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Morrison, Lesley S. "Thimet oligopeptidase : gene expression and function." Thesis, Glasgow Caledonian University, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.404681.
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McCool, Suzan. "Regulation of thimet oligopeptidase gene expression in the male reproductive system." Thesis, Glasgow Caledonian University, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.285223.
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Lim, Eun Jeong. "STRUCTURAL AND FUNCTIONAL STUDIES OF SYNAPTIC ENZYMES." UKnowledge, 2006. http://uknowledge.uky.edu/gradschool_diss/259.
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Thimet oligopeptidase (TOP, EC 3.4.24.15) and neurolysin (EC 3.4.24.16) are zincdependent metallopeptidases that metabolize small bioactive peptides. The two enzymes share60 % sequence identity and their crystal structures demonstrate that they adopt nearly identicalfolds. They generally cleave at the same sites, but they recognize different positions on somepeptides, including neurotensin, a 13-residue peptide involved in modulation of dopaminergiccircuits, pain perception, and thermoregulation.On the basis of crystal structures and previous mapping studies, four residues(E469/R470, M490/R491, H495/N496, and R498/T499, TOP residues listed first) in thesubstrate-binding channel appear positioned to account for differences in specificity. TOPmutated to the neurolysin residues at all four position cleaves neurotensin at the neurolysin siteand neurolysin mutated to the TOP residues at all four sites cleaves at the TOP position. Using aseries of constructs mutated at only three sites, it was determined that only two of the mutations,E469/R470 and R498/T499, are required to swap the specificity of TOP and neurolysin. Theseresults were confirmed by testing the two mutation constructs, and either single mutant of TOPshown an intermediate specificity, cleaving at both sites.Crystal structures of the two mutation constructs of TOP and neurolysin unligandedforms, the mutations do not perturb local structure, but side chain conformations at theR498/T499 position differ from those of the mimicked enzyme. A model for differentialrecognition of neurotensin based on differences in surface charge distribution in the substratebinding sites is proposed. The model is supported by finding that reducing the positive charge onthe peptide results in cleavage at both hydrolysis sites.This dissertation also includes a description of the production and crystallization trials ofhuman neprilysin (E.C. 3.4.24.11), which will be used as another model system for studyingspecificity in metallopeptidases. In addition, the production and crystallization, and crystalcharacterization of human choline acetyltransferase (EC 2.3.1.6) is described.
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Gravi, Ellen Tihe [UNIFESP]. "Identificação de atividade metalo-oligopeptidásica Thimet-like em Paracoccidioides brasiliensis: um novo fator de patogenicidade fúngica?" Universidade Federal de São Paulo (UNIFESP), 2010. http://repositorio.unifesp.br/handle/11600/9696.
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Previous issue date: 2010-10-28Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Paracoccidioides brasiliensis (Pb), é uma micose sistêmica grave com formas aguda e crônica. As proteases ou peptidases são enzimas proteolíticas que ocorrem em todos os organismos e correspondem a 1-5% de seus conteúdos genéticos. Estas enzimas estão envolvidas em processos biológicos essenciais, como a coagulação sanguínea, morte celular e diferenciação de tecidos. Várias etapas proteolíticas importantes ocorrem durante a invasão metastática de tumores, assim como no ciclo de infecção de um grande número de vírus e microrganismos patogênicos. Um número reduzido de proteases do Pb já foram isoladas e caracterizadas, tampouco sua atividade durante o desenvolvimento da doença foi determinado, e até o momento, nenhuma atividade oligopeptidásica foi descrita nesse fungo. No presente trabalho foi demonstrada a presença de uma atividade metalo-peptidásica thimet oligopeptidase (TOP)-like no extrato citosólico de leveduras de P. brasiliensis, isolado 18 (Pb18). Nossos resultados mostraram a hidrólise do peptídeo com supressão intramolecular de fluorescência Abz-GFSPFRQ-EDDnp pelo extrato citosólico de leveduras de P. brasiliensis. Esse substrato é clivado preferencialmente pela TOP de mamíferos, e corroborando esse resultado, observou-se a inibição da hidrólise desse peptídeo por ο-fenantrolina e JA-2, inibidores seletivos de metalo-proteases e TOP, respectivamente. Utilizando-se peptídeos e inibidores seletivos para diferentes proteases, não se detectou a presença de atividade neurolisina-like ou neprilisina-like, e também se descartou a presença de serino-peptidases, cisteíno-peptidases e enzima conversora da angiotensina I. A maior atividade enzimática do extrato citosólico sobre os outros preparados (membrana/parede celular ou lisado total das leveduras) pode indicar uma localização citosólica dessa enzima. Não foi observada a secreção da peptidase no sobrenadante de cultura in vitro, mesmo após adição de soro fetal bovino. Todavia, a peptidase com atividade TOP-like de Pb parece ser secretada in vivo, ou liberada após lise do fungo por componentes efetores da resposta imune, uma vez que anticorpos capazes de inibir a atividade peptidásica são encontrados em soros de pacientes com paracoccidioidomicose, e soros com maior título em imunodifusão contém maiores concentrações de anticorpos enzima-específicos. Várias enzimas da família M3 clivam bradicinina, importante mediador inflamatório in vivo. A hidrólise da bradicinina e do substrato Abz-GFSPFRQEDDnp pelo extrato citosólico de P. brasiliensis, gera os mesmos fragmentos observados após clivagem pela TOP de mamíferos, que são diferentes dos gerados pela clivagem com MIP de mamíferos e OpdA bacteriana, sendo mais um indicador da presença majoritária de uma peptidase com atividade TOP-like em P. brasiliensis. A clivagem da bradicinina pela metalooligopeptidase com atividade TOP-like de Pb, poderia ocorrer no sítio inflamatório e poderia estar envolvida na inibição da indução de uma resposta imune protetora contra o fungo, favorecendo a permanência do mesmo no hospedeiro. Observamos ainda que o gene homólogo de TOP em P. brasiliensis é quase duas vezes mais expresso no virulento em comparação ao não virulento. O aumento da hidrólise do substrato Abz-GFSPFRQ-EDDnp também foi observado no isolado de maior virulência quando comparado ao de menor virulência. A possível relação entre a expressão da metalooligopeptidase com a virulência do fungo sugere que essa peptidase possa ser classificada como um fator de virulência fúngica, no entanto experimentos complementares são necessários para sua confirmação. A expressão da gp43 também foi analisada no isolado virulento e não virulento e observou-se uma expressão aumentada em até treze vezes no primeiro. Para melhor caracterização dessas metalo-oligopeptidases é necessária a obtenção da proteína recombinante, ou da proteína purificada nativa, isolada do lisado fúngico. Não obtivemos sucesso na expressão das proteínas recombinantes, tampouco no isolamento da peptidase nativa por métodos cromatográficos. Nossos resultados sugerem a presença de uma atividade metalooligopeptidásica TOP-like na fração citosólica de leveduras de P. brasiliensis. Liberação in vivo dessa enzima após a lise de fungos ou secreção estimulada por fatores do hospedeiro, pode ter um papel na inflamação e desenvolvimento da micose.
