Relevant bibliographies by topics / TEC15

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'TEC15'

Author: Grafiati
Published: 4 June 2021
Last updated: 13 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'TEC15.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "TEC15"

1

Köhler, Tim, Stefanie Wesche, Naimeh Taheri, Gerhard H. Braus, and Hans-Ulrich Mösch. "Dual Role of the Saccharomyces cerevisiae TEA/ATTS Family Transcription Factor Tec1p in Regulation of Gene Expression and Cellular Development." Eukaryotic Cell 1, no. 5 (October 2002): 673–86. http://dx.doi.org/10.1128/ec.1.5.673-686.2002.

Full text
Abstract:
ABSTRACT In Saccharomyces cerevisiae, the transcription factors Tec1p and Ste12p are required for haploid invasive and diploid pseudohyphal growth. Tec1p and Ste12p have been postulated to regulate these developmental processes primarily by cooperative binding to filamentous and invasion-responsive elements (FREs), which are combined enhancer elements that consist of a Tec1p-binding site (TCS) and an Ste12p-binding site (PRE). They are present in the promoter regions of target genes, e.g., FLO11. Here, we show that Tec1p efficiently activates target gene expression and cellular development in the absence of Ste12p. We further demonstrate that TCS elements alone are sufficient to mediate Tec1p-driven gene expression by a mechanism termed TCS control that is operative even when Ste12p is absent. Mutational analysis of TEC1 revealed that TCS control, FLO11 expression, and haploid invasive growth require the C terminus of Tec1p. In contrast, the Ste12p-dependent FRE control mechanism is sufficiently executed by the N-terminal portion of Tec1p, which contains the TEA/ATTS DNA-binding domain. Our study suggests that regulation of haploid invasive and diploid pseudohyphal growth by Ste12p and Tec1p is not only executed by combinatorial control but involves additional control mechanisms in which Ste12p activates TEC1 expression via clustered PREs and where Tec1p regulates expression of target genes, e.g., FLO11, by TCS control.
APA, Harvard, Vancouver, ISO, and other styles
2

Patel, Mitul, Daniel Schwendemann, Giorgia Spigno, Shiyu Geng, Linn Berglund, and Kristiina Oksman. "Functional Nanocomposite Films of Poly(Lactic Acid) with Well-Dispersed Chitin Nanocrystals Achieved Using a Dispersing Agent and Liquid-Assisted Extrusion Process." Molecules 26, no. 15 (July 28, 2021): 4557. http://dx.doi.org/10.3390/molecules26154557.

Full text
Abstract:
The development of bio-based nanocomposites is of high scientific and industrial interest, since they offer excellent advantages in creating functional materials. However, dispersion and distribution of the nanomaterials inside the polymer matrix is a key challenge to achieve high-performance functional nanocomposites. In this context, for better dispersion, biobased triethyl citrate (TEC) as a dispersing agent in a liquid-assisted extrusion process was used to prepare the nanocomposites of poly (lactic acid) (PLA) and chitin nanocrystals (ChNCs). The aim was to identify the effect of the TEC content on the dispersion of ChNCs in the PLA matrix and the manufacturing of a functional nanocomposite. The nanocomposite film’s optical properties; microstructure; migration of the additive and nanocomposites’ thermal, mechanical and rheological properties, all influenced by the ChNC dispersion, were studied. The microscopy study confirmed that the dispersion of the ChNCs was improved with the increasing TEC content, and the best dispersion was found in the nanocomposite prepared with 15 wt% TEC. Additionally, the nanocomposite with the highest TEC content (15 wt%) resembled the mechanical properties of commonly used polymers like polyethylene and polypropylene. The addition of ChNCs in PLA-TEC15 enhanced the melt viscosity, as well as melt strength, of the polymer and demonstrated antibacterial activity.
APA, Harvard, Vancouver, ISO, and other styles
3

Baur, M., R. K. Esch, and B. Errede. "Cooperative binding interactions required for function of the Ty1 sterile responsive element." Molecular and Cellular Biology 17, no. 8 (August 1997): 4330–37. http://dx.doi.org/10.1128/mcb.17.8.4330.

