Relevant bibliographies by topics / Synthesis of cyclopropanes

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Synthesis of cyclopropanes'

Author: Grafiati
Published: 4 June 2021
Last updated: 14 February 2022

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Journal articles on the topic "Synthesis of cyclopropanes"

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Craig, Alexander J., and Bill C. Hawkins. "The Bonding and Reactivity of α-Carbonyl Cyclopropanes." Synthesis 52, no. 01 (October 1, 2019): 27–39. http://dx.doi.org/10.1055/s-0039-1690695.

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The cyclopropane functionality has been exploited in a myriad of settings that range from total synthesis and methodological chemistry, to medical and materials science. While it has been seen in such a breadth of settings, the typical view of the cyclopropane moiety is that its reactivity is derived primarily from the release of ring strain. While this simplified view is a useful shorthand, it ignores the specific nature of cyclopropyl molecular orbitals. This review aims to present the different facets of cyclopropane bonding by examining the main models that have been used to explain the reactivity of the functionality over the years. However, even with advanced theory, being able to precisely predict the reactivity of an exact system is nigh impossible. Specifically chosen, carbonyl-bearing cyclopropyl species act as so-called acceptor cyclopropanes and, if correctly derivatised, donor–acceptor cyclopropanes. By undertaking a case study of the history of carbonyl cyclopropanes in organic synthesis, this review highlights the relationship between the understanding of theory and pattern recognition in developing new synthetic methods and showcases those successful in balancing this critical junction.1 Cyclopropanes2 The Strain Model3 The Forster–Coulsin–Moffit Model4 The Walsh Model5 Acceptor, Donor, and Donor–Acceptor Cyclopropanes6 Reactions of Carbonyl Cyclopropanes
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Fadeev, Alexander A., Alexey O. Chagarovskiy, Anton S. Makarov, Irina I. Levina, Olga A. Ivanova, Maxim G. Uchuskin, and Igor V. Trushkov. "Synthesis of (Het)aryl 2-(2-hydroxyaryl)cyclopropyl Ketones." Molecules 25, no. 23 (December 5, 2020): 5748. http://dx.doi.org/10.3390/molecules25235748.

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A simple general method for the synthesis of 1-acyl-2-(ortho-hydroxyaryl)cyclopropanes, which belong to the donor–acceptor cyclopropane family, has been developed. This method, based on the Corey–Chaykovsky cyclopropanation of 2-hydroxychalcones, allows for the preparation of a large diversity of hydroxy-substituted cyclopropanes, which can serve as promising building blocks for the synthesis of various bioactive compounds.
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Fang, Zeguo, Nawaf Al-Maharik, Peer Kirsch, Matthias Bremer, Alexandra M. Z. Slawin, and David O’Hagan. "Synthesis of organic liquid crystals containing selectively fluorinated cyclopropanes." Beilstein Journal of Organic Chemistry 16 (April 14, 2020): 674–80. http://dx.doi.org/10.3762/bjoc.16.65.

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This paper describes the synthesis of a series of organic liquid crystals (LCs) containing selectively fluorinated cyclopropanes at their termini. The syntheses used difluorocarbene additions to olefin precursors, an approach which proved straightforward such that these liquid crystal candidates could be efficiently prepared. Their physical and thermodynamic properties were evaluated and depending on individual structures, they either displayed positive or negative dielectric anisotropy. The study gives some guidance into effective structure–property relationships for the design of LCs containing selectively fluorinated cyclopropane motifs.
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Ben Hamadi, Naoufel, Ahlem Guesmi, and Wided Nouira. "Asymmetric one-pot synthesis of cyclopropanes." Macedonian Journal of Chemistry and Chemical Engineering 35, no. 1 (April 18, 2016): 45. http://dx.doi.org/10.20450/mjcce.2016.835.

