Journal articles: 'TFCG'

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Sharma, Nitya, Kathryn Pellegrini, Veronique Ouellet, Felipe Giuste, Selvi Ramalingam, Kenneth Watanabe, Eloise Adam-Granger, et al. "Identification of the Transcription Factor Relationships Associated with Androgen Deprivation Therapy Response and Metastatic Progression in Prostate Cancer." Cancers 10, no. 10 (October 11, 2018): 379. http://dx.doi.org/10.3390/cancers10100379.

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Background: Patients with locally advanced or recurrent prostate cancer typically undergo androgen deprivation therapy (ADT), but the benefits are often short-lived and the responses variable. ADT failure results in castration-resistant prostate cancer (CRPC), which inevitably leads to metastasis. We hypothesized that differences in tumor transcriptional programs may reflect differential responses to ADT and subsequent metastasis. Results: We performed whole transcriptome analysis of 20 patient-matched Pre-ADT biopsies and 20 Post-ADT prostatectomy specimens, and identified two subgroups of patients (high impact and low impact groups) that exhibited distinct transcriptional changes in response to ADT. We found that all patients lost the AR-dependent subtype (PCS2) transcriptional signatures. The high impact group maintained the more aggressive subtype (PCS1) signal, while the low impact group more resembled an AR-suppressed (PCS3) subtype. Computational analyses identified transcription factor coordinated groups (TFCGs) enriched in the high impact group network. Leveraging a large public dataset of over 800 metastatic and primary samples, we identified 33 TFCGs in common between the high impact group and metastatic lesions, including SOX4/FOXA2/GATA4, and a TFCG containing JUN, JUNB, JUND, FOS, FOSB, and FOSL1. The majority of metastatic TFCGs were subsets of larger TFCGs in the high impact group network, suggesting a refinement of critical TFCGs in prostate cancer progression. Conclusions: We have identified TFCGs associated with pronounced initial transcriptional response to ADT, aggressive signatures, and metastasis. Our findings suggest multiple new hypotheses that could lead to novel combination therapies to prevent the development of CRPC following ADT.

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Cowin, A. J., J. R. E. Davis, and S. P. Bidey. "Transforming growth factor-β1 production in porcine thyroid follicular cells: regulation by intrathyroidal organic iodine." Journal of Molecular Endocrinology 9, no. 3 (December 1992): 197–205. http://dx.doi.org/10.1677/jme.0.0090197.

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ABSTRACT The present studies have demonstrated the production of transforming growth factor-β1 (TGF-β1) by porcine thyroid follicular cells (TFCs) maintained in vitro as subconfluent monolayers, and have confirmed a stimulatory effect of iodide on thyroidal TGF-β1 mRNA and peptide release. RNA extracted from TFCs maintained in the absence of iodide contained a 2·5 kb transcript which hybridized specifically with a cDNA probe for human TGF-β1, and which showed an approximate doubling in intensity in cells exposed to 10 μmol NaI/l. In the presence of the anti-thyroid thionamide drug methimazole (MMI; 1 mmol/l), the action of iodide on TGF-β1 mRNA was attenuated, although MMI alone had no effect on the control level of TGF-β1 mRNA. The TGF-β1 peptide content of TFC-conditioned media (TFC-CM) was assessed using the fetal mink lung cell line Mv1 Lu, in which activated TGF-β1 specifically suppresses trichloroacetic acid-precipitable [methyl-3H]thymidine incorporation. Newly conditioned TFC-CM stimulated [methyl-3H]thymidine incorporation into Mv1Lu cells, but after heat treatment to inactivate growth stimulators and activate the latent TGF-β1 component this medium inhibited [methyl-3H]thymidine incorporation. This inhibitory effect was prevented by immunoadsorption of TFC-CM with a TGF-β1-neutralizing antiserum, confirming the specificity of the inhibitory response. The inhibitory activity of TFC-CM was increased when the TFCs were preincubated with 10 μmol NaI/l, and lost when TFCs were exposed to MMI. In conclusion, TFCs produce TGF-β1 mRNA and TGF-β1 peptide, which are both increased by iodide treatment in vitro. The anti-thyroid effects of MMI may, at least in part, be mediated by a decrease in TFC-derived TGF-β1 production.

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Hanson, Heather, Ann Tokay Harrington, and Kim Nixon-Cave. "Implementing Treatment Frequency and Duration Guidelines in a Hospital-Based Pediatric Outpatient Setting: Administrative Case Report." Physical Therapy 95, no. 4 (April 1, 2015): 678–84. http://dx.doi.org/10.2522/ptj.20130360.

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Background and Purpose Determining treatment frequency and duration of physical therapist services is an important component of outpatient pediatric physical therapist practice, yet there is little research available to inform these decisions. Treatment frequency guidelines (TFG) can assist decision making in guiding pediatric physical therapy. The purpose of this project was to examine the feasibility and application of implementing TFG in hospital-based pediatric outpatient physical therapy. Project Description Previously developed TFG were modified for use in our pediatric outpatient physical therapy department to include duration and were referred to as treatment frequency and duration guidelines (TFDG). In order to successfully implement the TFDG, there were 2 phases to the project. In phase 1, the staff were provided the guidelines and procedures in a staff meeting and via email using a PowerPoint presentation. Phase 2 was initiated due to the poor response of the staff in implementing the guidelines in their practice after phase 1. The format was changed to include formal re-education via small-group and one-on-one education sessions (phase 2). Chart reviews were completed to assess therapists' adherence to using TFDG. Outcomes Therapists' adherence to use of TFDG increased following re-education: phase 1 (n=225 charts, 31% adherence) and phase 2 (n=197 charts, 90% adherence). Discussion Treatment frequency and duration guidelines may assist in guiding frequency and duration decisions in pediatric physical therapy. Education via in-person meetings may improve adherence among staff.

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Abe, Koji, Nobuki Terada, and Toshiyasu Nakamura. "Cine MRI of the Triangular Fibrocartilage Complex during Radial–Ulnar Deviation." Journal of Wrist Surgery 07, no. 04 (August 15, 2018): 274–80. http://dx.doi.org/10.1055/s-0038-1668542.