Paracoccidioidomycosis (PCM), caused by the pathogenic fungus Paracoccidioides brasiliensis (Pb) is a systemic mycosis with severe acute and chronic forms. Proteases or peptidases are proteolytic enzymes that occur in all organisms and constitute 1-5% of their genetic contents. These enzymes are involved in biological processes such as blood clotting, cell death and tissue differentiation. Several important proteolytic steps occur during the invasion of metastatic tumors, as well as in the infection of a large number of viruses and pathogens. To date, a small number of Pb proteases were isolated and characterized, also, their activities during the development of the disease was not determined, and an oligopeptidase activity was not detected in this fungus. In the present work, we demonstrated a metallopeptidase thimet oligopeptidase (TOP)-like activity in the cytosolic extract of Pb18 yeasts. Our results shown a major hydrolysis of the fluorescence resonance energy transfer (FRET) peptide Abz-GFSPFRQ-EDDnp, preferentially cleaved by TOP from mammals, and the inhibition of the hydrolysis of this peptide by orthophenantrolin and JA-2, selective inhibitors of metalloproteases and TOP, respectively. The presence of neurolysin- like and neprilysin-like, serinepeptidases, cysteine-peptidases and angiotensin converting enzyme I was discarded by analyzing selective FRET peptides and inhibitors. The higher peptidase activity of cytosolic extracts over the membrane/cell wall and total yeast lysate preparations may indicate that this enzyme is localized in the yeast cytosol. The metallo-oligopeptidase activity was not detected on in vitro culture supernatants, even after addition of fetal calf serum. However, the peptidase with TOP-like activity of P. brasiliensis seems to be secreted in vivo, or released after fungal lysis by immune factors, since antibodies that can inhibit this enzymatic activity were found in sera from paracoccidioidomycosis patients, and serum with highest titer in immunodiffusion contains higher concentrations of enzymespecific antibodies. Bradykinin, an important inflammatory mediator in vivo, is cleaved by several enzymes from the M3 family. The same fragments observed after hydrolysis by TOP were observed after cytosolic extract hydrolysis of bradykinin and the substrate Abz-GFSPFRQ-EDDnp. MIP and bacterial OpdA hydrolysis of these peptides generate different fragments, and this is an additional indicator of a major TOP-like activity in P. brasiliensis yeast cells Bradykinin hydrolysis by the TOP-like metallopeptidase of P. brasiliensis may occur in inflammatory processes and this suggests that the enzyme may be involved in the inhibition of a protective anti-fungal response induction, limiting fungal elimination. We also observed that the expression of the TOP homologous gene in P. brasiliensis has almost a two-fold increased in the virulent isolate 18 compared to the non-virulent isolate. Increased hydrolysis of the substrate Abz-GFSPFRQ-EDDnp was also observed in the most virulent isolate compared to the non-virulent. The possible correlation between TOP-like peptidase expression and fungal virulence suggests that this peptidase could be classified as a fungal virulence factor, however, additional experiments are needed to confirm this hypothesis. Gp43 expression was also analyzed in both isolates, and it was observed a thirteen-fold increase in the expression on the virulent isolate. In order to better characterize the P. brasiliensis TOP-like activity, we attempted to obtain the purified recombinant or the native protein, isolated from fungal lysate. However, we were not successful in the expression of recombinant proteins and neither on the isolation of the native protein using chromatographic methods. Our results suggest the presence of a TOP-like activity in the cytosolic fraction of P. brasiliensis yeasts. In vivo release of this enzyme after fungal lysis, or host factors-stimulated secretion, may have a role in inflammation and development of the disease.
TEDE
BV UNIFESP: Teses e dissertações
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Wagner, Jonathan Mark. "STRUCTURAL BASIS OF SUBSTRATE RECOGNITION IN THIMET OLIGOPEPTIDASE AND DEVELOPMENT OF NANOPARTICLES FOR THERAPEUTIC ENZYME DELIVERY." UKnowledge, 2012. http://uknowledge.uky.edu/biochem_etds/6.
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Neuropeptidases are responsible for degradation of signaling peptides in the central nervous system and periphery. Some neuropeptidases have also been shown to play a role as part of the cell’s hydrolytic machinery responsible for breaking down proteins and peptides into amino acids, and these enzymes therefore influence small peptide availability for antigen presentation. A better understanding of how neuropeptidases recognize their substrates could lead to therapeutics that modulate the activity of these important enzymes. Alternatively, re-engineering these enzymes to selectively hydrolyze undesirable peptides could make them attractive as therapeutics themselves. A key question in understanding the activity of these enzymes is how they are able to recognize a variety of seemingly unrelated amino acid sequences as cleavage sites. We are investigating the basis for this general substrate recognition in neuropeptidases using thimet oligopeptidase (TOP) as a model. Crystal structures of TOP in complex with a variety of substrates and inhibitors shed light on the mechanisms underlying substrate recognition and pave the way for re-targeting substrate recognition in these enzymes.
Nano test tube particles have been proposed as a means of delivering therapeutics such as enzymes. However, the template synthesis method for nano test tube production does not produce therapeutic quantities. In order to take full advantage of re-engineered neuropeptidases a new method for nano test tube synthesis has been developed. We show that a non-destructive template synthesis methodology can be applied to produce nano test tube particles in quantities useful for therapeutic enzyme immobilization.
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BOUDJENNAH, LAZIZ. "Proteolyse des matrices extracellulaires associee a l'invasion tumorale : caracterisation et isolement d'une nouvelle activite gelatinase de type thimet issue du domaine liant la gelatine de la fibronectine." Paris 6, 1998. http://www.theses.fr/1998PA066424.