Full text
Abstract:
The Ste12p transcription factor controls the expression of Ty1 transposable element insertion mutations and genes whose products are required for mating in Saccharomyces cerevisiae. The binding site for Ste12p is a consensus DNA sequence known as a pheromone response element (PRE). Upstream activating sequences (UASs) derived from known Ste12p-dependent genes have previously been characterized to require either multiple PREs or a single PRE coupled to a binding site for a second protein. The Ste12p-dependent UAS from Ty1, called a sterile response element (SRE), is of the second type and is comprised of a PRE and an adjacent TEA (TEF-1, Tec1, and AbaA motif) DNA consensus sequence (TCS). In this report, we show by UV cross-linking analysis that two proteins, Ste12p and a protein with an apparent size of 72 kDa, directly contact the Ty1 SRE. Other experiments show that Tec1p is required for formation of the Ty1 SRE protein-DNA complex and is physically present in the complex. These results establish a direct role for Tec1p in the Ty1 SRE and yet another set of combinatorial interactions that achieve a qualitatively distinct mode of transcriptional regulation with Ste12p.
APA, Harvard, Vancouver, ISO, and other styles
4

Heise, Barbara, Julia van der Felden, Sandra Kern, Mario Malcher, Stefan Brückner, and Hans-Ulrich Mösch. "The TEA Transcription Factor Tec1 Confers Promoter-Specific Gene Regulation by Ste12-Dependent and -Independent Mechanisms." Eukaryotic Cell 9, no. 4 (January 29, 2010): 514–31. http://dx.doi.org/10.1128/ec.00251-09.

Full text
Abstract:
ABSTRACT In Saccharomyces cerevisiae, the TEA transcription factor Tec1 is known to regulate target genes together with a second transcription factor, Ste12. Tec1-Ste12 complexes can activate transcription through Tec1 binding sites (TCSs), which can be further combined with Ste12 binding sites (PREs) for cooperative DNA binding. However, previous studies have hinted that Tec1 might regulate transcription also without Ste12. Here, we show that in vivo, physiological amounts of Tec1 are sufficient to stimulate TCS-mediated gene expression and transcription of the FLO11 gene in the absence of Ste12. In vitro, Tec1 is able to bind TCS elements with high affinity and specificity without Ste12. Furthermore, Tec1 contains a C-terminal transcriptional activation domain that confers Ste12-independent activation of TCS-regulated gene expression. On a genome-wide scale, we identified 302 Tec1 target genes that constitute two distinct classes. A first class of 254 genes is regulated by Tec1 in a Ste12-dependent manner and is enriched for genes that are bound by Tec1 and Ste12 in vivo. In contrast, a second class of 48 genes can be regulated by Tec1 independently of Ste12 and is enriched for genes that are bound by the stress transcription factors Yap6, Nrg1, Cin5, Skn7, Hsf1, and Msn4. Finally, we find that combinatorial control by Tec1-Ste12 complexes stabilizes Tec1 against degradation. Our study suggests that Tec1 is able to regulate TCS-mediated gene expression by Ste12-dependent and Ste12-independent mechanisms that enable promoter-specific transcriptional control.
APA, Harvard, Vancouver, ISO, and other styles
5

Staib, Peter, Ayfer Binder, Marianne Kretschmar, Thomas Nichterlein, Klaus Schröppel, and Joachim Morschhäuser. "Tec1p-Independent Activation of a Hypha-Associated Candida albicans Virulence Gene during Infection." Infection and Immunity 72, no. 4 (April 2004): 2386–89. http://dx.doi.org/10.1128/iai.72.4.2386-2389.2004.

Full text
Abstract:
ABSTRACT The Tec1p transcription factor is involved in the expression of hypha-specific genes in Candida albicans. Although the induction of the hypha-associated SAP5 gene by serum in vitro depends on Tec1p, deletion of all Tec1p binding site consensus sequences from the SAP5 promoter did not affect its activation. In two different animal models of candidiasis, the SAP5 promoter was induced even in a Δtec1 deletion mutant, demonstrating that the requirement for Tec1p in gene expression in C. albicans depends on the environmental conditions within the host.
APA, Harvard, Vancouver, ISO, and other styles
6

Yang, Fang, Sigrid Eckardt, N. Adrian Leu, K. John McLaughlin, and Peijing Jeremy Wang. "Mouse TEX15 is essential for DNA double-strand break repair and chromosomal synapsis during male meiosis." Journal of Cell Biology 180, no. 4 (February 18, 2008): 673–79. http://dx.doi.org/10.1083/jcb.200709057.