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Purpose Changes in the shape of the triangular fibrocartilage complex (TFCC) during radial–ulnar deviation were studied using “cine-mode” magnetic resonance imaging (MRI) in 10 right wrists of healthy volunteers, 5 wrists of TFCC tear, and 5 wrists of ulnar styloid nonunion. Subjects and Methods The wrist was fixed in a custom acrylic device, which only allows radial and ulnar deviation. Coronal MR images of nine radial–ulnar deviated positions (every 5 degree from 15 degrees radial deviation to 25 degrees ulnar deviation) were obtained in volunteers and patients. Cine-mode MRI was assembled and was output to MPEG video to observe. Results Cine MRI demonstrated the ulnar side of the TFCC was elongated by average 15 mm in 15 degrees of radial deviation and shortened by average 8 mm in 25 degrees of ulnar deviation in all normal TFCC subjects. Distal portion of the triangular fibrocartilage (TFC) was compressed during radial–ulnar deviation in 10 healthy volunteers and in 3 patients, but proximal portion of the TFC was stable throughout the motion. In contrast, the wavy deformities on the disc in ulnar deviation were observed in three patients with horizontal tear inside the TFCC. In nonunion of the ulnar styloid process, the fragment was snapped in maximum ulnar deviated position or elongation of the space between the styloid fragment and ulna was seen. Conclusion This study indicated normal and abnormal changes in the shape of the TFCC during radial–ulnar deviation motion on cine MRI. The abnormal dynamic changes of the TFCC may be seen in ulnar deviated position in patients, which are related to positive ulnocarpal stress test with the wrist forced ulnar deviated.

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Lu, Guanji, Tao Ji, Binbin Zhang, Yu Ma, and Cong Liao. "Influence Factors and Prediction Model of Bond Strength of Tunnel Fireproof Coating under Freeze–Thaw Cycles." Materials 14, no. 6 (March 22, 2021): 1544. http://dx.doi.org/10.3390/ma14061544.

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The freeze–thaw resistant performance of a tunnel fireproof coating (TFC) has an important impact on bonding property and durability. The influence of redispersible emulsion powder, polypropylene fiber and air-entraining agent on TFCs was studied. Transverse fundamental frequency and ultrasonic sound velocity were used to evaluate the damage degree of TFC, and the mechanism was revealed by SEM and pore structure. The results show that the most beneficial effect on bond strength of TFC is redispersible emulsion powder, followed by air-entraining agent, and then polypropylene fiber. After freeze–thaw cycles, the cumulative pore volume of micropores in the TFC increases obviously, while the porosity of macropores does not change significantly. A prediction model was proposed, which can calculate the bond strength from the damage degree of TFC under freeze–thaw cycles. The achievement can promote the application of TFC in cold regions.

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Guo, Ming. "Research progress of follicular cytotoxic T cells in HIV infection." Infection International 6, no. 3 (April 10, 2018): 83–87. http://dx.doi.org/10.2478/ii-2018-0006.

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Abstract Recently, a new type of CD8+ T-cell subset, namely, the chemokine (C-X-C motif) receptor 5 (CXCR5+) cluster of differentiation (CD8+) T-cell subset (also called the follicular cytotoxic T-cell (TFC) subgroup), has been discovered around B-cell follicles. The discovery has aroused widespread interest. However, the processes and mechanisms of TFCs taking part in the immune response of the germinal center and their specific roles must still be clearly identified. This article reviews domestic and foreign studies on factors regulating the phenotype, physiological functions, maturity, and differentiation of TFCs and roles and clinical significance of these cells in HIV infection. This review has shown good application prospects for TFCs. The author believes that further studies on TFCs can provide another tool for cytotherapy to control or cure chronic viral infections or tumors.

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Hitchon, Patrick W., Vijay Goel, Thomas Rogge, Andrew Dooris, John Drake, and James Torner. "Spinal stability with anterior or posterior Ray threaded fusion cages." Journal of Neurosurgery: Spine 93, no. 1 (July 2000): 102–8. http://dx.doi.org/10.3171/spi.2000.93.1.0102.

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Object. The authors conducted a study to determine if the rigidity supplied to the spine by posterior placement of the Ray threaded fusion cage (TFC) is further enhanced by the placement of pedicle screws and, additionally, if bilateral anteriorly placed TFCs render the spine more rigid than a single anteriorly placed TFC. Methods. Ten human cadaveric spinal specimens (L2—S1) were affixed within a testing frame. Loads of 1.5, 3, 4.5, and 6 Nm were applied to the spine in six degrees of freedom: flexion—extension, right and left lateral bending, and right and left axial rotation. Motion in an x, y, and z cartesian axis system was tracked using dual video cameras following light-emitting diodes attached to the spine and base plate. Load testing of the spines was performed in the intact mode, following which the spinal segments were randomized to receive anterior or posterior instrumentation. In five spine specimens we performed posterior discectomy, posterior lumbar interbody fusion (PLIF) with placment of femoral rings and pedicle screws, PLIF with bilateral TFCs, and bilateral TFCs with pedicle screws. Five other spines underwent anterior-approach discectomy, followed by implantation of a unilateral cage and bilateral cages. Load testing was performed after each step. Conclusion. Spines in which PLIF with pedicle screws and TFCs with pedicle screws were placed were more rigid than after discectomy in all directions of motion except flexion. Anterior discectomy provided significantly (p ≤ 0.05) less stability in left and right axial rotation than the intact spines and following posterior discectomy. Following anterior implantation of bilateral TFCs, spines were significantly more rigid than after discectomy in all directions except extension.

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Baggley, C. R., and M. G. Read. "Investigation of a thermo-fluidic exchange pump in trilateral flash and organic Rankine cycles / trans. from Engl. M. A. Fedorova." Omsk Scientific Bulletin. Series Aviation-Rocket and Power Engineering 4, no. 4 (2020): 66–74. http://dx.doi.org/10.25206/2588-0373-2020-4-4-66-74.

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It is well known that large amounts of energy loss occurs at low temperature states in a wide range of industrial processes., The recovery and reuse of this energy is at the forefront of increasing the overall efficiencies of industrial systems. The aim of this paper is to investigate the effectiveness of using a Thermo-Fluidic Exchange (TFE) pump at low temperature conditions in both a SaturatedVapour Organic Rankine Cycle (SORC) and a Trilateral Flash Cycle (TFC). For some low temperature applications, TFCs have been shown to achieve higher net power output than conventional SORCs, due to their ability to extract more heat from the source fluid. This is the subject of current research as a result of advancements made in the design of positive displacement machines for operation as twophase expanders. Conventional turbines cannot be used for TFCs as they must operate in the vapour phase. One drawback of the TFC is the higher working fluid mass flow rate required. Depending on the scale of the system, this can potentially cause difficulties with pump selection. A TFE pump uses heat input to the system to increase the pressure and temperature of the working fluid, rather than the work input in a standard mechanical pump. This paper compares the net power output achievable using both mechanical and TFE pumps with SORC and TFC systems. The results suggest that the TFE pump could be a viable option for TFC systems

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Szromek, Adam R., Bartłomiej Walas, and Zygmunt Kruczek. "The Willingness of Tourism-Friendly Cities’ Representatives to Share Innovative Solutions in the Form of Open Innovations." Journal of Open Innovation: Technology, Market, and Complexity 8, no. 3 (June 25, 2022): 112. http://dx.doi.org/10.3390/joitmc8030112.

