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Dissertations / Theses on the topic 'Testy integrity'

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Published: 28 June 2021
Last updated: 12 February 2022

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1

Hankes, Judith [Verfasser]. "Die inkrementelle Validität eines Integrity-Tests in Bezug auf Ausbildungserfolg : kann ein Integrity-Test ein Interview ersetzen? / Judith Hankes." Bonn : Universitäts- und Landesbibliothek Bonn, 2011. http://d-nb.info/1016151683/34.

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2

Corthern, Christopher. "Faking Integrity Tests: More than a Mindset?" TopSCHOLAR®, 2002. http://digitalcommons.wku.edu/theses/648.

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Personnel selection procedures often include integrity tests to aid in the attempt to hire the best possible candidates for a given job. Meta-analyses of integrity test validity coefficients have found evidence of incremental validity in the prediction of many performance criteria, but questions remain regarding the nature of the construct they actually measure. The classical interpretation of higher integrity scores being linked with higher job performance is that honest people are more productive. This study surveys another possibility: those that score highly on these measures may possess higher degrees of a problem solving ability related to intelligence that allows them to beat the test. The purpose of the following study was to determine whether a connection exists between the degree of success at faking a commercially available overt integrity test and the intelligence of the test taker. We administered an overt integrity test twice to a sample of college students with instructions to answer honestly on one administration and fake good on the other. Participants also completed measures of general and practical intelligence. Correlations between the difference of the honest and faked administrations of the integrity test and the measures of general and practical intelligence were computed in order to investigate the relationship between faking success and intelligence. Overall, a weak positive relationship between general intelligence and faking success was found, r = .17. An investigation of more specific integrity test characteristics revealed more about the nature of the overall relationship. Several limitations concerning the measure of faking success employed by this study are addressed.
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3

Du, Toit Danielle. "The development of an ethical integrity test." Thesis, Stellenbosch : Stellenbosch University, 2015. http://hdl.handle.net/10019.1/98098.

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Thesis (MCom)--Stellenbosch University, 2015
ENGLISH ABSTRACT : This study investigated the growing phenomenon of counterproductive work behaviour, and how personality and integrity affects this. It was deemed important to establish what contributes to counterproductive work behaviour. The aim of this study was to develop a new ethical integrity test and to investigate existing relationships between constructs that play a significant role in behavioural integrity. These constructs include honesty, conscientiousness, and counterproductive work behaviour. This study was therefore undertaken to develop an ethical integrity test and to determine the initial construct validity of the new test. Based on existing literature, a theoretical model depicting how the different constructs are related to one another was developed and various hypotheses were formulated. Data for the purpose of the quantitative study were collected by means of an electronic web-based questionnaire. A total of 318 completed questionnaires were returned. The final questionnaire comprised the newly developed ethical integrity test, HEXACO Personality Inventory-Revised (HEXACO-PI-R), and the Interpersonal and Organisational Deviance Scale. The postulated relationships and the conceptual model were empirically tested using various statistical methods. Reliability analysis was done on all the measurement scales and satisfactory reliability was found. The content and structure of the measured constructs were investigated by means of confirmatory factor analyses. The content and structure of the newly developed Ethical Integrity Test was also investigated by means of exploratory factor analysis. The results indicated that reasonable good fit was achieved for all the refined measurement models. Subsequently, Structural Equation Modelling (SEM) was used to determine the extent to which the conceptual model fitted the data obtained from the sample and to test the hypothesised relationships between the constructs. The results indicated positive relationships between honesty and ethical integrity; conscientiousness and ethical integrity; and conscientiousness and honesty. Furthermore, the results indicated negative relationships between ethical integrity and counterproductive work behaviour; as well as honesty and counterproductive work behaviour. The present study contributes to existing literature on counterproductive work behaviour by providing insights into the relationships between honesty, conscientiousness, ethical integrity. This study developed an Ethical Integrity Test based on recent ethics literature. Preliminary evidence of reliability and construct validity for the Ethical Integrity Test was found. The limitations and recommendations present additional insights and possibilities that could be explored through future research studies.
AFRIKAANSE OPSOMMING : Hierdie studie ondersoek die groeiende verskynsel van teenproduktiewe gedrag in die werksomgewing en hoe persoonlikheid en integriteit dit beïnvloed. Dit was dus belangrik om vas te stel wat tot teenproduktiewe werksgedrag bydra. Die doel van hierdie studie was om 'n etiese integriteitstoets te ontwikkel en bestaande verwantskappe tussen konstrukte wat 'n beduidende rol in teenproduktiewe werksgedrag speel, te ondersoek. Hierdie konstrukte sluit eerlikheid, konsensieusheid en integriteit in. Hierdie studie is dus uitgevoer om meer duidelikheid oor hierdie aspekte te verkry, sowel as om ‘n etiese integriteitstoets te ontwikkel. ‘n Teoretiese model wat voorstel hoe die verskillende konstrukte aan mekaar verwant is, is op grond van die navorsing oor die bestaande literatuur ontwikkel. Verskeie hipoteses is hiervolgens geformuleer. Data vir die doel van die kwantitatiewe studie is deur middel van ‘n elektroniese web-gebaseerde vraelys ingesamel. ‘n Totaal van 318 voltooide vraelyste is terug ontvang. Die finale vraelys is uit drie subvraelyste saamgestel, naamlik die nuut ontwikkelde etiese integriteitstoets, HEXACO Personality Inventory-Revised (HEXACO-PI-R), en die Interpersonal and Organisational Deviance Scale. Die gepostuleerde verwantskappe en die konseptuele model is empiries met behulp van verskeie statistiese metodes getoets. Betroubaarheidsanalise is op die betrokke meetinstrumente uitgevoer en voldoende betroubaarheid is gevind. Die inhoud en die struktuur van die konstrukte wat deur die instrumente gemeet is, is verder deur middel van verkennende en bevestigende faktorontledings ondersoek. Die resultate het redelike goeie passings vir al die hersiene metingsmodelle getoon. Daarna is struktuurvergelykingsmodellering (SVM), gebruik om te bepaal tot watter mate die konseptuele model die data pas, en om die verwantskappe tussen die verskillende konstrukte te toets. Die resultate het positiewe verwantskappe tussen eerlikheid en etiese integriteit; konsensieusheid en etiese integriteit; asook konsensieusheid en eerlikheid getoon. Die resultate het verder negatiewe verwantskappe tussen etiese integriteit en teenproduktiewe werksgedrag; asook eerlikheid en teenproduktiewe werksgedrag getoon. Hierdie studie dra by tot die bestaande literatuur betreffende teenproduktiewe werksgedrag, deurdat dit insig bied in die aard van die verwantskappe tussen die konstrukte. ‘n Etiese Integriteit Toets is ontwikkel gebasseer op onlangse etiek literatuur. Voorlopige bewyse van betroubaarheid en konstruk geldigheid is bewys in hierdie studie. Die beperkings en aanbevelings van die studie dui op verdere insigte en moontlikhede wat in toekomstige navorsing ondersoek kan word.
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4

Glenn, Gregory J., Nhattrieu Duong, and Jason L. Speyer. "Integrity Analysis and Fault Detection of Flight Test Data." International Foundation for Telemetering, 2010. http://hdl.handle.net/10150/605936.

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ITC/USA 2010 Conference Proceedings / The Forty-Sixth Annual International Telemetering Conference and Technical Exhibition / October 25-28, 2010 / Town and Country Resort & Convention Center, San Diego, California
Undetected sensor malfunctions during flight testing can lead to cost overruns and program delays. Determining the presence of these faults in a timely manner allows the operator to mitigate their effect. One way to detect these faults is to use a priori knowledge of sensor calibration data and system dynamics to calculate measurement uncertainties. These can then be used to determine the integrity of the sensor data and report violations of expected sensor behavior. Analytical redundancy methods and residual processing can be used in conjunction with a priori sensor information to detect faults otherwise unobserved with single-instrument data as well as to isolate and identify failure modes. These simulation and analysis methods have been implemented as MATLAB® Simulink® blocks and were used to model the flight instruments, detect anomalies in the navigation instruments, and locate the origin of the errors of a flight test data set.
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5

Palanski, Michael Edward. "Integrity and leadership a multi-level conceptual model and partial test /." Diss., Online access via UMI:, 2007.

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6

Stewart, Caitlin. "Job Applicant Faking of Overt Integrity Tests: Fact or Fantasy?" TopSCHOLAR®, 2004. http://digitalcommons.wku.edu/theses/518.

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Integrity tests are among the least utilized pre-employment selection instruments due, at least in part, to concern regarding the ease at which applicants can successfully fake their responses. The current study attempted to assess the extent to which actual job applicants fake overt integrity tests. We assigned one group of applicants to an honest condition and one group to a standard response condition. Applicants in the honest condition received a set of instructions that were modified to illustrate the importance of responding as honestly as possible when completing the questionnaire, whereas the standard response condition received a set of instructions that were not modified. We hypothesized that job applicants in the honest group would score worse on the integrity test and social desirability scales than would applicants completing the tests under the normal instructions. We failed to find a significant difference between groups on the scores on the integrity test but did find a significant difference between the groups on the social desirability scale.
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7

Asokan, Anu. "Signal Integrity - Aware Pattern Generation for Delay Testing." Thesis, Montpellier, 2015. http://www.theses.fr/2015MONTS206/document.

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La miniaturisation des circuits intégrés permet d'avoir une intégration plus élevée dans une même puce. Cela, conduit a des problèmes de qualité dans les signaux de communication et d’alimentation comme le phénomène de bruit de diaphonie entre les interconnections (Crosstalk) et de bruit dans le lignes d'alimentation (PSN, GB). Aussi problèmes de fiabilité peuvent éventuellement arriver a cause des variations dans les paramètres technologiques pendant le processus de fabrication. De ce fait, tout ces phénomènes ont un effet négatif sur le délai dans les circuits embarques (IC) et donnent lieu aux défauts sur le retard. Des échecs relie au délai dans les dispositifs semi conducteurs causes une augmentation de taux d'évasion de défaut, une perte de rendement et une diminution dans le taux de fiabilité. Techniques de Design-For-Test ont était développée a fin d'avoir une meilleur contrôlabilité et observabilité dans les nœuds internes du circuit pour détecter et localiser facilement l’emplacement des défauts. Cependant, ils ne sont pas toujours détectés par les modèles de défauts traditionnels.Cette thèse s’intéresse a l’analyse de ces phénomènes a fin de proposer de nouvelle méthodes de test du délai en considérant les phénomènes physiques pour faire face aux défauts provenant du processus de fabrication ou de problèmes physiques. Ces méthodes comprennent l'analyse de la variation du retard d'un chemin en présence du bruit de diaphonie, du bruit d'alimentation, et les variations de processus. Additionnellement, nous développons méthodes d'essai de retard sur un chemin pour identifier les motifs de test qui peuvent causer le pire des cas de retard sur un chemin cible. Les méthodes proposées peuvent être utilisées pour caractériser la vitesse de chemin et il contribue à résoudre le problème de «speed binning». En outre, ils peuvent être utilisés dans l'amélioration de l'approche classique ATPG de génération de «patterns» et elles sont indépendantes de la technologie. L'application de ces contributions peut apporter des améliorations considérables à la qualité de test IC en assurant une meilleure couverture des défauts et en aidant à augmenter le rendement de fabrication au cours de la vitesse du «binning» dans les puces IC. L’évolution en continue de la technologie en échelle nanométrique
Advancing nanometer technology scaling enables higher integration on a single chip with minimal feature size. As a consequence, the effects of signal and power integrity issues such as crosstalk noise between interconnects, power supply noise and ground bounce in the supply networks significantly increases. Also, reliability issues are eventually introduced by variations in the manufacturing process. These issues will negatively impact the timing characteristics in an integrated circuit (IC), as they give rise to delay defects. Delay-related parametric failures increase the defect escape rate, yield loss and diminish reliability rate. Hence, design-for-test techniques are employed to have a better controllability and observability on the internal nodes to easily detect and locate the faults. However, they are not always detected by the traditional fault models. In our work, we target these challenges and propose novel physical design-aware path delay test methods to deal with delay faults coming from manufacturing defects or physical design issues. They include the investigation of path delay variations in the presence of crosstalk noise, power supply noise, ground bounce and process variations. Based on this, we develop technology independent test methods for identifying the test patterns that may cause a worst-case delay on a target path. Then, we develop a dedicated test pattern generation method for path delay testing in the presence of crosstalk noise, power supply noise and ground noise. The proposed methods can be used to characterize the path speed and it helps to address the speed binning problem. Also, they can be employed in improving the classical ATPG approach of pattern generation. The application of these contributions can bring tremendous improvements to the IC test quality by ensuring better defect coverage and for an increased manufacturing yield during speed binning of IC chips
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8

Searles, Nannette Shayne. "A Comparative Study of Integrity Tests: The Effect of Situational and Individual Variables on Response Distortion." PDXScholar, 1995. https://pdxscholar.library.pdx.edu/open_access_etds/5061.

