Academic literature on the topic 'Theraputic use'
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Journal articles on the topic "Theraputic use"
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Castro, M. Regina. "Thyroid Nodules—Management Dilemmas and Theraputic Considerations." US Endocrinology 00, no. 01 (2005): 1. http://dx.doi.org/10.17925/use.2005.00.01.1f.
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Castro, M. Regina. "Thyroid Nodules - Management Dilemmas and Theraputic Considerations." US Endocrinology 00, no. 01 (2005): 68. http://dx.doi.org/10.17925/use.2005.00.01.68.
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Thyroid nodules are very common in clinical practice, with an overall prevalence that varies from 4% by palpation to 67% by ultrasonography. The annual incidence by palpation has been estimated at 0.09% by the Framingham study,1which translates into approximately 300,000 new nodules in the US in 2005. Despite their high frequency, only a small fraction (~5%) of thyroid nodules harbor cancer. Because only malignant or large, symptomatic nodules will require surgical excision, a systematic approach to their evaluation is important to avoid unnecessary surgery. Certain aspects in the evaluation and management of thyroid nodules remain controversial or represent clinical dilemmas.
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Guancial, Elizabeth A., Vinay S. Mahajan, Ronald P. McCaffrey, and Neal Lindeman. "Theraputic Monoclonal Antibody Interference In Immunofixation Electrophoresis." Blood 116, no. 21 (November 19, 2010): 4996. http://dx.doi.org/10.1182/blood.v116.21.4996.4996.
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Abstract Abstract 4996 The application of monoclonal antibodies represents an increasingly powerful weapon in the arsenal against hematologic diseases. With the advent of new therapies come previously unrecognized laboratory interference that if not properly identified could have clinical repercussions. We encountered two patients, neither of whom had a history of plasma cell dyscrasia, who underwent treatment with rituximab for immune thrombocytopenic purpura (ITP) and were discovered to have a monoclonal IgG kappa band on serum protein electrophoresis (SPEP) followed by immunofixation (IFX). Both patients had severe, steroid-resistant ITP and received rituximab on an empiric basis, at a weekly dose of 375 mg/m2 IV. In Patient #1, an evaluation for secondary causes of thrombocytopenia included SPEP and IFX. The IFX yielded a faint, atypical IgG kappa band that migrated to the far cathodal zone of the gel. No band was seen on SPEP alone. Since the patient was treated with rituximab the day before these studies were performed, we considered the possibility that the IgG kappa band was due to circulating rituximab. Rituximab is a chimeric antibody composed of human IgG1 kappa chain constant regions and heavy- and light-chain variable regions from a murine anti-CD20 antibody. The elimination half-life of this therapeutic antibody increases with subsequent doses and is approximately 60 hours for the first dose and 174 hours for the fourth dose (range 26 to 442 hours). An aliquot of rituximab was obtained from pharmacy and analyzed by SPEP/IFX, showing an IgG kappa monoclonal protein band identical to the M-protein in the patient's serum. Repeat assessment of serum from this patient obtained immediately prior to her fourth treatment with rituximab demonstrated that the IgG kappa paraprotein was less intense on IFX compared to the first IFX. Several hours after the fourth rituximab infusion was completed, a more intense band corresponding to the IgG kappa paraprotein was detected again on IFX. In Patient #2, who also received rituximab for steroid-resistant ITP, a similar circulating rituximab-related protein was detected on IFX performed one hour after his fourth rituximab infusion. IFX performed on a sample obtained immediately before treatment did not demonstrate a paraprotein, and testing one week after treatment showed that the band had resolved. We believe that awareness of the presence of a faint monoclonal protein by SPEP/IFX following recent administration of rituximab is important to avoid unnecessary further evaluation for a pathologic monoclonal gammopathy. Alternatively, if suspicion exists, SPEP/IFX should be conducted prior to the initiation of treatment with rituximab or after the treatment course is completed in order to avoid uncertainty. Furthermore, it is important to be cognizant of this finding in patients on maintenance rituximab for an indolent lymphoma and an associated paraprotein who may undergo interval monitoring of the monoclonal gammopathy. It is possible that a similar phenomenon may be seen with other therapeutic monoclonal antibodies with a dosing regimen and half-life that is similar to rituximab, such as cetuximab, a monoclonal antibody directed against the epidermal growth factor receptor. Finally, the presence of a characteristic band on immunofixation may allow for the qualitative assessment of the presence of a therapeutic monoclonal antibody in the serum. Further studies are necessary to determine the sensitivity and specificity of such a laboratory test. Disclosures: Off Label Use: Rituximab is an anti-CD20 chimeric antibody and is used for the treatment of immune thrombocytopenic purpura.