Full text
Abstract:
During meiosis, homologous chromosomes undergo synapsis and recombination. We identify TEX15 as a novel protein that is required for chromosomal synapsis and meiotic recombination. Loss of TEX15 function in mice causes early meiotic arrest in males but not in females. Specifically, TEX15-deficient spermatocytes exhibit a failure in chromosomal synapsis. In mutant spermatocytes, DNA double-strand breaks (DSBs) are formed, but localization of the recombination proteins RAD51 and DMC1 to meiotic chromosomes is severely impaired. Based on these data, we propose that TEX15 regulates the loading of DNA repair proteins onto sites of DSBs and, thus, its absence causes a failure in meiotic recombination.
APA, Harvard, Vancouver, ISO, and other styles
7

Chou, Song, Shelley Lane, and Haoping Liu. "Regulation of Mating and Filamentation Genes by Two Distinct Ste12 Complexes in Saccharomyces cerevisiae." Molecular and Cellular Biology 26, no. 13 (July 1, 2006): 4794–805. http://dx.doi.org/10.1128/mcb.02053-05.

Full text
Abstract:
ABSTRACT The Saccharomyces cerevisiae transcription factor Ste12 controls two distinct developmental programs of mating and filamentation. Ste12 activity is regulated by Fus3 and Kss1 mitogen-activated protein kinases through two Ste12 inhibitors, Dig1 and Dig2. Mating genes are regulated by Ste12 through Ste12 binding sites (pheromone response elements [PREs]), whereas filamentation genes are supposedly regulated by the cooperative binding of Ste12 and Tec1 on a PRE adjacent to a Tec1-binding site (TCS), termed filamentous responsive element (FRE). However, most filamentation genes do not contain an FRE; instead, they all have a TCS. By immunoprecipitation, we show that Ste12 forms two distinct complexes, Ste12/Dig1/Dig2 and Tec1/Ste12/Dig1, both in vivo and in vitro. The two complexes are formed by the competitive binding of Tec1 and Dig2 with Ste12, as Tec1 can compete off Dig2 from Ste12 in vitro and in vivo. In the Tec1/Ste12/Dig1 complex, Tec1 binds to the N terminus of Ste12 and to Dig1 indirectly through Ste12. Tec1 has low basal activity, and its transcriptional activation is provided by the associated Ste12, which is under Dig1 inhibition. Filamentation genes are bound by the Tec1/Ste12/Dig1 complex, whereas mating genes are occupied by mostly Ste12/Dig1/Dig2 with some Tec1/Ste12/Dig1. We suggest that Tec1 tethers Ste12 to TCS elements upstream of filamentation genes and defines the filamentation genes as a subset of Ste12-regulated genes.
APA, Harvard, Vancouver, ISO, and other styles
8

Laloux, I., E. Dubois, M. Dewerchin, and E. Jacobs. "TEC1, a gene involved in the activation of Ty1 and Ty1-mediated gene expression in Saccharomyces cerevisiae: cloning and molecular analysis." Molecular and Cellular Biology 10, no. 7 (July 1990): 3541–50. http://dx.doi.org/10.1128/mcb.10.7.3541.

Full text
Abstract:
Ty and Ty-mediated gene expression observed in haploid cells of Saccharomyces cerevisiae depends on several determinants, some of which are required for the expression of haploid-specific genes. We report here the cloning and molecular analysis of TEC1. TEC1 encodes a 486-amino-acid protein that is a trans-acting factor required for full Ty1 expression and Ty1-mediated gene activation. However, mutation or deletion of the TEC1 gene had little effect on total Ty2 transcript levels. Our analysis provides clear evidence that TEC1 is not involved in mating or sporulation processes. Unlike most of the proteins involved in Ty and adjacent gene expression, the product of TEC1 has no known cellular function. Although there was no mating-type effect on TEC1 expression, our results indicate that the TEC1 and the a/alpha diploid controls on Ty1 expression are probably not cumulative.
APA, Harvard, Vancouver, ISO, and other styles
9

Laloux, I., E. Dubois, M. Dewerchin, and E. Jacobs. "TEC1, a gene involved in the activation of Ty1 and Ty1-mediated gene expression in Saccharomyces cerevisiae: cloning and molecular analysis." Molecular and Cellular Biology 10, no. 7 (July 1990): 3541–50. http://dx.doi.org/10.1128/mcb.10.7.3541-3550.1990.