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The paper-and-pencil integrity test, which is used in industry as an employee selection device, has been largely developed outside the mainstream of psychological testing. The result has been that some testing programs have inadequately standardized testing conditions and/or other safeguards to ensure valid test results. Studies have shown that response distortion, or faking, is a problem with all types of tests, integrity tests being no exception. A correlation between the construct underlying integrity testing, such as the personality trait of conscientiousness, has yet to be investigated. The primary purpose of the present study was to determine how response distortion on integrity tests is affected by the instructions given by test administrators. Also, the connection between integrity tests and conscientiousness is examined. Finally, comparisons were made between currently published integrity tests/scales. Two hundred and forty-nine college students participated in this study by completing the following three integrity tests and two personality test scales: The London House Personnel Selection Inventory (London House Press, Inc., 1980); The Tescor Survey (Bullard, 1992); The Reid Report (Reid, 1967); The Value Orthodoxy Scale from The Jackson Personality Inventory (Jackson, 1976), and the Work Orientation Scale from the California Personality Inventory (Gough, 1985). The three integrity tests offer a variety of validation studies in support of their scales. Also, all three test publishers participated in a pre-publication review of the 1991 APA Task Force Report on integrity testing (Goldberg, Grenier, Guion, Sechrest, & Wing). Results show that responses were affected by instructions given by the administrator. For example, the analysis shows that in a job application situation, an applicant who believes a prospective employer is using an integrity test to identify undesirable applicants will tend to distort his/her responses on a theft scale to appear more favorable. Also for the theft scales, instructions to deliberately give false responses in a socially desirable way did not differ from a standard job applicant instruction set. Instructions emphasizing the ability of the tests to identify high integrity employees also did not differ from the standard instruction set's results. Results also show that conscientiousness is correlated with integrity test scales. Finally, the integrity tests and personality scales studied here are significantly correlated. Implications of these findings are discussed.
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9

Laginess, Andrew J. "Mapping Integrity in the Domain of Trait Personality." FIU Digital Commons, 2016. http://digitalcommons.fiu.edu/etd/3365.

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This thesis was conducted to empirically examine and compare the different conceptualizations of the integrity test construct identified in previous research. The conceptualizations assert that integrity tests measure a major trait (i.e., Conscientiousness or Honesty-Humility), a combination of major traits, or a combination of minor traits (personality facets). The general fit and predictive validity (of counterproductive work behavior, or CWB) of each conceptualization was tested. Psychology undergraduates (N = 436) participated via online surveys containing two personality scales, two integrity tests, and a CWB scale. The results most support the conceptualizations of integrity as either solely the broad trait Conscientiousness or a combination of Conscientiousness, Agreeableness, and Neuroticism. Statistical issues were encountered with the models of several conceptualizations due to the number of predictors used and high multicollinearity between them. A closer examination revealed that integrity tests mostly encompass behaviors typically associated with the traits Conscientiousness and Agreeableness.
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10

Burton, Simon. "Automated generation of high-integrity test suites from graphical specifications." Thesis, University of York, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270360.

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11

Zargarzadeh, Payam. "Structural integrity of Carbon Dioxide transportation infrastructures." Thesis, Cranfield University, 2013. http://dspace.lib.cranfield.ac.uk/handle/1826/8059.

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Carbon Capture and Storage (CCS) is recognised as having a significant role to play in tackling climate change and reducing carbon dioxide (CO2) emissions. In CCS schemes, CO2 is captured from anthropogenic sources, and transported to suitable sites either for EOR (Enhanced Oil Recovery) or storage. The transport of such huge amount of CO2 causes new challenges. The main concern is in the difference between natural gas and CO2 transportation pipelines. CO2 phase behaviour during decompression, existence of different impurities and very high operating pressure are some of the new challenges for pipeline designer and operators. This PhD study has taken a systematic approach to understand the mechanics involved in the fracture of pipes containing high pressure flue-gas CO2. The work involved the development of a novel weight function stress intensity factor solution that can be used with complex stress fields induced by residual and/or thermal stresses in addition to applied pressure. In addition, the thesis reports a substantial experimented test programme which involved low temperature fracture toughness tests linked to a detailed finite element based stress analysis. Overall, the thesis presents an integrated engineering criticality means to assess the suitability or otherwise of a pipeline system to transport high pressure flue-gas CO2.
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Blumen, Sheyla, Hugo Bayona, Simon Givoli, Gabriela Pecker, and Saul Fine. "Validation study of a multi-method integrity test in a Peruvian sample." Pontificia Universidad Católica del Perú, 2016. http://repositorio.pucp.edu.pe/index/handle/123456789/100945.

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The present study summarizes the validity of a multi-method integrity test developed to measure integrity and counterproductive work behaviors (CWB) in personnel selection of a Peruvian sample. This instrument has been thoroughly studied in other cultural contexts, establishing its validity in predicting counter-productive behaviors. In order to study external validity, two criteria were used: (a) The Counterproductive Work Behavior Checklist (CWB-C) and (b) a supervisor evaluation questionnaire. The criterion validity of the Peruvian Spanish version was studied with a sample of 194 employed students, 86 male (44.3%) and 108 (55.7%) female. Participants were recruited from a large private Peruvian university. The instrument’s overall score correlated with self-reported CWB (r= -.62, p <.01). Regarding the other criterion, only the Ethical Dilemmas sub-scale showed a significant correlation with supervisor-rated CWB (r=.18, p< .05). Female participants reported higher scores than male participants on the Attitudes (U (193) = 3842.5, p<.05), Ethical Dilemmas (U (193) = 3619.5, p<.05), and Past Behaviors (U (193) = 3463.5, p<.01) dimensions of the integrity test (r=.15-.22), as well as on the overall score (U (193) = 3395.5, p<.01). Results support the validity of the multi-method integrity measure to predict counterproductive work behaviors, without adverse gender impact.
El presente estudio evaluó la validez de una prueba de integridad multimétodo desarrollada para medir la integridad y las conductas contraproducentes en el trabajo (CWB) en la selec­ ción de personal en una muestra peruana. La prueba ha sido estudiada en otros contextos culturales, habiéndose probado su validez en la predicción de conductas contraproducentes (Fine & Pecker, 2015). Para la validez externa, se usaron dos criterios: (a) La lista de cotejo de conductas contraproducentes en el trabajo/The Counterproductive Work Behavior Chec­ klist (CWB-C), y (b) un cuestionario de evaluación dirigido a los supervisores. Para la validez de criterio, según el español que se habla en el Perú, se consideró una muestra de 194 estudiantes que trabajan, 86 hombres (44.3%) y 108 (55.7%) mujeres, quienes fueron reclutados de una universidad privada peruana. El puntaje total de la prueba correlacionó significativamente con el autorreporte de CWB (r=-.62, p<.01). En el segundo criterio solo la dimensión de Dilemas éticos mostró una correlación significativa con la evaluación del supervisor (r=.18, p<.05). Las participantes mujeres reportaron puntajes más altos que los varones para las dimensiones de Actitudes (U (193) = 3842.5, p<.05), Dilemas Éticos (U (193) = 3619.5, p<.05) y Comportamiento Pasado (U (193)= 3463.5, p<.01) de la prueba de integridad (r=.15-.22), así como en el puntaje final (U (193) = 3395.5, p<.01). Los resul­ tados del presente estudio apoyan la validez de la prueba de integridad multi-método para predecir las conductas contraproducentes en el trabajo, sin un impacto adverso de género.
Este estudo avaliou a validade de um teste multi-método desenvolvido para medir a inte­ gridade e comportamentos contraproducentes no trabalho (CWB) na seleção de pessoal no Peru. Este teste tem sido estudado extensivamente em outros contextos culturais e foi encon­ trado válida e eficaz na predição de comportamentos contraproducentes (Fine & Pecker, 2015). Para validade externa, foram utilizados dois critérios. (a) The Counterproductive Behavior Checklist (CWB-C), e (b) um questionário de avaliação dirigido a supervisores. Para estudar a validade de critério da versão em espanhol peruana do teste, uma amostra de 194 estudantes que trabalham foi usado, 86 homens (44,3%) e 108 (55,7%) mulheres, recrutados a partir de uma grande universidade privada no Peru. A pontuação total do teste correlação significativa com CWB auto-reportado (r = -. 62, p <0,01). Sobre o segundo critério, apenas a dimensão de dilemas éticos do teste mostrou uma correlação significa­ tiva com a avaliação do supervisor (r = 0,18, p <0,05). Mulheres participantes relataram uma maior pontuação que os homens para as dimensões de Atitudes (U (193) = 3842.5, p<.05), Dilemas Éticos (U (193) = 3619.5, p<.05), e Comportamento passado (U (193)= 3463.5, p<.01) do teste de integridade (r = 0,15-0,22). Os resultados deste estudo reforçam a validade de teste multi-método do integridade de prever comportamentos de trabalho contraproducentes, sem um impacto adverso do género.
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Impelman, Kevin. "Predicting Counter-Productive Workplace Behavior: Item Level Analysis of an Integrity Test." Thesis, University of North Texas, 2006. https://digital.library.unt.edu/ark:/67531/metadc5602/.

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Counter-productive workplace behavior (CWB) is defined as any intentional behavior on the part of an organization member viewed by the organization as contrary to its legitimate interests. A growing body of literature reveals that individual variables and pre-employment integrity tests can play a strong role in the prediction of CWB. The empirical literature has failed to clarify which type of individual level antecedents, or types of integrity test items, are more predictive of CWB. The current study evaluated data collected from restaurant employees (N=464) that measured items relating to personality tendencies, attitudes toward acceptance of counter-productive behaviors, work and high school background, and admissions of counter-productive behavior. A confirmatory factor analysis revealed a mediocre fit to a typology of CWB (interpersonal CWB vs. organizational CWB). Correlation analysis revealed that only specific attitudinal items and empirically keyed biodata items were significantly related to CWB. Hierarchical regression analysis found that attitudinal items paralleling admissions of CWB contributed variance beyond that of other personality and work and high school background antecedents.
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Mignogna, Alessandro. "Progettazione di un gruppo test di integrità per sacche farmaceutiche." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2016.

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Nel quarto capitolo introduco il problema e spiego il funzionamento generale della macchina senza essere troppo dettagliato per mantenere i segreti industriali che siamo tenuti a rispettare. Le proposte di soluzioni sono state sviluppate sia da me, ragionando sul gruppo singolo ma anche sul gruppo complessivo in generale, altre invece sono state proposte dal mio correlatore, l’ingegner Fabrizio Rimondi, e anche il confronto con altri colleghi dell’ufficio tecnico è stato fondamentale per la realizzazione e il funzionamento del gruppo. Nel capitolo successivo ho spiegato in dettaglio le mie idee di soluzioni mettendo i relativi disegni di ogni componente di volta in volta dopo ogni modifica significativa. Ad ogni proposta ho cercato sempre di mettere le mie opinioni in merito cercando di valutare al meglio ogni tipo di approccio. Durante lo studio dei vari casi mi sono interfacciato continuamente con i fornitori per sapere se alcune delle nostre idee fossero realizzabili e quindi capire se continuare con una certa decisione o cambiare metodo di risoluzione. Dopo aver ideato 4 tipi di soluzioni abbiamo avuto un confronto con l’azienda cliente sentendo anche la loro opinione e arrivando alla decisione finale, portando delle modifiche a una delle soluzioni che ci è sembrata la più adatta al caso. Successivamente per capire se quel tipo di soluzione fosse possibile da implementare ho cercato vari fornitori per sentire la loro opinione e sapere se alcuni componenti fossero realizzabili portando le ultime modifiche alle singole parti. Successivamente nel settimo capitolo ho iniziato uno studio sul gruppo pompa da scegliere per collegarlo al gruppo oggetto di studio. Inizialmente ho fatto un’introduzione generale sulle pompe a vuoto e compressori volumetrici, dopodiché ho cercato, tra i vari cataloghi disponibili su internet, una pompa a vuoto idonea per i parametri richiesti dall’azienda cliente.
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15

Sýkora, Milan. "Analýza mechanických vlastností bimetalových materiálů s cladovanou vrstvou Inconelu." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2020. http://www.nusl.cz/ntk/nusl-417099.

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This diploma thesis deals with the analysis of mechanical properties of bimetallic materials with clad layer of Inconel. In the theoretical part of the work there is an analysis of the investigated bimetallic material. The following is a description of mechanical tests and methods for evaluating the integrity of the surface, which were used to determine the properties of bimetallic material. The experimental part focuses on individual tests of mechanical properties of the material. For each test, the procedure for the production of test specimens, a description of the test equipment, the performance of the tests, the evaluation of the data obtained and finally, the evaluation of the results obtained are given.
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Taboada, Efren De Jesus Rangel. "Improved Signal Integrity in IEEE 1149.1 Boundary Scan Designs." Diss., CLICK HERE for online access, 2004. http://contentdm.lib.byu.edu/ETD/image/etd587.pdf.

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17

Flynn, Atkinson Kerry. "Integrity in the Administration of Curriculum-Based Measurement: A Seminal and Exploratory Study." Miami University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=miami1340828828.

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18

Coyne, Iain J. "Factors impacting on the design, development and use of an effective pre-employment integrity test." Thesis, University of Hull, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.395520.

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19

Nobre, Michelle. "The OPQ 32i (Occupational Personality Questionnaire 32 Version i) as a predictor of employee theft in a financial institution." Thesis, Link to the online version, 2005. http://hdl.handle.net/10019/1143.

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20

Biondi, Michele. "Test e Progettazione di Circuiti Integrati ad Alta Risoluzione per Applicazioni Biomediche." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2013. http://amslaurea.unibo.it/5380/.

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Neyroud, Peter William. "Learning to field test in policing : using an analysis of completed randomised controlled trials involving the police to develop a grounded theory on the factors contributing to high levels of treatment integrity in Police Field Experiments." Thesis, University of Cambridge, 2017. https://www.repository.cam.ac.uk/handle/1810/268177.

