Dissertations / Theses on the topic 'TCM'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 dissertations / theses for your research on the topic 'TCM.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.
Kalafsky, Michael S. "Repetitive tropical cyclogenesis during TCM-93." Thesis, Monterey, California. Naval Postgraduate School, 1995. http://hdl.handle.net/10945/31451.
Full textKang, Ling 1962. "TCM schemes with partially overlapped signal constellation." Thesis, McGill University, 1991. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=60046.
Full textPereira, Alvaro. "Space-time ring TCM codes on fading channels." Thesis, Staffordshire University, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.402455.
Full textPeh, Lin Kiat. "Performance comparison of two implementations of TCM for QAM." Thesis, Monterey, California. Naval Postgraduate School, 2007. http://hdl.handle.net/10945/55202.
Full textTrellis-Coded Modulation (TCM) is employed with quadrature amplitude modulation (QAM) to provide error correction coding with no expense in bandwidth. There are two common implementations of TCM, namely pragmatic TCM and Ungerboeck TCM. Both schemes employ Viterbi algorithms for decoding but have different code construction. This thesis investigates and compares the performance of pragmatic TCM and Ungerboeck TCM by implementing the Viterbi decoding algorithm for both schemes with 16-QAM and 64-QAM. Both pragmatic and Ungerboeck TCM with six memory elements are considered. Simulations were carried out for both pragmatic and Ungerboeck TCM to evaluate their respective performance. The simulations were done using Matlab software, and an additive white Gaussian noise channel was assumed. The objective was to ascertain that pragmatic TCM, with its reduced-complexity decoding, is more suitable to adaptive modulation than Ungerboeck TCM.
Civilian
Hua, Dong. "3-level latent structure models for TCM data analysis /." View Abstract or Full-Text, 2002. http://library.ust.hk/cgi/db/thesis.pl?COMP%202002%20HUA.
Full textIncludes bibliographical references (leaves 38-41). Also available in electronic version. Access restricted to campus users.
WANG, YANXIA. "HIGH SPEED TURBO TCM OFDM FOR UWB AND POWERLINE SYSTEM." Doctoral diss., University of Central Florida, 2006. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/3198.
Full textPh.D.
Department of Electrical and Computer Engineering
Engineering and Computer Science
Electrical Engineering
Voigt, Lin. "Desempenho de codigos TCM sobre aneis em canais com desvanecimento." [s.n.], 1998. http://repositorio.unicamp.br/jspui/handle/REPOSIP/259801.
Full textDissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Eletrica e de Computação
Made available in DSpace on 2018-07-24T15:39:37Z (GMT). No. of bitstreams: 1 Voigt_Lin_M.pdf: 7354006 bytes, checksum: caf5e02f117e279d59f2fe4044ee1e2a (MD5) Previous issue date: 1998
Resumo: Esta tese apresenta um estudo de desempenho da modulação codificada com códigos convolucionais definidos sobre anéis de inteiro módulo-8 em canais que apresentam desvanecimento. O desempenho é obtido através de simulação computacional e é representado por curvas de taxa de erro de bit (¿BER ¿ Bit Error Rate¿) em função da relação sinal/ruído (¿SNR ¿ Signal to Noise Ratio¿). Conceitos básicos relativos à modulação codificada, caracterização das modulações digitais, modulação codificada através de códigos convolucionais definidos sobre anéis de inteiros e canais que apresentam desvanecimento são também apresentados. Os canais com desvanecimento utilizados para análise de desempenho do TCM sobre anéis são: Rayleigh, Rice e Rádio Móvel via Satélite. Na análise comparativa de desempenho, a seletividade em freqüência para estes canais não é considerada. O desempenho dos TCM sobre anéis são comparados com os esquemas de Ungerboeck equivalentes. Assume-se decodificação suave por máxima verossimilhança utilizando o algoritmo de Viterbi. A utilização de entrelaçadores / desentrelaçadores é explicada e então levada em consideração
Abstract: This thesis presents the performance of coded modulation with convolutional codes over rings of integers modulo-8 on fadinf channels. The performance is obtained by computer simulation and it is given by curves of Bit Error Rate (BER) versus Signal to Noise Ratio (SNR). Basic concepts related with codes modulation, characterization of digital modulations, codes modulation with convolutional codes based on rings of integers and fading channels are presented. The fading channels considered in this study are: Rayleigh, Rice and Land Mobile Satellite Fading Channel. The channels are non selective in frequency. The performance of ring-TCM codes are compared against their Ungerboeck counterparts, with same bandwidth and information data rate. Soft decision maximum-likelihood (ML) decoding using Viterbi algorithm is assumed. The utilization of interleaving/deinterleaving is explained and taken into account in the comparative performance analysis
Mestrado
Mestre em Engenharia Elétrica
Silva, Luciano Barros Cardoso da. "Avaliação da modulação 4D-8PSK TCM em canal não linear." Instituto Tecnológico de Aeronáutica, 2012. http://www.bd.bibl.ita.br/tde_busca/arquivo.php?codArquivo=2217.
Full textRudrangi, Prashanth K. "Linking travel demand management and emission estimation tools." Thesis, This resource online, 1997. http://scholar.lib.vt.edu/theses/available/etd-08252008-162417/.
Full textBohner, Richard H. Jr. "Definition of the mean environmental steering flow for TCM-90 tropical cyclones." Thesis, Monterey, California. Naval Postgraduate School, 1992. http://hdl.handle.net/10945/23615.
Full textA definition for the environmental steering flow in the vicinity of the TCM-90 tropical cyclones is sought by low-pass filtering the Naval Operational Global Atmospheric Prediction System deep-layer mean u- and v- velocity and geopotential height fields. One-dimensional and two-dimensional Fourier decompositions in a limited region (120(o) long) and in a global region are compared with six wavenumber low-pass filters (1-6, 1-9,...,1-21). The measure of goodness of the environmental steering flow interpolated to the storm position was to determine the minimum standard deviation of the propagation vector (defined as difference between storm motion and the steering estimate) for all six storms and the ensemble. The best results were found for either the limited and global region one-dimensional Fourier analyses of the u and v wind fields with a low-pass filter that included only wavenumbers 1 -15. The sic TCM-90 tropical cyclones were subsequently analyzed using this definition of the steering flow to estimate the propagation vectors and to examine the linear shear and relative vorticity gradients of the environmental flow. Except for early stages of storms in low latitude, the low-pass filtered analyses provided steering vectors consistent with the changing translation directions. However, the translation speeds tended to exceed the storm motion and lead to more westward propagation vectors than expected. These propagation vectors tended to be almost perpendicular to the absolute vorticity gradient vector.