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Cycloaddition of the diazoalkanes to electron-deficient olefins (in situ) affords polysubstituted cyclopropanes in high yields (up to 85%). Deprotection of the ketal protecting group provided water-soluble cyclopropane-bearing carbohydrate in good yields. Antimicrobial activity screening of the synthesized compounds 8 and 9, utilizing a variety of Gram-positive (Staphylococcus aureus and Enterococcus fecalis), Gram-negative bacteria (Escherichia coli and Klebsiella pneumoniae) and yeast (Candida albicans), exhibited that all the prepared analogues acquire promising activities against both Gram-positive and Gram-negative bacteria especially compounds 9b and 9c (antimicrobial active agents against Gram-negative bacteria).
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Finta, Zoltán, Zoltán Hell, Agnieszka Cwik, and László Tőke. "A Simple Synthesis of 1,1,2-tris-(Hydroxymethyl)-Cyclopropane and Its Dihalo Derivatives." Journal of Chemical Research 2002, no. 9 (September 2002): 459–60. http://dx.doi.org/10.3184/030823402103172653.

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The phase transfer catalytic cyclopropanation of the malonic ester of allylic alcohol or its 3,3-dibromo and 3,3-dichloro derivatives yields bicyclic cyclopropane carboxylic acid lactones; reduction of these lactones with LiAlH4 in boiling THF yields the appropriate 1,1,2-tris-(hydroxymethyl)cyclopropanes in satisfactory yield.
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Trudeau, Stéphane, and Pierre Deslongchamps. "Novel synthesis of a highly functionalized cyclopropane derivative." Canadian Journal of Chemistry 81, no. 9 (September 1, 2003): 1003–11. http://dx.doi.org/10.1139/v03-119.

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A model study was carried out to explore the feasibility of synthesizing fused tricyclic ring structures containing a C7—C8 double bond juncture (steroid numbering) by employing an SN2' cyclization of a silyl enol ether to displace an allylic acetate as the key step. Instead of the anticipated product, highly functionalized cyclopropanes were obtained. These novel cyclopropane structures are the result of the concomitant 1,2-migration of a dithiane thioether moiety and the eventual displacement of the acetate group, followed by the cyclization of the silyl enol ether.Key words: tricycles, SN2' cyclization, inductive effect, cyclopropane.
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Budynina, Ekaterina, Konstantin Ivanov, Ivan Sorokin, and Mikhail Melnikov. "Ring Opening of Donor–Acceptor Cyclopropanes with N-Nucleo­philes." Synthesis 49, no. 14 (May 18, 2017): 3035–68. http://dx.doi.org/10.1055/s-0036-1589021.

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Ring opening of donor–acceptor cyclopropanes with various N-nucleophiles provides a simple approach to 1,3-functionalized compounds that are useful building blocks in organic synthesis, especially in assembling various N-heterocycles, including natural products. In this review, ring-opening reactions of donor–acceptor cyclopropanes with amines, amides, hydrazines, N-heterocycles, nitriles, and the azide ion are summarized.1 Introduction2 Ring Opening with Amines3 Ring Opening with Amines Accompanied by Secondary Processes Involving the N-Center3.1 Reactions of Cyclopropane-1,1-diesters with Primary and Secondary Amines3.1.1 Synthesis of γ-Lactams3.1.2 Synthesis of Pyrroloisoxazolidines and -pyrazolidines3.1.3 Synthesis of Piperidines3.1.4 Synthesis of Azetidine and Quinoline Derivatives3.2 Reactions of Ketocyclopropanes with Primary Amines: Synthesis of Pyrrole Derivatives3.3 Reactions of Сyclopropane-1,1-dicarbonitriles with Primary Amines: Synthesis of Pyrrole Derivatives4 Ring Opening with Tertiary Aliphatic Amines5 Ring Opening with Amides6 Ring Opening with Hydrazines7 Ring Opening with N-Heteroaromatic Compounds7.1 Ring Opening with Pyridines7.2 Ring Opening with Indoles7.3 Ring Opening with Di- and Triazoles7.4 Ring Opening with Pyrimidines8 Ring Opening with Nitriles (Ritter Reaction)9 Ring Opening with the Azide Ion10 Summary
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Gopinath, Purushothaman, and Srinivasan Chandrasekaran. "Recent Advances in the Chemistry of Doubly Activated Cyclopropanes: Synthesis and Reactivity." Current Organic Chemistry 23, no. 3 (May 9, 2019): 276–312. http://dx.doi.org/10.2174/1385272823666190213114604.

