Academic literature on the topic 'System of anaerobicaerobic bioreactors'

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Journal articles on the topic "System of anaerobicaerobic bioreactors"

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Al-Rayes, Aghyad W., Kerry A. Kinney, A. Frank Seibert, and Richard L. Corsi. "Load Dampening System for Vapor Phase Bioreactors." Journal of Environmental Engineering 127, no. 3 (March 2001): 224–32. http://dx.doi.org/10.1061/(asce)0733-9372(2001)127:3(224).

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FUNADA, Tadashi, Jiro HIRANO, Ron HASHIZUME, and Yukihisa TANAKA. "Development of Bioreactors for Water/Oil Heterogeneous System." Journal of Japan Oil Chemists' Society 41, no. 5 (1992): 423–27. http://dx.doi.org/10.5650/jos1956.41.423.

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Kitamura, Yutaka, Dan Paquin, Loren Gautz, and Tung Liang. "A rotational hot gas heating system for bioreactors." Biosystems Engineering 98, no. 2 (October 2007): 215–23. http://dx.doi.org/10.1016/j.biosystemseng.2007.07.005.

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Pavlou, Stavros. "Microbial competition in bioreactors." Chemical Industry and Chemical Engineering Quarterly 12, no. 1 (2006): 71–81. http://dx.doi.org/10.2298/ciceq0601071p.

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Competition for nutrients and other resources is an interaction common among microbial species growing together in the same environment. Such an environment can be created in the laboratory in a bioreactor in order to study this type of interaction and its effect on the microorganisms. Competition tends to eliminate species from the system. The main question then is whether the competing microbial species can coexist and under what conditions. The number of nutrients for which the microorganisms compete plays an important role, while periodic oscillations and spatial heterogeneity have a favorable effect on coexistence.
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Park, Jungsu, and Kerry A. Kinney. "Evaluation of Slip Feed System for Vapor-Phase Bioreactors." Journal of Environmental Engineering 127, no. 11 (November 2001): 979–85. http://dx.doi.org/10.1061/(asce)0733-9372(2001)127:11(979).

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Ferrero, Giuliana, Hector Monclús, Gianluigi Buttiglieri, Joaquim Comas, and Ignasi Rodriguez-Roda. "Automatic control system for energy optimization in membrane bioreactors." Desalination 268, no. 1-3 (March 2011): 276–80. http://dx.doi.org/10.1016/j.desal.2010.10.024.

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Cleland, N., and S. O. Enfors. "A biological system for studies on mixing in bioreactors." Bioprocess Engineering 2, no. 3 (1987): 115–20. http://dx.doi.org/10.1007/bf00387253.

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Thanapornsin, Thanawat, Likit Sirisantimethakom, Lakkana Laopaiboon, and Pattana Laopaiboon. "Effectiveness of Low-Cost Bioreactors Integrated with a Gas Stripping System for Butanol Fermentation from Sugarcane Molasses by Clostridium beijerinckii." Fermentation 8, no. 5 (May 8, 2022): 214. http://dx.doi.org/10.3390/fermentation8050214.

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The effectiveness of column bioreactors for butanol fermentation from sugarcane molasses by Clostridium beijerinckii TISTR 1461 was investigated. This fermentation was operated at an initial pH of 6.5 and temperature of 37 °C under anaerobic conditions. A 1-L bubble column bioreactor was used with various gas circulation rates ranging from 0.2 to 1.0 L/min. The highest butanol concentration (PB, 8.72 g/L), productivity (QB, 0.24 g/L∙h) and yield (YB/S, 0.21 g/g) were obtained with a gas circulation of 0.2 L/min. To improve butanol production efficiency, gas-lift column bioreactors with internal and external loops at 0.2 L/min of circulating gas were used. Higher PB (10.50–10.58 g/L), QB (0.29 g/L∙h) and YB/S (0.22–0.23 g/g) values were obtained in gas-lift column bioreactors. These values were similar to those using a more complex 2-L stirred-tank bioreactor (PB, 10.10 g/L; QB, 0.28 g/L h and YB/S, 0.22 g/g). Hence, gas-lift column bioreactors have potential for use as low-cost fermenters instead of stirred-tank bioreactors for butanol fermentation. When the gas-lift column bioreactor with an internal loop was coupled with a gas stripping system, it yielded an enhanced PB and sugar consumption of approximately 9% and 7%, respectively, compared to a system with no gas stripping.
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Sarazen, Jillian C., Joshua W. Faulkner, and Stephanie E. Hurley. "Evaluation of Nitrogen and Phosphorus Removal from a Denitrifying Woodchip Bioreactor Treatment System Receiving Silage Bunker Runoff." Applied Sciences 10, no. 14 (July 12, 2020): 4789. http://dx.doi.org/10.3390/app10144789.