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La formation des metastases cancereuses implique une surexpression de proteases provoquant la digestion des matrices extracellulaires. La surexpression des genes des principaux types de proteases est maintenant bien etablie dans de nombreux cancers humains. Des fragments de fibronectine provenant de la proteolyse menagee d'une matrice extracellulaire modele par une cysteine-protease sont purifies par quatre chromatographies d'affinites. Ces fragments presentent une activite collagenase/gelatinase apres maturation dans des conditions particulieres. Cette activite a ete etudiee par zymographie et au moyen de substrats specifiques des mmps (metalloproteases matricielles impliquees dans la digestion des collagenes). Une etude avec des inhibiteurs a permis de classer cette nouvelle enzyme comme une metalloprotease zinc-dependante n'appartenant pas a la famille des mmps. Cette protease appartient a la famille des thiol-metalloproteases (thimet). Cette activite serait impliquee dans les mecanismes de migration cellulaire (embryogenese, formation des metastases).
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Waldréus, Nana. "Thirst in Patients with Heart Failure : Description of thirst dimensions and associated factors with thirst." Doctoral thesis, Linköpings universitet, Hälsa, Aktivitet, Vård (HAV), 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-126151.
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Introduction: Nurses and other health care professionals meet patients with heart failure (HF) who report they are thirsty. Thirst is described by the patients as a concern, and it is distressing. Currently there are no standardized procedures to identify patients with increased thirst or to help a patient to manage troublesome thirst and research in the area of thirst is scarce. In order to prevent and relieve troublesome thirst more knowledge is needed on how thirst is experienced and what factors cause increased thirst. Aim: The aim of this thesis was to describe the thirst experience of patients with HF and describe the relationship of thirst with physiologic, psychologic and situational factors. The goal was to contribute to the improvement of the care by identifying needs and possible approaches to prevent and relieve thirst in patients with HF. Methods: The studies in this thesis used a cross-sectional design (Study I) and prospective observational designs (II-IV). Studies include data from patients with HF who were admitted to the emergency department for deterioration in HF (I, IV) or visited an outpatient HF clinic for worsening of HF symptoms (III); others were patients who were following up after HF hospitalization (II), and patients with no HF diagnosis who sought care at the emergency department for other illness (I). Patients completed questionnaires on thirst intensity, thirst distress, HF self-care behaviour, feeling depressive and feeling anxious. Data on sociodemographic, clinical characteristics, pharmacological treatment and prescribed fluid restriction were retrieved from hospital medical records and by asking the patients. Data were also collected from blood, urine and saliva samples to measure biological markers of dehydration, HF severity and stress. Results: Thirst was prevalent in 1 out of 5 patients (II) and 63% of patients with worsening of HF symptoms experienced moderate to severe thirst distress at hospital admission (IV). Patients at an outpatient HF clinic who reported thirst at the first visit were more often thirsty at the follow-up visits compared to patients who did not report thirst at the first visit (II). Thirst intensity was significantly higher in patients hospitalized with decompensated HF compared to patients with no HF (median 75 vs. 25 mm, visual analogue scale [VAS] 0-100 mm; P < 0.001) (I). During optimization of pharmacological treatment of HF, thirst intensity increased in 67% of the patients. Thirst intensity increased significantly more in patients in the high thirst intensity group compared to patients in the low thirst intensity group (median +18 mm vs. -3 mm; P < 0.001) (III). Patients who were admitted to the hospital with high thirst distress continued to have high thirst distress over time (IV). A large number of patients were bothered by thirst and feeling dry in the mouth when they were thirsty (III, IV). Patients with a fluid restriction had high thirst distress over time and patients who were feeling depressed had high thirst intensity over time (IV). Thirst was associated with fluid restriction (III-IV), a higher serum urea (IIIII), and depressive symptoms (II). Conclusions: A considerable amount of patients with HF experiences thirst intensity and thirst distress. Patients who reported thirst at the first follow-up more often had thirst at the subsequent follow-ups. The most important factors related to thirst intensity or thirst distress were a fluid restriction, a higher plasma urea, and depressive symptoms. Nurses should ask patients with HF if they are thirsty and measure the thirst intensity and thirst distress, and ask if thirst is bothering them. Each patient should be critically evaluated if a fluid restriction really is needed, if the patient might be dehydrated or needs to be treated for depression.
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Baird, Katlyn Marie. "Thicket." Kent State University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=kent1619442995285422.
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Kauppi, Erika Donnelly. "A Thirst for More." PDXScholar, 2014. https://pdxscholar.library.pdx.edu/open_access_etds/1652.
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A Thirst for Moretakes the reader on a journey into self-development culture around Portland, Oregon. The author attends events devoted to personal growth to try to understand how this culture shapes our lives and the way we think. Along the way, she encounters psychics, mystics, an alleged cult leader, and seekers and self-reinventors of all stripes. As participants in this culture work to build their own philosophies and define their own spirituality, they also create their own communities--intentionally and otherwise. These communities form the heart of this exploration. Chapters 1 and 2 explore the spontaneous communities that arise during afternoon events in which participants pay for goods, services, and information pertaining to personal growth and spirituality. Chapter 3 delves into a sacred art and music festival in which participants gather outdoors for a handful of days in the hopes of connecting with each other and transforming themselves--and society--in the process. The final chapters explore the lives of two communities. In Chapter 4, a woman devotes her life to starting up an eco-village in the foothills of Mt. Hood. In Chapter 5, the author visits a 41-year-old commune in which residents and visitors have abandoned former lives in their search for meaning, fulfillment, belonging, and a place to call home.
As the author questions others about their beliefs, she begins to question her own. Why do we believe what we believe?
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Gournay, Dominique. "Thibet de Victor Segalen : itinéraire d'une esthétique a une poétique." Paris 10, 1995. http://www.theses.fr/1995PA100164.
