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Journal articles on the topic 'T-helper'

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Author: Grafiati

Published: 4 June 2021

Last updated: 11 March 2023

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1

F. Abdel Hamid, Mahmoud, Safaa M. Morsy, Mostafa Abou El Ela, Rehab A. Hegazy, Marwa M. Fawzy, Laila A. Rashed, Ahmed M. Omar, Eman R. Abdel Fattah, and Doaa M. Hany. "T helper-17 cells and T regulatory cells in vitiligo." International Journal of Academic Research 5, no. 6 (December 10, 2013): 273–78. http://dx.doi.org/10.7813/2075-4124.2013/5-6/a.34.

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2

Noelle, R. "T helper cells." Current Opinion in Immunology 4, no. 3 (June 1992): 333–37. http://dx.doi.org/10.1016/0952-7915(92)90085-s.

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3

Ernerudh, J., A. Forsberg, E. Straka, E. Johansson, R. B. Mehta, J. Svensson, L. Matthiesen, et al. "T helper cells and T helper cell plasticity in pregnancy." Journal of Reproductive Immunology 90, no. 2 (August 2011): 131. http://dx.doi.org/10.1016/j.jri.2011.06.003.

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4

Khurana, Surbhi, Purva Mathur, Nidhi Bhardwaj, Minu Kumari, Sushma Sagar, Subodh Kumar, Amit Gupta, Richa Aggarwal, Kapil Dev Soni, and Rajesh Malhotra. "Dynamics of T helper 9, T helper 22, and regulatory T helper cells in minor & major trauma." Journal of Allergy and Clinical Immunology 143, no. 2 (February 2019): AB109. http://dx.doi.org/10.1016/j.jaci.2018.12.331.

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5

Dabbagh, Karim, and David B. Lewis. "Toll-like receptors and T-helper-1/T-helper-2 responses." Current Opinion in Infectious Diseases 16, no. 3 (June 2003): 199–204. http://dx.doi.org/10.1097/00001432-200306000-00003.

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6

Schwarz, Markus J., Sonnig Chiang, Norbert Müller, and Manfred Ackenheil. "T-helper-1 and T-helper-2 Responses in Psychiatric Disorders." Brain, Behavior, and Immunity 15, no. 4 (December 2001): 340–70. http://dx.doi.org/10.1006/brbi.2001.0647.

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7

Mjösberg, Jenny, Göran Berg, Maria C. Jenmalm, and Jan Ernerudh. "FOXP3+ Regulatory T Cells and T Helper 1, T Helper 2, and T Helper 17 Cells in Human Early Pregnancy Decidua1." Biology of Reproduction 82, no. 4 (April 1, 2010): 698–705. http://dx.doi.org/10.1095/biolreprod.109.081208.

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8

Hirahara, Kiyoshi, Ami Aoki, and Toshinori Nakayama. "Pathogenic helper T cells." Allergology International 70, no. 2 (April 2021): 169–73. http://dx.doi.org/10.1016/j.alit.2021.02.001.

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9

HERMANS G, BLOCKMANS D, BOCKAERT J, and BOBBAERS H. "Idiopathische T-helper lymfocytopenie." Tijdschrift voor Geneeskunde 54, no. 6 (January 1, 1998): 408–12. http://dx.doi.org/10.2143/tvg.54.6.5000073.

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10

Saravia, Jordy, Nicole M. Chapman, and Hongbo Chi. "Helper T cell differentiation." Cellular & Molecular Immunology 16, no. 7 (March 12, 2019): 634–43. http://dx.doi.org/10.1038/s41423-019-0220-6.

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11

Ferrarelli, L. K. "Unhelpful T Helper Cells." Science Signaling 7, no. 327 (May 27, 2014): ec141-ec141. http://dx.doi.org/10.1126/scisignal.2005514.

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12

Vinuesa, Carola G., Michelle A. Linterman, Di Yu, and Ian C. M. MacLennan. "Follicular Helper T Cells." Annual Review of Immunology 34, no. 1 (May 20, 2016): 335–68. http://dx.doi.org/10.1146/annurev-immunol-041015-055605.