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Diactivated cyclopropanes containing two geminal electron withdrawing groups, commonly called as ‘Doubly Activated Cyclopropanes’ are useful synthons for the synthesis of many interesting natural products and functionalized molecules. These geminal electron withdrawing groups (EWG’s) facilitate the regioselective ring opening of cyclopropanes by polarizing the C-C bond adjacent to it. This polarization also allows them to undergo 1,3 dipolar cycloaddition reactions when substituted with a suitable electron donor substituent at the adjacent carbon (donor-acceptor cyclopropanes) in the presence of suitable dipolarophiles. In this review, we discuss the recent advances in the chemistry of doubly activated cyclopropanes: their synthesis, reactions and applications in total synthesis.
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Ledingham, Edward, Christopher Merritt, Christopher Sumby, Michelle Taylor, and Ben Greatrex. "Stereoselective Cyclopropanation of (–)-Levoglucosenone Derivatives Using Sulfonium and Sulfoxonium Ylides." Synthesis 49, no. 12 (March 17, 2017): 2652–62. http://dx.doi.org/10.1055/s-0036-1588971.

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The synthesis of tri- and tetrasubstituted cyclopropanes from 3-aryl-substituted levoglucosenones (LGO) has been developed. In contrast to the unstabilised ylide dimethylsulfonium methylide which gives epoxides from LGO via 1,2-addition, we have found that the soft nucleophile dimethylsulfoxonium methylide affords cyclopropanes in moderate yields from LGO and in excellent yields and stereoselectivity with 3-aryl LGO derivatives. The use of 1,1,3,3-tetramethylguanidine as base in DMSO to generate the ylide provided the best yields and shortest reaction times. Ester stabilised sulfonium ylides could also be used to generate tetrasubstituted cyclopropane derivatives. One of the products was converted into a cyclopropyl lactone via Baeyer–Villiger oxidation to demonstrate the utility of applying cyclopropanation chemistry to LGO.
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Song, Xixi, Junbiao Chang, Yuanyuan Zhu, Shuang Zhao, and Minli Zhang. "Diastereoselective Synthesis of Spirobarbiturate-Cyclopropanes through Organobase-Mediated Spirocyclopropanation of Barbiturate-Based Olefins with Benzyl Chlorides." Synthesis 51, no. 04 (November 6, 2018): 899–906. http://dx.doi.org/10.1055/s-0037-1609637.

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The organobase-mediated diastereoselective spirocyclopropanation of barbiturate-based olefins with 2,4-disubstituted benzyl chlorides has been developed. The reactions were carried out efficiently to afford the desired spirobarbiturate-cyclopropanes in up to 95% yield with more than 20:1 dr in favor of anti-isomers. In order to extend synthetic utility of the spiro-products, a Lewis acid induced cyclopropane-ring-expansion isomerization was also demonstrated.
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Dissertations / Theses on the topic "Synthesis of cyclopropanes"

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Ambler, P. W. "Asymmetric synthesis of cyclopropanes." Thesis, University of Oxford, 1988. https://ora.ox.ac.uk/objects/uuid:958e77c2-d15e-4d8f-af84-36dca36e4215.