Persson, Brage Hedvig, and Andreas Olofsson. "Three-Component Model (TCM) of commitment i svensk kontext : En undersökning av relationen mellan commitment gentemot organisation och närmaste chef." Thesis, Högskolan i Gävle, Avdelningen för socialt arbete och psykologi, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-16912.
Full textThe main purpose of this study was to examine the relationship between organizational commitment and supervisor commitment within a Swedish context using TCM Employee Commitment Survey. Measures were done via a questionnaire distributed to a total of 188 people, with a response rate of 35%. The respondents were employees from three different organizations within the public sector. They were asked to consider different statements regarding their organization, their supervisor and work-related identity. The results showed that if continuance commitment to supervisor is low, affective organizational commitment will be high. The results also showed that when continuance commitment to supervisor was high, continuance organizational commitment was also high. When normative supervisor commitment was high, so was normative organizational commitment. In contrast to previous studies, we found no correlation between affective organizational commitment and affective commitment to supervisor.
Johansson, Mathilda, and Josefin Burström. "Vilken metod inom den traditionella kinesiska medicinen (tcm) kan hjälpa mot stressrelaterade sjukdomar?" Thesis, Högskolan i Skövde, Institutionen för vård och natur, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-8314.
Full textBackground: The public health problem stress has only increased in recent years and several diseases are arisen from stress. There are various stress management techniques but the Chinese medicine is in the stress field not widely used yet. How can Chinese medicine affect stress in individuals? Purpose: What method within the Traditional Chinese medicine (TCM) can help against stress related diseases? Methods: A literature review was conducted with ten selected articles that was analysed and compiled into a report. Results: Acupuncture, acupressure, qigong and tai chi have proved to be good tools for stress management. Only positive results have been measured and it is safe for everyone to practice, so the most people can do it. Further research must be done to investigate if there is the exercise that shows the positive results or whether it is the different Chinese methods. Conclusion: Chinese medicine can be recommended to use in preventing the public health problem stress and to prevent stress related illnesses.
Zheng, Guanhao, and 郑冠濠. "Quantitative survey of pharmacy students' attitudes and use of traditional Chinese medicine (TCM)." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/206583.
Full textpublished_or_final_version
Pharmacology and Pharmacy
Master
Master of Medical Sciences
Dobos, Paul H. "Evaluations of 404 MHz radar wind profiler observations at Okinawa during TCM-90." Thesis, Monterey, California. Naval Postgraduate School, 1992. http://hdl.handle.net/10945/23664.
Full textTAKEDA, Marcos Yuichi. "A Comparison between RS+TCM and LDPC FEC schemes for the G.fast standard." Universidade Federal do Pará, 2016. http://repositorio.ufpa.br/jspui/handle/2011/8036.
Full textApproved for entry into archive by Edisangela Bastos (edisangela@ufpa.br) on 2017-03-28T14:47:19Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissertacao_ComparacaoRS+TCMLDPC.pdf: 893867 bytes, checksum: 0e75a129249af6c11b8245bcb9bf9e5b (MD5)
Made available in DSpace on 2017-03-28T14:47:19Z (GMT). No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissertacao_ComparacaoRS+TCMLDPC.pdf: 893867 bytes, checksum: 0e75a129249af6c11b8245bcb9bf9e5b (MD5) Previous issue date: 2016-02-01
CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
A necessidade de velocidades de conexão a internet cada vez maiores motivou a criação de um novo padrão, G.fast, para DSL (linha digital do assinante), de modo a prover performance semelhante a fibra usando par trançado de fios de cobre. Esta dissertação foca em dois prévios candidatos a esquemas de correção de erro, sendo eles codigos Reed-Solomon com modulaçao codificada em treliça (TCM), de padrões DSL anteriores, e códigos de verificação de paridade de baixa densidade (LDPC), do padrão G.hn para redes residenciais. O objetivo principal é comparar os dois esquemas, de modo a avaliar qual deles tem melhor performance, considerando métricas como poder de correção de erro e custo computacional. Embora o código selecionado para o G.fast já tenha sido RS+TCM, acredita-se que esta decisão foi tendenciosa, já que é sabido que códigos mais recentes como LDPC possuem maior poder correção.
The need for increasing internet connection speeds motivated the creation of a new standard, G.fast, for digital subscriber lines (DSL), in order to provide fiber-like performance using short twisted pair copper wires. This dissertation focuses in the two former candidate codes for the forward error correction (FEC) scheme, namely Reed-Solomon (RS) with trellis-coded modulation (TCM), from previous DSL standards, and low density parity check (LDPC) codes, from the G.hn standard for home networking. The main objective is to compare both schemes, in order to evaluate which of them performs better, considering metrics such as error correction performance and computational cost. Even though the selected code for G.fast was RS with TCM, it is believed that this choice was biased, as a more recent iterative code like LDPC is known to have a better error correction performance.
Albogame, Majed Mohammad. "Enhanced MIMO and TCM-APSK in PTS-OFDMA Wireless System and its Application." University of Toledo / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1556642350076593.
Full textHorwitz, Michael Richard. "A hardware implementation of a Viterbi decoder for a (3,2/3) TCM code." Master's thesis, University of Cape Town, 1997. http://hdl.handle.net/11427/20182.
Full textZaguini, Alessandra. "A relação do potencial de flexibilidade estrutural e cultural na TCM Informática LTDA." Florianópolis, SC, 2002. http://repositorio.ufsc.br/xmlui/handle/123456789/82881.
Full textMade available in DSpace on 2012-10-19T19:08:37Z (GMT). No. of bitstreams: 0Bitstream added on 2014-09-26T01:20:10Z : No. of bitstreams: 1 188744.pdf: 77810193 bytes, checksum: 236b9fb00b2590a26c909e1fafa6f733 (MD5)
Este trabalho teve como objetivo verificar a relação entre o potencial de flexibilidade da estrutura organizacional e o potencial de flexibilidade cultural da TCM Informática Ltda. Adotou-se como método de pesquisa o estudo de caso, sendo que este teve caráter qualitativo. A população foi constituída pelos funcionários da TCM Informática Ltda que apresentavam vínculo empregatício junto a esta, e pertencentes ao nível de diretoria, gerencial e operacional. Para tanto, foram estudadas todas as unidades que pertencem à organização. Foram entrevistados dezessete funcionários, no total de vinte e nove trabalhadores, em virtude da ocorrência de saturação nas respostas concedidas. Os dados foram obtidos junto a fontes primárias, com entrevistas semi-estruturadas, e junto a fontes secundárias, particularmente documentos da própria organização. Conforme a abordagem qualitativa, os dados coletados foram analisados de forma interpretativa e descritiva. Neste sentido, os dados primários foram analisados a partir da técnica de análise de conteúdo e os dados secundários a partir da análise de documento. O potencial de flexibilidade da estrutura organizacional foi identificado por meio de determinadas categorias, como a forma organizacional básica, o sistema de planejamento e controle e os processos de regulação. Estes são divididos em regulação da tarefa, regulação do comportamento, regulação de ajustes mútuos e regulação da tomada de decisão. Por sua vez, o potencial de flexibilidade da cultura organizacional foi identificado a partir da formação da identidade, da liderança, das regras não escritas e da orientação externa. Além disso, o potencial de flexibilidade da estrutura organizacional e o potencial de flexibilidade cultural apresentam subdimensões que foram utilizadas na análise da pesquisa. Com base nos resultados das compreensões destas categorias, relacionou-se o potencial de flexibilidade estrutural e cultural da organização o qual pôde-se identificar uma tendência à congruência entre estas. Além deste fator, a TCM Informática Ltda demonstrou haver características mais particulares de organizações mecanicistas e conservadoras, as quais tendem a dificultar o desenvolvimento do potencial de flexibilidade organizacional.