Full text
Abstract:
Ty and Ty-mediated gene expression observed in haploid cells of Saccharomyces cerevisiae depends on several determinants, some of which are required for the expression of haploid-specific genes. We report here the cloning and molecular analysis of TEC1. TEC1 encodes a 486-amino-acid protein that is a trans-acting factor required for full Ty1 expression and Ty1-mediated gene activation. However, mutation or deletion of the TEC1 gene had little effect on total Ty2 transcript levels. Our analysis provides clear evidence that TEC1 is not involved in mating or sporulation processes. Unlike most of the proteins involved in Ty and adjacent gene expression, the product of TEC1 has no known cellular function. Although there was no mating-type effect on TEC1 expression, our results indicate that the TEC1 and the a/alpha diploid controls on Ty1 expression are probably not cumulative.
APA, Harvard, Vancouver, ISO, and other styles
10

Bao, Marie Z., Teresa R. Shock, and Hiten D. Madhani. "Multisite Phosphorylation of the Saccharomyces cerevisiae Filamentous Growth Regulator Tec1 Is Required for its Recognition by the E3 Ubiquitin Ligase Adaptor Cdc4 and Its Subsequent Destruction In Vivo." Eukaryotic Cell 9, no. 1 (January 2010): 31–36. http://dx.doi.org/10.1128/ec.00250-09.

Full text
Abstract:
ABSTRACT In Saccharomyces cerevisiae, the pheromone-induced ubiquitylation and degradation of the filamentation pathway-specific activator, Tec1, suppresses cross talk between the mating and filamentous growth mitogen-activated protein kinase (MAPK) pathways. The mating pathway MAPK, Fus3, phosphorylates Tec1, resulting in its recognition by the SCF (for Skp1, Cullin, F-box containing) E3 ubiquitin ligase complex, leading to its proteolysis. Previously, it was found that Tec1 destruction requires phosphorylation on threonine 273 (T273). T273 is embedded in the sequence LLpTP, which is identical to the canonical binding site for Cdc4, a conserved F-box substrate adaptor for the SCF complex. However, recent work on both Cdc4 and the human Cdc4 ortholog Fbw7 has shown that a second substrate phosphorylation can be required for optimal Cdc4 binding in vitro. We report here that high-affinity binding of recombinant Cdc4 to Tec1 phosphopeptides requires phosphorylation of not only T273 but also a second site, T276. Significantly, both phospho-sites on Tec1 and a conserved basic pocket on Cdc4 are critical for Tec1 proteolysis in response to pheromone treatment of cells, establishing a role for two-phosphate recognition by yeast Cdc4 in substrate targeting in vivo.
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "TEC15"

1

Killefer, Morgan. "Whisker Growth Induced by Gamma Radiation on Glass Coated with Sn Thin Films." University of Toledo / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1501783073245894.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Sehnal, Miriam. "Struktur und Funktion des TEA/ATTS- Transkriptionsfaktors Tec1p von Candida albicans." kostenfrei, 2008. http://d-nb.info/98945004X/34.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Kern, Sandra [Verfasser], and Hans-Ulrich [Akademischer Betreuer] Mösch. "Kernimport des TEAD-Transkriptionsfaktors Tec1 aus Saccharomyces cerevisiae / Sandra Kern. Betreuer: Hans-Ulrich Mösch." Marburg : Philipps-Universität Marburg, 2011. http://d-nb.info/1014851580/34.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Bao, Marie Zimei. "Elucidating the role of Tec1 in the maintenance of signaling specificity in Saccharomyces cerevisiae." Diss., Search in ProQuest Dissertations & Theses. UC Only, 2008. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3297794.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Okutman, Özlem. "Genetics of male infertility : genes implicated in non-obstructive azoospermia and severe oligozoospermia." Thesis, Strasbourg, 2015. http://www.theses.fr/2015STRAJ049/document.

