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Journal articles on the topic 'Theraputic'

Author: Grafiati
Published: 4 June 2021
Last updated: 20 February 2023

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1

Murphy, John F. "Theraputic guidelines Ireland." Lasers in Medical Science 4, S1 (March 1989): 359–60. http://dx.doi.org/10.1007/bf02276702.

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2

Kawasaki, Izume, Yoshiaki Shimada, Keisuke Mori, Shin Yoneya, Masayuki Kato, Rajiv Anand, Jorge G. Arroyo, M. Vaughn Emerson, and Christina J. Flaxel. "Diagnostic and Theraputic Challenges." Retina 27, no. 2 (February 2007): 253–58. http://dx.doi.org/10.1097/01.iae.0000243253.52105.54.

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3

Reddy, Shatan, Jason Slakter, Thomas M. Aaberg, Rishi P. Singh, and Peter K. Kaiser. "Diagnostic and Theraputic Challenges." Retina 27, no. 5 (June 2007): 642–47. http://dx.doi.org/10.1097/iae.0b013e31804b4003.

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4

McDonald, Richard. "Diagnostic and Theraputic Challenges." Retina 24, no. 3 (June 2004): 445–49. http://dx.doi.org/10.1097/00006982-200406000-00016.

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5

BELAVADI, DR SANTOSH N., and DR MAMATA Y. KHATAVAKAR. "THERAPUTIC EEFECTS OF AYURVEDA FRUITS." Paryeshana International Journal of Ayurvedic Research 5, no. 4 (July 22, 2020): 1–12. http://dx.doi.org/10.47071/pijar.2020.v05i04.001.

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6

Takagi, Yoshio, Yoshiaki Kumamoto, Naoki Itoh, Akihito Nanbu, Hitoshi Tachiki, Naoto Mikuma, Keigo Akagashi, and Hiroshi Maruta. "THERAPUTIC EVALUATION OF MALE INFERTILITY." Japanese Journal of Urology 81, no. 7 (1990): 1017–24. http://dx.doi.org/10.5980/jpnjurol1989.81.1017.

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7

Thorpe, Cameron, Sven Epple, Benjamin Woods, Afaf H. El-Sagheer, and Tom Brown. "Synthesis and biophysical properties of carbamate-locked nucleic acid (LNA) oligonucleotides with potential antisense applications." Organic & Biomolecular Chemistry 17, no. 21 (2019): 5341–48. http://dx.doi.org/10.1039/c9ob00691e.

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8

Pope, Grahame D. "Theraputic Modalities for Allied Health Professionals." Physiotherapy 85, no. 9 (September 1999): 521. http://dx.doi.org/10.1016/s0031-9406(05)65486-7.

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9

Hassan, Shaimaa, Wafaa Sherif, and Hassanin Hassanin. "ASSESS HEMODIALYSIS PATIENTS COMPLIANCES TO THERAPUTIC REGIMEN." Mansoura Nursing Journal 4, no. 2 (July 1, 2017): 160–70. http://dx.doi.org/10.21608/mnj.2017.149639.

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10

Castro, M. Regina. "Thyroid Nodules—Management Dilemmas and Theraputic Considerations." US Endocrinology 00, no. 01 (2005): 1. http://dx.doi.org/10.17925/use.2005.00.01.1f.

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11

Castro, M. Regina. "Thyroid Nodules - Management Dilemmas and Theraputic Considerations." US Endocrinology 00, no. 01 (2005): 68. http://dx.doi.org/10.17925/use.2005.00.01.68.

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Thyroid nodules are very common in clinical practice, with an overall prevalence that varies from 4% by palpation to 67% by ultrasonography. The annual incidence by palpation has been estimated at 0.09% by the Framingham study,1which translates into approximately 300,000 new nodules in the US in 2005. Despite their high frequency, only a small fraction (~5%) of thyroid nodules harbor cancer. Because only malignant or large, symptomatic nodules will require surgical excision, a systematic approach to their evaluation is important to avoid unnecessary surgery. Certain aspects in the evaluation and management of thyroid nodules remain controversial or represent clinical dilemmas.
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12

Chauhan, K. V., P. N. Kadliya, K. N. Patel, B. A. Patel, and P. A. Patel. "Microbubble: As a Theraputic and Dignostic Tool." International Journal for Pharmaceutical Research Scholars 1, no. 1 (2012): 45–54. http://dx.doi.org/10.31638/ijprs.v1.i1.00020.

