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Dissertations / Theses on the topic 'Systemic model'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Leung, Wai-hin, and 梁瑋軒. "Neurogenesis in animal model of systemic lupus erythematosus." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/209497.

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Systemic Lupus Erythematosus (SLE) is an autoimmune disease which is characterized by high level of autoantibody detected in the body. This disease is female predominant with a male to female ratio 1: 9. SLE could cause damage to different organ systems and central nervous system is one of them. Patients diagnosed with SLE could suffer from psychiatric problems like cognitive dysfunction, depression and anxiety. Neurogenesis refers to the process by which new neurons are generated. Although it has been widely reported that neurogenesis could be enhanced under pathological conditions such as

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2

Stierand, Marc B. "Phenomenological model of culinary innovation : a systemic view." Thesis, University of Strathclyde, 2009. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=18262.

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3

Chen, Weiwei. "A coupled left ventricle and systemic arteries model." Thesis, University of Glasgow, 2015. http://theses.gla.ac.uk/7037/.

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Mathematical modelling and computational simulation are effective tools in studying the function of the cardiovascular system and diagnosing the progress of diseases in this system, especially when clinical experiments or measurements are limited or not capable to proceed. A variety of models have been developed related to different segments in the cardiovascular system, such as the heart, the valves, the systemic arteries and the pulmonary arteries, etc. Among these studies, modelling the left ventricle (LV) and systemic arteries (SA) have drawn a great deal of attention in the last several d

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4

Elidrissi, Imane <1991&gt. "applying Markov Chain switching model to Systemic Risk measures." Master's Degree Thesis, Università Ca' Foscari Venezia, 2015. http://hdl.handle.net/10579/6943.

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5

Drago, Leandro. "Non-systemic metamorphosis: millipede gonopods as a model system." Doctoral thesis, Università degli studi di Padova, 2009. http://hdl.handle.net/11577/3426455.

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Arthropod post-embryonic life is characterized by periodical moult cycles. These events are essential during individual growth, given that a rigid exoskeleton wraps them. When a moult event corresponds with a relatively sudden and conspicuous change in animal’s structure, is called metamorphosis; this phenomenon is characterized by a relatively high level of processes like apoptosis and cellular proliferation. For this reason, the study of the processes involved during metamorphosis has become a very important subject in evolutionary developmental biology (evo-devo) of arthropods. The principa

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6

FARINA, Gianluca. "Systemic risk measures and contagion models." Doctoral thesis, Università degli studi di Bergamo, 2014. http://hdl.handle.net/10446/30380.

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The main theme of the thesis is systemic risk measurement. This extremely young field of research has gained a lot of attention in recent times from academics and practioners alike because of global financial crises. The main contributions of the thesis can be grouped in four broad items. Firstly, we propose a novel categorization of the risk measures advanced in recent years based on the modeling assumptions they rely upon. We identified four categories: measures based on portfolio theory, econometric indicators, network analysis and measures based on multivariate default distribution. The

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7

Yau, C. "A systemic and dynamic model for project planning and control." Thesis, Lancaster University, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.370308.

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8

Kavvouras, Georgios. "A holistic systemic model for decision support in sustainable construction." Thesis, University of Nottingham, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.523692.

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9

Banda, Castro Ana Lilia, and Zamorano Miguel Arturo Morales. "Psychological Empowerment: A systemic model with individual and community components." Pontificia Universidad Católica del Perú, 2014. http://repositorio.pucp.edu.pe/index/handle/123456789/101236.

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This study aimed to confirm that social participation may influence empowerment as one ofthe four components explained by the theory. The hypothesis proposes systemic interaction of two components of empowerment: intrapersonal and behavioral. 113 urban residents participated in the study. The hypotheses were tested through the use of structural modeling. An intrapersonal component of empowerment, composed of positive empowerment, negative empowerment and socio-political control was identified. This component was affected by the behavioral component that involves social organization, community

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10

Ater, Steven L. "The interactive systemic approach an expansion of the biopsychosocial model /." Online full text .pdf document, available to Fuller patrons only, 2002. http://www.tren.com.

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11

Pham, Thi Hoa, and n/a. "Interrogative mood in English and Vietnamese : a systemic contrastive analysis." University of Canberra. Information Sciences, 1985. http://erl.canberra.edu.au./public/adt-AUC20060725.105609.