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The tendency of enterprises to use open innovations can be seen in the literature in many areas of research and practical application. However, the use of the concept of open innovation in local administration entities is less noticeable. The research gap in this area prompts the authors to examine such a tendency among city representatives in the example of the Tourism Friendly Cities (TFC) group. TFC is a group of nine tourism destinations that are also European cities struggling with the impact of modern tourism. They take part in the URBACT program under the European Territorial Cooperation program. The goal of the article is to identify the basic problems of TFCs with the impact of the COVID-19 pandemic and to assess the propensity of TFC representatives to transfer innovative solutions in the form of open innovation. The article presents findings based on interviews with 104 experts from these cities, consisting of representatives of the public and private sectors. Research results indicate that the key problems of modern tourism in TFCs include constraints related to the lack of parking spaces, high rents and high prices of land, and short-term rental housing. The experts recommend measures to increase resilience and competitiveness initiated by business owners and at the initiative of the local administration. Key tools in this regard include and local community communication and engagement, creating attractions that benefit both residents and visitors, and measuring and monitoring tourism. In all, 92.8% of the experts believe that the right solution for the development of methods and tools for stakeholder cooperation in TFCs is to share the developed solutions in the form of open innovation.

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Cowin, A. J., E. L. Heaton, S. H. Cheshire, and S. P. Bidey. "The proliferative responses of porcine thyroid follicular cells to epidermal growth factor and thyrotrophin reflect the autocrine production of transforming growth factor-β1." Journal of Endocrinology 148, no. 1 (January 1996): 87–94. http://dx.doi.org/10.1677/joe.0.1480087.

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Abstract The present study has investigated an involvement of autocrine transforming growth factor-β1 (TGF-β1) in regulating the proliferative response of porcine thyroid follicular cells (TFCs) to epidermal growth factor (EGF) and TSH. Primary monolayer TFC cultures exposed to EGF over the range 0–0·4 nmol/l showed a dose-dependent increase in [methyl-3H]thymidine incorporation, whereas higher EGF doses were associated with a reduction in the level of [methyl-3 H]thymidine incorporation. TGF-β immunoneutralisation had little effect on the stimulatory action of low EGF doses, but led to an increase in [methyl-3H]thymidine incorporation at higher EGF levels. In TFC cultures exposed to TSH, the level of [methyl-3H]thymidine incorporation attained at a dose of 1 U TSH/1 was enhanced in the presence of TGF-β1 antiserum, although the similar stimulatory effect of 8-bromo cAMP was unaffected. Treatment of TFCs with phorbol 12-myristate 13-acetate (8 nmol/l) to activate protein kinase C (PKC) led to an enhanced incorporation of [methyl-3H]thymidine which was increased further after neutralisation of endogenous TGF-β1. While confirming, therefore, a role for autocrine TGF-β1 in maintaining control of TFC DNA synthesis in vitro, these findings provide evidence that an increase in the availability of autocrine TGF-β1 effected by EGF and TSH may play an instrumental role in limiting the cellular hyperplasia induced by these factors within the thyroid follicular microenvironment. Moreover, the present data also suggest that the availability of active autocrine TGF-β1 to TFCs under such conditions may be dependent upon a PKC-mediated mechanism. Journal of Endocrinology (1996) 148, 87–94

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Abid, Salah, and Russul K. Abdulrazak. "[0, 1] truncated fréchet-gamma and inverted gam-ma distributions." International Journal of Scientific World 5, no. 2 (October 30, 2017): 151. http://dx.doi.org/10.14419/ijsw.v5i2.8363.

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In this paper, we introduce a new family of continuous distributions based on [0, 1]] truncated Fréchet distribution. [0, 1]] Truncated Fréchet Gamma ([0, 1]] TFG) and truncated Fréchet inverted Gamma ([0, 1]] TFIG) distributions are discussed as special cases. The cumulative distribution function, the rth moment, the mean, the variance, the skewness, the kurtosis, the mode, the median, the characteristic function, the reliability function and the hazard rate function are obtained for the distributions under consideration. It is well known that an item fails when a stress to which it is subjected exceeds the corresponding strength. In this sense, strength can be viewed as "resistance to failure." Good design practice is such that the strength is always greater than the expected stress. The safety factor can be defined in terms of strength and stress as strength/stress. So, the [0, 1]] TFG strength-stress and the [0, 1]] TFIG strength-stress models with different parameters will be derived here. The Shannon entropy and Relative entropy will be derived also.

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Dubrov, V. E., D. A. Grechukhin, D. V. Davydov, L. K. Brizhan, and G. F. Gubaidullina. "Impact of TFCC injuries combined with distal radius fractures on long-term results of hand function: a comparative study." Genij Ortopedii 28, no. 4 (August 2022): 469–74. http://dx.doi.org/10.18019/1028-4427-2022-28-4-469-474.

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Introduction Fractures of the distal metaepipheseal fractures of the radius (DMER) have a leading place in the overall structure of upper limb injuries. DMER fractures are frequently associated with soft- tissue injuries of the wrist joint, and namely, the triangular fibrocartilage complex (TFCC). The additional use of arthroscopy of the wrist joint in the treatment of patients with a DMER fractiures reduces the duration of recovery of patients and improves the result of their treatment. The aim of the study was to determine the effect of arthroscopic surgical treatment of TFCC injuries during bone osteosynthesis for DMER fractures on the functions of the upper extremities (extension/flexion of the hand, hand grip strength, pronation/supination of the forearm, DASH index). Materials and methods The study included 68 patients with DMER fractures, who were divided into 2 groups, depending on the treatment of the fracture. After reduction and osteosynthesis, all patients underwent arthroscopy of the wrist joint. If TFCC injury was detected, either a debridement or a TFCC suture was performed. Results TFCC injury was detected in 61.7 % (n = 42). Debridement was performed in 42.9 % (n = 18); suture using the inside-out technique was performed in 47.6 % (n = 20); one patient underwent reinsertion. After 6 months, the function of flexion and extension of the hand was significantly worse in patients with combined TFCC and DMER injuries, but after 12 months, the indicators were similar. The strength of the hand grip and the rotational function of the forearm did not differ between the subgroups. The subjective assessment of DASH after 6 months was worse in the group with TFCC injury, but after 12 months the results were similar. Conclusion Surgical treatment of TFCС injury in intraarticular fractures of the distal radius contributes to the restoration of the upper limb function to a premorbid level 12 months after surgical treatment.

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Lee, You Mie, Ji-Hak Jeong, Hyunha Jang, and Jihye You. "Abstract 6160: Tie2-mediated AMPK activation by ferritin-based protein C nanoparticles inhibits advanced prostate cancer development through induction of vasodilation." Cancer Research 82, no. 12_Supplement (June 15, 2022): 6160. http://dx.doi.org/10.1158/1538-7445.am2022-6160.

