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Journal articles on the topic 'T cells'

Author: Grafiati

Published: 4 June 2021

Last updated: 31 July 2024

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1

F. Abdel Hamid, Mahmoud, Safaa M. Morsy, Mostafa Abou El Ela, Rehab A. Hegazy, Marwa M. Fawzy, Laila A. Rashed, Ahmed M. Omar, Eman R. Abdel Fattah, and Doaa M. Hany. "T helper-17 cells and T regulatory cells in vitiligo." International Journal of Academic Research 5, no. 6 (December 10, 2013): 273–78. http://dx.doi.org/10.7813/2075-4124.2013/5-6/a.34.

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2

Singh, Yuvraj. "Chimeric Antigen Receptors T Cells (CAR T) Therapy." International Journal of Science and Research (IJSR) 13, no. 5 (May 5, 2024): 1563–66. http://dx.doi.org/10.21275/sr24523173932.

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3

Y, Elshimali. "Chimeric Antigen Receptor T-Cell Therapy (Car T-Cells) in Solid Tumors, Resistance and Success." Bioequivalence & Bioavailability International Journal 6, no. 1 (2022): 1–6. http://dx.doi.org/10.23880/beba-16000163.

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CARs are chimeric synthetic antigen receptors that can be introduced into an immune cell to retarget its cytotoxicity toward a specific tumor antigen. CAR T-cells immunotherapy demonstrated significant success in the management of hematologic malignancies. Nevertheless, limited studies are present regarding its efficacy in solid and refractory tumors. It is well known that the major concerns regarding this technique include the risk of relapse and the resistance of tumor cells, in addition to high expenses and limited affordability. Several factors play a crucial role in improving the efficacy of immunotherapy, including tumor mutation burden (TMB), microsatellite instability (MSI), loss of heterozygosity (LOH), the APOBEC Protein Family, tumor microenvironment (TMI), and epigenetics. In this minireview, we address the current and future applications of CAR T-Cells against solid tumors and their measure for factors of resistance and success.

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4

CPK, Cheung. "T Cells, Endothelial Cell, Metabolism; A Therapeutic Target in Chronic Inflammation." Open Access Journal of Microbiology & Biotechnology 5, no. 2 (2020): 1–6. http://dx.doi.org/10.23880/oajmb-16000163.

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The role of metabolic reprogramming in the coordination of the immune response has gained increasing consideration in recent years. Indeed, it has become clear that changes in the metabolic status of immune cells can alter their functional properties. During inflammation, stimulated immune cells need to generate sufficient energy and biomolecules to support growth, proliferation and effector functions, including migration, cytotoxicity and production of cytokines. Thus, immune cells switch from oxidative phosphorylation to aerobic glycolysis, increasing their glucose uptake. A similar metabolic reprogramming has been described in endothelial cells which have the ability to interact with and modulate the function of immune cells and vice versa. Nonetheless, this complicated interplay between local environment, endothelial and immune cells metabolism, and immune functions remains incompletely understood. We analyze the metabolic reprogramming of endothelial and T cells during inflammation and we highlight some key components of this metabolic switch that can lead to the development of new therapeutics in chronic inflammatory disease.

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5

Meuer, Stefan C. "T cells." Immunology Today 12, no. 1 (January 1991): 49. http://dx.doi.org/10.1016/0167-5699(91)90117-c.

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6

Stauss, Hans J. "Engineered T cells can fight malignant T cells." Blood 126, no. 8 (August 20, 2015): 927–28. http://dx.doi.org/10.1182/blood-2015-07-652057.

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7

Scott, David W. "T regulatory cells turn on T regulatory cells." Blood 114, no. 19 (November 5, 2009): 3975–76. http://dx.doi.org/10.1182/blood-2009-09-241406.

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8

Zahran F, Zahran F., Al-haggar M. Al-haggar M, and Derbala S. A. Derbala S.A. "Regulatory T Cells in Pediatric Lupus Nephritis." Indian Journal of Applied Research 3, no. 10 (October 1, 2011): 1–3. http://dx.doi.org/10.15373/2249555x/oct2013/91.

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9

Ng, Y. H., M. H. Oberbarnscheidt, H. C. K. Chandramoorthy, R. Hoffman, and G. Chalasani. "B Cells Help Alloreactive T Cells Differentiate Into Memory T Cells." American Journal of Transplantation 10, no. 9 (August 27, 2010): 1970–80. http://dx.doi.org/10.1111/j.1600-6143.2010.03223.x.

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10

Suzuki, Haruhiko, Zhe Shi, Yusuke Okuno, and Ken-ichi Isobe. "Are CD8+CD122+ cells regulatory T cells or memory T cells?" Human Immunology 69, no. 11 (November 2008): 751–54. http://dx.doi.org/10.1016/j.humimm.2008.08.285.

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11

Parham, Peter. "T cells or T shirts?" Nature 347, no. 6293 (October 1990): 589–90. http://dx.doi.org/10.1038/347589c0.

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12

Kronenberg, Mitchell, and Wendy L. Havran. "Frontline T cells: γδ T cells and intraepithelial lymphocytes." Immunological Reviews 215, no. 1 (February 2007): 5–7. http://dx.doi.org/10.1111/j.1600-065x.2006.00489.x.

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13

Iwahori, Kota, Sunitha Kakarla, Mireya P. Velasquez, Feng Yu, Zongzhen Yi, Claudia Gerken, Xiao-Tong Song, and Stephen Gottschalk. "Engager T Cells: A New Class of Antigen-specific T Cells That Redirect Bystander T Cells." Molecular Therapy 23, no. 1 (January 2015): 171–78. http://dx.doi.org/10.1038/mt.2014.156.

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14

Minkel, JR. "T Cells for Brain Cells." Scientific American 294, no. 1 (January 2006): 21–22. http://dx.doi.org/10.1038/scientificamerican0106-21.

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15

Foley, J. F. "T Cells TAMing Dendritic Cells." Science Signaling 6, no. 288 (August 13, 2013): ec191-ec191. http://dx.doi.org/10.1126/scisignal.2004609.

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16

Rappl, Gunter, David Schrama, Andreas Hombach, Eva Katharina Meuer, Annette Schmidt, Jürgen C. Becker, and Hinrich Abken. "CD7−T Cells are Late Memory Cells Generated from CD7+T Cells." Rejuvenation Research 11, no. 3 (June 2008): 543–56. http://dx.doi.org/10.1089/rej.2007.0612.

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17

Jameson, Stephen C. "T cell homeostasis: Keeping useful T cells alive and live T cells useful." Seminars in Immunology 17, no. 3 (June 2005): 231–37. http://dx.doi.org/10.1016/j.smim.2005.02.003.

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18

Robbins, Paul F. "T-Cell Receptor–Transduced T Cells." Cancer Journal 21, no. 6 (2015): 480–85. http://dx.doi.org/10.1097/ppo.0000000000000160.

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19

Alderton, Gemma. "Recruiting T cells." Science 372, no. 6538 (April 8, 2021): 141.10–143. http://dx.doi.org/10.1126/science.372.6538.141-j.

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20

Tudor, Thilan, Zev A. Binder, and Donald M. O’Rourke. "CAR T Cells." Neurosurgery Clinics of North America 32, no. 2 (April 2021): 249–63. http://dx.doi.org/10.1016/j.nec.2020.12.005.

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21

Blosser, Emily G., and David A. Randolph. "CD4 T Cells." NeoReviews 14, no. 9 (September 2013): e456-e462. http://dx.doi.org/10.1542/neo.14-9-e456.

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22

Urba, Walter J., and Dan L. Longo. "Redirecting T Cells." New England Journal of Medicine 365, no. 8 (August 25, 2011): 754–57. http://dx.doi.org/10.1056/nejme1106965.

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23

Nyanhete, Tinashe, and Georgia D. Tomaras. "CD8+ T cells." AIDS 32, no. 18 (November 2018): 2835–38. http://dx.doi.org/10.1097/qad.0000000000002008.

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24

Al Dulaijan, Basmah S., Amr Mansouri, Jordan Karnyski, and Jamil Azzi. "Regulatory T cells." Current Opinion in Organ Transplantation 23, no. 1 (February 2018): 1–7. http://dx.doi.org/10.1097/mot.0000000000000491.

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25

Mudter, Jonas, and Markus F. Neurath. "Mucosal T cells." Current Opinion in Gastroenterology 19, no. 4 (July 2003): 343–49. http://dx.doi.org/10.1097/00001574-200307000-00004.

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26

Allez, Matthieu, and Lloyd Mayer. "Regulatory T Cells." Inflammatory Bowel Diseases 10, no. 5 (September 2004): 666–76. http://dx.doi.org/10.1097/00054725-200409000-00027.

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27

Ansell, Stephen M., and Paolo Corradini. "CAR T-cells." HemaSphere 3, no. 3 (June 2019): e209. http://dx.doi.org/10.1097/hs9.0000000000000209.

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28

Rusk, Nicole. "Antitumor T cells." Nature Methods 16, no. 1 (December 20, 2018): 19. http://dx.doi.org/10.1038/s41592-018-0271-0.

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29

Lou, Kai-Jye. "Wounded T cells." Science-Business eXchange 2, no. 14 (April 2009): 564. http://dx.doi.org/10.1038/scibx.2009.564.

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30

Alderton, Gemma. "Mobilizing T cells." Science 366, no. 6463 (October 17, 2019): 320.17–322. http://dx.doi.org/10.1126/science.366.6463.320-q.

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31

Pujanandez, Lindsey. "Tempting T cells." Science 368, no. 6497 (June 18, 2020): 1324.19–1326. http://dx.doi.org/10.1126/science.368.6497.1324-s.

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32

Garin, Marina I., and Robert I. Lechler. "Regulatory T cells." Current Opinion in Organ Transplantation 8, no. 1 (March 2003): 7–12. http://dx.doi.org/10.1097/00075200-200303000-00003.

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33

LeBrasseur, Nicole. "Antagonizing T cells." Journal of Cell Biology 166, no. 4 (August 16, 2004): 442. http://dx.doi.org/10.1083/jcb1664iti2.

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34

Mueller, K. "Starving T Cells." Science Signaling 2, no. 74 (June 9, 2009): ec192-ec192. http://dx.doi.org/10.1126/scisignal.274ec192.

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35

Van Epps, Heather L. "Disruptive T cells." Journal of Experimental Medicine 203, no. 1 (January 17, 2006): 4. http://dx.doi.org/10.1084/jem2031iti5.

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36

Mathé, G. "Suppressor T-cells." Biomedicine & Pharmacotherapy 53, no. 5-6 (June 1999): 213–17. http://dx.doi.org/10.1016/s0753-3322(99)80090-0.

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37

Bluestone, Jeffrey A., and Harald von Boehmer. "Regulatory T cells." Seminars in Immunology 18, no. 2 (April 2006): 77. http://dx.doi.org/10.1016/j.smim.2006.01.003.

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38

MERKENSCHLAGER, MATTHIAS, and PETER C. L. BEVERLEY. "Memory T cells." Nature 341, no. 6241 (October 1989): 392. http://dx.doi.org/10.1038/341392b0.

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39

Sakaguchi, Shimon. "Regulatory T Cells." Cell 101, no. 5 (May 2000): 455–58. http://dx.doi.org/10.1016/s0092-8674(00)80856-9.

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40

Thornton, Angela M. "T regulatory cells." Current Biology 15, no. 15 (August 2005): R582. http://dx.doi.org/10.1016/j.cub.2005.07.048.

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41

Sakaguchi, Shimon. "Regulatory T cells." Springer Seminars in Immunopathology 28, no. 1 (August 5, 2006): 1–2. http://dx.doi.org/10.1007/s00281-006-0043-2.

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42

Maloney, David G. "CAR-T Cells." Clinical Lymphoma Myeloma and Leukemia 19 (September 2019): S100—S101. http://dx.doi.org/10.1016/j.clml.2019.07.435.

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43

Foley, J. F. "Polyfunctional T Cells." Science Signaling 5, no. 210 (February 7, 2012): ec42-ec42. http://dx.doi.org/10.1126/scisignal.2002929.

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44

Dempsey, Laurie A. "4PD1hi T cells." Nature Immunology 19, no. 7 (June 20, 2018): 647. http://dx.doi.org/10.1038/s41590-018-0149-4.

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45

Baas, Tracey. "Rejuvenating T cells." Science-Business eXchange 6, no. 5 (February 2013): 107. http://dx.doi.org/10.1038/scibx.2013.107.

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46

Gardner, Rebecca A., and Michael C. Jensen. "CD19CAR T Cells." Cancer Journal 20, no. 2 (2014): 107–11. http://dx.doi.org/10.1097/ppo.0000000000000030.

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47

Golovina, Tatiana N., and Robert H. Vonderheide. "Regulatory T Cells." Cancer Journal 16, no. 4 (July 2010): 342–47. http://dx.doi.org/10.1097/ppo.0b013e3181eb336d.

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48

Dempsey, Laurie A. "Aging T cells." Nature Immunology 13, no. 12 (November 16, 2012): 1143. http://dx.doi.org/10.1038/ni.2487.

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49

Dempsey, Laurie A. "Dysfunctional T cells." Nature Immunology 14, no. 11 (October 21, 2013): 1117. http://dx.doi.org/10.1038/ni.2754.

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50

Fehervari, Zoltan. "Fueling T cells." Nature Immunology 16, no. 2 (January 16, 2015): 141. http://dx.doi.org/10.1038/ni.3088.

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