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Neff, Lucas P., Justin M. Allman, and James H. Holmes. "The use of theraputic plasma exchange (TPE) in the setting of refractory burn shock." Burns 36, no. 3 (May 2010): 372–78. http://dx.doi.org/10.1016/j.burns.2009.05.006.
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Poudel, Parashu Ram. "Physics in Medical Science." Himalayan Physics 2 (July 31, 2011): 43–46. http://dx.doi.org/10.3126/hj.v2i2.5210.
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The domain of Physics covers vast area of scientific knowledge. Basic research on assemblies of atomic or nuclear radiation and gyromagnetic moments led to powerful technique for studying molecular structure as well as solid lattices. It led to invention and development of modern medical diagnostic and theraputic tools which have revolutionized the medical practices. Advancement in medical researches as seen today will be well-nigh impossible without the use of the finding of Physics. The funding made on Physics is in fact another way of funding made on human health.Keywords: Radioactivity; Crystallography; Radioimmune assay; MRI; CAT; PETThe Himalayan PhysicsVol.2, No.2, May, 2011Page: 43-46Uploaded Date: 1 August, 2011
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Mueller, Joseph, Ryan Yao, Kim Selting, Catherine Best-Popescu, Brendan Harley, and Sara Pedron-Haba. "Abstract A045: Engineered systems for tumor modeling facilitate the assessment of theraputic interventions." Cancer Research 84, no. 5_Supplement_1 (March 4, 2024): A045. http://dx.doi.org/10.1158/1538-7445.brain23-a045.
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Abstract Brain cancers remain some of the most challenging tumors to treat. The goal of our research is to use a 3D in vitro model to acquire in-depth understanding of the unique environment of brain tumors in order to find new biomarkers of disease and develop more efficient therapeutic approaches. Glioblastomas (GBM) present a very poor prognosis, they exhibit high infiltration into brain parenchyma, impairing surgical resection and leading to recurrence. The recurrent tumor is predominantly more aggressive and resistant to available therapeutic strategies. Brain extracellular matrix (ECM) plays a key role in glioblastoma invasion and therapeutic resistance. In particular, the aberrant biosynthesis of the main component of brain ECM, hyaluronic acid (HA), has been associated to pathological conditions. We investigate the influence of tumor extracellular microenvironment in glioblastoma progression. We focus on the tumor-associated HA biosynthesis in response to biophysical alterations, such as hypoxia and stiffness, and after radio and chemotherapeutic interventions. The ability to manipulate tumor ECM can improve therapeutic outcomes and restrict glioblastoma growth and infiltration. Citation Format: Joseph Mueller, Ryan Yao, Kim Selting, Catherine Best-Popescu, Brendan Harley, Sara Pedron-Haba. Engineered systems for tumor modeling facilitate the assessment of theraputic interventions [abstract]. In: Proceedings of the AACR Special Conference on Brain Cancer; 2023 Oct 19-22; Minneapolis, Minnesota. Philadelphia (PA): AACR; Cancer Res 2024;84(5 Suppl_1):Abstract nr A045.
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Aknouk, Mina, and Kenny Chiu. "S2608 Hemospray, a Novel Theraputic Use to Control Rectal Bleeding in a Case of Refractory Hemorrhagic Radiation Proctitis." American Journal of Gastroenterology 117, no. 10S (October 2022): e1727-e1728. http://dx.doi.org/10.14309/01.ajg.0000867072.17772.0c.