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Evidence-based policing (EBP) has emerged as a key strand of police innovation since Sherman’s (1998) Police Foundation lecture. However, for others EBP raises as many questions as answers. One of the most contentious areas is the role advocated for randomised controlled trials in testing practice and developing knowledge to support EBP. RCTs are controversial with some scholars who argue that policing is not comparable to medicine and that RCTs are unable to reflect the complexity of the police role and context. Even those who advocate the use of RCTs recognise that there are significant challenges in achieving the high dosage and high fidelity that a successful experiment requires. This dissertation responds to these challenges by analysing the completed randomised controlled trials in policing and using a case study, Operation Turning Point, to identify the factors that may contribute to the conduct and management of police field trials with high levels of treatment integrity. In the introduction, Chapter 1, the approach is set out, framed around grounded theory, to be developed in four, linked, chapters. Chapter 2 is focused on understanding treatment integrity in RCTs involving the police: A search for police RCTs is produced 122 Police RCTs completed and reported by 2016. The levels of treatment integrity are analysed. 78 of the 122 RCTs exceeded a 60% threshold, with 49 being above 90%. In Chapter 3, a “novice theory” is developed and tested as an explanation for levels of treatment integrity in police randomised controlled trials: Analysis of the 122 RCTs suggests that “novice theory” can provide an explanation for the general patterns of treatment integrity. Further detailed analysis suggested that there are, however, other factors which may be important in determining the treatment integrity. These are developed in Chapter 4, which centres on a case study of Operation Turning Point. Using published case studies and an analysis of juvenile justice RCTs, a potential framework of operational factors is developed that appear to be important in effective conduct and management. The Turning Point case study is used to develop and expand on those operational factors. Finally, taking the two together, the analysis concluded that, beyond the operational factors, there were some more strategic, “protective factors” that were also critical. These are developed in Chapter 5, by using the coding and analysis of interviews with a sample of key staff involved in Turning Point Our analysis suggests that novice theory needs to be understood in the context of both the operational and protective factors that we have identified. Taken together these findings indicate the potential advantages of building institutional frameworks in which the development of practitioners and researchers and the conduct and management of experimental research could be brought closer together. We conclude with ten recommendations designed to improve the treatment integrity of police RCTs.
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Dupray, Sebastien. "Integrity of rock blocks for armouring of hydraulic works : towards full-scale test to predict mass distribution changes." Thesis, Imperial College London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.420579.

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23

Spartà, Antonino Maria <1977&gt. "Development of screening assays to test novel integrin antagonists in allergic inflammation." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2009. http://amsdottorato.unibo.it/1613/.

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Aim of the research: to develop a prototype of homogeneous high-throughput screening (HTS) for identification of novel integrin antagonists for the treatment of ocular allergy and to better understand the mechanisms of action of integrin-mediated levocabastine antiallergic action. Results: This thesis provides evidence that adopting scintillation proximity assay (SPA) levocabastine (IC50=406 mM), but not the first-generation antihistamine chlorpheniramine, displaces [125I]fibronectin (FN) binding to human a4b1 integrin. This result is supported by flow cytometry analysis, where levocabastine antagonizes the binding of a primary antibody to integrin a4 expressed in Jurkat E6.1 cells. Levocabastine, but not chlorpheniramine, binds to a4b1 integrin and prevents eosinophil adhesion to VCAM-1, FN or human umbilical vein endothelial cells (HUVEC) cultured in vitro. Similarly, levocabastine affects aLb2/ICAM-1-mediated adhesion of Jurkat E6.1 cells. Analyzing the supernatant of TNF-a-treated (24h) eosinophilic cells (EoL-1), we report that levocabastine reduces the TNF-a-induced release of the cytokines IL-12p40, IL-8 and VEGF. Finally, in a model of allergic conjunctivitis, levocastine eye drops (0.05%) reduced the clinical aspects of the early and late phase reactions and the conjunctival expression of a4b1 integrin by reducing infiltrated eosinophils. Conclusions: SPA is a highly efficient, amenable to automation and robust binding assay to screen novel integrin antagonists in a HTS setting. We propose that blockade of integrinmediated cell adhesion might be a target of the anti-allergic action of levocabastine and may play a role in preventing eosinophil adhesion and infiltration in allergic conjunctivitis.
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Lin, Yue. "Relationship of the PDI Employment Inventory Scales to Criminal Behaviors." Thesis, University of North Texas, 2005. https://digital.library.unt.edu/ark:/67531/metadc4860/.

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This study investigated the relationship of the Personnel Decisions International Employment Inventory scales to criminal behavior by using 796 offenders with criminal records in the Texas Department of Corrections and a random sample of 893 non-offender job applicants. The hypothesis that offenders would score lower in integrity scores than non-offenders only gained mixed support, but consistent evidence showed that there were no mean differences between property offenders and other offenders. The implications of the results for future study were discussed.
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Heim, Eugene Henry DeWendt. "Development of Methods for Improved Data Integrity and Efficient Testing of Wind Tunnel Models for Dynamic Test Conditions in Unsteady and Nonlinear Flight Regimes." Thesis, Virginia Tech, 2003. http://hdl.handle.net/10919/31050.

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Todayâ s high performance aircraft are operating in expanded flight envelopes, often maneuvering at high angular rates at high angles-of-attack, even above maximum lift. Current aerodynamic models are inadequate in predicting flight characteristics in the expanded envelope, such as rapid aircraft departures and other unusual motions. Unsteady flows of aircraft are of real concern. The ability to accurately measure aerodynamic loads directly impacts the ability to accurately model and predict flight. Current wind tunnel testing techniques do not adequately address the data fidelity of a test point under the influence of fluctuating loads and moments. Additionally, forced oscillation test techniques, one of the primary tools used to develop dynamic models, do not currently provide estimates of the uncertainty of the results during an oscillation cycle. Further, in testing models across a range of flight conditions, there are frequently parts of the envelope which are well behaved and require few data points to arrive at a sound answer, and other parts of the envelope where the responses are much more active and require a large sample of data to arrive at an answer with statistical significance. Currently, test methods do not factor changes of flow physics into data acquisition schemes, so in many cases data are obtained over more iterations than required, or insufficient data may be obtained to determine a valid estimate. Methods of providing a measure of data integrity for static and forced oscillation test techniques are presented with examples. A method for optimizing required forced oscillation cycles based on decay of uncertainty gradients and balance tolerances is also presented.
Master of Science
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Van, der Westhuizen Christine. "The clinical utility of the Vivosonic Integrity Auditory Brainstem response system in children with cerebral palsy." Diss., University of Pretoria, 2010. http://hdl.handle.net/2263/28152.

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Determining auditory functioning in difficult-to-test populations such as cerebral palsy (CP) remains a challenge in paediatric audiology. The auditory brainstem response (ABR) is favoured as the procedure to assess auditory functioning in difficult-to-test populations such as CP. The CP population, however, offers unique challenges for the ABR procedure due to the presence of involuntary muscular movements that may compromise the signal-to-noise ratio (SNR) of the ABR. Conventional ABR technology attempts to improve the SNR by the modification of acquisition parameters e.g. adjusting the low cut filter or implementing stricter artifact rejection criteria. However, such modifications may compromise the waveform morphology of the ABR. Furthermore, sedation or general anesthesia can also be used to improve the SNR by reducing excessive muscular movements. The CP population, however, displays a high risk for developing upper airway obstruction when being sedated or anesthetized. Thus, the feasibility and reliability of the conventional ABR may be compromised when being employed in the CP population. In recent years a novel ABR system, the Vivosonic Integrity (VS) ABR has become clinically available. The device incorporates features such as pre-amplification of the ABR signal, Kalman filtering and wireless recording. These features promise to address the limitations of conventional ABR technology to obtain a reliable recording in the midst of excessive myogenic artifact. The aim of this study was therefore to evaluate the clinical utility of the VS system when assessing a sample of children with CP without the use of sedation. The clinical utility of the VS ABR system was determined by comparing its success rates, the threshold correspondence to behavioural pure tone (PT) thresholds and recording time to a conventional ABR system when using click and 0.5 kHz TB stimuli. A cross-sectional within-subject comparison research design was selected in order to compare thresholds obtained with different procedures. The experimental part of this study was represented by the within-subject control condition where the VS ABR system and the conventional ABR system were simultaneously conducted in each subject. This unique setup was important in the research as equivalent test conditions in terms of EEG and environmental conditions had to be ensured for both ABR systems. 15 CP subjects between the ages of 12 and 18 years were included in the project. A diagnostic audiological test battery including immittance, distortion product otoacoustic emissions and behavioural audiometry was conducted on each subject prior the administration of the ABR procedures. The variability of the audiological test battery results – between the subjects and when compared to previous research – emphasized the heterogeneity of the CP population. Furthermore, more than half of the research sample (53%; n=15) responded inconsistently to behavioural pure tone (PT) stimuli. It was suggested that the severity of physical impairments as well as additional impairments such as mental retardation might have influenced the consistency of the subjects’ responses during behavioural PT audiometry. The ABR results indicated that there were no significant differences with regards to threshold correspondence and recording time between the two ABR systems when using click and 0.5 kHz TB stimuli (p>0.05). With regards to the success rates, the VS system was successful in more cases than the conventional ABR system using click and 0.5 kHz TB stimuli. Although results also showed no statistically significant value for click p=.1121) and 0.5 kHz TB stimuli p=.1648), there was a tendency towards the 95% confidence level in both cases suggesting that the VS ABR system may produce a statistically significant success rate for click as well as for 0.5 kHz TB stimuli, provided a larger sample is tested. The research indicated that, since the VS ABR system was more successful across a wider range of subjects during click-evoked and 0.5 kHz TB recordings, it may increase the clinical usefulness of the ABR especially in terms of hearing screening in the CP population. The research suggested that excessive muscular movements during the recordings influenced not only the VS ABR’s, but also the conventional ABR’s threshold correspondences to PT thresholds as well as the recording time of the measurements. Therefore it may still be necessary to use a light sedative in some CP patients to reduce excessive myogenic interference despite the possible advantages of the VS ABR system.
Dissertation (MCommunication Pathology)--University of Pretoria, 2011.
Speech-Language Pathology and Audiology
unrestricted
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du, Toit Marelise. "The influence of leader integrity on ethical leadership, interactional justice, leader trust and counterproductive work behaviour." Thesis, Stellenbosch : Stellenbosch University, 2015. http://hdl.handle.net/10019.1/97846.

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Thesis (MCom)--Stellenbosch University, 2015
ENGLISH ABSTRACT :This study arose due to the costly and harmful effect that negative behaviours have on organisations and society alike. This study is therefore undertaken to understand the determinants of these negative behaviours as well as to identify constructs that can defer these types of behaviour. The aim of the study was to study the constructs that is expected to significantly affect the occurrence of counterproductive workplace behaviours (CWB) in South African organisations. Therefore the purpose was to investigate the relationship between leader integrity, ethical leadership, interactional justice, leader trust and CWB. A theoretical model was subsequently developed to explain the structural relationships between the latent variables and counterproductive behaviours. Propositions were formulated regarding the postulated relationships found between these variables in the literature study. These hypotheses were tested to determine the validity of these propositions to subsequently test the proposed structural model. The sample encompassed employees from four organisations in the Western Cape. The respondents completed the Leader Trust Scale (LTS), the Justice Scale, Leadership of Ethics Scale (LES), Ethical Integrity Test (EIT) and the Deviance Scale. The proposed hypotheses and structural model were empirically tested by means of Partial Least Squares Analysis (PLS). These analyses included reliability analysis to determine the reliability of all the measurement scales. Satisfactorily reliability were found for all measurement scales. The structural model and the hypothesised relationships were analysed by means of the PLS path coefficients, R Square values and Pearson product-moment correlation coefficient. The results indicated that support could be found for the relationship between leader integrity and ethical leadership, leader integrity and interactional justice, leader integrity and leader trust, ethical leadership and interactional justice, and leader trust and interactional justice. Only partial support was found for the relationship between ethical leadership and leader trust, leader trust and CWB, interactional justice and CWB, ethical leadership and CWB and leader integrity and CWB. Subsequently conclusions were made from the results as well as recommendations made for future research.
AFRIKAANSE OPSOMMING : Hierdie studie het ontstaan as gevolg van die duur en skadelike effek wat negatiewe gedrag op beide organisasies en die samelewing het. Die studie is dus uitgevoer om die oorsake van hierdie negatiewe gedrag te begryp sowel as om konstrukte te identifiseer om hierdie tipes gedrag uit te skakel. Die doel van die studie was om konstrukte te ondersoek wat waarskynlik ‘n substansiële invloed op die verskynsel van teenproduktiewe gedrag in organisasies in Suid-Afrika kan hê. Die doel was dus om die verband tussen leier-integriteit, etiese leierskap, interaksionele geregtigheid, leier-vertroue en teenproduktiewe gedrag te ondersoek. ‘n Teoretiese model is ontwikkel om die strukturele verband tussen die latente veranderlikes en teenproduktiewe gedrag te verduidelik. Hipoteses is geformuleer rakende die gepostuleerde verwantskappe tussen hierdie veranderlikes soos in die literatuurstudie geïdentifiseer. Hierdie hipoteses is getoets om die geldigheid van hierdie proposisies te bepaal om uiteindelik die voorgestelde strukturele model te toets. Die steekproef is saamgestel uit werknemers van vier organisasies in die Wes-Kaap. Die proefpersone het die Leader Trust Scale (LTS), die Justice Scale, die Leadership of Ethics Scale (LES), die Ethical Integrity Test (EIT) en die Deviance Scale voltooi. Die voorgestelde hipoteses en strukturele model is empiries getoets deur middel van Partial Least Squares (PLS) ontleding. Hierdie analises sluit in ‘n betroubaarheidsanalise om die betroubaarheid van die metingskale te bepaal. Bevredigende betroubaarheid is vir al die metingskale gevind. Die strukturele model en die gepostuleerde hipoteses is ontleed deur middel van PLS path coefficients, R Square values en Pearson product-moment correlation coefficient. Die resultate het aangedui dat ondersteuning gevind is vir die verband tussen leier-integriteit en etiese leierskap, leier-integriteit en interaksionele geregtigheid, leier-integriteit en leier-vertroue, etiese leierskap en interaksionele geregtigheid, en leier-vertroue en interaksionele geregtigheid. Slegs gedeeltelike ondersteuning is gevind vir die verband tussen etiese leierskap en leier-vertroue, leier-vertroue en teenproduktiewe gedrag, interaksionele geregtigheid en teenproduktiewe gedrag, etiese leierskap en teenproduktiewe gedrag, en leier-integriteit en teenproduktiewe gedrag. Daarna is afleidings gemaak op grond van die resultate, sowel as aanbevelings gemaak vir toekomstige navorsing.
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Capron, Adélie. "Towards the predictive FE analysis of a metal/composite booster casing’s thermomechanical integrity." Doctoral thesis, Universite Libre de Bruxelles, 2020. https://dipot.ulb.ac.be/dspace/bitstream/2013/314767/5/contratAC.pdf.

