Journal articles: 'Temporary Intrinsics'

1

Haslanger, S. "Endurance and temporary intrinsics." Analysis 49, no. 3 (June 1, 1989): 119–25. http://dx.doi.org/10.1093/analys/49.3.119.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

FIOCCO, M. ORESTE. "TEMPORARY INTRINSICS AND RELATIVIZATION." Pacific Philosophical Quarterly 91, no. 1 (March 2010): 64–77. http://dx.doi.org/10.1111/j.1468-0114.2009.01358.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Wasserman, R. "The Argument from Temporary Intrinsics." Australasian Journal of Philosophy 81, no. 3 (September 2003): 413–19. http://dx.doi.org/10.1080/713659708.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Alai, Mario. "Lewis, Change and Temporary Intrinsics." Axiomathes 26, no. 4 (June 23, 2016): 467–87. http://dx.doi.org/10.1007/s10516-016-9296-0.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

EDDON, M. "Three Arguments from Temporary Intrinsics." Philosophy and Phenomenological Research 81, no. 3 (November 2010): 605–19. http://dx.doi.org/10.1111/j.1933-1592.2010.00371.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Ehring, D. "Lewis, temporary intrinsics and momentary tropes." Analysis 57, no. 4 (October 1, 1997): 254–58. http://dx.doi.org/10.1093/analys/57.4.254.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Sider, T. "The Stage View and Temporary Intrinsics." Analysis 60, no. 1 (January 1, 2000): 84–88. http://dx.doi.org/10.1093/analys/60.1.84.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Craig, W. L. "McTaggart's paradox and the problem of temporary intrinsics." Analysis 58, no. 2 (April 1, 1998): 122–27. http://dx.doi.org/10.1093/analys/58.2.122.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Oaklander, L. N. "Craig on McTaggart's Paradox and the problem of temporary intrinsics." Analysis 59, no. 4 (October 1, 1999): 314–18. http://dx.doi.org/10.1093/analys/59.4.314.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Brower, J. E. "Aristotelian Endurantism: A New Solution to the Problem of Temporary Intrinsics." Mind 119, no. 476 (October 1, 2010): 883–905. http://dx.doi.org/10.1093/mind/fzq072.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

de Jong, Jeroen P., Christa L. Wilkin, and Cristina Rubino. "The association between perceived personal power, team commitment and intrinsic motivation for permanent and temporary workers." Economic and Industrial Democracy 40, no. 2 (October 31, 2018): 257–79. http://dx.doi.org/10.1177/0143831x18805848.

Full text

Abstract:

To date, research on how temporary workers are embedded in teams is limited to how they impact their co-workers with permanent contracts and how temporary workers impact team functioning and performance through power structures in teams. We know very little about how the perceptions of personal power of temporary and permanent workers affect their own motivation and commitment. This study aims to assess the relationship between perceived personal power, intrinsic motivation and team commitment for temporary versus permanent workers. Drawing on Conservation of Resources Theory, the authors propose that this association is non-linear for temporary workers and linear for permanent workers. They test these assumptions using a sample of 64 temporary and 275 permanent workers nested in 58 teams. Multilevel analyses show that for temporary workers, the association between personal power perceptions and intrinsic motivation and team commitment flattens at moderate to high levels of perceived personal power. For permanent workers, the study finds a linear relationship. Implications for theory are discussed.

APA, Harvard, Vancouver, ISO, and other styles

12

Zhong, L., L. J. Sonmor, A. H. Manson, and C. E. Meek. "The influence of time-dependent wind on gravity-wave propagation in the middle atmosphere." Annales Geophysicae 13, no. 4 (April 30, 1995): 375–94. http://dx.doi.org/10.1007/s00585-995-0375-6.

Full text

Abstract:

Abstract. Ray-tracing techniques are used to computationally investigate the propagation of gravity waves through the middle atmosphere, as characterized by the vertically varying CIRA-86 wind and temperature models, plus a tidal wind model that varies temporally as well as vertically. For the wave parameters studied here, the background wind variation has a much stronger influence on the ray path and changes in wave characteristics than does the temperature variation. The temporal variation of the tidal component of the wind changes the observed frequency, sometimes substantially, while leaving the intrinsic frequency unaltered. It also renders temporary any critical levels that occur in the tidal region. Different starting times for the rays relative to the tidal phase provide different propagation environments, so that the temporary critical levels appear at different heights. The lateral component of the tidal wind is shown to advect propagating wave packets; the maximum lateral displacement of a packet varies inversely with its vertical group velocity. Time-dependent effects are more pronounced in local winter than in summer.

APA, Harvard, Vancouver, ISO, and other styles

13

Eftekhari, Helen. "Temporary pacing: an overview." British Journal of Cardiac Nursing 16, no. 9 (September 2, 2021): 1–8. http://dx.doi.org/10.12968/bjca.2021.0080.

Full text

Abstract:

This article will review pacing in the context of acute care, with a focus on temporary pacing. Beginning with an overview of the heart's intrinsic electrical conduction system and its function, the discussion moves on to pacing, acute clinical presentations and indications for pacing. This includes an overview of temporary pacing, with the different approaches being percussion, transcutaneous, transvenous and epicardial. There are specific cardiac patient groups at high risk of developing bradyarrhythmias and, in the absence of other measures, potentially requiring emergency pacing. These groups include patients who have experienced a myocardial infarction following cardiac surgery and post transcatheter aortic valve implant. Nurses providing care for patients with temporary transvenous wires need an understanding of the potential complications and to recognise indications for moving on to a permanent pacing system.

APA, Harvard, Vancouver, ISO, and other styles

14

Chen, Pei-Chen, Ming-Chao Wang, and Shih-Chieh Fang. "Does motivation matter? The influence of the agency perspective on temporary agency workers." Employee Relations 39, no. 4 (June 5, 2017): 561–81. http://dx.doi.org/10.1108/er-06-2016-0124.

Full text

Abstract:

Purpose Based on agency perspective on temporary agency workers, the purpose of this paper is to explore the relationship between firms’ agency problems and agency cost on agency workers; moreover, intrinsic motivation and extrinsic motivation are considered in seeking to understand how they moderate this relationship. Design/methodology/approach Using the Hsinchu Science Park directory of corporate affiliations as a sample frame, the authors adopted a paired questionnaire which included two parts in order to consider the possible problem of common method variances. The first part is completed by the manager of the firms and the second part is completed by his/her temporary agency workers. Finally, 94 firms completed questionnaires, providing a total sample of 94 R&D managers and 458 temporary agency workers. The rate of participation was 31.65 percent. Findings Using a questionnaire survey of 94 high-tech firms, from which a total of 94 R&D managers and 458 temporary agency workers participated, the results show that firms’ agency problems have a positive influence on the agency cost of monitoring temporary agency workers. In addition, while this relationship is negatively moderated by extrinsic motivation, intrinsic motivation has a non-significant moderating effect. Originality/value The managers of firms should consider not only the short-term flexibility of employing temporary agency workers, but also the long-term cultivation of promoting great agency workers. This could maximize the efficiency of the interaction between intrinsic motivation and extrinsic motivation. Of course, the firms should think about how to reduce the agency problems created by goal conflict, information asymmetry and risk sharing with temporary agency workers, because this could also provide a chance for the firms to decrease agency costs spent on monitoring.