Full text
Abstract:
Parmi les couples avec un projet parental, le facteur masculin d’infertilité est responsable d’environ 20%. Malgré de longues années d’activités d’assistance médicale à la procréation, un nombre important de cas reste idiopathiques. Considérant le nombre élevé des gènes potentiellement impliqués dans la gamétogenèse, il est fort probable que la majorité des formes ‘idiopathiques’ sont d’origine génétique. Dans l'étude présente, nous avons d’identifier deux nouveaux gènes impliqués dans une infertilité masculine. Nos données suggèrent que la mutation dans TEX15 puisse corréler avec une diminution du nombre de spermatozoïdes au fil du temps. Un test diagnostique identifiant la mutation chez un patient pourrait fournir une indication d’organiser au plus tôt une cryopréservation du sperme. On a aussi identifié MAGEB4 liées à l’X comme un nouveau gène impliqué dans une infertilité masculine héritée. Cette étude fournit le premier indice sur la fonction physiologique d'une protéine MAGE
Among couples with a desire for a child, male factor is responsible approximately 20%. Despite long years of assisted reproductive activities, a significant number of cases remain idiopathic. Considering the high predicted number of genes involved in male gametogenesis, it is likely that most ‘idiopathic’ forms may have a genetic origin. In the present study, we have defined two new genes implicated in male infertility. Our data suggested that a nonsense mutation in TEX15 correlates with a decrease in sperm count over time. A diagnostic test identifying the mutation in man could provide an indication of spermatogenic failure and prompt patients to undertake sperm cryopreservation at an early age. We also identified MAGEB4 as a new X-linked gene involved in an inherited male infertility. This study provides the first clue on the physiological function of a MAGE protein
APA, Harvard, Vancouver, ISO, and other styles
6

Köhler, Tim. "Regulation of growth and development by the small GTPase Cdc42p and the transcription factor Tec1p in Saccharomyces cerevisiae." [S.l. : s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=969652704.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Freire, Fernanda [UNESP]. "Expressão dos genes ALS3, HWP1, BCR1, TEC1, CPH1 e EFG1 de Candida albicans em biofilmes após inativação fotodinâmica." Universidade Estadual Paulista (UNESP), 2017. http://hdl.handle.net/11449/152319.