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Pour mieux cerner la nature de Thibet, la dernière œuvre écrite par Victor Segalen, la première partie de la thèse expose quelques aspects majeurs de son esthétique. L'essai sur l'exotisme fournit des repères théoriques. Les écrits de Segalen consacrés a la musique, à la peinture et à la sculpture montrent la spécificité de chaque art et le statut dévolu tant à l'artiste qu'a ses œuvres. Le double Rimbaud, peintures, équipée éclairent les ambitions et les limites de la création poétique. Thibet se trouve ainsi place dans le cadre d'une quête esthétique et ontologique. La deuxième partie s'arrête sur les éléments propres a constituer la poétique de Thibet. Malgré les incertitudes liées a l'inachèvement du poème, la cohérence de l'œuvre apparait dans la succession des séquences comme dans la récurrence des thèmes. Un Tibet originel s'y trouve érigé en symbole; il est l'objet du poème qui cherche paradoxalement à atteindre le divers et l'autre inaccessibles. Segalen organise puissamment son chant poétique en usant des multiples ressources de la métrique, du rythme et des effets sonores. Des références littéraires et liturgiques contribuent à éclairer les principes de la composition du poèmeThis dissertation attempts to assess the specificity of Thibet, Segalen's last poem. The first part of the dissertation deals with some of the major aspects of Segalen's aesthetics. The Essai sur l'exotisme furnishes theoretical data. Besides Segalen's writings on music, painting and sculpture confirm the poet's belief in the originality of artistic achievements and the particular status of the artist and his work. Double Rimbaud, painters equipped expound the aims and set the limits of poetic creation. Thibet thus appears as the ultimate aesthetic and ontological quest. The second part of the dissertation analyses the components of poetry in Thibet. Despite uncertainties due to the fact that the poem is unfinished, Thibet has a coherence of its own thanks to the succession of sequences and recurring themes. A kind of primeval Thibet is thus turned into a symbol. The poem then becomes an attempt to capture multiplicity and otherness. Segalen builds up a powerful poetic song, making use of all the devices of prosody, rhythm and sound-effects. Literary and liturgical references help to understand the underlying rules of poetic composition
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Bennett, Reuel Matignas [Verfasser], Marco [Akademischer Betreuer] Thines, and Marco [Gutachter] Thines. "Phylogeny of mangrove oomycetes / Reuel Matignas Bennett ; Gutachter: Marco Thines ; Betreuer: Marco Thines." Frankfurt am Main : Universitätsbibliothek Johann Christian Senckenberg, 2021. http://d-nb.info/1236376897/34.
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Thiel, Karsten. "Strukturelle Untersuchung der amorph-kristallinen Grenzfläche mittels quantitativer hochauflösender Transmissionselektronenmikroskopie an den Systemen a-Si-c-Si und a-Ge-c-Si." [S.l.] : [s.n.], 2006. http://webdoc.sub.gwdg.de/diss/2006/thiel.
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Khoza, Thembile Tracy. "The abundance and species richness of the spiders (Araneae : Arachnida) associated with a rivine and sweet thorn thicket, rocky outcrop and Aloe Marlothii thicket in the Polokwane Nature Reserve, Limpopo Province." Thesis, University of Limpopo (Turfloop Campus), 2008. http://hdl.handle.net/10386/923.
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Ralf, Frauke Gisela. "Thieme Open - Your OA-companion." Universitätsbibliothek Chemnitz, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-187569.
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Die Thieme Verlagsgruppe baut Open Access als einen zusätzlichen Publikations-und Autorenservice neben dem vorhandenen breiten Angebot von Veröffentlichungen und Serviceleistungen im Bereich der Medizin, Pflege und Chemie aus. Unser Augenmerk liegt dabei immer auf dem Inhalt und seiner Qualität selbst. Gemeinsam mit unseren Autorinnen und Autoren, Urheberinnen und Urhebern bearbeiten wir diese Inhalte, bis sie eine geeignete Publikationsform angenommen haben. Es sollte jeweils die Form des Inhaltes sein, die den höchsten Einfluß und eine möglichst große Verbreitung des urheberrechtlich geschützten Werkes erlangt. Dieser Ansatz entspricht unserer Leitlinie, einen wirtschaftlich und ökologisch nachhaltigen und qualitativ höchstwertigen Service für alle Interessengruppen aus der Medizin, Pflege und Chemie zu gewährleisten. Open Access ist in diesem Zusammenhang als Teil von Open Science zu sehen, um die Entwicklung von medizinischer Ausbildung, Forschung, Lehre und Pflege zu unterstützen und voranzutreibenThe Thieme Publishing Group fosters Open Access (OA) as an author service in addition to the great variety of existing portfolios, platforms and services we provide. The focus lies on the content itself and together with the authors, we model and shape the form this content should have to create the highest impact. This OA service includes rigorous peer-review, professional in-house editorial services, fast publication times, worldwide access via Thieme\'s electronic journals platform thieme-connect.com, reference linking, marketing, long term archiving, and indexing into PubMed Central and other relevant databases. Our approach is to abide by Thieme\'s overall mission to provide a sustainable, high-quality service to all stakeholders we work with, including especially those who create and use our content
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Phillips, Elizabeth M. G. "Osmoregulation and thirst in cirrhosis." Thesis, University of Newcastle Upon Tyne, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.308018.
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Estes, Bryan. "Thief of Visions." OpenSIUC, 2013. https://opensiuc.lib.siu.edu/theses/1101.
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This thesis is a creative study of poetry and visual art, containing fifty poems and ten illustrations. It is situated on the continuum of a long and rich history of interactions between poetry and the visual arts, from the earliest works of ekphrasis poetry written over two-thousand years ago, and the Haiga poets of 11th-century Japan blending painting and haiku, to the numerous and varied works of contemporary poets and artists. Inspiration for this creative endeavor spans the works of many poet-artists, including William Blake, Mark Strand, Charles Simic, Russell Edson, Anne Carson, Nick Flynn, and Tom Phillips, and many others who have created visual and concrete poetry, erasure poetry, graphic poetry, broadsides, and illustrated collections. The visual art contained in this thesis is not intended as a mere addition to the poetry, rather the poetry and art function as a composite, an integrated form that simultaneously illustrates, augments, contrasts, and distorts.
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L'Ange, Jacqui. "The seed thief." Master's thesis, University of Cape Town, 2012. http://hdl.handle.net/11427/11949.
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Includes abstract.At face value, The Seed Thief is a contemporary quest story. Maddy Bellani, a botanist with the Millennium Seed Bank in Cape Town, is sent on the trail of an African plant thought to be extinct on the continent, and believed to be growing in Brazil.
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Benjamin, Bryan. "Thirst and water in Revelation 21:6 and 22:17." Theological Research Exchange Network (TREN), 1986. http://www.tren.com.
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Thimm, Tatjana. "Kultureller Wandel in Französisch-Polynesien vor dem Hintergrund ausländischer Einflussnahme und endogener Entwicklung Ausgangssituation für nachhaltige Tourismusprojekte der indigenen Bevölkerung der Maohi /." [S.l. : s.n.], 2001. http://webdoc.sub.gwdg.de/diss/2001/thimm/thimm.pdf.
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Bielmeier, Douglass Christopher. "The Thief of Always." Bowling Green State University / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1136924509.
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Grabocka, Josif [Verfasser], Lars [Akademischer Betreuer] [Gutachter] Schmidt-Thieme, and Mustafa [Gutachter] Baydogan. "Invariant Features For Time-Series Classification / Josif Grabocka ; Gutachter: Lars Schmidt-Thieme, Mustafa Baydogan ; Betreuer: Lars Schmidt-Thieme." Hildesheim : Universität Hildesheim, 2016. http://d-nb.info/1126254487/34.
