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Dissertations / Theses on the topic 'Tc cells'

Author: Grafiati

Published: 10 December 2022

Last updated: 31 July 2025

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1

BRAMBILLA, TANIA de P. "Desenvolvimento de metodos para marcacao de DMSA pentavalente com sup(99m)Tc e sup(188)Re." reponame:Repositório Institucional do IPEN, 2009. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11516.

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Made available in DSpace on 2014-10-09T12:52:46Z (GMT). No. of bitstreams: 0<br>Made available in DSpace on 2014-10-09T14:02:48Z (GMT). No. of bitstreams: 0<br>Dissertacao (Mestrado)<br>IPEN/D<br>Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP

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2

Lackay, Carolynn Louise. "Evaluation of the labelling and binding efficiency of Tc-99m to red blood cells of patients who are being exposed to a cocktail of anti-tuberculosis drugs." Thesis, Cape Peninsula University of Technology, 2010. http://hdl.handle.net/20.500.11838/1555.

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Thesis (MTech (Radiography (Nuclear Medicine)))--Cape Peninsula University of Technology, 2010<br>Radioactively labelled red blood cells (RBC) are used in various nuclear medicine studies. In order to obtain accurate results when performing these studies, it is of paramount importance that a good binding of the radioactivity (Tc-99m) with the red blood cells is ensured. The literature indicates that certain drugs can influence red cell membrane properties and biochemistry. These drugs can potentially influence the binding of radionuclides to cells. Antibiotics may possibly alter the labelling

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TEODORO, RODRIGO. "Avaliação pré-clínica do análogo da neurotensina(8-13) radiomarcado com sup(99m)Tc: caracterização in vitro e in vivo." reponame:Repositório Institucional do IPEN, 2010. http://repositorio.ipen.br:8080/xmlui/handle/123456789/9538.

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Made available in DSpace on 2014-10-09T12:27:46Z (GMT). No. of bitstreams: 0<br>Made available in DSpace on 2014-10-09T14:05:01Z (GMT). No. of bitstreams: 0<br>Tese (Doutoramento)<br>IPEN/T<br>Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP

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4

Modebe, Emmanuel Obinna. "Extended Cr-51 RBC combined with Tc-99m RBC for the detection and localisation of occult GIT bleeding." Thesis, Stellenbosch : Stellenbosch University, 2014. http://hdl.handle.net/10019.1/86509.

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Thesis (MMed)--Stellenbosch University, 2014.<br>ENGLISH ABSTRACT: Background Occult blood loss from the gastrointestinal tract (GIT), causing iron deficiency often with anaemia, can be diagnostically and therapeutically challenging. This is because the endoscopic and radiologic tests may be negative due to the slow, chronic and intermittent nature of the gastrointestinal bleeding, making timing key in detection and localisation of the bleed. These limitations can be approached using two different radioactive isotopes. Firstly, we tested the sensitivity of extending Cr-51 RBC for 21 days rela

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5

Rodrigues, Michelle Pinheiro. "Avaliação da toxicidade induzida pelos componentes do radiofármaco 99m Tc-MDP em cepa de E. coli AB1157 e células eucarióticas de ratos e humanos." Universidade do Estado do Rio de Janeiro, 2008. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=1601.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>As células dos seres vivos são constantemente ameaçadas por agentes químicos ou físicos que possam causar danos ao DNA. Um dos agentes deste estudo foi o cloreto estanoso (SnCl2), utilizado na medicina nuclear como redutor de um isótopo radioativo do tecnécio, o 99mTc. O SnCl2 é um agente cujo mecanismo de produção de lesões em estruturas celulares envolve a geração de espécies reativas de oxigênio (ERO), tais como o H2O2 e o radical OH. Essas ERO podem causar uma série de doenças, o envelhecimento e até mesmo a morte celular, por

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6

Brunet, Daniel V. "The role of T-cell protein tyrosine phosphatase (TC-PTP) in the nucleus /." Thesis, McGill University, 2005. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=97913.

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The 45kDa isoform of TC-PTP is a ubiquitous, predominantly nuclear protein. Reports demonstrate that it can exist outside the nucleus; however, immunofluorescence and cellular fractionation techniques point to an almost exclusive residence in the nucleus, and even within the nucleolus. Though the conditions of nucleolar enrichment appear to be serum-dependent, and may involve S52 phosphorylation, the exact circumstances necessary for this localization remain unknown, though TC-PTP C216S mutant, and not an S52A/C216S double mutant had the ability to trap a phosphorylated substrate of &sim;105kD

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7

Scalera, Giovanni Battista. "Risonanza Magnetica Dinamica e TC multifasica nella caratterizzazione dei tumori renali di piccole dimensioni (<3cm)." Doctoral thesis, Università di Catania, 2012. http://hdl.handle.net/10761/1112.