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Matsumoto, K., H. Kikuchi, S. Kano, H. Iri, H. Takahashi, and M. Umino. "Automated determination of drugs in serum by liquid chromatography with column-switching. I. Separation of antiepileptic drugs and metabolites." Clinical Chemistry 34, no. 1 (January 1, 1988): 141–44. http://dx.doi.org/10.1093/clinchem/34.1.141.
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Abstract This is a fully automated system for determining six common antiepileptic drugs and two principal metabolites of carbamazepine in serum. It is based on "high-performance" liquid chromatography (HPLC), with column switching. TSKprecolumn BSA-ODS and TSKgel ODS-120A (both from Toyo Soda) were used as the precolumn and analytical column, respectively. The former contains octadecylsilyl resins treated with bovine serum albumin (BSA), and does not adsorb macromolecules such as serum proteins but retains small lipophilic molecules such as antiepileptic drugs. Serum samples are directly injected onto the precolumn. After washing out the serum proteins from the precolumn with sodium phosphate buffer, we switch the column connections to introduce the retained substances onto the analytical column and elute with a step-gradient of acetonitrile/sodium phosphate buffer. The high analytical recovery (95-102%) and the reproducibilities (CV less than 5% within-run) indicate that this system is suitable for use in theraputic drug monitoring in clinical laboratories.
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Joshi, SN, M. Chaudhary, D. Bhattarai, S. Gnyawali, G. S. Shrestha, and P. Adhikari. "Theraputic application if Poly-2-hydroxy ethyl mathacrylate contact lens in various ocular surface disorders among Nepalese population." Journal of Institute of Medicine Nepal 37, no. 2 (August 30, 2015): 35–39. http://dx.doi.org/10.59779/jiomnepal.713.
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Introduction: Therapeutic contact lens (TCL) is indicated to relieve pain, promote corneal wound healing, provide mechanical protection and support, maintain corneal hydration, improve vision and seal or splint cornea in various ocular surface disorders. Till date no study has been reported about use of contact lenses for these purposes in Nepalese population. is study thus aims to evaluate the outcome of TCL in ocular surface disorders in Nepalese population. Methods: A prospective analysis of patients fitted with TCL for various ocular surface disorders was done at B.P. Koirala Lions centre for Ophthalmic Studies. All the subjects were fitted with Poly-2-hydroxy ethyl methacrylate (70% water content); information on clinical conditions were evaluated and recorded at initial and final treatment visit. Results: Of 57 eyes fitted with TCL, corneal laceration caused by mechanical injury (22.8%) and vernal keratoconjunctivitis (21.1%) were the most common ocular surface disorders. The common indications for applying TCLs were to alleviate pain and discomfort (31.5%) and corneal thinning impending to perforation (26.3%). Subjects’ clinical conditions and symptoms were resolved partially to completely in 89.4%. Dry eye was a common cause of contact lens associated therapeutic failure. Conclusion: Poly-2-hydroxy ethyl methacrylate contact lenses are safe and effective in alleviating symptoms and healing of various ocular surface disorders in Nepalese population.
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Mentrup, Heather, Anna Ramos, Elizabeth Novak, Steven Ballesteros, Erin Crawford, Meredith Flanagan, and Kevin Mollen. "MITOCHONDRIAL TURNOVER IS ELEVATED IN RESPONSE TO INTESTINAL INFLAMMATION AND IS AMENABLE TO THERAPUTIC TARGETING VIA UROLITHIN A." Inflammatory Bowel Diseases 30, Supplement_1 (January 25, 2024): S3—S4. http://dx.doi.org/10.1093/ibd/izae020.008.