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Leachate and storm-driven runoff from silage storage bunkers can degrade receiving water bodies if left untreated. This study evaluated a novel treatment system consisting of three treatment tanks with a moving-bed biofilm reactor and paired side-by-side denitrifying woodchip bioreactors for the ability to reduce influent nutrient mass loads. Flow-based samples were taken at four locations throughout the system, at the inflow to the first tank, outflow from the tanks prior to entering the woodchip bioreactors, and from the outflows of both bioreactors. Samples were analyzed for concentrations of nitrogen (N) and phosphorus (P) species. Inflow concentrations were reduced from the bioreactor outflows by an average of 35% for total N (TN) and 16% for total P (TP) concentrations on a storm event basis. The treatment system cumulatively removed 76% of the TN mass load, 71% of the nitrite + nitrate-N (NO2−+NO3−-N) load, 26% of the TP mass load, and 19% of the soluble reactive P load, but was a source of ammonium-N, based on the monitoring of 16 storm events throughout 2019. While the system was effective, very low NO2−+NO3−-N concentrations in the silage bunker runoff entered the bioreactors, which may have inhibited denitrification performance.
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Arshi, Simin, Mehran Nozari-Asbemarz, and Edmond Magner. "Enzymatic Bioreactors: An Electrochemical Perspective." Catalysts 10, no. 11 (October 24, 2020): 1232. http://dx.doi.org/10.3390/catal10111232.

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Biocatalysts provide a number of advantages such as high selectivity, the ability to operate under mild reaction conditions and availability from renewable resources that are of interest in the development of bioreactors for applications in the pharmaceutical and other sectors. The use of oxidoreductases in biocatalytic reactors is primarily focused on the use of NAD(P)-dependent enzymes, with the recycling of the cofactor occurring via an additional enzymatic system. The use of electrochemically based systems has been limited. This review focuses on the development of electrochemically based biocatalytic reactors. The mechanisms of mediated and direct electron transfer together with methods of immobilising enzymes are briefly reviewed. The use of electrochemically based batch and flow reactors is reviewed in detail with a focus on recent developments in the use of high surface area electrodes, enzyme engineering and enzyme cascades. A future perspective on electrochemically based bioreactors is presented.
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Dissertations / Theses on the topic "System of anaerobicaerobic bioreactors"

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Козар, Марина Юріївна. "Розробка технології біологічного очищення стічних вод від сполук фосфору в системі анаеробно-аеробних біореакторів." Doctoral thesis, Київ, 2014. https://ela.kpi.ua/handle/123456789/8673.

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Ferrero, Giuliana. "Development of an air-scour control system for membrane bioreactors." Doctoral thesis, Universitat de Girona, 2011. http://hdl.handle.net/10803/32202.

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The thesis involves the development and implementation of a new and robust control system based on permeability trends but at the same time capable of reducing aeration proportionally to permeate flux. Permeability was made a key parameter for directly comparing temporary changes in membrane performance. Transmembrane pressure and flux were gathered every 10 seconds and permeability values were automatically calculated; different mathematical algorithms were applied for the signal filtering of on-line data. Short term and long term permeability trends were compared once a day, and a control action was applied proportionally to the short term/long term permeability ratio without exceeding the aeration flow recommended by the membrane suppliers.
El treball presentat a la tesi inclou el desenvolupament i la implementacio d’un nou sistema de control robust basat en les tendencies de la permeabilitat i, al mateix temps, capac de reduir l’aeracio de forma proporcional al flux de permeat. S’ha seleccionat la permeabilitat com el parametre clau per comparar directament els canvis temporals en el funcionament de les membranes. La pressio transmembrana i el flux es mesuren cada 10 segons i llavors la permeabilitat es calcula automaticament. El senyal de les dades recollides en linia es filtra adequadament mitjancant diversos algoritmes matematics. L’algoritme de control compara diariament una tendencia a curt termini de la permeabilitat amb una tendencia a llarg termini de la permeabilitat, i s’aplica una accio de control proporcional al quocient de les dues tendencies, sense excedir mai el cabal d’aeracio recomanat pels fabricants de membranes.
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Ntwampe, Seteno Karabo Obed. "A perfluorocarbon-based oxygen delivery system to a membrane bioreactor." Thesis, [S.l. : s.n.], 2009. http://dk.cput.ac.za/cgi/viewcontent.cgi?article=1059&context=td_cput.

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Jamaleddine, Eyad. "Composting bioreactors: heat redistribution and heat recovery system for small compost vessels." Thesis, McGill University, 2014. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=123122.