APA, Harvard, Vancouver, ISO, and other styles

15

Sobral, Filipa, Maria José Chambel, and Filipa Castanheira. "The Temporary Agency Worker’s Motivation Profile Analysis." International Journal of Environmental Research and Public Health 18, no. 13 (June 24, 2021): 6779. http://dx.doi.org/10.3390/ijerph18136779.

Full text

Abstract:

The Self-Determination Theory (SDT) establishes that human motivations can take different forms (e.g., amotivation, extrinsic and intrinsic motivation), yet it is only recently that the theory has been advanced to explain how these different forms combine to influence temporary agency workers’ (TAWs) affective commitment and their perception over the human resources practices (HRP) applied. We tested this theory with data from seven temporary agency companies (N = 3766). Through latent profile analysis (LPA) we identified five distinct motivation profiles and found that they differed in their affective commitment to the agency and to the client-company, and in their perception of HRP. We verified that temporary agency workers in more intrinsic profiles had more positive outcomes and a better perception of the investment made by the companies, than did TAWs in more extrinsic profiles. Additionally, when TAWs were able to integrate the reasons for being in this work arrangement, the negative effect of the extrinsic motivation was attenuated, and it was possible to find moderated profiles in which TAWs also showed more positive results than TAWs with only extrinsic motives. These differences are consistent with the notion that a motivation profile provides a context that determines how the individual components are experienced. Theoretical and practical implications of this context effect are discussed.

APA, Harvard, Vancouver, ISO, and other styles

16

Micallef, Charles. "Can Rust Spread Through Temporary Contact?" Innovations in Corrosion and Materials Science (Formerly Recent Patents on Corrosion Science) 9, no. 1 (September 24, 2019): 60–65. http://dx.doi.org/10.2174/2352094909666190228120012.

Full text

Abstract:

Background: Despite the process of rusting being well known, it was uncertain whether rust was contagious or not through temporary contact that is, involving no permanent bonding. Objective: The study investigated whether rust could be transmitted through temporary contact using controls. Methods: Eight rusted steel wool rolls, each less than 3.50 g were staggeringly arranged in groups of four onto two non-rusted steel plates, each measuring 400 x 200 mm, with control cells in between. After 10 days, rust stains formed on the plates and the rolls were removed. The conspicuous stains were monitored every month by means of manual tracing. After six monthly observations, the first month tracings were superimposed onto each respective plate. Results: Although intrinsic rust had formed on the control and experimental cells, the original stains remained constant in shape and size. Conclusion: Rust is probably not transmitted to other metals by simple contact

APA, Harvard, Vancouver, ISO, and other styles

17

Park, Ju Seong, So Hui Yun, and Jong Cook Park. "Intrinsic positive end-expiratory pressure caused by temporary partial upper airway obstruction in a patient with bronchiectasis." Journal of Medicine and Life Science 12, no. 1 (June 1, 2015): 1–3. http://dx.doi.org/10.22730/jmls.2015.12.1.1.

Full text

Abstract:

We report the case of a 71-year-old female patient with bronchiectasis who developed temporary partial upper airwayobstruction and intrinsic positive end-expiratory pressure (PEEP) caused by the movement of accumulated secretions from thelower respiratory tract to the upper respiratory tract because of a change in position. Changes in respiratory dynamics and themodification of extrinsic PEEP need to be considered in such patients with intrinsic PEEP.

APA, Harvard, Vancouver, ISO, and other styles

18

Hofmann, Frank. "TEMPORALLY LOCALISED FACTS AND THE PROBLEM OF INTRINSIC CHANGE." Ratio 18, no. 1 (March 2005): 39–47. http://dx.doi.org/10.1111/j.1467-9329.2005.00269.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Babadi, Baktash, and L. F. Abbott. "Intrinsic Stability of Temporally Shifted Spike-Timing Dependent Plasticity." PLoS Computational Biology 6, no. 11 (November 4, 2010): e1000961. http://dx.doi.org/10.1371/journal.pcbi.1000961.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Solinger, Dorothy J. "“Temporary Residence Certificate” Regulations in Wuhan, May 1983." China Quarterly 101 (March 1985): 98–103. http://dx.doi.org/10.1017/s0305741000015836.

Full text

Abstract:

In mid May 1983 the Wuhan Public Security Bureau posted a notice along the walls of Hankow on “temporary residence certificates” for non-native personnel coming into the city to work. Since a check of the State Council Bulletin and the People's Daily for the months surrounding this time (from 1 January through 31 July 1983) turned up no similar central-level document, one must conclude that the source for this circular was local. Also, in the period since (through the time of final preparation of the present manuscript, late March 1984), those sources have still not published any authoritative rulings on this matter, insofar as I have been able to verify. Moreover, recent press accounts pertaining to city household registration describe decisions about this work as if they were taken by the municipalities themselves. Thus, the regulations translated and analysed below may only represent the situation and its handling in one particular region. Nonetheless, their intrinsic interest, their broader implications and their import reach far beyond this one case.

APA, Harvard, Vancouver, ISO, and other styles

21

Shipp, Thomas, Krzysztof Izdebski, Charles Reed, and Philip Morrissey. "Intrinsic Laryngeal Muscle Activity in a Spastic Dysphonia Patient." Journal of Speech and Hearing Disorders 50, no. 1 (February 1985): 54–59. http://dx.doi.org/10.1044/jshd.5001.54.

Full text

Abstract:

EMG activity from four intrinsic laryngeal muscles (thyroarytenoid, posterior cricoarytenoid, interarytenoid, and cricothyroid) was obtained from one female spastic dysphonia patient while she performed a variety of speech and nonspeech tasks. These tasks were performed before and during a period of temporary unilateral laryngeal muscle paralysis. In the nonparalyzed condition, adductory muscle activity showed intermittent sudden increases that coincided with momentary voice arrests. These muscle patterns and accompanying voice interruptions were not present either when speech was produced in falsetto register or at anytime during the paralysis condition. The data suggest that individuals with this type of spastic dysphonia have normal morphology of recurrent laryngeal nerves and intrinsic laryngeal muscles, which means that the triggering mechanism(s) for spastic dysphonia symptoms must be located at some point neurologically upstream from the larynx.

APA, Harvard, Vancouver, ISO, and other styles

22

Bartoll, Xavier, and Raul Ramos. "Quality of work, economic crisis, and temporary employment." International Journal of Manpower 41, no. 1 (October 29, 2019): 37–51. http://dx.doi.org/10.1108/ijm-06-2018-0177.

Full text

Abstract:

Purpose The purpose of this paper is to analyse the association between the type of contract (temporary vs permanent) and the quality of work and its different dimensions before and after the economic crisis among Spanish employees. Design/methodology/approach Structural equations techniques are used to analyse the association between the type of contract and the work quality and its different dimensions before and after the crisis. Data are drawn from the 2006/2007 and 2009/2010 waves of the Encuesta de Calidad de Vida en el Trabajo. Findings The results show that in the two considered periods there are no differences in quality of work among male involuntary temporary workers and those with permanent contracts. However, there is an adverse widening gap across all dimensions of work quality for women in involuntary temporary employment during the economic crisis. There is also a shift among men and women in involuntary temporary employment from valuing intrinsic job quality dimension in the pre-crisis period to valuing more the work environment dimension during the crisis period. Research limitations/implications The analysis is limited by the continuity of variables across years and the high proportion of missing values in some variables. The obtained results cannot be interpreted in terms of causality. Originality/value This is the first study to consider whether the deterioration in the Spanish labour market during the crisis has affected the relationship between the type of contract and the different dimensions of the quality of work.

