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1

Glish, Gary L., and David J. Burinsky. "Hybrid mass spectrometers for tandem mass spectrometry." Journal of the American Society for Mass Spectrometry 19, no. 2 (February 2008): 161–72. http://dx.doi.org/10.1016/j.jasms.2007.11.013.

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2

Kumar, Praveen. "Tandem Mass Spectrometry." Journal of Neonatology 19, no. 2 (June 2005): 180–83. http://dx.doi.org/10.1177/0973217920050214.

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3

Busch, Kenneth L., Gary L. Glish, Scott A. McLuckey, and John J. Monaghan. "Mass spectrometry/mass spectrometry: techniques and applications of tandem mass spectrometry." Analytica Chimica Acta 237 (1990): 509. http://dx.doi.org/10.1016/s0003-2670(00)83956-2.

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4

Futrell, Jean H. "Mass spectrometry/mass spectrometry: Techniques and applications of tandem mass spectrometry." Microchemical Journal 41, no. 2 (April 1990): 246–47. http://dx.doi.org/10.1016/0026-265x(90)90124-n.

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5

Moriarty, F. "Mass spectrometry/mass spectrometry. Techniques and applications of tandem mass spectrometry." Environmental Pollution 61, no. 3 (1989): 261. http://dx.doi.org/10.1016/0269-7491(89)90246-7.

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6

Cooks, R. G. "Mass Spectrometry/Mass Spectrometry. Techniques and Applications of Tandem Mass Spectrometry." International Journal of Mass Spectrometry and Ion Processes 93, no. 2 (October 1989): 265–66. http://dx.doi.org/10.1016/0168-1176(89)80103-x.

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7

Tian, Qingguo, and Steven J. Schwartz. "Mass Spectrometry and Tandem Mass Spectrometry of Citrus Limonoids." Analytical Chemistry 75, no. 20 (October 2003): 5451–60. http://dx.doi.org/10.1021/ac030115w.

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8

Shoji, Yuki, Mari Yotsu-Yamashita, Teruo Miyazawa, and Takeshi Yasumoto. "Electrospray Ionization Mass Spectrometry of Tetrodotoxin and Its Analogs: Liquid Chromatography/Mass Spectrometry, Tandem Mass Spectrometry, and Liquid Chromatography/Tandem Mass Spectrometry." Analytical Biochemistry 290, no. 1 (March 2001): 10–17. http://dx.doi.org/10.1006/abio.2000.4953.

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9

Budzikiewicz, H. "Selected reviews on mass spectrometric topics. XXVIII. Tandem mass spectrometry." Mass Spectrometry Reviews 8, no. 2 (March 1989): 119. http://dx.doi.org/10.1002/mas.1280080204.

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10

Pisitkun, Trairak, Jason D. Hoffert, Ming-Jiun Yu, and Mark A. Knepper. "Tandem Mass Spectrometry in Physiology." Physiology 22, no. 6 (December 2007): 390–400. http://dx.doi.org/10.1152/physiol.00025.2007.

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Tandem mass spectrometry coupled to liquid chromatography (LC-MS/MS) allows identification of proteins in a complex mixture without need for protein purification (“shotgun” proteomics). Recent progress in LC-MS/MS-based quantification, phosphoproteomic analysis, and targeted LC-MS/MS using multiple reaction monitoring (MRM) has made LC-MS/MS a powerful tool for the study of cell physiology.
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11

Bartlett, K., and M. Pourfarzam. "Tandem mass spectrometry - The potential." Journal of Inherited Metabolic Disease 22, no. 4 (June 1999): 568–71. http://dx.doi.org/10.1023/a:1005520726774.

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12

Zhang, Yan Victoria, Bin Wei, Yu Zhu, Yanhua Zhang, and Martin H. Bluth. "Liquid Chromatography–Tandem Mass Spectrometry." Clinics in Laboratory Medicine 36, no. 4 (December 2016): 635–61. http://dx.doi.org/10.1016/j.cll.2016.07.001.

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13

McLafferty, Fred W., and I. Jonathan Amster. "Tandem Fourier-transform mass spectrometry." International Journal of Mass Spectrometry and Ion Processes 72, no. 1-2 (October 1986): 85–91. http://dx.doi.org/10.1016/0168-1176(86)85036-4.

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14

Lattimer, R. P., H. Münster, and H. Budzikiewicz. "Tandem mass spectrometry of polyglycols." International Journal of Mass Spectrometry and Ion Processes 90, no. 2 (June 1989): 119–29. http://dx.doi.org/10.1016/0168-1176(89)85002-5.