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This thesis is concerned with the asymmetric synthesis of cyclopropyl derivatives via the use of chiral iron acyl complexes of the type (η5-C5H5)Fe(CO)(PPh3)(COCH=CR'R), Chapter 1 reviews previous routes to optically active cyclopropyl derivatives and reviews the use of the chiral auxiliary (η5-C5H5)Fe(CO)(PPh3) for asymmetric synthesis. Chapter 2 describes the synthesis of the complexes (η5-C5H5)Fe(CO)(PPh3)(COCH=CRR') and presents a conformational analysis of the α, β-unsaturated acyl ligand. Chapter 3 describes the diastereoselective synthesis of cis- substituted cyclopropyl complexes via the reaction of Z-α, β-unsaturated iron acyl complexes with electrophilic alkylidene species. Decomplexation, to give the corresponding cyclopropyl esters, occurred without epimerisation of the cyclopropane ring. By the use of homochiral iron acyl complexes the enantioselective synthesis of cyclopropyl derivatives was achieved. Section A describes methylene addition and Section B isopropylidene addition reactions. Section C describes attempts to synthesise pyrethroid insecticide precursors which occurred with good diastereoselectivity but poor regioselectivity. Section D describes electrophilic ethylidene addition reactions in which the chiral auxiliary exerts good stereochemical control over three new chiral centres. Chapter 4 describes the diastereoselective synthesis of trans- substituted cyclopropyl complexes via the reaction of E-α, β-unsaturated iron acyl complexes with nucleophilic alkylidene transfer reagents. Section A describes methylene transfer reagents. Whilst α-lithiosulphides and α-lithiosulphoxides were of limited use, iodomethyllithium (generated in situ) resulted in highly diastereoselective syntheses of the cyclopropyl complexes. Decomplexation, to give the corresponding cyclopropyl esters, occurred without epimerisation of the cyclopropane ring. By the use of homochiral iron acyl complexes the enantioselective synthesis of cyclopropyl derivatives was achieved. Section B describes the generation of 1-iodoethyllithium and 1-iodobutyllithium and their reactions as nucleophilic alkylidene transfer reagents. The stereo- chemistry at two of the new chiral centres is controlled by the iron chiral auxiliary, whilst that at a third is controlled by a number of factors.
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Watson, Hayley. "Synthesis and reactivity of cyclopropanes and cyclopropenes." Thesis, Loughborough University, 2011. https://dspace.lboro.ac.uk/2134/9032.

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Activated cyclopropanes have been extensively used in synthetic chemistry as precursors for cycloaddition reactions. The rationale behind this is their ability to undergo ring-opening when activated by a Lewis acid, this can be enhanced further by the presence of a carbocation stabilising group like electron-rich aromatics. The stabilised dipole formed after ring opening can be trapped with suitable electrophiles such as imines and aldehydes via a [3+2] cycloaddition reaction. This results in the synthesis of pyrrolidines and tetrahydrofurans in excellent yields but moderate diastereoselectivity. Similarly, 6-membered heterocycles can be formed via a [3+3] cycloaddition reaction of activated cyclopropanes with nitrones. Now to extend the scope of the methodology, a [3+3] dipolar cycloaddition has been developed using activated 2,3 disubstituted cyclopropane diesters to access a range of highly functionalised oxazines in moderate to good yields (50-75%) and with reasonable diastereoselectivity. The use of activated symmetrical disubstituted cyclopropanes afforded the desired oxazines in a regio- and diastereocontrolled manner, while the use of unsymmetrical cyclopropanes significantly reduced the diastereoselectivity of the reaction. The stereochemistry outcome of the reaction developed was determined by nOe analyses and X-ray diffraction structures could be recorded in some examples. A new methodology has also been developed to gain access to novel N-heterocyclic- and phenol- substituted cyclopropanes in one step from the corresponding cyclopropene via a conjugated addition.
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Minicone, Fabrizio. "Stereoselective synthesis of cyclopropanes with quaternary carbon centres." Thesis, Queen Mary, University of London, 2014. http://qmro.qmul.ac.uk/xmlui/handle/123456789/8766.