APA, Harvard, Vancouver, ISO, and other styles

23

Dai, Lingling, Qiang Xu, Xing Xiong, Yang Yu, Ximing Wang, Hui Dai, Hongru Zhao, and Jun Ke. "Propagation Structure of Intrinsic Brain Activity in Migraine without Aura." Brain Sciences 12, no. 7 (July 10, 2022): 903. http://dx.doi.org/10.3390/brainsci12070903.

Full text

Abstract:

Previous studies have revealed highly reproducible patterns of temporally lagged brain activity in healthy human adults. However, it is unknown whether temporal organization of intrinsic activity is altered in migraines or if it relates to migraine chronification. In this resting-state functional magnetic resonance imaging study, temporal features of intrinsic activity were investigated using resting-state lag analysis, and 39 episodic migraine patients, 17 chronic migraine patients, and 35 healthy controls were assessed. Temporally earlier intrinsic activity in the hippocampal complex was revealed in the chronic migraine group relative to the other two groups. We also found earlier intrinsic activity in the medial prefrontal cortex in chronic compared with episodic migraines. Both migraine groups showed earlier intrinsic activity in the lateral temporal cortex and sensorimotor cortex compared with the healthy control group. Across all patients, headache frequency negatively correlated with temporal lag of the medial prefrontal cortex and hippocampal complex. Disrupted propagation of intrinsic activity in regions involved in sensory, cognitive and affective processing of pain may contribute to abnormal brain function during migraines. Decreased time latency in the lateral temporal cortex and sensorimotor cortex may be common manifestations in episodic and chronic migraines. The temporal features of the medial prefrontal cortex and hippocampal complex were associated with migraine chronification.

APA, Harvard, Vancouver, ISO, and other styles

24

Dwivedula, Ravikiran, Christophe Bredillet, and Ralf Müller. "Work motivation as a determinant of organisational and professional commitment in temporary organisations: theoretical lenses and propositions." Journal of Project, Program & Portfolio Management 4, no. 1 (October 20, 2013): 11. http://dx.doi.org/10.5130/pppm.v4i1.2610.

Full text

Abstract:

The purpose of this paper is to present a theoretical framework to investigate the relationship between work motivation, organisational commitment and professional commitment in temporary organisations. Through a review of theory, we contend that work motivation has two major patterns — internal motivation (which includes intrinsic, need-based and self-deterministic theories), and external motivation (which includes cognitive or process-based theories of motivation) through which it has been investigated. We also hold the nature of employee commitment to be of three types — affective, continuance and normative. This commitment may be towards either the organisation or the profession. A literature review revealed that the characteristics of the temporary organisation — specifically tenure and task — regulate the relationship between work motivation, organisational commitment and professional commitment. Testable propositions are presented

APA, Harvard, Vancouver, ISO, and other styles

25

Ishida, Joji, Saira Alli, Andrew Bondoc, Brian Golbourn, Nesrin Sabha, Kristina Mikloska, Dilakshan Srikanthan, et al. "DDEL-01. ENHANCING DRUG DELIVERY WITH MRgFUS FOR DIFFUSE INTRINSIC PONTINE GLIOMA MODEL." Neuro-Oncology 22, Supplement_3 (December 1, 2020): iii283. http://dx.doi.org/10.1093/neuonc/noaa222.036.

Full text

Abstract:

Abstract Diffuse intrinsic pontine glioma (DIPG) is a surgically unresectable and devasting tumor in children. To date, there have been no effective chemotherapeutics despite a myriad of clinical trials. The intact blood-brain barrier (BBB) in part is responsible for the limited clinical response to chemotherapy. MRI guided focused ultrasound (MRgFUS) is a promising non-invasive tissue ablative method for CNS tumors. Moreover, MRgFUS allows for the temporary disruption of BBB. Our first objective was to determine the feasibility and safety of temporary BBB disruption within the brainstem using MRgFUS following intravenous (IV) administration of microbubbles in vivo. Our second objective was to select effective chemotherapeutics against DIPG cell lines, and to examine their therapeutic effects with MRgFUS in a mouse model of DIPG which exhibits an intact BBB. The non-invasive opening of the BBB was determined in the brainstem of normal rodents using physiological monitoring and histological analysis. Doxorubicin was selected from a drug screen consisting of conventional chemotherapeutics using SU-DIPG4 and SU-DIPG17 cell lines. We established SU-DIPG17 xenografts which demonstrated diffusely infiltrative tumor growth similar to human DIPG. By LC-MS/MS analysis, MRgFUS led to a 4-fold increase in doxorubicin concentrations within the brainstem tumors following IV administration when compared to IV administration alone, We demonstrated feasibility and safety of MRgFUS in the rodent brainstem and have shown that MRgFUS increases doxorubicin uptake in the brainstem of a rodent model of DIPG. These preclinical data will be helpful in designing clinical trials of BBB disruption using MRgFUS for DIPG in children.

APA, Harvard, Vancouver, ISO, and other styles

26

Cannestra, Andrew F., Nader Pouratian, Marc H. Shomer, and Arthur W. Toga. "Refractory Periods Observed by Intrinsic Signal and Fluorescent Dye Imaging." Journal of Neurophysiology 80, no. 3 (September 1, 1998): 1522–32. http://dx.doi.org/10.1152/jn.1998.80.3.1522.

Full text

Abstract:

Cannestra, Andrew F., Nader Pouratian, Marc H. Shomer, and Arthur W. Toga. Refractory periods observed by intrinsic signal and fluorescent dye imaging. J. Neurophysiol. 80: 1522–1532, 1998. All perfusion-based imaging modalities depend on the relationship between neuronal and vascular activity. However, the relationship between stimulus and response was never fully characterized. With the use of optical imaging (intrinsic signals and intravascular fluorescent dyes) during repetitive stimulation paradigms, we observed reduced responses with temporally close stimuli. Cortical evoked potentials, however, did not produce the same reduced responsiveness. We therefore termed these intervals of reduced responsiveness “refractory periods.” During these refractory periods an ability to respond was retained, but at a near 60% reduction in the initial magnitude. Although increasing the initial stimulus duration lengthened the observed refractory periods, significantly novel or temporally spaced stimuli overcame them. We observed this phenomenon in both rodent and human subjects in somatosensory and auditory cortices. These results have significant implications for understanding the capacities, mechanisms, and distributions of neurovascular coupling and thereby possess relevance to all perfusion-dependent functional imaging techniques.

APA, Harvard, Vancouver, ISO, and other styles

27

Hoppe, David, Stefan Helfmann, and Constantin A. Rothkopf. "Humans quickly learn to blink strategically in response to environmental task demands." Proceedings of the National Academy of Sciences 115, no. 9 (February 14, 2018): 2246–51. http://dx.doi.org/10.1073/pnas.1714220115.