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The purpose of this study is to present a contrastive analysis of the different types of interrogative sentences in English and Vietnamese including their structures and meanings. It is also hoped that the result of this study will be of some use to English teachers in Vietnam in their classroom teaching and in their preparation of teaching materials. It may also be useful to Vietnamese students who are learning English, especially when learning the English interrogative mood. Hitherto, there have been different models of description of language, but the systemic model is considered to be one

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12

Reichert, Richard P. "A systemic model of leadership development for the church in Cuba." Online full text .pdf document, available to Fuller patrons only, 2003. http://www.tren.com.

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13

Glasscoe, Claire Anita. "Parental dysphoria following the diagnosis of cystic fibrosis : testing a systemic model." Thesis, University of Liverpool, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.399223.

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14

Stocks, M. R. "Experimental manipulation of autoimmunity in a mouse model of systemic lupus erythematosus." Thesis, Imperial College London, 1989. http://hdl.handle.net/10044/1/47675.

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15

Salameh, Sacha. "A perfusable vascularized full thickness skin model for topical and systemic applications." Thesis, Sorbonne université, 2019. http://www.theses.fr/2019SORUS466.

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De nombreux progrès ont déjà été réalisés pour développer des modèles de peau in vitro plus complexes et s’approchant de plus en plus du tissu in vivo. Cependant, la vascularisation reste l’un des défis à relever pour l’évolution des peaux reconstruites. Notre étude s'est concentrée sur le développement d'un équivalent de peau complète vascularisée et perfusée avec un réseau vasculaire plus complexe que les modèles déjà existants. Ainsi, nous avons combiné trois techniques : le moulage de la matrice, l’auto-assemblage des cellules endothéliales et la microfluidique. Ainsi, nous avons créé un é

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16

Mokbel, Rita. "Systemic risk in financial economic institutions." Thesis, Besançon, 2016. http://www.theses.fr/2016BESA2080.

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Les crises financières et les problèmes se formaient mais les indicateurs ne sont pas précis pour permettre une intervention réglementaire. La thèse propose un modèle dynamique pour le système bancaire avec une banque centrale afin de calculer un indicateur de faillite en fonction de la probabilité qu'une banque soit en faillite et les pertes rencontrées dans le réseau financier, une méthodologie qui peut améliorer la mesure, le suivi et la gestion du risque systémique.La thèse propose également des mécanismes de compensation : 1- avec un modèle considérant l'ancienneté du passif et avec un ty

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17

McAndrew, Paula. "Investigating casual conversation: a systemic functional linguistic and social network model of analysing social reality." Australia : Macquarie University, 2002. http://hdl.handle.net/1959.14/44619.

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"November 2001".<br>Thesis (PhD)--Macquarie University, Division of Linguistics and Psychology, Dept. of Linguistics, 2002.<br>Bibliography: p. 285-291.<br>Introduction -- Language from a systemic functional perspective -- Social networks: a review of literature relevant to the Scotland Island study -- Methodology -- Analysing relational ties: a social network perspective -- A systemic functional approach to analysing social reality -- Discussion and conclusion.<br>This research is concerned with the study of language and the social order. Working within the systemic functional theory of langu

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18

Fletcher, K. "A systemic model for a building performance and condition evaluation for primary schools." Thesis, University of Salford, 2018. http://usir.salford.ac.uk/46112/.

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19

Mäki-Petäjä, Kaisa Maria. "Inflammation, arterial stiffness and endothelial dysfunction : rheumatoid arthritis, a model of systemic inflammation." Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612095.

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20

Khoshbin, Espeed. "Extracorporeal membrane oxygenation for severe systemic inflammatory response : development of a rabbit model." Thesis, University of Leicester, 2008. http://hdl.handle.net/2381/29902.

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Hypothesis: ECMO is an acceptable supportive therapy for patients with severe SIRS despite triggering haematic response.;Objectives: To develop a reliable and reproducible animal model of SIRS to investigate strategies for reducing the haematic response.;Materials and Methods: Literature review: (I) The Systemic Thrombo-inflammatory Pathway (STIP). (II) The haematic response. Clinical studies: (I) Institutional review of ECMO for severe SIRS. (II) Comparative review of oxygenators performance. In-vivo studies: Animal experiments, (I) Development of a rabbit model of graded SIRS. (II) Dose resp

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21

O’Rourke, Simon. "An intelligence model for terrorist incident prevention for Australian police: A systemic investigation." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 2010. https://ro.ecu.edu.au/theses/379.