Wang, Hao [Verfasser], and P. [Akademischer Betreuer] Nick. "The TCM drug Gan Cao stimulates defence in grapevine / Hao Wang ; Betreuer: P. Nick." Karlsruhe : KIT-Bibliothek, 2019. http://d-nb.info/1190179032/34.
Full textYin, Tzyh-Chyang. "Tests of a convective cloud model with soundings during the TCM-90 field experiment." Thesis, Monterey, California. Naval Postgraduate School, 1992. http://hdl.handle.net/10945/28600.
Full textMainali, Miraj. "Performance Evaluation of M-ary APSK using Punctured Trellis Coded Modulation (TCM) for DVB Applications." University of Toledo / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1523281892780375.
Full textJin, Ye. "Quality control of phytopharmaceuticals : assessment and quality control of traditional Chinese medicine." Thesis, Liverpool John Moores University, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327675.
Full textDrivas, Athanasios. "Performance analysis of IEEE 802.11g TCM waveforms transmitted over a channel with pulse-noise interference." Thesis, Monterey, Calif. : Naval Postgraduate School, 2007. http://bosun.nps.edu/uhtbin/hyperion-image.exe/07Jun%5FDrivas.pdf.
Full textThesis Advisor(s): Clark Robertson, Tri Ha. "June 2007." Description based on title screen as viewed on August 14, 2007. Includes bibliographical references (p. 137-138). Also available in print.
Roghell, Carnbring Elvira, and Tove Stålby. "Organisationer i samverkan : Samverkans roll i stadskärnors arbete för ökad attraktivitet." Thesis, Högskolan Väst, Avd för företagsekonomi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:hv:diva-12199.
Full textFor a lot of small cities in Sweden, mentioned in this paper as small towns, there is a strongthreat in terms of external trade. Small cities is defined in our essay as a smaller town withthe characteristic features of a city, so there is a main street in the city and a distinguishingcenter. City centers around the country have been emptied for both organizations andpopulations for decades in relation to the fact that the market has moved outside the city. Theresult of that is the fact that the city centers are at high risk of extinction. In order to reducethis risk, a major effort has been made on cooperation in several parts of the country and alsoin cooperation with our neighboring country Norway. Townships has cooperated to workexternally with other cities and internally to get different actors in the city center to cooperatewith each other. Previous research shows that cooperation is seen as a important ingredient instrengthening of a city center, and it is emphasized that all parties that has an interest in thecity center must cooperate. It is then required that both the public and private sector is a partof the cooperation, which in this paper is called a public-private partnership. In this study, weinvestigated the role of united action in city centers work for increased attractiveness. Ourpurpose of the study is to investigate how organizations work for continued survival in a citycenter. Examinations were made on the work carried out by two small towns in Sweden.Their approach was studied to see how they have avoided or defeated the threat that encirclesthem. In order to achieve our purpose we have conducted a qualitative study where we haveexamined and interpreted the empirical material we collected through the two interviews thatwere made with three respondents who work with center development in the cities wereviewed. Our theoretical reference framework is based on scientific articles and presentscurrent research as well as theories about town center management and methods forachieving successful development in city centers. The empirical basis of the study is based onthe two interviews that we have made with respondents in a career in center development.One of our respondents is a project manager and work with projects in center development,one is a business developer for a municipality in Sweden and the third has a professional roleas a center developer. The theoretical reference framework and empiricism are the startingpoints for our analysis and interpretations. It is because of that we have been able to drawconclusions about city center development and its methods of success. Collaboration isnecessary for a city center to achieve increased attractiveness. It is not enough that differentcity centers collaborates with each other in order to achieve successful city centerdevelopment and increased attractiveness to the city. It is vital that the inner core of the citycooperates with each other, and by that we mean that the city's own trader, property owner,municipality, politicians, residents, consumers, visitors, etc., work together towards commongoals. The two most important factors for collaboration that we could read were commitmentand a common goal. Thanks to the study it is clear that the two factors are crucial forcooperation in reducing the risk of urban deaths.
Bouneaud, Cécile. "Etude des lymphocytes T de mémoire centrale (Tcm) et effectrice (Tem) chez l'homme et chez la souris : voies de différenciation, homéostasie et capacités de réponse secondaire." Paris 6, 2004. http://www.theses.fr/2004PA066020.
Full textIyamabo, Philip Ehizogie. "Exact BER Calculation of TCM-MAPSK using Pairwise Probability of Product Trellis Algorithm for DVB Applications." University of Toledo / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1481247472348161.
Full textLai, Robert. "Systems of innovation : case study on Traditional Chinese Medicine (TCM) organisations' knowledge & capability developments through collaborations." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/systems-of-innovation-case-study-on-traditional-chinese-medicine-tcm-organisations-knowledge--capability-developments-through-collaborations(4ff71e38-6b08-4402-809d-e50d36f34ad9).html.
Full textLima, Neto Adolfo. "Desenvolvimento in vitro de embriões de gatas domésticas, em meio TCM 199 modificado, frescos e previamente congelados." Universidade Federal de Viçosa, 2005. http://locus.ufv.br/handle/123456789/4998.
Full textConselho Nacional de Desenvolvimento Científico e Tecnológico
In this study a total of 48 embryos were used in the compacts morulae, initial blastocysts and blastocysts stages in the degrees I and II, obtained from 14 adult domestic cats. Two animals presented natural manifestation of the oestrus and 12 animals were artificially induced to ovarian activity and ovulation. They received one only application of 150 IU of gonadotropins equine corionic (eCG) and 84h after, one application of 100 IU of gonadotropins human corionic (hCG), and all the animals were coupled naturally. Six days after the first mating, all cats were submitted to laparotomy, and through an adapted transcornual technique the embryos were collected and classified in agreement with IETS (1998). 27 of these were cultivated in a TCM 199 modified with a controlled CO2 atmosphere for 24 hours. The embryos were classified by development stage, quality and blastomeres number, observing a development index until expanded blastocysts in degree I of 77.7% with an average of 161±15,8 blastomeres was reached. In 21 embryos the freezing technique was tested in a commercial medium with 10% of glycerol associated with 0,1molL-1 of sucrose. After the unfreezing, in 37oC water with the same cultivation conditions, a developmental index of 38.1%, was observed until the stage of expanded blastocysts in degree I, with average number of 139.1±11,8 blastomeres. Although the freezing and unfreezing protocols, had reduced the developmental index of feline embryos by 51% and reduce the blastomeres number (P<0.01), it was considerate a viable technique in domestic and wild felines.
