Academic literature on the topic 'T385'

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Journal articles on the topic "T385"

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Albiach-Martí, María R., Munir Mawassi, Siddarame Gowda, Tatineni Satyanarayana, Mark E. Hilf, Savita Shanker, Ernesto C. Almira, et al. "Sequences of Citrus Tristeza VirusSeparated in Time and Space Are Essentially Identical." Journal of Virology 74, no. 15 (August 1, 2000): 6856–65. http://dx.doi.org/10.1128/jvi.74.15.6856-6865.2000.

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ABSTRACT The first Citrus tristeza virus (CTV) genomes completely sequenced (19.3-kb positive-sense RNA), from four biologically distinct isolates, are unexpectedly divergent in nucleotide sequence (up to 60% divergence). Understanding of whether these large sequence differences resulted from recent evolution is important for the design of disease management strategies, particularly the use of genetically engineered mild (essentially symptomless)-strain cross protection and RNA-mediated transgenic resistance. The complete sequence of a mild isolate (T30) which has been endemic in Florida for about a century was found to be nearly identical to the genomic sequence of a mild isolate (T385) from Spain. Moreover, samples of sequences of other isolates from distinct geographic locations, maintained in different citrus hosts and also separated in time (B252 from Taiwan, B272 from Colombia, and B354 from California), were nearly identical to the T30 sequence. The sequence differences between these isolates were within or near the range of variability of the T30 population. A possible explanation for these results is that the parents of isolates T30, T385, B252, B272, and B354 have a common origin, probably Asia, and have changed little since they were dispersed throughout the world by the movement of citrus. Considering that the nucleotide divergence among the other known CTV genomes is much greater than those expected for strains of the same virus, the remarkable similarity of these five isolates indicates a high degree of evolutionary stasis in some CTV populations.
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Martín, Susana, Adrián Sambade, Luis Rubio, María C. Vives, Patricia Moya, José Guerri, Santiago F. Elena, and Pedro Moreno. "Contribution of recombination and selection to molecular evolution of Citrus tristeza virus." Journal of General Virology 90, no. 6 (June 1, 2009): 1527–38. http://dx.doi.org/10.1099/vir.0.008193-0.

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The genetic variation of Citrus tristeza virus (CTV) was analysed by comparing the predominant sequence variants in seven genomic regions (p33, p65, p61, p18, p13, p20 and p23) of 18 pathogenically distinct isolates from seven different countries. Analyses of the selective constraints acting on each codon suggest that most regions were under purifying selection. Phylogenetic analysis shows diverse patterns of molecular evolution for different genomic regions. A first clade composed of isolates that are genetically close to the reference mild isolates T385 or T30 was inferred from all genomic regions. A second clade, mostly comprising virulent isolates, was defined from regions p33, p65, p13 and p23. For regions p65, p61, p18, p13 and p23, a third clade that mostly included South American isolates could not be related to any reference genotype. Phylogenetic relationships among isolates did not reflect their geographical origin, suggesting significant gene flow between geographically distant areas. Incongruent phylogenetic trees for different genomic regions suggested recombination events, an extreme that was supported by several recombination-detecting methods. A phylogenetic network incorporating the effect of recombination showed an explosive radiation pattern for the evolution of some isolates and also grouped isolates by virulence. Taken together, the above results suggest that negative selection, gene flow, sequence recombination and virulence may be important factors driving CTV evolution.
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Keiser, Stefanie, Daniela Flück, Fabienne Hüppin, Alexander Stravs, Matthias P. Hilty, and Carsten Lundby. "Heat training increases exercise capacity in hot but not in temperate conditions: a mechanistic counter-balanced cross-over study." American Journal of Physiology-Heart and Circulatory Physiology 309, no. 5 (September 2015): H750—H761. http://dx.doi.org/10.1152/ajpheart.00138.2015.