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This study examines the role that intelligence will continue to play in the ongoing efforts to mitigate the effects of contemporary terrorism. The role of domestic policing agencies is expanding to meet the challenge of transnational organised crime and also the threat to community safety and cohesion that terrorism entails. The September 11 attacks on the twin towers in New York city showcased the darkest elements of humanity whilst the courage personified by the police, firefighters and paramedics who entered the buildings to save others illuminated al that is best, in an event that was broa

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22

Washington, F. "Factors associated with resilience after paediatric injury : working towards a systemic model of resilience." Thesis, University of Liverpool, 2018. http://livrepository.liverpool.ac.uk/3026496/.

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23

Hillendahl, Gregory Manning. "A systemic model of the middle voice of the Greek of the New Testament." Theological Research Exchange Network (TREN), 1991. http://www.tren.com.

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24

Eversden, Stella. "Integrating systemic and school-based priorities into a curriculum model for secondary religious studies." Thesis, Eversden, Stella (1993) Integrating systemic and school-based priorities into a curriculum model for secondary religious studies. PhD thesis, Murdoch University, 1993. https://researchrepository.murdoch.edu.au/id/eprint/50548/.

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This study enquires about designing a curriculum model in religious education at secondary level (for ages approximately 14 upwards) which would seek to redress the problems inherent in existing models, and would aim to satisfy educational, systemic and school-based criteria in the religious education curricula of both government and non-government schools. A review of models in Britain, America, and Australia, and policies of school-based curriculum development and multiculturalism was conducted. The objective of "dialogical consciousness" was introduced, using cross-paradigm dialogue, which

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25

Torvell, Megan Isabel Lily. "Acute and chronic effects of systemic inflammation on P301S tau mouse model of neurodegeneration." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/29605.

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Systemic inflammation is thought to be an important driver in chronic neurodegeneration. During systemic infection, the inflammatory status of the periphery is communicated to the brain and conserved sickness behaviours initiated. However, in the context of dementia the same inflammatory stimulus might trigger delirium. Delirium is a severe, transient neuropsychiatric condition characterised by altered levels of arousal, inattention, cognitive deficits and psychoses. Delirium and systemic inflammation exacerbate the trajectory of pre-existing dementia, and are associated with increased risk of

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26

ALONGI, ALESSANDRA. "Development of a prognostic model for Macrophage Activation Syndrome in Systemic Juvenile Idiopathic Arthritis." Doctoral thesis, Università degli studi di Genova, 2020. http://hdl.handle.net/11567/1010555.

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Introduction: Macrophage activation syndrome (MAS) is a potentially life-threatening complication of systemic juvenile idiopathic arthritis (SJIA) characterized by heterogeneous organ involvement and severity. Early identification of patients at high risk of complicated clinical course may improve outcome by helping initiate prompt, appropriate immunosuppressive and supportive treatments. Yet, despite recent progress in clarifying the underlying immunological mechanisms, factors driving organ damage and severe outcome are not entirely understood, nor has the prognostic value of routinely gath

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27

Schrader, Lauran N. "Does ANA-positive SLE human serum promote development of Libman-Sacks endocarditis in the NP-SLE Lewis rat model?" Muncie, IN : Ball State University, 2009. http://cardinalscholar.bsu.edu/675.

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28

Roussignol, Nicolas. "Le "P3 systemic business model" : proposition d'une démarche collaborative de business modelling à l'heure de l'Anthropocène." Electronic Thesis or Diss., Université Paris sciences et lettres, 2024. http://www.theses.fr/2024UPSLD003.

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A l’heure de l’Anthropocène, les activités humaines ont eu plus que jamais un impact sur les écosystèmes planétaires. Si nous souhaitons vivre dans un espace juste et sûr pour l’humanité, les entreprises, majoritairement responsables et directement impactées par cette situation, doivent repenser leur manière de faire des affaires. Face à la complexité de ces enjeux et aux limites inhérentes de la pensée analytique pour y répondre, le concept de business model a ainsi besoin de mobiliser une pensée systémique. Au sein de la coopérative Biocoop, dans le cadre d’une recherche-action, nous avons é

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29

Huang, Yu-Hsing. "Having a New Pair of Glassess : Applying Systemic Accident Models on Road Safety." Doctoral thesis, Linköpings universitet, CSELAB - Cognitive Systems Engineering Laboratory, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-8189.