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Abstract Prostate cancer (PCa) is one of the most common malignancies and the second-leading cause of cancer-related mortality in men in Western countries. Androgen deprivation therapy (ADT) is an initial systemic therapy for advanced PCa, but almost all cancer eventually becomes castration resistant. Recently, we introduced ferritin-based protein C nanoparticles (PCNs), known as TFG and TFMG, which enhance normalization of the tumor vasculature. However, the exact underlying mechanism how PCNs induces AMP-activated protein kinase (AMPK) activation and anti-tumor activity in castration-resistant prostate cancer (CRPC) remains unknown. Here, we investigated the role of PCNs for CRPC development in endothelial cells. We found that TFMG inhibits prostate cancer castration resistance by activating AMPK through the Tie2-mediated signaling pathway. TFMG treatment increased AMPK phosphorylation at Thr172 and acetyl-CoA carboxylase (ACC) at Ser79 in EA.hy926 cells. TFMG treatment also significantly increased the phosphorylation of endothelial nitric oxide synthase (eNOS) with inducing nitric oxide (NO) production in EA.hy926 cells. In addition, TFMG treatment induced the vasodilatory effect in isolated rat mesenteric resistance arteries (MRAs), which was blocked by NO synthase inhibitor L-NAME. Interestingly, these effects were all abolished by pretreatment with Compound C (an AMPK inhibitor), rebastinib (selective Tie2 Inhibitor), AMPK knockdown using siRNA, or dominant negative AMPKα recombinant adenovirus. Finally, we found that TFMG functionally abrogates CRPC development in mouse model. In summary, TFMG exerted vasodilatation through activating Tie2/AMPK/eNOS signaling in endothelial cells, which leads to the overcoming vasoconstriction induced ADT. This study provides the potential value of TFMG in vasodilation of blood vessels leading suppression of CRPC development. Citation Format: You Mie Lee, Ji-Hak Jeong, Hyunha Jang, Jihye You. Tie2-mediated AMPK activation by ferritin-based protein C nanoparticles inhibits advanced prostate cancer development through induction of vasodilation [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 6160.

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Mohammed, Shabin, Haya Nassrullah, Jamaliah Aburabie, and Raed Hashaikeh. "Fabrication of Thin Film Composite Membranes on Nanozeolite Modified Support Layer for Tailored Nanofiltration Performance." Membranes 12, no. 10 (September 27, 2022): 940. http://dx.doi.org/10.3390/membranes12100940.

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Thin-film composite (TFC) structure has been widely employed in polymeric membrane fabrication to achieve superior performance for desalination and water treatment. In particular, TFC membranes with a thin active polyamide (PA) selective layer are proven to offer improved permeability without compromising salt rejection. Several modifications to TFCs have been proposed over the years to enhance their performance by altering the selective, intermediate, or support layer. This study proposes the modification of the membrane support using nanozeolites prepared by a unique ball milling technique for tailoring the nanofiltration performance. TFC membranes were fabricated by the interfacial polymerization of Piperazine (PIP) and 1,3,5-Benzenetricarbonyl trichloride (TMC) on Polysulfone (PSf) supports modified with nanozeolites. The nanozeolite concentration in the casting solution varied from 0 to 0.2%. Supports prepared with different nanozeolite concentrations resulted in varied hydrophilicity, porosity, and permeability. Results showed that optimum membrane performance was obtained for supports modified with 0.1% nanozeolites where pure water permeance of 17.1 ± 2.1 Lm−2 h−1 bar−1 was observed with a salt rejection of 11.47%, 33.84%, 94%, and 95.1% for NaCl, MgCl2, MgSO4, and Na2SO4 respectively.

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Watson, P. F., A. P. Pickerill, R. Davies, and A. P. Weetman. "Semi-quantitative analysis of interleukin-1α, interleukin-6 and interleukin-8 mRNA expression by human thyrocytes." Journal of Molecular Endocrinology 15, no. 1 (August 1995): 11–21. http://dx.doi.org/10.1677/jme.0.0150011.

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ABSTRACT It has been suggested that the thyroid itself may contribute to the inflammatory process observed in autoimmune thyroiditis by releasing the cytokines interleukin-1α (IL-1α), interleukin-6 (IL-6) and interleukin-8 (IL-8), but studies of cytokine gene expression in thyrocytes have been limited and conflicting. A semi-quantitative reverse transcription-PCR technique has been used to investigate the expression of IL-1α, IL-6 and IL-8 mRNA in the human thyroid cell line HTori3 and in cultures of primary human thyroid follicular cells (TFCs). Cytokine mRNA levels were examined over a 24-h period, and the modulatory effects of exogenous IL-1α, interferon-γ (IFN-γ) and TSH investigated. Basal expression of IL-1α, IL-6 and IL-8 mRNA was detected in HTori3 and primary TFC cultures. Stimulation with IL-1 (10 U/ml) for 12 h produced an increase in the level of IL-1α mRNA in both primary TFC and HTori3 cultures. IL-6 and IL-8 mRNA levels were increased by the addition of IL-1 in both cell types, and this effect was detected throughout the 24-h time-course. IFN-γ (100 U/ml) had no significant effect on cytokine gene expression. A higher concentration of IFN-γ (500 U/ml) had no significant effect on the expression of IL-1α or IL-8 but produced an increase in the level of IL-6 mRNA in primary cultures and in HTori3 cells. Addition of TSH (1 mU/ml) produced an increase in the level of IL-1α mRNA in primary TFC and HTori3 cells, at 12 and 24 h. TSH had no significant effect on the expression of IL-6 or IL-8 mRNA. These results demonstrate that human TFCs constitutively express IL-1α, IL-6 and IL-8 mRNA and that this expression can be modulated by IL-1, IFN-γ and TSH.

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Hoffmeister, Ellen. "TFCC Injuries." Lippincott's Bone and Joint Newsletter 15, no. 3 (March 2009): 25. http://dx.doi.org/10.1097/01.bonej.0000346726.59288.09.

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Beyermann, K., H. Krimmer, and U. Lanz. "TFCC-Läsionen." Der Orthopäde 28, no. 10 (1999): 891. http://dx.doi.org/10.1007/s001320050481.

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Longo, Mariagiulia, Marcello Monteleone, Elisa Esposito, Alessio Fuoco, Elena Tocci, Maria-Chiara Ferrari, Bibiana Comesaña-Gándara, Richard Malpass-Evans, Neil B. McKeown, and Johannes C. Jansen. "Thin Film Composite Membranes Based on the Polymer of Intrinsic Microporosity PIM-EA(Me2)-TB Blended with Matrimid®5218." Membranes 12, no. 9 (September 13, 2022): 881. http://dx.doi.org/10.3390/membranes12090881.