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Composting is an increasingly popular method of municipal and residential waste management. Uniform composting is necessary to obtain a consistent product and to ensure the destruction of pathogens. It requires that a homogeneous temperature be maintained throughout the compost. To accomplish this, a compost vessel with a heat redistribution system (HRS) was designed, constructed and tested. This system was composed of a heat exchanger, plastic tubing and a copper coil filled with water. The system moved heat from the warmer center of the compost bed to the cooler areas at the outside and bottom of the bed without external inputs of energy. Once composting began, the temperature of the water inside the heat exchanger increased and buoyancy effects caused the water to flow through the copper tubing, distributing the core heat throughout the compost. Heat was also redistributed by conduction along the copper tubing. The HRS can be used in applications requiring assurance of uniform composting conditions and a high-quality product. Previously obtained test data suggested that the HRS system accomplished its goal, but high amounts of heat loss occurred through the four-inch exhaust vent. An air heat exchanger (AES) was added to reduce heat loss from the top aeration vent. A total of twelve experiments were run: four with the HRS, four with the AES and four controls. The vessels were fitted with thermocouples at 33, 54 and 84 cm from the bottom. The HRS vessels demonstrated higher temperatures during the first 10 days of the experiment (p<0.001).
Le compostage est une méthode de plus en plus populaire pour la gestion municipale et résidentielle des déchets. Le compostage uniforme est nécessaire pour obtenir un produit homogène de haute qualité et assurer la destruction des agents pathogènes. Il est donc essentiel de maintenir une température uniforme dans tout le compost. Pour mieux y parvenir, un récipient de compost équipé d'un système de redistribution de la chaleur (HRS) a été conçu, construit et vérifié. Ce système est composé d'un échangeur de chaleur, un tube en plastique, et une bobine de cuivre rempli d'eau. La digestion bactérienne des matières organiques cause une augmentation de la température de l'eau à l'intérieur du HRS et provoque un effet de flottabilité qui enchaîne un déplacement d'eau à l'intérieur du tube de cuivre, distribuant la chaleur du centre le plus chaud du compost vers les zones plus froides et ce, sans apport d'énergie externe. La chaleur est également redistribuée par conduction le long du tube de cuivre. Les résultats obtenus suggèrent que le HRS atteint son objectif, mais des pertes de chaleur ont été découvertes à la sortie d'air de 4 ̎. Un échangeur de chaleur à air (AES) a été ajouté pour réduire la perte de chaleur. Un total de douze expériences ont été effectuées : quatre avec le HRS, quatre avec l'AES et quatre contrôles. Les vaisseaux été équipés de thermocouples placés à 33, 54 et 84 cm du sol. Les vaisseaux équipés du HRS ont démontré des températures plus élevées au cours des 10 premiers jours de l'expérience (p < 0,001).
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Monclús, Sales Hèctor. "Development of a decision support system for the integrated control of membrane bioreactors." Doctoral thesis, Universitat de Girona, 2011. http://hdl.handle.net/10803/78922.

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The work presented in this PhD thesis includes various partial studies aimed at developing a decision support system for membrane bioreactor integrated control. The decision support systems (DSS) have as a main goal to facilitate the operation of complex processes due to the multiple variables that are processed. For this reason, the research used has focused on aspects related to nutrient removal, and on the development of indicators or sensors capable of facilitating, automating and controlling the filtration process in an integrated way with the biological processes that taking place. Work has also been done on the design, development, implementation and validation of tools based on the knowledge made available by the automatic control and the supervision of the MBRs
El treball presentat en aquesta tesi doctoral inclou diversos estudis parcials amb l’objectiu final de desenvolupar un sistema d’ajuda a la decisió pel control integrat dels bioreactors de membrana. Els sistemes d’ajuda a la decisió, SAD o DSS de l’anglès, decision support system, tenen com a objectiu facilitar l’operació de processos complexes degut a multitud de variables de procés. Per aquest motiu, la recerca realitzada s’ha centrat en aspectes relacionats amb l’eliminació de nutrients, i en el desenvolupament d’indicadors o sensors pel procés de filtració capaços d’integrar-se amb els processos biològics que hi tenen lloc. També s’ha treballat en el disseny, desenvolupament, implementació i validació d’eines basades en el coneixement que facilitin el control automàtic i la supervisió dels MBR mitjançant un DSS.
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Ronne, Luke John Thomas. "Design considerations and analysis of a bioreactor for application in a bio-artificial liver support system." Pretoria : [s.n.], 2006. http://upetd.up.ac.za/thesis/available/etd-04242008-093504/.

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Mamo, Julian. "Assessment and optimisation of the operation of integrated membrane system for wastewater reclamation." Doctoral thesis, Universitat de Girona, 2018. http://hdl.handle.net/10803/667844.