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Multi-substituted optically pure cyclopropanes are important motifs present in many agrochemicals, pharmaceuticals and materials employed in manifold applications. Their synthesis is challenging due to both the strained conformation and the need to control both the relative and absolute stereochemistry. This thesis describes an investigation of the scope of the Wadsworth-Emmons cyclopropanation, highlighting it as a potential efficient methodology for diastereoselective and enantiospecific synthesis of these valuable ring systems. Chapter 1 is an introduction to the cyclopropanation protocols and is split in two subsections. The first is a description of the currently most exploited synthetic pathways to cyclopropanes, with analysis of their substrate scope and critical analysis of their limitations as compared to potential of the Wadsworth-Emmons cyclopropanation (Sections 1.1 to 1.3). The latter section consists of a review on the history and the evolution of this procedure and introduces the preconditions for the development of the project (Sections 1.4 to 1.17). Chapter 2 describes the results and discussion, introducing the use of novel alkyl-substituted triethyl phosphonoacetates to yield cyclopropyl-esters containing quaternary stereocentres. The high yields and the excellent trans-diastereoselectivity values obtained (proved by X-ray crystallography) allowed the proposal of a suggested reaction mechanism, which is supported by the subsequent experiments carried out in the presence of other functional groups, e.g. other carbonyls, nitriles, hetero-aromatics, substituted phenyl rings. This study was further extended to examine the effect of fluorine atom, due to its importance in biologically active environments. The study on the stereochemistry of the Wadsworth-Emmons cyclopropanation has been strongly supported by a range of X-ray crystal structures of the cyclopropane products. The chapter ends with an empirical set of guidelines, helpful for the design of successful cyclopropanations. Chapter 3, describes the experimental methods in full as well as full characterisation of the products obtained. Literature references, noted throughout the thesis, are listed in the final chapter.
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Sweesi, Miloud E. M. "Studies of the synthesis of cyclopropanes and cyclobutenes." Thesis, Bangor University, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.438828.

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Clarke, C. "Comparative chemistry of protected phosphines within the synthesis of cyclopropanes." Thesis, University of Cambridge, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.597723.

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On treatment with base, diphenylphosphinoyl esters 3 (X=O) give cyclopropanes 4 via a series of steps including intramolecular acyl and phosphinoyl transfer processes. β-Substituted esters have been shown to give cyclopropanes with high diastereoselectivity. This thesis describes the synthesis of optically active β-substituted esters using Evans’ alkylation methodology and their use in the stereocontrolled synthesis of substituted cyclopropanes. It was found that that phosphine oxide 1 (X=O) is unstable in the conditions of the alkylation reaction and the corresponding phosphine borane 1 (X=BH3) was employed with greater success. The thesis also describes investigations into the potential formation of cyclopropanes 4 from esters 3 (X= BH3/S) without prior conversion to the phosphine oxide 3 (X=O). It has been proposed that a phosphine ester is a key intermediate in the formation of cyclopropanes 4 from diphenylphosphinoyl esters 3 (X=O). Detailed in this thesis, is an investigation into the synthesis of optically active cyclopropanes 8 from phosphonate esters 7 prepared by an Evans’ alkylation route. Also included in this thesis are studies into the relative rates of deprotonation and the palladium-catalysed hydrogenation reactions of allyl phosphine oxides, boranes and sulfides. Phosphine oxides have also been used in the synthesis of cyclopropanes via a route analogous to that of the Wadsworth-Emmons cyclopropanation reaction.
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Ner, S. K. "The synthesis and testing of cyclopropane inhibitors of Carboxypeptidase A." Thesis, University of Strathclyde, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381719.

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Huang, Weisheng. "Catalytic asymmetric cyclopropanation and oxidation of tri-, di- and monofluoromethyl styrenes Rhodium catalysed enantioselective synthesis of mono-(halo)-methyl-cyclopropanes Catalytic enantioselective synthesis of highly functionalized difluoromethylated cyclopropanes General catalytic enantioselective access to monohalomethyl and trifluoromethyl cyclopropanes Catalytic asymmetric synthesis of α,α-difluoromethylated and α-fluoromethylated tertiary alcohols." Thesis, Normandie, 2019. http://www.theses.fr/2019NORMIR25.