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The aim was to determine the mechanisms facilitating exercise performance in hot conditions following heat training. In a counter-balanced order, seven males (V̇o2max 61.2 ± 4.4 ml·min−1·kg−1) were assigned to either 10 days of 90-min exercise training in 18 or 38°C ambient temperature (30% relative humidity) applying a cross-over design. Participants were tested for V̇o2max and 30-min time trial performance in 18 (T18) and 38°C (T38) before and after training. Blood volume parameters, sweat output, cardiac output (Q̇), cerebral perfusion (i.e., middle cerebral artery velocity [MCAvmean]), and other variables were determined. Before one set of exercise tests in T38, blood volume was acutely expanded by 538 ± 16 ml with an albumin solution (T38A) to determine the role of acclimatization induced hypervolemia on exercise performance. We furthermore hypothesized that heat training would restore MCAvmean and thereby limit centrally mediated fatigue. V̇o2max and time trial performance were equally reduced in T38 and T38A (7.2 ± 1.6 and 9.3 ± 2.5% for V̇o2max; 12.8 ± 2.8 and 12.9 ± 2.8% for time trial). Following heat training both were increased in T38 (9.6 ± 2.1 and 10.4 ± 3.1%, respectively), whereas both V̇o2max and time trial performance remained unchanged in T18. As expected, heat training augmented plasma volume (6 ± 2%) and mean sweat output (26 ± 6%), whereas sweat [Na+] became reduced by 19 ± 7%. In T38 Q̇max remained unchanged before (21.3 ± 0.6 l/min) to after (21.7 ± 0.5 l/min) training, whereas MCAvmean was increased by 13 ± 10%. However, none of the observed adaptations correlated with the concomitant observed changes in exercise performance.
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Schäfer, Axel Georg Meender, Britta Sebelin, and Lena Spitzer. "Cultural adaption and validation of the German version of the diagnostic thinking inventory (DTI-G) / Ein Instrument zur Erhebung diagnostischer Kompetenz: Validierung und kulturelle Adaptation des Diagnostic Thinking Inventory (DTI-G)." International Journal of Health Professions 6, no. 1 (March 13, 2019): 32–45. http://dx.doi.org/10.2478/ijhp-2019-0002.

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Abstract Diagnostic ability is essential for expert professional practice. Several instruments have been developed to assess diagnostic skills independent of specific knowledge. One such instrument is the diagnostic thinking inventory (DTI), which is used in different settings to evaluate diagnostic performance and has shown acceptable reliability and validity. The aim of the present study was to translate and validate a German version (DTI-G). Cultural adaptation and translation were performed according to international guidelines. Internal consistency and item discrimination indexes were calculated. The factorial structure of the DTI-G, test-retest reliability and known-groups validity were tested. A total of 388 physiotherapists completed the questionnaire. The internal consistency was good for the overall score of the DTI-G (Cronbach’s a = 0.84). Exploratory factor analysis yielded a five-factor solution with 21 items that explained 55% of the total variance across items. A confirmatory principal component analysis resulted in the same five-factor structure, showing an acceptable to good overall fit of the model (CFI = 0.93; RMSEA = 0.05; SRMR = 0.06). Test-retest reliability was found to be good (intraclass correlation coefficient ICC2,1 = 0.87, p < 0.001, n = 118). The difference between participants with more than 9 years of clinical experience and those with less than 9 years of clinical experience (median split) was significant (t385 = 6.00, p < 0.001), supporting known-groups validity. The results support construct validity and indicate good test-retest reliability of the DTI-G. The DTI-G can be used to measure and develop diagnostic ability of physiotherapists in clinical practice and education. Further research is necessary to validate the questionnaire for other health professions.
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Osabe, Makoto, and Masahiko Negishi. "Active ERK1/2 Protein Interacts with the Phosphorylated Nuclear Constitutive Active/Androstane Receptor (CAR; NR1I3), Repressing Dephosphorylation and Sequestering CAR in the Cytoplasm." Journal of Biological Chemistry 286, no. 41 (August 26, 2011): 35763–69. http://dx.doi.org/10.1074/jbc.m111.284596.