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The combination of two membrane technologies coupled together in series has become a standard technology when it comes to producing reclaimed water of high quality for potable reclamation or industrial applications. This combination of two membrane processes is referred to as integrated membrane systems (IMS). Despite the widespread experience gained utilizing such a process technology around the world, there are a number of aspects of the process technology which require further investigation including the fate of compounds of emerging concern (CEC), the control of N-Nitrosodimethylamine (NDMA) formation, the use of energy associated with the process and the total cost of producing the reclaimed water, and monitoring membrane integrity in RO treatment processes. The objective of this work was to further the knowledge in one aspect related to each of these four challenges and then bring each of these areas together in the discussion to understand whether proposing a decision support system for the online monitoring and operation of integrated systems would allow improvements to the current state-of-the-art.
La combinació de dos tecnologies de membrana acoblades en sèrie ha esdevingut un tecnologia consolidada degut a la capacitat de produir aigua d’elevada qualitat i potencialment reutilitzable per aplicacions industrials com fins i tot per ser potabilitzada. Tot i l’elevada experiència adquirida en aquests processos combinats, encara hi ha aspectes del procés que calen una investigació més profunda que inclogui el coneixement sobre l’eliminació dels compostos emergents, el control de la formació de N-Nitrosodimetilamines (NDMA), l’ús de l’energia associada amb el procés incloent el cost total de produir l’aigua reutilitzable, i el seguiment de la integritat de la membrana en el tractament amb osmosi inversa (OI). L’objectiu d’aquest treball recau en avançar en el coneixement dels aspectes relacionats amb cada un dels quatre reptes esmentats, per aconseguir discutir de forma conjunta la millor forma d’integrar aquest nou coneixement adquirit proposant un sistema d’ajuda a la decisió pel control i seguiment de l’operació de sistemes integrats de membrana (SIM).
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Porter, Blaise Damian. "Development and application of a 3-D perfusion bioreactor cell culture system for bone tissue engineering." Diss., Available online, Georgia Institute of Technology, 2005, 2005. http://etd.gatech.edu/theses/available/etd-11222005-174526/.

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Thesis (Ph. D.)--Mechanical Engineering, Georgia Institute of Technology, 2006.
Wick, Tim, Committee Member ; Neitzel, Paul, Committee Member ; Fyhrie, David, Committee Member ; Garcia, Andres, Committee Member ; Guldberg, Robert, Committee Chair. Vita.
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Cui, Na. "Development of a system of small pressurizable bioreactors used to assess Saccharomyces cerevisiae's behaviour under CO₂ and O₂ pressure." Thesis, université Paris-Saclay, 2020. http://www.theses.fr/2020UPASC038.

