the interaction of the ICRs with genetic backgrounds from multiple sources and of multiple levels of genetic variation, in order to predict the general applicability of molecular genetic markers across widely varied populations. Background: Diseases cause substantial economic losses to animal producers. Emerging pathogens, vaccine failures and intense management systems increase the impact of diseases on animal production. Moreover, zoonotic pathogens are a threat to human food safety when microbiological contamination of animal products occurs. Consumers are increasingly concerned about drug residues and antibiotic- resistant pathogens derived from animal products. The project used contemporary scientific technologies to investigate the genetics of chicken resistance to infectious disease. Genetic enhancement of the innate resistance of chicken populations provides a sustainable and ecologically sound approach to reduce microbial loads in agricultural populations. In turn, animals will be produced more efficiently with less need for drug treatment and will pose less of a potential food-safety hazard. Major achievements, conclusions and implications:. The PI and co-PIs had developed a refined research plan, aiming at the original but more focused objectives, that could be well-accomplished with the reduced awarded support. The successful conduct of that research over the past four years has yielded substantial new information about the genes and genetic markers that are associated with response to two important poultry pathogens, Salmonella enteritidis (SE) and Escherichia coli (EC), about variation of immunocompetence genes in poultry, about relationships of traits of immune response and production, and about interaction of genes with environment and with other genes and genetic background. The current BARD work has generated a base of knowledge and expertise regarding the genetic variation underlying the traits of immunocompetence and disease resistance. In addition, unique genetic resource populations of chickens have been established in the course of the current project, and they are essential for continued projects. The US laboratory has made considerable progress in studies of the genetics of resistance to SE. Microsatellite-marked chromosomal regions and several specific genes were linked to SE vaccine response or bacterial burden and the important phenomenon of gene interaction was identified in this system. In total, these studies demonstrate the role of genetics in SE response, the utility of the existing resource population, and the expertise of the research group in conducting such experiments. The Israeli laboratories had showed that the lines developed by selection for high or low level of antibody (Ab) response to EC differ similarly in Ab response to several other viral and bacterial pathogens, indicating the existence of a genetic control of general capacity of Ab response in young broilers. It was also found that the 10w-Ab line has developed, possibly via compensatory "natural" selection, higher cellular immune response. At the DNA levels, markers supposedly linked to immune response were identified, as well as SNP in the MHC, a candidate gene responsible for genetic differences in immunocompetence of chickens.
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