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Grabocka, Josif Verfasser], Lars [Akademischer Betreuer] [Schmidt-Thieme, and Mustafa [Gutachter] Baydogan. "Invariant Features For Time-Series Classification / Josif Grabocka ; Gutachter: Lars Schmidt-Thieme, Mustafa Baydogan ; Betreuer: Lars Schmidt-Thieme." Hildesheim : Universität Hildesheim, 2016. http://d-nb.info/1126254487/34.
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Argent, Nicholas B. "Thirst and vasopressin in chronic renal failure." Thesis, University of Bristol, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.281865.
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Thiel, Kilian [Verfasser]. "Knotenähnlichkeiten aus Aktivierungsausbreitungen / Kilian Thiel." Konstanz : Bibliothek der Universität Konstanz, 2012. http://d-nb.info/1020794275/34.
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Thiel, Alexander [Verfasser]. "Artikel und Abstrakta / Alexander Thiel." Wuppertal : Universitätsbibliothek Wuppertal, 2017. http://d-nb.info/1131275969/34.
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Dubau, Gerold. "Thimo von Colditz und Stolpen." Sandstein Verlag, 2005. https://slub.qucosa.de/id/qucosa%3A38370.
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In 340 Jahren regierten 24 Meißner Bischöfe über das Land und Amt Stolpen. Einige wählten die Burg sogar zu ihrem Hauptaufenthaltsort einschließlich umfangreicher Hofhaltung. Bischof Thimo von Colditz gehörte zu den herausragenden Bischöfen sowohl als Bauherr als auch Streitbarer im fortwährenden Kampf gegen die Ansprüche der wettinischen Markgrafen.
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Trisos, Christopher. "Potential key drivers of thicket expansion in savanna." Bachelor's thesis, University of Cape Town, 2007. http://hdl.handle.net/11427/26301.
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The invasion of grasslands by woody plants and their increase in savannas is a global phenomenon. There has been a lot of work on the ecology of savanna trees, but very little on the drivers of the increase of non-savanna (forest and thicket) vegetation within savannas. The swit9h from savanna to closed canopy thicket represents a biome switch for the system and is therefore of concern to land and conservation managers. Data on height growth, root suckering and fire damage were collected for two thicket forming species. A simulation model was developed to evaluate the effect of different biotic and abiotic factors on the spread of a thickerclump in savanna in the Hluhluwe Game Reserve, South Africa. The amount of damage from fire suffered by a thicket clump is increased by higher fire intensity and decreased by larger clump area or greater pre-burn mean clump height. A sensitivity analysis indicated that increased height and area growth rates and decreased fire frequency allows thicket expansion to occur and that data on these is essential for predicting the expansion of thicket clumps. Predictions from the model suggest that a thicket clump's situation within the landscape is important and that spatial modelling, incorporating fire spread and fire refugia such as river banks is necessary to further improve understanding of thicket expansion.
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Landman, Marietjie. "Megaherbivores in succulent thicket: resource use and implications." Thesis, Nelson Mandela Metropolitan University, 2012. http://hdl.handle.net/10948/d1007956.
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This study aims to develop a predictive understanding of the resource use, impacts and interactions of elephant Loxodonta africana and black rhinoceros Diceros bicornis in the succulent thickets of the Eastern Cape, South Africa. While these megaherbivores typically dominate the biomass, elephant are more abundant, such that their impacts off-set that of all other herbivores. Consequently, this thesis has three main foci: first, developing a mechanistic understanding of the influences of elephant; second, developing predictive insights into elephant impacts on plant communities; finally, an understanding of the knockon-effects of the impacts for coexisting rhinoceros. Thus, by documenting the diet and dietary preferences of elephant, I firstly show that only about 18 percent of the species previously thought vulnerable to herbivory, occur in the diet. This refutes the generally held belief that elephant herbivory is the primary driver of decline among plants, and emphasizes the likely contribution of other mechanisms (e.g. trampling, knock-on-effects, etc.). Thus, the accurate prediction of the impacts caused by elephant requires an understanding of previously marginalized mechanisms. From here, I quantify >50 years of impacts on the thicket shrub community and test their spatial and temporal extent near water. I confirm the vulnerability of thicket to transformation (particularly near water) as the accumulated influences of elephant reduce community composition and structure, and predict that these impacts will eventually bring about landscape-level degradation and a significant loss of biodiversity. Importantly, results show an uneven distribution of effects between elements of this community: from community composition and structure, to the structure of individual canopy species and ecological functioning. While these findings confound our interpretation of the extent of the impacts, it demonstrates the importance of explicitly recognizing biodiversity and heterogeneity for the conservation management of elephant. Finally, I test the consequences of the impacts for coexisting rhinoceros. While I show that this causes rhinoceros to change their foraging strategies in the presence of elephant at high densities, I also show that elephant may facilitate access to food for rhinoceros at reduced densities. These findings indicate the importance of elephant in driving the structure and composition of the thicket shrub community and the consequences of this for coexisting large herbivores. Thus, developing a predictive understanding of the spatial and temporal variations of elephant impacts between elements of biodiversity and the mechanisms driving these changes are key to their management. This implies that the effective conservation management of elephant can only be achieved through the careful, scientific design of monitoring programmes.
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Yu-Hong, Li, Nana Waldréus, Joachim Zdolsek, and Robert G. Hahn. "Effects of tap water, electrolyte solution, and spontaneous and furosemide-stimulated urinary excretion on thirst." Linköpings universitet, Anestesiologi med intensivvård, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-85178.
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AIM: To contrast the effects of various modifications of body fluid volumes on thirst as reported by healthy volunteers. METHODS: Ten male volunteers aged between 19 and 37 years (mean 22 years) underwent four experiments each, which comprised infusion of 400-800 mL of acetated Ringer’s solution and intake of 600 mL of tap water. Half of the experiments were preceded by volume depletion (median 1.7 L) with furosemide. A visual analogue scale (0-100 mm) was used to assess perceived thirst during each experiment. RESULTS: Volume depletion (P < 0.001) and tap water (P < 0.03) both affected thirst by 13 mm per L of fluid, whereas spontaneous diuresis and infusion of Ringer’s acetate did not significantly change the thirst rating (multiple regressions). More detailed analyses showed that the volume depletion increased the median (25th-75th percentiles) thirst rating from 28 mm (21-43) to 59 mm (46-72, P < 0.001) while no change occurred in those who were only slightly thirsty (< 30 mm) before the volume depletion began. Ringer’s solution alleviated thirst in those who were very thirsty, but tended to increase thirst in the volunteers who were not thirsty before the infusion. Similarly, hydration with tap water decreased thirst (by 24 mm, P < 0.04) in those who were thirsty (> 60 mm) while the others reported no change. CONCLUSION: The change in thirst rating during volume depletion, administration of Ringer’s acetate, and ingestion of tap water were all dependent on the thirst rating obtained when the manipulation of the body fluid volume was initiated.