Foram utilizados um total de 48 embriões nos estágios de mórula compacta, blastocisto inicial e blastocisto, nos graus I e II, obtidos de 14 gatas domésticas adultas. Dois animais apresentaram manifestação natural do cio e 12 animais foram induzidos artificialmente à atividade ovariana e ovulação. Para tal receberam uma única aplicação de 150 UI de gonadotrofina coriônica eqüina (eCG) e 84h após, uma única aplicação de 100 UI de gonadotrofina coriônica humana (hCG). Todos os animais foram acasalados naturalmente e seis dias após a primeira cópula, todas as gatas foram submetidas a laparotomia, e por meio da técnica de lavagem transcornual adaptada, foram coletados os embriões, os quais foram classificados de acordo com IETS (1998). Vinte e sete foram cultivados em meio TCM 199 modificado, em estufa de CO2, por 24 horas, sendo então avaliados quanto ao seu estágio de desenvolvimento, qualidade e número de blastômeros, observando-se uma taxa de desenvolvimento até o estágio de blastocisto expandido grau I de 77,7%, com um número médio de 161±15,8 blastômeros. Em 21 embriões foi testada a congelabilidade em meio comercial a base de 10% glicerol associado a 0,1molL-1 de sacarose. Após o descongelamento, em banho maria a 37oC, nas mesmas condições de cultivo, observou-se uma taxa de desenvolvimento, até o estágio de blastocisto expandido grau I, de 38,1% com um número médio de 139,1±11,8 blastômeros. Desta forma, embora o protocolo de congelamento e descongelamento tenha reduzido em 51% a taxa de desenvolvimento de embriões felinos, com uma queda (P< 0,01) do número de blastômeros, mostrou-se viável, com promissor uso in vivo em felinos domésticos e silvestres.
Håkansson, Johan, and Madelen Lagin. "Strategic alliances in a town centre : Stakeholder’s perceptions of property owner’s role." Högskolan Dalarna, Kulturgeografi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:du-12640.
Full textPan, Chen Po, and 潘政伯. "Investigating the Impacts and Antecedents of TCM Physicians’ Perceived Effectiveness Toward TCM Technology." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/14480005508651209565.
Full text國立暨南國際大學
資訊管理學系
100
Today, global changes have great influences on healthcare industry. The integration of medical information has become a global trend and a main policy in many developing countries. This study explores the opinions based on a quantitative study of investigating the impacts and attitude of TCM physicians perceived effectiveness toward TCM technology. This article extends existing technology acceptance models to external factor. The purpose of this study is the viewpoint of external factor in Technology Acceptance Model which explains the acceptance of TCM Technology and provides the Actual System Use of TCM physicians. In the end, we would like to provide suggestions for future researchers and expect TCM to have a further development toward IHE. The data were analyzed from questionnaires of 111 TCM physicians, the analysis shows that the technology maturity and government policy positively influence system of maneuverable, society factors positively influence system of functionality, system of maneuverable positively influence quality of healthcare, system of functionality positively influence quality of healthcare and personal information literacy factor have mediating effects between system of functionality and quality of care. Finally, we hope to provide directions to future researches.
Ralston, Carla. "TCM in obstetrics and gynecology." 2004. http://www.ocomlibrary.org/images/PDF/studentpapers/carlaralston.pdf.
Full textLytle, Jill. "TCM and the treatment of asthma." 2005. http://www.ocomlibrary.org/images/PDF/studentpapers/jilllytle.pdf.
Full textLi, Jiun-Yi, and 李雋儀. "Performance Simulation of Pragmatic TCM System." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/33500343459053376591.
Full text國立臺灣大學
電機工程學研究所
88
This paper is about simulation of PTCM system performance in AWGN,using C language and Matlab.The purpose is to understand why we use PTCM,how PTCM system works and how to solve problems of phase ambiguity.
CAI, HOU-SHENG, and 蔡厚笙. "Hardware and VLSI realization of TCM." Thesis, 1992. http://ndltd.ncl.edu.tw/handle/47864300180688170750.
Full textJinnan, Li. "A business plan: TCM health-preservation club." Master's thesis, 2019. http://hdl.handle.net/10071/18896.
Full textO objetivo deste projeto de mestre é desenvolver um Plano de Negócios que poderá abrir um clube de preservação da saúde da Medicina Tradicional Chinesa (MTC), que oferecerá os serviços de métodos da MTC para as consumidoras femininas modernas na área da cidade de Anyang, Província de Henan, China. Devido ao estilo da vida pouco saudável e aos problemas ambientais, os problemas de saúde das mulheres modernas estão a aumentar rapidamente, por isso, a MTC nesta área tem um grande mercado potencial, especialmente direcionada para as mulheres. No entanto, de acordo com um estudo preliminar, percebemos rapidamente que todas clínicas ou clubes locais são parecidos e consideram que eles faltam as especialidades e têm um nível mais baixo. Para aproveitar as oportunidades do mercado, analisamos o mercado atual pelos dados macroeconómicos e comparamos os dados macroeconómicos com os dados adquiridos pelo inquérito e pela viagem de campo, decidi organizar um clube da MTC - os serviços novos que pretendem mudar o relacionamento entre as mulheres e o consumo da MTC a qual lhes fornecerá especificamente as soluções projetadas para satisfazer as suas necessidades. O Clube visa utilizar a terapia da MTC para não só resolver os problemas de saúde das mulheres, mas também para melhorar a qualidade de vida delas, até mesmo prolongar a vida. Manifestamos neste plano de negócios que o nosso negócio é capital baixa, ganha rapidamente o benefício e não precisa empréstimo. No primeiro ano, deve atingir um volume de negócios de 47.617 € e um lucro de 4.130€.
Tai, Chun-Nien, and 戴君年. "Design of High-Level TCM for Satellite Communications." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/09565124626431645395.