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Ce manuscrit décrit la synthèse énantiosélective de cyclopropanes trifluorométhylés, difluorométhylés et mono-halométhylés hautement fonctionnalisés. Cette synthèse repose sur la cyclopropanation d’alcènes. De plus, la synthèse d’alcools tertiaires difluorométhylés à partir des oléfines fluorées correspondantes suivant un processus de dihydroxylation asymétrique est décrite. Ce manuscrit se découpe en 3 chapitres. Le premier chapitre décrit la première synthèse catalytique asymétrique de cyclopropanes difluorométhylés en utilisant le Rh₂((S)-BTPCP)₄ comme catalyseur pour la réaction de cyclopropanation d’oléfines α,α-difluoromethylées avec des composés diazoïques di-accepteurs. Un large éventail de cyclopropanes a été obtenu avec de très bon rendements et d’excellentes diastéréosélectivités et énantiosélectivités (>20:1 et jusqu’à 99% ee). Le second chapitre illustre la synthèse de cyclopropanes trifluorométhylés suivant une stratégie similaire. Ces derniers ont été obtenus avec des très bons rendements et d’excellentes diastéréosélectivités et énantiosélectivités (>20:1 et jusqu’à 99% ee). Ces travaux ont également permis une extension aux dérivés mono-halométhylés. Dans un troisième chapitre, l’époxydation asymétrique de styrenes α,α-difluoromethylés a été étudiée. Malheureusement, tous les essais métallo- ou organocatalysés se sont avérés infructueux. Par la suite la réaction de dihydroxylation asymétrique de ces styrenes α,α-difluorométhylés a été développée pour conduire aux alcools tertiaires difluorométhylés énantioenrichis. L’utilisation d’AD-mix-α et AD-mix-β comme catalyseurs a permis d’obtenir les produits désirés avec de très bons rendements et d’excellentes énantiosélectivités. De plus, cette réaction a été étendue aux styrenes α,α-difluorométhylés, α-monofluorométhylés, β-difluoromethylé et β-trifluorométhylé
This thesis presents the enantioselective synthesis of functionalized trifluoromethyl, difluoromethyl and monohalomethyl cyclopropanes based on the cyclopropanation reaction of alkenes bearing various fluorinated groups. In addition, the synthesis of enantioenriched fluorinated tertiary alcohols resulting from the dihydroxylation of fluorinated olefins is discussed. This thesis is divided into three chapters. In the first chapter, we reported the first example of catalytic asymmetric synthesis of difluoromethyl cyclopropanes, which is achieved by using Rh₂((S)-BTPCP)₄ as a catalyst to perform the cyclopropanation reaction of α,α-difluoromethyl olefins with donor-acceptor diazo compounds and di-acceptor diazo compounds. This methodology allows the access to a broad range of cyclopropanes in high yields with excellent diastereo- and enantioselectivities (up to >20:1 and up to 99% ee). In the second chapter, a practical and efficient asymmetric synthesis of trifluoromethyl cyclopropane derivatives was described and a series of functionalized cyclopropanes were obtained in excellent diastereoselectivities with excellent enantioselectivities (up to >20:1 and 99% ee). These investigations also extended to the synthesis of highly enantioselective monohalomethyl cyclopropanes. In the third chapter, the initial propose aimed at exploring the asymmetric epoxidation of α,α-difluoromethyl styrenes. The reaction was performed in the presence of a metal-catalyst or an organic catalyst, unfortunately, none of the result was positive. Therefore, we turned our attention to the asymmetric synthesis of α,α difluoromethylated tertiary alcohols. To this propose, the use of commercially available reagents AD-mix-α and AD-mix-β as the best catalysts, allowed the reaction with α,α-difluoromethyl styrenes to construct the corresponding α,α-difluoromethylated tertiary alcohols in good to high yields with excellent enantioselectivities (up to 99% ee). In addition, this transformation could be applied to a broad range of substrates, including variety of α,α-difluoromethyl styrenes, α-monofluoromethyl styrenes, β-difluoromethyl styrene and β-trifluoromethyl styrene
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Dorsey, Gordon Owen. "Design and synthesis of substituted cyclopropanes as conformationally restrained dipeptide mimics." Thesis, Austin, Texas : University of Texas at Austin, 1992. http://handle.dtic.mil/100.2/ADA252441.

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Thesis (M.A. in Chemistry)--University of Texas at Austin, May 1992.
"May 1992." Description based on title screen as viewed on April 8, 2009. Includes bibliographical references (p. 94-101). Also available in print.
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Ivashkin, Pavel. "Synthesis of original fluorinated cyclopropylcarboxylates." Phd thesis, INSA de Rouen, 2013. http://tel.archives-ouvertes.fr/tel-00924650.