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13

Swain, Susan L. "Helper T cell differentiation." Current Opinion in Immunology 11, no. 2 (April 1999): 180–85. http://dx.doi.org/10.1016/s0952-7915(99)80030-2.

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14

Romagnani, Sergio. "T Helper Cell Subsets." Clinical Immunotherapeutics 4, no. 2 (August 1995): 83–88. http://dx.doi.org/10.1007/bf03259073.

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15

Azuma, Naoko, Minoru Ando, Ken Tsuchiya, Takashi Akiba, and Hiroshi Nihei. "T helper 1 and T helper 2 balance in chronic hemodialysis patients." Nihon Toseki Igakkai Zasshi 35, no. 13 (2002): 1549–55. http://dx.doi.org/10.4009/jsdt.35.1549.

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16

Suzuki, Shunji, and Nozomi Ouchi. "T Helper 1/T Helper 2 Cell Immunity in Preeclamptic Twin Pregnancy." Journal of Nippon Medical School 74, no. 6 (2007): 434–36. http://dx.doi.org/10.1272/jnms.74.434.

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17

Thomi, Rahel, Simone Cazzaniga, S. Morteza Seyed Jafari, Christoph Schlapbach, and Robert E. Hunger. "Association of Hidradenitis Suppurativa With T Helper 1/T Helper 17 Phenotypes." JAMA Dermatology 154, no. 5 (May 1, 2018): 592. http://dx.doi.org/10.1001/jamadermatol.2018.0141.

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18

Smart, Joanne M., and Andrew S. Kemp. "Ontogeny of T-helper 1 and T-helper 2 cytokine production in childhood." Pediatric Allergy and Immunology 12, no. 4 (August 2001): 181–87. http://dx.doi.org/10.1034/j.1399-3038.2001.012004181.x.

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19

Iavicoli, Ivo, Luca Fontana, Alessandro Marinaccio, Antonio Bergamaschi, and Edward J. Calabrese. "Iridium alters immune balance between t helper 1 and t helper 2 responses." Human & Experimental Toxicology 29, no. 3 (January 22, 2010): 213–19. http://dx.doi.org/10.1177/0960327109360215.

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The recent introduction of iridium (Ir) into the catalytic converter has resulted in an increase of Ir levels into the environment, especially ambient air and soil. These observations suggested the need to evaluate potential toxicity due to Ir exposure. Since Ir compounds have been previously shown to cause immune sensitization in humans, the effects of Ir via drinking water for 90 days was assessed in adult female Wistar rats with respect to selected immune parameters. The Ir exposure induced dose-dependent decrease (p < .01) in T helper 1 (Th1) cytokines and increase (p < .001) in a T helper 2 (Th2) cytokine. The findings show that the Ir exposure affects an immune imbalance with a skewing toward a Th2 bias, a risk factor for asthma.

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20

Weinmann, Amy S. "Regulatory mechanisms that control T‐follicular helper and T‐helper 1 cell flexibility." Immunology & Cell Biology 92, no. 1 (October 2013): 34–39. http://dx.doi.org/10.1038/icb.2013.49.

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21

Osna, N., N. Vilgert, E. Hagina, G. Silonova, V. Kuse, L. Viksna, A. Sochnev, V. Gidraitis, A. Zvirbule, and M. Mauricas. "T helper 1/T helper 2 balance in pathogenesis of chronic hepatitis C." Immunology Letters 56 (May 1997): 146. http://dx.doi.org/10.1016/s0165-2478(97)85585-x.

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22

Osna, N. "T helper 1/T helper 2 balance in pathogenesis of chronic hepatitis C." Immunology Letters 56, no. 1-3 (May 1997): 146. http://dx.doi.org/10.1016/s0165-2478(97)87423-8.

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23

O’Garra, Anne, and Naoko Arai. "The molecular basis of T helper 1 and T helper 2 cell differentiation." Trends in Cell Biology 10, no. 12 (December 2000): 542–50. http://dx.doi.org/10.1016/s0962-8924(00)01856-0.

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24

Nuttall, T. J., P. A. Knight, S. M. McAleese, J. R. Lamb, and P. B. Hill. "T-helper 1, T-helper 2 and immunosuppressive cytokines in canine atopic dermatitis." Veterinary Immunology and Immunopathology 87, no. 3-4 (September 2002): 379–84. http://dx.doi.org/10.1016/s0165-2427(02)00076-4.

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25

Alayan, J., S. Ivanovski, and C. S. Farah. "Alveolar bone loss in T helper 1/T helper 2 cytokine-deficient mice." Journal of Periodontal Research 42, no. 2 (April 2007): 97–103. http://dx.doi.org/10.1111/j.1600-0765.2006.00920.x.

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26

Barkhordari, Elham, Nima Rezaei, Mahdi Mahmoudi, Pegah Larki, Hamid Reza Ahmadi-Ashtiani, Bita Ansaripour, Maryam Alighardashi, Mohammad Bashashati, Ali Akbar Amirzargar, and Naser Ebrahimi-Daryani. "T-Helper 1, T-Helper 2, and T-Regulatory Cytokines Gene Polymorphisms in Irritable Bowel Syndrome." Inflammation 33, no. 5 (February 23, 2010): 281–86. http://dx.doi.org/10.1007/s10753-010-9183-6.

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27

Kim, Bok-Kyu, Jong-Soon Lim, and Ki-Jung Kil. "Effects of Imperatae Rhizoma Extract on T helper 2 cell differentiation." Korea Journal of Herbology 29, no. 6 (November 30, 2014): 27–33. http://dx.doi.org/10.6116/kjh.2014.29.6.27.

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28

Balasubramani, Anand. "Priming T follicular helper cells." Science 358, no. 6368 (December 7, 2017): 1266.21–1268. http://dx.doi.org/10.1126/science.358.6368.1266-u.

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29

Mueller, K. "T Follicular Helper Cell Differentiation." Science Signaling 2, no. 85 (August 25, 2009): ec286-ec286. http://dx.doi.org/10.1126/scisignal.285ec286.

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30

Knight, Stella C., and Steven Patterson. "AIDS–beyond helper T cells." Lancet 348, no. 9028 (September 1996): 631. http://dx.doi.org/10.1016/s0140-6736(05)65070-2.

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31

Aronica, Mark A., Susan McCarthy, Shadi Swaidani, Daphne Mitchell, Mehmet Goral, James R. Sheller, and Mark Boothby. "Recall Helper T Cell Response." American Journal of Respiratory and Critical Care Medicine 169, no. 5 (March 2004): 587–95. http://dx.doi.org/10.1164/rccm.200301-100oc.

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32

Allan, Sarah. "Tailoring T-helper-cell responses." Nature Reviews Immunology 9, no. 2 (February 2009): 76. http://dx.doi.org/10.1038/nri2500.

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33

Laurent, C., N. Fazilleau, and P. Brousset. "A novel subset of T-helper cells: follicular T-helper cells and their markers." Haematologica 95, no. 3 (March 1, 2010): 356–58. http://dx.doi.org/10.3324/haematol.2009.019133.

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34

Bayes, H. K., and T. Evans. "P104 T Helper 1 and T Helper 22 cell responses against Pseudomonas aeruginosa infections." Thorax 65, Suppl 4 (November 16, 2010): A121—A122. http://dx.doi.org/10.1136/thx.2010.150987.5.

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35

Boniface, Katia, Bianca Blom, Yong-Jun Liu, and René de Waal Malefyt. "From interleukin-23 to T-helper 17 cells: human T-helper cell differentiation revisited." Immunological Reviews 226, no. 1 (December 2008): 132–46. http://dx.doi.org/10.1111/j.1600-065x.2008.00714.x.

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36

Nosbaum, Audrey, Aurore Rozieres, Brigitte Balme, Catherine Goujon, Jean-François Nicolas, and Frédéric Bérard. "Blocking T helper 1/T helper 17 pathways has no effect on patch testing." Contact Dermatitis 68, no. 1 (December 11, 2012): 58–59. http://dx.doi.org/10.1111/j.1600-0536.2012.02155.x.

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37

Kiyokawa, Yasuko, and Yoshio Yoneyama. "Relationship between adenosine and T-helper 1/T-helper 2 balance in hyperemesis gravidarum." Clinica Chimica Acta 370, no. 1-2 (August 2006): 137–42. http://dx.doi.org/10.1016/j.cca.2006.02.001.

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38

Mehrotra, Purvi, Purna Krishnamurthy, Jie Sun, Shreevrat Goenka, and Mark H. Kaplan. "Poly-ADP-ribosyl polymerase-14 promotes T helper 17 and follicular T helper development." Immunology 146, no. 4 (September 28, 2015): 537–46. http://dx.doi.org/10.1111/imm.12515.

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39

Dimitrov, Stoyan, Tanja Lange, Swantje Tieken, Horst L. Fehm, and Jan Born. "Sleep associated regulation of T helper 1/T helper 2 cytokine balance in humans." Brain, Behavior, and Immunity 18, no. 4 (July 2004): 341–48. http://dx.doi.org/10.1016/j.bbi.2003.08.004.

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40

Sahoo, Anupama, Shradha Wali, and Roza Nurieva. "T helper 2 and T follicular helper cells: Regulation and function of interleukin-4." Cytokine & Growth Factor Reviews 30 (August 2016): 29–37. http://dx.doi.org/10.1016/j.cytogfr.2016.03.011.

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41

Kalinski, Pawel, and Muriel Moser. "Consensual immunity: success-driven development of T-helper-1 and T-helper-2 responses." Nature Reviews Immunology 5, no. 3 (March 2005): 251–60. http://dx.doi.org/10.1038/nri1569.

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42

Schmitt, Nathalie, Yang Liu, Salah-Eddine Bentebibel, and Hideki Ueno. "Molecular Mechanisms Regulating T Helper 1 versus T Follicular Helper Cell Differentiation in Humans." Cell Reports 16, no. 4 (July 2016): 1082–95. http://dx.doi.org/10.1016/j.celrep.2016.06.063.

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43

Linehan, Jonathan, T. Dileepan, Pat Cleary, and Marc Jenkins. "Route of infection determines T helper-1 versus T helper-17 subset differentiation (46.9)." Journal of Immunology 182, no. 1_Supplement (April 1, 2009): 46.9. http://dx.doi.org/10.4049/jimmunol.182.supp.46.9.

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Abstract How environmental cues distinctly shape CD4+ T cell differentiation in response to specific bacterial infections remains largely unknown. Here we tested whether the route of infection determined which cytokines were produced by specific memory CD4+ T cells. Listeria monocytogenes and Streptococcus pyogenes were engineered to express the 2W1S antigenic peptide (LM-2W1S and SP-2W1S) and used to infect C57BL/6 mice. Endogenous 2W1S-specific CD4+ T cells were tracked using a 2W1S:I-Ab tetramer and magnetic bead enrichment. Infection with either LM-2W1S or SP-2W1S via the intranasal route resulted in splenic 2W1S:I-Ab-specific CD4+ memory cells that produced interleukin-17A (IL-17A) but not interferon-γ (IFN-γ) upon in vivo challenge, whereas infection with LM-2W1S or SP-2W1S via the intravenous route resulted in splenic 2W1S:I-Ab-specific memory cells that produced IFN-γ, but not IL-17A. These results suggest that the lymphoid environment of primary antigen encounter is an important factor in determining the type of CD4+ T cell memory generated and indicate that the route of immunization should be a major consideration when designing vaccines to improve cell-mediated immunity. This work was funded by the NIH.

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44

Siveke, Jens T., and Alf Hamann. "Cutting Edge: T Helper 1 and T Helper 2 Cells Respond Differentially to Chemokines." Journal of Immunology 160, no. 2 (January 15, 1998): 550–54. http://dx.doi.org/10.4049/jimmunol.160.2.550.

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Abstract T effector subsets, such as Th1 or Th2 cells, are key players in inflammatory reactions. It is not known whether chemokines are able to recruit these subsets differentially, as has been shown for memory vs naive T cells. Here we demonstrate that Th1 and Th2 cells differ in their intrinsic migratory properties and their chemotactic responsiveness toward distinct chemokines. While the CC-chemokines macrophage inflammatory protein (MIP)-1α, MIP-1β, and RANTES were efficient chemoattractants for Th1 cells, inducing a dose-dependent transmigration, Th2 cells were not attracted by these chemokines. Another CC-chemokine, JE/monocyte chemoattractant protein (MCP)-1, and a CXC-chemokine, stromal cell-derived factor (SDF)-1α, exerted chemotactic effects on both Th1 and Th2 cells, but differences in sensitivity and the percentage of responding cells were recorded between both subsets. These results indicate that chemokines play a distinct role in the regulation of local immune reactions by influencing the local balance between proinflammatory and antiinflammatory T cell subsets.

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45

Hale, J. Scott, Andrew Baessler, Camille L. Novis, Zuolian Shen, Jelena Perovanovic, Mark Wadsworth, Linda M. Sircy, Malia Harrison-Chau, Katherine E. Varley, and Dean R. Tantin. "Tet2-mediated programing balances T follicular helper cell and T helper 1 cell differentiation." Journal of Immunology 208, no. 1_Supplement (May 1, 2022): 112.24. http://dx.doi.org/10.4049/jimmunol.208.supp.112.24.

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Abstract The differentiation of CD4+ T cell subsets in response to infection has been studied extensively, however the epigenetic programs that regulate these processes remain poorly understood. Active demethylation by tet methylcytosine dioxygenases of CpG dinucleotides within DNA is a key component of epigenetic programing that promotes lineage specific gene expression and contributes to cellular differentiation and function. Here we report that Tet2 acts to restrict the differentiation of T follicular helper (Tfh) cells in CD4+ T cells responding to viral infection. Using an adoptive transfer model of virus-specific CD4+ cells we found that Tet2-deficient CD4+ T cells skew away from the Th1 lineage and instead preferentially differentiate into highly functional germinal center (GC) Tfh cells that provide enhanced help for B cell responses. We found that the impact of Tet2-mediated programing on CD4+ T cell differentiation is cell intrinsic and the shift in lineage differentiation occurs as early as 2 days post infection. Using genome-wide expression, DNA methylation and transcription factor binding analyses, we found that Tet2 coordinates with multiple transcription factors to mediate the demethylation and expression of their target genes following activation. Our findings establish Tet2 as an important regulator of Tfh cell differentiation and reveal pathways that could be targeted to enhance GC responses against infectious disease. Supported by grants from NIH (R01 AI137238 to J.S.H., T32 AI055434 to L.M.S., and T32 AI138945 to A.B.

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46

Stewart, Tracy Murray, Cassandra E. Holbert, and Robert A. Casero. "Helping the helpers: polyamines help maintain helper T-cell lineage fidelity." Immunometabolism 4, no. 3 (July 2022): e00002. http://dx.doi.org/10.1097/in9.0000000000000002.

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47

Mitsdoerffer, M., Y. Lee, A. Jager, H. J. Kim, T. Korn, J. K. Kolls, H. Cantor, E. Bettelli, and V. K. Kuchroo. "Proinflammatory T helper type 17 cells are effective B-cell helpers." Proceedings of the National Academy of Sciences 107, no. 32 (July 26, 2010): 14292–97. http://dx.doi.org/10.1073/pnas.1009234107.

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48

Ciavarra, Richard P. "T helper cells in cytotoxic T lymphocyte development: Analysis of the cellular basis for deficient T helper cell function in the L3T4-independent T helper cell pathway." Cellular Immunology 134, no. 2 (May 1991): 427–41. http://dx.doi.org/10.1016/0008-8749(91)90315-3.

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49

Sharma, Alpana, Rehan Khan, Suhasini Joshi, Lalit Kumar, and Manoj Sharma. "Dysregulation in T helper 1/T helper 2 cytokine ratios in patients with multiple myeloma." Leukemia & Lymphoma 51, no. 5 (March 31, 2010): 920–27. http://dx.doi.org/10.3109/10428191003699563.

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50

Hara, Toshiro, Sumimasa Yamashita, Hideo Aiba, Kenji Nihei, Nobuo Koide, Robert A. Good, and Kenzo Takeshita. "Measles virus-specific T helper 1/T helper 2-cytokine production in subacute sclerosing panencephalitis." Journal of Neurovirology 6, no. 2 (January 2000): 121–26. http://dx.doi.org/10.3109/13550280009013155.

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