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Abstract Inflammatory bowel disease (IBD) is a complex, multifactorial set of diseases defined by chronic and relapsing inflammation of the gut. Changes in oxidative stress, inflammation, and metabolism are central to the disease process, linking mitochondrial health to IBD pathogenesis. Mitophagy is a quality-control mechanism that selectively removes dysfunctional mitochondria. Multiple mitophagy pathways co-exist in the intestine, including the canonical PINK1/PARKIN pathway and NIX. We have previously shown that NIX is increased in IBD, removing damaged mitochondria in the epithelium. Whether this translates to a physiologic increase in mitochondrial turnover remains unanswered. We hypothesized that mitophagy within the intestinal epithelium represents a key homeostatic response to inflammation. To study this hypothesis, we employed the use of a novel transgenic mouse expressing the pH-dependent fluorescent protein, mt-Keima, tethered to the mitochondria. Adult mt-Keima mice were subjected to chemically induced colitis (3% DSS) for 7 days to induce intestinal inflammation. In vivo mitophagic flux, measured via live-cell confocal microscopy, was increased nearly 4-fold (n=3, p<0.05) in DSS-treated animals compared to controls. Despite this consistent elevation, NIX expression varied in both human and mouse tissue, suggesting that other mitophagy pathways, like PARKIN, may be involved. Interestingly, activated PARKIN (pSer65-PARKIN) was higher in inflamed tissues of humans and mice as compared to controls, though variation was present. To determine the functional importance of PARKIN, Parkin-/- mice were subjected to a 7-day treatment of 2% DSS. These mice developed a more severe colitis, suggesting that Parkin-mediated mitophagy contributes to the mitochondrial damage response in IBD. These data collectively indicate that mitophagy is elevated in IBD, and both NIX and PARKIN likely work in parallel to respond to the elevated mitophagic demand. Interestingly, both NIX and pSer65-PARKIN expression are co-expressed in human control tissues, while both were generally expressed in inflamed biopsies, and at higher levels. We speculate that the mechanism of mitophagy may not necessarily be important, but that it is elevated in response to intestinal inflammation. To address this aim, we administered a known mitophagy inducer, urolithin A, to mice on a 7-day course of DSS. Urolithin A + DSS-treated mice had elevated NIX and pSer65-PARKIN expression compared to vehicle + DSS controls. This elevation correlated with decreased disease activity and improved O2 mitochondria respiration. We conclude that mitophagy is an imperative homeostatic response to remove superfluously damaged mitochondria in IBD and is amenable to therapeutic intervention. Elevating mitophagic flux might be a potential therapeutic option to help improve disease outcomes in IBD.
Dissertations / Theses on the topic "Theraputic use"
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Sibole, Janet Marie. "Induction and expression of cocaine-induced behavioral sensitization: Modulation by a partial D₂-like agonist." CSUSB ScholarWorks, 2003. https://scholarworks.lib.csusb.edu/etd-project/2438.
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The purpose of this study was to investigate whether a partial D₂-like dopamine agonist (i.e. terguride) would block the induction or expression of cocaine-induced behavioral sensitization in pre-weanling rats. The ability of terguride to induce behavioral sensitization was also examined, as partial D₂-like agonists have agonistic actions in cases of low dopaminergic tone.
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Fatemi, Jaleh. "An exploratory study of peak experience and other positive human experiences and writing." Texas A&M University, 2004. http://hdl.handle.net/1969.1/1368.
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This study analyzes and reports on the characteristics of writing-triggered
peak experience and other positive human experiences and explores some
possible factors that can bring about such moments. Three basic questions were
explored: Can writing trigger peak experience and other positive human
experiences? How are writing-triggered peak experience and other positive
human experiences best described? What factors influence the occurrence of
writing-triggered peak experience and other positive human experiences?
Participants were asked to write about their happiest moment in writing. The
sample consisted of 270 students enrolled in undergraduate writing classes at a
major southwestern university. Of 270 participants, 119(44%) reported having
had at least one peak experience or similar positive human experience as a result
of writing. Protocols reporting peak experience and other positive human
experiences in writing were analyzed for content, yielding a total of 14 descriptive
attributes. The participants described their writing experiences as flow of the
words, the process of writing is its own reward, peak performance, clarity,
disappearance of negative states of mind, and enhanced sense of power and
personal worth. Content analysis also yielded 13 possible triggers of peak
experience and other positive human experiences including self-expression,
realization, free writing, use of writing for introspection, and creative and
inspirational writing. In addition, personal orientation was explored as a possible
trigger of peak experience and other positive human experiences using a 16-item
questionnaire.