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Schatten, Carlotta Verfasser], Lars [Akademischer Betreuer] [Gutachter] Schmidt-Thieme, and Niels [Gutachter] [Pinkwart. "Sequencing in Intelligent Tutoring Systems based on online learning Recommenders / Carlotta Schatten ; Gutachter: Lars Schmidt-Thieme, Niels Pinkwart ; Betreuer: Lars Schmidt-Thieme." Hildesheim : Universität Hildesheim, 2017. http://d-nb.info/113911798X/34.
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Schatten, Carlotta Verfasser], Lars [Akademischer Betreuer] [Schmidt-Thieme, and Niels [Gutachter] Pinkwart. "Sequencing in Intelligent Tutoring Systems based on online learning Recommenders / Carlotta Schatten ; Gutachter: Lars Schmidt-Thieme, Niels Pinkwart ; Betreuer: Lars Schmidt-Thieme." Hildesheim : Universität Hildesheim, 2017. http://d-nb.info/113911798X/34.
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Potts, Alastair John. "Tracking thicket through space and time : insights into the evolutionary history of the Albany Subtropical Thicket from comparative phylogeography and distribution modelling." Doctoral thesis, University of Cape Town, 2011. http://hdl.handle.net/11427/12174.
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Includes abstract.Includes bibliographical references (leaves 191-219).
Albany Subtropical Thicket (AST) is a species-rich biome restricted to the coastal lowlands of the southern Cape region of South Africa. Its Quaternary history is poorly understood, but climatic changes associated with Pleistocene glacial cycles may have profoundly affected the distributions, gene flows, and demographies of species. The glacial refugia hypothesis predicts that AST retracted into fragmented refugia during glacial cycles. The evolutionarily discrete drainage basin (EDDB) hypothesis suggests that the prevailing topography played an important population-structuring role. I evaluate these two hypotheses by combining community and species distribution models with multigene comparative phylogeography of three AST species Pappea capensis, Nymania capensis, and Schotia afra. Distribution models support the glacial refugia hypothesis, with highly reduced and fragmented distributions postdicted for the Last Glacial Maximum. These models, projected onto two climate scenarios for 2050, give a positive outlook for the future of AST, with no dramatic shifts or reduction in appropriate climate...
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La, Cock Graeme Dennis. "The conservation status of subtropical transitional thicket, and regeneration through seeding of shrubs in the Xeric succulent thicket of the Eastern Cape." Thesis, Rhodes University, 1992. http://hdl.handle.net/10962/d1003777.
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The historically poorly conserved subtropical transitional thicket (STT) of the Eastern Cape is overutilised by domestic stock and game in the more xeric areas, and has shown no signs of recovery from this grazing pressure. It has been postulated that no regeneration through seeding occurs. This project was undertaken to determine: 1) how much STT has disappeared between 1950 and present, and what the current conservation status is; and 2) whether regeneration of the xeric succulent thicket is taking place through seeding, and if so, where. The study was conducted at the Andries Vosloo Kudu Reserve near Grahamstown. Approximately one-third less STT was mapped in this study, based on 1981 Landsat images, than was mapped in 1950. Approximately 10 % of all remaining STT is conserved. The order Kaffrarian thicket is poorly conserved. Newly germinated seedlings of a wide range of shrub species occurred under the canopies of a wide range of shrubs which served as nurse plants, throughout a gradient of veld condition. Seedlings of Portulacaria afra, the dominant shrub in xeric succulent thicket, were most common. Similarly all saplings recorded in a survey of saplings were associated with bushclumps. One-third of all saplings have the potential to contribute to the spread of bushclumps. Regeneration of xeric succulent thicket through seeding probably does occur, contrary to current ideas. Ptareoxylon obliquum was the most common sapling, despite mature trees now being scarce following earlier heavier utilisation . P. obliquum was also the nurse plant which supported the highest density of newly germinated seedlings. The possible role of P. obliquum in the functioning of xeric succulent thicket is discussed. The confinement of seedlings and saplings to areas under the canopies of trees and shrubs implies that the xeric succulent thicket will not recover rapidly if allowed to rest. Active management techniques will be necessary if rapid recovery is required. Bare areas between bushclumps may no longer be suitable germination habitats because of high Al concentrations. There was no evidence to support the idea that germination and establishment of shrubs in clear areas is linked to episodic climatic events. Dung middens of recently reintroduced black rhinoceros may however aid in germination of seeds and establishment of seedlings under certain climatic conditions. Recommendations for further studies, based on the findings of this project, are made. Possible management techniques aimed at the rapid recovery of this veld are suggested, and management proposals for the Sam Knott Nature Reserve/Andries Vosloo Kudu Reserve complex are made.
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Schmidt, Johnna Marie. "The Book thief and other stories." College Park, Md. : University of Maryland, 2004. http://hdl.handle.net/1903/1529.
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Thesis (M.F.A.) -- University of Maryland, College Park, 2004.Thesis research directed by: Dept. of English. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
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Thieme, Louise [Verfasser]. "Klinische und funktionelle Langzeitergebnisse von behandelten Klumpfüßen / Louise Thieme." Lübeck : Zentrale Hochschulbibliothek Lübeck, 2014. http://d-nb.info/1046429604/34.
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Schönfuß-Krause, Renate. "J. F. Balthasar Thieme: (1751 - 1841), Bürgermeister und Chronist." Teamwork Schönfuß, 2021. https://slub.qucosa.de/id/qucosa%3A73731.
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Johann Balthasar Thieme (* 28. Dez. 1751 in Großdittmannsdorf, † Juni 1841 in Radeberg), Bürgermeister von Radeberg 1799 - 1806, hoch angesehener Bürger und Kaufmann. Sein besonderes Verdienst besteht als Historiker, Chronist mit der ersten Autorenschaft der „Radeberger Chronik Thieme - Knobloch“, die er ins Leben rief und mit der er alle in Radeberg und seiner Umgebung auftretende Besonderheiten und Vorkommnisse festschrieb, eine Primärchronik von unschätzbarem Wert.