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13

Hanoon Jabar, Basim. "Theraputic Plasmapheresis in Neurological Disorders, Baghdad/Iraq." American Journal of Internal Medicine 4, no. 6 (2016): 120. http://dx.doi.org/10.11648/j.ajim.20160406.16.

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14

Guancial, Elizabeth A., Vinay S. Mahajan, Ronald P. McCaffrey, and Neal Lindeman. "Theraputic Monoclonal Antibody Interference In Immunofixation Electrophoresis." Blood 116, no. 21 (November 19, 2010): 4996. http://dx.doi.org/10.1182/blood.v116.21.4996.4996.

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Abstract Abstract 4996 The application of monoclonal antibodies represents an increasingly powerful weapon in the arsenal against hematologic diseases. With the advent of new therapies come previously unrecognized laboratory interference that if not properly identified could have clinical repercussions. We encountered two patients, neither of whom had a history of plasma cell dyscrasia, who underwent treatment with rituximab for immune thrombocytopenic purpura (ITP) and were discovered to have a monoclonal IgG kappa band on serum protein electrophoresis (SPEP) followed by immunofixation (IFX). Both patients had severe, steroid-resistant ITP and received rituximab on an empiric basis, at a weekly dose of 375 mg/m2 IV. In Patient #1, an evaluation for secondary causes of thrombocytopenia included SPEP and IFX. The IFX yielded a faint, atypical IgG kappa band that migrated to the far cathodal zone of the gel. No band was seen on SPEP alone. Since the patient was treated with rituximab the day before these studies were performed, we considered the possibility that the IgG kappa band was due to circulating rituximab. Rituximab is a chimeric antibody composed of human IgG1 kappa chain constant regions and heavy- and light-chain variable regions from a murine anti-CD20 antibody. The elimination half-life of this therapeutic antibody increases with subsequent doses and is approximately 60 hours for the first dose and 174 hours for the fourth dose (range 26 to 442 hours). An aliquot of rituximab was obtained from pharmacy and analyzed by SPEP/IFX, showing an IgG kappa monoclonal protein band identical to the M-protein in the patient's serum. Repeat assessment of serum from this patient obtained immediately prior to her fourth treatment with rituximab demonstrated that the IgG kappa paraprotein was less intense on IFX compared to the first IFX. Several hours after the fourth rituximab infusion was completed, a more intense band corresponding to the IgG kappa paraprotein was detected again on IFX. In Patient #2, who also received rituximab for steroid-resistant ITP, a similar circulating rituximab-related protein was detected on IFX performed one hour after his fourth rituximab infusion. IFX performed on a sample obtained immediately before treatment did not demonstrate a paraprotein, and testing one week after treatment showed that the band had resolved. We believe that awareness of the presence of a faint monoclonal protein by SPEP/IFX following recent administration of rituximab is important to avoid unnecessary further evaluation for a pathologic monoclonal gammopathy. Alternatively, if suspicion exists, SPEP/IFX should be conducted prior to the initiation of treatment with rituximab or after the treatment course is completed in order to avoid uncertainty. Furthermore, it is important to be cognizant of this finding in patients on maintenance rituximab for an indolent lymphoma and an associated paraprotein who may undergo interval monitoring of the monoclonal gammopathy. It is possible that a similar phenomenon may be seen with other therapeutic monoclonal antibodies with a dosing regimen and half-life that is similar to rituximab, such as cetuximab, a monoclonal antibody directed against the epidermal growth factor receptor. Finally, the presence of a characteristic band on immunofixation may allow for the qualitative assessment of the presence of a therapeutic monoclonal antibody in the serum. Further studies are necessary to determine the sensitivity and specificity of such a laboratory test. Disclosures: Off Label Use: Rituximab is an anti-CD20 chimeric antibody and is used for the treatment of immune thrombocytopenic purpura.
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15

Ryazankina, Alla, Aleksey Karelov, Vladimir Glushchenko, S. Rozengard, and M. Rogachev. "THERAPUTIC ALTERNATIVES FOR PHANTOM LIMB PAIN FOLLOWING SURGERY." Problems in oncology 64, no. 1 (January 1, 2018): 126–30. http://dx.doi.org/10.37469/0507-3758-2018-64-1-126-130.