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The nuclear constitutive active/androstane receptor (CAR) is inactivated and sequestered in the cytoplasm when Thr-38 is phosphorylated. Here, we have demonstrated that activated ERK1/2 interacts with phosphorylated CAR to repress dephosphorylation of Thr-38. The phosphorylation-dependent interaction between CAR and ERK1/2 was examined by co-immunoprecipitation experiments of ectopically expressed FLAG-tagged CAR T38A and CAR T38D mutants with endogenous phospho-ERK1/2 in Huh-7 cells. Phospho-ERK1/2 coprecipitated only the phosphorylation-mimicking CAR T38D mutant; this coprecipitation was mediated by the interaction with the xenochemical response signal peptide near the C terminus of CAR. This interaction increased after EGF treatment and decreased after treatment with the MEK inhibitor U0126 as well as after knockdown of MEK1/2 by shRNA in Huh-7 cells. The phosphorylation levels of Thr-38 of CAR decreased in U0126-treated Huh-7 cells. Thus, activated ERK1/2 interacts with CAR and represses dephosphorylation of Thr-38, providing a cell signal-regulated mechanism for CAR activation.
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Casteleti de Souza, João Paulo, Ciro Winckler, Luiz Gustavo Santos, Thiago Fernando Lourenço, and Miguel Arruda. "Vertical jump performance in athletes with cerebral palsy." Retos 56 (April 26, 2024): 162–66. http://dx.doi.org/10.47197/retos.v56.102742.

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The principal difference between an Olympic and a Paralympic sport is the classification structure of the sports in which the athlete competes. The Paralympic Classification System subsidizes such a structure. This study aimed to investigate possible height differences in six vertical jumps in Para athletics athletes with cerebral palsy from classes T35 to T38 to contribute to the Paralympic Classification System. They participated in this study, and forty-one athletes were divided into the experimental group (thirty-five with cerebral palsy T35= 6; T36= 10; T37 = 12; T38 = 7) and the Control Group. The athletes were evaluated using the OptoJump Next equipment (OJ). The protocol sequence of the Vertical Jump battery included squat jump, single left leg one jump, single right leg one jump, both leg seven jumps, single left leg seven jumps, and single right leg seven jumps. We found significant differences between all classes and the control group (p<0.001). This study indicates that the battery of vertical jump tests not only identifies the athletes' eligibility but also helps to allocate different classes of athletes with cerebral palsy. To develop a technical assessment that contributes to implementing evidence to the Classification System of World Paralympic Athletics - WPA. Keywords: Para athletics; evidence-based classification, jump test, and cerebral palsy.
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Vazquez, Francisca, Shivapriya Ramaswamy, Noriaki Nakamura, and William R. Sellers. "Phosphorylation of the PTEN Tail Regulates Protein Stability and Function." Molecular and Cellular Biology 20, no. 14 (July 15, 2000): 5010–18. http://dx.doi.org/10.1128/mcb.20.14.5010-5018.2000.

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ABSTRACT The PTEN gene is a tumor suppressor localized in the frequently altered chromosomal region 10q23. The tumor suppressor function of the PTEN protein (PTEN) has been linked to its ability to dephosphorylate the lipid second-messenger phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,4-bisphosphate and, by doing so, to antagonize the phosphoinositide 3-kinase pathway. The PTEN protein consists of an amino-terminal phosphatase domain, a lipid binding C2 domain, and a 50-amino-acid C-terminal domain (the “tail”) of unknown function. A number of studies have shown that the tail is dispensable for both phosphatase activity and blocking cell growth. Here, we show that the PTEN tail is necessary for maintaining protein stability and that it also acts to inhibit PTEN function. Thus, removing the tail results in a loss of stability but does not result in a loss of function because the resultant protein is more active. Furthermore, tail-dependent regulation of stability and activity is linked to the phosphorylation of three residues (S380, T382, and T383) within the tail. Therefore, the tail is likely to mediate the regulation of PTEN function through phosphorylation.
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Kisseljov, F., S. Vinokurova, N. Kisseljova, L. Pavlova, M. Fedorova, A. Katargin, A. Petrenko, and L. Korolenkova. "T35." European Journal of Cancer Supplements 13, no. 1 (November 2015): 25. http://dx.doi.org/10.1016/j.ejcsup.2015.08.044.

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Huang, Z., X. Huang, Y. Huang, Z. Li, Q. Huang, and T. Li. "POS0044 T315 SUPPRESSES OSTEOGENIC DIFFERENTIATION IN SAOS-2 CELLS BY INHIBITING PHOSPHORYLATION OF AKT." Annals of the Rheumatic Diseases 80, Suppl 1 (May 19, 2021): 227.1–227. http://dx.doi.org/10.1136/annrheumdis-2021-eular.2428.