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The main purpose of the thesis is to discuss the accident models which underlie accident prevention in general and road safety in particular, and the consequences of relying on a particular model have for actual preventive work. The discussion centres on two main topics. The first topic is whether the underlying accident model, or paradigm, of traditional road safety should be exchanged for a more complex accident model, and if so, which model(s) are appropriate. From a discussion of current developments in modern road traffic, it is concluded that the traditional accident model of road safety

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30

Byler, Stefanie Lynn. "Systemic bacterial endotoxin plus MPTP as a model of Parkinson's disease in C57BL/J6 mice." Fort Worth, Tex. : Texas Christian University, 2007. http://etd.tcu.edu/etdfiles/available/etd-08302007-162100/unrestricted/byler.pdf.

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31

Lewis, Myles J. D. r. "The Effects of Autoimmunity on Atherosclerosis in a Novel Mouse Model of Systemic Lupus Erythematosus." Thesis, Imperial College London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.516784.

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32

Imani, Markid Maghsoud. "Balancism : a new legal and economic model for just distribution wealth and systemic financial stability." Thesis, King's College London (University of London), 2013. https://kclpure.kcl.ac.uk/portal/en/theses/balancism-a-new-legal-and-economic-model-for-just-distribution-wealth-and-systemic-financial-stability(a07c75dd-a15d-42b4-9e9c-6626ded2376c).html.

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The modern economic and financial systems have not so far secured a just and fair system of distribution of wealth and have frequently been exposed as containing systemic instabilities. In response, some think that there is no choice but to follow the laws and claims of Capitalism. Others have argued that it is time to revive and implement Socialism. Still others have voiced their support that the Islamic model would be the best solution. This thesis, which is an interdisciplinary and a comparative work, aims to suggest a new solution. The alternative system introduced in this research project

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33

Young, Anne Michelle. "A Systemic Model for Family Functioning: Mutual Influences of Spousal Attachment, Marital Adjustment, and Coparenting." Thesis, University of North Texas, 2017. https://digital.library.unt.edu/ark:/67531/metadc1011822/.

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The current study examined direct and indirect influences of romantic attachment processes, marital adjustment, and the coparenting relationship on family functioning. Data was collected from a community sample of 86 heterosexual couples with a child aged eight to eleven living in the home. Both spouses completed a demographic questionnaire, the Experiences in Close Relationships Scale, the Dyadic Adjustment Scale, the Coparenting Scale, and the Self-Report Family Inventory as part of a larger study on family processes in middle childhood. Data analysis included multilevel modeling, utilizin

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34

Clement, Priscillia. "High school dropout : systemic implications and the GED as a model of redress for dropouts /." View abstract, 2001. http://library.ccsu.edu/ccsu%5Ftheses/showit.php3?id=1639.

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Thesis (M.S.)--Central Connecticut State University, 2001.<br>Thesis advisor: Jane Fried. " ... in partial fulfillment of the requirements for the degree of Master of Science in School Counseling." Includes bibliographical references (leaves 75-80). Also available via the World Wide Web.

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35

Kristensen, Erik Kaergaard. "Systemic barriers to a future transformation of the building industry from a buyer controlled to a seller driven industry : an analysis of key systemic variables in the building industry, such as 'procurement model', 'buyer perception', 'production mode' and 'leadership and management', principally in a Danish development context and seen from the perspective of the architect." Thesis, Robert Gordon University, 2011. http://hdl.handle.net/10059/699.

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It has always been a ‘mystery’, why the Danish building industry stagnated after the industrial breakthrough, and never was able to adapt the industrial production, business culture, buyer perception, and leadership and management, used in nearly all other Danish industries. This study offers a new approach to understanding the problem - by analysing systemic barriers to the industry’s transformation to a seller driven industry, in the context of a widespread neglect of the need for industrialisation (a problem addressed by relatively little literature) with the building remaining a manual, cr

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36

Wu, Haijing, and 吴海竞. "The generation of tolerogenic dendritic cells in SLE and study of their mechanisms of action and therapeutic application in a lupus mouse model." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/206689.