Full text

Abstract:

Eye blinking is one of the most frequent human actions. The control of blinking is thought to reflect complex interactions between maintaining clear and healthy vision and influences tied to central dopaminergic functions including cognitive states, psychological factors, and medical conditions. The most imminent consequence of blinking is a temporary loss of vision. Minimizing this loss of information is a prominent explanation for changes in blink rates and temporarily suppressed blinks, but quantifying this loss is difficult, as environmental regularities are usually complex and unknown. Here we used a controlled detection experiment with parametrically generated event statistics to investigate human blinking control. Subjects were able to learn environmental regularities and adapted their blinking behavior strategically to better detect future events. Crucially, our design enabled us to develop a computational model that allows quantifying the consequence of blinking in terms of task performance. The model formalizes ideas from active perception by describing blinking in terms of optimal control in trading off intrinsic costs for blink suppression with task-related costs for missing an event under perceptual uncertainty. Remarkably, this model not only is sufficient to reproduce key characteristics of the observed blinking behavior such as blink suppression and blink compensation but also predicts without further assumptions the well-known and diverse distributions of time intervals between blinks, for which an explanation has long been elusive.

APA, Harvard, Vancouver, ISO, and other styles

28

Oswald, Hanno, Gunnar Klein, Thorben Koenig, Ulrich Luesebrink, David Duncker, and Ajmal Gardiwal. "Cryoballoon pulmonary vein isolation temporarily modulates the intrinsic cardiac autonomic nervous system." Journal of Interventional Cardiac Electrophysiology 29, no. 1 (June 16, 2010): 57–62. http://dx.doi.org/10.1007/s10840-010-9491-7.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Sharma, Akhil Kumar, Nirdesh Jain, Safal Safal, Vikas Kumar, and Sudhanshu Kumar Dwivedi. "Recurrent Postmyocardial Infarction Ventricular Tachycardia: An Unusual Culprit." Case Reports in Cardiology 2015 (2015): 1–3. http://dx.doi.org/10.1155/2015/564394.

Full text

Abstract:

Although temporary transvenous pacing is life-saving in patients with myocardial infarction who develop bradyarrhythmias, the electrical complications resulting from it can be fatal and are rarely reported. We report here a patient with acute inferior wall myocardial infarction who required temporary transvenous pacing due to second-degree atrioventricular block accompanied with hypotension. Following coronary angiography and successful revascularisation, the patient developed multiple episodes of monomorphic and polymorphic ventricular tachycardia as well as ventricular fibrillation which on careful inspection were found to be initiated by fusion of the intrinsic and paced complexes. The problem of malignant ventricular tachycardia was solved by simple removal of the pacing lead. To the best of our knowledge, malignant ventricular tachycardia of both monomorphic and polymorphic types initiated by fusion complexes in a paced patient has not been reported in literature.

APA, Harvard, Vancouver, ISO, and other styles

30

Davidović-Rakić, Jelena, and Igor Đurić. "Possibilities of developing motivation for learning among students of the University of Priština with temporary headquarters in Kosovska Mitrovica." Bastina, no. 55 (2021): 279–96. http://dx.doi.org/10.5937/bastina31-34164.

Full text

Abstract:

The paper strives to consider the intensity and structure of motivation for studying among undergraduates of the University of Priština in Kosovska Mitrovica, as well as to check whether there are differences in the intensity of intrinsic and extrinsic motivation among undergraduates of different faculties. In addition, drawing on the Theory of Self-Determination of Edward Deci and Richard Ryan, we were interested in the structure of motivation for studying in two sociocultural areas: Serbia and Croatia. The research was conducted during the summer semester of 2017 on the premises of five faculties. The Thomas-Miller scale was used to examine motivation for studying. The most intense individual motivator for studying is "I am studying, because I will be able to get / find a better job", and the presence of the intrinsic factor of motivation for studying is more pronounced. The research findings have indicated that all motivators are classified into two factors, intrinsic and extrinsic ones, and account for 51.40% of the variance of the observed measurement space. Our research obtained a different structure of factors, in relation to the research results in Croatia. Motivators "... because I simply have to" and "… because I will be able to get / find a better job" have replaced affiliation, in relation to the structure of factors obtained in the Croatian sample of respondents. Both observed factors of motivation for studying are the most intense among undergraduates of the Faculty of Medicine. Undergraduates from other faculties do not differ statistically significantly in the intensity of both motivational factors.

APA, Harvard, Vancouver, ISO, and other styles

31

Sobral, Filipa, Maria José Chambel, and Filipa Castanheira. "Managing motivation in the contact center: The employment relationship of outsourcing and temporary agency workers." Economic and Industrial Democracy 40, no. 2 (June 6, 2016): 357–81. http://dx.doi.org/10.1177/0143831x16648386.

Full text

Abstract:

Grounded in self-determination theory (SDT), this research builds a motivation profile typology of contingent workers in the contact center industry, compares outsourcer (OW) and temporary agency workers’ (TAW) profiles, and differentiates their human resources practices (HRP) perceptions and affective commitment. The hypotheses were tested in a sample of 2078 Portuguese contingent workers, through several statistical procedures, including latent profile analysis. Six profiles were identified. As expected, OW were mostly in the more intrinsic profiles, whereas TAW were in the more extrinsic ones. However, the contingent employment format did not moderate the relationship between motivation, HRP perceptions, and affective commitment.

APA, Harvard, Vancouver, ISO, and other styles

32

Ishida, Joji, Saira Alli, Andrew Bondoc, Naohide Fujita, Hynynen Kullervo, and Rutka James. "ET-04 Enhancing drug delivery with MRI-guided focused ultrasound for diffuse intrinsic pontine glioma model." Neuro-Oncology Advances 2, Supplement_3 (November 1, 2020): ii6. http://dx.doi.org/10.1093/noajnl/vdaa143.024.

Full text

Abstract:

Abstract Diffuse intrinsic pontine glioma (DIPG) is surgically unresectable and one of the most devasting tumours in children. To date, there have been no effective chemotherapeutics against DIPG, despite a myriad of clinical trials. The intact blood-brain barrier (BBB) is partly responsible for the limited clinical response to chemotherapy. MRI-guided focused ultrasound (MRgFUS) is a promising non-invasive tissue ablation method for treating CNS tumours. Moreover, MRgFUS allows for temporary and repeatable BBB disruption. Our first objective was to determine the feasibility and safety of temporary BBB disruption within the brainstem using MRgFUS following intravenous administration of microbubbles in vivo. Our second objective was to select effective chemotherapeutics against DIPG cell lines, and to examine their therapeutic effects with MRgFUS in a murine model of DIPG which exhibits an intact BBB. Non-invasive opening of the BBB was determined in the brainstem of normal rodents using physiological monitoring and histological analysis. Doxorubicin was selected from a drug screen consisting of conventional chemotherapeutics tested against DIPG cell lines. We established SU-DIPG17 orthotopic xenografts which demonstrated diffusely infiltrative tumour growth. By LC-MS/MS analysis, MRgFUS led to a 4-fold increase in doxorubicin concentrations within the brainstem tumours as compared to controls. Moreover, the volumetric tumour growth rate was significantly suppressed in MRgFUS-treated animals, which also exhibited decreased Ki-67 expression. We demonstrated the feasibility and safety of MRgFUS in the rodent brainstem and have shown that MRgFUS increases doxorubicin uptake in the brainstem of a rodent model of DIPG. This preclinical data provides critical support for clinical trials investigating MRgFUS-mediated BBB opening, which may greatly improve chemotherapeutic efficacy against DIPG in children.