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15

Plattner, Ronald D., and Richard G. Powell. "Tandem Mass Spectrometry of Maytansinoids." Journal of Natural Products 49, no. 3 (May 1986): 475–82. http://dx.doi.org/10.1021/np50045a016.

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16

Petrovic, Mira, and Damià Barceló. "Liquid chromatography–tandem mass spectrometry." Analytical and Bioanalytical Chemistry 405, no. 18 (May 24, 2013): 5857–58. http://dx.doi.org/10.1007/s00216-013-7018-7.

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17

Cairns, Thomas, and Emil G. Siegmund. "Tandem mass spectrometry of mirex." Rapid Communications in Mass Spectrometry 3, no. 10 (October 1989): 340–41. http://dx.doi.org/10.1002/rcm.1290031005.

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18

de Hoffmann, Edmond. "Tandem mass spectrometry: A primer." Journal of Mass Spectrometry 31, no. 2 (February 1996): 129–37. http://dx.doi.org/10.1002/(sici)1096-9888(199602)31:2<129::aid-jms305>3.0.co;2-t.

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19

Griffiths, W. J., M. Hjertman, J. Wejde, O. Larsson, and J. Sjövall. "Tandem Mass Spectrometry of Geranylgeranylcysteine." Journal of Mass Spectrometry 32, no. 8 (August 1997): 899–903. http://dx.doi.org/10.1002/(sici)1096-9888(199708)32:8<899::aid-jms543>3.0.co;2-6.

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20

Kim, Jin Hyo, Cho-Long Jin, Geun-Hyoung Choi, and Byung-Jun Park. "Sample Preparation Method for Perfluorochemicals with LC-Tandem Mass Spectrometry in Agricultural Water." Korean Journal of Pesticide Science 19, no. 1 (March 31, 2015): 1–4. http://dx.doi.org/10.7585/kjps.2015.19.1.1.

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21

Kaiser, Nathan K., Gordon A. Anderson, and James E. Bruce. "Improved mass accuracy for tandem mass spectrometry." Journal of the American Society for Mass Spectrometry 16, no. 4 (April 2005): 463–70. http://dx.doi.org/10.1016/j.jasms.2004.12.005.

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22

van Agthoven, Maria A., Yuko P. Y. Lam, Peter B. O’Connor, Christian Rolando, and Marc-André Delsuc. "Two-dimensional mass spectrometry: new perspectives for tandem mass spectrometry." European Biophysics Journal 48, no. 3 (March 13, 2019): 213–29. http://dx.doi.org/10.1007/s00249-019-01348-5.

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23

Eryavuz Onmaz, Duygu, Fatma Hümryra Yerlikaya, and Mustafa Onmaz. "Molnupiravir detection by tandem mass spectrometry." Archives of Current Medical Research 5, no. 2 (May 31, 2024): 66–74. http://dx.doi.org/10.47482/acmr.1397265.

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Background: After the COVID-19 epidemic that broke out in 2019, studies on antiviral drugs accelerated. In clinical studies with both re-purposed drugs and newly discovered drugs, the need for reliable methods that allow the measurement of drug levels in the blood has increased. Molnupiravir is one of the drugs considered under the treatment of COVID-19 and is on the agenda with conflicting findings. However, there are limited validated methods that report the measurement of molnupiravir levels. Therefore, our aim in this study was to develop a practical, robust validated tandem mass spectrometric method that allows the measurement of molnupiravir levels. Methods: Method development studies for the measurement of molnupiravir levels were performed with a liquid chromatography-tandem mass spectrometry (LC-MS / MS) device and the method was validated according to CLSI (The Clinical &amp; Laboratory Standards Institute) protocols. Linearity, recovery, precision, stability, matrix effect, carry-over and lower limit determination studies were performed. Results: The method was linear with a correlation coefficient value of 0.993 in the range of 20 ng/mL-20 µg/mL. The sensitivity of the method was 20 ng/mL. The CV% obtained from the intra- and inter-assay studies was below 6.2% and the mean recovery was over 95%. Total analysis time was 5 minutes for each sample. Conclusions: A simple, cost-effective, reliable tandem mass spectrometric method with high sensitivity and accuracy based on protein precipitation alone has been developed for the measurement of molnupiravir levels.
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24

Kataev, S. S., O. N. Dvorskaya, M. A. Gofenberg, A. V. Labutin, and A. B. Melentyev. "ANALYTICAL FEATURES OF SYNTHETIC MDMB(N)-073F CANNABIMIMETICS AND ITS MARKERS IN BIOLOGICAL MATERIAL." Pharmacy & Pharmacology 7, no. 4 (September 10, 2019): 184–97. http://dx.doi.org/10.19163/2307-9266-2019-7-4-184-197.