Factor analysis results yielded four factors: (1) aesthetic creative expressive
writing, (2) writing as a thinking and problem solving tool (3) self-discovery, and
(4) not interested in writing. Factor one accounted for the highest variance (37%).
The common elements in this factor were expressive writing, self-related writing
and creative poetic writing with poetic and creative writing having the highest
loading.
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"Construction of a Recombinant Immunotoxin." University of Technology, Sydney. Faculty of Science, 1995. http://hdl.handle.net/2100/270.
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In recent years a number of therapeutically useful immunotoxins have been produced using recombinant gene technology. In general, this involves fusion of a toxin gene with sequence encoding a variety of clinically relevant proteins or peptides. Using these techniques a recombinant immunotoxin has been engineered by fusing the genes encoding an antibody fragment with the sequence of a small cytolytic peptide, melittin. The antibody fragment consists of the antigen binding site derived from a murine monoclonal antibody K- 1-21, which binds to human free kappa light chains and recognises a specific epitope (KMA) expressed on the surface of human myeloma and lymphoma cells. The toxic portion of the molecule is melittin, a 26 amino acid, membrane lytic peptide which is a major component of bee venom. Using PCR a single chain Fv (scFv) was constructed by linking VH and VL genes with an oligonucleotide encoding a flexible, hydrophilic peptide. The melittin gene was synthesised as an oligonucleotide and extended by PCR. Nucleotide sequence encoding a linker peptide was added to the 5' end and a primer encoding a FLAG peptide was used to extend the 3' end. This gene construct was then ligated into the recombinant expression vector, pPOW scFv, to create the fusion gene encoding the recombinant immunotoxin. The gene construct was expressed in the periplasm of E.coli (TOPP2) using the secretion signal pelB . Expression of the foreign protein was monitored by western blot using a monoclonal antibody which recognises the FLAG peptide encoded at the carboxy terminal region of the gene construct. Expression of the recombinant immunotoxin was optimised and the resulting protein was purified using anti-FLAG M2 affinity chromatography. Antigen binding activity was assessed by ELISA and flow cytometry using a human myeloma cell line, HMy2, which expresses the KMA antigen.Binding of the immunotoxin to a control human cell line, K562, which does not express KMA on the cell surface was also assessed. The results indicated that the recombinant immunotoxin retained antigen binding specificity and it was cytotoxic towards the target cell line (HMy2).
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Cho, Min-hee. "Pharmacokinetics, hepatic extraction, and renal disposition of phosphorothioate oligodeoxynucleotides." 2002. http://wwwlib.umi.com/cr/utexas/fullcit?p3077622.
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"Construction of a recombinant immunotoxin." Thesis, University of Technology, Sydney. Faculty of Science, 1995. http://hdl.handle.net/10453/20069.
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University of Technology, Sydney. Faculty of Science.In recent years a number of therapeutically useful immunotoxins have been produced using recombinant gene technology. In general, this involves fusion of a toxin gene with sequence encoding a variety of clinically relevant proteins or peptides. Using these techniques a recombinant immunotoxin has been engineered by fusing the genes encoding an antibody fragment with the sequence of a small cytolytic peptide, melittin. The antibody fragment consists of the antigen binding site derived from a murine monoclonal antibody K- 1-21, which binds to human free kappa light chains and recognises a specific epitope (KMA) expressed on the surface of human myeloma and lymphoma cells. The toxic portion of the molecule is melittin, a 26 amino acid, membrane lytic peptide which is a major component of bee venom. Using PCR a single chain Fv (scFv) was constructed by linking VH and VL genes with an oligonucleotide encoding a flexible, hydrophilic peptide. The melittin gene was synthesised as an oligonucleotide and extended by PCR. Nucleotide sequence encoding a linker peptide was added to the 5' end and a primer encoding a FLAG peptide was used to extend the 3' end. This gene construct was then ligated into the recombinant expression vector, pPOW scFv, to create the fusion gene encoding the recombinant immunotoxin. The gene construct was expressed in the periplasm of E.coli (TOPP2) using the secretion signal pelB . Expression of the foreign protein was monitored by western blot using a monoclonal antibody which recognises the FLAG peptide encoded at the carboxy terminal region of the gene construct. Expression of the recombinant immunotoxin was optimised and the resulting protein was purified using anti-FLAG M2 affinity chromatography. Antigen binding activity was assessed by ELISA and flow cytometry using a human myeloma cell line, HMy2, which expresses the KMA antigen.Binding of the immunotoxin to a control human cell line, K562, which does not express KMA on the cell surface was also assessed. The results indicated that the recombinant immunotoxin retained antigen binding specificity and it was cytotoxic towards the target cell line (HMy2).