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A study of different analgesic methods for phantom limb pain has been performed in 35 patients who had undergone limb amputation or exarticulation because of oncological disease or vascular disorders. Postoperative analgesia consisted of cyclooxygenese inhibitor and weak opioid. High intensive phantom limb pain appeared in 17 (48.6%) patients that required an administration of pregabalin followed by adenosine triphosphate infusion as analgotesting procedure: it had a success in 9 (52.9%) patients. Remaining 6 patients received nefopam that was effective in 5 of 8 (65.5%) patients. Epidural anesthesia was used with good results in remaining 3 patients. Thus, our data emphasize the complex of phantom limb pain mechanisms and necessity of study for elaboration of medicine effectiveness with different mechanisms of action for such cases.
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16

Murabayashi, Shun. "Current Devices and New Trends in Theraputic Apheresis." Therapeutic Apheresis and Dialysis 7, no. 1 (February 2003): 36. http://dx.doi.org/10.1046/j.1526-0968.2003.00022.x.

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17

Canning, Deebs, John P. Rosenberg, and Patsy Yates. "Theraputic relationships in specialist palliative care nursing practice." International Journal of Palliative Nursing 13, no. 5 (May 2007): 222–29. http://dx.doi.org/10.12968/ijpn.2007.13.5.23492.

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18

IBRAHIM, EISSA ABDEL HAMED, and YASSER AHMED EL SAYED. "DIAGNOSTIC AND THERAPUTIC CHALLENGE IN LIPOMATA AROUND SHOULDER GIRDLE." Journal of the Egyptian Society of Parasitology 50, no. 2 (August 1, 2020): 459–66. http://dx.doi.org/10.21608/jesp.2020.113118.

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19

Farjana, HNilofer, Nithya Anand, and SC Chandrasekaran. "Resolvins: A novel theraputic approach in treating periodontal disease." Indian Journal of Multidisciplinary Dentistry 5, no. 1 (2015): 10. http://dx.doi.org/10.4103/2229-6360.163649.

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20

Dries, D. J. "Theraputic anticoagulation in the trauma patient: Is it safe?" Yearbook of Critical Care Medicine 2010 (January 2010): 308–9. http://dx.doi.org/10.1016/s0734-3299(09)79187-7.

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21

Golob, Joseph F., Mark J. Sando, Justin C. Kan, Charles J. Yowler, Mark A. Malangoni, and Jeffrey A. Claridge. "Theraputic anticoagulation in the trauma patient: Is it safe?" Surgery 144, no. 4 (October 2008): 591–97. http://dx.doi.org/10.1016/j.surg.2008.06.022.

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22

Abdulkareem, Ahmed Hazem, Khulood Majed Alsaraafb, Mustafa Ghazi Alabbassi, and Mustafa Mohammed Al- Obaidy. "Potential Theraputic Effect of Liraglutide in Male Rats Parkinsonn’Disease Model." Al Mustansiriyah Journal of Pharmaceutical Sciences 17, no. 2 (March 9, 2018): 7. http://dx.doi.org/10.32947/ajps.v17i2.39.