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Les domaines d'application de la levure sont vastes, allant de la nourriture, de la brasserie à l'énergie verte. La levure Saccharomyces cerevisiae est l'espèce dominante à l’échelle mondiale. En outre, S. cerevisiae est également un organisme modèle important dans la recherche sur la biologie cellulaire moderne et est l'un des micro-organismes eucaryotes les plus étudiés.Ce travail se concentre sur le comportement des cultures de levures exposées à la pression induite par le CO₂ et l'O₂. La pression maximale étudiée est de 9 bar (A) car la pression la plus élevée pouvant être atteinte dans les bioréacteurs à l'échelle industrielle est de 8 bar (A). Afin d'exposer la culture de levure à des conditions de pression, de nouveaux bioréacteurs ont été construits et caractérisés. Deux expériences sont conçues : des expériences pour étudier la croissance des levures et des métabolites sous pression, ainsi que les expériences de biologie moléculaire pour mieux comprendre le comportement des cellules de levures sous différentes pressions d'O₂.La première expérience a permis de mieux comprendre l'influence des pressions de CO₂ et O₂ sur le comportement de culture de S. cerevisiae. En ce qui concerne l’impact du CO₂, l'étude a montré que la culture de levure a des comportements constants sous différentes pressions. Alors qu'en termes de pression O₂, sous 2 à 5 bars (A) de pression atmosphérique, les cellules de levure présentent des taux de croissance plus élevés par rapport à la pression atmosphérique. De plus, le glutathion moléculaire antioxydant a maintenu un équilibre redox. En dessous de 6 à 9 bars (A), la croissance cellulaire est inhibée et 9 bars (A) entraînent une accumulation excessive de glutathion oxydé.D'un autre côté, l'expérience moléculaire a permis de mieux comprendre le comportement de la culture sous les pressions d'O₂. L'étude de plusieurs gènes induits par le stress oxydatif a mis en évidence les effets cellulaires du stress oxydatif et la réponse des mécanismes moléculaires dans les cellules de levure. Il a été démontré que plusieurs gènes induits par le stress oxydatif étaient régulés à la hausse : le gène du facteur de transcription Msn2/4 et Yap 1, les gènes du métabolisme du glutathion GSH2 et GLR, ainsi qu'un gène de synthèse de la superoxyde dismutase SOD2
Yeast fields of application are extensive, ranging from food, brewing to green energy. The yeast Saccharomyces cerevisiae is the worldwide dominating species. In addition, S. cerevisiae is also an important model organism in modern cell biology research and is one of the most thoroughly studied eukaryotic microorganisms.This work focuses on the behaviour of yeast culture exposing to pressure induced by CO2 and O2. The pressure is set up to 9 bar (A) due to the highest pressure can be reached in industrial scale bioreactors is 8 bar (A). In order to expose yeast culture to pressure conditions, new bioreactors were built and characterised. Two experiments are designed: an experiment to investigate the yeast growth and the metabolites under pressure, as well as the molecular biology experiments to better understand yeast cells behaviour under various O₂ pressure.The first experiment has offered a better understanding of the influence of CO₂ and O₂ pressures on S. cerevisiae culture behaviour. Regarding the impact of CO₂, the study has shown that the yeast culture has consistent behaviours under different pressures. While, in terms of O₂ pressure, under 2 to 5 bar (A) air pressure, yeast cells show higher growth rates compared with atmospheric pressure. Furthermore, the antioxidant molecular glutathione kept a redox balance. Under 6 to 9 bar (A), the cells growth is inhibited and 9 bar (A) leads to the excessive oxidised glutathione accumulation.On the other hand, the molecular experiment has derived further insights on the culture behaviour under O2 pressures. The investigation of several oxidative stress induced genes has highlighted the cellular effects of oxidative stress induced by oxygen pressure and molecular mechanisms of oxidative stress response in yeast cell. It was shown that several oxidative stress induced genes were upregulated: transcription factor gene Msn2/4 and Yap 1, glutathione metabolism genes GSH2 and GLR, as well as a superoxide dismutase synthesis gene SOD2
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Deladisma, Marnico David. "Accuracy and Enhancement of the Lattice Boltzmann Method for Application to a Cell-Polymer Bioreactor System." Diss., Georgia Institute of Technology, 2006. http://hdl.handle.net/1853/10546.

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Articular cartilage has a limited ability to heal due to its avascular, aneural, and alymphatic nature. Currently, there is a need for alternative therapies for diseases that affect articular cartilage such as osteoarthritis. Recently, it has been shown that tissue constructs, which resemble cartilage in structure and function, can be cultured in vitro in a cell-polymer bioreactor system. Bioreactors provide a three dimensional environment that promotes cell proliferation and matrix production. The primary objective of this study is to accurately simulate fluid mechanics using the lattice Boltzmann method for application to a cell-polymer bioreactor system. Lattice Boltzmann (LB) is a flexible computation technique that will allow for the simulation of a moving construct under various bioreactor conditions. The method predicts macroscopic hydrodynamics by considering virtual particle interactions. Derived from the Lattice Gas Automata, lattice Boltzmann allows for mass transfer, complex geometries, and particle dynamics. A primary goal is to characterize the accuracy of the LB implementation and eventually the shear stresses felt by a tissue construct in this dynamic environment. This information is important since recent studies show that chondrocytic function may depend on the mechanical stimuli produced by fluid flow. Hence, shear stress may affect the final mechanical properties of tissue constructs. In this study, numerical simulations are done first in 2D and then extended to 3D to test the LB implementation. Simulations of the rotating wall vessel (RWV) bioreactor are then undertaken. The results are benchmarked against computations done with a commercial CFD package, FLUENT, and compared with analytic solutions and experimental data.
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Books on the topic "System of anaerobicaerobic bioreactors"

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1949-, Asenjo Juan A., and Merchuk José C. 1938-, eds. Bioreactor system design. New York: M. Dekker, 1995.

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Asenjo, Juan A. Bioreactor System Design (Biotechnology and Bioprocessing Series). CRC, 1994.

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R, Pellis Neal, and United States. National Aeronautics and Space Administration., eds. Utilization of microgravity bioreactor for differentiation and growth of human vascular endothelial cells: Final report. [Washington, DC: National Aeronautics and Space Administration, 1997.

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Book chapters on the topic "System of anaerobicaerobic bioreactors"

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von Meien, Oscar F., Luiz F. L. Luz, J. Ricardo Pérez-Correa, and David A. Mitchell. "Design of the Air Preparation System for SSF Bioreactors." In Solid-State Fermentation Bioreactors, 403–12. Berlin, Heidelberg: Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/3-540-31286-2_29.