Full text國立成功大學
電機工程研究所
84
Most satellite communication systems employ a high power amplifier(HPA) driven at or near saturation for better po- wer efficiency. The combination of this HPA and the prece- ding pulse shaping filter leads to a nonlinear channel wi- th memory and results in severe signal distortions: const- ellation warping and clustering. In order to meet the growing demand for high data rates a- nd to utilize the available bandwidth efficiency, further generations of satellite communication equipment should t- ake the advantages of the TCM schemes with high-order sig- nal constellation which can provide both the power and ba- ndwidth efficiency. In this thesis, we investigate and compare the performanc- es of predistorted high- level TCM schemes on the nonlinear satellite channel. Moreover, we design some high-level TC- M with special signal constellations that outperform the conventional PSK or QAM scheme, and yet do not suffer exc- essive degradation due to channel nonlinearities. The res- ults obtained by computer simulation show that a combinat- ion of moderate back-off and simple data predistortion of high-level TCM can considerably improve the robustness to nonlinear ISI.
Hsieh, Jung-Ching, and 謝榮敬. "TCM-assisted Non-orthogonal Multiple Access OFDM Systems." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/69631208471884639286.
Full text國立交通大學
電信工程研究所
104
It is known that non-orthogonal multiple access (NOMA) can provide higher capacity than orthogonal multiple access. In 3GPP, some NOMA schemes have been standardized, known as multiuser-superposition-transmission (MUST). In this thesis, we study MUST schemes and propose a trellis-coded-modulation (TCM) assisted NOMA system. The proposed system consists of a convolutional code operated in bit-level and a cascaded TCM code operated in symbol-level. To have an unequal-error-protection property for near and far users, four-dimensional TCM is used to construct square-shape QAM constellations, providing two transmission rates for the near user. Power allocation is reserved in the proposed scheme, effectively increasing the flexibility in real-word applications. At the receiver, an iterative decoding scheme is conducted with the BCJR algorithm. With the proposed scheme, dependence is not only introduced in the bit level but also in the symbol level in the subcarriers. This will enhance the resisting capability for frequency-selective fading. The proposed scheme requires minimum changes in current LTE specifications and its real-world application is highly feasible. Simulation shows that the proposed method performs much better than the existing NOMA scheme.
Kuo, Shih-Shan, and 郭仕杉. "A Chip Design for TCM Encoder/Decoder system." Thesis, 1994. http://ndltd.ncl.edu.tw/handle/84882337170197028063.
Full text國立成功大學
電機工程研究所
82
Trellis-coded modulation(TCM) is a scheme combining codingnd modulation. It can get significant coding gains withoutncreasing the transmitted power or the required bandwidth.ut the complexity of Viterbi decoder increases correspondingly.or the TCM encoder proposed in this thesis, there are eight pathsn all parallel transitions of the four- state trellis diagram.he VLSI architecture proposed in this thesis has the advantagef TL(Table-Lookup) method, that it needs only a clock time toecide the minimum branch metric path of the parallel transition,nd finish the branch metric calculation. On the other hand,t needs much smaller area than TL method. This chip has two working modes: Encoding and Decoding.two-phase pipelining architecture for implementing both encodingnd decoding improves the speed performance of this chip. We usehe standard-cell of CCL provided by CIC(Chip Implementationenter),to finish the chip design on CADENCE OPUS3. This chipas fabricated using TSMC 0.8um technology. The chip size is.43*0.46 cm*cm, it contains 48 PADs and gate count is 15440.he working frequency is 30MHZ, and the data rate is 13.3Mbits/s.
LIN, XIN-HAN, and 林信翰. "Design and Analysis of CL-TCM Buck Converter." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/4ahg47.
Full text國立臺灣科技大學
電子工程系
106
Synchronous Conduction Mode (SCM) buck converter offer Zero-Voltage-Switching (ZVS) but suffer from large output inductor RMS current at light load, which are lowering down the efficiency. Triangular Current Mode (TCM) also offer ZVS and improve the light load efficiency but suffer from large switching frequency variations, which are complicating the EMI filter design and the digital control. As a solution, a Clamp-Switch TCM buck converter can be proposed into this paper, by adding clamp switch to limit the switching frequency variation and analyzing switching time interval to calculate the switch-on time, feasibility can be verified by circuit simulation software. With digital control, a 240 watt rated power, 12 volt output of CL-TCM buck converter prototype can be realized.
Wu, Jau-Ming, and 吳昭明. "Combination Systems of BCM and TCM with Phase Rotational." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/45882888683592671039.
Full text國立成功大學
電機工程研究所
83
Three schemes of combining block-coded modulation (BCM) and trellis-coded modulation (TCM) to get a higher gain for high data transmission rate are proposed. Scheme 1: Signal set partition is a major work in constructing the multi- dimensional TCM system. Since a BCM system of length n can be seen as a set of 2n-dimensional signal points and can be constructed by the multi-level construction method, we propose a systematic way to construct multiple BCM systems and the whole 2n-dimensional signal points are partitioned by these BCM systems. Scheme 2: Since a proper BCM system can approximate the dense lattice, TCM can be constructed based on the proper BCM system. Thus, a higher coding gain can be obtained from both the distance gain of the TCM structure and the density gain of the dense lattice. Theoretically, the asymptotic coding gain can reach 5.27 dB for 8-dimensional case and 7.15 dB for 16-dimensional case. Scheme 3: In constructing TCM system, the whole signal points must be partitioned into two families. We can use two BCM systems to serve as the two families. Since a larger signal constellation is used, the coding gain is higher than scheme 2. For QAM signals, the 90 ? 180 ? and 270 ? phase ambiguity problems must be considered. Three criterions must be satisfied such that the problems can be removed by introducing a differential encoder/decoder. All of the proposed schemes satisfy the three criterions. In summary, three simple and systematic ways to design the coded modulation systems with high asymptotic coding gain for high data rate transmission are proposed and the 90 ? 180 ? and 270 ? phase ambiguity problems are solved.
"Mechanistic and pharmacokinetic studies of novel TCM-Platinum compounds." 2002. http://library.cuhk.edu.hk/record=b6073420.
Full text"May 2002."
Thesis (Ph.D.)--Chinese University of Hong Kong, 2002.
Includes bibliographical references (p. 201-236).
Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.
Mode of access: World Wide Web.
Abstracts in English and Chinese.
李佳勳. "Hardware Architecture Design of Adaptive Equalizer and TCM Decoder." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/rav63b.