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The aim of the research is to study both analytical features of synthetic MDMB(N)-073F cannabimimetics of indazole carboxamides group by gas chromatography methods combined with tandem mass spectrometry (GC-MS) and high performance liquid chromatography with high-resolution mass spectrometry (HPLC-HRMS) as well as characteristics of the major MDMB(N)-073F metabolite, its glucuronide and derivatives, using gas chromatography with mass-spectrometric (GC-MS) detection and high-performance liquid chromatography (HPLC) with MS/MS mass spectrometry (HPLC-MS/MS) in urine samples to be applied in expert practice, chemical-toxicological and forensic and chemical analyses.Materials and methods. To carry out the study, the following materials were used: plant-based objects with narcotic drugs withdrawn from illegal trafficking and applied to them;. urine samples to be studied under chemical-toxicological and forensic and chemical analyses. For solid-phase epitaxy, SampliQ EVIDEX TFE cartridges – 200 mg – 3 ml (Agilent, USA) were used for sample preparation; β-glucuronidase, Type HP-2, From Helix Pomatia, 100000 UA/ml (Sigma-ALDRICH CHEMI, Germany) was used for enzymatic hydrolysis. GC-MS/MS analysis was made using Agilent 7890 gas chromatograph with a tandem quadrupolar mass-spectrometer Agilent 7000 (Agilent, США); GC-MS analysis was carrid out using gas chromatograph Agilent 7820 with mass-selective detector Agilent 5975 (Agilent, USA); HPLC-HRMS research was made on liquid chromatograph Agilent 1260 with tandem hybrid high-resolution quadrupole-time-of-flight detector Agilent 6540 (Agilent, США); liquid chromatograph Agilent 1260 with Agilent 6460 (Agilent, USA) with tandem mass-spectrometer were used for making HPLC-MS/MS research.Results. The structure of MDMB(N)-073F compound has been confirmed and an exact mass of the protonated molecule corresponding to the chemical formula C19H27FN3O3 fixed by GC-MS/MS and HPLC-HRMS methods. Spectral characteristics of MDMB(N)-073F have been given. One of the branches in MDMB(N)-073F biotransformation in the human body found out by GC-MS and HPLC-MS/MS methods, is the ester decomposition with further conjugation of the resulting acid. The product interacting with glucuronic acid, is found to be the conjugate of major MDMB(N)-073F metabolite of the Ist phase in biotransformation. Metabolites appearing due to the ester decomposition and its conjugate with glucuronic acid, are recommended to be used as markers for synthetic MDMB(N)-073F cannabimimetics in the analysis by chromatographic methods; they can be used for regular screening of biological samples.Conclusion. The research results presented here, are the following: the analytical features characteristic for synthetic MDMB(N)-073F cannabimimetics found out by gas chromatography methods combined with tandem mass spectrometry (GC-MS/ MS) and liquid chromatography of hybrid high-resolution quadrupole-time-of-flight mass spectrometry (HPLC-HRMS), as well as characteristics of major MDMB(N)-073F metabolite, its glucuronide and derivatives with the use of gas chromatography with mass-spectrometric detection (GC-MS) and liquid chromatography combined with tandem mass spectrometry (HPLC-MS/MS) in urine samples to be applied in expert practice, chemical-toxicological, forensic and chemical analyses.
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25

Glish, Gary L. "Multiple stage mass spectrometry: the next generation tandem mass spectrometry experiment." Analyst 119, no. 4 (1994): 533. http://dx.doi.org/10.1039/an9941900533.

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26

Plattner, Ronald D., Marian N. Beremand, and Richard G. Powell. "Analysis of trichothecene mycotoxins by mass spectrometry and tandem mass spectrometry." Tetrahedron 45, no. 8 (January 1989): 2251–62. http://dx.doi.org/10.1016/s0040-4020(01)83430-x.

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27

Raith, Klaus, and Reinhard H. H. Neubert. "Liquid chromatography–electrospray mass spectrometry and tandem mass spectrometry of ceramides." Analytica Chimica Acta 403, no. 1-2 (January 2000): 295–303. http://dx.doi.org/10.1016/s0003-2670(99)00661-3.

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28

Wright, Larry G., R. G. Cooks, and Karl V. Wood. "Matrix enhanced laser desorption in mass spectrometry and tandem mass spectrometry." Biological Mass Spectrometry 12, no. 4 (April 1985): 159–62. http://dx.doi.org/10.1002/bms.1200120404.

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29

Monaghan, J. J., W. E. Morden, T. Johnson, I. D. Wilson, and P. Martin. "Thin layer chromatography/mass spectrometry: The advantages of tandem mass spectrometry." Rapid Communications in Mass Spectrometry 6, no. 10 (October 1992): 608–15. http://dx.doi.org/10.1002/rcm.1290061005.

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30

Pittenauer, Ernst, Günter Allmaier, Erich R. Schmid, Wolfgang Stanek, and Gottfried Heinisch. "Electron impact ionization mass spectrometry and tandem mass spectrometry of phenylalkylpyridazines." Organic Mass Spectrometry 26, no. 6 (June 1991): 595–600. http://dx.doi.org/10.1002/oms.1210260611.

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31

WU, Z., X. XU, S. LUO, D. FANG, and G. ZHANG. "Electrospray Mass Spectrometry and Tandem Mass Spectrometry of Bimetallic Oxovanadium Complexes." Journal of the American Society for Mass Spectrometry 19, no. 9 (September 2008): 1247–54. http://dx.doi.org/10.1016/j.jasms.2008.06.003.

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32

Helleur, R. J., and Pierre Thibault. "Optimization of pyrolysis–desorption chemical ionization mass spectrometry and tandem mass spectrometry of polysaccharides." Canadian Journal of Chemistry 72, no. 2 (February 1, 1994): 345–51. http://dx.doi.org/10.1139/v94-053.

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The operating conditions for pyrolysis–desorption ammonia chemical ionization mass spectrometry and tandem mass spectrometry have been optimized and the technique evaluated for the production and analysis of structurally-informative pyrolytic fragmentation ions corresponding to intact anhydrohexose oligosaccharides, using amylose as the model polysaccharide. Among the various parameters examined it was found that the nature of the solvent used to adhere the sample to the emitter coil and the configuration of the emitter and the rate at which it is heated all play important roles in determining the efficiency of the pyrolytic process and the production of high mass fragment ions. Adjustment of reagent gas pressure together with source temperature also influence the chemical integrity of high mass oligomeric pyrolysis products. Under optimal operating conditions using ammonia reagent gas, the analyses of cellulose, laminarin, agars, and chitin gave relatively abundant ions corresponding to ammonium (or protonated) adducts of up to anhydrohexose tetrasaccharide. More importantly, the generation of such higher mass fragment ions provided a sustained ionic current of sufficient duration to perform tandem mass spectrometric analyses.
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33

Soldin, Steven J., and Offie P. Soldin. "Steroid Hormone Analysis by Tandem Mass Spectrometry." Clinical Chemistry 55, no. 6 (June 1, 2009): 1061–66. http://dx.doi.org/10.1373/clinchem.2007.100008.

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Abstract Background: New high-performance liquid chromatography/tandem mass spectrometry (LC-MS/MS) methods are among the most successful approaches to improve specificity problems inherent in many immunoassays. Content: We emphasize problems with immunoassays for the measurement of steroids and review the emerging role of LC-MS/MS in the measurement of clinically relevant steroids. The latest generation of tandem mass spectrometers has superior limits of quantification, permitting omission of previously employed derivatization steps. The measurement of steroid profiles in the diagnosis and treatment of congenital adrenal hyperplasia, adrenal insufficiency, chronic pelvic pain and prostatitis, oncology (breast cancer), and athletes has important new applications. Conclusions: LC-MS/MS now affords the specificity, imprecision, and limits of quantification necessary for the reliable measurement of steroids in human fluids, enhancing diagnostic capabilities, particularly when steroid profiles are available.
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34

Enns, G. M. "Newborn Screening by Tandem Mass Spectrometry." NeoReviews 2, no. 8 (August 1, 2001): 201e—207. http://dx.doi.org/10.1542/neo.2-8-e201.

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35

Cowan, Tina M. "Neonatal Screening by Tandem Mass Spectrometry." NeoReviews 6, no. 12 (December 2005): e539-e548. http://dx.doi.org/10.1542/neo.6-12-e539.

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36

Matern, Dietrich. "Tandem Mass Spectrometry in Newborn Screening." Endocrinologist 12, no. 1 (January 2002): 50–57. http://dx.doi.org/10.1097/00019616-200201000-00011.

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37

Banta-Wright, Sandra A., and Robert D. Steiner. "Tandem Mass Spectrometry in Newborn Screening." Journal of Perinatal & Neonatal Nursing 18, no. 1 (January 2004): 41–60. http://dx.doi.org/10.1097/00005237-200401000-00005.

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38

Pollitt, RJ. "Tandem mass spectrometry screening: proving effectiveness." Acta Paediatrica 88 (January 2, 2007): 40–44. http://dx.doi.org/10.1111/j.1651-2227.1999.tb01155.x.

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39

Chen, Wen-Ling, Tzu-Fang Hsu, and Chia-Yang Chen. "Performance Liquid Chromatography/Tandem Mass Spectrometry." Journal of AOAC INTERNATIONAL 94, no. 3 (May 1, 2011): 872–77. http://dx.doi.org/10.1093/jaoac/94.3.872.

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Abstract A sensitive method was developed using ultra-high-performance liquid chromatography (UHPLC)/MS/MS with positive electrospray ionization for determining aflatoxin M1 (AFM1) in milk and milk powder. A 50 mL quantity of low-fat liquid milk containing 100 ng/L AFM1 was prepared using immunoaffinity columns with a mean recovery rate of 79% (n = 3). UHPLC columns (BEH C18, BEH HILIC, and HSS T3) greatly reduced the chromatographic time and lowered the instrumental detection limits (IDLs) 16 to 58 times compared to an HPLC column (Betabasic C18). The HSS T3 column was chosen because it provided a low IDL (0.11 pg) and the lowest ion suppression of signal intensity (63.4%) among the tested columns. Matrix-fortified calibration curves were used for quantification and showed good linearity (r &gt; 0.997) at 0.05–500 ng/mL. The LOD was 0.18 ng/kg for milk and 2.08 ng/kg for milk powder, based on the signal intensity of the confirmatory product ion (m/z 259.1), which was less abundant than the quantitative product ion (m/z 273.1). Certified reference materials of milk powder
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40

Sweetman, Lawrence. "Newborn Screening by Tandem Mass Spectrometry." Clinical Chemistry 47, no. 11 (November 1, 2001): 1937–38. http://dx.doi.org/10.1093/clinchem/47.11.1937.

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41

Hunt, D. F., J. R. Yates, J. Shabanowitz, S. Winston, and C. R. Hauer. "Protein sequencing by tandem mass spectrometry." Proceedings of the National Academy of Sciences 83, no. 17 (September 1, 1986): 6233–37. http://dx.doi.org/10.1073/pnas.83.17.6233.

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42

Li, Hui-Jing, and Max L. Deinzer. "Tandem Mass Spectrometry for Sequencing Proanthocyanidins." Analytical Chemistry 79, no. 4 (February 2007): 1739–48. http://dx.doi.org/10.1021/ac061823v.

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43

Lehmann, Wolf D. "New uses for tandem mass spectrometry." Trends in Biotechnology 19, no. 6 (June 2001): 238. http://dx.doi.org/10.1016/s0167-7799(01)01638-9.

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44

Cui, Zheng, and Michael J. Thomas. "Phospholipid profiling by tandem mass spectrometry." Journal of Chromatography B 877, no. 26 (September 2009): 2709–15. http://dx.doi.org/10.1016/j.jchromb.2009.06.034.

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45

Johnson, Jodie V., and Richard A. Yost. "Tandem Mass Spectrometry for Trace Analysis." Analytical Chemistry 57, no. 7 (June 1985): 758A—768A. http://dx.doi.org/10.1021/ac00284a718.

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46

&NA;. "TANDEM MASS SPECTROMETRY IN NEWBORN SCREENING." Advances in Neonatal Care 3, no. 6 (December 2003): 257. http://dx.doi.org/10.1016/j.adnc.2003.11.007.

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47

Avard, Denise, Hilary Vallance, Cheryl Greenberg, and Beth Potter. "Newborn Screening by Tandem Mass Spectrometry." Canadian Journal of Public Health 98, no. 4 (July 2007): 284–86. http://dx.doi.org/10.1007/bf03405404.

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48

Taguchi, Ryo, Toshiaki Houjou, Hiroki Nakanishi, Toshiyuki Yamazaki, Mayuko Ishida, Masayoshi Imagawa, and Takao Shimizu. "Focused lipidomics by tandem mass spectrometry." Journal of Chromatography B 823, no. 1 (August 2005): 26–36. http://dx.doi.org/10.1016/j.jchromb.2005.06.005.

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49

Lau, Tai-Chu, Jiangyao Wang, Roger Guevremont, and K. W. Michael Siu. "Electrospray tandem mass spectrometry of polyoxoanions." Journal of the Chemical Society, Chemical Communications, no. 8 (1995): 877. http://dx.doi.org/10.1039/c39950000877.

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50

Zubarev, R. A., M. L. Nielsen, and B. A. Budnik. "Tandem Ionization Mass Spectrometry of Biomolecules." European Journal of Mass Spectrometry 6, no. 3 (June 2000): 235–40. http://dx.doi.org/10.1255/ejms.351.

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