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In response to serious environmental and economic concerns, the design and production of aircrafts have been changing profoundly over the past decades with the nose-to-tail switch from metallic materials to lightweight composite materials such as carbon fibre reinforced plastic (CFRP). In this context, the present doctoral research work aimed to contribute to the development of a CFRP booster casing, a real innovation in the field initiated and conducted by Safran Aero Boosters. More specifically, this thesis addresses the matter of joining metal/CFRP hybrid structures, which are prone to possibly detrimental residual stresses.The issue is treated with an approach combining experimental characterisation and finite element (FE) simulations. The multi-layered system’s state of damage was systematically examined on hundreds of micrographs, and the outcome of this study is presented under the form of a statistical analysis. Further, the defects’ 3D morphology is investigated by incremental polishing. A number of thermal and mechanical properties are measured by diverse physical tests on part of the constituent materials, i.e. the aerospace grade RTM6 epoxy resin, the structural Redux 322 epoxy film adhesive, and AISI 316L stainless steel. They are used as input data in a FE model of the multilayer that is developed and progressively refined to obtain detailed residual stress fields after thermal loading. These results are compared to experimental data acquired by X-ray diffraction stress analysis and with the curvature-based Stoney formula. Cohesive elements are placed at specific locations within the FE model to allow simulating progressive damage. Peel tests, mode I, mode II and mixed mode I/II fracture tests are thus performed in view of measuring the joint toughness. The results of these tests are discussed and the presence of residual stress in the fracture specimens is highlighted. Key information for the calibration of the cohesive law is finally identified via inverse FE analysis of the mode I test, this being a significant step in the process of building a damage predictive FE model of the multi-layered system.
Doctorat en Sciences de l'ingénieur et technologie
info:eu-repo/semantics/nonPublished
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Forni, Federico. "Controllo ottico automatizzato di circuiti fotonici integrati: Progettazione, realizzazione e valutazione." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2014. http://amslaurea.unibo.it/6473/.

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In this report a new automated optical test for next generation of photonic integrated circuits (PICs) is provided by the test-bed design and assessment. After a briefly analysis of critical problems of actual optical tests, the main test features are defined: automation and flexibility, relaxed alignment procedure, speed up of entire test and data reliability. After studying varied solutions, the test-bed components are defined to be lens array, photo-detector array, and software controller. Each device is studied and calibrated, the spatial resolution, and reliability against interference at the photo-detector array are studied. The software is programmed in order to manage both PIC input, and photo-detector array output as well as data analysis. The test is validated by analysing state-of-art 16 ports PIC: the waveguide location, current versus power, and time-spatial power distribution are measured as well as the optical continuity of an entire path of PIC. Complexity, alignment tolerance, time of measurement are also discussed.
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30

Young, Bob Neill. "Experimental neuropsychological tests of feature ambiguity, attention and structural learning : associations with white matter microstructural integrity in elderly with amnesic and vascular mild cognitive impairment." Thesis, University of Canterbury. Psychology, 2014. http://hdl.handle.net/10092/9367.

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Mild cognitive impairment (MCI) is a transition phase between normal aging and Alzheimer’s disease. Individuals with MCI show impairment in cognition as well as corresponding damage to areas of their brain. Performance on tasks such as discriminating objects with ambiguous features has been associated with damage to the perirhinal cortex, while scenes with structural (spatial) elements have been associated with damage to the hippocampus. In addition, attention is regarded as one of the first non-memory domains to decline in MCI. A relatively new MRI technique called diffusion tensor imaging (DTI) is sensitive to white matter microstructural integrity and has been associated with changes due to cognitive decline. 18 MCI (14 amnesic, 4 vascular) and 12 healthy matched controls were assessed in feature ambiguity, attention and structural learning to assess associated deficits in MCI. Associations with white matter microstructural integrity were then investigated. The MCI groups were discovered to perform worse than controls on the test of structural learning. In addition, altered attention networks were found in MCI and were associated with white matter microstructural integrity. No significant differences were found for feature ambiguity. These findings suggest there may be specific damage to the hippocampus while the perirhinal cortex may be preserved in MCI. Furthermore, dysfunction in attention was found to be associated with white matter microstructural integrity. These experimental tests may be useful in assessing dysfunction in MCI and identifying degeneration in white matter microstructural integrity. Further studies with larger sample sizes are needed to validate these findings.
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Pauly, Nicole M. "Thermal Conductivity of Soils from the Analysis of Boring Logs." Scholar Commons, 2010. http://scholarcommons.usf.edu/etd/3614.

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Recent interest in "greener" geothermal heating and cooling systems as well as developments in the quality assurance of cast-in-place concrete foundations has heightened the need for properly assessing thermal properties of soils. Therein, the ability of a soil to diffuse or absorb heat is dependent on the surrounding conditions (e.g. mineralogy, saturation, density, and insitu temperature). Prior to this work, the primary thermal properties (conductivity and heat capacity) had no correlation to commonly used soil exploration methods and therefore formed the focus of this thesis. Algorithms were developed in a spreadsheet platform that correlated input boring log information to thermal properties using known relationships between density, saturation, and thermal properties as well as more commonly used strength parameters from boring logs. Limited lab tests were conducted to become better acquainted with ASTM standards with the goal of proposing equipment for future development. Finally, sample thermal integrity profiles from cast-in-place foundations were used to demonstrate the usefulness of the developed algorithms. These examples highlighted both the strengths and weaknesses of present boring log data quality leaving room for and/or necessitating engineering judgment.
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Stokes, Michael Jeffrey. "Advancements in rapid load test data regression." [Tampa, Fla] : University of South Florida, 2006. http://purl.fcla.edu/usf/dc/et/SFE0001929.

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Pires, Adriana Helena Catojo. "Avaliação da integridade de córregos a partir das características da paisagem: teste do protocolo WHEBIP para uma região tropical." Universidade Federal de São Carlos, 2013. https://repositorio.ufscar.br/handle/ufscar/2096.

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Universidade Federal de Sao Carlos
Lotic systems are highly influenced by the landscape through which they flow, and changes in the landscape are the main threat to their ecological integrity. Evaluating the ecological "health" of lotic systems is essential and of great importance to the management of water resources worldwide. In this study, we evaluated the integrity of streams in southeastern Brazil using the protocol WHEBIP (Watershed Habitat Evaluation and Biotic Integrity Protocol), which combines information about the coverage of riparian vegetation, geomorphology, land cover and human activities to assess the physical characteristics of the sub-basin and to evaluate the integrity of streams. We compared this protocol with the protocol RCE (Riparian, Channel and Environmental), already widely used in tropical regions, to directly assess stream physical condition. As a measure of the functional integrity of streams, we estimated leaf breakdown rates, an important process in lotic systems. Furthermore, we sorted and identified the macroinvertebrates that colonized leaves in the 2nd and 28th days of the decomposition experiment and calculated environmental quality metrics related to these communities to test their relationship with WHEBIP. The protocols WHEBIP and RCE were significantly correlated to each other, with greater differentiation among streams especially when RCE was high. Possibly, the WHEBIP, by incorporating spatial variables on a large scale in the landscape, best differentiates these streams. None of the protocols tested were correlated with leaf breakdown rates. However, when calculating variation of decay rates (standard error), we observed a positive relationship with the protocol WHEBIP. Thus, we grouped the metrics of the protocol WHEBIP in a Principal Component Analysis (PCA), noting the trend to a significant correlation between changes in leaf breakdown rates and the first axis of the PCA, which indicates that the increase of forest cover in the microbasin could reduce variation in leaf breakdown rates in streams. The WHEBIP and RCE showed no correlation with the environmental quality metrics related to macroinvertebrate communities. But we tested the hypothesis that higher values of WHEBIP decreases the variation in leaf breakdown rates due to higher stability of macoinvertebrate communities, we found a significant correlation to withdraw one of the streams of the analysis. This stream differed greatly from the rest, because even getting down in value in WHEBIP, showed a differentiation between communities, due to the dominance of certain taxa in the days analyzed. This is the first study in the tropics that relates the variation in leaf breakdown rates in streams and forest cover of the microbasin within they are inserted. Our results suggest that WHEBIP protocol can be used to assess the integrity of streams in tropical regions. This protocol showed significant relationships with the variation in leaf breakdown rates, which may prove to be an interesting metric for use in monitoring, and the stability of the macroinvertebrate community, which is greater in less impacted streams, as suggested by other studies.
Os sistemas lóticos são extremamente influenciados pela paisagem através da qual fluem, e as transformações na paisagem são a principal ameaça à sua integridade ecológica. Avaliar a saúde ecológica dos sistemas lóticos é fundamental e de grande importância para o manejo dos recursos hídricos em todo o mundo. Neste estudo, avaliamos a integridade de córregos no sudeste brasileiro utilizando o protocolo WHEBIP (Watershed Habitat Evaluation and Biotic Integrity Protocol), que combina informações sobre a cobertura de vegetação ripária, geomorfologia, cobertura da terra e atividades humanas para avaliar as características físicas da sub-bacia e estimar a integridade de córregos. Comparamos esse protocolo com o protocolo RCE (Riparian, Channel and Environmental), já bastante utilizado em regiões tropicais, para avaliação física direta dos córregos. Como medida da integridade funcional dos córregos, estimamos a taxa de decomposição foliar, importante processo nos sistemas lóticos. Além disso, triamos e identificamos os macroinvertebrados que colonizaram as folhas referentes ao 2º e ao 28º dias do experimento de decomposição e calculamos métricas de qualidade ambiental relacionadas às comunidades desses organismos, para testar sua relação com o WHEBIP. Os protocolos WHEBIP e RCE foram significativamente correlacionados entre si, havendo maior diferenciação entre os córregos principalmente quando o RCE foi alto. Possivelmente o WHEBIP, por incorporar variáveis espaciais em uma escala maior na paisagem, diferencia melhor esses córregos. Nenhum dos protocolos testados apresentou correlação com as taxas de decomposição. No entanto, ao calcularmos a variação das taxas de decomposição (erro padrão), observamos uma relação positiva com o protocolo WHEBIP. Assim, agrupamos as métricas do protocolo WHEBIP em uma Análise de Componentes Principais (PCA), observando tendência a uma correlação significativa entre a variação das taxas de decomposição e o primeiro Eixo da PCA, o que indica que o aumento da cobertura florestal na microbacia poderia reduzir a variação nas taxas de decomposição foliar nos córregos. O WHEBIP e o RCE não apresentaram correlações com as métricas de qualidade ambiental relacionadas às comunidades de macroinvertebrados. Mas ao testarmos a hipótese de que os maiores valores do WHEBIP diminuiriam a variação das taxas de decomposição devido a maior estabilidade das comunidades de macroinvertebrados, encontramos uma correlação significativa ao retirarmos um dos córregos das análises. Esse córrego diferenciava-se bastante do restante, pois mesmo obtendo baixo valor no protocolo WHEBIP, apresentou uma baixa diferenciação entre as comunidades, devido à dominância de alguns táxons nos dias analisados. Este é o primeiro trabalho para os trópicos que relaciona a variação nas taxas de decomposição foliar nos córregos e a cobertura florestal das microbacias em que estão inseridos. Nossos resultados sugerem que o protocolo WHEBIP pode ser utilizado para avaliar a integridade de córregos em regiões tropicais. Esse protocolo apresentou relações significativas com a variação nas taxas de decomposição, que pode vir a ser uma métrica interessante para o uso em monitoramento, e com a estabilidade da comunidade de macroinvertebrados, que é maior em córregos menos impactados, conforme sugerido por outros estudos.
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ALENCAR, DONIZETE A. de. "Avaliacao de integridade de revestimentos de combustiveis de reatores de pesquisa e teste de materiais utilizando o ensaio de correntes parasitas." reponame:Repositório Institucional do IPEN, 2004. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11236.

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Tese (Doutoramento)
IPEN/T
Instituto de Pesquisas Energeticas e Nucleares - IPEN/CNEN-SP
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Emer, Maria Claudia Figueiredo Pereira. "Abordagem de teste baseada em defeitos para esquemas de dados." [s.n.], 2007. http://repositorio.unicamp.br/jspui/handle/REPOSIP/261002.