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Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that is characterized by auto-reactive T and B lymphocytes and abundant auto-antibodies against nuclear components that form immune-complexes and lead to inflammation, organ dysfunction and failure. The current treatment for SLE includes corticosteroid and immunosuppressant agents which are associated with side effects. Immunotherapy such as tolerogenic dendritic cells (DCs) and regulatory T cells have potential therapeutic implications in autoimmune diseases. DCs are professional antigen presenting cells with important role i

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37

Patchev, Stephanie Anna. "The architecture and limbic activity patterns of rapid eye movement sleep as symptomatic and prognostic factors in an animal model of post-traumatic stress disorder." Diss., Ludwig-Maximilians-Universität München, 2014. http://nbn-resolving.de/urn:nbn:de:bvb:19-177784.

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38

Christoforidis, John Byron, Karen Briley, Katherine Binzel, et al. "Systemic Biodistribution and Intravitreal Pharmacokinetic Properties of Bevacizumab, Ranibizumab, and Aflibercept in a Nonhuman Primate Model." ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017. http://hdl.handle.net/10150/627123.

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PURPOSE. To determine the intravitreal pharmacokinetic properties and to study the systemic biodistribution characteristics of 1-124-labeled bevacizumab, ranibizumab, and aflibercept with positron emission tomography-computed tomography (PET/CT) imaging in a nonhuman primate model. METHODS. Three groups with four owl monkeys per group underwent intravitreal injection with 1.25 mg/0.05 mL 1-124 bevacizumab, 0.5 mg/0.05 mL 1-124 ranibizumab, or 2.0 mg/0.05 mL 1-124 aflibercept in the right eye of each subject. All subjects were imaged using PET/CT on days 0, 1, 2, 4, 8, 14, 21, 28, and 35. Serum

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39

Stikeleather, James A. "Toward a Systemic Model for Governance and Strategic Management: Evaluating Stakeholder Theory Versus Shareholder Theory Approaches." Scholar Commons, 2017. http://scholarcommons.usf.edu/etd/7092.

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The research’s intent is improvement in governance and strategic management initially by comparing Shareholder Theory and Stakeholder Theory and making results useful for both Practitioner and Academic audiences. A conceptual model for how a society establishes and evolves the roles it legitimizes for a business to support reasoning about those roles and the process originating the expectations, responsibilities, obligations, contributions and freedom to act in the roles is proposed. Understanding this process would enable better governance and strategic management of a fir

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40

Little, Mark Alan Pasha Matthew. "The role of anti-neutrophil cytoplasm antibodies in an experimental model of systemic small vessel vasculitis." Thesis, Imperial College London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.430867.

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41

Altaleb, Naderah. "Assessing the potential of rAAV9 systemic gene therapy for GM2 gangliosidoses using a Sandhoff mouse model." Nature Publishing Group, 2014. http://hdl.handle.net/1993/30287.

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The infantile GM2 gangliosidoses are severe neurodegenerative disorders, caused by a defect in the β-hexosaminidase system. They are characterized by lysosomal accumulation of the substrate, GM2 ganglioside, which results in severe neuronal damage and death in the early years of life. Sandhoff mice deficient in both major hexosaminidase isozymes, Hex A and Hex B, mimic the disease severity in the human condition including the motor deterioration, histopathological findings, and premature death. To investigate the utility of systemic adeno-associated virus 9 (AAV9)-based gene delivery in trea

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Mandelli, Andrea Paola. "Unfolding the immune response against Staphylococcus aureus-mediated systemic sequelae of skin recurrences." Doctoral thesis, Università di Siena, 2022. http://hdl.handle.net/11365/1203731.

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Staphylococcal protein A (SpA) is a surface-associated virulence factor of Staphylococcus aureus (S. aureus) which binds human immunoglobulins via both Fc and Fab fragment masking the pathogen to the host immune system. This activity interacts with the normal maturation of the host immune system during an infection and allows S. aureus to cause recurrent infections as, for example, skin recurrences. Skin recurrences are not only bothersome superficial infections that require continuous treatments, but may also evolve in more complicated and systemic complications. Immunization with SpA protec

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43

Daniels, Katherine Jean. "Couples' construction of meaning of an Alzheimer's disease diagnosis : a systemic approach." Diss., Manhattan, Kan. : Kansas State University, 2008. http://hdl.handle.net/2097/1057.

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Oliveira, Perla Novais de. "Transformação genética de tomate \'Micro-Tom\' com o gene enhanced disease susceptibility 5 (EDS5) isolado de Citrus sinensis." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/11/11144/tde-02022016-155536/.

