Relevant bibliographies by topics / TBK-1

Academic literature on the topic 'TBK-1'

Author: Grafiati
Published: 10 December 2022
Last updated: 29 January 2023

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Journal articles on the topic "TBK-1"

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Aldino, Fals, Makbul Muksar, and Erry Hidayanto. "Tingkat Berpikir Kreatif Matematis Siswa SD Bergaya Kognitif Field Independent dalam Menyelesaikan Soal Open Ended." Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan 6, no. 5 (May 24, 2021): 747. http://dx.doi.org/10.17977/jptpp.v6i5.14799.

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<div align="center"><table class="KisiTabel1" width="645" border="1" cellspacing="0" cellpadding="0"><tbody><tr><td valign="top" width="439"><p><strong>Abstract:</strong> Describing the level of creative thinking ability of elementary school students with field independent cognitive style in solving open ended questions is the goal of this study. The indicators used to observe the level of creative thinking ability, namely, fluency, flexibility, and originality are divided into five levels, but findings in the field there are only three levels, namely tbk1, tbk3, and tbk4. The subjects in this study were 3 grade vb students of sd islam mohamad hatta who had a field independent cognitive style with a classification of high, medium and low mathematical abilities. In this study, data were obtained by means of the group embedded figures test (geft), open-ended questions, and interviews. The results of this study indicate that the level of creative thinking that can be identified, namely fd students with high mathematical abilities meet the indicators of creative thinking aspects of fluency, flexibility and novelty so that they are included in the very creative category (tbk4), fd students with moderate mathematical abilities meet the indicators of creative thinking aspects of fluency and flexibility but does not meet the novelty aspect so that it is declared creative (tbk 3) and fd students with low math abilities are only able to meet the fluency aspect so they are declared less creative (tbk 1).</p><p><strong>Abstrak:</strong><strong> </strong>Mendeskripsikan tingkat kemampuan berpikir kreatif siswa SD yang bergaya kognitif field independent dalam menyelesaikan soal <em>open ended</em> merupakan tujuan dari penelitian ini. Indikator yang di gunakan untuk mengamati tingkat kemampuan berpikir kreatif, yaitu, <em>fluency </em>(kelancaran), <em>fleksibility</em> (keluwesan), dan <em>originality</em> (kebaruan) dibagi menjadi lima tingkatan, namun temuan di lapangan hanya terdapat tiga tingkatan yaitu TBK1, TBK3, dan TBK4. Subjek pada penelitian ini merupakan tiga siswa kelas Vb SD Islam Mohamaad Hatta yang memiliki gaya kognitif field independent dengan klasifikasi kemampuan matematika tinggi, sedang dan rendah. Pada penelitian ini data di peroleh dengan <em>Group Embedded Figures Test</em> (GEFT), tes soal <em>open ended</em>, serta wawancara. Hasil penelitian ini menunjukkan bahwa tingkat berpikir kreatif yang dapat diidentifikasi yaitu siswa FD berkemampuan matematika tinggi memenuhi indikator berpikir kreatif aspek kelancaran, keluwesan, dan kebaruan sehingga termasuk dalam kategori sangat kreatif (TBK4), siswa FD dengan kemampuan matematika sedang memenuhi indikator berpikir kreatif aspek kelancaran dan keluwesan namun tidak memenuhi aspek kebaruan sehingga dinyatakan kreatif (TBK 3) dan siswa FD berkemampuan matematika rendah hanya mampu memenuhi aspek kelancaran saja sehingga dinyatakan kurang kreatif (TBK 1).<strong></strong></p></td></tr></tbody></table></div>
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R, Adellara Mutya, Maiyastri Maiyastri, and Yudiantri Asdi. "PENENTUAN PORTOFOLIO DAN VALUE AT RISK MENGGUNAKAN MODEL ARMA-GARCH." Jurnal Matematika UNAND 8, no. 1 (July 5, 2019): 1. http://dx.doi.org/10.25077/jmu.8.1.1-8.2019.

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Dalam dunia investasi saham merupakan bentuk yang paling populer di kalangan masyarakat. Pada saham terdapat nilai risiko dan nilai ekspektasi return yang perlu dipertimbangkan oleh investor. Nilai Ekspektasi return dapat dihitung menggunakan model analisis deret waktu yaitu ARMA, sedangkan nilai risiko dapat diukur menggunakan beberapa metode salah satunya adalah metode Value at Risk (VaR). Untuk menghitung VaR diperlukan komponen volatilitas. Volatilitas dapat diestimasi menggunakan analisis deret waktu yaitu GARCH. Pada penelitian ini, peramalan dilakukan menggunakan data harga penutupan saham PT Astra Internasional Tbk, PT Bank Central Asia Tbk, PT Bank Negara Indonesia Tbk, PT Bank Rakyat Indonesia Tbk, dan PT Telekomunikasi Indonesia Tbk. Model terbaik yang didapatkan untuk mengestimasi nilai ekspektasi retrun diantaranya MA(1) untuk PT Astra Internasional Tbk, AR(1) untuk PT Bank Central Asia Tbk, ARMA(1,1) untuk PT Bank Rakyat Indonesia Tbk, MA(1) untuk PT Bank Rakyat Indonesia Tbk, dan MA(1) untuk PT Telekomunikasi Indonesia. Sedangkan model terbaik untuk mengestimasi nilai volatilitas adalah GARCH(1,1) untuk masing-masing perusahaan. Dengan menggunakan model ARMA-GARCH yang telah diestimasi diperoleh nilai VaR terbesar sampai terkecil secara berturut-turut terjadi pada saham PT Bank Negara Indonesia Tbk, PT Astra Internasional Tbk, PT Bank Rakyat Indonesia Tbk, PT Telekomunikasi Indonesia Tbk, dan PT Bank Central Asia Tbk. Bobot portofolio yang diperoleh adalah 5.47% untuk saham PT Astra Internasional Tbk, 44.52% untuk saham PT Bank Central Asia Tbk, 1.49% untuk saham PT Bank Negara Indonesia Tbk, 6.48% untuk saham PT Bank Rakyat Indonsia Tbk, dan 42.02% untuk saham PT Telekomunikasi Indonesia Tbk.Kata Kunci: VaR, Portofolio, ARMA, GARCH
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Purnomo, Risky Cahyo, S. Sunardi, and Titik Sugiarti. "Profil Kreativitas dalam Pemecahan Masalah Matematika Ditinjau dari Gaya Kognitif Field Independent (FI) dan Field Dependent (FD) Siswa Kelas VIII A SMP Negeri 12 Jember." Jurnal Edukasi 4, no. 2 (August 14, 2017): 9. http://dx.doi.org/10.19184/jukasi.v4i2.5203.

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Tujuan penelitian ini adalah untuk mendeskripsikan tingkat kreativitas dalam pemecahan masalah matematika. Penelitian ini termasuk jenis penelitian deskriptif dan menggunakan pendekatan kualitatif. Subjek penelitian sebanyak 7 siswa kelas VIII A SMP Negeri 12 Jember yang dikelompokkan berdasarkan gaya kognitif menggunakan instrumen Group Embedded Figures Test (GEFT), dengan rincian 4 siswa field independent dan 3 siswa field dependent. Metode pengumpulan data dalam penelitian ini adalah tes kemampuan berpikir kreatif dan wawancara. Penelitian ini menggunakan triangulasi waktu, yaitu dengan membandingkan data yang diperoleh dari tes kemampuan berpikir kreatif dan wawancara pertama dan tes kemampuan berpikir kreatif dan wawancara kedua. Hasil tes kemampuan berpikir kreatif melalui pemecahan masalah matematika dikelompokkan berdasarkan karakteristik berpikir kreatif, yaitu kelancaran, keluwesan, dan kerincian. Tingkat kreativitas atau disebut Tingkat Berpikir Kreatif (TBK) dikategorikan menjadi 5 tingkatan, yaitu TBK 4 (sangat kreatif), TBK 3 (kreatif), TBK 2 (cukup kreatif), TBK 1 (kurang kreatif), dan TBK 0 (tidak kreatif). Tingkat kreativitas yang dapat diidentifikasi dalam penelitian ini adalah 1 siswa field independent dinyatakan sangat kreatif (TBK 4) dan 3 siswa field independent dinyatakan kreatif (TBK 3). Untuk siswa field dependent, tingkat kreativitas yang dapat diidentifikasi adalah 1 siswa dinyatakan kreatif (TBK 3), 1 siswa dinyatakan cukup kreatif (TBK 2), dan 1 siswa dinyatakan kurang kreatif (TBK 1). Hasil ini menunjukkan bahwa siswa field independent cenderung lebih memiliki kreativitas dibanding siswa field dependent dalam pemecahan masalah matematika. Kata Kunci: berpikir kreatif, gaya kognitif field independent, gaya kognitif field dependent, pemechan masalah.
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Fauziah, Eka Wulandari, S. Sunardi, and Arika Indah Kristiana. "Analisis Tingkat Berpikir Kreatif Dalam Pengajuan Masalah Matematika Pokok Bahasan Bangun Ruang Sisi Datar Berdasarkan Gaya Kognitif Reflektif-Impulsif Siswa Kelas VIII-F SMP Negeri 12 Jember." Jurnal Edukasi 2, no. 2 (December 18, 2016): 1. http://dx.doi.org/10.19184/jukasi.v2i2.3502.

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Tujuan dari penelitian ini untuk mendeskripsikan tingkat berpikir kreatif dalam pengajuan masalah matematika. Penelitian ini merupakan jenis penelitian deskriptif. Subjek penelitian sebanyak 15 siswa kelas VIII-F SMP Negeri 12 Jember yang dipilih berdasarkan tes kognitif menggunakan instrumen Matching Familiar Figure Test (MFFT), dengan rincian 7 siswa reflektif dan 8 siswa impulsif. Metode pengumpulan data dalam penelitian ini adalah tes berpikir kreatif dan wawancara. Wawancara digunakan untuk memeriksa kembali jawaban siswa sekaligus sebagai triangulasi data. Dalam penelitian ini, berpikir kreatif siswa diukur menggunakan 3 kriteria berpikir kreatif, yaitu kefasihan, fleksibilitas, dan kebaruan. Tingkat berpikir kreatif atau disebut TBK dikategorikan menjadi 5 tingkatan, yaitu TBK 4 (sangat kreatif), TBK 3 (kreatif), TBK 2 (cukup kreatif), TBK 1 (kurang kreatif), dan TBK 0 (tidak kreatif). Hasil penelitian menunjukkan bahwa 3 siswa reflektif dinyatakan sangat kreatif (TBK 4) dan 4 siswa reflektif dinyatakan kreatif (TBK 3). Persentase tingkat berpikir kreatif untuk kelompok siswa reflektif adalah 42,86% siswa masuk dalam kategori TBK 4 dan 57,14% siswa masuk dalam kategori TBK 3. Untuk siswa impulsif, tingkat berpikir kreatif yang dapat diidentifikasi adalah 2 siswa dinyatakan kreatif (TBK 3), 3 siswa dinyatakan cukup kreatif (TBK 2), dan 3 siswa dinyatakan kurang kreatif (TBK 1). Persentase tingkat berpikir kreatif siswa impulsif tersebut berturut-turut adalah 25% siswa masuk dalam kategori TBK 3, 37,5% siswa masuk dalam kategori TBK 2 dan 37,5% siswa masuk dalam kategori TBK 1. Hasil tersebut menunjukkan bahwa siswa reflektif lebih memiliki kreativitas dibandingkan dengan siswa impulsif. Kata Kunci: Berpikir kreatif, gaya kognitif reflektif-impulsif, pengajuan masalah.
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Sinaga, Rina Melani, Ady Inrawan, Astuti Astuti, and Ruth Tridianty Sianipar. "PERBANDINGAN FINANCIAL DISTRESS PADA PT DUTA PERTIWI, Tbk DAN PT JAYA REAL PROPERTY, Tbk DENGAN MENGGUNAKAN METODE SPRINGATE." FINANCIAL: JURNAL AKUNTANSI 5, no. 2 (December 30, 2019): 70–79. http://dx.doi.org/10.37403/financial.v5i2.112.

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Tujuan penelitian ini adalah 1) Untuk mengetahui gambaran financial distress pada PT Duta Pertiwi, Tbk dan PT Jaya Real Property, Tbk. 2) Untuk mengetahui faktor yang menyebabkan perbedaan financial distress pada PT Duta Pertiwi, Tbk dan PT Jaya Real Property, Tbk. Penelitian ini merupakan penelitian deskriptif kualitatif. Financial Distress diukur dengan menggunakan Metode Springate. Hasil penelitian menunjukkan bahwa 1) PT Duta Pertiwi, Tbk diindikasi tidak bangkrut, sedangkan PT Jaya Real Property, Tbk diindikasi menghadapi ancaman kebangkrutan yang serius. 2) Faktor yang menyebabkan perbedaan financial distress PT Duta Pertiwi, Tbk dan PT Jaya Real Property, Tbk adalah nilai modal kerja bersih, peningkatan utang usaha pihak ketiga, penurunan kas dan setara kas, peningkatan beban usaha, serta efisiensi pengelolaan aset.Kata kunci: Financial Distress, Metode Springate.
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Dzahabiyya, Jauza, Dicky Jhoansyah, and R. Deni Muhammad Danial. "Analisis Nilai Perusahaan Dengan Model Rasio Tobin’s Q." JAD : Jurnal Riset Akuntansi & Keuangan Dewantara 3, no. 1 (April 19, 2020): 46–55. http://dx.doi.org/10.26533/jad.v3i1.520.

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Penelitian ini bertujuan untuk mengetahui nilai perusahaan pada PT.Indosat Tbk, PT.Telekomunikasi Indonesia Tbk dan PT. Smartfren Telcom Tbk periode 2016 - 2018 dengan memperhitungkan pengelolaan aset yang dimiliki perusahaan. metode yang digunakan dalam penelitian ini adalah deskriptif dengan pendekatan kuantitatif. Teknik analisis data yang digunakan dalam penelitian ini menggunakan rasio nilai perusahaan Tobin’s Q. Hasil penelitian menunjukan pada PT.Indosat Tbk periode 2016 – 2017 nilai Q > 1 artinya pengelolaan aset padaperusahaan berhasil dan saham overvalued sedangkan periode 2018 nilai Q < 1 artinya pengelolaan aset gagal dan saham undervalued. Pada PT.Telekomunikasi Indonesia Tbk periode 2016 – 2018 nilai Q > 1 artinya pengelolaan aset berhasil dan sahan overvalued. Pada PT Smartfren Telcom Tbk periode 2016 – 2018 nilai Q < 1 artinya pengelolaan aset gagal dan saham undervalued. Diantara perusahaan tersebut yang memiliki nilai Q paling baik adalah PT.Telekomunikasi Indonesia Tbk. Nilai Q dalam kondisi overvalued artinya perusahaan memiliki nilai perusahaan yang baik.
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Febriyanti, Ulfa Amalia, H. Hobri, and Susi Setiawani. "Tingkat Berpikir Kreatif Siswa Kelas VII dalam Menyelesaikan Soal Open-Ended Pada Sub Pokok Bahasan Persegi Panjang dan Persegi." Jurnal Edukasi 3, no. 2 (July 1, 2016): 5. http://dx.doi.org/10.19184/jukasi.v3i2.3521.

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Penelitian ini berhubungan dengan Tingkat Berpikir Kreatif Siswa Kelas VII dalam Menyelesaikan Soal Open-Ended Pada Sub Pokok Bahasan Persegi Panjang dan Persegi. Tujuan penelitian ini adalah untuk mengetahui kemampuan berpikir kreatif siswa dengan tingkat berpikir kreatif dalam menyelesaikan soal open-ended. Tingkat berpikir kreatif siswa ditentukan dari komponen kreativitas yang mampu dipenuhi siswa, yaitu kefasihan (fluency), keluwesan (fleksibility), dan kebaruan (originality). Pengklasifikasian tingkatannya ada 5 yakni, Tingkat Berpikir Kreatif 0 (TBK 0), Tingkat Berpikir Kreatif 1 (TBK 1), Tingkat Berpikir Kreatif 2 (TBK 2), Tingkat Berpikir Kreatif 3 (TBK 3) dan Tingkat Berpikir Kreatif 4 (TBK 4). Instrumen pengumpulan data yang digunakan adalah paket tes soal open-ended. Penelitian dilakukan di kelas VII C SMPN 7 Jember. Berdasarkan analisa data yang dilakukan dari hasil penelitian menunjukkan bahwa siswa TBK 1, TBK 2, TBK 3 dan TBK 4 masing-masing menunjukkan indikator berpikir kreatif yang dikaitkan dengan karakteristik berpikir kreatif seperti yang dikemukakan oleh Munandar, yaitu kefasihan, keluwesan, dan kebaruan. Terkecuali siswa dengan TBK 0 tidak menunjukkan ketiga indikator berpikir kreatif tersebut. Kata Kunci: tingkat berpikir kreatif, soal open-ended, persegi panjang dan persegi.
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Astria Semaradilla Syari. "EVALUASI KONDISI SAHAM MELALUI ANALISIS FUNDAMENTAL DENGAN METODE DIVIDEND DISCOUNT MODEL (DDM) TERHADAP KEPUTUSAN INVESTASI PADA PERUSAHAAN SUB SEKTOR PULP AND PAPER YANG TERDAFTAR DI BEI PERIODE 2011-2015." Jurnal Ekonomi STIEP 3, no. 2 (November 27, 2018): 1–13. http://dx.doi.org/10.54526/jes.v3i2.2.

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The purpose of this study was to: (1) determine the condition of stocks through fundamental analysis by the DDM on the company's pulp and paper subsectors period 2011-2015; (2) determine the company's investment decisions pulp and paper subsectors period 2011-2015. The results of this study indicate that (1) the highest intrinsic value is at PT Fajar Surya Wisesa Tbk which is equal to 924.7226 and the lowest intrinsic value is at Paper Factory PT Tjiwi Kimia Tbk, which amounted -1,787,541; (2) The company PT kedawung Setia Industrial Tbk in the period 2011-2015 has a condition undervalued stocks. Meanwhile, other companies namely PT Alkindo Naratama Tbk, PT Fajar Surya Wisesa Tbk, PT Indah Kiat Pulp & Paper Tbk, PT Suparma Tbk, and PT Pabrik Kertas Tjiwi Kimia Tbk experienced overvalued.
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Syahputra, Doni, Herlina Helmy, and Erly Mulyani. "Analisis Pengungkapan Lingkungan Berdasarkan Global Reporting Initiatives (Gri) G4." JURNAL EKSPLORASI AKUNTANSI 1, no. 2 (June 10, 2019): 678–93. http://dx.doi.org/10.24036/jea.v1i2.102.

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This study aims to analyze: 1) The level of environmental disclosure of PT Bukit Asam (Persero), Tbk. and PT Indo Tambangraya Megah, T;bk. for the year 2016-2017 based on the GRI G4 Guideliness, 2) The breadth and depth of environmental disclosure of PT Bukit Asam (Persero), Tbk. and PT Indo Tambangraya Megah, Tbk. for the year 2016-2017. This is a descriptive qualitative research using two mining companies, namely, PT Bukit Asam (Persero), Tbk. and PT Indo Tambangraya Megah, Tbk. Data for this study were secondary from annual report and sustainability report were analysed using content analysis technique. The results show that: 1) the level of disclosure on economic, social and environmental performance indicators is higher for PT Aneka Tambang, Tbk. compared to those of PT Vale Indonesia, Tbk. 2) the breadth and depth of sustainability report disclosure of PT Indo Tambangraya Megah, Tbk, is better compared to those of PT Bukit Asam (Persero), Tbk.
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Early Armein and Diah Aryati Prihartini. "Analysis Of Implementation Of Psak No. 1 Concerning Presentation Of Financial Statements At Pt Siantar Top Tbk." International Journal of Science, Technology & Management 2, no. 6 (November 27, 2021): 2267–73. http://dx.doi.org/10.46729/ijstm.v2i6.407.

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Purpose of this research in scientific writing is to find out whether PT Siantar Top Tbk has implemented its financial statements in accordance with PSAK no. 1. The data used by the author in this study are secondary data from the financial statements of PT Siantar Top Tbk in 2019 by downloading from the site www.idx.co.idwebsite. The data analysis method used in scientific writing is descriptive-comparative method. In this method the authors analyze and compare the financial statements of PT Siantar Top Tbk with PSAK No. 1. The results of this study show that there are still items that are not listed in the 2019 financial statements of PT Siantar Top Tbk. However, most of the 2019 financial statements of PT Siantar Top Tbk have implemented their financial statements in accordance with PSAK No. 1. Therefore, the implementation of the presentation of financial statements at PT Siantar Top Tbk must continue to be adjusted to PSAK No. 1. It is useful to be able to present complete financial statements in accordance with PSAK No. 1.
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Dissertations / Theses on the topic "TBK-1"

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Stephan, Heike Isabell [Verfasser], Ellen [Akademischer Betreuer] Niederberger, and Bernhard [Akademischer Betreuer] Brüne. "Untersuchungen zur Rolle der TANK-Binding Kinase (TBK) 1 bei entzündlichen Schmerzreaktionen / Heike Isabell Stephan. Gutachter: Ellen Niederberger ; Bernhard Brüne." Frankfurt am Main : Univ.-Bibliothek Frankfurt am Main, 2015. http://d-nb.info/1070911038/34.

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Stephan, Heike [Verfasser], Ellen [Akademischer Betreuer] Niederberger, and Bernhard [Akademischer Betreuer] Brüne. "Untersuchungen zur Rolle der TANK-Binding Kinase (TBK) 1 bei entzündlichen Schmerzreaktionen / Heike Isabell Stephan. Gutachter: Ellen Niederberger ; Bernhard Brüne." Frankfurt am Main : Univ.-Bibliothek Frankfurt am Main, 2015. http://d-nb.info/1070911038/34.

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Harris, Jennifer. "Regulation of nuclear factor kappa B subunit c-Rel through phosphorylation by two IKK-related kinases, IKK epsilon and TBK-1." Thesis, McGill University, 2005. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=82250.

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The nuclear factor kappaB (NF-kappaB) transcription factors are key regulators of immunomodulatory genes regulation. NF-kappaB activity is regulated through the phosphorylation of inhibitory proteins (IkappaBs) by the IkappaB kinase (IKK) complex (IKK alpha/beta/gamma), leading to IkappaB degradation and NF-kappaB translocation to the nucleus where they promote transcription of immunoregulatory genes. Moreover, cRel and p65 activities are also regulated by direct phosphorylation of their transactivation domain. Recently, two IKK non-canonical homologues, IKKepsilon and TBK-1 (TANK binding kinase-1) have been identified with functions distinct from the classical IKKalpha/IKKbeta. TBK-1/IKKepsilon trigger antiviral immunity through direct phosphorylation of the IRF3/IRF7 transcription factors, which are key regulators of the interferon response. Since IKKepsilon modulates the activity of IRF3/IRF7, it is of interest to assess whether IKKepsilon/TBK-1 also regulates the transactivation activity of NF-kappaB. Our hypothesis was that IKKepsilon/TBK-1 modulates the activity of cRel by direct phosphorylation of its transactivation domain (TD). In this study, we demonstrate that IKKepsilon and TBK-1 directly phosphorylate cRel in vitro and in vivo. Two of the three consensus sequences recognized by IKKepsilon/TBK-1 in the cRel TD are directly phosphorylated by IKKepsilon. cRel was translocated to the nucleus in cells expressing wild type versus kinase dead variant. The expression of IKKepsilon increases c-Rel transactivation in reporter gene assays. Serine to alanine mutation was further used to characterize the function of this phosphorylation at the level of nuclear translocation and transactivation potential using immunofluorescence and reporter gene assay. Furthermore, co-expression studies revealed that IKKepsilon and not the kinase dead variant is responsible for cRel degradation in a dose-dependent manner and this effect is partially revert
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Lack, Jeremy David. "The solution structure and surface properties of TB3 of LTBP-1." Thesis, University of Oxford, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249190.

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Elizondo, Juan Iraburu. "Medição de Densidade no Tokamak TBR-1 por Rotação de Faraday." Universidade de São Paulo, 1996. http://www.teses.usp.br/teses/disponiveis/43/43131/tde-02072013-115509/.

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Neste trabalho, são apresentados os resultados experimentais de medições de densidade eletrônica no tokamak TBR-l, obtidas por meio de rotação de Faraday num feixe de micro-ondas. O feixe (65 GHz, 500 m W) é gerado por uma klystron e atravessa o plasma no plano médio horizontal. Os valores obtidos para a densidade concordam bem com as medições feitas com um interferômetro de micro-onda o; convencional. A partir das simulações numéricas e das medições, conclui-se ser recomendável o uso de comprimentos de onda menores, para minimizar a refração do feixe no plasma, Os resultados obtidos demonstram a viabilidade do método de medição de densidade por rotação de Faraday. em experiência feita pela primeira vez em tokamak, para a geometria considerada.
In this work, the experimental results of electronic density measurements in the TBR-l tokamak, obtained by Faraday rotation of a microwave beam, are presented. The beam (65 GHz, 500 mW) is generated by a klystron and crosses the plasma in the horizontal plane. The density values obtained are in agreement with the measurements of a conventional microwave interferometer. As a result of numerical simulations and measurements, it can be concluded that it would be advisable the use of lower wavelengths, to minimize the beam refraction when it crosses the plasma. The results show the feasability of the Faraday rotation method for density measurement, in the first experiment performed in a tokamak for the geometry considered.
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Littlejohn, Erica Latrice. "INSULIN-LIKE GROWTH FACTOR-1 OVEREXPRESSION MEDIATES HIPPOCAMPAL REMODELING AND PLASTICITY FOLLOWING TBI." UKnowledge, 2018. https://uknowledge.uky.edu/physiology_etds/39.

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Every year over 2.5 million traumatic brain injuries (TBI) occur and are the leading cause of death and disability among adolescents. There are no approved treatments for TBI. Survivors suffer from persistent cognitive impairment due to posttraumatic tissue damage and disruption of neural networks which significantly detract from their quality of life. Posttraumatic cognitive impairment depends in part on the brain's limited ability to repair or replace damaged cells. Immature neurons in the hippocampus dentate gyrus, a brain region required for learning and memory, are particularly vulnerable to TBI. Insulin-like growth factor-1 (IGF1) is a potential therapeutic for TBI because it is a potent neurotrophic factor capable of mediating neuroprotection, neuro-repair, and neurogenesis. We hypothesized that conditional IGF1 overexpression in the mouse hippocampus following experimental controlled cortical impact injury (CCI) would enhance posttraumatic neurogenesis chronically. To this end, conditional astrocyte-specific IGF1 overexpressing mice (IGFtg) and wild-type (WT) mice received CCI or sham injury. The proliferation marker BrdU was used to label neurons born the first week after injury. Six weeks after injury, when surviving posttrauma-born neurons would be fully developed, we counted proliferated cells (BrdU+) and the subset expressing a mature neuronal marker (NeuN+/BrdU+) in the hippocampus. We also assessed cognitive performance during radial arm water-maze reversal (RAWM-R) testing, a neurogenesis-sensitive assay. IGF1 promoted end-stage maturity and decreased mis-migration of neurons born after trauma. These effects coincide with IGF1 induced improvements in performance on neurogenesis sensitive cognition following TBI. Mammalian target of rapamycin (mTOR), an early signaling molecule downstream of IGF1, has been identified as a potential target for TBI interventions because of its regulatory role in neuronal plasticity and neurogenesis. However, recent studies have also reported maladaptive plasticity and recovery associated with posttraumatic mTOR activation. It is imperative to elucidate the mechanism of action of IGF1 during pre-clinical evaluations. We hypothesized that IGF1 mediates posttraumatic neurogenic effects through IGF1 induction of mTOR activation. We injured cohorts of IGFtg and WT mice and harvested their brains for immunohistochemistry to assess IGF1 overexpression effects on posttraumatic mTOR activation at 1, 3, and 10 days post-injury (dpi). We found that IGF1 upregulated mTOR activation following TBI in a region-specific manner at 1 and 3dpi. To determine if IGF1 regulated differentiation and arborization through the mTOR pathway, injured WT and IGFtg mice received daily i.p. injections of rapamycin (10mg/kg), the inhibitor of mTOR, or its vehicle for 7 days. Vehicle and rapamycin administration began 3dpi, after the cells dividing at the peak of posttraumatic proliferation were labeled with BrdU. IGF1 enhancement of posttraumatic neurogenesis was not dependent on mTOR activation. In summary, IGF1 directs newborn neuron localization, promotes end-stage maturation, and chronically improves cognition. IGF1 can stimulate posttraumatic neurogenesis and plasticity independent of mTOR activation. These data suggest that IGF1 can stimulate neuron replacement following trauma-induced hippocampal neuron loss and cognitive improvement. Further studies should investigate IGF1 and mTOR inhibition as a combination therapy for neurorehabilitation.
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Russell, Nicholas H. "Heme Oxygenase 1 expression after traumatic brain injury and effect of pharmacological manipulation on functional recovery." VCU Scholars Compass, 2017. https://scholarscompass.vcu.edu/etd/5525.

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Traumatic Brain Injury (TBI) is an increasingly diagnosed constellation of injuries derived from acute mechanical trauma to the brain. With the rise of advanced neuroimaging techniques recent focus has oriented primarily towards the mild-moderate range of TBI which previously was missed diagnostically. Characteristically, these advances have shown increasing areas of micro-hemorrhage in susceptible areas of the brain and to date there are no treatment modalities targeting micro-hemorrhages or their sequelae. This dissertation explores the effects of the resulting heme processing response in the days following injury with a particular focus on inducing early heme clearance from the parenchyma using a rat central fluid percussion injury model in the mild-moderate injury range. Since heme is released ~24-48 hours post-injury and is known to be cytotoxic we observed there may be a critical window for treatment to clear heme before it is spontaneously released and to increase the buffering capacity of the tissue. We targeted heme clearance by using drugs known to increased expression of Nrf2, an upstream transcriptional regulator of the canonical heme processing protein heme oxygenase 1 (HO-1), and tracking expression of HO-1, the iron sequestration/storage proteins Lipocalin 2 (LCN2) and Ferritin (FTL), as well as the activity of matrix metalloproteinases 2 and 9 (MMP2, MMP9). We examined both tissue known to be frankly hemorrhagic (the neocortex) as well as tissue lacking any identifiable bleed (the hippocampus). We demonstrated that using the HO-1 inducers Hemin and Sulforaphane in a single dose paradigm given 1 hour post-injury heme clearance was accelerated in the neocortex with the majority of heme pigment processed by 24 hours post-injury. Further there was significant attenuation of protein expression in HO-1 and ferritin as well as the enzyme activity of MMP2 and MMP9 in both the neocortex and the hippocampus. Behavioral attenuation was also seen in both rotarod and Morris water maze tests. While we intended to target hemorrhagic processing after injury, and indeed demonstrated improved clearance of heme from post-injury hemorrhagic regions of the brain, in both tissues studied we observed remarkably similar responses to the drugs utilized in protein expression, enzyme activity, and behavioral improvement which may suggest a globally improved pathologic state or that there are unidentified pathologic micro-hemorrhages or leaky vessels which extend further into the brain parenchyma than currently identified.
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Yuan, Xuemei. "NMR studies of a TB module from human fibrillin-1." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.298231.

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Silva, Ruy Pepe da. "Transporte de partículas e energia no plasma do tokamak TBR-1: diagnósticos e estudo experimental." Universidade de São Paulo, 1989. http://www.teses.usp.br/teses/disponiveis/43/43131/tde-16122013-153129/.

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Os estudos sobre o plasma na região da borda de máquinas tokamak têm se intensificado nos últimos anos em decorrência da constatação de que o comportamento do plasma na região central da máquina é bastante influenciado por processos que ocorrem na borda da coluna. Neste trabalho feito um estudo experimental das propriedades de transporte do plasma na região da sombra do limitador do TBR-l, um tokamak de pequeno porte em operação no Instituto de Física da Universidade de São Paulo. São também determinados os tempos de confinamento globais de partículas e energia. Três foram os diagnósticos usados neste trabalho. Inicialmente, é abordada a utilização de sondas de Langmuir para a obtenção de perfis radiais e temporais da temperatura de elétrons, densidade e potencial de plasma; descreve-se também o arranjo experimental usado para este diagnóstico. A seguir, discute-se o projeto e a construção de uma sonda sensível a íons associada a um sistema eletrônico que permitiu a determinação simultânea das temperaturas locais de íons e elétrons. Finalmente, é discutido o dimensionamento e a implantação de um interferômetro de microondas para medidas de densidade de elétrons na região central da coluna de plasma do TBR-1; o sistema opera em 65 GHz e toda a eletrônica associada foi projetada e construída em nosso Laboratório. Os resultados obtidos com as sondas foram analisados com o ajuda de um modelo não colisional de transporte de partículas e energia para a região da sombra do limitador de máquinas tokamak. A partir dos decaimentos radiais da termperatura de elétrons (\'lâmbda IND. e\' \'APROXIMADAMENTE IGUAL A\' 2,6cm) e da densidade (\'lâmbda IND. n\' \'APROXIMADAMENTE IGUAL A\' 1,4cm), bem como do fator de transmissão de energia para os elétrons (\'delta IND. e\' \'APROXIMADAMENTE IGUAL A\' 4), determinou-se o coeficiente de difusão perpendicular ao campo magnético (\'D IND. 1\' \'APROXIMADAMENTE IGUAL A\' 6 \'m POT. 2\'\'s POT. -1\') e a difusividade térmica dos elétrons (\'qui POT. e IND. 1\' \'APROXIMADAMENTE IGUAL A\' 8 \'m POT. 2\'\'s POT. -1\'), resultados que indicam valores próximos aos previstos pelo modelo de Bohm. As medidas das temperaturas de íons e elétrons mostram um claro desacoplamento térmico entre íons e elétrons (\'T IND. i\'/\'T IND. e\' \'APROXIMADAMENTE IGUAL A\' 2). As medidas de densidade obtidas no centro da coluna, em conjunto com as obtidas na borda, permitiram a determinação dos tempos de confinamento globais de partículas (\'tau IND. p\'\'APROXIMADAMENTE IGUAL A\' 1,8 x \'10 POT. -3\'s) e de energia (\'tau IND. E\'\'APROXIMADAMENTE IGUAL A\' 1,2 x \'10 POT. -4\'s). Os resultados foram comparados com os previstos por várias leis de escala.
The study of the plasma edge in Tokamak machines has increased in recent last years, since the recognition that the behavior of the plasma core is influenced by the Physical processes that occur in the edge region. This work develops an experimental stud) of plasma transport properties in the shadow region of TBR-l limiter. TBR-l is a small Tokamak in operation in the Physics Institute of São Paulo University. We have also determined the global confinement time of particles and energy. We have used three diagnostics: a Langmuir probe, an ion sensitive probe, and a microwave interferometer. Initially we discuss the use of Langmuir probes in Tokamak machines to obtain temporal and radial profiles of electron temperature, plasma density and potential; we show also the experimental arrangement used in the TBR-l for this diagnostic. Then, we discuss the design and construction of an ion sensitive probe associated with an electronic system, that was used to obtain, simultaneously, local ion and electron temperature. Finally we discuss a microwave interferometry system that has been built for the TBR-1. The microwave generator is a reflex Klystron (f = 65 GHz), and with the interferometer we obtained electron density time profiles of the center of TBR-l plasma column. All the electronics associated with the interferometer were designed and built in our laboratory. The results obtained with the probes are discussed with the help of a collisionless model for Tokamak scrape-off plasma. With the radial e-foldings of electron temperature (e 2.6 cm) and density (n 1.4 cm), and the sheath electron transmission coefficient (e 4) we have determined the cross-field diffusion coefficient (D1 6 m2s-1) and the electron cross-field thermal diffusivity (e1 8 m2s-1). These results indicate values near those predicted by the Bohm model. The measurements of electron and ion temperature shows a clear thermal decoupling between ions and electrons (T1/Te 2). The measurements of plasma parameters in the center of the plasma column, with that obtained with the probes permitted the determination of the particle (p 1.8 x 10-3s) and energy (e 1.2 x10-4s) global confinement times. These results were compared with those predicted by scaling laws.
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Neto, Ibrahim El Chamaa. "Estudo do Funcionamento do Tokamak TBR-1 sob a Influência de Perturbações Elétricas e Magnéticas." Universidade de São Paulo, 1998. http://www.teses.usp.br/teses/disponiveis/43/43131/tde-27022014-144055/.

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Neste trabalho foram realizados estudos experimentais de operação do tokamak TBR-I sob condições extremas de densidade e de campo magnético toroidal e, também, sob a influência de perturbações elétricas radiais e magnéticas helicoidais aplicadas na região periférica da coluna de plasma. Realizou-se, também, uma análise preliminar das características das descargas na região da corrente de plasma com predominância de elétrons fugitivos. Para isso foi utilizada a maioria dos diagnósticos já construídos no Laboratório de Física de Plasmas da USP, que são: diagnóstico por sondas eletrostáticas, bobinas de Mirnov, espectroscopia óptica, interferômetro de micro ondas, detector de raios-X duros, detector de H, bobinas de Rogowski, bobinas de posição, espiras das tensões de enlace e medição da pressão com \"ion-gauges\" e analisador de gás residual. Os resultados permitiram obter uma lei de escala para as descargas do TBR-1 associando a densidade média de partículas com a densidade média de corrente de plasma. Foram observados efeitos muito interessantes nas oscilações magnéticas do plasma sob ação dos campos perturbativos. Em particular, para os campos elétricos radiais com polarização negativa, observou-se uma diminuição considerável das frequências dessas oscilações e uma atenuação nas amplitudes das mesmas, segundo uma análise de Fourier. Ao contrário, para polarizações positivas, foi observado um plasma mais turbulento. Este resultado repetiu-se (porém não tão acentuado como descrito no caso anterior) quando foi aplicada uma perturbação magnética helicoidal simultaneamente com o campo elétrico radial. Finalmente, as descargas do TBR-1 são caracterizadas pela baixa densidade de elétrons n IND.e 10 POT.12 cm POT.-3 e alta corrente de elétrons fugitivos (I I IND.P). O parâmetro de Shafranov foi calculado a partir das medidas do campo magnético vertical e do deslocamento do centro da coluna de plasma. A diferença de A nos cálculos é explicada pelo deslocamento da órbita do feixe de elétrons fugitivos.
In this work, experimental studies of operation limits of the TBR-l tokamak were accomplished under extreme conditions of density and toroidal magnetic field, a1so, under the influences of helical magnetic field and radial electric field perturbations, applied in the border zone of the plasma column. Also, a preliminary analysis of the charactetistics of the runaway discharges was performed. For measurements of the plasma charactetistics most of the diagnostics built in the USP Laboratório de Física de Plasmas, were used: electrostatic probes, Mirnov coils, optical spectroscopy, micro wave interferometer, hard X-rays detector, H detector, Rogowski coils, position sensors, loop voltage, pressure measurements with ion-gauges and a residual gas analyzer. From the result, the scaling law for the discharges of the TBR-l were obtained, associating the average densities of particles with average plasma current densities. Very interesting effects were observed in the magnetic oscillations of the plasma under the action of the perturbation fields. In particular, for the radial electric fields with negative polarization a considerable decrease in the frequency and an attenuation in the amplitude of the MHD oscillations were observed, according to a Fourier analysis. On the contrary, for positive polarization a more turbulent plasma was observed. Similar results, but not so strong, were obtained when a helical magnetic perturbation was applied simultaneously with the radial electric field. Finally, runaway discharges in the TBR-l were investigated and the current was found to be predominantly dominated by e1ectron beams. The Shafranov parameter A was calculated from the vertical field as well as from the plasma center displacement and found to be different, which can he explained by the orbit shifted runaway beams.
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Books on the topic "TBK-1"

1

Indonesia) Seminar Nasional Efisiensi Energi untuk Peningkatan Daya Saing Industri Manufaktur & Otomotif Nasional (2nd 2011 Jakarta. Prosiding Seminar Nasional Efisiensi Energi untuk Peningkatan Daya Saing Industri Manufaktur & Otomotif Nasional (SNEEMO) 2011: William Soeryadjaya Hall, PT Astra International Tbk., 1 Oktober 2011. Edited by Agus Lukman editor. Jakarta: Politeknik Manufaktur Astra, 2011.

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Maslov, M. S. Ti︠a︡zhelyĭ bombardirovshchik TB-1. Moskva: T︠S︡eĭkhgauz, 2008.

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Maslov, M. S. Ti︠a︡zhelyĭ bombardirovshchik TB-1. Moskva: T︠S︡eĭkhgauz, 2008.

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Maslov, M. S. Ti︠a︡zhelyĭ bombardirovshchik TB-1. Moskva: T︠S︡eĭkhgauz, 2008.

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Boost ! Speaking Level 1 Tbk. Pearson Education, Limited, 2007.

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Haines, S. Gateway: Gateway 1 TBk Santillana HAINES. Santillana, S.A., 1996.

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Adamson, D. Touchdown: Touchdown 1 for Mexico TBk. Addison Wesley Longman ELT Division (a Pearson Education company), 1994.

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Dallas, Don. New Let's Learn English Tbk 1. Pearson Education, Limited, 2005.

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TBD Report 1. American Society for Training & Development, 2021.

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TBD Report 1. American Society for Training & Development, 2021.

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Book chapters on the topic "TBK-1"

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Marion, James. "TANK-Binding Kinase 1 (TBK1): Structure, Function, and Regulation." In Molecular Life Sciences, 1–9. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-6436-5_374-1.

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Marion, James. "TANK-Binding Kinase 1 (TBK1): Structure, Function, and Regulation." In Molecular Life Sciences, 1155–63. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4614-1531-2_374.

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Han, Guchang, Viloane Ko, Zaibing Guo, and Hao Meng. "Read Sensors for Greater than 1 Tb/In2." In Developments in Data Storage, 127–43. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2011. http://dx.doi.org/10.1002/9781118096833.ch7.

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Labuschagné, Antoinette, and Muazzam Jacobs. "HIV-1 and TB: How Humanized Mice Can Help." In Humanized Mice for HIV Research, 481–92. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1655-9_38.

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Wallace, Tracey D., and John T. Morris. "SwapMyMood: User-Centered Design and Development of a Mobile App to Support Executive Function." In Lecture Notes in Computer Science, 259–65. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-58805-2_31.

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AbstractThis paper describes the research and development of the SwapMyMood smartphone application designed to support use of evidence-based executive function strategies by people with traumatic brain injury. Executive dysfunction is a common sequela of traumatic brain injury (TBI) resulting in diminished cognitive-behavioral functioning. Problem-solving and emotion regulation are cognitive-behavioral functions that are often disrupted by changes in the executive control system. SwapMyMood is an electronic version of the Executive Plus/STEP program, a set of clinical techniques taught to people living with brain injury to help them 1) identify and implement solutions to problems encountered in daily life and 2) to utilize the emotion cycle to understand and regulate emotional responses to these problems. The Executive Plus/STEP program has until now relied on paper-based instruction and use. Input from target users – people with brain injury and clinical professionals who teach this program to their patients – has contributed to key refinements of features and functioning of the mobile app. Data gathered from target user participation in the user-centered design process are presented. Future directions for ongoing development of technologies to support executive function strategies are also discussed.
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Kwon, Oh Yeoul, Jong Chul Kim, Young Dong Kwon, Dae Jin Yang, Se Hoon Lee, and Zin Hyoung Lee. "Magnetostrictive Properties of TbxDy1-xFey(x=0.3, 0.33; y=1.05, 1.36, 1.65) Composite Made by Directional Solidification and Polymer Infiltration." In Materials Science Forum, 2247–50. Stafa: Trans Tech Publications Ltd., 2005. http://dx.doi.org/10.4028/0-87849-960-1.2247.

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Yang, Xin Xin, Y. M. Lu, S. K. Zhou, S. Y. Mao, J. X. Mi, Z. Y. Man, and J. T. Zhao. "RCu1+xSb2 (R = La, Ce, Pr, Nd, Sm, Gd, Tb, Dy, Ho and Y) Phases with Defect CaBe2Ge2-Type Structure." In Materials Science Forum, 861–64. Stafa: Trans Tech Publications Ltd., 2005. http://dx.doi.org/10.4028/0-87849-960-1.861.

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"TBP-Related Factor 1." In Encyclopedia of Systems Biology, 2146. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-9863-7_101455.

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J.D. Allen, Kenneth. "Suicide Following Traumatic Brain Injury: Pathogenesis and Neurocognitive Mechanisms." In Suicide [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.99259.

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Traumatic brain injury (TBI) is associated with varied neuropsychiatric sequelae, including elevated risk for later suicidal behaviors (SBs). This chapter provides a qualitative narrative review of hypothesized biological and neurocognitive mechanisms linking TBI to subsequent SBs. The following selective review specifically highlights: (1) Structural and functional alterations to neural circuitry secondary to common head injuries (e.g., concussions or mild TBI) as well as severe or repetitive TBI (e.g., chronic traumatic encephalopathy); (2) Overlap between post-TBI neuropsychological deficits and proposed bio-behavioral indicators of suicide risk; and (3) Potential neurocognitive mediators of the relationship between TBI and SBs, with a particular focus on executive functions involved in self-regulation (i.e., cognitive and affective inhibitory control) and their neural substrates, e.g., corticolimbic, frontostriatal, and frontoparietal circuitry. The chapter concludes with theoretical and practical implications of this shared pathophysiology, based on the reviewed empirical literature.
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Dye, Christopher. "Concepts and Models." In The Population Biology of Tuberculosis. Princeton University Press, 2015. http://dx.doi.org/10.23943/princeton/9780691154626.003.0002.

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This chapter discusses the epidemiology of tuberculosis from the perspective of population biology. The central concept of population biology with reference to TB control is that a population of organisms (here TB cases) cannot persist if the generation case reproduction number, R, is maintained below the critical value of one. Hence, if one case of TB always generates less than one secondary case on average (R < 1), then Mycobacterium tuberculosis is doomed to extinction. The chapter first provides an overview of the empirical epidemiology of TB before introducing a family of dynamic models to investigate the key questions about TB epidemiology and control. The models are used to assess TB transmission, reinfection and relapse, variation in infectiousness, rise and fall of TB during the industrial revolution, and the characteristics of TB epidemics.
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Conference papers on the topic "TBK-1"

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"TB6: materials 1." In Proceedings of the 21st IEEE Instrumentation and Measurement Technology Conference. IEEE, 2004. http://dx.doi.org/10.1109/imtc.2004.1351009.

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"TB1: chemical measurements 1." In Proceedings of the 21st IEEE Instrumentation and Measurement Technology Conference. IEEE, 2004. http://dx.doi.org/10.1109/imtc.2004.1350982.

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"TB2: signal processing 1." In Proceedings of the 21st IEEE Instrumentation and Measurement Technology Conference. IEEE, 2004. http://dx.doi.org/10.1109/imtc.2004.1350987.

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WIDAYATI, QORIANI, and RAHAYU AMALIA. "Call Drop Rate on Cellular Network Case Study of PT Indosat Tbk Palembang." In Eighth International Conference On Advances in Computing, Electronics and Electrical Technology - CEET 2018. Institute of Research Engineers and Doctors, 2018. http://dx.doi.org/10.15224/978-1-63248-144-3-27.

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Toklu, Y. Cengiz, Nurcan Çalış Açıkbaş, Gökhan Açıkbaş, Ali Erdem Çerçevik, and Pınar Akpınar. "Turkish Lunar Regolith Simulant TBG-1." In 18th Biennial International Conference on Engineering, Science, Construction, and Operations in Challenging Environments. Reston, VA: American Society of Civil Engineers, 2023. http://dx.doi.org/10.1061/9780784484470.080.

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Gunardi, Jovi, Johny Prihanto, and So Jimmy. "The Increase of Employees Learning and Development by Maximizing Peoplesoft Oracle Software Technology at PT. Indo-Rama Synthetics Tbk." In Proceedings of the First International Conference of Economics, Business & Entrepreneurship, ICEBE 2020, 1st October 2020, Tangerang, Indonesia. EAI, 2021. http://dx.doi.org/10.4108/eai.1-10-2020.2305511.

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Andrian, Andrian, Hadita Hadita, and Jumawan Jumawan. "The Implementation of Corporate Branding and Social Responsibility of PT. Summarecon Agung Tbk Towards Social Welfare in North Bekasi Area." In International Conference on Environmental Awareness for Sustainable Development in conjunction with International Conference on Challenge and Opportunities Sustainable Environmental Development, ICEASD & ICCOSED 2019, 1-2 April 2019, Kendari, Indonesia. EAI, 2019. http://dx.doi.org/10.4108/eai.1-4-2019.2287234.

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Roberts, Kim. "1 Tb/s Coherent Transceiver." In Signal Processing in Photonic Communications. Washington, D.C.: OSA, 2012. http://dx.doi.org/10.1364/sppcom.2012.spw2b.5.

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Liu, Xiang, and S. Chandrasekhar. "Beyond 1-Tb/s superchannel transmission." In 2011 IEEE Photonics Conference (IPC). IEEE, 2011. http://dx.doi.org/10.1109/pho.2011.6110846.

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Inagaki, K., A. Ishikawa, Takanobu Hiroto, K. Tokiwa, T. Fujii, and R. Tamura. "Synthesis and magnetic properties of Au-Ga-Tb 1/1 approximant." In Aperiodic 2018 ("9th Conference on Aperiodic Crystals"). Iowa State University, Digital Press, 2018. http://dx.doi.org/10.31274/aperiodic2018-180810-23.

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Reports on the topic "TBK-1"

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Laurinat, J. E. Mass transfer model for two-layer TBP oxidation reactions: Revision 1. Office of Scientific and Technical Information (OSTI), November 1994. http://dx.doi.org/10.2172/10105398.

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Perez-Polo, J. R., Claire E. Hulsebosch, and Douglas S. DeWitt. Mission Connect Mild TBI Translational Research Consortium: To Study the Role of IL-1 and TNF Receptor Activation in Neurological Deficits after TBI. Fort Belvoir, VA: Defense Technical Information Center, August 2014. http://dx.doi.org/10.21236/ada610986.

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Sneekes, A. C., C. Kwadijk, M. Kotterman, and A. A. Koelmans. Technieken en toepasbaarheid voor de sanering van dioxines en TBT in het Noordzeekanaal : fase 1. IJmuiden: Wageningen Marine Research, 2017. http://dx.doi.org/10.18174/428146.

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Bain, Luchuo Engelbert, and Darja Dobermann. Malaria, HIV and TB in the Democratic Republic of the Congo: Epidemiology, Disease Control Challenges and Interventions. Institute of Development Studies (IDS), March 2022. http://dx.doi.org/10.19088/k4d.2022.034.

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Malaria, human immune deficiency virus (HIV) and tuberculosis (TB) are leading causes of death and public health threat to millions in Democratic Republic of Congo (DRC). The DRC is the second most malaria affected sub-Saharan African country after Nigeria, with malaria being the leading cause of death in children under 5 years (Lechthaler et al., 2019). The HIV prevalence in the country in the adult population stands at 1%, with extensive variations by region (UNAIDS, 2021c). The DRC is considered a high burden country for TB and HIV infection (Linguissi et al., 2017). This rapid review emphasizes significant elements of the epidemiology of malaria, HIV, and TB in DRC, as well as limitations in prevention, detection, and treatment, and examines a few interventions that aim to address these limitations. Evidence utilised is a mixture of the most recent grey literature NGO (programme reports and related documents) literature supplemented by peer reviewed academic literature from the past five years and national survey data when available. Although the clinical disease aspects of malaria, HIV and TB are well-researched there is less research available on socio-demographic variation, disease control challenges and interventions targeting these in the DRC. This is part of a series of reports looking into Epidemiology of Malaria, human immune deficiency virus (HIV) and tuberculosis (TB) across a set of African Nations.
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Bronevetsky, G., and A. Moody. Scalable I/O Systems via Node-Local Storage: Approaching 1 TB/sec File I/O. Office of Scientific and Technical Information (OSTI), August 2009. http://dx.doi.org/10.2172/964079.

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Dickman, Martin B., and Oded Yarden. Role of Phosphorylation in Fungal Spore Germination. United States Department of Agriculture, August 1993. http://dx.doi.org/10.32747/1993.7568761.bard.

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Spore germination is a common and fundamental event in fungal development and in many instances an essential phase of fungal infection and dissemination. Spore germination is also critical for hyperparasites to function as biocontrol agents as well as in fermentation proceses. Our common objective is to understand the mechanisms which regulated spore germination and identify factors involved in pathogenicity related prepenetration development. Our approach is to exploit the overall similarity among filamentous fungi using both a plant pathogen (Colletotricum trifolii) and a model system that is genetically sophisticated (Neurospora crassa). The simulataneous use of two organisms has the advantage of the available tools in Neurospora to rapidly advance the functional analysis of genes involved in spore germination and development of an economically important fungal phytopathogen. Towards this we have isolated a protein kinase gene from C. trifolii (TB3) that is maximally expressed during the first hour of conidial germination and prior to any visible gene tube formation. Based on sequence similarities with other organisms, this gene is likely to be involved in the proliferative response in the fungus. In addition, TB3 was able to functionally complement a N. crassa mutant (COT-1). Pharmacological studies indicated the importance of calmodulin in both germination and appressorium differentiation. Using an antisense vector from N. crassa, direct inhibition of calmodulin results in prevention of differentiation as well as pathogenicity. Both cAMP dependent protein kinase (PKA) and protein kinase C (PKC) like genes have been cloned from C. trifolii. Biochemical inhibition of PKA prevents germination; biochemical inhibitors of PKC prevents appressorium differentiation. In order to analyze reversible phosphorylation as a regulatory mechanism, some ser.thr dephosphorylative events have also been analyzed. Type 2A and Type 2B (calcineurin) phosphatases have been identified and structurally and functionally analyzed in N. crassa during this project. Both phosphatases are essential for hyphal growth and maintenance of proper hyphal architecture. In addition, a first novel-type (PPT/PP5-like) ser/thr phosphatase has been identified in a filamentous fungus. The highly collaborative project has improved our understanding of a fundamental process in fungi, and has identified targets which can be used to develop new approaches for control of fungal plant pathogens as well as improve the performance of beneficial fungi in the field and in industry. In addition, the feasibility of molecular technology transfer in comparative mycology has been demonstrated.
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Lamarque, Hugh. Key Considerations: Cross-Border Dynamics between Uganda and Rwanda in the Context of the Outbreak of Ebola, 2022. SSHAP, November 2022. http://dx.doi.org/10.19088/sshap.2022.044.

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This brief summarises key considerations concerning cross-border dynamics between Uganda and Rwanda in the context of the 2022 outbreak of Ebola (Sudan Virus Disease, SVD) in Uganda. It is part of a series focusing on at-risk border areas between Uganda and four high priority neighbouring countries: Rwanda; Tanzania; Kenya; and South Sudan. The outbreak began in Mubende, Uganda on 19 September 2022, approximately 300 kilometres from the Uganda-Rwanda border. At the time of writing (November 2022) it has spread to nine Ugandan districts, including two in the Kampala metropolitan area. Kampala is a transport hub, with a population over 3.6 million. While the global risk from SVD remains low according to the World Health Organization, its presence in the Uganda capital has significantly heightened the risk to regional neighbours. Rwanda is categorised as Priority 1, with significant preparedness activities underway. As of November 2022, there had been no case of SVD imported from Uganda into Rwanda, although alerts have been triggered at border posts. This brief provides details about cross-border relations, the political and economic dynamics likely to influence these, and specific areas and actors most at risk. It is based on a rapid review of existing published and grey literature, news reports, previous ethnographic research in Rwanda and Uganda, and informal discussions with colleagues from Save the Children, UNICEF, UNECA, UNDP, IOM, TBI, and the World Bank. It was requested by the Collective Service, written by Hugh Lamarque (University of Edinburgh) and supported by Olivia Tulloch (Anthrologica. It was reviewed by colleagues from Save the Children, Anthrologica, the Institute of Development Studies and the Collective Service. This brief is the responsibility of SSHAP.
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Yahav, Shlomo, John Brake, and Orna Halevy. Pre-natal Epigenetic Adaptation to Improve Thermotolerance Acquisition and Performance of Fast-growing Meat-type Chickens. United States Department of Agriculture, September 2009. http://dx.doi.org/10.32747/2009.7592120.bard.

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: The necessity to improve broiler thermotolerance and performance led to the following hypothesis: (a) thethermoregulatory-response threshold for heat production can be altered by thermal manipulation (TM) during incubation so as to improve the acquisition of thermotolerance in the post-hatch broiler;and (b) TM during embryogenesis will improve myoblast proliferation during the embryonic and post-hatch periods with subsequent enhanced muscle growth and meat production. The original objectives of this study were as follow: 1. to assess the timing, temperature, duration, and turning frequency required for optimal TM during embryogenesis; 2. to evaluate the effect of TM during embryogenesis on thermoregulation (heat production and heat dissipation) during four phases: (1) embryogenesis, (2) at hatch, (3) during growth, and (4) during heat challenge near marketing age; 3. to investigate the stimulatory effect of thermotolerance on hormones that regulate thermogenesis and stress (T₄, T₃, corticosterone, glucagon); 4. to determine the effect of TM on performance (BW gain, feed intake, feed efficiency, carcass yield, breast muscle yield) of broiler chickens; and 5. to study the effect of TM during embryogenesis on skeletal muscle growth, including myoblast proliferation and fiber development, in the embryo and post-hatch chicks.This study has achieved all the original objectives. Only the plasma glucagon concentration (objective 3) was not measured as a result of technical obstacles. Background to the topic: Rapid growth rate has presented broiler chickens with seriousdifficulties when called upon to efficiently thermoregulate in hot environmental conditions. Being homeotherms, birds are able to maintain their body temperature (Tb) within a narrow range. An increase in Tb above the regulated range, as a result of exposure to environmental conditions and/or excessive metabolic heat production that often characterize broiler chickens, may lead to a potentially lethal cascade of irreversible thermoregulatory events. Exposure to temperature fluctuations during the perinatal period has been shown to lead to epigenetic temperature adaptation. The mechanism for this adaptation was based on the assumption that environmental factors, especially ambient temperature, have a strong influence on the determination of the “set-point” for physiological control systems during “critical developmental phases.” In order to sustain or even improve broiler performance, TM during the period of embryogenesis when satellite cell population normally expand should increase absolute pectoralis muscle weight in broilers post-hatch. Major conclusions: Intermittent TM (39.5°C for 12 h/day) during embryogenesis when the thyroid and adrenal axis was developing and maturing (E7 to E16 inclusive) had a long lasting thermoregulatory effect that improved thermotolerance of broiler chickens exposed to acute thermal stress at market age by lowering their functional Tb set point, thus lowering metabolic rate at hatch, improving sensible heat loss, and significantly decreasing the level of stress. Increased machine ventilation rate was required during TM so as to supply the oxygen required for the periods of increased embryonic development. Enhancing embryonic development was found to be accomplished by a combination of pre-incubation heating of embryos for 12 h at 30°C, followed by increasing incubation temperature to 38°C during the first 3 days of incubation. It was further facilitated by increasing turning frequency of the eggs to 48 or 96 times daily. TM during critical phases of muscle development in the late-term chick embryo (E16 to E18) for 3 or 6 hours (39.5°C) had an immediate stimulatory effect on myoblast proliferation that lasted for up to two weeks post-hatch; this was followed by increased hypertrophy at later ages. The various incubation temperatures and TM durations focused on the fine-tuning of muscle development and growth processes during late-term embryogenesis as well as in post-hatch chickens.
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Gao, Chunwang. The breakdown of de Gennes Scaling in TbxEr1-xNi2B2C and its mean field theory explanation. Office of Scientific and Technical Information (OSTI), January 2004. http://dx.doi.org/10.2172/850042.

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Yahav, Shlomo, John Brake, and Noam Meiri. Development of Strategic Pre-Natal Cycling Thermal Treatments to Improve Livability and Productivity of Heavy Broilers. United States Department of Agriculture, December 2013. http://dx.doi.org/10.32747/2013.7593395.bard.

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The necessity to improve broiler thermotolerance and live performance led to the following hypothesis: Appropriate comprehensive incubation treatments that include significant temperature management changes will promote angiogenesis and will improve acquisition of thermotolerance and carcass quality of heavy broilers through epigenetic adaptation. It was based on the following questions: 1. Can TM during embryogenesis of broilers induce a longer-lasting thermoregulatory memory (up to marketing age of 10 wk) that will improve acquisition of thermotolerance as well as increased breast meat yield in heavy broilers? 2. The improved sensible heat loss (SHL) suggests an improved peripheral vasodilation process. Does elevated temperature during incubation affect vasculogenesis and angiogenesis processes in the chick embryo? Will such create subsequent advantages for heavy broilers coping with adverse hot conditions? 3. What are the changes that occur in the PO/AH that induce the changes in the threshold response for heat production/heat loss based on the concept of epigenetic temperature adaptation? The original objectives of this study were as follow: a. to assess the improvement of thermotolerance efficiency and carcass quality of heavy broilers (~4 kg); b. toimproveperipheral vascularization and angiogenesis that improve sensible heat loss (SHL); c. to study the changes in the PO/AH thermoregulatory response for heat production/losscaused by modulating incubation temperature. To reach the goals: a. the effect of TM on performance and thermotolerance of broilers reared to 10 wk of age was studied. b. the effect of preincubation heating with an elevated temperature during the 1ˢᵗ 3 to 5 d of incubation in the presence of modified fresh air flow coupled with changes in turning frequency was elucidated; c.the effect of elevated temperature on vasculogenesis and angiogenesis was determined using in ovo and whole embryo chick culture as well as HIF-1α VEGF-α2 VEGF-R, FGF-2, and Gelatinase A (MMP2) gene expression. The effects on peripheral blood system of post-hatch chicks was determined with an infrared thermal imaging technique; c. the expression of BDNF was determined during the development of the thermal control set-point in the preoptic anterior hypothalamus (PO/AH). Background to the topic: Rapid growth rate has presented broiler chickens with seriousdifficulties when called upon to efficiently thermoregulate in hot environmental conditions. Being homeotherms, birds are able to maintain their body temperature (Tb) within a narrow range. An increase in Tb above the regulated range, as a result of exposure to environmental conditions and/or excessive metabolic heat production that often characterize broiler chickens, may lead to a potentially lethal cascade of irreversible thermoregulatory events. Exposure to temperature fluctuations during the perinatal period has been shown to lead to epigenetic temperature adaptation. The mechanism for this adaptation was based on the assumption that environmental factors, especially ambient temperature, have a strong influence on the determination of the “set-point” for physiological control systems during “critical developmental phases.” Recently, Piestunet al. (2008) demonstrated for the first time that TM (an elevated incubation temperature of 39.5°C for 12 h/d from E7 to E16) during the development/maturation of the hypothalamic-hypophyseal-thyroid axis (thermoregulation) and the hypothalamic-hypophyseal-adrenal axis (stress) significantly improved the thermotolerance and performance of broilers at 35 d of age. These phenomena raised two questions that were addressed in this project: 1. was it possible to detect changes leading to the determination of the “set point”; 2. Did TM have a similar long lasting effect (up to 70 d of age)? 3. Did other TM combinations (pre-heating and heating during the 1ˢᵗ 3 to 5 d of incubation) coupled with changes in turning frequency have any performance effect? The improved thermotolerance resulted mainly from an efficient capacity to reduce heat production and the level of stress that coincided with an increase in SHL (Piestunet al., 2008; 2009). The increase in SHL (Piestunet al., 2009) suggested an additional positive effect of TM on vasculogenesis and angiogensis. 4. In order to sustain or even improve broiler performance, TM during the period of the chorioallantoic membrane development was thought to increase vasculogenesis and angiogenesis providing better vasodilatation and by that SHL post-hatch.
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