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Ernst, Anthony Joseph. "The client's perspective of naltrexone phamacotherapy a qualitative study /." 2002. http://wwwlib.umi.com/cr/utexas/fullcit?p3077636.
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Breytenbach, Frieda. "Diagnostiese waarde van klei as projeksiemedium." Thesis, 2009. http://hdl.handle.net/10500/3368.
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Text in Afrikaanshe goal of this research study is to determine whether clay has any diagnostic value to the Educational Psychologist. The phenomenon of claywork with children has been examined by literature to determine whether this subject has been researched before. The developmental phases in claywork and the development of clayfigures are discussed, as well as the clay techniques which are applied by children. A comparison between clay as a three-dimensional medium and drawings as two-dimensional medium is made. The ways of application of clay are discussed by means of case studies. The general value of clay for the Educational Psychologist is also mentioned. On the grounds of certain short-comings in the literature study, "The Clay-feelingstory technique" is initiated and applied. For the empirical study eighty learners in the foundation phase, aged between five and nine years, were involved. Random sampling was used. This research study uses the combined method design in order to better understand the phenomenon of clay projections. Although the study is mainly qualitative in nature, some data is quantified. The research results prove that clay projections have diagnostic value, concerning the child's verbal and non-verbal messages, the way he applies clay techniques, by decoding his symbolic messages, emotions come to the fore, actions are portrayed and described, relations are revealed, themes come to the fore and needs are expressed. It also seems that clay projections can be taken in group context as an identification medium to help the child in need. It also seems that clay projections can be applied as a supplementary projection medium and that hypothesis can be verified with other exploratory media. Guidelines are given for the application and interpretation of clay as projection medium.
Educational Studies
D.Ed. (Sielkundige Opvoedkunde)
Books on the topic "Theraputic use"
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R, Owens D., ed. Basal insulin therapy in type 2 diabetes mellitus. London: Aesculapium Ltd., 2004.
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Suren. Cyclopedia of Yoga. Meerut, India: Saru Pub. House, 1992.
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Hewson, Mitchell L. Horticulture as therapy: A practical guide to using horticulture as a theraputic tool. Guelph, Ont: Mitchell L. Hewson, 1994.
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Müller-Jung, Joachim. Das Ende der Krankheit: Die neuen Versprechen der Medizin. München: Hanser, 2014.
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Snow, Otto. THC & tropacocaine. Spring Hill, Fl: Thoth, 2004.
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Bennett, Catherine. The theraputic use of cannabis for multiple sclerosis and associated muscle spasticity. Oxford: Oxford Brookes University, 2003.
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Lerner, Hilel. ha-Madrikh ha-shimushi li-terufot betiyot ṭivʻiyot. Hod ha-Sharon: Asṭrolog, 2013.
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Chevallier, Andrew. Herbal remedies handbook. Taiwan: Owl, 2003.
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Chevallier, Andrew. Tadawi bil ashaab. Beirut: Academia International, 2001.
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Loe, Theresa. The herbal home companion. New York: Kensington Books, 1996.