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Nos anos recentes, a atividade agrícola da citricultura vem enfrentando grandes problemas fitossanitários, principalmente, com relação à viabilidade econômica decorrente do controle das doenças. A bactéria Candidatus Liberibacter spp. está associada ao HLB, a principal doença que limita a produção das plantas cítricas. Assim, muitos pesquisadores têm voltado suas atenções para estudarem e encontrarem genes-alvo na resposta do hospedeiro a este patógeno para utilização no melhoramento genético. Nesse sentido, métodos de transformação genética das plantas cítricas são essenciais, porém caracterí

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45

Galliano, Karin. "Children"s perceptions of marital conflict, parent-child relations and anxiety in children: a proposed systemic model." FIU Digital Commons, 1999. http://digitalcommons.fiu.edu/etd/3439.

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Few studies have examined the effects of a divorce on internalizing symptomatology in children, and none have done so in a clinic sample. The present study examined this issue in a clinic sample of children with anxiety disorders (aged 6-16). Because past research has found that it is not divorce but the child’s perspective of marital conflict that is the crucial factor in examining negative outcomes, it was hypothesized that children who reported worry about marital conflict would show greater internalizing symptomatology than those who reported no worries, regardless of whether they came fro

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46

Yasar, Muhammet Murat. "A Complex Systems Model for Understanding the Causes of Corruption: Case Study - Turkey." Thesis, University of North Texas, 2005. https://digital.library.unt.edu/ark:/67531/metadc4827/.

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It is attempted with this dissertation to draw an explanatory interdisciplinary framework to clarify the causes of systemic corruption. Following an intense review of political sciences, economics, and sociology literatures on the issue, a complex systems theoretical model is constructed. A political system consists of five main components: Society, interest aggregators, legislative, executive and private sector, and the human actors in these domains. It is hypothesized that when the legitimacy level of the system is low and morality of the systemic actors is flawed, selected political, social

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47

LEMOS, OLIVEIRA MENDONCA ROSANGELA MIRIAM. "Systemic Network Innovation and Its Application in the Brazilian Context of the "Estrada Real"." Doctoral thesis, Politecnico di Torino, 2014. http://hdl.handle.net/11583/2534088.

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ABSTRACT: The question that this work proposes to answer is already part of its title: “How to make ideas become a resource for social-economic improvement”. In order to approach an answer, a new strategy must be found, since this is a long lasting question, especially in contexts of developing countries with large social differences, such as Brazil. We have then started from the Systemic Design methodology which proposes the valorisation of the territory, people, relations and the optimization of resources. The application was set to be the Brazilian territory of the “Estrada Real”, on the s

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48

Hauff, Thomas R. "An assessment and application of the systemic linguistic model of verbal aspect in the New Testament proposed by Stanley E. Porter." Theological Research Exchange Network (TREN), 1996. http://www.tren.com.

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49

Griffin, Marley A. "A model for examining antinuclear antibody circulation and binding capabilities of human serum from systemic lupus erythematosus patients." Virtual Press, 2007. http://liblink.bsu.edu/uhtbin/catkey/1371840.

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Antinuclear antibodies (ANA) are used in screening and diagnosis of autoimmune connective tissue disorders including systemic lupus erythematosus (SLE). CNS related disorders are prevalent in SLE patients (–80%) and ANA binds specific sites within the brain. To investigate ANA infiltration across the blood-brain barrier (BBB), an ANA injectable Lewis rat model was created using 3 rat groups (saline, ANA, and ANA with histamine; since histamine promotes BBB permeability). ANA serum levels were tested for all three rat groups and rats injected with histamine demonstrated signs of histadelia. Bra

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Whibley, Natasha. "The role of effector and regulatory helper T cells in a murine model of systemic Candida albicans infection." Thesis, University of Aberdeen, 2013. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=192231.

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Abstract:

Diseases caused by fungi are increasing worldwide and are often associated with high mortality rates. In particular, the normally harmless commensal Candida albicans can cause serious disease if immunological and physiological barriers are perturbed, leading to systemic infection, which is fatal in up to 45% of cases. The adaptive immune response is believed to be important in protection against systemic candidiasis, however, the roles of different helper T (Th) cell subsets, particularly Foxp3+ regulatory T (Treg) cells, remain largely unexplored. The aims of this study were to adapt a mouse

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