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Background:New bone formation is common in the late stage of various inflammatory arthritis, while osteoblasts play a vital role in this process. Activation of PI3K/ Akt pathway promotes the differentiation and enhances the function of osteoblasts [1]. T315 is a novel small molecule drug, which may induce apoptosis and suppress the expression of cellular markers of chronic lymphocytic leukemia cells by disrupting PI3K/ Akt pathway [2]. However, the lack of study focuses on the influence of T31T on the other cells, except tumor cell lines.Objectives:We aimed to assess the effect of T315 on human osteoblast-like Saos-2 cells, while its potential mechanism in PI3K/ Akt pathway was evaluated as well.Methods:(1) Saos-2 was stimulated with an osteogenic reagent which contained L-ascorbic acid, β-glycerophosphoric acid, and dexamethasone. The concentration of T315 was adjusted to 0μg/ml, 1μg/ml, and 2μg/ml in the culture medium. (2) Alizarin red stain and alkaline phosphatase (ALP) stain were performed at d0, d7, d14, and d21 after being treated with T315. (3) Cellular protein was extracted at d0, d3, and d6 after being treated with T315, then ALP activity was tested based on a recommendation from the manufacturer of the kit. (4) Collagen type 1α2 Chain (Col1α2) and osteocalcin (OCN), two osteogenic markers, were measured through western blot, with glyceraldehyde 3-phosphate dehydrogenase (GAPDH) as an endogenous control. (5) Phospho-phosphoinositide 3-kinase (pPI3K), phospho-protein kinase B (pAkt), and runt-related transcription factor 2 (Runx2) was tested through western blot as well. GAPDH or protein kinase (Akt) was chosen as an internal reference as appropriate. (6) Analysis of variance with the least significant difference was used to analyze the data. A P<0.05 was considered statistically significant.Results:(1) The higher concentration of T315 related to the less relative mineralized area and the positive area of ALP, while longer incubation time with T315 decreased these regions as well (Figure 1A-C). (2) T315 reduced the activity of ALP accordingly (Figure 1D). (3) T315 suppressed the protein expression of Col1α2 and OCN in a dose-dependent and time-dependent manner (Figure 1E, F). (4) T315 did not alter pPI3K, but it inhibited the phosphorylation of Akt (Figure 1G, H). (5) Runx2 was reduced because of the greater dose or longer incubation time with T315 (Figure 1).Conclusion:T315 inhibits the differentiation of osteoblasts through inhibiting the phosphorylation of Akt. Surprisingly, pPI3K seldom changes in this process, so its detail mechanism should be investigated in further.References:[1]Exp Biol Med (Maywood) 2020;245(6):552-561.[2]Blood 2015;125(2):284-295.Figure 1.Effect of T315 on Saos-2 cells and PI3K/Akt pathway. (A) Alizarin red stain and ALP stain at d21. (B) Relative mineralized area in Alizarin red stain. (C) Positive area in ALP stain. (D) ALP activity. Western blot analysis and its bands at d6 for Col1α2 (E), OCN (F), pPI3K (G), pAkt (H), and Runx2 (I). Results were normalized by GAPDH or Akt. ALP: Alkaline phosphatase; Col1α2: Collagen type 1α2 Chain; GAPDH: Glyceraldehyde 3-phosphate dehydrogenase; OCN: Osteocalcin; pPI3K: Phospho-phosphoinositide 3-kinase; pAkt: Phospho-protein kinase B; Akt: Protein kinase; Runx2: Runt-related transcription factor 2. a Compared with d3 in the same concentration of T315, P<0.05. b Compared with d0 in the same concentration of T315, P<0.05. c Compared with 1μg/ml T315 in the same incubation time, P<0.05. d Compared with 2μg/ml T315 in the same incubation time, P<0.05.Disclosure of Interests:None declared.
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Gómez-Miranda, Luis Mario, Daniel Rojas-Valverde, Carlos Gómez-Carmona, Juan José Calleja-Núñez, Héctor Reynaldo Triana-Reina, and Alejandro Rodríguez-Montero. "Agreement, reliability, predictors and classification proposal of a 15´-time trial test to assess critical power in amateur swimmers." Retos 51 (December 4, 2023): 1381–87. http://dx.doi.org/10.47197/retos.v51.98026.

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This study aimed to explore the agreement and reliability of a 15´-time trial test (T315´) to assess critical power in a large cohort of amateur swimmers. An observational retrospective cohort study total of 2212 amateur swimmers were made evaluating the results of anthropometry, cardiovascular and functional fitness assessments. Also, the participants performed a front crawl swimming 15´all-out test to assess critical power. The Kolmogorov-Smirnov, t-test, regression, percentiles, intraclass correlation coefficient and Cohen’s d effect size were developed using a statistical software A T315´ categorization proposal was made based on sex and age. There were differences by sex in all anthropometric, functional, physiological and T315´ outcomes. The T315´ swimming test obtained almost perfect reliability in the distance based on intraclass correlation values and linear correlation coefficients. A bias of T315´ of 2% was found, which represented a total of 10.65m between tests. T315´ is a useful test to assess critical power as a baseline fitness reference value for programming swimming exercises in amateurs. Keywords: anaerobic capacity, aerobic capacity, swimming, critical speed, evaluation, assessment.
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Dissertations / Theses on the topic "T385"

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Pharasi, Bhuwan. "Murray polygons as a tool in image processing." Thesis, University of St Andrews, 1990. http://hdl.handle.net/10023/13580.

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This thesis reports on some applications of murray polygons, which are a generalization of space filling curves and of Peano polygons in particular, to process digital image data. Murray techniques have been used on 2-dimensional and 3-dimensional images, which are in cartesian/polar co-ordinates. Attempts have been made to resolve many associated aspects of image processing, such as connected components labelling, hidden surface removal, scaling, shading, set operations, smoothing, superimposition of images, and scan conversion. Initially different techniques which involve quadtree, octree, and linear run length encoding, for processing images are reviewed. Several image processing problems which are solved using different techniques are described in detail. The steps of the development from Peano polygons via multiple radix arithmetic to murray polygons is described. The outline of a software implementation of the basic and fast algorithms are given and some hints for a hardware implementation are described The application of murray polygons to scan arbitrary images is explained. The use of murray run length encodings to resolve some image processing problems is described. The problem of finding connected components, scaling an image, hidden surface removal, shading, set operations, superimposition of images, and scan conversion are discussed. Most of the operations described in this work are on murray run lengths. Some operations on the images themselves are explained. The results obtained by using murray scan techniques are compared with those obtained by using standard methods such as linear scans, quadtrees, and octrees. All the algorithms obtained using murray scan techniques are finally presented in a menu format work bench. Algorithms are coded in PS-algol and the C language.
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Taylor, Mark W. "Special finite elements for modelling adhesively bonded joints in two- and three-dimensions." Thesis, This resource online, 1995. http://scholar.lib.vt.edu/theses/available/etd-12232009-020637/.

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Tate, Deborah F. "Promoting exercise adoption through computer networks." Thesis, This resource online, 1995. http://scholar.lib.vt.edu/theses/available/etd-12232009-020633/.

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Tappert, Peter M. "Damage identification using inductive learning." Thesis, This resource online, 1994. http://scholar.lib.vt.edu/theses/available/etd-05092009-040651/.

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Tavenner, Cloyd Tallman. "FAIRSHARE:an investigation into driving a pay for performance system with the multi-criteria measurement technique." Master's thesis, Virginia Tech, 1991. http://hdl.handle.net/10919/40609.

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Liu, Ta-Ming. "Kinase Targeting Therapies in Chronic Lymphocytic Leukemia: Mechanisms of Acquired Ibrutinib Resistance and the Pre-Clinical Development of OSU-T315." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1404917090.

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Tatarka, Bernadette. "Relationships among body-self relations, exercise involvement, and exercise clothing attitude for women in regular exercise programs." Diss., This resource online, 1995. http://scholar.lib.vt.edu/theses/available/etd-06062008-162917/.

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Taylor, Delana. "Cytoskeletal changes in SY5Y neuroblastoma cells exposed to acrylamide : an immunocytochemical study /." Thesis, This resource online, 1994. http://scholar.lib.vt.edu/theses/available/etd-07102009-040505/.

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Tabisz, Wojciech Antoni. "High-frequency multi-resonant power conversion techniques." Diss., Virginia Tech, 1990. http://hdl.handle.net/10919/37404.

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Tankel, Jesslyn Elise. "A Teaching Toy: Free Forms in an Abstract Landscape." Thesis, Virginia Tech, 1998. http://hdl.handle.net/10919/45220.

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As a young student, I enjoyed a passion for the studio arts and an interest in art history. I ardently pursued these areas in college, continuing their exploration in graduate school in the field of Industrial Design. For the thesis project, my objective is to foster in children an appreciation for art and, possibly, to help them develop a critical and appreciative eye toward their environment. In my research, I find inspiration in child psychology and the toys of child's play, in 15th-century Islamic art and 20th-century Abstraction, and in naturally occurring events such as ivy twisting up a knotty tree trunk and soft ripples in a pond. The assimilation of these elements, together with the ideas that they generate, evolve into the foundation for my project. My intent is to design a toy which provides children ages six to twelve years with insight into both the world of nature and the realm of art. Further, the toy will heighten each child's visual vocabulary to acknowledge the organic, natural line that exists in nature and which is, perhaps, represented in abstract art. These goals are the guiding principles for my work.
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Books on the topic "T385"

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Rogers, David F. Mathematical elements for computer graphics. 2nd ed. New York: McGraw-Hill, 1990.

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Kate, Binder, ed. Sams teach yourself Adobe Photoshop CS3 in 24 hours. 4th ed. Indianapolis, Ind: Sams Pub., 2007.

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Pauline, Baker M., ed. Computer graphics. 2nd ed. Englewood Cliffs, N.J: Prentice-Hall, 1994.

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Mason, Woo, Woo Mason, and OpenGL Architecture Review Board, eds. OpenGL programming guide: The official guide to learning OpenGL, version 1.2. 3rd ed. Reading, MA: Addison-Wesley, 1999.

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1971-, Ray John, ed. Sams teach yourself Adobe Creative Suite 3 all in one. Indianapolis, Ind: Sams Pub., 2008.

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1967-, Zachmann Gabriel, ed. Geometric data structures for computer graphics. Wellesley, MA: A K Peters, 2005.

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1942-, Foley James D., and Foley James D. 1942-, eds. Computer graphics: Principles and practice. 2nd ed. Reading, Mass: Addison-Wesley, 1990.

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Peter, Lourekas, ed. Photoshop 6 for Windows and Macintosh. Berkeley, Calif: Peachpit, 2001.

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Open University. T395 Course Team., ed. T395 Mechatronics: Designing intelligent machines. [Milton Keynes]: Open University, 2000.

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Rhoda, Grossman, ed. Painter 6 f/x & design. Scottsdale, AZ: Coriolis Group Books, 2000.

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Book chapters on the topic "T385"

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Jai Maruthi, Revanna, Rajeevalochanam Prathapanayaka, and Nanjundaiah Vinod Kumar. "3D Finite Element Vibrational Analysis of T385 Turbine Rotor BLISK Using SAFE Diagram." In Lecture Notes in Mechanical Engineering, 555–67. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-5701-9_45.

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Martín-Ruiz, Susana, Francisco J. Aceituno, and Juan Gutiérrez Soto. "Setting up the T35 Telescope at Sierra Nevada Observatory for Detecting Variable Stars in Open Clusters." In Star Clusters in the Era of Large Surveys, 261–62. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-22113-2_49.

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"T38." In Livy: The Fragments and Periochae, Vol. 1: Fragments, Citations, Testimonia. Oxford University Press, 2023. http://dx.doi.org/10.1093/oseo/instance.00297004.

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"T35." In Livy: The Fragments and Periochae, Vol. 1: Fragments, Citations, Testimonia. Oxford University Press, 2023. http://dx.doi.org/10.1093/oseo/instance.00297001.

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"^#.^t38: TLC of Diuretics." In Thin Layer Chromatography in Drug Analysis, 736–67. CRC Press, 2013. http://dx.doi.org/10.1201/b15637-42.

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"^#.^t35: TLC of Steroids and Analogs." In Thin Layer Chromatography in Drug Analysis, 670–719. CRC Press, 2013. http://dx.doi.org/10.1201/b15637-39.

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Conference papers on the topic "T385"

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Lee, Su-Lin, En-Chi Hsu, Hsiao-Ching Chuang, Samuel Kulp, and Ching-Shih Chen. "Abstract 1360: Design, synthesis, and target validation of T315, a putative ILK inhibitor." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-1360.

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Heise, T., B. Daxl, M. Matthes, S. Zoubaa, S. Haerteis, J. Schwartz, J. Medenbach, S. Corbacioglu, and G. Sommer. "Functional characterization of T389 phosphorylation of RNA-binding protein La in neuroblastoma cells." In 35. Jahrestagung der Kind-Philipp-Stiftung für pädiatrisch onkologische Forschung. Georg Thieme Verlag KG, 2024. http://dx.doi.org/10.1055/s-0044-1786588.

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Devine, Adam, and John Clowes. "Technology Roadmap for Supercontinuum Fiber Lasers." In Workshop on Specialty Optical Fibers and their Applications. Washington, D.C.: OSA, 2013. http://dx.doi.org/10.1364/wsof.2013.t3.5.

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Agarwal, Abhinav, Bhargav Somepalli, Deepa Venkitesh, and Balaji Srinivasan. "Simultaneous Multi-point Sensing based on Brillouin Optical Correlation Domain Analysis with Digital Lock-in Detection Scheme." In Optical Fiber Sensors. Washington, D.C.: OSA, 2021. http://dx.doi.org/10.1364/ofs.2020.t3.5.

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Bhatta, Hari Datta, Roy Davidi, and Moshe Tur. "Frequency scanning interrogators and non-uniform sampling." In Optical Fiber Sensors. Washington, D.C.: OSA, 2021. http://dx.doi.org/10.1364/ofs.2020.t3.85.

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Yu, Yi, Xiubin Gu, Xiaolan Zhao, Edward Chang, Laura Cousens, Carol G. Waghorne, and Thomas C. K. Chan. "Abstract 3948: Identification of phosphorylated NF45 (T388) as a potential pharmacodynamic biomarker for ARQ 501 (β-lapachone)." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-3948.

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Chou, Chih-Chien, Su-Lin Lee, Samuel K. Kulp, and Ching-Shih Chen. "Abstract 3958: T315, a novel integrin-linked kinase inhibitor, suppresses hypoxia-induced epithelial-to-mesenchymal transition in prostate cancer." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-3958.

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Wolfe, James M., and Morgan M. Fanberg. "Statistical Analysis for Shipboard Electrical Power Plant Design." In SNAME Maritime Convention. SNAME, 2013. http://dx.doi.org/10.5957/smc-2013-t38.

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The traditional electric power load analysis (EPLA) uses a very basic routine of assigning demand factors to each connected electric load, then summing these to arrive at an estimated power plant load. This method is overly simplistic, gives a false sense of certainty, and does not accurately reflect vessel operations. This paper will describe an alternative to traditional methods of determining ratings and configurations for electric power plants during vessel concept and preliminary design. This method uses statistical methods to calculate a range of possible power plant demand. Resulting data can be used to evaluate power plant configurations with respect to design risk, vessel operating profiles, and potential limitations. The ability to better evaluate the complete range of required electric power across all operating profiles increases in importance as vessel power plants become more sophisticated with the introduction of variable speed generation, battery/hybrid power systems, DC power distribution, and distributed load centers.
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Steinke, Dean M., Ryan S. Nicoll, Tony Thompson, and Bruce Paterson. "Design Methodology and Numerical Analysis of a Cable Ferry." In SNAME Maritime Convention. SNAME, 2013. http://dx.doi.org/10.5957/smc-2013-t35.

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Cable ferry systems offer many advantages including simplicity, low maintenance, low operations risk, and lower energy use when compared to freely maneuvering ferries. In this paper, a proposed ferry system on a long 2000m crossing is assessed using advanced time domain analysis with verification by model scale tests. The results are used to ensure a safe and reliable design with similar level of service to the incumbent ferry system on the existing route.
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Kim, Booki, Min-Cheol Ryu, Jun-Hyung Jung, and Yungsup Shin. "Identification of Critical Sea States for Sloshing Model Tests." In SNAME Maritime Convention. SNAME, 2010. http://dx.doi.org/10.5957/smc-2010-t38.

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This paper presents a methodology for identifying a set of irregular sea states for sloshing model test conditions that are most likely to produce large sloshing pressures on tank walls. To identify the critical sea states, the sloshing pseudo-response amplitude operator (RAO) is defined based on the total sloshing wave energy that is the sum of kinetic and potential energies on the free surface. The mathematical model is formulated in the frequency domain within the regime of potential flow theory. A concept of sloshing intensity is then introduced to define the sloshing severity in an irregular sea state based on the area under the sloshing wave energy response spectrum curve. The tank is expected to induce violent fluid motions for high sloshing intensity values and, as a result, its walls can experience large sloshing impact pressures. The validity of the proposed methodology is investigated by comparing the results of the numerical analysis to those of the model test for the cargo tank of a floating liquefied natural gas terminal. Favorable results in identifying the critical sea states are obtained for tested filling levels. The proposed methodology can be utilized as a pre-screening procedure for selecting relevant sea states at the initial phase of the sloshing model test and for use in the selection of sloshing flow simulation conditions.
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Reports on the topic "T385"

1

Parsons, G. Real-time Facsimile (T.38) - image/t38 MIME Sub-type Registration. RFC Editor, August 2002. http://dx.doi.org/10.17487/rfc3362.

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Jones, P., and H. Tamura. Real-Time Facsimile (T.38) - audio/t38 MIME Sub-type Registration. RFC Editor, August 2006. http://dx.doi.org/10.17487/rfc4612.

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Michel Jr., Frederick C., Harry A. J. Hoitink, Yitzhak Hadar, and Dror Minz. Microbial Communities Active in Soil-Induced Systemic Plant Disease Resistance. United States Department of Agriculture, January 2005. http://dx.doi.org/10.32747/2005.7586476.bard.

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Induced Systemic Resistance (ISR) is a highly variable property that can be induced by compost amendment of potting media and soils. For example, previous studies showed that only 1 of 79 potting mixes prepared with different batches of mature composts produced from several different types of solid wastes were able to suppress the severity of bacterial leaf spot of radish caused by Xanthomonas campestris pv. armoraciae compared with disease on plants produced in a nonamended sphagnum peat mix. In this project, microbial consortia in the rhizosphere of plants grown in ISR-active compost-amended substrates were characterized. The plants used included primarily cucumber but also tomato and radish. Rhizosphere microbial consortia were characterized using multiple molecular tools including DGGE (Israel) and T -RFLP (Ohio) in both ISR-active field plots and potting media. Universal as well as population-specific bacterial and fungal PCR primers were utilized. T -RFLP analyses using universal bacterial primers showed few significant differences in overall bacterial community composition in ISR-active and inactive substrates (Ohio). In addition, the community members which were significantly different varied when different ISR-activecomposts were used (Ohio). To better characterize the shifts in microbial community structure during the development of ISR, population specific molecular tools were developed (Israel, Ohio).-PCR primers were designed to detect and quantify bacterial groups including Pyrenomycetes, Bacillus, Pan toea, Pseudomonas, Xanthomonas and Streptomyces as well as Trichoderma and Fusarium; two groups of fungi that harbor isolates which are ISR active (Isreal and Ohio). Bacterial consortia associated with cucumber plants grown in compost-amended potting mixtures were shown to be dominated by the phylogenetic taxon Bacteroidetes, including members of the genus Chryseobacterium, which in some cases have been shown to be involved in biocontrol (Israel). Nested-PCR-DGGE analyses coupled with long l6S rDNA sequencing, demonstrated that the Chryseobacteriumspp. detected on seed and the root in compost-amended treatments were derived from the compost itself. The most effective ISR inducing rhizobacterial strains were identified as Bacillus sp. based on partial sequencing of l6S rDNA. However, these strains were significantly less effective in reducing the severity of disease than Trichoderma hamatum382 (T382). A procedure was developed for inoculation of a compost-amended substrate with T -382 which consistently induced ISR in cucumber against Phytophthora blight caused by Phytophthora capsiciand in radish against bacterial spot (Ohio). Inoculation of compost-amended potting mixes with biocontrol agents such as T -382 and other microbes that induce systemic resistance in plants significantly increased the frequency of systemic disease control obtained with natural compost amendments.
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