Full text
Abstract:
Submitted by Fernanda Freire null (fernanda.freire@fosjc.unesp.br) on 2017-12-13T19:59:30Z No. of bitstreams: 1 Tese - Fernanda Freire.pdf: 1272262 bytes, checksum: 11df7d222fe968088750e08ceb6fa488 (MD5)
Submitted by Fernanda Freire null (fernanda.freire@fosjc.unesp.br) on 2017-12-14T11:25:01Z No. of bitstreams: 1 Tese - Fernanda Freire.pdf: 1272262 bytes, checksum: 11df7d222fe968088750e08ceb6fa488 (MD5)
Submitted by Fernanda Freire null (fernanda.freire@fosjc.unesp.br) on 2017-12-14T13:50:30Z No. of bitstreams: 1 Tese - Fernanda Freire.pdf: 1272262 bytes, checksum: 11df7d222fe968088750e08ceb6fa488 (MD5)
Approved for entry into archive by Silvana Alvarez null (silvana@ict.unesp.br) on 2017-12-14T18:37:35Z (GMT) No. of bitstreams: 1 freire_f_dr_sjc.pdf: 1272262 bytes, checksum: 11df7d222fe968088750e08ceb6fa488 (MD5)
Made available in DSpace on 2017-12-14T18:37:35Z (GMT). No. of bitstreams: 1 freire_f_dr_sjc.pdf: 1272262 bytes, checksum: 11df7d222fe968088750e08ceb6fa488 (MD5) Previous issue date: 2017-11-30
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Os micro-organismos estão se tornando cada vez mais resistentes aos antimicrobianos e cepas de Candida albicans resistentes aos antifúngicos tem sido isoladas, assim, torna-se importante e necessário a realização de pesquisas que avaliem os efeitos de novos métodos terapêuticos, como a inativação fotodinâmica antimicrobiana (aPDI). Assim, o objetivo deste estudo foi verificar os efeitos da inativação fotodinâmica sobre biofilmes de Candida albicans, avaliando seus efeitos sobre a expressão dos genes TEC1 (fator de transcrição), HWP1 (proteína de parede celular das hifas), EFG1 (regulador transcricional relacionado com a morfogênese), BCR1 (regulador da formação de biofilme e da parede celular), CPH1 (regulador transcricional envolvido na morfogênese) e ALS3 (adesina) de C. albicans. Foram avaliadas 30 amostras isoladas de pacientes portadores de HIV e 30 amostras de pacientes com estomatite protética, quanto a produção de biofilme, peso seco e filamentação. Destas, foram selecionadas as amostras mais virulentas de cada grupo que apresentaram melhor capacidade de formação de biofilme e filamentação. Assim, foi utilizada uma amostra clínica de C. albicans isolada de paciente portador de HIV, uma amostra clínica de C. albicans isolada de paciente com estomatite protética e uma cepa padrão ATCC 18804. A quantificação da expressão dos genes foi relacionada à produção desses genes nas amostras clínicas e na cepa de referência utilizando-se ensaio de PCR em tempo real. Para a aPDI, foram utilizados os fotossensibilizadores azul de metileno a 300 μM e eritrosina a 400 μM sensibilizados com laser de Índio-Gálio-Alumínio-Fósforo de baixa potência (vermelho visível, 660 nm) e LED verde (532 ± 10 nm), respectivamente. Foram avaliados quatro grupos experimentais para a aPDI: a) F+L+: sensibilização com o corante e irradiação com luz; b) F+L-: somente tratamento com o fotossensibilizador; c) F-L+: somente irradiação com luz e d) F-L-: sem sensibilização com o corante e ausência de luz. Os resultados foram analisados por t-test, com um nível de significância de 5%. Após a análise fenotípica, as amostras Ca30 e 39S foram selecionadas para a realização da aPDI. Como esperado, apenas para o grupo F+L+, quando comparado com o grupo F-L-, todos os genes analisados foram sub expressos após a aPDI. O fold-decrease para os genes ALS3, HWP1, BCR1, TEC1, CPH1 e EFG1 foram 0,73; 0,39; 0,77; 0,71; 0,67 e 0,60; para laser, respectivamente, e 0,66; 0,61; 0,50; 0,43; 0,54 e 0,66; para LED, respectivamente. Pode-se concluir que a aPDI mostrou uma redução na expressão dos genes de C. albicans, sugerindo a diminuição de sua virulência.
Micro-organisms are becoming increasingly resistant to antimicrobial agents and Candida albicans resistant strains to antifungal has been isolated, so it is important and necessary to carry out studies that evaluates the effects of new therapeutic methods, such as antimicrobial photodynamic inactivation (aPDI). The objective of this study was verify the effects of aPDI on C. albicans biofilms, evaluating its effects on genes expression: TEC1 (transcription factor), HWP1 (cell wall protein hyphae), EFG1 (transcriptional regulator related to morphogenesis), BCR1 (regulator of biofilm formation and cell wall), CPH1 (transcriptional regulator involved in morphogenesis) and ALS3 (adhesin) of C. albicans. Were evaluated 30 samples isolated from patients with HIV and 30 samples from patients with denture stomatitis, as the production of biofilm, dry weight and filamentation. Of these, the most virulent strains of each group that presented better biofilm formation capacity and filamentation were selected. Therefore, were used a clinical sample of C. albicans isolated from HIV positive patient, a clinical sample of C. albicans isolated from patient with denture stomatitis and a standard strain ATCC 18804. The quantification of gene expression was related to the production of these genes in clinical samples and in the reference strain using PCR assay in real time. For aPDI, were used the photosensitizer methylene blue at 300 uM and erythrosine at 400 uM, sensitized with low power laser Indium-Gallium-AluminumPhosphorus (visible red, 660 nm) and green LED (532 ± 10 nm), respectively. Were evaluated four groups for aPDI: a) P+L+: sensitization with the photosensitizer and irradiation with light; b) P+L-: only treatment with the photosensitizer; c) P-L+: only irradiation with light and d) P-L-: without sensitization with the dye and absence of light. The results were analyzed by t-test, with a significance level of 5%. After the phenotypic analysis, the samples Ca30 and 39 S were selected for aPDI . As expected, only in the group P+L+ when compared with the group P-L-, all analyzed genes were downregulated after aPDI. The fold-decrease for the genes ALS3, HWP1, BCR1, TEC1, CPH1 and EFG1, were 0.73, 0.39, 0.77, 0.71, 0.67 and 0.60, for laser, respectively, and 0.66, 0.61, .050, 0.43, 0.54 and 0.66, for LED, respectively. It could be concluded that aPDI showed a reduction in the expression of C. albicans genes, suggesting its virulence decrease.
2013/22897-2
APA, Harvard, Vancouver, ISO, and other styles
8