Full text國立交通大學
電信工程系所
93
The Single-pair High Speed Digital Subscriber Loop (SHDSL) is the new generation symmetric DSL technique which could supply at most 2.3 Mbps downlink and uplink data rate symmetrically to subscribers on a long loop. However, the InterSymbol Interference (ISI) is severe especially duration the transmission over a long loop. Normal data transmission is impossible without properly taking care of the ISI problem. To assure SHDSL tranceivers to provide full-rate transmission, we need a powerful adaptive equalizer to ease the ISI problem. The decision feedback equalizer is the most often used equalizer for sovling the ISI problem. However, it has the error propagation problem, which will degrade the system performance. To improve the performance, the joint equalization and channel decoding is necessary. Nevertheless, combining the trellis decoder in the decision feedback equalizer will result in high complexity hardware. A powerful equalizer called Tomlinson-Harashima precoder (THP) system was proposed to solve this problem. By use of the procoding technique, the joint equalization and channel decoding can be accomplished by cascade a linear equalizaer and a TCM decoder for channel coding. In this theisis, starting from algorithm design and computer simulation, we design the THP system and TCM decoder hardware architectures according to the G.SHDSL recommendation. The resulting hardware could achieve the maximum 2.3 Mbps data rate under the 50 MHz operation clock. The hardware was verified on the FPGA development board.
Yeh, Yi-Chun, and 葉怡君. "An Investigation on Competence of TCM for BSN Graduates." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/82551233649521622453.
Full text國立台北護理學院
醫護教育研究所
93
The purpose of this study is to explore what a BSN graduate who is going to devote herself/himself to medical field should know about TCM, attitude and skills. Until now there is no study pointing out the knowledge a nursing staff should know about TCM because many sources of nursing textbooks and references are still absorbed from the western. For the lack of a common consensus, the related workers have difficulties in designing courses to fit the needs. In order to understand what difficulties and requirements they face in their practical nursing experience, 31 people, including the consumer, the nursing staff and the clinical instructor, are interviewed by four Focus group symposiums. The result is then discussed by four academic experts in the Panels Discussion. They conclude nine competence of TCM that a BSN graduate should have. Firstly, to understand the basic concepts of TCM, including Yin/Yang, Five Evolutive phases, holistic view, five viscera Six Bowels, meridian, and concept of therapy and health preservation. Secondly, to recognize the cold and hot nature of food. Thirdly, to illustrate the common dietetic care for immune enhancement in the four seasons, postnatal and postoperative physical-regeneration. Fourthly, to illustrate the properties, indications, and administration of common TCM medicine, including: Ginseng, Lycium, Astragalus, Angelicae Sinensis(Tang-Kuei),Chrysanthemum, Pinellia, Zizyphi fructus. Fifthly, to describe the properties, indications, adverse effects, administration of Si-Wu-Tang and Sheng-Hua-Tang. Sixthly, to simultaneously describe basic principles of administering TCM and Western medicine. Seventhly, to describe the indications and modalities of the following techniques: acupuncture, scraping therapy, and cupping. Eighthly, to implement acupressure as a measure for promoting comfort under the following conditions: pain, vomiting, insomnia, palpitation; and the last one, to demonstrate an open mind and cautious attitude to respect consumers using TCM. As follows are the analysis and discussion about TCM, attitude and skills. We sincerely expect the result of the study could make some contribution to TCM nursing education, and effectively raise the nursing quality in the future.
Yu, Jyun-Da, and 余俊達. "Performance Evaluation of Mobile TCM Acupuncture Point Instruction Application." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/61355255879699441711.
Full text義守大學
資訊管理學系
102
In the era of Internet and rapid information technology development today, the advances in technology has greatly changed and improved our lives. The new learning styles are created from E-learning until mobile learning. New generation of learning is more convenient, cheaper and timesaving etc. The major units have imported and worked on improving productivity and learning ability. After a system was introduced, the investigation’s susccess become the subject that cannot be ignored. So this research start to merger and modify IS success and TAM model for creating a new model. It allows us to investigate the intension of users on Mobile TCM Acupuncture Point Instruction Application and see whether they will continue to use it. It uses Information Quality affect perceived usefulness, System Quality affect Perceived Ease of Use and Perceived Usefulness and Perceived Ease of Use affect Willingness Use as research framework. The survey distributed 200 questionnaires which have 177 in effect. The result shows the hypotheses are true after taking descriptive analysis, correlation analysis, reliability Cronbach''s alpha and some other analysis.
Lee, Yu Lien, and 李豫蓮. "Investigation of Sulfur Dioxide Residue on TCM Herbs in Taiwan and Analysis on the Relevant Management Trend of the Nations Commonly Use TCM Herbs." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/40778902023934716250.
Full text大仁科技大學
製藥科技研究所
102
Traditional Chinese Medicines (TCM) has gained international recognition and popularity, sulfur fumigation is used to store TCM herbs in order to meet the increase demand for medicines. Sulfur fumigation has the benefit to keep moist, prevent insects and moulds and preserve colour and freshness, however, trace amount can affect the quality of TCM and human health. China supplied majority of world’s TCM herbs, however over use and incorrect use of sulfur fumigation were often seen in its local market. In 2008 South Korea had set sulfur dioxide residue requirement less than 30 ppm for 266 TCM herbs;in the late 2013, the second supplement of “Chinese Pharmacopoeia 2010 Edition” also comprehensively regulated on all TCM herbs with limits in the range of 150-400ppm. Taiwan annually imports about 36,000 tonnes of TCM herbs, of which 85% imported from China, in this study we found most of the TCM herbs still undergo sulfur fumigation, with Anemarrhena Rhizome and Ginkgo seed exceed the 500ppm limits set by Taiwan Herbal Pharmacopeia. Comparing our results to the previous finding, a reduction of over limit rate but a general raise in the median of sulfur dioxide residues indicate the actual process has been conduct even more frequently, with ever increase attention on the safety of TCM, to avoid sulfur dioxide containing herbs, an appropriate standard base on its nature and usage is necessary to protect the safety of patients and ensure the sustainable development of TCM.
"Novel TCM-Platinum compounds: biological activity, cross-resistance and toxicity." 2001. http://library.cuhk.edu.hk/record=b6073360.
Full textThesis (Ph.D.)--Chinese University of Hong Kong, 2001.
Includes bibliographical references (p. 293-345).
Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.
Mode of access: World Wide Web.
Abstracts in English and Chinese.
CHEN, TSUNG-JEN, and 陳宗仁. "Analysis of Meteorological Factors and TCM Syndromes of Cancer Patients." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/q2h44x.
Full text國立中正大學
資訊工程研究所
107
The correlation between meteorological changes and health has been heavily studied in traditional Chinese medicine for a long time. It is believed that the meteorological factors such as wind, cold, heat, damp, dryness and fire are the main causes for most exogenous syndromes. For example, wind-caused syndromes occur mostly in spring, heat-caused syndromes occur mostly in early summer, damp-caused syndromes occur mostly in late summer, dryness-caused syndromes occur mostly in autumn, and cold-caused syndromes occur mostly in winter. Therefore, this thesis applies data mining techniques, the Pearson correlation coefficient and one-way analysis of variance, to investigate the correlation between the regional meteorological changes and the number of cancer patients for corresponding exogenous syndromes. The research results can facilitate the medical practitioners in Yunlin and Chiayi areas to more thoroughly understand the characteristics of exogenous syndromes of local patients. The research results of this thesis show that heart qi dysfunction (qi stagnation) syndrome, liver fire stagnation syndrome, and liver yang sputum syndrome have a positive correlation with mean temperature; liver fire inflammation syndrome has a negative correlation with air pressure; heart qi resistance (cold condensation) syndrome has a negative correlation with mean wind speed.