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Eibl, Regine, Nina Steiger, Sabine Wellnitz, Tiago Vicente, Corinne John, and Dieter Eibl. "Fast Single-Use VLP Vaccine Productions Based on Insect Cells and the Baculovirus Expression Vector System: Influenza as Case Study." In Disposable Bioreactors II, 99–125. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/10_2013_186.

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Shimizu, K. "An overview on the control system design of bioreactors." In Measurement and Control, 65–84. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/bfb0007387.

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Satapathy, Monalisa, Aparna Yadu, J. Anandkumar, and Biju Prava Sahariah. "Bioreactors for Degradation of Toxic Pollutant in Wastewater System." In Sustainable Technologies for Water and Wastewater Treatment, 275–96. First edition. | Boca Raton, FL : CRC Press, 2021.: CRC Press, 2021. http://dx.doi.org/10.1201/9781003052234-19.

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Mazzei, Rosalinda, Emma Piacentini, Enrico Drioli, and Lidietta Giorno. "Membrane Bioreactors for Green Processing in a Sustainable Production System." In Process Intensification for Green Chemistry, 227–50. Chichester, UK: John Wiley & Sons, Ltd, 2013. http://dx.doi.org/10.1002/9781118498521.ch8.

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Kirch, Heinz J., Cynthia Sheffield, and John R. DeLoach. "Susceptibility of Carrier Erythrocytes to a Natural Hemolytic System." In The Use of Resealed Erythrocytes as Carriers and Bioreactors, 341–45. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3030-5_41.

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Chiarantini, Laura, and John R. DeLoach. "Standardization of an Encapsulation System: A Method to Remove Fragile Cells." In The Use of Resealed Erythrocytes as Carriers and Bioreactors, 55–62. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3030-5_7.

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Kravtzoff, Roger, Eric Urvoase, Catherine Chambon, and Claude Ropars. "Gd-DOTA Loaded into Red Blood Cells, a New Magnetic Resonance Imaging Contrast Agents for Vascular System." In The Use of Resealed Erythrocytes as Carriers and Bioreactors, 347–54. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3030-5_42.

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Thompson, Christine M., Johnny Montes, Marc G. Aucoin, and Amine A. Kamen. "Recombinant Protein Production in Large-Scale Agitated Bioreactors Using the Baculovirus Expression Vector System." In Methods in Molecular Biology, 241–61. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-3043-2_11.

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Elias, Cynthia B., Barbara Jardin, and Amine Kamen. "Recombinant Protein Production in Large-Scale Agitated Bioreactors Using the Baculovirus Expression Vector System." In Baculovirus and Insect Cell Expression Protocols, 225–45. Totowa, NJ: Humana Press, 2007. http://dx.doi.org/10.1007/978-1-59745-457-5_11.

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Conference papers on the topic "System of anaerobicaerobic bioreactors"

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Rudek, F., B. L. Nelsen, T. Baselt, T. Berger, M. Wiele, I. Prade, and P. Hartmann. "Non-disruptive measurement system of cell viability in bioreactors." In SPIE BiOS, edited by Daniel L. Farkas, Dan V. Nicolau, and Robert C. Leif. SPIE, 2016. http://dx.doi.org/10.1117/12.2211545.

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Menisher, Tewodros, Mohamad Metghalchi, and Edgar B. Gutoff. "Mixing Studies in Bioreactors." In ASME 1997 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1997. http://dx.doi.org/10.1115/imece1997-0232.