Find full textBook chapters on the topic "Theraputic use"
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DeNapoli, Antoinette. "In Search of the Sadhu’s Stone: Metals and Gems as Theraputic Technologies of Transformation in Vernacular Aesceticism in North India." In Soulless Matter, Seats of Energy: Metals, Gems and Minerals in South Asian Traditions, 143–73. Equinox Publishing, 2016. http://dx.doi.org/10.1558/equinox.29656.
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“In the middle of these mountains is our immortality,” said Shabari Bai, a female Hindu renouncer (sadhu) from a Bhil (tribal) community in North India. Located in Chirva village (Udaipur district), Rajasthan, Shabari Bai’s ashram is nestled in the Aravalli Mountains, one of the oldest mountain chains in South Asia. She continued, “The earth [bhumi] is the most precious life [jiv] on the planet. She is alive just as we are alive. She bears the pain of the world and has all the knowledge [jnan] that will heal our suffering and keep us from destroying ourselves.” Shabari Bai’s incisive statement calls attention to the earth and, more specifically, to landforms such as mountains, as the seat of energy, power, and salvific knowledge. More significantly, Shabari Bai suggests that mountains possess a form of consciousness (jiv) and, thus, represent a “precious” natural resource—or life—precisely because they contain invaluable substances such as metals, minerals, and gems that promote the health and healing of all life on the planet, including the planet itself. Like Shabari Bai, sadhus in the North Indian state of Rajasthan, in which I conducted extensive field research with Hindu sadhus from the Shaiva (Dashanami and Nath) and Vaishnava (Ramananda/Tyagi) renouncer traditions, associate naturally occurring substances like metals, minerals, and gems with power and immortality and use them in their everyday ritual/healing practices. In my experience, preferring naturopathic—or, in Indian terms, Ayurvedic—methods over allopathic methods, sadhus, men and women, commonly wear stones, gems, and metals on their bodies as an efficacious means to heal, cure, and prevent ailments from poor digestion to anaemia. To take an example, according to many of the sadhus I knew, wearing copper on the big toe aids digestion. In another context, following an almost fatal dog attack and only after allopathic methods failed, Kailash Das, a Ramanandi (Tyagi) sadhu, started to wear thick silver rings on each of her toes. “It keeps the veins open and causes the blood to move in my feet. Since I’ve been wearing these [rings], I suffer no pain in my feet at all.” Based on over a decade of ethnographic fieldwork in Rajasthan, this essay describes and analyzes sadhus’ knowledge and use of metals, minerals, and gems in order to shed light on a level of vernacular practice and experience that has been underrepresented in the scholarship on sannyas in South Asia. Special attention is paid to the sadhus’ gendered representations of metals, minerals, and gems and the ways that their practices shape and reconfigure the more standard definitional parameters for what sannyas is all about in contemporary India. The essay is divided into two parts. Part 1 analyzes what I have characterized as the sadhus’ “rhetoric of renunciation,” the stories (kahani) and songs (bhajan) that they perform about the earth, its properties, and humans’ responsibility to the planet. In addition, this section explores sadhus’ ideas about ecological sustainability in a consumer-based economy through means of their performances. Part 2 examines the sadhus’ use and classification of metals, minerals, and gems, the deities associated with these substances, the problems they are thought to cure and/or prevent, and the sadhus’ personal experiences of illness that catalyzed their knowledge and use of metals, minerals, and gems. In sum, this essay contributes new research to academic studies of sannyas in South Asia and shows that sadhus draw on indigenous knowledge about minerals, metals, and gems in their practices both to address and redress the deleterious effects that Rajasthan’s mining industry is wreaking on the earth in a rapidly changing, postindustrial India.
Conference papers on the topic "Theraputic use"
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Zoabi, A., and H. Awadie. "Median Arcuate Ligament Syndrome(MALS) – A Case Report On The Use Of EUS As A Diagnostic And Therapuetic Tool Prior To Definitive Sugery." In ESGE Days 2023. Georg Thieme Verlag KG, 2023. http://dx.doi.org/10.1055/s-0043-1765736.
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