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Orientadores: Mario Jino, Silvia Regina Vergilio
Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia Eletrica e de Computação
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Resumo: Dados são manipulados em várias aplicações de software envolvendo operações críticas. Em tais aplicações assegurar a qualidade dos dados manipulados é fundamental. Esquemas de dados definem a estrutura lógica e os relacionamentos entre os dados. O teste de esquemas por meio de abordagens, critérios e ferramentas de teste específicos é uma forma pouco explorada de assegurar a qualidade de dados definidos por esquemas. Este trabalho propõe uma abordagem de teste baseada em classes de defeitos comumente identificados em esquemas de dados. Um metamodelo de dados é definido para especificar os esquemas que podem ser testados e as restrições aos dados nos esquemas. Defeitos possíveis de serem revelados são os relacionados à definição incorreta ou ausente de restrições aos dados no esquema. A abordagem inclui a geração automática de um conjunto de teste que contém instâncias de dados e consultas a essas instâncias; as instâncias de dados e as consultas são geradas de acordo com padrões definidos em cada classe de defeito. Experimentos nos contextos de aplicações Web e de base de dados foram realizados para ilustrar a aplicação da abordagem
Abstract: Data are used in several software applications involving critical operations. In such applications to ensure the quality of the manipulated data is fundamental. Data schemas define the logical structure and the relationships among data. Testing schemas by means of specific testing approaches, criteria and tools has not been explored adequately as a way to ensure the quality of data defined by schemas. This work proposes a testing approach based on fault classes usually identified in data schemas. A data metamodel is defined to specify the schemas that can be tested and the constraints to the data in schemas. This testing approach provides means for revealing faults related to incorrect or absent definition of constraints for the data in the schema. The approach includes the automatic generation of a test set which contains data instances and queries to these instances; the data instances and queries are generated according to patterns defined in each fault class. Experiments in the contexts of Web and database applications were carried out to illustrate the testing approach application
Doutorado
Engenharia de Computação
Doutor em Engenharia Elétrica
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36

Savvulidi, Filipp. "Metody uchování spermatu trubců včely medonosné: testování kvality uchovávaných spermií pomocí průtokové cytometrie." Master's thesis, Česká zemědělská univerzita v Praze, 2016. http://www.nusl.cz/ntk/nusl-258335.

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Assessment of semen quality (sperm viability) is an essential for the efficient honeybee semen storage. The motility of spermatozoa is not the ultimate parameter of sperm viability. Instead, the viability of spermatozoa is assessed by testing their structural or functional plasma membrane integrity. These assays are based primarily on the technique of microscopy evaluation of either fluorescent DNA dyes or hypo-osmotic "tail-coiling" reaction of spermatozoa. However, the technique of microscopy evaluation is time-consuming, subjective and often is not accurate. On the other hand, the technique of flow cytometry is rapid, objective and precise. Nowadays, this technique is affordable for many institutions, as the price of "benchtop" flow cytometer is relatively low. To best of our knowledge, there is currently no flow cytometry assay available for evaluation of functional integrity of honeybee spermatozoa. Here we report the establishing of novel flow cytometry assay for simultaneous evaluation of structural and functional plasma membrane integrity. DRAQ7, the new fluorescent DNA dye was used to test the structural integrity of plasma membranes. The hypo-osmotic "tail-coiling" reaction was used for flow cytometric assessment of functional integrity of spermatozoa plasma membranes. The combination of both is a valuable tool for rapid and precise evaluation of sperm viability in honey bees.
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37

Brink, Lize. "An investigation into the weld integrity of the head–to–skirt junction on tall distillation columns / L. Brink." Thesis, North-West University, 2010. http://hdl.handle.net/10394/4877.

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This study addresses the fatigue life of the head–to–skirt welds of tall distillation columns. Fatigue tests were done on two types of weld geometries which approximate the head–toskirt configurations. From the fatigue tests it was determined that the fatigue life of the experimental samples can be substantially improved by applying weld build–up between the head and the skirt. The expected fatigue life of the test samples was determined by way of calculation employing the so called Nominal–Stress–Approach, the Effective–Notch–Stress–Approach and the Stress–Life–Approach. For both the Nominal–Stress–Approach and the Effective–Notch–Stress–Approach the predicted fatigue life was found to be overly conservative compared to the experimental results. The Stress–Life–Approach predicted the fatigue life to within a factor of 1.3 for both the geometries under investigation when displacements due to welding are taken into account. If displacements due to welding is omitted this factor is increased, for the geometry without weld build–up, to 2. For the geometry with weld build–up the factor remains 1.3.
Thesis (M.Ing. (Mechanical Engineering))--North-West University, Potchefstroom Campus, 2011.
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38

Johansson, Michael. "Internet of things security in healthcare : A test-suite and standard review." Thesis, Linnéuniversitetet, Institutionen för datavetenskap och medieteknik (DM), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-77138.

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Internet of things is getting more and more popular in healthcare as it comes with benefits that help with efficiency in saving lives and reduce its cost, but it also presents a new attack vector for an attacker to steal or manipulate information sent between them. This report will focus on three properties in the definition of security, confidentiality, integrity and access control. The report will look into what challenges there is in healthcare IoT today through a literature review and from those challenges look into what could minimise these challenges before a device gets into production. The report found that the lack of standardisation has lead to errors that could be easily prevented by following a guideline of tests as those from the European Union Agency for Network and Information Security, or by running a penetration test with the tools brought up in the report on the device to see what vulnerabilities are present.
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39

Morgan, Benoît. "Protection des systèmes informatiques vis-à-vis des malveillances : un hyperviseur de sécurité assisté par le matériel." Thesis, Toulouse, INSA, 2016. http://www.theses.fr/2016ISAT0026/document.

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L'utilisation des systèmes informatiques est aujourd'hui en pleine évolution. Le modèle classique qui consiste à associer à chaque utilisateur une machine physique qu'il possède et dont il va exploiter les ressources devient de plus en plus obsolète. Aujourd'hui, les ressources informatiques que l'on utilise peuvent être distribuées n'importe où dans l'Internet et les postes de travail du quotidien ne sont plus systématiquement des machines réelles. Cette constatation met en avant deux phénomènes importants qui sont à l'origine de l'évolution de notre utilisation de l'informatique : le Cloud computing et la virtualisation. Le Cloud computing (ou informatique en nuage en français) permet à un utilisateur d'exploiter des ressources informatiques, de granularités potentiellement très différentes, pendant une durée variable, qui sont à disposition dans un nuage de ressources. L'utilisation de ces ressources est ensuite facturée à l'utilisateur. Ce modèle peut être bien sûr avantageux pour une entreprise qui peut s'appuyer sur des ressources informatiques potentiellement illimitées, qu'elle n'a pas nécessairement à administrer et gérer elle-même. Elle peut ainsi en tirer un gain de productivité et un gain financier. Du point de vue du propriétaire des machines physiques, le gain financier lié à la location des puissances de calcul est accentué par une maximisation de l'exploitation de ces machines par différents clients.L'informatique en nuage doit donc pouvoir s'adapter à la demande et facilement se reconfigurer. Une manière d'atteindre ces objectifs nécessite notamment l'utilisation de machines virtuelles et des techniques de virtualisation associées. Même si la virtualisation de ressources informatiques n'est pas née avec le Cloud, l'avènement du Cloud a considérablement augmenté son utilisation. L'ensemble des fournisseurs d'informatique en nuage s'appuient aujourd'hui sur des machines virtuelles, qui sont beaucoup plus facilement déployables et migrables que des machines réelles.Ainsi, s'il est indéniable que l'utilisation de la virtualisation apporte un véritable intérêt pour l'informatique d'aujourd'hui, il est par ailleurs évident que sa mise en œuvre ajoute une complexité aux systèmes informatiques, complexité à la fois logicielle (gestionnaire de machines virtuelles) et matérielle (nouveaux mécanismes d'assistance à la virtualisation intégrés dans les processeurs). A partir de ce constat, il est légitime de se poser la question de la sécurité informatique dans ce contexte où l'architecture des processeurs devient de plus en plus complexe, avec des modes de plus en plus privilégiés. Etant donné la complexité des systèmes informatiques, l'exploitation de vulnérabilités présentes dans les couches privilégiées ne risque-t-elle pas d'être très sérieuse pour le système global ? Étant donné la présence de plusieurs machines virtuelles, qui ne se font pas mutuellement confiance, au sein d'une même machine physique, est-il possible que l'exploitation d'une vulnérabilité soit réalisée par une machine virtuelle compromise ? N'est-il pas nécessaire d'envisager de nouvelles architectures de sécurité prenant en compte ces risques ?C'est à ces questions que cette thèse propose de répondre. En particulier, nous présentons un panorama des différents problèmes de sécurité dans des environnements virtualisés et des architectures matérielles actuelles. A partir de ce panorama, nous proposons dans nos travaux une architecture originale permettant de s'assurer de l'intégrité d'un logiciel s'exécutant sur un système informatique, quel que soit son niveau de privilège. Cette architecture est basée sur une utilisation mixte de logiciel (un hyperviseur de sécurité développé par nos soins, s'exécutant sur le processeur) et de matériel (un périphérique de confiance, autonome, que nous avons également développé)
Computer system are nowadays evolving quickly. The classical model which consists in associating a physical machine to every users is becoming obsolete. Today, computer resources we are using can be distributed any place on the Internet and usual workstations are not systematically a physical machine anymore. This fact is enlightening two important phenomenons which are leading the evolution of the usage we make of computers: the Cloud computing and hardware virtualization. The cloud computing enable users to exploit computers resources, with a fine grained granularity, with a non-predefined amount of time, which are available into a cloud of resources. The resource usage is then financially charged to the user. This model can be obviously profitable for a company which wants to lean on a potentially unlimited amount of resources, without administrating and managing it. A company can thereby increase its productivity and furthermore save money. From the physical machine owner point of view, the financial gain related to the leasing of computing power is multiplied by the optimization of machine usage by different clients. The cloud computing must be able to adapt quickly to a fluctuating demand a being able to reconfigure itself quickly. One way to reach these goals is dependant of the usage of virtual machines and the associated virtualization techniques. Even if computer resource virtualization has not been introduced by the cloud, the arrival of the cloud it substantially increased its usage. Nowadays, each cloud provider is using virtual machines, which are much more deployable and movable than physical machines. Virtualization of computer resources was before essentially based on software techniques. But the increasing usage of virtual machines, in particular in the cloud computing, leads the microprocessor manufacturers to include virtualization hardware assistance mechanisms. Theses hardware extensions enable on the one hand to make virtualization process easier et on the other hand earn performances. Thus, some technologies have been created, such as Intel VT-x and VT-d or AMD-V by AMD and virtualization extensions by ARM. Besides, virtualization process needs the implementation of extra functionalities, to be able to manage the different virtual machine, schedule them, isolate and share hardware resources like memory and peripherals. These different functionalities are in general handled by a virtual machine manager, whose work can be more or less eased by the characteristics of the processor on which it is executing.In general, these technologies are introducing new execution modes on the processors, more and more privileged and complex.Thus, even if we can see that virtualization is a real interest for modern computer science, it is either clear that its implementation is adding complexity to computer systems, at the same time software and hardwarecomplexity. From this observation, it is legitimate do ask the question about computer security in this context where the architecture of processors is becoming more and more complex, with more and more privileged execution modes. Given the presence of multiple virtual machine, which do not trust each other, in the same physical machine, is it possible that the exploitation of one vulnerability be carried out by a compromised virtual machine ? Isn't it necessary to consider new security architectures taking these risks into account?This thesis is trying to answer to these questions. In particular, we are introducing state of the art security issues in virtualized environment of modern architectures. Starting from this work, we are proposing an originalarchitecture ensuring the integrity of a software being executed on a computer system, regardless its privilege level. This architecture is both using software, a security hypervisor, and hardware, a trusted peripheral, we have both designed and implemented
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40

Piva, Filippo. "Soluzioni digitali e analogiche per la garanzia di sicurezza in sottosistemi critici ferroviari." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2019.

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Il trasporto ferroviario evolve verso scenari caratterizzati da convogli che viaggiano sempre più ravvicinati e a velocità crescente, il che richiede standard di sicurezza sempre più elevati. Rendere più sicuri treni che viaggiano a distanze ridotte significa poterli localizzare con precisione, cosa che oggi viene fatta anche con soluzioni che si basano sul principio della odometria. Con lo sguardo rivolto al futuro, Rete Ferroviaria Italiana e Arces stanno sviluppando un nuovo sistema di localizzazione odometrica. Questa tesi ha l’obiettivo di studiare una soluzione che assicuri al percorso dei dati del sottosistema di odometria, dal sensore all’elaborazione digitale, una Probability of Failure per Hour non inferiore a 10^-9. Per realizzarlo è stato necessario assicurare l’integrità di una sezione analogica rispetto ai guasti di tipo stuck-at. Sono state quindi studiate le dinamiche di guasto, calcolato il MTBF e infine sono stati pensati stimoli di test in ingresso con controllo delle uscite, pilotati da una sezione digitale. La difficoltà principale è stata rendere trasparenti gli stimoli di test alla logica di elaborazione odometrica, in modo da non compromettere i segnali vitali. Inoltre è stato necessario controllare l’assenza di anomalie nel sensore e nel cavo di trasmissione che lo collega alla sezione analogica, attraverso la misura di corrente assorbita dall’alimentazione. Per farlo è stato progettato un circuito per le misure di corrente ed è stata programmata la sezione digitale per digitalizzare e verificare le misure. Infine è stata redatta la documentazione formale con la descrizione delle scelte progettuali e dei collaudi effettuati in laboratorio, al fine di ottenere la certificazione di sicurezza SIL4, la più alta possibile, come previsto da RFI. L’architettura della sezione digitale in cui si è lavorato era mista, comprendente FPGA e MCU. L’innovazione del progetto risiede nel far eseguire quante più operazioni possibile alla logica programmabile.
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41

Gregori, Alberto. "Synthesis of Conjugated Polymers and Adhesive Properties of Thin Films in OPV Devices." Thesis, Pau, 2015. http://www.theses.fr/2015PAUU3028/document.