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Abstract Fluid mixing is a very important factor that needs to be considered in the design of bioreactors. Growing cells in bioreactors require sufficient amounts of nutrients and oxygen for their growth. The transfer of these nutrients to the cells can be ensured by sufficient mixing, yet excessive shear can destroy the cells. This study compares two impellers used for mixing: the “Dumbo Ear” impeller and the high efficiency A310 impeller. Mixing time is used as the criteria of the performance of the impellers. Mixing time is defined as the time taken for the disappearance of the pink color of Phenolphthalein indicator in a basic solution by the rapid addition of acid. A known amount and concentration of sodium hydroxide is added to a bioreactor containing distilled water with a known amount phenolphthalein, turning the solution pink. Using pressure driven dispensing system (Figure 1), excess hydrochloric acid is rapidly injected to neutralize the base. The time it takes for the solution to become colorless is recorded as the mixing time. The mixing time is measured as a function of rotational speed for different locations of the impeller. The results are reported in figures 2–6. Figure 2 compares Dumbo Ear impeller with the A310 at a clearance-to-height ratio (C/H) of 0.44 for a vertically centered shaft. In all the cases studied, the Dumbo Ear impeller out-performed the A310. The effect of varying clearance of the impeller on the mixing time was also investigated. Unlike the A310, the Dumbo Ear impeller showed better mixing as the clearance is reduced (Figure 3). In studying the effect of shaft angle on mixing time, two ways of pivoting the impeller were utilized. In the first case the impeller was pivoted at the intersection of the tank centerline with the top surface of the liquid. The impeller was also pivoted so as to maintain the bottom of the impeller shaft at the centerline of the tank. Thus in one case the impeller shaft entered the liquid at the centerline of the tank, and in the other case it did not, but the base of the shaft remained at the centerline. The shear forces will be different in the two cases because the clearances will be different. Figure 4 shows the variation in mixing time for a 15° shaft angle. In most of the cases studied, pivoting at the surface of the liquid gives a shorter mixing than pivoting at bottom of the impeller shaft. Figures 5 & 6 compare the mixing times for vertical and pivoted impellers for the two types of pivoting. In both types, tilting impeller reduces the mixing time. This mixing study showed that in most cases, at the same rotational speeds, the Dumbo Ear impeller gave shorter mixing times than the A310. Also, tilting the Dumbo Ear impeller and having a small bottom clearance gave the shortest blending times. However, in all cases, one has to consider the increased shear forces on cells when clearance between the blades to the walls is reduced.
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Van Dyke, W. Scott, Eric Nauman, and Ozan Akkus. "A Novel Mechanical Bioreactor System Allowing Simultaneous Strain and Fluid Shear Stress on Cell Monolayers." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53595.

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The causes, mechanisms, and biology of bone adaptation have been under intense investigation ever since Julius Wolff proposed that bone architecture is determined by mathematical laws as a result of mechanical loading. How bone responds to mechanical loads by converting the mechanical signals into chemical signals is known as mechanotransduction. The in vivo environment of bone is complex, and most studies of cell-level phenomena have relied on the use of in vitro experiments using mechanical bioreactors. The main types of bioreactors are fluid flow shear stress, tensile and/or compressive strain, and hydrostatic pressure [1–2]. Of these bioreactors, the most intuitive mechanical stimulus for bone would be the tensile and compressive strain bioreactors. However, many researchers now claim that shear stress via interstitial fluid flow in the lacunar-canalicular porosity is the primary mechanosensory stimulus [3]. A handful of studies have attempted to compare the effects of both of these mechanical stimuli on osteoblasts, but these studies are lacking in two respects [4–6]. First, if both fluid flow and strain are performed in the same bioreactor, the magnitude of one loading mode is explicitly determined through constitutive equations, while the other is only estimated. Second, if the magnitudes of the loading modes are able to be explicitly determined they are performed in different bioreactors, providing the cells different extracellular environments. Therefore, a highly controllable dual-loading mode mechanical bioreactor, as described and characterized in this study, is a necessary tool to further understand the mechanotransduction of bone.
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Petre, Emil, and Vladimir Rasvan. "On some basic theory aspects for robust-distributed parameter bioreactors." In 2015 19th International Conference on System Theory, Control and Computing (ICSTCC). IEEE, 2015. http://dx.doi.org/10.1109/icstcc.2015.7321328.

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Leibold, C., M. Wahalla, C. Blume, H. Blume, and M. Wilhelmi. "A real-time monitoring system controller for medical tissue engineering bioreactors." In 2015 IEEE International Conference on Consumer Electronics (ICCE). IEEE, 2015. http://dx.doi.org/10.1109/icce.2015.7066310.

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Liu, Bo, Ming Chen, and Tao Chi. "Application of wireless sensor network based on ZigBee technology in photo-bioreactors system." In 2012 International Conference on Graphic and Image Processing, edited by Zeng Zhu. SPIE, 2013. http://dx.doi.org/10.1117/12.2002299.

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Cantero, Katty M., and Marco E. Sanjuan. "Dynamic Model Fuzzy Transition in DMC Type Controllers for Varying Dynamics in Bioreactors." In ASME 2008 International Mechanical Engineering Congress and Exposition. ASMEDC, 2008. http://dx.doi.org/10.1115/imece2008-67471.

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This research presents an approach to implement industrial type DMC (Dynamic Matrix Control) controllers in biological process where a fed-batch operation is required. In this type of operation a substantial change in the process dynamics occurs due to changes in volume, reaction rate, pressure, temperature, concentration, and other process variables. To compensate for changes in the dynamic, several matrix models are identified, and using a fuzzy supervisor a soft model transition is implemented, such that the controller and the process performance can adapt to the new operating conditions without affecting the process integrity. The control system design, its identification, and implementation are presented, focusing in the articulation between MPC (Model Predictive Control) and Fuzzy Supervision. The overall strategy is demonstrated at a simulation level using a benchmark fermentation process for Penicillin production in Fed-Batch mode. In this process glucose is used as a substrate, and a fungus, penicillium chrysogenum, is used in a fed-batch reactor to obtain penicillin. The model presents an unstructured approach to the reactor dynamic system, and the initial steps for this research required the development of an identification procedure for such zones.
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Nwaigwe, Kevin N., Nnamdi V. Ogueke, Chibuike Ononogbo, and Emmanuel E. Anyanwu. "Performance Study of Anaerobic Digestion of Organic Municipal Waste in Upflow Bioreactor With Central Substrate Dispenser." In ASME 2013 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/imece2013-64064.