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Allo stato attuale RM dinamica e TC multifasica mediante l analisi dell enhancement consentono informazioni quali- quantitative della vascolarizzazione di piccoli tumori renali e quindi una più accurata caratterizzazione. TIPOLOGIA DELLO STUDIO ED OBIETTIVI Studio retrospettivo di piccole masse renali con diagnosi istologica, identificate con ecografia e/o con TC trifasica. OBIETTIVO PRIMARIO: Confrontare i risultati della RM dinamica e della TC trifasica nella valutazione quali- quantitativa dell enhacement dei carcinomi renali di piccole dimesioni. OBIETTIVO SECONDARIO: Valutare la po

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8

Karlsson, Susann. "T-Cell Protein Tyrosine Phosphatase, a Regulator of the PDGF Signaling Pathway." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-107674.

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9

Santos, Denise Takehana dos. "Mapeamento topográfico metabólico de carcinomas espinocelulares de cabeça e pescoço utilizando a fusão de imagens 18 F-FDG PET - TC." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/23/23139/tde-09082005-124541/.

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O objetivo desta pesquisa foi estabelecer uma metodologia para avaliar carcinomas espinocelulares (CEC) de cabeça e pescoço, identificando e distinguindo áreas de maior atividade metabólica dentro da neoplasia, associando dados simultaneamente adquiridos, obtidos por diferentes modalidades de aquisição de imagens, combinando informações metabólicas e anatômicas num único exame. A população estudada consistiu de 17 pacientes com carcinoma espinocelular (CEC) de cabeça e pescoço pertencentes aos arquivos do Departamento de Imagem do Hospital do Câncer, São Paulo. As imagens de TC (tomografia com

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10

Mestre, Torres Jaume. "Tesi doctoral: factors pronòstics en la pèrdua visual en l’arteritis de cèl·lules gegants." Doctoral thesis, Universitat Autònoma de Barcelona, 2019. http://hdl.handle.net/10803/669749.

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L’arteritis de cèl·lules gegants és la vasculitis més freqüent en persones majors de 50 anys. Es classifica segons els criteris de Hunder (1990), essent la cefalea el símptoma més freqüent. L’afectació vascular s’ha estudiat de forma extensa amb diferents proves d’imatge i amb la biòpsia de l’artèria temporal, havent-se suggerit que existeixen dos subtipus de la malaltia. Es coneix que una proporció elevada de pacients presenta aortitis i que aquesta s’associa a una major dosi acumulada de corticoides i a un major risc d’aneurisma d’aorta toràcica. Per altra banda, l’afectació ocular constitue

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11

Kirlangic, Ozgur Ulas. "Generation Of Surface Waves Due To Sudden Movements At The Sea Bottom." Master's thesis, METU, 2004. http://etd.lib.metu.edu.tr/upload/12604968/index.pdf.

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A mathematical model is developed for investigating time dependent surface deformations of a hydrostatic water volume, when it is subjected to a sudden partial collapse or rise of the sea bottom. The model solves two-dimensional Navier-Stokes Equations on a vertical plane numerically by using Marker and Cell Method (MAC) for viscous and compressible fluid including all the nonlinear effects in the solution. For demonstration, a vertical motion was given to a section in a hypothetical reservoir bed within a short time period and the resulting velocity and pressure fields and the surface profi

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12

Meredith, Isabella-Rose Sibly. "Mental health and asthma control during pregnancy: investigating underlying immune mechanisms." Thesis, 2015. http://hdl.handle.net/2440/111990.

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Background: Asthma during pregnancy has been associated with poor pregnancy outcomes such as pre-eclampsia, small for gestational age babies and preterm birth. Depression and anxiety are associated with reduced asthma control in non-pregnant individuals. This study investigated whether depression/anxiety in combination with pregnancies complicated by asthma has a negative effect on asthma control. Potential immune mechanisms that may drive worsening asthma were also investigated. Methods: One hundred and eighty-nine asthmatic women with and without depression/anxiety were followed throughout t

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13

Jang, Guo Shiang, and 張國祥. "Study the immune responses of both T lymphocytes and dendritic cells to a high-dose GM-CSF-secreting cell-based vaccine in murine TC-1 cancer model." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/18839765932401606662.

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碩士<br>長庚大學<br>生物醫學研究所<br>99<br>Cervical cancer is the second largest cause of cancer-related death in women Worldwide, which occurs following persistent infection with specific high-risk human papillomaviruses (HPV). Even though the prophylactic vaccines were approved and became available in the market in recent years. There also need therapeutic vaccines to combat high-risk HPV-associated cancers of those had been infected. In order to increase tumor antigen presentation of therapeutic vaccines, we previously modified wild-type GM-CSF gene (wtGM) into codon-optimized GM-CSF (cGM), and then us

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14

"Should glomerular filtration rate (GFR) be affected by the amount of viable, functioning tubular cells which in turn reflected by absolute renal uptake of Tc-99m DMSA." 1998. http://library.cuhk.edu.hk/record=b5889784.

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Wong Wai Lun.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 1998.<br>Includes bibliographical references (leaves 119-125).<br>Abstract also in Chinese.<br>Acknowledgments --- p.i<br>Legend for Figures --- p.ii<br>Legend for Tables --- p.iv<br>Abstract --- p.v<br>Abstract in Chinese --- p.ix<br>Chapter Chapter I --- Introduction --- p.1<br>Objective --- p.5<br>Chapter Chapter II --- Literature Review<br>Chapter II.1. --- Anatomy of the urinary system --- p.6<br>Chapter II.2. --- Physiology of the urinary system --- p.10<br>Chapter II.3. --- Methods for investigating the urinary

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15

Štěpánek, Ivan. "Imunoterapie nádorů asociovaných s virem HPV16 a regulace protinádorové imunitní odpovědi." Doctoral thesis, 2013. http://www.nusl.cz/ntk/nusl-322227.

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The MHC class I status of tumour cells during immunotherapy is often underestimated. It represents one of important tumour escape mechanisms and thus can contribute to the failure of most of the cancer clinical trials that are usually based on the induction of cytotoxic T cell responses. Epigenetic changes in the promoters of genes involved in the MHC class I Ag presentation can result in decreased expression of the cell surface MHC molecules on tumour cells. Thus, epigenetic modifiers can restore an expression of the MHC class I molecules and make tumours visible to the CD8+ effector cells. B

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16

Lopes, João Eduardo Casalta. "Characterization of multidrug resistance reversion in human colorectal adenocarcinoma cell lines." Master's thesis, 2010. http://hdl.handle.net/10316/18592.

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Introduction: Multidrug resistance (MDR) is a condition defined by the cross-resistance to several non-structurally related drugs, representing one of the major setbacks to the success of chemotherapy. One of the best studied MDR mechanisms is the overexpression of efflux pumps, such as P-glycoprotein (Pgp), multiple resistance-related protein 1 (MRP-1) and major vault protein (LRP). These proteins confer resistance to a large spectrum of similar substrates, despite their different extrusion mechanisms. Pharmacologic inhibition of MDR transporters is the major strategy to overcome this phenoty

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17

Chen, Yu Sing, and 陳郁欣. "Study of Immune Responses after Multiple Autologous Whole Cervical Tumor Cell Vaccination in TC-1 Mouse Model." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/24491702966089944693.

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碩士<br>長庚大學<br>生物醫學研究所<br>103<br>The antigens of tumor cells are highly similar to those in the normal host cells, suggesting that they are not easily recognized by the host immune system. Early research found that immunization with tumor cell based vaccines may effectively induce tumor antigen-specific T cell activation and proliferation. Granulocyte-macrophage colony-stimulating factor (GM-CSF) has been broadly used as adjuvant with DNA vaccines and tumor vaccines. Immunizations with codon-optimized GM-CSF plasmid DNA-vaccine result in an effective cytotoxic T lymphocyte response. Previous st

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18

Medapati, Manoj Reddy. "Extracellular S100A4 induces human thyroid cancer cell migration." 2013. http://hdl.handle.net/1993/22120.

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Human thyroid cancer is the most commonly occurring cancer of the endocrine gland having good survival rate, but some patients show recurrence with an invasive phenotype and treatment failures. The mechanisms behind this invasive phenotype are not well understood in TC. Previously our group has identified a pro-migratory role of relaxin-like peptides in thyroid cancer that is mediated by S100A4. We have observed in human TC cells that extracellular S100A4 induces migration and activates ERK1/2, JNK/SAPK and NFkB signaling pathways. Employing immunohistochemistry and immunofluorescence we have

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19

Tu, Chao Chin, and 凃朝欽. "The inhibitory effect of small interference RNA of Human papillomavirus type 16 E6/E7 oncogenes on transforming phenotypes of TC-1 tumor cell line." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/91887070505238158078.

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碩士<br>亞洲大學<br>生物科技學系碩士班<br>93<br>Human papillomaviruses (HPV) are a family of small DNA viruses that have been linked to a variety of human diseases. The high-risk types of HPV, including HPV-16 and HPV-18, have been implicated in the causation and malignant progression of human cervical cancer. The consistent expression of two viral genes, E6 and E7, are required for the establishment and maintenance of a fully transformed phenotype. Therefore, the E6 and E7 genes can be considered relevant targets for anti-cancer therapy. Recently, a powerful reverse genetic tool termed small interfering RNA

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