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Parkinson’s disease (PD) is a progressive neurodegenerative, chronic disease presented by both nonmotor and motor features. The neuronal loss which rich by dopamine in striatum was the main cause for the PD motor symptoms. While neuronal loss in non-dopaminergic areas support PD nonmotor. liraglutide (Glucagon like peptide-1 mimetic), have effect on CNS by decreasing the number of neutrophils infiltration within CNS which reflect anti-inflammatory characteristics in model of intracerebral haemorrhage in mice. This study represent an attempt o investigate the potential therapeutic effect of liraglutide in male rats Parkinson’s disease model. Thirty six adult male rats were divided into three equal groups. Rats in group A were treated with saline intraperitoneally for 30 days. Meanwhile these rats in group B and group C were treated with 6- hydroxydopamine (6-OHDA) toxicant unilaterally intrathecal injection in a dose of 8 μg/per rat in 2 μl distal water, to introduce Parkinson model in rats. Group B were treated similar to that of group A with saline intraperitoneally for 30 days, while group C were treated with liraglutide intraperitoneally for 30 days in a dose 25nmol/kg. Histological changes were observed by light microscopy. The histopathological study showed that neurotoxins, that is, 6-OHDA, caused marked hypertrophic changes, infiltration of neutrophils, alterations of architecture, and even cell death in group B. Furthermore, many neurons were shrunken, and darkly stained with small nuclei compared with normal vehicle treated rats of group A. There is marked reversal of neuronal damage or neuronal alterations observed with liraglutide (25 nmol/ kg) treated rats in group C.
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23

Gurzhiy, O. V., S. V. Kolomiiets, and O. O. Kulay. "INJURY OF TEMPORARY AND PERMANENT TEETH IN CHILDREN: THERAPUTIC APPROACH." Bulletin of Problems Biology and Medicine 1, no. 4 (2022): 35. http://dx.doi.org/10.29254/2077-4214-2022-4-167-35-43.

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24

Agarwal, Mukta, Bhawana Tiwary, and Prajnanika Gurung. "Complex mullarian duct abnormality in a young female: a theraputic dilemma." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 8 (July 26, 2017): 3673. http://dx.doi.org/10.18203/2320-1770.ijrcog20173510.

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Genital outflow tract obstruction is a rare cause of primary amenorrhoea. Cervical agenesis is a very rare condition often associated with atresia of vagina. Clinical diagnosis is usually difficult before surgery. Transverse vaginal septum or vaginal agenesis is also a rare condition that results from incomplete fusion between vaginal components of the mullerian ducts and urogenital sinus. If the septum is complete, the menstrual flow will be obstructed causing primary amenorrhoea. The septum is basically a membrane of fibrous connective tissue with both muscular and vascular components formed anywhere along the vagina during embryological development. Here we present a case of 18 year old female who presented with primary amenorrhea, cyclical lower abdominal pain and menouria since 5 years. There was no history of attainment of menarche. The clinical examination revealed a small, blind ending lower vagina with a tough transverse membrane separating the lower portion from the upper genital tract. The ultrasound examination revealed a normal size uterus with hematometra. The magnetic resonance imaging of pelvis confirmed the presence of hematometra and transverse vaginal septum. Transverse vaginal septum resection followed by abdomino-perineal cervicoplasty was done in this patient.
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25

Shinkawa, Ryutaro, and Yuhei Nishimura. "Clustering of theraputic drugs using a public database for adverse events." Proceedings for Annual Meeting of The Japanese Pharmacological Society 94 (2021): 2—O—C3–4. http://dx.doi.org/10.1254/jpssuppl.94.0_2-o-c3-4.

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26

Dilling, Daniel F. "Pneumonia Before Antibiotics: Theraputic Evolution and Evaluation in Twentieth Century America." Annals of Internal Medicine 146, no. 11 (June 5, 2007): 828. http://dx.doi.org/10.7326/0003-4819-146-11-200706050-00026.

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27

A. Fathi, Muneeb. "EFFECTS OF THERAPUTIC EXERCISES PROGRAMM FOR REDUCING PAIN OF KNEE OSTEOARTHRITIS." Al-Rafidain Journal For Sport Sciences 19, no. 60 (March 28, 2013): 412–25. http://dx.doi.org/10.33899/rajsport.2013.66741.

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28

AL-Ibraheem, Shrouk A., Nasir A. AL-Mansor, and Kadhim K. AL-Rubaie. "Theraputic and Identifecation Study of Tinea Capitis Infection in Basra City." Indian Journal of Forensic Medicine & Toxicology 13, no. 4 (2019): 1377. http://dx.doi.org/10.5958/0973-9130.2019.00494.8.