APA, Harvard, Vancouver, ISO, and other styles

33

Takayasu, Masakazu, and Ralph G. Dacey. "Spontaneous tone of cerebral parenchymal arterioles: a role in cerebral hyperemic phenomena." Journal of Neurosurgery 71, no. 5 (November 1989): 711–17. http://dx.doi.org/10.3171/jns.1989.71.5.0711.

Full text

Abstract:

✓ An isolated cerebral arteriole preparation was used to test the hypothesis that a temporary reduction in transmural pressure causes a subsequent vasodilation mediated by mechanisms intrinsic to the vessel wall. Thirty-five cerebral vessels of 44.7 ± 1.4 µm (± standard error of the mean) mean diameter were cannulated in vitro and pressurized at a transmural pressure of 60 mm Hg; after an equilibration period the vessels developed spontaneous tone. When transmural pressure was decreased to 0 mm Hg for a period of 4 minutes then returned to 60 mm Hg, vessels dilated to 155.1% ± 6.8% of control diameter before gradually redeveloping spontaneous tone in 5.5 ± 0.7 minutes. Varying the duration of the period during which transmural pressure was at 0 mm Hg had no significant effect on the degree of vasodilation. Conversely, varying the level of decreased transmural pressure between 0 and 20 mm Hg significantly affected both the magnitude of vasodilation and the time course of spontaneous tone recovery. These findings indicate that a temporary period of decreased transmural pressure may result in a loss of spontaneous tone in the resistance vessels of the cerebral microcirculation. Mechanisms intrinsic to the vessel wall may play a significant role in the early stage of post-reperfusion hyperemia. Such mechanisms could also be implicated in other hyperemic phenomena affecting the cerebral circulation, such as the rapid increase in intracranial pressure after subarachnoid hemorrhage, the development of the normal perfusion pressure breakthrough phenomenon, and the initiation of intracranial pressure plateau waves.

APA, Harvard, Vancouver, ISO, and other styles

34

Brandl, Elisabeth, Karine Abadie, Markus Wimplinger, Juergen Burggraf, Thomas Uhrmann, Julian Bravin, Frank Fournel, and Pierre Montmeat. "Critical Process Parameters And Failure Analysis For Temporary Bonded Wafer Stacks." Additional Conferences (Device Packaging, HiTEC, HiTEN, and CICMT) 2016, DPC (January 1, 2016): 001255–76. http://dx.doi.org/10.4071/2016dpc-wp14.

Full text

Abstract:

Temporary bonding is a ley process for almost any 3D integration scheme. It offers not only more stability during the thinning process but also allows handling for backside processing of thin wafers like interposers during subsequent process steps [1–2]. Although the temporary bonding technology is already used in high volume manufacturing and has proven high yield process, nevertheless, some limitation appears for some specific applications [3-4-5]. One critical failure origin is delamination, which can lead to wafer breakage and therefore yield loss. This separation of the device wafer and the carrier wafer typically occurs when the temporary bonded wafer stack (device wafer, carrier wafer and temporary bonding adhesive in between) experiences further processing done under high temperature and low vacuum like PECVD deposition. Further insight into processing parameters and a better understanding of the key contributing factors as well as its dependencies help to prevent this failure. To investigate the root cause of the delamination, thermoplastic materials, which are widely used for temporary bonding and debonding applications have been used as temporary bonding adhesives in this work. Different process parameters were investigated individually but also in combination to find the origin of the delamination. These parameters include post thinning annealing temperature, which was varied up to 370C, vacuum level, thermal gradient, bow and warp and intrinsic stress of the thin device wafer. After evaluation of the main parameters affecting the delamination appearance, two extreme cases were experimented in order to check the hypothesis. The first one exhibits delaminations even using a very soft processing conditions for a temporary bonding integration and the second case is able to withstand extreme processing conditions like high temperature up to 370C under vacuum of about 1mbar without delamination appearance. In addition, during this work, the mechanical coupling existing between the carrier and the device wafer thanks to the adhesive has been investigated. Here, a thermoplastic material was used in a temporary bonded structures using wafers with different coefficients of thermal expansion (CTE). During thermal treatment, this CTE difference induce important internal stress bow of the wafer stack. The temperature dependence of the mechanical coupling is monitored during the annealing. A mechanical decoupling between the two wafers occurs when above the polymer glass transition temperature. As a result, the rheology of the thermoplastic layer is found as a contributor to the delamination mechanism. Critical combinations of process parameters in temporary bonding process are then clearly identified and will be presented in this work.

APA, Harvard, Vancouver, ISO, and other styles

35

Tsigilis, Nikolaos, and Argiris Theodosiou. "Temporal Stability of the Intrinsic Motivation Inventory." Perceptual and Motor Skills 97, no. 1 (August 2003): 271–80. http://dx.doi.org/10.2466/pms.2003.97.1.271.

Full text

Abstract:

To examine the temporal stability of the Intrinsic Motivation Inventory a Greek version was administered to 144 undergraduate students after an endurance field test. The same procedure was repeated one week later. Factor analysis followed by varimax rotation showed that three factors (Perceived Competence, Interest/enjoyment, and Effort/importance) explained 65.26% of the total variance. Computed intraclass correlation coefficients (ICC) were .61 for the Perceived Competence subscale, .86 for the Interest/enjoyment, .60 for the Effort/importance, and .70 for the overall scale. The results, however, were modified when the sample was divided in two groups. The first represented small changes in perceived competence between the first and the second measurement, while the second one represented large changes between the two measurements. Recalculated intraclass correlation coefficients for individuals whose Perceived Competence score remained relatively stable yield a high value (.92), whereas individuals whose Perceived Competence changed yield an extremely low value (.60). It was concluded that the Intrinsic Motivation Inventory provides a temporally stable measure, given that perceived competence has not been markedly changed.

APA, Harvard, Vancouver, ISO, and other styles

36

Blood, Anne J., Nader Pouratian, and Arthur W. Toga. "Temporally Staggered Forelimb Stimulation Modulates Barrel Cortex Optical Intrinsic Signal Responses to Whisker Stimulation." Journal of Neurophysiology 88, no. 1 (July 1, 2002): 422–37. http://dx.doi.org/10.1152/jn.2002.88.1.422.

Full text

Abstract:

Characterization of neurovascular relationships is critical to accurate interpretation of functional neuroimaging data. We have previously observed spatial uncoupling of optical intrinsic signal imaging (OIS) and evoked potential (EP) responses in rodent barrel cortex following simultaneous whisker and forelimb stimulation, leading to changes in OIS response magnitude. To further test the hypothesis that this uncoupling may have resulted from “passive” overspill of perfusion-related responses between functional regions, we conducted the present study using temporally staggered rather than simultaneous whisker and forelimb stimulation. This paradigm minimized overlap of neural responses in barrel cortex and forelimb primary somatosensory cortex (SI), while maintaining overlap of vascular response time courses between regions. When contrasted with responses to 1.5-s lone-whisker stimulation, staggered whisker and forelimb stimulation resulted in broadening of barrel cortex OIS response time course in the temporal direction of forelimb stimulation. OIS response peaks were also temporally shifted toward the forelimb stimulation period; time-to-peak was shorter (relative to whisker stimulus onset) when forelimb stimulation preceded whisker stimulation and longer when forelimb stimulation followed whisker stimulation. In contrast with OIS and EP magnitude decreases previously observed during simultaneous whisker/forelimb stimulation, barrel cortex OIS response magnitude increased during staggered stimulation and no detectable changes in underlying EP activity were observed. Spatial extent of barrel cortex OIS responses also increased during staggered stimulation. These findings provide further evidence for spatial uncoupling of OIS and EP responses, and emphasize the importance of temporal stimulus properties on the effects of this uncoupling. It is hypothesized that spatial uncoupling is a result of passive overspill of perfusion-related responses into regions distinct from those which are functionally active. It will be important to consider potential influences of this uncoupling when designing and interpreting functional imaging studies that use hemodynamic responses to infer underlying neural activity.

APA, Harvard, Vancouver, ISO, and other styles

37

Cacciotti, Chantel, Kevin Liu, Daphne Haas-Kogan, and Katherine Warren. "DIPG-01. REIRRADIATION PRACTICES FOR DIFFUSE INTRINSIC PONTINE GLIOMA." Neuro-Oncology 22, Supplement_3 (December 1, 2020): iii287. http://dx.doi.org/10.1093/neuonc/noaa222.053.

Full text

Abstract:

Abstract INTRODUCTION Diffuse intrinsic pontine gliomas (DIPG) are a leading cause of brain tumor deaths in children. Current standard of care includes focal radiation therapy (RT). Despite clinical improvement in the majority of patients, the effect is temporary and median survival is less than one year. The use of reirradiation and possible benefit has been reported in progressive DIPG, yet standardized approaches are lacking. We conducted an internet-based survey to assess physicians’ practices in pediatric DIPG. METHODS A 14-question REDCap survey regarding re-irradiation practices was emailed to 396 physicians identified through an International Pediatric Neuro-Oncology and Radiation-Oncology database. RESULTS Response rate was 35% overall (radiation-oncologists, 28%; pediatric oncologists, 57%). Two participants were excluded (did not treat DIPG). Participants included radiation-oncologists (62%), pediatric oncologists (7%), and pediatric neuro-oncologists (29%). Most physicians (62%) treated 1–5 DIPG patients per year, with 10% treating >10/year. Reirradiation was considered a treatment option in 88%. Progressive disease or worsening clinical status were the most common reasons to consider reirradiation. The majority (84%) considered reirradiation a minimum of 6 months following initial RT. Doses varied, with median total dose 24Gy (range 12–60); 2Gy/fraction (range 1–9). Concurrent use of systemic agents with reirradiation was considered in 46%, mainly with targeted agents (37%), biologics (34%), or immunotherapy (25%). One-time reirradiation was the most common practice (71%). Interestingly, 9% of respondents would not consider reirradiation. CONCLUSION Although, the vast majority of physicians agree with re-irradiation as a treatment option for DIPG the total doses varied, and further clinical trials are needed.

APA, Harvard, Vancouver, ISO, and other styles

38

Kimura, Yuki, Masataka Sumiyoshi, Kenji Inoue, Masayuki Shiozaki, Kentaro Fukuda, Yasumasa Fujiwara, Haruna Tabuchi, et al. "Stability of intrinsic rhythm in pacemaker‐dependent patients during pacemaker replacement: Can we predict the need for temporary pacing?" Journal of Arrhythmia 34, no. 4 (May 28, 2018): 450–54. http://dx.doi.org/10.1002/joa3.12072.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Taillefumier, Thibaud, Jonathan Touboul, and Marcelo Magnasco. "Exact Event-Driven Implementation for Recurrent Networks of Stochastic Perfect Integrate-and-Fire Neurons." Neural Computation 24, no. 12 (December 2012): 3145–80. http://dx.doi.org/10.1162/neco_a_00346.

Full text

Abstract:

In vivo cortical recording reveals that indirectly driven neural assemblies can produce reliable and temporally precise spiking patterns in response to stereotyped stimulation. This suggests that despite being fundamentally noisy, the collective activity of neurons conveys information through temporal coding. Stochastic integrate-and-fire models delineate a natural theoretical framework to study the interplay of intrinsic neural noise and spike timing precision. However, there are inherent difficulties in simulating their networks’ dynamics in silico with standard numerical discretization schemes. Indeed, the well-posedness of the evolution of such networks requires temporally ordering every neuronal interaction, whereas the order of interactions is highly sensitive to the random variability of spiking times. Here, we answer these issues for perfect stochastic integrate-and-fire neurons by designing an exact event-driven algorithm for the simulation of recurrent networks, with delayed Dirac-like interactions. In addition to being exact from the mathematical standpoint, our proposed method is highly efficient numerically. We envision that our algorithm is especially indicated for studying the emergence of polychronized motifs in networks evolving under spike-timing-dependent plasticity with intrinsic noise.

APA, Harvard, Vancouver, ISO, and other styles

40

Chen, Kai, Jianwei Dai, and Xiaobo Zhang. "Improvement of corrosion resistance of magnesium alloys for biomedical applications." Corrosion Reviews 33, no. 3-4 (July 1, 2015): 101–17. http://dx.doi.org/10.1515/corrrev-2015-0007.

Full text

Abstract:

AbstractIn recent years, magnesium (Mg) alloys have attracted great attention due to superior biocompatibility, biodegradability, and other characteristics important for use in biodegradable implants. However, the development of Mg alloys for clinical application continues to be hindered by high corrosion rates and localized corrosion modes, both of which are detrimental to the mechanical integrity of a load-bearing temporary implant. To overcome these challenges, technologies have been developed to improve the corrosion resistance of Mg alloys, among which surface treatment is the most common way to enhance not only the corrosion resistance, but also the bioactivity of biodegradable Mg alloys. Nevertheless, surface treatments are unable to fundamentally solve the problems of fast corrosion rate and localized corrosion. Therefore, it is of great importance to alter and improve the intrinsic corrosion behavior of Mg alloys for biomedical applications. To show the significance of the intrinsic corrosion resistance of biodegradable Mg alloys and attract much attention on this issue, this article presents a review of the improvements made to enhance intrinsic corrosion resistance of Mg alloys in recent years through the design and preparation of the Mg alloys, including purifying, alloying, grain refinement, and heat treatment techniques. The influence of long-period stacking-ordered structure on corrosion behavior of the biodegradable Mg alloys is also discussed.

APA, Harvard, Vancouver, ISO, and other styles

41

De, Arpan, Dilshan H. Beligala, Vishal P. Sharma, Christian A. Burgos, Angelia M. Lee, and Michael E. Geusz. "Cancer stem cell generation during epithelial-mesenchymal transition is temporally gated by intrinsic circadian clocks." Clinical & Experimental Metastasis 37, no. 5 (August 20, 2020): 617–35. http://dx.doi.org/10.1007/s10585-020-10051-1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Kumar, Praveen, and Ramon Rabinovitch. "CEO Entrenchment and Corporate Hedging: Evidence from the Oil and Gas Industry." Journal of Financial and Quantitative Analysis 48, no. 3 (June 2013): 887–917. http://dx.doi.org/10.1017/s0022109013000276.

Full text

Abstract:

AbstractUsing a unique data set with detailed information on the derivative positions of upstream oil and gas firms during 1996–2008, we find that hedging intensity is positively related to factors that amplify chief executive officer (CEO) entrenchment and free cash flow agency costs. There is also robust evidence that hedging is motivated by the reduction of financial distress and borrowing costs, and that it is influenced by both intrinsic cash flow risk and temporary spikes in commodity price volatility. We present a comprehensive perspective on the determinants of corporate hedging, and the results are consistent with the predictions of the risk management and agency costs literatures.

APA, Harvard, Vancouver, ISO, and other styles

43

Yang, Won Ho, Peter V. Aziz, Douglas M. Heithoff, Michael J. Mahan, Jeffrey W. Smith, and Jamey D. Marth. "An intrinsic mechanism of secreted protein aging and turnover." Proceedings of the National Academy of Sciences 112, no. 44 (October 21, 2015): 13657–62. http://dx.doi.org/10.1073/pnas.1515464112.

Full text

Abstract:

The composition and functions of the secreted proteome are controlled by the life spans of different proteins. However, unlike intracellular protein fate, intrinsic factors determining secreted protein aging and turnover have not been identified and characterized. Almost all secreted proteins are posttranslationally modified with the covalent attachment of N-glycans. We have discovered an intrinsic mechanism of secreted protein aging and turnover linked to the stepwise elimination of saccharides attached to the termini of N-glycans. Endogenous glycosidases, including neuraminidase 1 (Neu1), neuraminidase 3 (Neu3), beta-galactosidase 1 (Glb1), and hexosaminidase B (HexB), possess hydrolytic activities that temporally remodel N-glycan structures, progressively exposing different saccharides with increased protein age. Subsequently, endocytic lectins with distinct binding specificities, including the Ashwell–Morell receptor, integrin αM, and macrophage mannose receptor, are engaged in N-glycan ligand recognition and the turnover of secreted proteins. Glycosidase inhibition and lectin deficiencies increased protein life spans and abundance, and the basal rate of N-glycan remodeling varied among distinct proteins, accounting for differences in their life spans. This intrinsic multifactorial mechanism of secreted protein aging and turnover contributes to health and the outcomes of disease.

APA, Harvard, Vancouver, ISO, and other styles

44

Raut, Ryan V., Anish Mitra, Scott Marek, Mario Ortega, Abraham Z. Snyder, Aaron Tanenbaum, Timothy O. Laumann, Nico U. F. Dosenbach, and Marcus E. Raichle. "Organization of Propagated Intrinsic Brain Activity in Individual Humans." Cerebral Cortex 30, no. 3 (September 13, 2019): 1716–34. http://dx.doi.org/10.1093/cercor/bhz198.

Full text

Abstract:

Abstract Spontaneous infra-slow (<0.1 Hz) fluctuations in functional magnetic resonance imaging (fMRI) signals are temporally correlated within large-scale functional brain networks, motivating their use for mapping systems-level brain organization. However, recent electrophysiological and hemodynamic evidence suggest state-dependent propagation of infra-slow fluctuations, implying a functional role for ongoing infra-slow activity. Crucially, the study of infra-slow temporal lag structure has thus far been limited to large groups, as analyzing propagation delays requires extensive data averaging to overcome sampling variability. Here, we use resting-state fMRI data from 11 extensively-sampled individuals to characterize lag structure at the individual level. In addition to stable individual-specific features, we find spatiotemporal topographies in each subject similar to the group average. Notably, we find a set of early regions that are common to all individuals, are preferentially positioned proximal to multiple functional networks, and overlap with brain regions known to respond to diverse behavioral tasks—altogether consistent with a hypothesized ability to broadly influence cortical excitability. Our findings suggest that, like correlation structure, temporal lag structure is a fundamental organizational property of resting-state infra-slow activity.

APA, Harvard, Vancouver, ISO, and other styles

45

Smyllie, Nicola J., Johanna E. Chesham, Ryan Hamnett, Elizabeth S. Maywood, and Michael H. Hastings. "Temporally chimeric mice reveal flexibility of circadian period-setting in the suprachiasmatic nucleus." Proceedings of the National Academy of Sciences 113, no. 13 (March 10, 2016): 3657–62. http://dx.doi.org/10.1073/pnas.1511351113.

Full text

Abstract:

The suprachiasmatic nucleus (SCN) is the master circadian clock controlling daily behavior in mammals. It consists of a heterogeneous network of neurons, in which cell-autonomous molecular feedback loops determine the period and amplitude of circadian oscillations of individual cells. In contrast, circuit-level properties of coherence, synchrony, and ensemble period are determined by intercellular signals and are embodied in a circadian wave of gene expression that progresses daily across the SCN. How cell-autonomous and circuit-level mechanisms interact in timekeeping is poorly understood. To explore this interaction, we used intersectional genetics to create temporally chimeric mice with SCN containing dopamine 1a receptor (Drd1a) cells with an intrinsic period of 24 h alongside non-Drd1a cells with 20-h clocks. Recording of circadian behavior in vivo alongside cellular molecular pacemaking in SCN slices in vitro demonstrated that such chimeric circuits form robust and resilient circadian clocks. It also showed that the computation of ensemble period is nonlinear. Moreover, the chimeric circuit sustained a wave of gene expression comparable to that of nonchimeric SCN, demonstrating that this circuit-level property is independent of differences in cell-intrinsic periods. The relative dominance of 24-h Drd1a and 20-h non-Drd1a neurons in setting ensemble period could be switched by exposure to resonant or nonresonant 24-h or 20-h lighting cycles. The chimeric circuit therefore reveals unanticipated principles of circuit-level operation underlying the emergent plasticity, resilience, and robustness of the SCN clock. The spontaneous and light-driven flexibility of period observed in chimeric mice provides a new perspective on the concept of SCN pacemaker cells.

APA, Harvard, Vancouver, ISO, and other styles

46

Schmitz, Erik. "Bouwlandschappen." Tijdschrift voor Historische Geografie 6, no. 1 (January 1, 2021): 61–68. http://dx.doi.org/10.5117/thg2021.1.004.schm.

Full text

Abstract:

Abstract Building landscapes A drawing by artist Jan Hoynck van Papendrecht (1858-1933) can be understood as a view of the f irst buildings along Amsterdam’s Van Eeghenstraat, as seen from his rear window. The late 19th-century method of raising polder meadows for urban expansion is also clearly visible on a hitherto mislocated drawing by Gerrit Haverkamp (1872-1926) of a building site in Amsterdam Oud-West. The chronological development of raising building sites can still be acknowledged from height differences in Amsterdams urban fabric. Building landscapes are rather underexposed in Dutch historical geography as a seemingly temporary situation. However, they are an intrinsic and sometimes longer-lasting part of the landscape’s biography and deserve more attention than they have received until now.