Buttgereit, Stephan, and 彭世豐. "The disruptive potential of TCM products for dysmenorrhea treatment in Germany." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/07011254951316323895.
Full text國立政治大學
國際經營管理英語碩士學位學程(IMBA)
104
14.5 million women in Germany between the ages of 15 – 44 are plagued from menstrual pain starting from minor discomfort to major pain and cramps. All those women share the same imperative wish: the pain should stop. We found a disruptive solution that acts as an alternative for synthesized medication and has the potential to revolutionize the market for dysmenorrhea remedies, functional foods with the properties revered of the Traditional Chinese Medicine (TCM). TCM as a method to alleviate menstrual pains has not yet found its way to Germany (and the rest of the European Union). Thus we offer our customers a completely new solution to a problem as old as humanity itself. Our products are all based on TCM ingredients with thousands of years of tradition and successful practice that have also been clinically proven. Just over the last 25 years over a billion women in East Asia have fallen back on using herbs and functional foods of the Traditional Chinese Medicine as their remedy of first choice when comes to menstrual pain and other complaints. The research shows a great market potential for TCM products as a treatment for dysmenorrhea in Germany.
Chang, Chung-Yin, and 張仲尹. "Development and Waveform Analysis of a TCM-Based Pulse Measurement System." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/82096198479304549881.
Full text國立臺灣科技大學
機械工程系
105
Palpation is one of the fundamentals in Traditional Chinese Medicine (TCM). In recent years, plenty researches on this high efficiency holistic health diagnosis method has been conducted. In this paper, a robust pulse measurement system is presented, which is capable of following suit of TCM doctors performing palpation on patient. Our system is comprised of strain gauge based pulse force sensing unit, signal processing circuit which contains amplification and filter, data acquisition system and user interface. The pulse data are recorded for real-time signal display and post-processing. This paper adopt an average waveform calculation technique for retrieving a representative single pulse waveform to avoid subjective error. With the measured pressing depth and force, this paper considers the effects of pulse impedance and takes it as an auxiliary performance index to enhance evaluation of pulse waveforms from a TCM perspective. This paper aim to provide an advance approach to preserve pulse pattern in exceptional precision. By using gamma probability density function to correlate pulse waveform and the retrieved pulse impedance information to create the pulse pattern model. Further, we designed experiments that uses three types of external stimulation on human to generate different pulse pattern for measurement. The results verify the purposed system and pulse pattern modelling method has high reproducibility and effectiveness for various patterns.
"Mechanistic study of herb-drug interactions between oseltamivir and TCM formulae." 2010. http://library.cuhk.edu.hk/record=b5894452.
Full textThesis (M.Phil.)--Chinese University of Hong Kong, 2010.
Includes bibliographical references (leaves 145-166).
Abstracts in English and Chinese.
Table of Contents --- p.I
Acknowledgements --- p.VI
Publications --- p.VII
Abstract (in English) --- p.VIII
Abstract (in Chinese) --- p.X
List of Figures --- p.XII
List of Tables --- p.XVI
List of Abbreviations --- p.XVII
Chapter Chapter One. --- Introduction --- p.1
Chapter 1.1 --- Overview of oseltamivir --- p.1
Chapter 1.1.1 --- General description of oseltamivir --- p.1
Chapter 1.1.2 --- Pharmacological activities of oseltamivir --- p.3
Chapter 1.1.3 --- Pharmacokinetics of oseltamivir --- p.3
Chapter 1.1.3.1 --- Absorption of oseltamivir --- p.4
Chapter 1.1.3.2 --- Distribution of oseltamivir --- p.5
Chapter 1.1.3.3 --- Metabolism of oseltamivir --- p.6
Chapter 1.1.3.4 --- Elimination of oseltamivir --- p.8
Chapter 1.1.4 --- Side effects and toxicities of oseltamivir --- p.9
Chapter 1.2 --- Overview of Chinese medicine formulae CMF1 (Yinqiaosan and Sangjuyin) --- p.9
Chapter 1.2.1 --- Background and clinical use of CMF1 --- p.9
Chapter 1.2.2 --- Quality control of CMF1 by manufacturer --- p.11
Chapter 1.2.3 --- Major active components of CMF1 --- p.12
Chapter 1.3 --- Previous studies on herb-drug interactions between O and CMF1 --- p.18
Chapter 1.4 --- Rationale of the current study --- p.19
Chapter 1.5 --- objectives --- p.19
Chapter Chapter Two. --- Identification and quantification of major marker compounds in Yinqiaosan and Sangiuyin products --- p.20
Chapter 2.1 --- Introduction --- p.20
Chapter 2.2 --- Materials and methods --- p.23
Chapter 2.2.1 --- Chemicals --- p.23
Chapter 2.2.2 --- Instruments --- p.24
Chapter 2.2.3 --- Chromatographic conditions --- p.24
Chapter 2.2.4 --- Preparation of standard solutions --- p.25
Chapter 2.2.5 --- Calibration curves --- p.26
Chapter 2.2.6 --- Validation of the assay method --- p.26
Chapter 2.2.7 --- Sample preparations for Yinqiaosan and Sangjuyin products --- p.27
Chapter 2.2.7.1 --- Sample extraction from Yinqiaosan or Sangjuyin granules --- p.27
Chapter 2.2.7.2 --- Sample extraction from Yinqiaosan or Sangjuyin tablets --- p.27
Chapter 2.2.7.3 --- Sample extraction recoveries --- p.27
Chapter 2.3 --- Results and discussions --- p.28
Chapter 2.3.1 --- Chromatography --- p.28
Chapter 2.3.2 --- Linearity and sensitivity --- p.33
Chapter 2.3.3 --- Accuracy and precision --- p.33
Chapter 2.3.4 --- Stability --- p.36