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La production d’énergie avec des cellules photovoltaïques organiques (OPV) est une des applications les plus prometteuses des semi-conducteurs organiques, en raison de leur compatibilité avec les substrats flexibles permettant des produits légers, peu chers et décoratifs. Pendant longtemps, poly(3-hexylthiophène) (P3HT) a été le polymère de choix dans l’OPV combiné au [6,6]-phényl-C61-butanoate de méthyle (PC61BM) comme accepteur. Toutefois, des recherches récentes ont porté sur des polymères avec meilleures absorption et processabilité, qui peuvent assurer des rendements et des durées de vie plus élevés. Des rendements de conversion en puissance (PCE) au-dessus de 11% ont récemment été démontrés. Cette thèse rapporte sur la synthèse et la caractérisation de deux séries de polymères dits à faible bande interdite, LBGs "push-pull" (ou donneur-accepteur), constitués de l'unité donneuse 4,4-bis(2-ethylhexyl)-5,5'-dithieno[3,2-b:2',3'-d]silole (DTS) combinée au 3,6-dithiophén-2-yl-2,5-dihydro-pyrrolo[3,4-c]pyrrole-1,4-dione (DPP) ou au 5,7-di(thiényl)thiéno[3,4-b]pyrazines (DTP), comme unité acceptrice. Toutes les molécules et les polymères ont été caractérisés chimiquement et leur propriétés optoelectroniques, morphologiques et photovoltaïques ont été determinées. La série DTS-DPP a été choisie parce qu'elle est représentative d'un grand nombre de polymères LBG et a fourni un modèle facilement accessible pour évaluer l'importance de la chaîne latérale utilisée sur leur propriétés optoélectroniques et thermiques. Les premières études sur les dispositifs à base de DTS-DPP:PC61BM ont été menées, pour déterminer les propriétés photovoltaïques. Le meilleur dispositif permet d’obtenir un PCE de 1,7% avec JSC de 5,9 mA cm-2, VOC de 0,54 V et FF de 0,58. La série DTS-DTP a été choisie pour la stabilité chimique élevée des deux unités et pour la facilité de substitution des groupes latéraux. La polymérisation a partiellement abouti, en donnant seulement des oligomères. La caractérisation chimique a pu être effectuée, mais leur application dans l’OPV n'a pas été explorée. En termes de stabilité, les mécanismes de défaillance électrique des dispositifs OPV ont été étudiés, montrant une méconnaissance de leur stabilité mécanique. Les contraintes caractéristiques de chaque couche mince présentes dans les cellules solaires organiques constituent la force motrice à l’origine de la délamination des interfaces faibles ou même leur decohésion, causant une perte de l'intégrité et des performances du dispositif. Une technique pour sonder les couches ou les interfaces fragiles dans les cellules solaires polymère:fullerene est présentée. Elle a été développée par l'établissement d'un nouveau set-up pour le test pull-off, développé en utilisant un dispositif à géométrie inverse, de structure verre/ITO/ZnO/P3HT:PC61BM/PEDOT:PSS/Ag. Les dispositifs délaminés ont montré que le point le plus faible est localisé à l'interface AL/HTL, en bon accord avec la littérature. La technique a été étendue en variant les deux couches sensibles, en utilisant differents polymères LBG pour l’AL (PSBTBT et PDTSTzTz) en combinaison avec deux formulations de PEDOT:PSS, CleviosTM HTL Solar à base d'eau et un nouveau HTL Solar 2 à base de solvant organique. Une différence entre la contrainte à la rupture des dispositifs avec différentes combinaisons de AL et HTL est visible, suggérant différents chemins de fracture, tel que confirmé par la caractérisation de surface et qui pourrait être corrélée avec la différence de comportement de la couche active avec les deux formulations de PEDOT:PSS. Une autre voie adoptée, a été d’introduire une couche d’interface de copolymère à blocs amphiphile afin d'améliorer la compatibilité des deux couches. Cette stratégie n'a pas abouti et la nouvelle architecture présente une adhésion réduite. La poursuite de l’amélioration des procédés de fabrication de ces dispositifs pourrait faire de cette nouvelle architecture, une alternative viable
Organic photovoltaic (OPV) devices are one of the most promising applications of organic semiconductors due to their compatibility with flexible plastic substrates resulting in light weight, inexpensive and decorative products. For a long time poly(3-hexylthiophene) (P3HT) has been the polymer of choice in OPV devices in combination with [6,6]-phenyl-C61-butyric acid methylester (PC61BM) as acceptor. However, recent research has focused on polymers with improved absorbance and processability that can ensure higher efficiencies and longer lifetimes (Low BandGap polymers (LBGs)). This has been fully demonstrated with a power conversion efficiency (PCE) above 11%. This thesis reports synthesis and characterization of two series of so-called “push-pull” (or donor-acceptor) LBGs based on the donor unit 4,4′-bis(2-ethylhexyl)-5,5’-dithieno[3,2-b:2′,3′-d]silole (DTS) and either 3,6-dithiophen-2-yl-2, 5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione (DPP) or 5,7-di(thienyl)thieno[3,4-b]pyrazines (DTP), as acceptor unit. All π-conjugated molecules and polymers were characterized by chemical investigation and their optoelectronic, morphological, and photovoltaic properties are reported. The DTS-DPP series was chosen because representative of a large number of LBG polymers and provided an easily accessible and useful template to discover the importance of the type of side-chain used on the polymer optoelectronic and thermal properties. First studies on DTS-DPP:PC61BM devices have been conducted, in order to investigate any effect on their photovoltaic properties. The best device obtained had a PCE of 1.7% with JSC of 5.9 mA•cm-2, VOC of 0.54 V and FF of 0.58. The DTS-DTP series was chosen for the high stability of the two units and for the ease of substitution of the side-groups. The synthesis was partially successful and only oligomers were obtained. Nonetheless, chemical characterization was performed but their application in OPV was not explored. In terms of device stability, the electrical failure mechanisms in OPV devices have been investigated, while little is known about their mechanical stability. The characteristic thin film stresses of each layer present in organic solar cells, in combination with other possible fabrication, handling and operational stresses, provide the mechanical driving force for delamination of weak interfaces or even their de-cohesion, leading to a loss of device integrity and performance. A technique to probe weak layers or interfaces in inverted polymer:fullerene solar cells is presented. It was developed by establishing a new set-up for the pull-off test. The technique was developed using inverted device, with the structure glass/ITO/ZnO/P3HT:PC61BM/PEDOT:PSS/Ag. The delaminated devices showed that the weakest point was localized at the active layer/hole transporting layer interface, in good agreement with the literature. The technique was extended varying both sensitive layers, using different p-type low bandgap (co)polymers for the active layer (PSBTBT and PDTSTzTz) in combination with two different PEDOT:PSS formulations, the water based CleviosTM HTL Solar and a new organic solvent based HTL Solar 2. The half-devices produced upon destructive testing have been characterized by contact angle measurement, AFM and XPS to locate the fracture point. A difference in the stress at break for devices made with different combinations of active and hole transporting layers is visible, suggesting different fracture paths, as confirmed by surface characterization and could be correlated to the different behavior of the active layer with the two PEDOT:PSS formulations. Another solution adopted, it had been the introduction of amphiphilic block-copolymer interlayer to enhance the compatibility of the two layers. This strategy was not successful and the new architecture showed reduced adhesion strength. Further development of device processing could make this new architecture a viable alternative
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42

Lodi, Chiara. "Modelling the energy dynamics of ventilated photovoltaic facades using stochastic differential equations in a monitored Test Reference Environment." Doctoral thesis, Universitat de Lleida, 2012. http://hdl.handle.net/10803/84167.

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L'objectiu general d'aquest treball és contribuir a l'avaluació de la transferència de l'energia en règim dinàmic de sistemes Fotovoltaics de doble pell Integrats en Edificis (EIFV) amb ventilació forçada sota condicions climàtiques exteriors reals. Per tant, un dels objectius d'aquest treball de recerca va consistir a recol.lectar dades experimentals sota condicions externes reals amb el “Test Reference Environment” (TRE) al Parc Científic i Tecnològic Agroalimentari de Lleida (PCiTAL). Es va dur a terme una llarga campanya de mesures on es van realitzar diversos experiments, amb diferents inclinacions i règims de ventilació. Un altre objectiu va ser estimar paràmetres físics desconeguts mitjançant l'ús de models d'identificació. Per aconseguir aquest objectiu, diversos models de caixa grisa estocàstics es van desenvolupar. Finalment, a partir de l'experiència adquirida durant el treball experimental, d'anàlisi i de modelatge, s'ha proposat la definició d'un entorn de prova “Test Reference Environment” estandarditzat per a les aplicacions de EIFV de doble pell.
El objetivo general de este trabajo es contribuir a la evaluación de la transferencia de la energía en régimen dinámico de sistemas de doble piel FotoVoltaicos Integrados en Edificios (EIFV) con ventilación forzada bajo condiciones climáticas exteriores reales. Por lo tanto, uno de los objetivos de este trabajo de investigación consistió en recolectar datos experimentales bajo condiciones externas reales con el “Test Reference Environment” (TRE) en el Parque Científico y Tecnológico Agroalimentario de Lleida (PCiTAL). Se llevó a cabo una larga campaña de medidas donde se realizaron varios experimentos, con diferentes inclinaciones y regímenes de ventilación. Otro objetivo fue estimar parámetros físicos desconocidos mediante el uso de modelos de identificación. Para lograr este objetivo, varios modelos de caja gris estocásticos se desarrollaron. Por último, a partir de la experiencia adquirida durante el trabajo experimental, de análisis y de modelación, se ha propuesto la definición de un entorno de prueba “Test Reference Environment” estandarizado para las aplicaciones de EIFV de doble piel.
The general aim of this work is to contribute to the energy dynamics assessment of mechanically ventilated double skin Building Integrated PhotoVoltaic (BIPV) systems under real outdoor weather conditions. Therefore, one of the objectives of this research work has consisted in collecting experimental data under real outdoor conditions in the Test Reference Environment (TRE) at the Lleida Agri-food Science and Technology Park (PCiTal). An extensive monitoring campaign has been carried out and several experiments, at different inclinations and ventilation regimes, have been performed. Another goal was to estimate unknown physical parameters by using identification models. To achieve this goal, several stochastic grey-box models have been developed. Finally, from the experience gained during the experimental, analysis and modelling work, the definition of a standardized set-up for a Test Reference Environment for double skin applications of BIPV has been proposed.
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43

Maggi, Silvio. "L’italiano per studenti universitari e allievi delle EOI ispanofoni: un test sull’apprendimento di alcuni atti comunicativi con il metodo dei DCT." Doctoral thesis, Universitat de Barcelona, 2012. http://hdl.handle.net/10803/84099.