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In this work, thin film composite (TFC) membranes were fabricated with the selective layer based on a blend of polyimide Matrimid®5218 and polymer of intrinsic microporosity (PIM) composed of Tröger’s base, TB, and dimethylethanoanthracene units, PIM-EA(Me2)-TB. The TFCs were prepared with different ratios of the two polymers and the effect of the PIM content in the blend of the gas transport properties was studied for pure He, H2, O2, N2, CH4, and CO2 using the well-known time lag method. The prepared TFC membranes were further characterized by IR spectroscopy and scanning electron microscopy (SEM). The role of the support properties for the TFC membrane preparation was analysed for four different commercial porous supports (Nanostone Water PV 350, Vladipor Fluoroplast 50, Synder PAN 30 kDa, and Sulzer PAN UF). The Sulzer PAN UF support with a relatively small pore size favoured the formation of a defect-free dense layer. All the TFC membranes supported on Sulzer PAN UF presented a synergistic enhancement in CO2 permeance, and CO2/CH4 and CO2/N2 ideal selectivity. The permeance increased about two orders of magnitude with respect to neat Matrimid, up to ca. 100 GPU, the ideal CO2/CH4 selectivity increased from approximately 10 to 14, and the CO2/N2 selectivity from approximately 20 to 26 compared to the thick dense reference membrane of PIM-EA(Me2)-TB. The TFC membranes exhibited lower CO2 permeances than expected on the basis of their thickness—most likely due to enhanced aging of thin films and to the low surface porosity of the support membrane, but a higher selectivity for the gas pairs CO2/N2, CO2/CH4, O2/N2, and H2/N2.

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Arrebola, Rosalía, Nathalie Manaud, Sophie Rozenfeld, Marie-Claude Marsolier, Olivier Lefebvre, Christophe Carles, Pierre Thuriaux, Christine Conesa, and André Sentenac. "τ91, an Essential Subunit of Yeast Transcription Factor IIIC, Cooperates with τ138 in DNA Binding." Molecular and Cellular Biology 18, no. 1 (January 1, 1998): 1–9. http://dx.doi.org/10.1128/mcb.18.1.1.

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ABSTRACT Transcription factor IIIC (TFIIIC) (or τ) is a large multisubunit and multifunctional factor required for transcription of all class III genes in Saccharomyces cerevisiae. It is responsible for promoter recognition and TFIIIB assembly. We report here the cloning and characterization of TFC6, an essential gene encoding the 91-kDa polypeptide, τ91, present in affinity-purified TFIIIC. τ91 has a predicted molecular mass of 74 kDa. It harbors a central cluster of His and Cys residues and has basic and acidic amino acid regions, but it shows no specific similarity to known proteins or predicted open reading frames. The TFIIIC subunit status of τ91 was established by the following biochemical and genetic evidence. Antibodies to τ91 bound TFIIIC-DNA complexes in gel shift assays; in vivo, a B block-deficient U6 RNA gene (SNR6) harboring GAL4 binding sites was reactivated by fusing the GAL4 DNA binding domain to τ91; and a point mutation in TFC6 (τ91-E330K) was found to suppress the thermosensitive phenotype of a tfc3-G349Emutant affected in the B block binding subunit (τ138). The suppressor mutation alleviated the DNA binding and transcription defects of mutant TFIIIC in vitro. These results indicated that τ91 cooperates with τ138 for DNA binding. Recombinant τ91 by itself did not interact with a tRNA gene, although it showed a strong affinity for single-stranded DNA.

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Elhady, Sarah, Mohamed Bassyouni, Ramadan A. Mansour, Medhat H. Elzahar, Shereen Abdel-Hamid, Yasser Elhenawy, and Mamdou Y. Saleh. "Oily Wastewater Treatment Using Polyamide Thin Film Composite Membrane Technology." Membranes 10, no. 5 (April 28, 2020): 84. http://dx.doi.org/10.3390/membranes10050084.

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In this study, polyamide (PA) thin film composite (TFC) reverse osmosis (RO) membrane filtration was used in edible oil wastewater emulsion treatment. The PA-TFC membrane was characterized using mechanical, thermal, chemical, and physical tests. Surface morphology and cross-sections of TFCs were characterized using SEM. The effects of edible oil concentrations, average droplets size, and contact angle on separation efficiency and flux were studied in detail. Purification performance was enhanced using activated carbon as a pre-treatment unit. The performance of the RO unit was assessed by chemical oxygen demand (COD) removal and permeate flux. Oil concentration in wastewater varied between 3000 mg/L and 6000 mg/L. Oily wastewater showed a higher contact angle (62.9°) than de-ionized water (33°). Experimental results showed that the presence of activated carbon increases the permeation COD removal from 94% to 99%. The RO membrane filtration coupled with an activated carbon unit of oily wastewater is a convenient hybrid technique for removal of high-concentration edible oil wastewater emulsion up to 99%. Using activated carbon as an adsorption pre-treatment unit improved the permeate flux from 34 L/m2hr to 75 L/m2hr.

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Doarn, Michael C., and Robert W. Wysocki. "Acute TFCC Injury." Operative Techniques in Sports Medicine 24, no. 2 (June 2016): 123–25. http://dx.doi.org/10.1053/j.otsm.2016.02.001.

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Meier, R., R. Schmitt, G. Christopoulos, and H. Krimmer. "TFCC-L�sionen." Der Unfallchirurg 106, no. 3 (March 1, 2003): 190–94. http://dx.doi.org/10.1007/s00113-002-0505-5.

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Yang, S., and Y. Gohar. "TFCX Shielding Optimization." Fusion Technology 8, no. 1P2A (July 1985): 1012–19. http://dx.doi.org/10.13182/fst85-a40166.

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Hu, Xiao-Fang, Zong-Bao Ding, Yue Chen, Jiang-Fu Luo, Jian-Min He, and Tian-Peng Yin. "Comparative study on the antioxidant activities of ten common flower teas from China." Open Chemistry 17, no. 1 (October 16, 2019): 841–48. http://dx.doi.org/10.1515/chem-2019-0091.

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AbstractFlower teas are widely consumed across the world because of their beneficial health effects. The antioxidant activities of methanol extracts from ten common flower teas in China were evaluated using four antioxidant assays. The total phenolic (TPCs) and total flavonoid contents (TFCs) were also investigated. Most of these flower teas exhibited potent antioxidant effects, of which rosae rugosae flos exerted the strongest antioxidant effects in four assays. Rosae rugosae flos also exerted the highest TPC, while fragrans showed the highest TFC. Correction analysis indicated that phenolics play a key role in the antioxidant effect of flower teas, while flavonoids were poorly correlated with antioxidant activity. The results supported the consumption of flower teas as functional foods and their application as sources of natural antioxidants in the food industry.