Freire, Fernanda. "Expressão dos genes ALS3, HWP1, BCR1, TEC1, CPH1 e EFG1 de Candida albicans em biofilmes após inativação fotodinâmica /." São José dos Campos, 2017. http://hdl.handle.net/11449/152319.

Full text
Abstract:
Orientador: Antonio Olavo Cardoso Jorge
Banca: Juliana Campos Junqueira
Banca: Graziella Nuernberg Back Brito
Banca: Martha Simões Ribeiro
Banca: Célia Regina Gonçalves e Silva
Resumo: Os micro-organismos estão se tornando cada vez mais resistentes aos antimicrobianos e cepas de Candida albicans resistentes aos antifúngicos tem sido isoladas, assim, torna-se importante e necessário a realização de pesquisas que avaliem os efeitos de novos métodos terapêuticos, como a inativação fotodinâmica antimicrobiana (aPDI). Assim, o objetivo deste estudo foi verificar os efeitos da inativação fotodinâmica sobre biofilmes de Candida albicans, avaliando seus efeitos sobre a expressão dos genes TEC1 (fator de transcrição), HWP1 (proteína de parede celular das hifas), EFG1 (regulador transcricional relacionado com a morfogênese), BCR1 (regulador da formação de biofilme e da parede celular), CPH1 (regulador transcricional envolvido na morfogênese) e ALS3 (adesina) de C. albicans. Foram avaliadas 30 amostras isoladas de pacientes portadores de HIV e 30 amostras de pacientes com estomatite protética, quanto a produção de biofilme, peso seco e filamentação. Destas, foram selecionadas as amostras mais virulentas de cada grupo que apresentaram melhor capacidade de formação de biofilme e filamentação. Assim, foi utilizada uma amostra clínica de C. albicans isolada de paciente portador de HIV, uma amostra clínica de C. albicans isolada de paciente com estomatite protética e uma cepa padrão ATCC 18804. A quantificação da expressão dos genes foi relacionada à produção desses genes nas amostras clínicas e na cepa de referência utilizando-se ensaio de PCR em tempo real. Para a aPDI, ... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: Micro-organisms are becoming increasingly resistant to antimicrobial agents and Candida albicans resistant strains to antifungal has been isolated, so it is important and necessary to carry out studies that evaluates the effects of new therapeutic methods, such as antimicrobial photodynamic inactivation (aPDI). The objective of this study was verify the effects of aPDI on C. albicans biofilms, evaluating its effects on genes expression: TEC1 (transcription factor), HWP1 (cell wall protein hyphae), EFG1 (transcriptional regulator related to morphogenesis), BCR1 (regulator of biofilm formation and cell wall), CPH1 (transcriptional regulator involved in morphogenesis) and ALS3 (adhesin) of C. albicans. Were evaluated 30 samples isolated from patients with HIV and 30 samples from patients with denture stomatitis, as the production of biofilm, dry weight and filamentation. Of these, the most virulent strains of each group that presented better biofilm formation capacity and filamentation were selected. Therefore, were used a clinical sample of C. albicans isolated from HIV positive patient, a clinical sample of C. albicans isolated from patient with denture stomatitis and a standard strain ATCC 18804. The quantification of gene expression was related to the production of these genes in clinical samples and in the reference strain using PCR assay in real time. For aPDI, were used the photosensitizer methylene blue at 300 uM and erythrosine at 400 uM, sensitized with low power laser... (Complete abstract click electronic access below)
Doutor
APA, Harvard, Vancouver, ISO, and other styles
9

