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1

Udwadia, Farokh Erach. Tetanus. Bombay: Oxford University Press, 1994.

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2

DasGupta, Bibhuti R., ed. Botulinum and Tetanus Neurotoxins. Boston, MA: Springer US, 1993. http://dx.doi.org/10.1007/978-1-4757-9542-4.

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3

Zamula, Evelyn. Adults need tetanus shots, too. [Rockville, MD: Food and Drug Administration, 1996.

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4

International, Conference on Tetanus (8th 1987 Leningrad R. S. F. S. R. ). Eighth International Conference on Tetanus. Rome: Pythagora Press, 1989.

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5

Köhlke, Karin. Tetanus beim Pferd: Eine Literaturstudie. Hannover: [s.n.], 1985.

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6

Organization, Pan American Health. Neonatal tetanus elimination: Field guide. 2nd ed. Washington, D.C: Pan American Health Organization, Regional Office of the World Health Organization, 2005.

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7

Inmunización, Programa Ampliado de, Pan American Health Organization, and World Health Organization, eds. Neonatal tetanus elimination field guide. Washington, DC: The Organization, 1993.

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8

L, Simpson Lance, ed. Botulinum neurotoxin and tetanus toxin. San Diego: Academic Press, 1989.

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9

Afonso, Marilia Cabral Rodrigues Coelho. Estudo evolutivo dos doentes com tetano: Experiencia do serviço de medicina no periodo 1987-1989. Luanda: Hospital Josina Machel, Serviço de Medicina I, 1996.

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10

Nooy, Richard De. Six fang marks and a tetanus shot. Auckland Park, South Africa: Jacana, 2007.

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11

Soentoro, Soemarsih. Hubungan antara kesehatan mulut dengan penyakit tetanus. Surabaya: Lembaga Penelitian Universitas Airlangga, 1986.

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12

R, DasGupta Bibhuti, and International Conference on Botulinum, Tetanus Neurotoxins: Neurotransmission and Biomedical Aspects (1992 : Madison, Wis.), eds. Botulinum and tetanus neurotoxins: Neurotransmission and biomedical aspects. New York: Plenum Press, 1993.

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13

Koening, Michael Alan. Mortality reductions from measles and tetanus immunization: A review of the evidence. Washington, DC (1818 H St. NW, Washington 20433): World Bank, 1992.

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14

al-Bāb, Ḥaydar Dakk. Dirāsat ḥimāyat al-wildān min kizāz al-walīd: Wa-muʻaddal wafīyāt al-aṭfāl = Field survey on newborns protected against neonatal tetanus and infant mortality rate. Dimashq: Wizārat al-Ṣiḥḥah, Mudīrīyat al-Riʻāīyah al-Ṣiḥḥīyah al-Awwalīyah, 1993.

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15

Organization, Pan American Health, ed. Guía práctica para la eliminación del tétanos neonatal: Programa ampliado de inmunización, programa de salud maternoinfantil y población. Washington, D.C: Organización Panamericana de la Salud, Oficina Sanitaria Panamericana, Oficina Regional de la Organización Mundial de la Salud, 1993.

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16

UNICEF, ed. Accelerated tetanus toxoid programme in North West Frontier Province, Pakistan. Islamabad: UNICEF, 1988.

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17

O, Ndombi Isiye, Madema Simon, Botswana, World Health Organization, PolioPlus (Organization), and UNICEF, eds. Polio eradication and neonatal tetanus elimination: The status and plans. [Gaborone]: Republic of Botswana, 1991.

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18

Dow, William H. Death, tetanus and aerobics: The evaluation of disease-specific health interventions. London: Centre for Economic Policy Research, 1995.

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19

World Health Organization (WHO). Expanded programme on immunization: Neonatal tetanus : immunize all women of childbearing age. Geneva: World Health Organization, 1988.

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20

Great Britain. Department of Health. Diphtheria, tetanus and whole-cell pertussis (whooping cough) (DTwP) vaccine for primary immunisation. London: Department of Health, 2003.

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21

Center for Prevention Services (U.S.). Division of Immunization. Immunization of adults: A call to action. Atlanta, Ga: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, Center for Prevention Services, Division of Immunization, 1986.

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22

F, Brin Mitchell, Jankovic Joseph, and Hallett Mark, eds. Scientific and therapeutic aspects of botulinum toxic. Philadelphia: Lippincott William & Wilkins, 2002.

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23

Inc.) Resources for Child Health (John Snow. Neonatal tetanus elimination: Issues and future directions meeting proceedings REACH/MotherCare Alexandria, Virginia 9-11 January 1990. Arlington, Va: REACH, 1990.

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24

Management Sciences for Health (Firm) and Immunization and Other Child Health Project (Bangladesh), eds. Vaccination coverage survey of the Kushtia municipality, October 2001. Dhaka: [s.n.], 2001.

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25

S, Wheeler Ben, ed. Trends in diphtheria research. New York: Nova Science Publishers, 2006.

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26

Management Sciences for Health (Firm), Immunization and Other Child Health Project (Bangladesh), and Saving Newborn Lives (Save the Children (U.S.)), eds. Vaccination coverage survey of routine EPI and 2001 MNT campaign in the slums of Dhaka City corporations, September 2001. Dhaka: [s.n.], 2002.