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Yoshida, Ryo, Moroe Beppu, Syoji Ishii, and Kazuaki Hirata. "ANATOMICAL STUDY OF THE DISTAL RADIOULNAR JOINT: DEGENERATIVE CHANGES AND MORPHOLOGICAL MEASUREMENT." Hand Surgery 04, no. 02 (December 1999): 109–15. http://dx.doi.org/10.1142/s0218810499000356.

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A study of the degenerative changes in the distal radioulnar joint compared with morphological measurement of that joint using 91 joints of the hand from 51 systemic anatomy cadavers was conducted. X-ray images of the joints of the hand were taken followed by measurement of radial inclination, ulnar variance, volar tilt, sigmoid notch inclination and ulnar seat inclination. Macroscopic observations of the ulnar notch of the radius and surface of the distal radioulnar joint of the ulnar head were made by dividing them into six and nine areas, respectively. These were then used to classify the degree of cartilage degeneration. In addition, the status of the triangular fibrocartilage complex (TFCC) was also observed. Arthropathic changes of the distal radioulnar joint were associated with factors including TFC degeneration and UV(+), SNI(-) and USI(+).

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Wiffen, F. W. "Materials engineering for TFCX." Journal of Nuclear Materials 133-134 (August 1985): 32–38. http://dx.doi.org/10.1016/0022-3115(85)90108-4.

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Orihuela-Rivera, Carmen Adela, Gabriela Cristina Chire, and María Rosario Calixto-Cotos. "Antioxidants properties of chocolates sold in Peru." Acta Agronómica 67, no. 4 (October 1, 2018): 479–85. http://dx.doi.org/10.15446/acag.v67n4.71357.

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The goals of this paper were to evaluate total polyphenol content (TPC), total flavonoid content (TFC), anti-oxidant capacity (AC) and reducing power (RP) of eight dark chocolates that are sold in Peru. Imported and domestic chocolate samples containing between 50% and 74% cacao were defatted. Defatted chocolate (DCh) was separated and treated to extract phenolic compounds. The TPC and AC were determined by using the Folin-Ciocalteu reagent and two in vitro models based on the free-radical capturing capacity DPPH and ABTS. The RP was evaluated by using the potassium pherricyanide method; in the TFCs assessments, catechin was used as the standard. Chocolate TPC varied between 1.69 ± 0.02 and 5.39 ± 0.17 mg gallic acid/g chocolate and AC (DPPH-IC50) varied between 52.97 ± 1.77 and 158.67 ± 2.04 μg/ml extract, and by means of ABTS the values were between 12.01 ± 0.18 and 32.74 ± 0.49 μmol TEAC/g chocolate. Chocolates with 71% and 72% cacao showed a greater antioxidant capacity, which was confirmed by the RP test. Chocolates showed different levels of TPC, TFC, AC and RP, depended on a large degree of the cacao percentage. However, in some cases, there was no direct relationship among results, most likely due to different technological and thermal processes as well as different biological nature of cacao beans.

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Ostrov, Barbara E. "TFC Calcification?" Journal of Clinical Rheumatology 18, no. 8 (December 2012): 452. http://dx.doi.org/10.1097/rhu.0b013e31827af54a.

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Marques Junior, Edilson, Felipe Menine, Rodrigo Monte Lorenzoni, Taís Cristina Bastos Soares, and Fábio Luiz De Oliveira. "SELEÇÃO DE MÉTODOS DE ARMAZENAMENTO DE TECIDOS FOLIARES PARA EXTRAÇÃO DE DNA DE YACON." Revista Univap 22, no. 40 (April 24, 2017): 797. http://dx.doi.org/10.18066/revistaunivap.v22i40.1605.

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A yacon vem se destacando devido aos efeitos promissórios para a saúde humana, gerando a necessidade de mais pesquisas sobre a espécie. Sendo assim, o objetivo da pesquisa foi avaliar diferentes formas de armazenamento de folhas de yacon para extração de DNA com qualidade para realização de análises moleculares. Foram testadas cinco formas de armazenamento dos tecidos foliares, com dez amostras por tratamento, sendo elas: Tecido foliar fresco (TFF), Tecido foliar congelado (TFC), Tecido foliar armazenado com sílica em geladeira (TFSG), Tecido foliar mantido por cinco dias com sílica em temperatura ambiente (TFSTA) e Tecido foliar mantido por cinco dias sem sílica em temperatura ambiente (TFTA). Para extração de DNA, em todos os tratamentos, foi utilizado o protocolo proposto por Doyle e Doyle (1990) com modificações. Em todos os tratamentos foi obtido quantidade de DNA suficiente para realização de análises moleculares, sendo que o melhor resultado foi obtido pelo tratamento TFF com 331,24ng e o menor valor foi oriundo do tratamento TFTA com 42,98ng.

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Zlatanović, Snežana, Ana Kalušević, Darko Micić, Jovanka Laličić-Petronijević, Nikola Tomić, Sanja Ostojić, and Stanislava Gorjanović. "Functionality and Storability of Cookies Fortified at the Industrial Scale with up to 75% of Apple Pomace Flour Produced by Dehydration." Foods 8, no. 11 (November 8, 2019): 561. http://dx.doi.org/10.3390/foods8110561.

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Apple pomace flour (APF) with high content of dietary fibers (DF), total polyphenolics (TPCs) and flavonoids (TFCs) was produced at the industrial scale. Bulk and tapped density, swelling, water and oil holding capacity, solubility and hydration density of fine and coarse APF with average particle size 0.16 and 0.50 mm were compared. The effect of wheat flour substitution with 25%, 50% and 75% of fine and coarse APF was studied upon cookies production at the industrial scale and after one year of storage. Coarse APF performed better in respect to sensorial properties, content and retention of dietary compounds and antioxidant (AO) activity. The cookies with optimal share of coarse APF (50%) contained 21 g/100 g of DF and several times higher TPC, TFC as well as AO activity than control cookies, retained well health promoting compounds and maintained an intensely fruity aroma and crispy texture. They were acceptable for consumers according to the hedonic test.

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Osterman, A. Lee, and Robert G. Terrill. "Arthroscopic Treatment of TFCC Lesions." Hand Clinics 7, no. 2 (May 1991): 277–81. http://dx.doi.org/10.1016/s0749-0712(21)01077-5.

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Yumiya, Hiroyuki, Mikio Kizaki, and Hisao Asai. "Toyota Fuel Cell System (TFCS)." World Electric Vehicle Journal 7, no. 1 (March 27, 2015): 85–92. http://dx.doi.org/10.3390/wevj7010085.

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33

KALAINOV, DAVID M., and RANDALL W. CULP. "Arthroscopic Treatment of TFCC Tears." Techniques in Hand & Upper Extremity Surgery 1, no. 3 (September 1997): 175–82. http://dx.doi.org/10.1097/00130911-199709000-00004.