Ueno, Yukiko. "RGA2, a putative rho-type GTPase-activating protein, is regulated by the transcription factor Tec1 during filamentous growth of Saccharomyces cerevisiae." Thesis, Massachusetts Institute of Technology, 1999. http://hdl.handle.net/1721.1/85375.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Ley, Claudia [Verfasser], and U. [Akademischer Betreuer] Schumacher. "Kausale Zusammenhänge der Expression des Transkriptionsfaktorgens TEC1, des Regulatorgens BCR1 und des Agglutiningens ALS3 in Candida albicans / Claudia Ley ; Betreuer: U. Schumacher." Tübingen : Universitätsbibliothek Tübingen, 2012. http://d-nb.info/1160518025/34.

Full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Books on the topic "TEC15"

1

Tombs, D. J. The evolution of ten15. [London: Controller, H.M.S.O., 1991.

Find full text
APA, Harvard, Vancouver, ISO, and other styles

Book chapters on the topic "TEC15"

1

Gonçalves, João, Helena Soares, Norman L. Eberhardt, Sarah C. R. Lummis, David R. Soto-Pantoja, David D. Roberts, Umadas Maitra, et al. "TEC1 (S. cerevisiae)." In Encyclopedia of Signaling Molecules, 1841. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_101339.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Schubert, Klaus. "Technical translation." In Handbook of Translation Studies, 350–55. Amsterdam: John Benjamins Publishing Company, 2010. http://dx.doi.org/10.1075/hts.1.tec1.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Currie, I. F., J. M. Foster, and P. W. Core. "Ten15: an abstract machine for portable environments." In ESEC '87, 138–48. Berlin, Heidelberg: Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/bfb0022107.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Foster, J. M. "The algebraic specification of a target machine: Ten15." In High-Integrity Software, 198–225. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-5775-9_9.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

"TEC1 (S. cerevisiae)." In Encyclopedia of Signaling Molecules, 5357. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_103785.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "TEC15"

1

E., Salsabila, Ajiwiguna T.A., and Suhendi A. "Performance Evaluation of TEC1-12706 Thermoelectric Cooler Module at Low Temperature Experimentally." In 2019 International Conference on Information and Communications Technology (ICOIACT). IEEE, 2019. http://dx.doi.org/10.1109/icoiact46704.2019.8938437.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Akram, M. N., H. R. Nirmani, and N. D. Jayasundere. "A Study on Thermal and Electrical Characteristics of Thermoelectric Cooler TEC1-127 Series." In 2016 7th International Conference on Intelligent Systems, Modelling and Simulation (ISMS). IEEE, 2016. http://dx.doi.org/10.1109/isms.2016.42.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Kumar, Kameshwar, and Nagesh Thakur. "Dielectric study of Te15(Se100-xBix)85 (x=0, 3, 5 at.%) chalcogenide glasses." In SOLID STATE PHYSICS: Proceedings of the 56th DAE Solid State Physics Symposium 2011. AIP, 2012. http://dx.doi.org/10.1063/1.4710120.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Rojas Cabezas, Percy, Ronaldo De Jesus Souza Ayala, and Mario Bernabe Chauca Saavedra. "Characterization of a prototype of atmospheric water collector using Peltier cells model TEC1-12706." In ICECC 2021: The 4th International Conference on Electronics, Communications and Control Engineering. New York, NY, USA: ACM, 2021. http://dx.doi.org/10.1145/3462676.3462694.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Nguyen, Vinh Q., Jasbinder S. Sanghera, Brian J. Cole, Pablo C. Pureza, Frederic H. Kung, and Ishwar D. Aggarwal. "Fabrication of As-S and As-Se optical fiber with low hydrogen impurities using tellurium tetrachloride (TeC1 4 )." In Integrated Optoelectronics Devices, edited by Yakov S. Sidorin and Ari Tervonen. SPIE, 2003. http://dx.doi.org/10.1117/12.473172.

Full text
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'TEC15' for particular source types:
Journal articles Dissertations / Theses
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography