Relevant bibliographies by topics / Telomere protection, Telomere capping, Yeast

Contents

  1. Journal articles
  2. Dissertations / Theses

Academic literature on the topic 'Telomere protection, Telomere capping, Yeast'

Author: Grafiati
Published: 9 March 2023
Last updated: 10 March 2023

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Telomere protection, Telomere capping, Yeast.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Telomere protection, Telomere capping, Yeast"

1

Bryan, Tracy M. "G-Quadruplexes at Telomeres: Friend or Foe?" Molecules 25, no. 16 (2020): 3686. http://dx.doi.org/10.3390/molecules25163686.

Full text
Abstract:
Telomeres are DNA-protein complexes that cap and protect the ends of linear chromosomes. In almost all species, telomeric DNA has a G/C strand bias, and the short tandem repeats of the G-rich strand have the capacity to form into secondary structures in vitro, such as four-stranded G-quadruplexes. This has long prompted speculation that G-quadruplexes play a positive role in telomere biology, resulting in selection for G-rich tandem telomere repeats during evolution. There is some evidence that G-quadruplexes at telomeres may play a protective capping role, at least in yeast, and that they may
APA, Harvard, Vancouver, ISO, and other styles
2

Singh, Sunitha M., Olga Steinberg-Neifach, I. Saira Mian, and Neal F. Lue. "Analysis of Telomerase in Candida albicans: Potential Role in Telomere End Protection." Eukaryotic Cell 1, no. 6 (2002): 967–77. http://dx.doi.org/10.1128/ec.1.6.967-977.2002.

Full text
Abstract:
ABSTRACT Telomerase is a ribonucleoprotein reverse transcriptase responsible for the maintenance of one strand of telomere terminal repeats. Analysis of the telomerase complex in the budding yeast Saccharomyces cerevisiae has revealed the presence of one catalytic protein subunit (Est2p/TERT) and at least two noncatalytic components (Est1p and Est3p). The genome of the pathogenic yeast Candida albicans contains putative orthologues of all three telomerase components. Disruption of each homologue resulted in significant but distinct telomere dysfunction in Candida. Similar to S. cerevisiae, the
APA, Harvard, Vancouver, ISO, and other styles
3

Churikov, Dmitri, Chao Wei, and Carolyn M. Price. "Vertebrate POT1 Restricts G-Overhang Length and Prevents Activation of a Telomeric DNA Damage Checkpoint but Is Dispensable for Overhang Protection." Molecular and Cellular Biology 26, no. 18 (2006): 6971–82. http://dx.doi.org/10.1128/mcb.01011-06.

Full text
Abstract:
ABSTRACT Although vertebrate POT1 is thought to play a role in both telomere capping and length regulation, its function has proved difficult to analyze. We therefore generated a conditional cell line that lacks wild-type POT1 but expresses an estrogen receptor-POT1 fusion. The cells grow normally in tamoxifen, but drug removal causes loss of POT1 from the telomere, rapid cell cycle arrest, and eventual cell death. The arrested cells have a 4N DNA content, and addition of caffeine causes immediate entry into mitosis, suggesting a G2 arrest due to an ATM- and/or ATR-mediated checkpoint. γH2AX a
APA, Harvard, Vancouver, ISO, and other styles
4

Xu, Ling, Ruben C. Petreaca, Hovik J. Gasparyan, Stephanie Vu, and Constance I. Nugent. "TEN1 Is Essential for CDC13-Mediated Telomere Capping." Genetics 183, no. 3 (2009): 793–810. http://dx.doi.org/10.1534/genetics.109.108894.

Full text
Abstract:
Telomere binding proteins protect chromosome ends from degradation and mask chromosome termini from checkpoint surveillance. In Saccharomyces cerevisiae, Cdc13 binds single-stranded G-rich telomere repeats, maintaining telomere integrity and length. Two additional proteins, Ten1 and Stn1, interact with Cdc13 but their contributions to telomere integrity are not well defined. Ten1 is known to prevent accumulation of aberrant single-stranded telomere DNA; whether this results from defective end protection or defective telomere replication is unclear. Here we report our analysis of a new group of
APA, Harvard, Vancouver, ISO, and other styles
5

Lamm, Noa, Shhadeh Bsoul, Majdi M. Kabaha, and Yehuda Tzfati. "“Poisoning” yeast telomeres distinguishes between redundant telomere capping pathways." Chromosoma 121, no. 6 (2012): 613–27. http://dx.doi.org/10.1007/s00412-012-0385-6.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

DuBois, Michelle L., Zara W. Haimberger, Martin W. McIntosh, and Daniel E. Gottschling. "A Quantitative Assay for Telomere Protection in Saccharomyces cerevisiae." Genetics 161, no. 3 (2002): 995–1013. http://dx.doi.org/10.1093/genetics/161.3.995.

Full text
Abstract:
Abstract Telomeres are the protective ends of linear chromosomes. Telomeric components have been identified and described by their abilities to bind telomeric DNA, affect telomere repeat length, participate in telomeric DNA replication, or modulate transcriptional silencing of telomere-adjacent genes; however, their roles in chromosome end protection are not as well defined. We have developed a genetic, quantitative assay in Saccharomyces cerevisiae to measure whether various telomeric components protect chromosome ends from homologous recombination. This “chromosomal cap” assay has revealed t
APA, Harvard, Vancouver, ISO, and other styles
7

Dubruille, R., and B. Loppin. "Protection of Drosophila chromosome ends through minimal telomere capping." Journal of Cell Science 128, no. 10 (2015): 1969–81. http://dx.doi.org/10.1242/jcs.167825.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Larrivée, Michel, and Raymund J. Wellinger. "Telomerase- and capping-independent yeast survivors with alternate telomere states." Nature Cell Biology 8, no. 7 (2006): 741–47. http://dx.doi.org/10.1038/ncb1429.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Kibe, Tatsuya, Yuuki Ono, Koichiro Sato, and Masaru Ueno. "Fission Yeast Taz1 and RPA Are Synergistically Required to Prevent Rapid Telomere Loss." Molecular Biology of the Cell 18, no. 6 (2007): 2378–87. http://dx.doi.org/10.1091/mbc.e06-12-1084.

Full text
Abstract:
The telomere complex must allow nucleases and helicases to process chromosome ends to make them substrates for telomerase, while preventing these same activities from disrupting chromosome end-protection. Replication protein A (RPA) binds to single-stranded DNA and is required for DNA replication, recombination, repair, and telomere maintenance. In fission yeast, the telomere binding protein Taz1 protects telomeres and negatively regulates telomerase. Here, we show that taz1-d rad11-D223Y double mutants lose their telomeric DNA, indicating that RPA (Rad11) and Taz1 are synergistically required
APA, Harvard, Vancouver, ISO, and other styles
10

Ueno, Masaru. "Exploring Genetic Interactions with Telomere Protection Gene pot1 in Fission Yeast." Biomolecules 13, no. 2 (2023): 370. http://dx.doi.org/10.3390/biom13020370.

Full text
Abstract:
The regulation of telomere length has a significant impact on cancer risk and aging in humans. Circular chromosomes are found in humans and are often unstable during mitosis, resulting in genome instability. Some types of cancer have a high frequency of a circular chromosome. Fission yeast is a good model for studying the formation and stability of circular chromosomes as deletion of pot1 (encoding a telomere protection protein) results in rapid telomere degradation and chromosome fusion. Pot1 binds to single-stranded telomere DNA and is conserved from fission yeast to humans. Loss of pot1 lea
APA, Harvard, Vancouver, ISO, and other styles

Dissertations / Theses on the topic "Telomere protection, Telomere capping, Yeast"

1

ANBALAGAN, SAVANI. "Role of saccharomyces cerevisiae Rif1 and Rif2 proteins in protection of telomeres." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2013. http://hdl.handle.net/10281/43717.

Full text
Abstract:
Eukaryotic cells distinguish their chromosome ends from accidental DNA double-strand breaks (DSBs) by packaging them into protective structures called telomeres that prevent DNA repair/recombination activities. In this work, we investigated the role of key telomeric proteins in protecting Saccharomyces cerevisiae telomeres from degradation. We show that the shelterin-like proteins Rif1, Rif2, and Rap1 inhibit nucleolytic processing at both de novo and native telomeres during G1 and G2 cell cycle phases, with Rif2 and Rap1 showing the strongest effects. Also Yku prevents telomere resection in G
APA, Harvard, Vancouver, ISO, and other styles
2

Karpov, Victor. "A study on telomere protection and telomerase-and-cap-independent mechanisms of telomere maintenance in yeast Saccharomyces cerevisiae." Mémoire, Université de Sherbrooke, 2008. http://savoirs.usherbrooke.ca/handle/11143/3940.

Full text
Abstract:
An SGA approach to discover cdc13-1ts supressors. Telomeres, the DNA-protein complexes at the end of eukaryotic chromosomes, are essential for chromosomal stability. In yeast, the telomeric single-strand binding protein Cdc13p has multiple important roles related to telomere maintenance: (1) telomeric"capping"--protection of telomeres by forming complexes with yKu70/80 and with Stn1p/Ten1p; (2) positive regulation of telomere replication via interaction with Est1p, which is a part of telomerase; (3) negative regulation of telomerase by the recruitment of telomere elongation suppressors Stn1p a
APA, Harvard, Vancouver, ISO, and other styles
3

Song, Xiangyu. "Telomere Protection and Maintenance in Arabidopsis thaliana." Thesis, 2010. http://hdl.handle.net/1969.1/ETD-TAMU-2010-05-7815.

Full text
Abstract:
Telomeres are the physical ends of linear chromosomes in eukaryotes. Telomeres not only protect chromosome ends from being recognized as double-strand breaks but also maintain the chromosome terminal sequences. These processes involve a number of telomere-related proteins. A major challenge in the field is to elucidate the full constitution of telomere-associated proteins and to understand how different protein complexes are regulated at chromosome termini. Here, I report the identification and characterization of STN1 (Suppressor of cdc thirteen, 1), CTC1 (Conserved Telomere maintenance Compo
APA, Harvard, Vancouver, ISO, and other styles
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography