Dissertations / Theses on the topic 'Tank gun'
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Lee, S. T. "A study of human tracking performance using different gun aiming controllers in a simulated A.F.V. vibration environment." Thesis, Cranfield University, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.277509.
Full textBuyukcivelek, Firat. "Analysis And Control Of Gun Barrel Vibrations." Master's thesis, METU, 2011. http://etd.lib.metu.edu.tr/upload/12613942/index.pdf.
Full textKarayumak, Turker. "Modeling And Stabilization Control Of A Main Battle Tank." Phd thesis, METU, 2011. http://etd.lib.metu.edu.tr/upload/12613767/index.pdf.
Full textЛазаренко, Артем Александрович. "Синтез и разработка инвариантных систем стабилизации основного вооружения танков." Thesis, НТУ "ХПИ", 2016. http://repository.kpi.kharkov.ua/handle/KhPI-Press/22727.
Full textThe thesis for the degree of candidate of technical sciences, specialty 05.13.03 – Systems and management processes. – National Technical University "Kharkov Polytechnic Institute", Kharkov – 2016. The thesis is dedicated to development analog and digital invariant guidance systems and stabilize the main armament of tanks through the creation of mathematical models perturbed motion tank gun relative to the axis of the pins and the tank tur ret gun relative to the axis of rotation, as well as simulation models of external disturbances acting on the main armament channels vertical and horizontal guidance. It is shown that increasing the degree of invariance closed stabilization system to external perturbations lead to lower stability margin closed system. To maintain the desired stability margin suggested the introduction of the system of additional feedback path for the angular acceleration of the object of stabilization. The features invariant digital stabilization system tank gun, including the need to use a digital low-pass filter Batteruorta and Lanczos filtering high frequency noise output signals of sensors. It is proved that the construction of a digital stabilizer tank cannon appropriate series-parallel use of digital filters Batteruorta and Lanczos. The structure created and the choice of variable constants stabilization algorithms was made that provide an invariance closed system of guidance and stabilization without significantly reducing its stability margin. Modeling of guidance and stabilization in a closed system with subsequent analysis of these processes suggests a significant increase in accuracy working off of external perturbation (at 1.8 – 1.9 times) compared with the standard.
Лазаренко, Артем Олександрович. "Синтез і розробка інваріантних систем керування наведенням та стабілізацією основного озброєння танків." Thesis, НТУ "ХПІ", 2016. http://repository.kpi.kharkov.ua/handle/KhPI-Press/22726.
Full textThe thesis for the degree of candidate of technical sciences, specialty 05.13.03 – Systems and management processes. – National Technical University "Kharkov Polytechnic Institute", Kharkov – 2016. The thesis is dedicated to development analog and digital invariant guidance systems and stabilize the main armament of tanks through the creation of mathematical models perturbed motion tank gun relative to the axis of the pins and the tank tur ret gun relative to the axis of rotation, as well as simulation models of external disturbances acting on the main armament channels vertical and horizontal guidance. It is shown that increasing the degree of invariance closed stabilization system to external perturbations lead to lower stability margin closed system. To maintain the desired stability margin suggested the introduction of the system of additional feedback path for the angular acceleration of the object of stabilization. The features invariant digital stabilization system tank gun, including the need to use a digital low-pass filter Batteruorta and Lanczos filtering high frequency noise output signals of sensors. It is proved that the construction of a digital stabilizer tank cannon appropriate series-parallel use of digital filters Batteruorta and Lanczos. The structure created and the choice of variable constants stabilization algorithms was made that provide an invariance closed system of guidance and stabilization without significantly reducing its stability margin. Modeling of guidance and stabilization in a closed system with subsequent analysis of these processes suggests a significant increase in accuracy working off of external perturbation (at 1.8 – 1.9 times) compared with the standard.
Kim, Oh Hyun. "Atomic layer deposition of GaN and TaN." [Gainesville, Fla.] : University of Florida, 2009. http://purl.fcla.edu/fcla/etd/UFE0025153.
Full textParente, Peter Bishop Gary. "Clique perceptually based, task oriented auditory display for GUI applications /." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2008. http://dc.lib.unc.edu/u?/etd,1983.
Full textTitle from electronic title page (viewed Dec. 11, 2008). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Computer Science." Discipline: Computer Science; Department/School: Computer Science.
Yung, Yu-hon Edward, and 翁餘漢. "A study of Hong Ying Ming's Cai Gen Tan." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B46701187.
Full textChen, Lie. "Tan tao hua tan qu yu fang yao zhi liao guan xin bing de lin chuang ying yong jia zhi /." click here to view the abstract and table of contents, 2006. http://net3.hkbu.edu.hk/~libres/cgi-bin/thesisab.pl?pdf=b19986956a.pdf.
Full textSo, Wai-man. "A study of eunuchs in Tang and Northern Song China = Tang yu bei song huan guan yan jiu /." Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B24702444.
Full textNg, Ho-kei. "Views on Sino-Barbarian relations as seen in the officially compiled histories in the early Tang Lun Tang chu guan xiu shi shu zhong de Hua yi guan /." Click to view the E-thesis via HKUTO, 1995. http://sunzi.lib.hku.hk/hkuto/record/B3195084X.
Full textElfgaard, Matilda. "Tack gode Gud för Stretchjeansen! : -En studie om "kastartjejers" syn på kropp och ideal." Thesis, Linnéuniversitetet, Institutionen för idrottsvetenskap (ID), 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-45279.
Full textLin, Tengfan. "A GUI Design of Robot Motion and Task Planning Based on Linear Temporal Logic." Thesis, KTH, Skolan för elektroteknik och datavetenskap (EECS), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-235307.
Full textNya metoder lösa problemet med robot motion och task planningmed hjälp av formella metoder-baserade modellkontroll algoritmer. Idetta exjobb anser vi att programvarupaketet P-MAS-TG, ett automatisktverktyg för att generera correct-by-design controllers för robotmotion och task planning. Robot motion kan modelleras som ett ändligttillstånd övergångssystem och uppgiften kan representeras av enlinjär temporal logik formel. Sedan, med hjälp av en modellkontrollalgoritm, kan en accepterande väg för roboten rörelse hittas så att robotenuppfyller de specifika linjära temporala logik uppgift. I dennauppsats processen att söka efter den accepterande sökvägen till robotmotion av P-MAS-TG visualiseras med hjälp av ett grafiskt användargränssnitt(GUI) i form av en rqt plug-in där alla efterfrågade indataför P-MAS-TG-paketet kan definieras i GUI så att process är förenklatoch användarvänligt. Dessutom ger GUI en enkel hybrid kontrollmekanismmellan den ursprungliga linjära temporala logisk uppgift ochen tillfällig uppgift som infogas av en människa.Alla funktioner i GUI implementeras och demonstreras på TurtleBotplattformen.Experimentet visar att GUI och P-MAS-TG är framgångsriktintegrerade. Egenskaper hos P-MAS-TG utförs med GUI för attgenomföra motion planning och task planning på TurtleBot.
Fang, Guohui. "Man xing xie xie pi xu zheng zheng zhi gui lü chu tan /." click here to view the abstract and table of contents, 2006. http://net3.hkbu.edu.hk/~libres/cgi-bin/thesisab.pl?pdf=b19987031a.pdf.
Full textXiong, Jiawei. "Zhen jiu zhi liao tong jing de qu xue gui lü tan tao /." click here to view the abstract and table of contents, 2006. http://net3.hkbu.edu.hk/~libres/cgi-bin/thesisab.pl?pdf=b19987055a.pdf.
Full textLindvall, Erik. ""More dangerous than guns and tanks" : How cybersecurity is framed by the EU and Sweden." Thesis, Uppsala universitet, Statsvetenskapliga institutionen, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-412928.
Full textGoh, Yen-Lin. "Reimagining the Story of Lu You and Tang Wan: Ge Gan-ru's Wrong, Wrong, Wrong! and Hard, Hard, Hard!" Bowling Green State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1349118390.
Full textChan, Hing-yun Roger. "The taoists and politics in the T'ang dynasty Tang dai Dao jia ren shi yu zheng zhi zhi guan xi /." Click to view the E-thesis via HKUTO, 1985. http://sunzi.lib.hku.hk/hkuto/record/B31948479.
Full textHuang, Shaofen. "Zhen ci dui ying ji fan ying zhong xue ya he xin shuai de ying xiang ji qi ji li tan tao : wen xian zong shu /." click here to view the abstract and table of contents, 2006. http://net3.hkbu.edu.hk/~libres/cgi-bin/thesisab.pl?pdf=b20009537a.pdf.
Full textLeung, Sze-lok, and 梁思樂. "A study on the locations of capitals and the planning of administrative districts in the Tang, Song and Yuan dynasties = Tang, Song, Yuan san zhao guo du xuan zhi yu zheng qu gui hua yan jiu." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/196084.
Full textpublished_or_final_version
Chinese
Doctoral
Doctor of Philosophy
Ma, Koon-yiu. "The development of Hong Kong structural engineering standards after the Second World War and before 1997 Zhan hou dao hui gui qian Xianggang jie gou gong cheng gui fan fa zhan de tan tao /." Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/hkuto/record/B3862073X.
Full textCheng, Wing Kin. "Mou Zongsan xian sheng li jie Laozi zhe xue de ping xi : dui "zhi de zhi jue" he "zong guan" liang gai nian zhi tan tao /." View abstract or full-text, 2009. http://library.ust.hk/cgi/db/thesis.pl?HUMA%202009%20CHENG.
Full textChung, Chi-kwong. "The relationship between recitation and Chinese literature a study through Du Fu's poems = Cong Du Fu shi tan lang song yu Zhongguo wen xue de guan xi /." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B41547275.
Full textVale, Marcelo Roberto Bastos Guerra. "An?lise comparativa do desempenho de um Controlador Fuzzy acoplado a um PID Neural sintonizado por um Algoritmo Gen?tico com Controladores Inteligentes Convencionais." Universidade Federal do Rio Grande do Norte, 2007. http://repositorio.ufrn.br:8080/jspui/handle/123456789/15184.
Full textOn this paper, it is made a comparative analysis among a controller fuzzy coupled to a PID neural adjusted by an AGwith several traditional control techniques, all of them applied in a system of tanks (I model of 2nd order non lineal). With the objective of making possible the techniques involved in the comparative analysis and to validate the control to be compared, simulations were accomplished of some control techniques (conventional PID adjusted by GA, Neural PID (PIDN) adjusted by GA, Fuzzy PI, two Fuzzy attached to a PID Neural adjusted by GA and Fuzzy MISO (3 inputs) attached to a PIDN adjusted by GA) to have some comparative effects with the considered controller. After doing, all the tests, some control structures were elected from all the tested techniques on the simulating stage (conventional PID adjusted by GA, Fuzzy PI, two Fuzzy attached to a PIDN adjusted by GA and Fuzzy MISO (3 inputs) attached to a PIDN adjusted by GA), to be implemented at the real system of tanks. These two kinds of operation, both the simulated and the real, were very important to achieve a solid basement in order to establish the comparisons and the possible validations show by the results
Neste trabalho ?realizado uma an?lise comparativa entre um controlador fuzzy acoplado aum PID neural ajustado por um AGcom diversas t?cnicas de controle tradicionais, todas elas aplicadas em um sistema de tanques (modelo de 2a ordem n?o linear). Com o objetivo de viabilizar as t?cnicas envolvidas nas an?lises comparativas e validar o controle a ser comparado, foram realizadas simula??es de algumas t?cnicas de controle (PID convencional ajustado por AG, PID Neural (PIDN) ajustado por AG, Fuzzy PI, Fuzzy cascata acoplado a um PIDN ajustado por AG e Fuzzy MISO (3 entradas) acoplado a um PIDN ajustado por AG) para efeitos comparativos com o controlador proposto. Depois de realizar todos os testes simulados, foram eleitas, dentre as t?cnicas testadas na fase de simula??o, algumas estruturas de controle (PID convencional ajustado por AG, Fuzzy PI, Fuzzy cascata acoplado aum PIDN ajustado por AGeFuzzy MISO (3entradas) acoplado a um PIDN ajustado por AG) para serem implementadas no sistema real de tanques. Esses dois modos de opera??o, tanto o simulado como o real, se fizeram importantes para um embasamento s?lido para fazer as compara??es e valida??es poss?veis mostradas nos resultados
Wong, Hon-meng, and 黃漢明. "Non-mainstream intellectual phenomenon in the mid-Tang period : characteristics of Dan Zhu's (724-770) Chun qiu study and related social background = Zhong Tang ru xue si xiang de yi cai : Dan Zhu (724-770) zhi "Chun qiu" de te dian ji qi xiang guan she hui bei jing." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/197550.
Full textpublished_or_final_version
Chinese
Master
Master of Philosophy
Senate, University of Arizona Faculty. "Faculty Senate Minutes April 2, 2012." University of Arizona Faculty Senate (Tucson, AZ), 2012. http://hdl.handle.net/10150/222812.
Full textRennu, Samantha R. "Dynamic Mission Planning for Unmanned Aerial Vehicles." University of Dayton / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=dayton16082274381124.
Full textNordin, Ellinor. "Assessment of balance control in relation to fall risk among older people." Doctoral thesis, Umeå universitet, Samhällsmedicin och rehabilitering, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1933.
Full textSilva, Paulo S?rgio e. "Automa??o da drenagem no teste de produ??o convencional em tanque cil?ndrico." Universidade Federal do Rio Grande do Norte, 2009. http://repositorio.ufrn.br:8080/jspui/handle/123456789/12893.
Full textThis document aims to improve the quality of the production test in vertical tanks with free water drain pipes, through a device to control the draining system. This proposal consists of an interface detector close to the tank bottle and a control valve on the pipe-drain; they are attached to a remote supervisor system, which will be minimizing the human influence in the conclusion of the test result. And for more consciousness the work shows the importance of the wells production test in the attendance and diagnosis of the productive process, informing the large number of tests executed and problems of the procedure adopted in the field today. There are many possible sources of uncertainty in this kind of test as shown in the experiments realized in the field; the object prototype of this dissertation will be made in the field, based upon the definition of parameters and characteristics of the devices proposal. For a better definition of the draining process the action results of the assessment test are shown, especially changed some for the understand ing of the real process. It shows the proposal details and the configuration that will be used in the tank of Monte Alegre s field Production Station, explaining the interface detector kind and the control system. It is the base to a pilot project now in development, named as the new project classified in the status of the new technology and production improvement of PETROBRAS in Rio Grande do Norte and Cear?. This dissertation concludes that the automation of the conventional test with the draining system will bring benefits both economically as metrologically, because it reduces the uncertainty of the test procedures with free water draining, and also decreases the number of tests with problems
Este trabalho tem por objetivo melhorar a qualidade dos testes de produ??o em tanques verticais com drenagem da ?gua livre, atrav?s da instala??o de dispositivos para controle autom?tico do sistema de drenagem do tanque. Esta proposta de melhoria consiste na montagem de um detector de interface pr?ximo do fundo do tanque e uma v?lvula de controle no dreno, interligados a um sistema de supervis?o remota, reduzindo a influ?ncia humana na finaliza??o e resultados do teste. O trabalho mostra a import?ncia do teste de produ??o dos po?os para o acompanhamento e diagn?stico do processo produtivo, atrav?s da cita??o da grande quantidade de testes realizados e das dificuldades do procedimento atualmente adotado. Existem muitas poss?veis fontes de incerteza neste tipo de teste, que foram constatadas por experimentos realizados no campo. O prot?tipo do objeto desta disserta??o ser? montado no campo, tendo como base a defini??o dos par?metros e caracter?sticas dos dispositivos desta proposta. Para melhor definir o processo de drenagem s?o mostrados os resultados das a??es de acompanhamento de testes, especialmente modificados para entendimento da problem?tica do processo atual. Com base nos resultados das pesquisas foi poss?vel detalhar a proposi??o de melhoria, e definir a configura??o a ser montada no tanque de teste da Esta??o Coletora do campo de Monte Alegre, inclusive o tipo de detector de interface e o sistema de controle a ser adotado. O resultado deste trabalho serviu de base para o projeto do piloto atualmente em implanta??o, com conclus?o prevista para abril/2009. Este piloto est? registrado como o projeto classificado na categoria de novas tecnologias e melhoria da produ??o da PETROBRAS, Unidade de Neg?cios do Rio Grande do Norte e Cear?. Esta disserta??o conclui que a automa??o do sistema de drenagem do teste convencional trar? benef?cios tanto econ?micos como metrol?gicos ao minimizar a incerteza do procedimento de teste com drenagem da ?gua livre e conseq?ente redu??o do n?mero de testes falhos
Ke, Michael Bing-Huang. "The marital relationship of Chinese urban Christian intellectuals exploratory analysis and program recommendations = Ni nong wo nong : Zhongguo cheng shi jidu tu zhi shi fen zi hun yin guan xi de tan tao yu dui ce /." Theological Research Exchange Network (TREN) Theological Research Exchange Network (TREN) Access this title online, 2006. http://www.tren.com.
Full textLee, Che-hung. "Guangzhou fang yan yong yu "du" gan rao xue sheng shu mian yu xue xi qing kuang chu tan A study on the influence of the Cantonese word "Dou" in the learning of written Chinese of Hong Kong students /." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B42554275.
Full textXie, Shuxiang. "Dao jin zi ta shi xin wen bao dao de yu pian gui lü : yi Xianggang "Ming bao" she hui xin wen wei yu liao de tan tao = Discourse principles in inverted pyramid news reporting : study of the social news of Ming Pao /." click here to view the abstract and table of contents, 2001. http://net3.hkbu.edu.hk/~libres/cgi-bin/thesisab.pl?pdf=b17041193a.pdf.
Full textXiao, Yunqi. "Ren shi guang gao bei hou de wen hua jia zhi guan : yi nei rong fen xi tan tao Zhongguo da lu ji Xianggang de hu fu / hua zhuang pin za zhi guang gao zhong biao da de "yang hua" jia zhi /." click here to view the abstract and table of contents, 2005. http://net3.hkbu.edu.hk/~libres/cgi-bin/thesisab.pl?pdf=b19816315a.pdf.
Full textBaláž, Martin. "Nové techniky návrhu celulárních automatů." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2013. http://www.nusl.cz/ntk/nusl-412878.
Full textWang, Lianghe. "Shi guan de chong tu yu zhu liu de jing zhu : Xianggang ba, jiu shi nian dai shi tan de liu pai fen zheng--yi "Zhong Weimin xian xiang" ying zhao = The clash of poetic views and striving to be the centre : an exploration of the conflict between poetic schools in the 1980s and 90s in Hong Kong in the light of the "Chung Wai Man phenomenon" /." click here to view the abstract and table of contents, 2001. http://net3.hkbu.edu.hk/~libres/cgi-bin/thesisab.pl?pdf=b17040474a.pdf.
Full textLiu, Chia-Hung, and 劉家宏. "Tank Gun Stabilization Control." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/95987739259773447560.
Full text逢甲大學
自動控制工程研究所
86
This thesis studies the gun stabilizing control of a battle tank. This study formulates the problem and proposes a control strategy to stabilize the gun. The result provides the National Army an initial guideline for the stabilization system design of the development of the third generation battle tank.The system is modeled as the gun and turret on a moving base. The kinematics and the dynamic equations are derived. The system is stabilized by applying a feedback linearization technique in the inner loop and two PD controllers in the outer loop. The parameters of the PD controller are found by an experimental design method in which the variation of the mass of the turret are consider. Thus, the robustness with respect to the variation of the mass is guaranteed.The simulation results show that comparing with the case without control, the control strategy can reduce the disturbance more than 25 dB.
Pojikar, Pavel. "Výroba zbraní pro Wehrmacht a armády spojenců Německa v českých zbrojovkách za Protektorátu Čechy a Morava v letech 1939-1945." Master's thesis, 2011. http://www.nusl.cz/ntk/nusl-313485.
Full textTsai, Yueh-Hsuan, and 蔡岳軒. "Pharmacokinetic Studies of Bioactive Constituents between Commercial Extract and Traditional Decoction of Ge-Gen Tang, Shu-Ching-Huo-Hsieh Tang and Shao-Yao-Gan-Cao Tang." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/43617008289360615274.
Full text高雄醫學大學
藥學研究所
100
The study aims to evaluate the pharmacokinetic differences of bioactive constituents between commercial extract and traditional decoction of Ge-Gen Tang, Shu-Ching-Huo-Hsieh Tang and Shao-Yao-Gan-Cao Tang. The rapid and sensitive quantitative methods for glycyrrhizin and paeoniflorin in plasma samples are developed and validated by using HPLC. After oral administration of Ge-Gen Tang, Shu-Ching-Huo-Hsieh Tang and Shao-Yao-Gan-Cao Tang, the plasma levels-time profiles of glycyrrhizin were adequately described by an one-compartment model. The results showed that after oral administration of commercial extract in New Zealand rabbit, the AUC 0-∞, C max is significantly larger than traditional decoction in GT (AUC 0-∞: 49.28 ± 16.9 and 17.89 ± 2.01; C max : 3.61 ± 0.25 μg/ml and 1.24 ± 0.16 μg/ml), the T max in decoction was shorter than commercial extract of SYGCT (T max 6.89 hr and 10.94 hr), and after oral administration SCHACHT showing same result. The T max of traditional decoction was 7.08 hr and of commercial extract was 8.30 hr. So the pharmacokinetic results are useful for quality control and clinical pharmacokinetic studies of commercial extracts and traditional decoctions of GT, SCHHT and SYGCT.
Hofmann, Filip. "Vliv střelecké polohy vstoje na přesnost opakovaných výstřelů Hard Task Rangers." Master's thesis, 2019. http://www.nusl.cz/ntk/nusl-404151.
Full textHuang, Shang-Pang, and 黃上邦. "Antiviral activity of Sheng-Ma-Ge-Gen-Tang." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/33380878737850216163.
Full text中國醫藥學院
中國醫學研究所
84
Sheng-Ma-Ge-Gen-Tang was used to examined for the antiviral activity against measles virus in human peripherial blood mononuclear cells (PBMC) and Vero cells. 100 μg/ml of Sheng-Ma-Ge-Gen-Tang in PBMC showed significant anti-measles activity, whereas that of in Vero cells were not. After eight days of infection, the release of virus were completely suppresis by Sheng-Ma-Ge-Gen-Tang in PBMC. Furthermore, Sheng- Ma-Ge-Gen-Tang has a significant selective stimulating effect on the secretion of cytokine TNF-a in PBMC. Time kinetic analysis indicated that the stimulation of secretion was rapid and detected as soon 2 hrs following stimulation of the PBMC and raised to optimal amount at 8-12 hrs. These suggest that the magnification of anti-measles activity of this agent is lymphocyte dependent and may mediate by TNF-a.
YANG, HSIU_ MI, and 楊琇米. "Quality Evaluation of Three Chinese Herbal Extracted Preparations - Ma-Xing-Gan-Shi Tang , Si-Ni-San and Wn-Tan-Tong Produced in Taiwan." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/06201597417069064455.
Full text中國醫藥學院
中國藥學研究所
91
Summary Quality Evaluation Three Chinese Herbal Extracted Preparations Produced in Taiwan of Ma-Xing-Gan-Shi Tang ,Si Ni San, and Wn Tan Tong by Hsiu Mi Yang Graduate Institute of Chinese Pharmaceutical Sciences China Medical College There are more than 20 Pharmaceutical factories manufacturing extracted Powder preparations of Chinese crude drugs in Taiwan. The market price of these preparations varied from company to company. We compared the quality of these preparations and also evaluated the quality between the Chinese herbal formulas preparations and the tranditional Chinese crude drugs. This project selected five most commonly used Chinese herbal formulas preparations ( Ma Xing Gan Shi Tang, Si Ni San, Wn Tan Tong ) used in the China Medical College Hospital. We evaluated the quality between the Chinese herbal formulas preparations and the traditional Chinese crude drug based on the following parameters : ( 1 ) Loss on drying ( 2 ) Total ash content ( 3 ) Acid insoluable ash content ( 4 ) Dilute alcohol extract content We also used TLC, HPLC to compare the quality of preparations between the pharmaceutical factories. The analysis showed the quality of products from different factories varied dramatically. The National Health Bureau should enforce the quantitive analysis of the herbal products so as to guarantee their quality. Finally, we wish the Bureau of National Health Insurance can offer different rates to the healthy organizations, based on the quality of herbal preparations so as to improve the quality of the treatment and accelerate the quality control of G.M.P. products.
Tsai, Huei-Chu, and 蔡蕙曲. "Pharmacokinetic and Bioavailability studies of Shaur-Yaw-Gan-Tsao-Tang." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/11183350801087617940.
Full text中國醫藥學院
中國藥學研究所
86
Shaur-Yaw-Gan-Taso-Tang(SYGTT),an traditional formula in China,consists of the two crude drugs:Glycyrrhiza Rhizoma and Paeoniflorin Radix,prosses sedative、analgesic and antispasmodic effects。In this study,the pharmacokinetics and bioavailability of the SYGTT in rabbits were evaluated。A method for simultaneous determination of the active constituents of the SYGTT,included glycyrrhizic acid and paeoniflorin in plasma by self-developed HPLC assay was described。 Six rabbits are randomize arrangement to receive each of glycyrrhizic acid and paeoniflorin mixed IV injection or SYGTT IV injection or SYGTT oral solution under cross-over design。 After IV administration of the SYGTT(contains glycyrrhizic acid 15.84 mg/ml,paeoniflorin 10.56 mg/ml) to the rabbits ,the plasma level-time courses of these two compounds could be adequately described by an open two-compartment model。The elimination half- Life glycyrrhizic Acid and paeoniflorin were 195 and 55 minutes respectively。 The absolute bioavailability of these two compounds after oral administration of the SYGTT solution were 3 and 5 % for glycyrrhizic Acid and paeoniflorin respectively 。This result suggest that repeated dose is necessary for SYGTT in clinical use。
Liu, Wei-Te, and 劉偉德. "Pharmacokinetic and Bioavailability studies of Ger-Gen-Chyn-Lian-Tang." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/72457069193308935991.
Full text中國醫藥學院
中國醫藥研究所
86
The pharmacokinetic and bioavailability of Ger-gen-Chyn-Lian-Tang (GGCLT) , an traditional Chinese formula contains Puerariae Radix , Scutellariae Radix , Coptidis Rhizoma and Glycyrrhizae Radix , were evaluated in rabbits. An HPLC method for simultaneous determination of Puerarin . Baicalin and Berberine in both preparation and plasma samples was self-developed in this study. Six rabbits are randomize arrangement to rechive each of Puerarin . Baicalin . and Berberine mixed I.V. injection ; GGCLT I.V. injection or GGCLT oral solution . under cross-over design . It found that , the pharmacokinetics of these three constituents in rabbit were will fitted an open two compartment model , and the plasma half-life were about 22.15 , 68.52and 169.47 mins for puerarin . baicalin and berberine , respectively . After oral administration the GGCLT in rabbit , the absolute bioavailability of puerarin . baicalin and berberine were 5.71 . 4.30 and 15.99% , respectively, indicated that the poorly absorption of these three constituents from GI tract in rabbits. This result suggest that repeated dose is necessary for GGCLT in clinical use.
Huang, Hsiang-Ling, and 黃湘玲. "Antidepressant effect of Gan-Mai-Dazao-Tang and its ingredients." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/40455710238938087200.
Full text國立臺灣大學
食品科技研究所
96
Depression is a kind of psychiatric disorders that affects more than 10% of the general population. The clinical treatments used nowadays always cause several side-effects such as losing body weight and reducing appetite. Therefore, we expect to look for the alternative treatment simultaneous with antidepressant effect and less side-effect. Gan-Mai-Dazao-Tang is a traditional decoction used to treat depression and anxiety. The ingredients of Gan-Mai-Dazao-Tang include Glycyrrhiza uralensis Fisch. (licorice), Triticum aestivum L. (wheat) and Zizyphus jujuba Mill. (jujube). It can nourish the heart, tranquilize the mind, invigorate the spleen and replenish qi (氣) in the traditional Chinese medicine. The objective of this study is to investigate the antidepressant effects of Gan-Mai-Dazao-Tang and its ingredients in rats on the forced-swim test (FST) – an animal model for predicting the clinical efficacy of antidepressants. Eight-week-old male Nerl: Wistar rats were randomized to C (10 mL/kg bw dd H2O), L (0.4 g/kg bw licorice extract), W (1.6 g/kg bw wheat extract), J (0.5 g/kg bw jujube extract), LWJ [2.5 g/kg bw of complex extract (licorice: wheat: jujube = 5:20:6)] and P (18 mg/kg bw Prozac) groups. Samples were administered by gavage for 21 days. After FST, the animals were sacrificed and their brains were collected for monoamines analysis. The results have shown that the body weight and the appetite of rats were significantly lowered in P group (p<0.05), while the other groups were not significantly different with each other. The immobility time in FST was significantly decreased in LWJ and P group compared with control (p<0.05), but the ingredients of Gan-Mai-Dazao-Tang showed no significantly antidepressant effect in FST. The concentration of serotonin (5-HT) in frontal cortex were significantly higher in LWJ and P group compared with control (p<0.05), although 5-hydroxyindoleacetic acid in frontal cortex and amygdale were not significantly different between LWJ and the control group. However, administration of LWJ and P significantly increased the dopamine (DA) concentration (p<0.05) and decreased the concentration of 3,4-dihydroxyphenylacetic acid (DOPAC) (p<0.05) and DOPAC/DA turnover (p<0.05) in striatum compared to the control. The results indicate that Gan-Mai-Dazao-Tang may have the potential antidepressant effect and less side-effect in rats.
Wei, Hung-Chi, and 魏宏吉. "Hemodynamic effects of Long-Dan-Xie-Gan-Tang on cirrhotic rats." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/46936774306836456629.
Full text國立陽明大學
傳統醫藥學研究所
89
Portal hypertension is a major complication of liver cirrhosis. Cirrhosis and portal hypertension are associated with abnormalities in the cardiovascular system, with the development of a hyperkinetic circulatory state characterized by an increase in cardiac output, portal pressure, splanchnic blood flow and a decrease in arterial blood pressure and peripheral vascular resistance. Pharmacological therapy of portal hypertension aims to reduce portal blood inflow and/or intra-hepatic resistance. Long-Dan-Xie-Gan-Tang (LDXGT) is a commonly used traditional Chinese medicine in patients with chronic liver diseases in Taiwan. The hemodynamic effects of LDXGT in cirrhotic rats have not been explored. Although there are clinical reports showing portal hypotensive effects of carvedilol, a non-selectiveβ-adenoceptor antagonist withα1- adenoceptor antagonistic activity, the detailed hemodynamic effects in cirrhotic rats are also lacking. Propranolol, a β-adenoceptor antagonist, has been reported to reduce portal pressure in patients with cirrhosis, but the detailed hemodynamic effects in cirrhotic rats remain unclear. The present study was aimed to investigate the hemodynamic effects of LDXGT, carvedilol and propranolol administration in cirrhotic rats. Portal hypertension with cirrhosis was induced by chronic bile duct ligation (CBDL) in Sprague-Dawley rats (230 ~ 250 g). Cirrhotic rats were allocated into separate groups: CBDL-Treatment group and CBDL-Vehicle group. Sham-operated rats served as controls. LDXGT and carvedilol was administered for 1-Week or 4-Week by gavage, starting at 3 weeks after ligation or at the time of ligation, respectively. Hemodynamic studies were performed by radioactive microsphere method after an overnight fast. We also investigate whether acute LDXGT i.v. infusion exerted a direct vasopressor effect by thermodilution method. Our results showed that: (1) 1-Week carvedilol (5 mg/kg, bid, p.o.) administration partially ameliorated the hyperdynamic state of CBDL rats, including a significant decrease in heart rate, cardiac index, portal pressure, portal tributary blood flow and renal blood flow and an increase in systemic vascular resistance and renal vascular resistance. (2) 1-Week propranolol (15mg/kg, bid, p.o.) administration also partially ameliorated the hyperdynamic state of CBDL rats. (3) 1-Week LDXGTH (333 mg/kg, bid, p.o.) administration only caused a significant decrease in cardiac index and an increase in systemic vascular resistance. However, splanchnic hyperdynamic state did not changed after 1-Week LDXGTH administration. (4) 4-Week LDXGTH administration not only significantly ameliorated systemic hyperdynamic state but also caused a beneficial effect in splanchnic hyperdynamics, including a decrease in portal venous pressure and an increase in portal territory as well as renal vascular resistance. (5) 4-Week LDXGTL (111 mg/kg, bid, p.o.) administration exerted beneficial effects in both systemic and splanchnic hyperdynamic state. However, there was not a dose response relationship between 4-Week LDXGTL and LDXGTH administration. (6) Acute LDXGT i.v. infusion seems not to exert a vasopressor effect. Our results suggested that 1-Week carvedilol, propranolol and 4-Week LDXGT treatment may provide beneficial effects in the management of portal hypertension and hyperdynamic circulation on cirrhotic rats.
Kung, Jinn-huei, and 龔進輝. "A study of Wang Tong-Gui''s Er Tan and Er Tan Lei Zeng." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/68194608503224109985.
Full text雲林科技大學
漢學資料整理研究所碩士班
98
In Ming Dynasty, in addition to Jian Deng and Yan Yi series, there were many other fictions about contemporary concern, social reflection, and ideology. Among them, Wang Ton-Ggui'' s Er Tan was one of the best, which was welcomed by the readers, became the material resources of short stories and dramas, and influenced the later records strange or supernatural events novel such as Liao Zhai Zhi Yi. However, the circulation of Er Tan became very rare since Qing Dynasty. Recently, there were researches on the evolution and preservation of folk stories in Er Tan, but the author’s life and the printing era of the fiction still remain questioned. This article aims to answer these questions about author and printing era, and to illustrate the importance of Er Tan in Chinese fiction evolution by discussing the citation of the fiction in other books, especially in Gu Jin Tan Gai.
Cheng, An Bin, and 鄭安斌. "Ger-Gen-Chyn-Lian-Tang attenuates thioacetamide-induced hepatic injury in mice." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/56105633706336316793.
Full text長庚大學
中醫學系傳統中醫學
101
Chronic liver injury results from repeatedly hepatic injury with persistent inflammation, hepatic stellate cell activation with scar formation and loss of normal architecture. Chronic inflammation is a common element in the pathogenesis of most chronic liver diseases which lead to liver fibrosis and cirrhosis. Ger-Gen-Chyn-Lian-Tang (GGCLT) is originally compiled by Zhang Zhong-Jing in Han dynasty. It has been shown to have biological effects including antioxicant and anti-inflammation. Its major constituents including puerarin, baicalin, berberine and glycyrrhizin also exhibit anti-inflammation and hepatoprotective effects. This study investigates the protective effects of GGCLT against chronic liver injury induced by thioacetamide (TAA) and the mechanism of its hepatoprotective effects. Male C57BL/6 mice were divided into six groups: normal control group, TAA 2wks group, TAA 4wks group and GGCLT group (33, 100, 330 mg/kg), respectively. All experimental groups except normal control group received TAA intraperitoneally (i.p.) injection twice weekly. After two weeks of TAA administration, GGCLT or vehicle was given by orally at GGCLT group or TAA group daily for two weeks. Mice were sacrificed after two or four weeks’ treatment, the liver and serum were collected for histopathology assay, immunohistochemistry, western blot and plasma alanine transaminase (ALT) assay. We demonstrated that GGCLT reduces TAA-induced elevated plasma ALT. Histological examination showed increased hepatocyte degeneration and necrosis in TAA group while GGCLT improved dose-dependently. GGCLT reduces TAA-induced liver inflammation, relative to down-regulation hepatic neutrophil, F4/80 expression, proinflammatory mediator NF-κB, pSTAT3 and PAI-1 protein levels. GGCLT also suppressed protein expressions of α-SMA and PDFGR. This study demonstrated that GGCLT could attenuate TAA-induced hepatic injury, inflammation and fibrosis. We suggest GGCLT could improve chronic liver injury and liver fibrosis.
林威良. "Pharmacokinetics and bioavailability studies of Ma-Shing-Gan-Shyr-Tang in rabbits." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/84429609302743118688.
Full textLo, Cheng Wei, and 羅正威. "Investigation of anti-influenza virus mechanism of MA-XING-GAN-SHI-TANG." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/41697412936549213884.
Full text長庚大學
生物醫學研究所
98
Influenza viruses are major human pathogens that cause serious respiratory tract disease and seasonal transmission. Due to the highly morbidity and mortality of virus infection, effective treatment is required for against influenza viruses. There are currently two classes of anti-influenza drugs. One is M2 ion channel inhibitors (amantadine and rimantadine) and the other is NA inhibitors (oseltamivir and zanamivir). Due to the antigenic drift and shift of influenza viruses, emergence of these two drug-resistant viruses has become prevalent. For this reason, we tried to find out Chinese herb medicines that had been used for the treatment of common cold and cough. In this study, we prove that the prescription, MA-XING-GAN-SHI-TANG (MXGST) has anti-influenza virus activity based on the neutralization assay and cytopathic effect (CPE) analysis. According to time of addition assay, MXGST inhibited virus infection at early stage of viral relication. Pre-incubation of virus particles with MXGST was approved to delay the entry of virus and thus decreased the synthesis of viral proteins, such as NP and M1. Besides, we also proved that virus penetration was suppressed by MXGST rather than virus attachment based on penetration assay and attachment assay. Taken together, we demonstrated that MXGST has anti-influenza virus effect due to the blockade of virus entry.
Shu-hua, Wang, and 王淑華. "The Study of Tang Dynasty Merchant Fiction——Base on “Tai Pin Guan Chi”." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/15647898350432449297.
Full text中國文化大學
中國文學研究所
98
In Tang Dynasty, there were more merchant fictions that appear the life style of merchant, due to the stable society and the blooming economy. The authors were specially focused on the characters of the roles to spread various plot and to develop writing skills. The artistry of Tang Dynasty merchant fictions influences the commercial philology in future age. It is worth to study the mentioned influence. This study divided into six chapters is based on the “Tai Pin Guan Chi” to analysis the artistry and value of Tang Dynasty merchant fictions. The development and maturity of Tang Dynasty merchant fictions reflect the distinguishing feature of the age, and expand the commercial philology in future age. It shows the importance and values of Tang Dynasty merchant fictions.