Thiemes Credo als Bürgermeister: „Ums Wohl der Stadt muss man sich treu bemühen. Sein Wunsch war: Möge Radeberg stets blühen“
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Buaya, Anthony Tumenez [Verfasser], Marco [Akademischer Betreuer] Thines, Marco [Gutachter] Thines, Gordon [Gutachter] Beakes, Helge [Gutachter] Bode, and Claus [Gutachter] Bässler. "The simple holocarpic oomycetes: Taxonomy and phylogenetic study / Anthony Tumenez Buaya ; Gutachter: Marco Thines, Gordon Beakes, Helge Bode, Claus Bässler ; Betreuer: Marco Thines." Frankfurt am Main : Universitätsbibliothek Johann Christian Senckenberg, 2020. http://d-nb.info/1215756194/34.
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Knoll, Karen [Verfasser], and Hans-Thies [Akademischer Betreuer] [Gutachter] Lehmann. "Unordnung im Sinnlichen : zum politischen Theater René Polleschs / Karen Knoll. Betreuer: Hans-Thies Lehmann. Gutachter: Hans-Thies Lehmann." Frankfurt am Main : Universitätsbibliothek Johann Christian Senckenberg, 2013. http://d-nb.info/1107182824/34.
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Semones, Shawn Wayne. "Inhibition of Canopy Tree Seedlings by Thickets of Rhododendron maximum L. (Ericaceae) in an Eastern Deciduous Forest." Diss., Virginia Tech, 1999. http://hdl.handle.net/10919/29688.
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Rhododendron maximum L. (Ericaceae) is an evergreen shrub that grows in dense thickets and currently covers large areas of the understory in the deciduous forests of the southeastern United States. Thickets of R. maximum are inhibitory to recruitment and regeneration of many understory plants including canopy tree seedlings. By effectively lowering the survivorship of woody species trying to establish within thickets, R. maximum could influence stand level regeneration patterns and ultimately the community structure of these deciduous forests. This dissertation outlines research conducted to determine if: 1) below and above ground resources are lower within thickets of R. maximum when compared to forest sites where R. maximum is absent; 2) Quercus rubra and Prunus serotina seedlings growing in thickets have lower mid-day photosynthetic rates; 3) Quercus rubra and Prunus serotina seedlings growing within thickets are low light acclimated when compared to seedlings growing in forest without R. maximum; 4) the presence of R. maximum constrains CO₂ assimilation of Quercus rubra seedlings exposed to light flecks of different durations and intensities; 5) the presence of R. maximum constrains the light fleck responses of Quercus rubra seedlings exposed to eight light flecks in rapid succession; and 6) canopy openness regulates the capacity of Quercus rubra seedlings to assimilate carbon when exposed to eight consecutive light flecks.
Rhododendron maximum thickets altered resource availability for seedlings when compared to areas of forest without R. maximum. Diffused photosynthetically active radiation (PAR) averaged less than 5 μmol m⁻² s⁻¹ throughout the growing season in sites with R. maximum in comparison to 10-30 μmol m⁻² s⁻¹ in sites without R. maximum. Soil moisture content, measured using Time Domain Reflectometry was approximately 6% lower in forest sites with R. maximum compared to sites without R. maximum throughout the growing season. Most nutrient concentrations (e.g.,, C, N and most cations) and nitrogen mineralization rates were significantly lower in sites with R. maximum. Temperature and atmospheric relative humidity are slightly lower under thickets of R. maximum. In general, sites with R. maximum are associated with lower resource availability above and below ground in comparison with sites without R. maximum.
Attenuation of below canopy PAR by thickets of R. maximum negatively influences the photosynthetic capacity of Quercus rubra and Prunus serotina seedlings as indicated by measurements of mid-day photosynthesis. In 1996, the seasonal mean mid-day photosynthetic rate of first year Q. rubra seedlings growing in R. maximum thickets (1.3 μmol m⁻² s⁻¹) was 62% lower than the seasonal mean mid-day photosynthetic rate (2.1 μmol m⁻² s⁻¹) of seedlings growing in forest sites without R. maximum. For second year seedlings in 1997, seasonal mean mid-day photosynthesis was 183% higher for plants growing outside of thickets (1.7 μmol m⁻² s⁻¹) compared to the mean rate (0.6 μmol m⁻² s⁻¹) for plants located within thicket sites. The mean mid-day PAR available to seedlings located in forest sites without R. maximum during measurements of photosynthesis was 354% higher in 1996 and 257% higher in 1997. First year Prunus serotina seedlings growing in forest without R. maximum also had greater seasonal mean mid-day photosynthesis (0.7 μmol m⁻² s⁻¹) when compared to the mean rate (-0.1 μmol m⁻² s⁻¹) for plants growing within thickets. Prunus serotina seedlings located in the presence of R. maximum received on average 67% less PAR.
Photosynthetic acclimation to low light was assessed for Q. rubra and P. serotina seedlings growing under both forest conditions by measuring photosynthetic responses to light in situ using even aged one-year old seedlings. Quercus rubra seedlings growing in forest sites without R. maximum had significantly higher light saturated rates of photosynthesis. For both species, photosynthetic responses to light were otherwise similar irrespective of the presence or absence of R. maximum.
The impact of the R. maximum subcanopy on understory PAR and subsequent influence on canopy tree seedling photosynthetic capacity implies that sunflecks are critical for seedling net carbon gain in these forest understory environments. To determine the effect of R. maximum on the photosynthetic response to sunflecks of oak seedlings, light flecks were simulated on 288 randomly chosen, even aged, two-year old seedlings in situ. Half of the seedlings were located within R. maximum thickets. Seedlings were randomly assigned one of four light fleck durations (30, 60, 120, and 300s) and one of three intensities (100, 500, 1000 μmol m⁻² s⁻¹). Half of all seedlings were dark pre-acclimated prior to light fleck simulations by covering with aluminum foil for at least 12 hours, while the remaining seedlings were pre-acclimated under ambient conditions.
Analysis of covariance showed that a significant, positive, linear relationship exists between the length of a light fleck and total carbon gain during a light fleck for seedlings in forest sites with and without R. maximum regardless of pre-acclimation status, or light fleck intensity. Furthermore, there was a significant effect of R. maximum on the slope of the relationship such that following ambient pre-acclimation, seedlings located within thickets assimilated significantly less carbon with increasing light fleck length than seedlings located in forest sites without R. maximum. When seedlings were dark pre-acclimated there was no difference in carbon gain with increasing fleck length between seedlings in forest with and without R. maximum except for flecks of 1000 μmol m⁻² s⁻¹. The data lead to the conclusion that under natural conditions the presence of R. maximum likely prohibits Q. rubra seedlings from utilizing sunflecks as effectively as seedlings growing in forest sites where R. maximum is absent.