APA, Harvard, Vancouver, ISO, and other styles

47

Shrestha, Rohit Kumar. "Factors Influencing Employee Motivation: A Case Study of Padma Kanya Multiple Campus in Kathmandu." Tribhuvan University Journal 36, no. 01 (December 31, 2021): 146–60. http://dx.doi.org/10.3126/tuj.v36i01.43617.

Full text

Abstract:

Motivation is the set of forces that make employees willing to behave in an organization. It is a crucial function of management or human resource management. The study’s objectives are to determine employees’ motivating factors as well as to identify employees’ general attitudes towards existing motivational factors. The qualitative research method was used. Primary data were collected adopting focus group discussion, observation, and interviews. Administrative and unranked employees of Padma Kanya Multiple Campus (PKMC) were selected for study by applying the case study method. Thematic analysis of data was applied. The most important motivating factor for both temporary administrative and unranked employees (helpers in office) was job security followed by pay and overtime remuneration. Administrative employees, to great extent, need intrinsic rewards particularly recognition, responsibility, promotion, and fairness whereas unranked permanent employees also, to some extent, were influenced by intrinsic factors such as recognition, equality, fairness. A different motivating factor may apply to different levels of employees in terms of their needs and desires. The general attitude of the research participants regarding motivation seems to be poor. So, both extrinsic and extrinsic factors should be improved.

APA, Harvard, Vancouver, ISO, and other styles

48

Varella, Marco Antonio Correa. "Artistic motivations are intrinsic, specific, and temporally stable by nature: Evidence from large real-life Brazilian public data between 1987–2004." Culture and Evolution 19, no. 1 (December 19, 2022): 68–80. http://dx.doi.org/10.1556/2055.2022.00012.

Full text

Abstract:

AbstractArtistic behavior as aesthetically enhancing activities is conceptualized as a functionally autonomous activity within the evolved human behavioral repertoire. Accordingly, it should be intrinsically motivated, and it might also be expected to be temporally stable and domain specific. Preferential freely-pursued activities reflect intrinsic motivation and offer a valuable measure of artistic motivation. We used a large decades-long real-life public Brazilian data set from university applications to test these ideas. We analysed data on extra-class activities from 674.699 late-adolescents applying for university courses between 1987 and 2004, mostly between 17 and 19 years of age; approximately half men and half women. We found that 27% of individuals reported that Artistic/cultural activities were the leisure-time activity they participated in most frequently, and 32% reported they spent the longest period of free-time doing Artistic-activities (theater/cinema, music, dance, art-craft/plastic arts). Interestingly, from this whole sample, only less than 3% actually applied for artistic careers, which suggests that the prevalence of prioritizing artistic activities is higher than commonly assumed and includes not only professional artists, but also many hobbyists, amateurs and dedicated fans. Further, artistic careers applicants prioritize art almost three times more than the total of applicants, suggesting its specificity. After controlling for inconsistency of answer options during the period, prioritizing both Artistic/cultural and Artistic-activities remained temporally stable, as predicted. Despite limitations, overall results supported the hypotheses that artistic behavior is more intrinsically motivated, domain specific, and temporally stable. This plausibly demonstrates that artistic propensity has at least partly an evolved nature.

APA, Harvard, Vancouver, ISO, and other styles

49

Saito, Ryuta, Masayuki Kanamori, and Teiji Tominaga. "DDEL-08. CONVECTION-ENHANCED DELIVERY OF NIMUSTINE HYDROCHLORIDE (ACNU) AGAINST PEDIATRIC DIFFUSE INTRINSIC PONTINE GLIOMAS." Neuro-Oncology 22, Supplement_3 (December 1, 2020): iii285. http://dx.doi.org/10.1093/neuonc/noaa222.043.

Full text

Abstract:

Abstract Diffuse intrinsic pontine gliomas (DIPGs) are amongst the most challenging tumors to treat. Surgery is not an option, the effects of radiation therapy are temporary, and no chemotherapeutic agent has demonstrated significant efficacy. Intracerebral infusion technique of convection-enhanced delivery (CED) for patients with brain tumors could offer a novel approach for effective chemotherapy. We have been working to develop an effective chemotherapy using nimustine hydrochloride (ACNU) with this drug delivery method. After several studies targeting supratentorial recurrent malignant gliomas and recurrent gliomas affecting brainstem, we conducted phase 1 study to evaluate the safety of combination of convection-enhanced delivery of nimustine hydrochloride and systemic temozolomide against recurrent gliomas affecting brainstem. In this study, we demonstrated the safety and feasibility of CED of ACNU as well as real time monitoring of drug distribution by mixing ACNU with contrast agent; Gd-DOTA. We also defined the maximum tolerable concentration in this study and proceeded to phase 2 trial against recurrent gliomas affecting brain stem. However, these trials revealed the difficulty of treating pediatric DIPG at the time of recurrence. Therefore, we decided to treat pediatric DIPG cases at their initial diagnosis in the subsequent study. Aiming at obtaining Shonin approval both for intraparenchymal infusion catheter and drug to infuse into brain parenchyma, we are now conducting Phase II physician-led trial against initially diagnosed pediatric DIPG cases.

APA, Harvard, Vancouver, ISO, and other styles

50

Franzen, Delwen L., Sarah A. Gleiss, Christina Berger, Franziska S. Kümpfbeck, Julian J. Ammer, and Felix Felmy. "Development and modulation of intrinsic membrane properties control the temporal precision of auditory brain stem neurons." Journal of Neurophysiology 113, no. 2 (January 15, 2015): 524–36. http://dx.doi.org/10.1152/jn.00601.2014.

Full text

Abstract:

Passive and active membrane properties determine the voltage responses of neurons. Within the auditory brain stem, refinements in these intrinsic properties during late postnatal development usually generate short integration times and precise action-potential generation. This developmentally acquired temporal precision is crucial for auditory signal processing. How the interactions of these intrinsic properties develop in concert to enable auditory neurons to transfer information with high temporal precision has not yet been elucidated in detail. Here, we show how the developmental interaction of intrinsic membrane parameters generates high firing precision. We performed in vitro recordings from neurons of postnatal days 9–28 in the ventral nucleus of the lateral lemniscus of Mongolian gerbils, an auditory brain stem structure that converts excitatory to inhibitory information with high temporal precision. During this developmental period, the input resistance and capacitance decrease, and action potentials acquire faster kinetics and enhanced precision. Depending on the stimulation time course, the input resistance and capacitance contribute differentially to action-potential thresholds. The decrease in input resistance, however, is sufficient to explain the enhanced action-potential precision. Alterations in passive membrane properties also interact with a developmental change in potassium currents to generate the emergence of the mature firing pattern, characteristic of coincidence-detector neurons. Cholinergic receptor-mediated depolarizations further modulate this intrinsic excitability profile by eliciting changes in the threshold and firing pattern, irrespective of the developmental stage. Thus our findings reveal how intrinsic membrane properties interact developmentally to promote temporally precise information processing.

APA, Harvard, Vancouver, ISO, and other styles

Journal articles on the topic 'Temporary Intrinsics'

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles