Academic literature on the topic 'T cell diversity'

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Journal articles on the topic "T cell diversity"

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Newrzela, S., N. Al-Ghaili, T. Heinrich, et al. "T-cell receptor diversity prevents T-cell lymphoma development." Leukemia 26, no. 12 (2012): 2499–507. http://dx.doi.org/10.1038/leu.2012.142.

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Stromberg, Sean P., and Jean M. Carlson. "Diversity of T-cell responses." Physical Biology 10, no. 2 (2013): 025002. http://dx.doi.org/10.1088/1478-3975/10/2/025002.

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GORONZY, J., W. LEE, and C. WEYAND. "Aging and T-cell diversity☆." Experimental Gerontology 42, no. 5 (2007): 400–406. http://dx.doi.org/10.1016/j.exger.2006.11.016.

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Nelson, J. "STKE: Celebrating T Cell Diversity." Science 295, no. 5557 (2002): 933b—933. http://dx.doi.org/10.1126/science.295.5557.933b.

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Robins, Harlan S., Paulo V. Campregher, Santosh K. Srivastava та ін. "Comprehensive assessment of T-cell receptor β-chain diversity in αβ T cells". Blood 114, № 19 (2009): 4099–107. http://dx.doi.org/10.1182/blood-2009-04-217604.

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Abstract The adaptive immune system uses several strategies to generate a repertoire of T- and B-cell antigen receptors with sufficient diversity to recognize the universe of potential pathogens. In αβ T cells, which primarily recognize peptide antigens presented by major histocompatibility complex molecules, most of this receptor diversity is contained within the third complementarity-determining region (CDR3) of the T-cell receptor (TCR) α and β chains. Although it has been estimated that the adaptive immune system can generate up to 1016 distinct αβ pairs, direct assessment of TCR CDR3 dive
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Sato, Kayoko. "Helper T Cell Diversity and Plasticity." Circulation Journal 78, no. 12 (2014): 2843–44. http://dx.doi.org/10.1253/circj.cj-14-1164.

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Born, Willi K., M. Kemal Aydintug та Rebecca L. O'Brien. "Diversity of γδ T-cell antigens". Cellular & Molecular Immunology 10, № 1 (2012): 13–20. http://dx.doi.org/10.1038/cmi.2012.45.

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Parish, Ian A., and Susan M. Kaech. "Diversity in CD8+ T cell differentiation." Current Opinion in Immunology 21, no. 3 (2009): 291–97. http://dx.doi.org/10.1016/j.coi.2009.05.008.

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Nakayamada, Shingo, Hayato Takahashi, Yuka Kanno, and John J. O'Shea. "Helper T cell diversity and plasticity." Current Opinion in Immunology 24, no. 3 (2012): 297–302. http://dx.doi.org/10.1016/j.coi.2012.01.014.

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Kemir, C. "Diversity of Human T Cell Receptors." Science 288, no. 5469 (2000): 1135a—1135. http://dx.doi.org/10.1126/science.288.5469.1135a.

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Dissertations / Theses on the topic "T cell diversity"

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Golby, Sarah Jane Charity. "Diversity of T cell subsets in mucosal microenvironments." Thesis, King's College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.369221.

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Furmanski, Anna Louise. "Diversity and selection of the murine T-cell repertoire." Thesis, Imperial College London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.434779.

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Lee, Edward S. "Quantifying the development, size, and repertoire diversity of T cell populations." Thesis, University of Glasgow, 2018. http://theses.gla.ac.uk/31002/.

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The adaptive immune system must be able to respond to virtually any pathogen that the body encounters. T cell immunity is able to do so by developing a diverse repertoire of T cell receptors and maintaining large numbers of T cells. These two quantitative properties are fundamental for the ability of T cell-mediated immunity to clear infections and generate memory cells for future protection. The aims of this thesis are to quantify the sizes of T cell populations, to develop tools to measure the diversity of T cell repertoires, and to describe how T cell populations develop in neonatal mice. W
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Trichot, Coline. "Regulation of Human T Helper Cell Diversity : From In Vitro Dendritic Cell-Based Mechanisms to Candidate Biomarkers in Atopic Dermatitis." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLS423.

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Le système immunitaire humain est majoritairement commandé par les cellules dendritiques et les lymphocytes T auxiliaires. Lorsque les cellules dendritiques détectent un pathogène, elles vont instruire les lymphocytes T auxiliaires afin qu’ils adoptent le phénotype approprié à la menace rencontrée. Les lymphocytes T auxiliaires peuvent être divisés en plusieurs sous-populations, caractérisées par la production de cytokines spécifiques. Chaque sous-population de lymphocyte T auxiliaire possède des fonctions propres et est impliquée dans l’élimination de pathogènes distincts. Si les réponses des
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Stirk, Emily Ruth. "Stochastic modelling of diversity and ageing in the naive T cell repertoire." Thesis, University of Leeds, 2010. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.531516.

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Brookes, Roger Hamilton. "Generation of diversity in T cell epitope hierarchy by different routes of immunisation with simian immunodeficiency virus core protein." Thesis, King's College London (University of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283133.

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Singh, Ogesh. "Regulatory T cell diversity analysis and a gene transfer approach to cellular immunotherapy in a murine model of type one diabetes." Thesis, Royal Veterinary College (University of London), 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.522749.

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Jurewicz, Mollie M. "The non-classical MHC-II molecule DO regulates diversity of the immunopeptidome and selection of the CD4 regulatory T cell lineage." eScholarship@UMMS, 2019. https://escholarship.umassmed.edu/gsbs_diss/1030.

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Presentation of antigenic peptides on MHC-II molecules is essential for induction of tolerance to self and for effective immunity against foreign pathogens. The non- classical MHC-II molecule DO (HLA-DO in humans, H2-O in mice) functions in selection of MHC-II epitopes by competitively inhibiting the peptide exchange factor DM. Previous studies have suggested a role for DO in development of autoimmunity and in the immune response to retroviral infection, presumably via modulation of the MHC-II peptidome, but the precise effect of DO has been difficult to discern. Through characterization of th
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Ameres, Stefanie Verfasser], and Horst [Akademischer Betreuer] [Domdey. "The T cell repertoire specific for the IE-1 protein of human cytomegalovirus : diversity, function and evasion / Stefanie Ameres. Betreuer: Horst Domdey." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2013. http://d-nb.info/104831099X/34.

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Karpf, Léa. "Systematic Study of OX40 Ligand Context-Dependent Function on Human T Helper Cell Polarization A Quantitative Multivariate Model of Human Dendritic Cell-T Helper Cell Communication TH Cell Diversity and Response to Dupilumab in Patients With Atopic Dermatitis Inborn Errors of Type I IFN Immunity in Patients With Life-Threatening COVID-19 Quantitative Modeling of OX40 Ligand Context-Dependent Function on Human T Helper Cell SARS-CoV-2 Induces Activation and Diversification of Human Plasmacytoid Pre-Dendritic Cells." Thesis, université Paris-Saclay, 2020. http://www.theses.fr/2020UPASL044.

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L'immunité adaptative est principalement orchestrée par des lymphocytes T CD4 auxiliaires. Ils ont la capacité de se polariser en plusieurs sous-populations, chacune associée à un phénotype approprié au pathogène rencontré. L'activation des lymphocytes T auxiliaires peut être régulée par des checkpoints immunitaires co-stimulateurs, tel que OX40 Ligand, ou co-inhibiteurs. Ces molécules ont été étudiées individuellement, dans des conditions spécifiques. Cependant, la contexte-dépendance pourrait expliquer une grande partie de la variabilité fonctionnelle des biomolécules. Il n'y a actuellement
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Books on the topic "T cell diversity"

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B, Schook Lawrence, Tew John G, and International RES Symposium (1987 : Richmond, Va.), eds. Antigen presenting cells: Diversity, differentiation, and regulation : proceedings of a symposium held in Richmond, Virginia, March 26-29, 1987. Liss, 1988.

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Galley, Kevin Andrew. Analysis of junctional region diversity of TCR[beta] cDNA from pancreatic islet-infiltrating T cells of young prediabetic nonobese diabetic mice. National Library of Canada, 1994.

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Soboloff, Jonathan, and Dietmar J. Kappes. Signaling Mechanisms Regulating T Cell Diversity and Function. Taylor & Francis Group, 2017.

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Soboloff, Jonathan, and Dietmar J. Kappes. Signaling Mechanisms Regulating T Cell Diversity and Function. Taylor & Francis Group, 2017.

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Soboloff, Jonathan, and Dietmar J. Kappes. Signaling Mechanisms Regulating T Cell Diversity and Function. Taylor & Francis Group, 2021.

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Soboloff, Jonathan, and Dietmar J. Kappes. Signaling Mechanisms Regulating T Cell Diversity and Function. Taylor & Francis Group, 2017.

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Soboloff, Jonathan, and Dietmar J. Kappes. Signaling Mechanisms Regulating T Cell Diversity and Function. Taylor & Francis Group, 2017.

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Signaling Mechanisms Regulating T Cell Diversity and Function. Taylor & Francis Group, 2017.

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Klingenberg, Roland, and Ulf Müller-Ladner. Mechanisms of inflammation. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0270.

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This chapter provides a brief summary of the immune pathogenesis of atherosclerosis, highlighting shared features with inflammatory pathways in rheumatoid arthritis (RA) described in detail in Chapter 25.4. RA constitutes a prototype autoimmune disease primarily affecting the joints but also the heart and vessels associated with increased cardiovascular mortality. Recent years have produced a wealth of novel insights into the diversity of immune cell types which either propagate or dampen inflammation in atherogenesis. Expansion of this inherent anti-inflammatory component carried by regulator
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Liede-Schumann, Sigrid, Ulrich Meve, Gildas Gâteblé, Gabrielle Barriera, and Silvio Fici. Apocynaceae pro parte, Phellinaceae, Capparaceae : Flore de la Nouvelle Calédonie, volume 27. Publications scientifiques du Muséum, Paris ; IRD, Marseille, 2020. http://dx.doi.org/10.5852/fft49.

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L’exceptionnelle richesse floristique de la Nouvelle-Calédonie est mondialement connue. Plus de 3 400 espèces de plantes vasculaires indigènes y sont répertoriées, dont les trois-quarts sont endémiques de l’archipel. L’endémisme ne concerne pas seulement les espèces, mais aussi les genres (près d’une centaine) et même trois familles. La diversité se décline aussi sur le plan écologique, en lien avec l’histoire géologique originale de la Nouvelle-Calédonie, qui a favorisé le micro-endémisme et les espèces inféodées aux substrats ultramafiques. De nouvelles espèces continuent à être découvertes,
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Book chapters on the topic "T cell diversity"

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Gustafson, Claire E., David L. Lamar, Cornelia M. Weyand, and Jörg J. Goronzy. "Age, T Cell Homeostasis, and T Cell Diversity in Humans." In Handbook of Immunosenescence. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-99375-1_9.

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Gustafson, Claire E., David L. Lamar, Cornelia M. Weyand, and Jörg J. Goronzy. "Age, T Cell Homeostasis, and T Cell Diversity in Humans." In Handbook of Immunosenescence. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-64597-1_9-1.

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Purushe, Janaki, and Yi Zhang. "Histone Methyltransferases and T Cell Heterogeneity." In Signaling Mechanisms Regulating T Cell Diversity and Function. CRC Press, 2017. http://dx.doi.org/10.1201/9781315371689-11.

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O’Boyle, Kaitlin C., Takuya Ohtani, Sasikanth Manne, et al. "Exploration of T-Cell Diversity Using Mass Cytometry." In Methods in Molecular Biology. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0266-9_1.

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Cho, Jonathan J., Kyle J. Lorentsen, and Dorina Avram. "Models of Regulatory T Cell Alterations and Systemic Autoimmunity." In Signaling Mechanisms Regulating T Cell Diversity and Function. CRC Press, 2017. http://dx.doi.org/10.1201/9781315371689-12.

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Charbonnier, Louis-Marie, and Talal A. Chatila. "Phenotypic and Functional Characterization of Regulatory T Cell Populations." In Signaling Mechanisms Regulating T Cell Diversity and Function. CRC Press, 2017. http://dx.doi.org/10.1201/9781315371689-7.

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Fahl, Shawn P., Dietmar J. Kappes, and David L. Wiest. "TCR Signaling Circuits in αβ/γδ T Lineage Choice." In Signaling Mechanisms Regulating T Cell Diversity and Function. CRC Press, 2017. http://dx.doi.org/10.1201/9781315371689-6.

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Heller, Nicola M., Rosa Berga-Bolanos, Lynette Naler, and Jyoti Misra Sen. "Natural Killer T (NKT) Cells in Mice and Men." In Signaling Mechanisms Regulating T Cell Diversity and Function. CRC Press, 2017. http://dx.doi.org/10.1201/9781315371689-8.

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Barnett, John B. "Consequences of Blocking the Choreography of Double Negative Thymocyte Maturation." In Signaling Mechanisms Regulating T Cell Diversity and Function. CRC Press, 2017. http://dx.doi.org/10.1201/9781315371689-1.

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Samakai, Elsie, Christina Go, and Jonathan Soboloff. "Defining the Roles of Ca2+ Signals during T Cell Activation." In Signaling Mechanisms Regulating T Cell Diversity and Function. CRC Press, 2017. http://dx.doi.org/10.1201/9781315371689-10.

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Conference papers on the topic "T cell diversity"

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Grinshpun, Boris, Jennifer Sims, Peter Canoll, Jeffrey N. Bruce, Peter Sims, and Yufeng Shen. "Analyzing T cell repertoire diversity by high-throughput sequencing." In 2013 IEEE Global Conference on Signal and Information Processing (GlobalSIP). IEEE, 2013. http://dx.doi.org/10.1109/globalsip.2013.6736810.

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Baracho, Gisele V., Stephanie Widmann, and Aaron Tyznik. "Abstract 1815: Defining cell population diversity and T cell dysfunction in a mouse model of obesity." In Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-1815.

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Patel, Preeyam, Marcos Iglesias, Qin Tang, Megan Biller, Alireza Alavi, and Ayako Pedersen. "1029 T cell receptor diversity analysis ofin vitro-expanded T cells against IDO1 and PD-L1-derived peptides." In SITC 38th Annual Meeting (SITC 2023) Abstracts. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/jitc-2023-sitc2023.1029.

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Yuguo, Song, Xiang Lei, and Bi Shengli. "Analysis of T cell receptor V beta diversity in peripheral CD8(+) T lymphocytes in patients with hepatitis B infection." In 2011 International Conference on Human Health and Biomedical Engineering (HHBE). IEEE, 2011. http://dx.doi.org/10.1109/hhbe.2011.6027968.

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ISHIDA, Y. "A STABILITY AND DIVERSITY ANALYSIS ON A MATHEMATICAL MODEL OF THE INTERACTION BETWEEN HIV AND T-CELL CD4+." In Proceedings of the Fourth Asian Symposium (ASCM 2000). WORLD SCIENTIFIC, 2000. http://dx.doi.org/10.1142/9789812791962_0036.

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Fan, Li, Angelo Harris, Patrick Franken, et al. "80 Association ofin situT-cell receptor diversity and tumor adjacent immune cells to checkpoint inhibitor response in head and neck squamous cell carcinoma (HNSCC)." In SITC 38th Annual Meeting (SITC 2023) Abstracts. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/jitc-2023-sitc2023.0080.

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Choudhury, Noura, Kai Lee Yap, Kazuma Kiyotani, et al. "Abstract 4899: Tumor T-cell receptor (TCR) diversity elucidates the immune response to genetic alterations of muscle-invasive bladder cancer." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-4899.

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Gu, Chenyi, Kenichi Shimada, Lukas Kania, Daniel E. Michaud, Madeline G. Townsend, and Jennifer L. Guerriero. "499 Myeloid diversity in hormone receptor positive breast cancer reveals myeloid and lymphoid signaling pathways that correlate with T cell inhibition." In SITC 38th Annual Meeting (SITC 2023) Abstracts. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/jitc-2023-sitc2023.0499.

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Shu, Tong, Hong Zheng, Yunong Gao, Min Gao, Zhipeng Zhou, and Jing Bai. "EP285/#110 Circulating T-cell receptor diversity as prognostic biomarker for PARP inhibitors maintenance therapy in high-grade serous ovarian cancer." In IGCS 2022 Annual Meeting Abstracts. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/ijgc-2022-igcs.376.

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Mackay, Sean, Jon Chen, Jeremy Patino, Y. David Seo, Seth Pollack, and Jing Zhou. "Abstract LB-190: Single-cell polyfunctionality of circulating CD4+ T cells correlates with T cell receptor repertoire diversity of PBMCs, indicating potential synergistic activity and peripheral biomarker predictive of efficacy of intratumor injection of the toll-like receptor 4 agonist G100." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-lb-190.

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Reports on the topic "T cell diversity"

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Fahima, Tzion, and Jorge Dubcovsky. Map-based cloning of the novel stripe rust resistance gene YrG303 and its use to engineer 1B chromosome with multiple beneficial traits. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7598147.bard.

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Research problem: Bread wheat (Triticumaestivum) provides approximately 20% of the calories and proteins consumed by humankind. As the world population continues to increase, it is necessary to improve wheat yields, increase grain quality, and minimize the losses produced by biotic and abiotic stresses. Stripe rust, caused by Pucciniastriiformisf. sp. tritici(Pst), is one of the most destructive diseases of wheat. The new pathogen races are more virulent and aggressive than previous ones and have produced large economic losses. A rich source for stripe-rust resistance genes (Yr) was found in w
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