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34

Zachee, B., L. De Smet, and G. Fabry. "Arthroscopic suturing of TFCC lesions." Arthroscopy: The Journal of Arthroscopic & Related Surgery 9, no. 2 (April 1993): 242–43. http://dx.doi.org/10.1016/s0749-8063(05)80386-x.

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Harvey, Norah M., and Randall W. Culp. "Baseball Commentary “Traumatic TFCC Tear”." Hand Clinics 28, no. 3 (August 2012): 323–24. http://dx.doi.org/10.1016/j.hcl.2012.05.015.

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36

Weiglein, A. H., G. Windisch, H. Clement, and W. Grechenig. "Anatomie des ulnocarpalen Bandkomplexes (TFCC)." European Surgery 34, S3 (May 2002): 45–46. http://dx.doi.org/10.1007/bf02947690.

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37

Reilly, H. J., B. J. Merrill, and S. J. Piot. "Tritium safety issues for TFCX." International Journal of Applied Radiation and Isotopes 36, no. 7 (July 1985): 583. http://dx.doi.org/10.1016/0020-708x(85)90144-9.

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38

Schmidt, John A. "Summary Abstract: TFCX design studies." Journal of Vacuum Science & Technology A: Vacuum, Surfaces, and Films 3, no. 3 (May 1985): 1141–42. http://dx.doi.org/10.1116/1.573092.

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39

Beyermann, K., H. Krimmer, and U. Lanz. "TFCC lesions. Diagnosis and therapy." Der Orthopäde 28, no. 10 (October 1999): 891–98. http://dx.doi.org/10.1007/pl00003565.

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40

Jawed, Akram, Mohammed Tahir Ansari, and Vikas Gupta. "TFCC injuries: How we treat?" Journal of Clinical Orthopaedics and Trauma 11, no. 4 (July 2020): 570–79. http://dx.doi.org/10.1016/j.jcot.2020.06.001.

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41

Jiang Qi, 蒋奇, and 胡德波 Hu Debo. "A Comparative Study of Refractive Index Sensors Based on Bare TFBG and SPR-TFBG." Laser & Optoelectronics Progress 49, no. 8 (2012): 080602. http://dx.doi.org/10.3788/lop49.080602.

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Arimitsu, Sayuri, and Hisao Moritomo. "New TFCC Reconstructive Technique Using Ulnotriquetral Ligament for the Ulnar Foveal Tear of TFCC." Journal of Hand Surgery 43, no. 9 (September 2018): S27. http://dx.doi.org/10.1016/j.jhsa.2018.06.065.

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van der Vaart, Jelte, Lynn Bosmans, Hanneke Margo van Santen, Menno R. Vriens, and Hans Clevers. "Generation of Adult Stem Cell Derived Organoid Cultures From Thyroid Follicular Cells." Journal of the Endocrine Society 5, Supplement_1 (May 1, 2021): A850—A851. http://dx.doi.org/10.1210/jendso/bvab048.1736.

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Abstract The thyroid is essential for maintaining systemic homeostasis by regulating thyroid hormone concentrations in the bloodstream. Due to the limited number of representative model systems, there is limited understanding of fundamental thyroid biology as well as thyroid carcinogenesis. To fill the caveats in the understanding of thyroid cell biology, we aimed to develop an adult stem cell-derived three-dimensional (3D) organoid culture system using murine and human thyroid follicular cells (TFCs). We have succeeded to grow such an organoid culture system that harbours the complete machinery of hormone production visualised by the presence of colloid in the lumen and essential transporters and enzymes in a polarised cell layer. Both the established murine as human thyroid organoids express canonical thyroid markers PAX8 and NKX2.1/TTF1. Moreover, the thyroid hormone precursor thyroglobulin is expressed in both cultures to similar levels as in tissue. Extensive characterisation furthermore identifies known and new biological insights in TFC subclassification, subcellular organisation and hormone production using state-of-the art techniques like single cell RNA sequencing, transmission electron microscopy and genome editing. These 3D in vitro cultures allow for a variety of thyroid-related studies including the progression of wild type cells towards cancer. Additionally, due to the success of generating patient-specific tumour organoids of primary differentiated thyroid carcinoma and metastasis, insights in drug resistance and metastases can be identified. In short, this newly developed organoid culture of murine and human wild type TFCs as well as tumour tissue opens up an extensive area of research that will help understand the drivers for growth and development of thyroid (cancer) cells and enable studies upon drug responsiveness.

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Tang, Peter, Keiji Fujio, Robert Strauch, Melvin Rosenwasser, and Taiichi Matsumoto. "The Optimal Suture Placement and Bone Tunnels for TFCC Repair: A Cadaveric Study." Journal of Wrist Surgery 07, no. 05 (June 26, 2018): 375–81. http://dx.doi.org/10.1055/s-0038-1661361.

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Background Transosseous repair of foveal detachment of the triangular fibrocartilage complex (TFCC) is effective for distal radioulnar joint stabilization. However, studies of the optimal foveal and TFCC suture positions are scant. Purpose The purpose of this study was to clarify the optimal TFCC suture position and bone tunnels for transosseous foveal repair. Materials and Methods Seven cadavers were utilized. The TFCC was incised at the foveal insertion and sutured at six locations (TFCCs 1–6) using inelastic sutures. Six osseous tunnels were created in the fovea (foveae 1–6). Fovea 2 is located at the center of the circle formed by the ulnar head overlooking the distal end of the ulna (theoretical center of rotation); fovea 5 is located 2 mm ulnar to fovea 2. TFCC 5 is at the ulnar apex of the TFCC disc; TFCC 4 is 2 mm dorsal to TFCC 5. TFCC 1 to 6 sutures were then placed through each of the six osseous tunnels, resulting in 36 combinations, which were individually tested. The forearm was placed in five positions between supination and pronation, and the degree of suture displacement was measured. The position with the least displacement indicated the isometric point of the TFCC and fovea. Results The mean distance of suture displacement was 2.4 ± 1.6 mm. Fovea 2, combined with any TFCC location, (0.7 ± 0.6 mm) and fovea group 5, combined with TFCC 4 location (0.8 ± 0.8) or with TFCC 5 location (0.9 ± 0.6) had statistically shorter suture displacements than any other fovea groups. Conclusion For TFCC transosseous repair, osseous tunnel position was more important than TFCC suture location.

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Ng, Alex W. H., Cina S. L. Tong, Esther H. Y. Hung, James F. Griffith, W. L. Tse, Clara W. Y. Wong, Michael C. K. Mak, and P. C. Ho. "Top-Ten Tips for Imaging the Triangular Fibrocartilaginous Complex." Seminars in Musculoskeletal Radiology 23, no. 04 (June 6, 2019): 436–43. http://dx.doi.org/10.1055/s-0039-1688715.