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Questa ricerca si propone di chiarire alcuni aspetti dell’insegnamento e dell’apprendimento di alcune strategie comunicative in una Lingua straniera (LS) simile: i nostri informanti sono studenti ispanofoni provenienti dalla Spagna e sono tutti di livello B1 del Quadro Comune Europeo di Riferimento per le Lingue. Tutti studiano italiano come LS. Alcuni di loro studiano nelle università del paese e gli altri nelle scuole ufficiali di lingue (EOI). Cerchiamo di osservare il livello di consapevolezza pragmatica raggiunto da questi informanti su alcuni atti comunicativi nella lingua straniera che studiano, tramite un test effettuauto con questionari comunicativi. Gli atti comunicativi osservati sono le richieste, le giustificazioni e le chiusure di conversazione in una prima fase pilota e le giustificazioni e chiusure di conversazione nella fase principale dello studio. L'obiettivo della ricerca è quello di vedere se l'affinità linguistica può aiutare gli informanti che partecipano al test, anche se sappiamo che le funzioni comunicative sono sempre specifiche nelle diverse culture, nonostante la forte somiglianza tra spagnolo e italiano. Inoltre, cerchiamo di dimostrare la validità dello strumento metodologico che utilizziamo per raccogliere i dati di ricerca. Il DCT ("Discorse completion test ") sono stati utilizzati più volte per raccogliere dati sulla pragmatica dell’interlingua e dell’intercultura e crediamo che essi rappresentano un valido metodo per la raccolta dei dati in un momento specifico di apprendimento di una LS (in questo caso, a livello B1) per valutare il livello raggiunto in queste funzioni comunicative.Ci proponiamo quindi di scoprire cosa si nasconde in questo settore dell'insegnamento delle LS affini, con l'idea anche di proporre progetti per la realizzazione di libri di testo e altro materiale didattico e di promuovere l'apprendimento dell’italiano da parte degli studenti spagnoli nativi della Spagna. Questo studio cerca anche di fare un confronto tra lo spagnolo e l’italiano nel campo delle richieste e delle giustificazioni, e tenendo conto del fatto che tale lavoro non era stato fatto prima, questa ricerca può chiarire alcune cose in questo settore della pragmatica e rappresentare un punto di partenza per ulteriori studi. I risultati dell’analisi dei dati sono positivi, la maggior parte degli informanti ha fatto registrare prestazioni accettabili nel test e un ricercatore indipendente specializzato in linguistica, ha analizzato i dati e ha convalidato la ricerca con una percentuale molto alta di accordo con noi. Per risultati ancor piu’ definitivi saranno necessari altri studi che utilizzino altri strumenti di raccolta dati, ma questa ricerca gia’ rende chiaro che, nonostante la scarsità di trattamento degli atti comunicativi nei libri di testo, gli studenti spagnoli hanno una buona consapevolezza pragmatica delle formule strategiche necessarie in italiano, e cio’ e’dovuto a una buona somiglianza delle norme sociali che vengono utilizzate nelle due culture.
En esta investigación queremos aclarar unos aspectos de la enseñanza y aprendizaje de las estrategias comunicativas en una LE afín: nuestros informantes son estudiantes hispanohablantes de España, todos son de nivel B1 del marco común europeo de referencia para las lenguas. Todos estudian el italiano. Algunos informantes estudian en universidades del país y otros en Escuelas Oficiales de Idiomas (EOI). Intentamos observar el nivel de conciencia pragmática logrado por estos informantes en unos actos comunicativos en el idioma extranjero afín que estudian, mediante una prueba por medio de cuestionarios comunicativos. Los actos comunicativos que se observan son solicitudes, justificaciones y cierres conversacionales en una fase piloto y las justificaciones y los cierres conversacionales en la fase principal del estudio. El objetivo de la investigación es observar si la afinidad lingüística puede ser de ayuda a los informantes que participan en la prueba, aunque sabemos que las funciones comunicativas son siempre específicas en las diferentes culturas, no obstante la fuerte semejanza lingüística entre español e italiano. Además, intentamos demostrar la validez del instrumento metodológico que utilizamos para recoger los datos de la investigación. Los DCT (“discourse completion test”) se han utilizado muchas veces para la recogida de datos sobre la pragmática de la interlengua y de la intercultura y creemos que representan un método válido para recoger datos en un momento específico del aprendizaje de una LE (en este caso en el nivel B1) para evaluar el nivel logrado en esas funciones comunicativas. Queremos por lo tanto descubrir lo que se esconde en esta área de la didáctica de LE afines con la idea de proponer también proyectos para la realización de libros de textos y otro material para la enseñanza y para favorecer el aprendizaje del italiano por parte de estudiantes nativos de España. Este estudio, además, intenta hacer una comparación entre el español y el italiano en el ámbito de las solicitudes y de las justificaciones, y teniendo en consideración que este tipo de trabajo no se había hecho antes, esta investigación puede aclarar algunas cosas en esta área de la pragmática y hacer de punto de partida para otros estudios. Los resultados del análisis de datos son positivos, la mayoría de los informantes ha realizado prestaciones aceptables en las pruebas y un investigador independiente, especializado en lingüística, ha analizado los datos y convalidado la investigación con un porcentaje muy alto de acuerdo con nosotros. Para resultados mayormente definitivos serán necesarios otros estudios que emplean también otros instrumentos de recogida de datos pero este investigación ya aclara que, no obstante un escaso tratamiento de los actos comunicativos en los libros de texto, los estudiantes españoles saben bastante bien las formulas estratégicas que se requieren en Italiano, debido a una buena semejanza de las normas sociales que se utilizan en las dos culturas.
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44

Lenfeldt, Niklas. "The search for reversibility of Idiopathic normal pressure hydrocephalus : Aspects on intracranial pressure measurments and CSF volume alteration." Doctoral thesis, Umeå universitet, Farmakologi och klinisk neurovetenskap, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1422.

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BACKGROUND: Idiopathic normal pressure hydrocephalus (INPH) is still a syndrome generating more questions than answers. Today, research focuses mainly on two areas: understanding the pathophysiology – especially how the malfunctioning CSF system affects the brain parenchyma – and finding better methods to select patients benefiting from a shunt operation. This thesis targets the aspect of finding better selection methods by investigating the measurability of intracranial pressure via lumbar space, and determining if intraparenchymal measurement of long-term ICP-oscillations (B-waves) could be replaced by short-term measurements of CSF pulse pressure waves via lumbar space. Furthermore, I look into the interaction between the CSF system and the parenchyma itself by investigating how the cortical activity of the brain changes after long-term CSF drainage, and if there is any regress in the suggested ischemia after this intervention. Finally, I examine if the neuronal integrity in the INPH brain is impaired, and if this feature is relevant for the likeliness of improvement after CSF diversion. METHODS: The comparison of intracranial and lumbar pressure was made over a vast pressure interval using our unique CSF infusion technique, and it included ten INPH patients. Pressure was measured via lumbar space and in brain tissue, and the pressures were compared using a general linear model. Short-term lumbar pressure waves were quantified by determining the slope between CSF pulse pressure and mean pressure, defined as the relative pulse pressure coefficient (RPPC). The correlation between RPPC, B-waves and CSF outflow resistance was investigated. In a prospective study, functional MRI was used to assess brain activity before and after long-term CSF drainage of 400 ml of CSF in eleven INPH patients. The functionalities tested included finger movement, memory, and attention. The results were benchmarked against the activity in ten healthy controls to identify the brain areas improving after drainage. The ischemia (Lactate) and neuronal integrity (NAA and Choline) were measured in a similar manner in 16 patients using proton MR spectroscopy, and the improvement of the patients after CSF drainage was based on assessment of their gait. RESULTS: There was excellent agreement between ICP measured in brain tissue and via lumbar space (regression coefficient = 0.98, absolute difference < 1 mm Hg). Adjusting for the separation distance between the measuring devices slightly worsened the agreement, indicating other factors influencing the measured difference as well. RPPC measured via lumbar space significantly correlated to the presence of B-waves, but not to outflow resistance. In the prospective study, controls outperformed patients on clinical tests as well as tasks related to the experiments. Improved behaviour after CSF drainage was found for motor function only, and it was accompanied by increased activation in the supplementary motor area (SMA). No lactate was detected, either before or after CSF drainage. NAA was decreased in INPH patients compared to controls, and the NAA levels were higher in the patients improving after drainage. CONCLUSIONS: ICP can be accurately measured via lumbar space in patients with communicating CSF systems. The close relation between RPPC and B-waves indicates that B-waves are primarily related to intracranial compliance, and that measurement of RPPC via lumbar space could possibly substitute B-wave assessment as selection method for finding suitable patients for shunt surgery. Improvement in motor function after CSF drainage was associated to enhanced activity in SMA, supporting the involvement of the cortico-basal ganglia-thalamo-cortical loop in the pathophysiology of INPH. There was no evidence indicating a widespread low-graded ischemia in INPH; however, there was a neuronal dysfunction in frontal white matter as indicated by the reduced levels of NAA. In addition, the level of neuronal dysfunction was related to the likeliness of improvement after CSF removal, normal levels of NAA predisposing for recovery.
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45

Erraud, Alexandre. "Développement d’un biomarqueur de qualité spermatique chez deux espèces de crevettes Palaemonidae : état des lieux le long du continuum estuaire / littoral de la Seine." Thesis, Normandie, 2018. http://www.theses.fr/2018NORMLH12/document.

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La fitness et a fortiori la survie d'une population dépendent de la stratégie et des performances de reproduction façonnées par son environnement. Par conséquent, les biomarqueurs traduisant une altération de la fonction de reproduction présentent un intérêt particulier. L'atteinte de la fertilité mâle au sein de la faune sauvage a notamment été adressée comme une problématique majeure susceptible de représenter une menace pour le maintien des populations. Toutefois, peu de méthodologies sont aujourd'hui disponibles chez des espèces pertinentes pour aborder cette problématique dans le cadre de programmes de biosurveillance environnementale, notamment chez les crustacés en dépit de leur représentativité au sein du règne animal et de leurs indispensables fonctions au sein des écosystèmes. Dans ce contexte, les présents travaux avaient pour objectif de proposer une ou plusieurs méthodologies basées sur la mesure de marqueurs de fonctionnalité et d'intégrité spermatique chez des crevettes Palaemonidae. Les investigations se sont portées sur deux espèces, une estuarienne, Palaemon longirostris, et une côtière, Palaemon serratus, pour leur complémentarité vis-à-vis du continuum estuaire - littoral. Compte tenu des nombreuses spécificités structurelles et fonctionnelles des spermatozoïdes de crustacés, I nombre de marqueurs transposables vers ces espèces s'est finalement avéré limité. Aussi, après une brève prospection, l'effort de recherche a rapidement été recentré sur la mesure de l'intégrité de l'ADN. Dès lors, la démarche scientifique a été construite de sorte à évaluer, point par point, la pertinence de la méthodologie développée dans une perspective d'application de l'outil dans le cadre de la surveillance environnementale. Une étape préliminaire d'optimisation et de validation méthodologique du test Cornet a démontré que, contrairement à une grande majorité de type spermatique, l'adaptation de ce test sur les spermatozoïdes de Palaemonidae ne nécessite aucune modification particulière du protocole. La dynamique de la réponse biologique en termes d'apparitions, de rémanence et d'effets possibles sur la fitness a été évaluée en conditions contrôlées au laboratoire. Ainsi, des expositions ex vivo et in vivo ont été conduites en utilisant une variété de génotoxiques modèles présentant différents modes d'actions. Les résultats ont attesté de la sensibilité, de la reproductibilité et du caractère intégrateur de la réponse. En revanche, aucun lien entre un ADN spermatique endommagé et une altération du succès de reproduction pré-éclosion n'a pu être établi. Parallèlement, une approche in situ a été conduite en vue de caractériser la valeur basale de la réponse mesurée. Différentes stratégies ont dû être adoptées en fonction des contraintes propres au milieu de vie de chacune des deux espèces. Un référentiel et une valeur seuil, communs aux deux espèces, ont pu être définis, soulignant le potentiel de transférabilité inter-espèces de l'outil. La méthodologie ainsi finalisée, a été éprouvée dans le cadre de plusieurs campagnes de suivi de différentes populations indigènes de l'estuaire et de la baie de Seine en 2015 et 2016. Les résultats se sont révélés très cohérents au regard de la pression de contamination et de la dynamique hydro-sédimentaire de la baie de Seine. En définitive, l'intégrité de l'ADN spermatique chez les Palaemonidae est opérationnelle en l'état pour un déploiement in situ en tant que biomarqueur d'exposition à un stress génotoxique. De futurs études devront néanmoins être conduites (1) pour mieux discerner les implications de ces dommages spermatiques en termes d'impact sur le recrutement des nouvelles cohortes et (2) éprouver la transférabilité de la méthodologie à d'autres espèces de crevettes et sur une plus large échelle géographique
The environment shapes the reproduction's strategy and performance of a population, influencing its fitness and a fortiori its survival. Therefore, biomarkers that alter reproductive functions represent a great interest in ecotoxicology. The reduction of male fertility in wildlife can represent a threat to the population's survival. Moreover, fcw methodologies are available for species that are relevant to address this issue on envimnmental biomonitoring programs, especially for crustaceans, despite their representativeness in the wildlife and their essential functions within ecosysterns. The present work aimed to propose methodologies based on the measurement of functionality and integrity spermatic biomarkers on Palaemonidae shrimps. We studied two species, an estuarine, Palaemon longirostris, and a coastal species. Palaemon serratus. due to their complementaiity on the continuum estuary-littoral ecosystem. Howevcr, crustaceans' sperm has many structuraI and functional characteristics, the number of transposable markers is limited. Thereafter, the research effort was refocused on the measurement of the DNA integrity and this inethod was evaluated for its adequacy for a biomonitoring study. We optitrtized and validate the Cornet assay for the Palaemonidae species, and the dynamic of the biological response in ternis of appearances, persistence, and possible effects on fitness was evaluated under controlled conditions in the laboratoiy. Furthermore, ex-vivo and in-vivo exposures were conducted using genotoxic models with different modes of action. On the one hand, results attested to the sensibility, the reproducibility and the integrating character of the response, on the other hand, no correlation between damaged sperm DNA and an altération of the pre-hatch stage of development was established. In paralIel, an in-situ approach was conducted to characterize the baseline level of the measured response, taking into consideration the specific constraints of each species' habitat. We were able to define a common baseline level and a threshold value for both species, highlighting the potential of the tool for inter-species transferability. This method was tested with native populations from the estuary and from the Seine Bay in 2015 and 20] 6. And, the results proved to be consistent with the contamination pressure and the hydro-sedimentary dynamics of the Seine Bay. Ultimately, the DNA integrity of sperm in Palaemonidae seems to be functional for in-situ deploytnents as a biomarker of exposure to genotoxic stress. Nevertheless, future studies should be conducted (1) to botter discern the implications of this spermatic damage on the recruitment of new cohorts and, (2) to test the transferability of the methodology to other shrimp species and on a wider geographical scale
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Mondelin, Alexandre. "Modélisation de l'intégrité des surfaces usinées : Application au cas du tournage finition de l'acier inoxydable 15-5PH." Phd thesis, Ecole Centrale de Lyon, 2012. http://tel.archives-ouvertes.fr/tel-00838512.