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27

S, Anselmo Andreotti. Controversia sobre la vacuna antitetánica de Bolivia a Filipinas (1992): Primer intento de aclarar en forma popular la esterilización inmumológica. Cochabamba, Bolivia: [s.n.], 1999.

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28

Kesehatan, Indonesia Departemen, ed. Hasil survei kematian tetanus neonatorium, kematian bayi dan kematian karena komplikasi campak di daerah perkotaan Propinsi Sumatera Barat, Maret 1986. [Padang]: Kantor Wilayah Departemen Kesehatan Propinsi Sumatera Barat, 1986.

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29

Center for Prevention Services (U.S.). Division of Immunization. Parents guide to childhood immunization: Diphteria, tetanus (lockjaw), pertussis (whooping cough), polio, measles, mumps, rubella (german measles), haemophilus influenzae type b (hib). Atlanta, Ga: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, Center for Prevention Services, Division of Immunization, 1988.

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30

Center for Prevention Services (U.S.). Division of Immunization. Parents guide to childhood immunization: Diphteria, tetanus (lockjaw), pertussis (whooping cough), polio, measles, mumps, rubella (German measles), haemophilus influenzae type b (hib). Atlanta, Ga: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, Center for Prevention Services, Division of Immunization, 1991.

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31

Putera, Sharif, ed. Menunggu tetamu. Kuala Lumpur: Dewan Bahasa dan Pustaka, 2005.

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32

Rostock, Paul. Tetanus. de Gruyter GmbH, Walter, 2011.

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33

Tetanus. Oxford University Press, USA, 1994.

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34

Berger, Stephen, and Inc Gideon Informatics. Tetanus: Global Status. Gideon Informatics, Incorporated, 2019.

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35

Berger, Stephen, and Inc Gideon Informatics. Tetanus: Global Status. Gideon Informatics, Incorporated, 2021.

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36

Berger, Stephen, and Inc Gideon Informatics. Tetanus: Global Status. Gideon Informatics, Incorporated, 2022.

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37

Gideon science GIDEON science team. Tetanus: Global Status. Gideon Informatics, Incorporated, 2023.

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38

Stafstrom, Carl E. Disorders Caused by Botulinum Toxin and Tetanus Toxin. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0156.

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Anaerobic organisms of the genus Clostridia (C) can cause significant human disease. Exotoxins secreted by C botulinum and C tetani cause botulism and tetanus, respectively (summarized in Table 156.1). Botulinum neurotoxin causes neuromuscular blockade by interfering with vesicular acetylcholine release, leading to cholinergic blockade at the neuromuscular junctions of skeletal muscle, and consequently, symmetric flaccid paralysis. Tetanus toxin prevents release of inhibitory neurotransmitters at central synapses, leading to overactivity of motor neurons and muscle rigidity and spasms. This chapter reviews clinical features of botulism and tetanus and discusses their pathophysiological basis.
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39

Seventh International Conf Tetanus Hb: Seventh International Conference on Tetanus. Gangemi, 1985.

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40

Lipman, Jeffrey, and Robert J. Boots. Diagnosis, assessment, and management of tetanus, rabies, and botulism. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0245.

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Tetanus, rabies and botulism are all infections characterized by the production of a neurotoxin, and generally do not give rise to a systemic inflammatory response. Typically tetanus result from the infection of wounds by the ubiquitious soil-borne bacteria Clostridium tetanii, botulism is most commonly due to toxin produced in food contaminated with Clostridium botulinum. Rabies usually results from an animal bite infected with the rabies virus of the Lyssavirus group. Neurological involvement by all three infections is characterized by paralysis and autonomic instability with tetanus also being associated with muscular rigidity. Importantly, the autonomic dysfunction of tetanus can be severe and may necessitate prolonged treatment in an intensive care unit (ICU). Active immunization can prevent or minimize the symptoms of tetanus and rabies, while passive immunization may slow symptom progression in botulism. Intensive care support is often required to manage respiratory failure and autonomic dysfunction. Rabies is typically fatal in the absence of prior immunization.
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41

Ranke, Johannes. Tetanus: Eine Physiologische Studie. Creative Media Partners, LLC, 2018.

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42

Ranke, Johannes. Tetanus: Eine Physiologische Studie. Creative Media Partners, LLC, 2018.

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43

Dreyfus, Georges L. Die Behandlung des Tetanus. Springer London, Limited, 2013.

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44

Abnormal Forms of Tetanus. Creative Media Partners, LLC, 2023.

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45

Botulinum Neurotoxin and Tetanus Toxin. Elsevier, 1989. http://dx.doi.org/10.1016/b978-0-12-644445-2.x5001-6.

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46

Simpson, Lance. Botulinum Neurotoxin and Tetanus Toxin. Elsevier Science & Technology Books, 2012.

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47

Guilfoile, Patrick Ph D. Tetanus (Deadly Diseases and Epidemics). Chelsea House Publishers, 2008.

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48

McCabe, VC. Give the Bard a Tetanus Shot. Vegetarian Alcoholic Press, 2019.

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49

Six Fang Marks & a Tetanus Shot. Jacana Media, 2008.

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50

Treatise on Tetanus, Essay. Jacksonian Prize 1834. Creative Media Partners, LLC, 2023.

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