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29

Holloway, H., and JF Fielding. "Colonoscopic Findings in Crohn’s Disease - Reproducible, But of Questionable Benefit." Canadian Journal of Gastroenterology 10, no. 6 (1996): 405–12. http://dx.doi.org/10.1155/1996/353967.

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Colonoscopy, a useful diagnostic tool in inflammatory bowel disease, is very accurate in detecting disease and assessing disease extent in Crohn’s disease. Despite their accuracy, colonoscopic findings have not been routinely used in the objective follow-up of patients with Crohn’s disease. The GETAID (Groupe d’études theraputic des affections inflammatoire du tube digestif) group has shown that following an intensive training period, endoscopists can describe colonoscopic findings in a reproducible manner. However, these descriptions poorly correlate both with clinical or laboratory indexes, and with short or medium term prognosis following prednisolone therapy.
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30

SANAD, MAGDA, DALIA ABO EL MAATY, NAGLAA ABD EL-AAL, ASMAA AL-GHANDOUR, AZZA FARAG, ASMAA YOUSEF, and TAHANI FARAG. "THERAPUTIC EFFICACY OF PROBIOTICS AGAINST EXPERIMENTAL GIARDIASIS: HISTOPATHOLOGICAL, HISTOCHEMICAL AND ULTRASTRUCTURAL CHANGES." Journal of the Egyptian Society of Parasitology 50, no. 1 (April 1, 2020): 21–32. http://dx.doi.org/10.21608/jesp.2020.88747.

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31

Liu, Yunguang, and Jingxin Qiu. "Solitary Intracranial Plasmacytoma Located in the Clivus: A Diagnostic and Theraputic Challenge." American Chinese Journal of Medicine and Science 5, no. 4 (2012): 232. http://dx.doi.org/10.7156/najms.2012.054232.

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32

Oladimeji, Ashaolu Victoria, and MF Valan. "Newer Plant based drug molecules with theraputic potential to combat alcohol dependency." Journal of Pharmacognosy and Phytochemistry 9, no. 3 (May 1, 2020): 693–96. http://dx.doi.org/10.22271/phyto.2020.v9.i3k.11352.

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33

Bahreini, Z., J. C. Gregor, and P. Walton-Mennill. "A119 THERAPUTIC DRUG MONITORING IN PATIENTS WITH ULCERATIVE COLITIS TREATED WITH GOLIMUMAB." Journal of the Canadian Association of Gastroenterology 1, suppl_2 (February 2018): 181. http://dx.doi.org/10.1093/jcag/gwy009.119.

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34

Lee, H., Y. Kim, J. H. Ryu, and W. Y. Kim. "336 p53 dependent chemopreventive and theraputic activity on lung cancer by Pterostilbene." European Journal of Cancer 51 (September 2015): S66. http://dx.doi.org/10.1016/s0959-8049(16)30200-3.

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35

Ohtani, Hitomi, Sachiko Okamoto, Kaoru Makino, Hitomi Hirakawa, Mayumi Hiraoka, Kyomi Nishigaki, Nobuko Takemura, et al. "Advantage of theraputic blood purification in outpatients with end-stage renal diseases." Journal of Japanese Society for Dialysis Therapy 19, no. 11 (1986): 1021–24. http://dx.doi.org/10.4009/jsdt1985.19.1021.

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36

Barnaulov, Oleg Dmitriyevich. "The positive gonadotropic effect phytotherapy patients with multiple sclerosis and other neurological diseases." Reviews on Clinical Pharmacology and Drug Therapy 12, no. 3 (September 15, 2014): 70–82. http://dx.doi.org/10.17816/rcf12370-82.

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There are some examples of positive influence phytotherapy on the reduced reproductive functions of men with multiple sclerosis (MS) and other neurogenic diseases in this article. The prescriptions of polycomponent species wich infusions provided high theraputic effect in treating patients with MS and some other syndroms are cited. The explanation of biologically determinated interest in animal’s reproduction is given for some plants. Such approach an exploring of unity flora and fauna law is confirmation of high significance the theory condition nonspecificolly heightened resistance of organism, provoked by plants. This theory was worked out by greate russian pharmacologist N. V. Lasarev and his school.
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37

Kaufmann, Anthony M., William C. Halliday, Michael West, Derek Fewer, and Ian Ross. "Periodontoid Synovial Cyst Causing Cervico-medullary Compression." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 23, no. 3 (August 1996): 227–30. http://dx.doi.org/10.1017/s0317167100038579.