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A performance study of anaerobic digestion of organic municipal waste in upflow bioreactor with central substrate dispenser is presented. The experimental rig is based on an integrated system of bioreactors consisting of Upflow Bioreactor (UB), Upflow Bioreactor with Central Subtrate Dispenser (UBCSD), and Continous Stirred Tank Reactor (CSTR) each having internal volume of 76 litres, 64.8 litres, and 76 litres respectively. The scheme is used for minimizing the mixing and fouling problems associated with some conventional bioreactors during digestion reaction. Organic municipal waste (OMW) was used to prepare the slurry for the reactors. Microbial reaction was enhanced during operation using a measured quantity (2kg) of substances from the rumen of a newly slaughtered cow. The experimentation from feeder tank to Bioreactors was carried out for a period of 10-days Hydraulic Retention Time (HRT) at 37°C. Effects of some basic parameters affecting anaerobic digestion in terms of biogas production and Chemical Oxygen Demand (COD) reduction were carried out. They include substrate temperature, minimal average temperature, changes in temperature, substrate content and properties, available nutrient, retention time, organic loading rate, pH level, nitrogen inhibition and C/N ratio, substrate agitation, and inhibitory factors. Results showed that UBSCD generated the highest level of Biogas yield of up to 52915 ml, while UB and CSTR yielded 23550ml and 28980ml respectively. Similarly for COD removal, 24343 mg/l, 5775.4 mg/l, and 23155 mg/l were achieved for UBCSD, UB and CSTR respectively from an initial value of 120,320 mg/l. These results show that the use of UBCSD better enhances biofuel production from organic municipal waste.
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Alimberti, Richard, Vedang Chauhan, and Devina Jaiswal. "Bioreactor Temperature Control System Using PID Controller." In ASME 2021 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/imece2021-71715.

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Abstract Bioreactors are engineered physiological environment that can be used to study and grow tissue and organ systems in vitro. They are used to subject the cells to physiologically relevant stimulus such as tensile or compressive stress, bending, torsion or fluid flow. An optimal internal environment of a bioreactor should remain sterile while maintaining the viability of tissue, cells and biomolecules at 37°C (normal body temperature) with a tolerance of + or −0.1 °C. This study presents an Arduino microcontroller-based temperature-controlled system using an autotuning proportional integral derivative (PID) control for a small-scale bioreactor. A table top bioreactor temperature control system was designed, fabricated and assembled with laser cut acrylic enclosure. The closed-loop control system maintained the set temperature of 37°C using a tuned PID controller that used a high precision TMP117 sensor for feedback, and controlled the heating element accordingly. The system achieved the desired performance characteristics such as a fast rise time, settling time, low overshoot and low steady state error. Once the system achieved the steady state, it maintained the temperature at 37 ± 0.1 °C. Since the temperature control can vary and monitor fine changes in the environment, the system can be used to study an impact of temperature variations on cell response such as growth and differentiation.
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Kortsmit, Jeroen, Niels J. B. Driessen, Marcel C. M. Rutten, and Frank P. T. Baaijens. "Non Invasive Assessment of Leaflet Deformation in Heart Valve Tissue Engineering." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-175643.

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Contemporary tissue engineered heart valves seem to have sufficient mechanical strength for implantation [1]. Nevertheless, mechanical properties, tissue structure and architecture still need to be improved. Recent studies indicate enhancement of mechanical properties by applying cyclic diastolic pressure loads to the developing tissue in a bioreactor system [2]. However, current bioreactors operate with a preset transvalvular pressure applied to the tissue. Mechanical properties of the engineered construct may vary during culturing and consequently, the pressure-induced deformations are unknown. To systematically study the effects of mechanical straining on tissue development and to design an optimal conditioning protocol, real-time measurement and control of local tissue strains are desired.
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Reports on the topic "System of anaerobicaerobic bioreactors"

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Hoover, Natasha L., and Michelle L. Soupir. Experimental Tile Drainage Denitrification Bioreactors: Pilot-Scale System for Replicated Field Research. Ames: Iowa State University, Digital Repository, 2017. http://dx.doi.org/10.31274/farmprogressreports-180814-1738.

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