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En usinage, la zone de coupe présente des conditions de température, des cinétiques thermiques, des déformations et des pressions extrêmes. Dans ce contexte, être capable de relier les variations des conditions de coupe (vitesse de coupe, avance, lubrification, usure, outil,...) à l'intégrité de la surface usinée constitue un objectif scientifique majeur. Cette thèse s'intéresse au cas du tournage finition du 15-5PH (acier inoxydable martensitique utilisé, entre autre, pour la fabrication des pièces de rotor d'hélicoptère ainsi que les pompes et les vannes de circuit primaire de centrale nucléaire) et s'inscrit dans le cadre du projet MIFSU (Modélisation de l'Intégrité et de la Fatigue des Surfaces Usinées).Dans un premier temps, le comportement du matériau a été étudié afin d'alimenter les simulations d'usinage. Des essais de dilatométrie libre ont été conduit afin de calibrer les cinétiques d'austénitisation du 15-5PH pour des vitesses de chauffe élevées (jusqu'à 11000 °C/s). Les paramètres du modèle de changement de phase de Leblond ont alors été identifiés. De plus, des essais de compression dynamique (dε/dt allant de 0.01 à 80 /s et ε > 1) ont été réalisés pour calibrer une loi de comportement élasto-plastique aux grandes déformations avec une sensibilité à la vitesse de déformation. Ces essais ont aussi permis de mettre en évidence des phénomènes de recristallisation dynamique et leurs influences sur la contrainte d'écoulement du matériau. Un modèle de recristallisation dynamique a donc également été mis en œuvre.En parallèle, un modèle numérique de prédiction de l'intégrité des surfaces tournées a été construit. Ce modèle repose sur une méthodologie dite " hybride " (développée au cours de la thèse Frédéric Valiorgue pour l'acier AISI 304L) qui consiste à supprimer la modélisation de l'outil de coupe et de la formation du copeau, et à remplacer l'impact thermomécanique de ces derniers sur la surface usinée par des chargements équivalents. Une étape de calibration de ces chargements a donc été réalisée à travers des essais de coupe orthogonale et de frottement (étude de sensibilité des efforts d'usinage, du coefficient de frottement et du coefficient de partage thermique) aux variations des paramètres de coupe.Enfin, les résultats des simulations numériques de tournage portant sur la prédiction des changements de microstructure (austénitisation et recristallisation dynamique) ainsi que des contraintes résiduelles ont été comparés aux résultats issus d'une campagne d'essais de chariotage.
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47

Fenollosa, Artés Felip. "Contribució a l'estudi de la impressió 3D per a la fabricació de models per facilitar l'assaig d'operacions quirúrgiques de tumors." Doctoral thesis, Universitat Politècnica de Catalunya, 2019. http://hdl.handle.net/10803/667421.

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La present tesi doctoral s’ha centrat en el repte d’aconseguir, mitjançant Fabricació Additiva (FA), models per a assaig quirúrgic, sota la premissa que els equips per fer-los haurien de ser accessibles a l’àmbit hospitalari. L’objectiu és facilitar l’extensió de l’ús dels prototips com a eina de preparació d’operacions quirúrgiques, transformant la pràctica mèdica actual de la mateixa manera que en el seu moment ho van fer tecnologies com les que van facilitar l’ús de radiografies. El motiu d’utilitzar FA, en lloc de tecnologies més tradicionals, és la seva capacitat de materialitzar de forma directa les dades digitals obtingudes de l’anatomia del pacient mitjançant sistemes d’escanejat tridimensional, fent possible l’obtenció de models personalitzats. Els resultats es centren en la generació de nou coneixement sobre com aconseguir equipaments d’impressió 3D multimaterials accessibles que permetin l’obtenció de models mimètics respecte als teixits vius. Per facilitar aquesta buscada extensió de la tecnologia, s’ha focalitzat en les tecnologies de codi obert com la Fabricació per Filament Fos (FFF) i similars basades en líquids catalitzables. La recerca s’alinea dins l’activitat de desenvolupament de la FA al CIM UPC, i en aquest àmbit concret amb la col·laboració amb l’Hospital Sant Joan de Déu de Barcelona (HSJD). El primer bloc de la tesi inclou la descripció de l’estat de l’art, detallant les tecnologies existents i la seva aplicació a l’entorn mèdic. S’han establert per primer cop unes bases de caracterització dels teixits vius -sobretot tous- per donar suport a la selecció de materials que els puguin mimetitzar en un procés de FA, a efectes de millorar l’experiència d’assaig dels cirurgians. El caràcter rígid dels materials majoritàriament usats en impressió 3D els fa poc útils per simular tumors i altres referències anatòmiques. De forma successiva, es tracten paràmetres com la densitat, la viscoelasticitat, la caracterització dels materials tous a la indústria, l’estudi del mòdul elàstic de teixits tous i vasos, la duresa d’aquests, i requeriments com l’esterilització dels models. El segon bloc comença explorant la impressió 3D mitjançant FFF. Es classifiquen les variants del procés des del punt de vista de la multimaterialitat, essencial per fer models d’assaig quirúrgic, diferenciant entre solucions multibroquet i de barreja al capçal. S’ha inclòs l’estudi de materials (filaments i líquids) que serien més útils per mimetitzar teixits tous. Es constata com en els líquids, en comparació amb els filaments, la complexitat del treball en processos de FA és més elevada, i es determinen formes d’imprimir materials molt tous. Per acabar, s’exposen sis casos reals de col·laboració amb l’HJSD, una selecció d’aquells en els que el doctorand ha intervingut en els darrers anys. L’origen es troba en la dificultat de l’abordatge d’operacions de resecció de tumors infantils com el neuroblastoma, i a la iniciativa del Dr. Lucas Krauel. Finalment, el Bloc 3 té per objecte explorar nombrosos conceptes (fins a 8), activitat completada al llarg dels darrers cinc anys amb el suport dels mitjans del CIM UPC i de l’activitat associada a treballs finals d’estudis d’estudiants de la UPC, arribant-se a materialitzar equipaments experimentals per validar-los. La recerca ampla i sistemàtica al respecte fa que s’estigui més a prop de disposar d’una solució d’impressió 3D multimaterial de sobretaula. Es determina que la millor via de progrés és la de disposar d’una pluralitat de capçals independents a fi de capacitar la impressora 3D per integrar diversos conceptes estudiats, materialitzant-se una possible solució. Cloent la tesi, es planteja com seria un equipament d’impressió 3D per a models d’assaig quirúrgic, a fi de servir de base per a futurs desenvolupaments.
La presente tesis doctoral se ha centrado en el reto de conseguir, mediante Fabricación Aditiva (FA), modelos para ensayo quirúrgico, bajo la premisa que los equipos para obtenerlos tendrían que ser accesibles al ámbito hospitalario. El objetivo es facilitar la extensión del uso de modelos como herramienta de preparación de operaciones quirúrgicas, transformando la práctica médica actual de la misma manera que, en su momento, lo hicieron tecnologías como las que facilitaron el uso de radiografías. El motivo de utilizar FA, en lugar de tecnologías más tradicionales, es su capacidad de materializar de forma directa los datos digitales obtenidos de la anatomía del paciente mediante sistemas de escaneado tridimensional, haciendo posible la obtención de modelos personalizados. Los resultados se centran en la generación de nuevo conocimiento para conseguir equipamientos de impresión 3D multimateriales accesibles que permitan la obtención de modelos miméticos respecto a los tejidos vivos. Para facilitar la buscada extensión de la tecnología, se ha focalizado en las tecnologías de código abierto como la Fabricación por Hilo Fundido (FFF) y similares basadas en líquidos catalizables. Esta investigación se alinea dentro de la actividad de desarrollo de la FA en el CIM UPC, y en este ámbito concreto con la colaboración con el Hospital Sant Joan de Déu de Barcelona (HSJD). El primer bloque de la tesis incluye la descripción del estado del arte, detallando las tecnologías existentes y su aplicación al entorno médico. Se han establecido por primera vez unas bases de caracterización de los tejidos vivos – principalmente blandos – para dar apoyo a la selección de materiales que los puedan mimetizar en un proceso de FA, a efectos de mejorar la experiencia de ensayo de los cirujanos. El carácter rígido de los materiales mayoritariamente usados en impresión 3D los hace poco útiles para simular tumores y otras referencias anatómicas. De forma sucesiva, se tratan parámetros como la densidad, la viscoelasticidad, la caracterización de materiales blandos en la industria, el estudio del módulo elástico de tejidos blandos y vasos, la dureza de los mismos, y requerimientos como la esterilización de los modelos. El segundo bloque empieza explorando la impresión 3D mediante FFF. Se clasifican las variantes del proceso desde el punto de vista de la multimaterialidad, esencial para hacer modelos de ensayo quirúrgico, diferenciando entre soluciones multiboquilla y de mezcla en el cabezal. Se ha incluido el estudio de materiales (filamentos y líquidos) que serían más útiles para mimetizar tejidos blandos. Se constata como en los líquidos, en comparación con los filamentos, la complejidad del trabajo en procesos de FA es más elevada, y se determinan formas de imprimir materiales muy blandos. Para acabar, se exponen seis casos reales de colaboración con el HJSD, una selección de aquellos en los que el doctorando ha intervenido en los últimos años. El origen se encuentra en la dificultad del abordaje de operaciones de resección de tumores infantiles como el neuroblastoma, y en la iniciativa del Dr. Lucas Krauel. Finalmente, el Bloque 3 desarrolla numerosos conceptos (hasta 8), actividad completada a lo largo de los últimos cinco años con el apoyo de los medios del CIM UPC y de la actividad asociada a trabajos finales de estudios de estudiantes de la UPC, llegándose a materializar equipamientos experimentales para validarlos. La investigación amplia y sistemática al respecto hace que se esté más cerca de disponer de una solución de impresión 3D multimaterial de sobremesa. Se determina que la mejor vía de progreso es la de disponer de una pluralidad de cabezales independientes, a fin de capacitar la impresora 3D para integrar diversos conceptos estudiados, materializándose una posible solución. Para cerrar la tesis, se plantea cómo sería un equipamiento de impresión 3D para modelos de ensayo quirúrgico, a fin de servir de base para futuros desarrollos.
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48

Příhodová, Tereza. "Měření integrity v klinických podmínkách a v situaci výběru. Využití testu integrity v klinické praxi a psychologii práce." Doctoral thesis, 2021. http://www.nusl.cz/ntk/nusl-445979.

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Univerzita Karlova 1. lékařská fakulta Studijní program: Psychologie Studijní obor: Lékařská psychologie a psychopatologie Tereza Příhodová, M.A. Měření integrity v klinických podmínkách a v situaci výběru Využití testu integrity v klinické praxi a psychologii práce Integrity measures under clinical conditions and in selection situations The use of integrity test in clinical practice and at work psychology Disertační práce - abstrakt v anglickém jazyce Vedoucí závěrečné práce/Školitel: doc. PhDr. Marek Preiss, Ph.D. Konzultant: PhDr. et PaedDr. Pavel Harsa, Ph.D. et Ph.D. Praha, 2021 ABSTRACT Integrity is a psychological and philosophical construct, which is closely related to the concepts of moral psychology. In different psychological disciplines it is often associated with related constructs including conscientiousness, virtue, honesty or emotional stability. In Czech psychological and psychiatric practice integrity is a variable, which is commonly not measured and evaluated as a personal asset, mainly due to the fact that there is a lack of proper instruments, which would be accessible to clinicians or researchers. The main goal of this dissertation thesis was to introduce newly developed integrity test, which is applicable in clinical and in non-clinical settings. Thus, this thesis summarizes the...
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49

Reslová, Gabriela. "Úloha signální dráhy integrity buněčné stěny při morfogenezi kvasinkových kolonií." Master's thesis, 2013. http://www.nusl.cz/ntk/nusl-321105.

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In the yeast Saccharomyces cerevisiae, stress on the cell wall is caused by various external influences (e.g. exposure to chemicals, oxidative stress, osmotic changes, pH changes or heat shock) which trigger the cell wall integrity signalling pathway (CWI). The aim of my work was to investigate the effect of the CWI pathway on yeast colony morphogenesis. Using strains with deletions in genes of the CWI pathway derived from two parental strains BR-F-Flo11p-GFP and PORT, I have found that differences in genetic background influences the process and activation of this pathway. Among the strains derived from BR-F-Flo11p-GFP, only the strain with the deletion of MID2 affects the appearance of colonies. MID2 encodes a cell-surface sensor of CWI pathway. In all deletion strains derived from PORT, the disruption of the CWI pathway causes a slower development of colonies growing on glycerol medium supplemented with 0,05 mM selenate inducing fluffy colony morphology. The largest effect has deletion of gene MTL1 which also encodes a cell-surface sensor with homology to Mid2. I have confirmed that strains with deletions in genes of CWI pathway have altered sensitivity to inhibitors disrupting cell wall integrity (Calcofluor white, Congo red, zymolyase). By means of zymolyase assay, I have confirmed the...
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50

Salzerová, Aneta. "Měření integrity osobnosti - test konzistence odpovědí." Master's thesis, 2019. http://www.nusl.cz/ntk/nusl-408650.

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The thesis addresses response consistency in questionaries, the concept of integrity and use of integrity tests. Next chapter deals with consistency and describes possible sources of response variability and scales which is used for consistency measurement. The third chapter addresses response distortion and methods of its measurement. Last part describes cognitive functions which could affect answering a questionary and introduces a relation between psychopathological symptoms and questionary responses. The empirical part of the thesis studies response consistency in each category and relation between integrity test in work environment, consistency and demographic data of respondents. Difference between a number of identical answers about social desirability and about neutral information showed statistical significance. Therefore, hypotheses about the highest consistency in neutral information was supported. The thesis also revealed that a higher score in interference relates to a higher score of consistency. Finally, two correlations were found out. First was a positive correlation between integrity and number of years respondents have worked, second was a negative correlation between interference and age. Keywords: integrity, social desirability, consistency, validity, counterproductive behaviour
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