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AbstractBackground: Periodontoid synovial cysts are rare lesions which may produce symptomatic cervico-medullary compression. Method: We report such a patient, whose progressive neurological deterioration required surgical treatment by transoral odontoidectomy and decompression. Results: The diagnostic and theraputic interventions are described, including a lumbar puncture which precipitated a transient loss of consciousness and respiratory arrest. Surgery achieved clinical improvement, without complications or need for operative stablization. Detailed neuropathology is presented, as well as a literature review. Conclusion: Appropriate neuroradiological assessment is required in patients with suspected cervico-medullary compression, and symptomatic periodontoid synovial cysts may respond well to transoral surgical decompression.
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38

Khadir, M. M., and P. Westesson. "Feasibility of utilizing CT- guided theraputic pudendal nerve block in treating pudendal neuralgia." Journal of Vascular and Interventional Radiology 25, no. 3 (March 2014): S193. http://dx.doi.org/10.1016/j.jvir.2013.12.521.

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39

Stones, M. J., Christine Rattenbury, and Albert Kozma. "Application of a nonlinear mathematical model to data on a successful theraputic intervention." Social Indicators Research 31, no. 1 (January 1994): 47–61. http://dx.doi.org/10.1007/bf01086513.

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40

Poudel, Parashu Ram. "Physics in Medical Science." Himalayan Physics 2 (July 31, 2011): 43–46. http://dx.doi.org/10.3126/hj.v2i2.5210.

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The domain of Physics covers vast area of scientific knowledge. Basic research on assemblies of atomic or nuclear radiation and gyromagnetic moments led to powerful technique for studying molecular structure as well as solid lattices. It led to invention and development of modern medical diagnostic and theraputic tools which have revolutionized the medical practices. Advancement in medical researches as seen today will be well-nigh impossible without the use of the finding of Physics. The funding made on Physics is in fact another way of funding made on human health.Keywords: Radioactivity; Crystallography; Radioimmune assay; MRI; CAT; PETThe Himalayan PhysicsVol.2, No.2, May, 2011Page: 43-46Uploaded Date: 1 August, 2011
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41

Paoletti, Lawrence C., Julieanne Pinel, Ariane K. Rodewald, and Dennis L. Kasper. "Theraputic Potential of Human Antisera to Group B Streptococcal Glycoconjugate Vaccines in Neonatal Mice." Journal of Infectious Diseases 175, no. 5 (May 1997): 1237–39. http://dx.doi.org/10.1086/593678.

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42

Neff, Lucas P., Justin M. Allman, and James H. Holmes. "The use of theraputic plasma exchange (TPE) in the setting of refractory burn shock." Burns 36, no. 3 (May 2010): 372–78. http://dx.doi.org/10.1016/j.burns.2009.05.006.

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43

Fomina, D. S., T. N. Markova, and V. V. Sadovskaya. "Bronchial asthma and the vitamin D deficiency." Clinical Medicine (Russian Journal) 96, no. 7 (December 15, 2018): 590–96. http://dx.doi.org/10.18821/0023-2149-2018-96-7-590-596.

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The variety of tissue cells express receptors of vitamin D. The possible causative connection between lack of vitamin D and a number of inflammatory diseases such as bronchial asthma has stimulated interest in the potentially positive effects of vitamin D in the theraputic schemes. Conflicting data was demonstrated by numerous studies concerning the relationship of vitamin D and development of asthma . Most of them stress attention on the lack of studies with targeting population excluding subclasters and phenotypes of bronchial asthma, especially groups associated with low levels of vitamin D obesity, COPD and asthma, atopic patients. The question of prescribing of vitamin D in asthma, in the case of laboratory-proven deficiency or lack of vitamin D can be an option in therapy.
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44

Rahman, Mostafizur, Adnan Y. Choudhury, and S. M. Abdullah A. Mamun. "Theraputic Respponse Patterns of Severe Acute Asthma Patients to High and Cumulative Doses of Salbutamol." Chest 126, no. 4 (October 2004): 814S. http://dx.doi.org/10.1378/chest.126.4_meetingabstracts.814s.