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AbstractThe triangular fibrocartilage complex (TFCC) is a crucial structure for both maintaining the stability of the distal radioulnar joint (DRUJ) and acting as a cushion for axial loading of the ulnocarpal joint. Injury to the TFCC can lead to early degeneration of the DRUJ and ulnocarpal joint, with resultant chronic wrist pain and weakness. The TFCC is a moderately complex structure with several attachments to the adjacent bony and cartilaginous structures. Familiarity with the anatomy of the TFCC is a prerequisite for identification of TFCC tears. Several pitfalls can occur while assessing the TFCC on magnetic resonance imaging (MRI) if one is not familiar with the MRI appearances. This article illustrates key tips for diagnosing TFCC tears on MRI.

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Thabet, Eman, Alaaeldin Yusuf, Doaa A. Abdelmonsif, Iman Nabil, Ghada Mourad, and Radwa A. Mehanna. "Extracellular vesicles miRNA-21: a potential therapeutic tool in premature ovarian dysfunction." Molecular Human Reproduction 26, no. 12 (October 13, 2020): 906–19. http://dx.doi.org/10.1093/molehr/gaaa068.

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Abstract Chemotherapy induces an irreversible premature ovarian dysfunction (POD). Amniotic fluid mesenchymal stem cells (AFMSCs) can rescue fertility; however, the notion that stem cells can rejuvenate follicles is highly controversial due to the predetermined ovarian reserve. This study aims to isolate AFMSC-derived extracellular vesicles (EVs) and investigate their abundancy for the anti-apoptotic miRNA-21 as a means of ovarian restoration. Female rats were divided into healthy controls and POD-induced groups. The POD induced groups were subdivided into three groups according to the therapies they received: placebo-treated POD, AFMSC and EVs groups. Rats were assessed for serum anti-Müllerian hormone (AMH) levels, ovarian caspase 3 and PTEN protein levels in the ovarian lysate. Total follicular counts (TFCs) were estimated from stained ovarian sections. Functional recovery was investigated through daily vaginal smears and mating trials. In vitro chemical transfection of the AFMSCs with selective miRNA-21 mimics/inhibitors followed by isolation of EVs for therapy was conducted in two additional groups. At the interval points studied, treatment with AFMSCs and EVs equally restored TFC, AMH levels, regular estrous cycles and fruitful conception, while it both diminished caspase 3 and PTEN levels. EVs carrying miRNA-21 mimics recapitulated the short-term effects. Placebo-treated POD or EVs carrying miRNA-21 inhibitors showed augmented ovarian follicular damage demonstrated the low AMH levels, TFC and high levels of PTEN and caspase 3. miRNA-21 allowed regeneration by modulating PTEN and caspase 3 apoptotic pathways. Our findings exemplify that EVs could serve as an innovative cell-free therapeutic tool functioning through their miRNA content and that miRNA-21 has a chief regenerative role through modulating PTEN and caspase 3 apoptotic pathways.

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Yan, Bingshan, Zhaoning Xu, Yanchao Chen, and Wangping Yin. "Prevalence of triangular fibrocartilage complex injuries in patients with distal radius fractures: a 3.0T magnetic resonance imaging study." Journal of International Medical Research 47, no. 8 (June 24, 2019): 3648–55. http://dx.doi.org/10.1177/0300060519856157.

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Objective This study was performed to determine the prevalence of triangular fibrocartilage complex (TFCC) injuries as shown by 3.0T magnetic resonance imaging (MRI) in patients with distal radius fractures. Methods In total, 57 patients with distal radius fractures underwent 3.0T MRI examinations to observe the incidence of TFCC injuries after manual reduction and cast fixation. The fracture type was categorized by the AO classiﬁcation, and the TFCC injury pattern was evaluated using the Palmer classiﬁcation. The correlation between the location of the TFCC injury and the distal radius fracture pattern, distal radioulnar joint instability, or ulnar styloid fracture was analyzed. Results Fifty-five TFCC injuries were diagnosed. There was no significant relationship between the TFCC injury pattern and the type of distal radius fracture, distal radioulnar joint instability, or ulnar styloid fracture. Conclusions This study revealed a high prevalence of TFCC injuries in patients with distal radius fractures. The 3.0T MRI examination helps to assess TFCC injuries in patients with distal radius fractures. Clinical Trial Registration ChiCTR1800017101.

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Selles, Caroline A., Philip N. d'Ailly, and Niels W. L. Schep. "Patient-Reported Outcomes following Arthroscopic Triangular Fibrocartilage Complex Repair." Journal of Wrist Surgery 09, no. 01 (November 26, 2019): 058–62. http://dx.doi.org/10.1055/s-0039-3400454.

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Abstract Background Triangular fibrocartilage complex (TFCC) injury is a common cause of ulnar-sided wrist pain, which may lead to serious physical impairments. Arthroscopic repair has benefits such as less soft tissue damage, greater surgical accuracy, and may lead to faster recovery than open repair. Objective The purpose of this study was to determine the functional outcome of patients with symptomatic TFCC injuries treated with arthroscopic debridement or repair. Patients and Methods A retrospective study of all consecutive patients with a TFCC injury treated arthroscopically was conducted. The primary outcome was the patient-rated wrist evaluation (PRWE) score. Secondary outcomes were, pain, operative findings, complications, and additional treatment. Results A total of 51 patients with a median follow-up of 16.5 months (interquartile range [IQR]: 13–25) were included. Injuries were treated with TFCC debridement (n = 25), TFCC ligament to capsule suturing (n = 10), TFCC debridement and ligament to capsule suturing (n = 7), TFCC debridement and synovectomy (n = 5), and TFCC foveal reinsertion with a suture anchor (n = 4). The median PRWE was 19.5 (IQR: 6–49). Complications occurred in three patients and in nine patients additional surgery was performed. Conclusion Arthroscopic treatment of TFCC lesions leads to satisfactory functional outcomes. Level of Evidence This is a Level IV study.

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Fujio, Keiji, Tatsuki Kashimoto, Michio Yamanaka, Kei Kondo, Tsuyoshi Yamazaki, Naoki Nishijima, and Saizou Teshima. "Synovial osteochondromatosis in the TFCC region." Orthopedics & Traumatology 45, no. 3 (1996): 852–54. http://dx.doi.org/10.5035/nishiseisai.45.852.

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Moloney, Maria, Simon Farnebo, and Lars Adolfsson. "20-Year outcome of TFCC repairs." Journal of Plastic Surgery and Hand Surgery 52, no. 3 (December 19, 2017): 193–97. http://dx.doi.org/10.1080/2000656x.2017.1415914.

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Journal articles on the topic 'TFCG'

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