Chapter 2.3.5 --- Contents of identified active components in commercial available Yinqiaosan or Sangjuyin products and CMF1 --- p.36
Chapter 2.3.6 --- Sample extraction recovery --- p.40
Chapter 2.4 --- Conclusion --- p.43
Chapter Chapter Three. --- Effect of CMF1/CMF1 components on the metabolism of oseltamivir and related mechanistic studies --- p.44
Chapter 3.1 --- Introduction --- p.44
Chapter 3.2 --- Materials and methods --- p.47
Chapter 3.2.1 --- Materials --- p.47
Chapter 3.2.2 --- "Verification of metabolism of O in rat GI tract, plasma and liver microsome" --- p.48
Chapter 3.2.3 --- Inhibition of metabolism of O by CMFl/CMFl components --- p.49
Chapter 3.2.3.1 --- In vitro inhibition of metabolism of O in rat plasma --- p.49
Chapter 3.2.3.2 --- In vitro inhibition of metabolism of O in rat liver microsome (RLM) --- p.49
Chapter 3.2.4 --- Mechanistic study of enzyme inhibition of O in recombinant human Carboxylesterase 1 (hCE 1) --- p.50
Chapter 3.2.5 --- Sample preparation and LC/MS/MS analysis --- p.50
Chapter 3.2.6 --- Data analyses --- p.52
Chapter 3.3 --- Results --- p.53
Chapter 3.3.1 --- "Verification of metabolism of O in rat GI tract, plasma and liver microsome" --- p.53
Chapter 3.3.2 --- Inhibition of metabolism of O by CMF1/CMF1 components --- p.53
Chapter 3.3.2.1 --- Enzyme inhibition of metabolism of O by CMFl/CMF1 components in rat plasma --- p.53
Chapter 3.3.2.2 --- Enzyme inhibition of metabolism of O by CMF1/CMF1 components in rat liver microsome (RLM) --- p.58
Chapter 3.3.2.3 --- Selection of potent enzyme inhibitor from CMF1 --- p.60
Chapter 3.3.4. --- Mechanistic study of enzyme inhibition of O in recombinant human Carboxylesterase 1 (hCE 1) --- p.61
Chapter 3.4 --- Discussions --- p.63
Chapter 3.5 --- Conclusion --- p.74
Chapter Chapter Four. --- Effect of CMFl/CMFl components on the absorption of oseltamivir and related mechanistic studies --- p.75
Chapter 4.1 --- Introduction --- p.75
Chapter 4.2 --- Materials and methods --- p.79
Chapter 4.2.1 --- Materials --- p.79
Chapter 4.2.2 --- PAMPA permeation model --- p.80
Chapter 4.2.2.1 --- Permeation of O and OC in PAMPA --- p.80
Chapter 4.2.2.2 --- Sample preparation and LC/MS/MS analysis --- p.81
Chapter 4.2.2.3 --- Data analysis --- p.81
Chapter 4.2.3 --- Absorption of O in presence of CMF/CMFl components in Caco-2 and MDCK cell monolayer models --- p.82
Chapter 4.2.3.1 --- Cell culture --- p.82
Chapter 4.2.3.2 --- Preparation of loading solutions to the cell models --- p.83
Chapter 4.2.3.3 --- Stability of O in transport buffer --- p.84
Chapter 4.2.3.4 --- Cytotoxicity tests of O and CMFl/CMFl components --- p.84
Chapter 4.2.3.5 --- Transport study in Caco-2 and MDCK monolayer model --- p.85
Chapter 4.2.3.6 --- Sample preparation and LC/MS/MS analysis --- p.86
Chapter 4.2.3.7 --- Data analysis --- p.87
Chapter 4.2.4 --- Absorption of O in presence of CMF 1 in rat in situ single pass intestinal perfusion model --- p.88
Chapter 4.2.4.1 --- Preparation of perfusion solutions --- p.88
Chapter 4.2.4.2 --- Stabilities of O and arctigenin in perfusate --- p.88
Chapter 4.2.4.3 --- Rat in situ single pass intestinal perfusion of O in presence and absence of CMFl and relevant inhibitors --- p.89
Chapter 4.2.4.4 --- Sample preparation and LC/MS/MS analysis --- p.90
Chapter 4.2.4.5 --- Data analysis --- p.90
Chapter 4.3 --- Resul ts --- p.91
Chapter 4.3.1 --- Permeation of O and OC in PAMPA --- p.91
Chapter 4.3.2 --- Absorption of O in presence of CMF/CMF1 components in Caco-2 and MDCK cell monolayer models --- p.92
Chapter 4.3.2.1 --- Stabilities of O in transport buffer --- p.92
Chapter 4.3.2.2 --- Cytotoxicity tests of O and CMF1/CMF1 components in transport buffer --- p.93
Chapter 4.3.2.3 --- Proof of O as a substrate of P-gp by Caco-2 cell model --- p.95
Chapter 4.3.2.4 --- Effect of CMF 1 on the absorption transport of o in Caco-2 cell mode --- p.98
Chapter 4.3.2.5 --- Effect of CMF1 components on the absorption transport of o in Caco-2 cell model --- p.102
Chapter 4.3.2.6 --- Effect of arctigenin on bi-directional transport of o in Caco- 2 cell model --- p.106
Chapter 4.3.2.7 --- Proof of O as a substrate of P-gp by MDCK transfected cell lines --- p.108
Chapter 4.3.2.8 --- Bi-directional transport of O in MDCK-MDR1 cell model --- p.111
Chapter 4.3.2.9 --- Effect of CMF 1 on the absorption transport of O in MDCK-MDR1 cell model --- p.112
Chapter 4.3.3 --- Absorption of O in presence of CMF1 in rat in situ single pass intestinal perfusion model --- p.113
Chapter 4.3.3.1 --- Stabilities of O and arctigenin in the perfusion buffer --- p.113
Chapter 4.3.3.2 --- Intestinal absorption of O in presence and absence of CMF1 in rat in situ intestinal perfusion model --- p.114
Chapter 4.4 --- Discussions --- p.116
Chapter 4.5 --- Conclusion --- p.124
Chapter Chapter Five. --- Preliminary evaluation of antiviral activity of CMFl/CMFl components --- p.125
Chapter 5.1 --- Introduction --- p.125
Chapter 5.2 --- Materials and methods --- p.128
Chapter 5.2.1 --- Materials and animals --- p.128
Chapter 5.2.2 --- Animal treatment --- p.129
Chapter 5.2.3 --- Plasma sample collection and preparation --- p.130
Chapter 5.2.4 --- Evaluation of antiviral activities of CMFl/ CMFl components --- p.130
Chapter 5.2.4.1 --- Plaque reduction assay --- p.131
Chapter 5.2.4.2 --- Optimization of plasma sample dilution ratio --- p.131
Chapter 5.2.5 --- Data analyses --- p.133
Chapter 5.3 --- Results and discussions --- p.135
Chapter 5.3.1 --- Ex vivo evaluation of antiviral activity of CMF1 --- p.135
Chapter 5.3.2 --- In vitro evaluation of antiviral activity of CMF1 major marker compounds --- p.139
Chapter 5.4 --- Conclusion --- p.141
Chapter Chapter Six. --- Overall conclusion --- p.142
References --- p.145