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45

Chen, Lei, Lin Liu, Tao Wang, Yong-chun Shen, and Fu-qiang Wen. "Receptor for Advanced Glycation End Products: A New Theraputic Target for Chronic Obstructive Pulmonary Disease?" Archives of Medical Research 44, no. 1 (January 2013): 75–76. http://dx.doi.org/10.1016/j.arcmed.2012.12.003.

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46

S. Abdel Gany, Zaynab, and Mayasaa F. Mahdi. "Cytotoxic Assay of Nigella sativa Leaf Callus Extract (Thymol) on Hep-2 Cell Line Using ELISA Assay." Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512) 17, no. 2 (March 30, 2017): 63–66. http://dx.doi.org/10.31351/vol17iss2pp63-66.

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Extract from cell culture of medicinal plant like Nigella sativa have been assessed for its cytotoxic properties. Thymol is likely responsible for the theraputic effects of Nigella sativa leaf callus extract. In this short study the inhibitory effect of Nigella sativa leaf callus extract (Thymol) has been studied on Human Lorgnx Epidrmoid Carcinoma (Hep-2) cell line during different exposure period of time (24, 48 and 72 hrs.) using different concentration of the extract (1000, 500, 400, 300, 200 and 100 µg/ml). The optical density of the Hep-2 cells has been readed on 492 nm wave length. Thymol –induced cytotoxicity was (500 µg/ml) which inhibit cell growing compared to the control and this ratio increased at the 48 hrs of exopsure and stopped at 72 hrs. Key wards: Nigella sativa, callus extract, cell line, ELISA assay.
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47

Jahromi, Amin H., and Steven C. Zimmerman. "Rational Design of Potent Dimeric Ligands as Potential Theraputic Agents for Myotonic Dystrophy Type I (DM1)." Biophysical Journal 102, no. 3 (January 2012): 483a. http://dx.doi.org/10.1016/j.bpj.2011.11.2647.

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48

Koochek, M. H., R. J. Mazlouman, and H. Gafari. "The effects of chloride on rat lung: preventive and theraputic effects of lung exposure to hydrocortisone." European Journal of Pharmacology 183, no. 4 (July 1990): 1186. http://dx.doi.org/10.1016/0014-2999(90)94276-4.

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49

Elsalamawy, D. O. A. "PO17-TU-07 Theraputic effect of interferon alpha on extra hepatic complications of hepatitis C virus infection." Journal of the Neurological Sciences 285 (October 2009): S241. http://dx.doi.org/10.1016/s0022-510x(09)70919-0.

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50

Matsumoto, K., H. Kikuchi, S. Kano, H. Iri, H. Takahashi, and M. Umino. "Automated determination of drugs in serum by liquid chromatography with column-switching. I. Separation of antiepileptic drugs and metabolites." Clinical Chemistry 34, no. 1 (January 1, 1988): 141–44. http://dx.doi.org/10.1093/clinchem/34.1.141.

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Abstract:
Abstract This is a fully automated system for determining six common antiepileptic drugs and two principal metabolites of carbamazepine in serum. It is based on "high-performance" liquid chromatography (HPLC), with column switching. TSKprecolumn BSA-ODS and TSKgel ODS-120A (both from Toyo Soda) were used as the precolumn and analytical column, respectively. The former contains octadecylsilyl resins treated with bovine serum albumin (BSA), and does not adsorb macromolecules such as serum proteins but retains small lipophilic molecules such as antiepileptic drugs. Serum samples are directly injected onto the precolumn. After washing out the serum proteins from the precolumn with sodium phosphate buffer, we switch the column connections to introduce the retained substances onto the analytical column and elute with a step-gradient of acetonitrile/sodium phosphate buffer. The high analytical recovery (95-102%) and the reproducibilities (CV less than 5% within-run) indicate that this system is suitable for use in theraputic drug monitoring in clinical laboratories.
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