Because sunflecks often occur clustered together during a short period of time during the day, another field study was conducted to further characterize the effect of R. maximum on the photosynthetic response of oak seedlings to eight consecutive light flecks. Within 10 paired sites, (i.e., with and without R. maximum) 3 even aged three-year old Q. rubra seedlings were selected. Over each seedling, a hemispherical canopy photograph was taken and analyzed for percent canopy openness. Each seedling was dark pre-acclimated for 12 hours and then exposed to eight light flecks in rapid succession during which time photosynthesis was logged every two seconds. Each light fleck was 500 μmol m⁻² s⁻¹ in intensity and lasted for 120s. Following each light fleck, leaves were exposed to 10 μmol m⁻² s⁻¹ PAR for 60s before the next light fleck.
Mean carbon gain and maximum photosynthesis achieved during each light fleck was significantly lower for seedlings located in the presence of R. maximum for all flecks in an eight-fleck simulation. In addition, seedlings located within thickets generally had significantly lower pre-illumination photosynthesis following the first of eight light flecks. The mean photosynthetic light use efficiency of seedlings located in forest with R. maximum was significantly lower for the first six of eight light flecks in succession. Using regression analysis and analysis of covariance, percent canopy openness was used to explain the variation in carbon gained from all eight light flecks in succession for seedlings under both forest conditions. However, significant relationships failed to exist between under either forest condition and precluded using analysis of covariance.
The results from these studies lead to the conclusion that light limitation is a major mechanism responsible for the extirpation of canopy tree seedlings from within thickets of R. maximum. Tree seedlings growing in forest sites with R. maximum receive less solar irradiance, have lower mid-day photosynthesis, fail to acclimate to the lower light conditions within thickets, and utilize sunflecks less effectively as well as less efficiently when compared to plants growing in forest sites without R. maximum.Ph. D.
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Thiel, Ulrich [Verfasser]. "On restricted rational Cherednik algebras / Ulrich Thiel." München : Verlag Dr. Hut, 2014. http://d-nb.info/1055863974/34.
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Thiel, Christian [Verfasser]. "Multiple Classifier Systems Incorporating Uncertainty / Christian Thiel." München : Verlag Dr. Hut, 2010. http://d-nb.info/1009095625/34.
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Thies, Thorsten [Verfasser]. "Isoperimetrische Ungleichungen in symmetrischen Räumen / Thorsten Thies." Karlsruhe : KIT-Bibliothek, 2002. http://d-nb.info/1013897099/34.
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Thiel, Lars [Verfasser]. "The Social Context of Health / Lars Thiel." Wuppertal : Universitätsbibliothek Wuppertal, 2017. http://d-nb.info/1124480412/34.
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Thiem, Philipp [Verfasser], and Wolfram [Gutachter] Voelker. "Instant Adipositas / Philipp Thiem. Gutachter: Wolfram Voelker." Würzburg : Universität Würzburg, 2012. http://d-nb.info/1102825824/34.
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Kastel, Thiemo [Verfasser]. "Live Performances and Broadcast Productions with Augmented Reality / Thiemo Kastel." Gernsbach : Prof.(FH) Dr. Thiemo Kastel, kastel media solutions, 2017. http://d-nb.info/1139666266/34.
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Thieme, Günter [Verfasser]. "Regionale Unterschiede der agrarstrukturellen Entwicklung : Untersuchungen im Vorderwesterwald / Günter Thieme." Bonn : Universitäts- und Landesbibliothek Bonn, 2020. http://d-nb.info/1219430773/34.
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Jusoh, Normah. "Hydration, thirst and fluid balance in resting and exercising individuals." Thesis, Loughborough University, 2010. https://dspace.lboro.ac.uk/2134/6641.
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Adequate fluid consumption is central to human survival. Previous literature suggests that there some misconceptions regarding hydration and fluid balance in some populations. Available data also show that the role of thirst sensations in maintaining fluid balance in different settings is also equivocal. Therefore, this thesis aimed to examine the perception of hydration, thirst and fluid intake in freeliving populations, to examine the feasibility of thirst as a marker of hydration status and to investigate the effect of thirst related sensations on fluid balance in resting and exercising individuals under different ambient temperatures. The findings in this thesis (Chapter 3) show that individuals who work within the fitness industry demonstrated substantial knowledge about drinking practices, hydration status and health consequences of water consumption, but lack understanding on the type of beverages that adequately hydrate the body. Further, thirst perception and mood states did not affect (P>0.05) the fluid intake in free living individuals (Chapter 4) and resting individuals under cool and warm exposure (Chapter 6), but some other factors such as subjective feelings of mouth dryness and the extent of hydration status might influence the fluid intake behaviour in these populations. In addition, following ingestion of flavoured carbohydrate drinks, thirst sensations was rated lower over time (P<0.05) during exercise in the cool, but was higher over time in the warm temperature (Chapter 7). Moreover, subjective feelings related to dehydration such as mouth dryness, thirst perception, desire to drink (water pleasantness) and hunger rating could be used as index of hydration status to signify at least a 1% body mass loss due to food and fluid restriction in resting individuals (Chapter 5). In conclusion, the findings in this thesis provide some new insight with respect to hydration, thirst and fluid balance in different populations under different settings. Nevertheless, some inconclusive findings regarding the role of thirst related sensations in fluid balance require further investigations.
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Thieme, Merle Sophie [Verfasser]. "Molekulargenetische Charakterisierung von Patienten mit hypophosphatämischer Rachitis / Merle Sophie Thieme." Lübeck : Zentrale Hochschulbibliothek Lübeck, 2014. http://d-nb.info/1063975425/34.
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Thimmel, Sascha [Verfasser], and Peter [Akademischer Betreuer] Schettgen. "The Market-Orientated Learning Organization / Sascha Thimmel ; Betreuer: Peter Schettgen." Augsburg : Universität Augsburg, 2018. http://d-nb.info/1154386236/34.
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Thimmel, Sascha Andreas [Verfasser], and Peter [Akademischer Betreuer] Schettgen. "The Market-Orientated Learning Organization / Sascha Thimmel ; Betreuer: Peter Schettgen." Augsburg : Universität Augsburg, 2018. http://d-nb.info/1154386236/34.
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