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Organofluorine compounds constitute a large part of all the drugs, crop protection agents and advanced materials produced nowadays. Therefore, there is a great interest in developing the new methods of synthesis of organofluorine compounds. In this thesis we report a novel method of synthesis of monofluorinated cyclopropanes based on the Michael-initiating ring closure (MIRC) reaction. Our method allows obtaining polysubstituted monofluorinated cyclopropanes from ethyl dibromofluoroacetate and various Michael acceptors. We have also implemented the asymetric version of cyclopropanation using a novel oxazolodinone-derived chiral fluorinated reagent. In the final part of this thesis we report the synthesis of a fluorinated analog of L-FAP4, a potent agonist of group II metabotropic glutamate receptors (mGluR II). Incorporation of a fluorine atom is expected to increase the biological activity and bioavailabiblity of this compound.
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Highton, Adrian. "Organic synthesis using iron (III) mediated fragmentation reactions of silyoxycyclopropanes." Thesis, University of Nottingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.311749.

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Books on the topic "Synthesis of cyclopropanes"

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Kulinkovich, Oleg G. Cyclopropanes in organic synthesis. Hoboken, New Jersey: John Wiley & Sons, Inc., 2015.

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Kulinkovich, Oleg G. Cyclopropanes in Organic Synthesis. Hoboken, NJ: John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781118978429.

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1938-, McKervey M. Anthony, and Ye Tao 1963-, eds. Modern catalytic methods for organic synthesis with diazo compounds: From cyclopropanes to ylides. New York: Wiley, 1998.

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Kulinkovich, Oleg G. Cyclopropanes in Organic Synthesis. Wiley & Sons, Incorporated, John, 2015.

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Kulinkovich, Oleg G. Cyclopropanes in Organic Synthesis. Wiley & Sons, Incorporated, John, 2015.

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Shi, Min, Lixiong Shao, and Jianmei Lu. Chemical Transformations of Vinylidenecyclopropanes. Springer, 2012.

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Chemical Transformations Of Vinylidenecyclopropanes. Springer, 2012.

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Book chapters on the topic "Synthesis of cyclopropanes"

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Reißig, H. U. "Donor-Acceptor-Substituted Cyclopropanes via Fischer Carbene Complexes." In Organometallics in Organic Synthesis 2, 311–22. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74269-9_17.

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Gao, Yang, Xu-Fei Fu, and Zhi-Xiang Yu. "Transition Metal-Catalyzed Cycloadditions of Cyclopropanes for the Synthesis of Carbocycles: C–C Activation in Cyclopropanes." In Topics in Current Chemistry, 195–231. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/128_2014_527.

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Kimura, Makoto, Hirotaka Kawai, and Yasuhiko Sawaki. "Ring Opening Reaction of Phenylthio-Cyclopropanes by Anodic or Photochemical One-Electron Oxidation." In Novel Trends in Electroorganic Synthesis, 77–78. Tokyo: Springer Japan, 1998. http://dx.doi.org/10.1007/978-4-431-65924-2_22.

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Reißig, Hans-Ulrich. "Donor-acceptor-substituted cyclopropanes: Versatile building blocks in organic synthesis." In Topics in Current Chemistry, 73–135. Berlin, Heidelberg: Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/bfb0111229.

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Szymoniak, Jan, and Philippe Bertus. "Zirconocene Complexes as New Reagents for the Synthesis of Cyclopropanes." In New Aspects of Zirconium Containing Organic Compounds, 107–32. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/b98422.

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Salaün, Jacques R. Y. "Synthesis and synthetic applications of 1-donor substituted cyclopropanes with ethynyl, vinyl and carbonyl groups." In Topics in Current Chemistry, 1–71. Berlin, Heidelberg: Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/bfb0111228.

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Taguchi, Takeo, Akira Shibuya, and Tsutomu Morikawa. "Asymmetric Synthesis of Functionalized Fluorinated Cyclopropanes and Its Application to Fluoromethano Amino Acids." In ACS Symposium Series, 73–82. Washington, DC: American Chemical Society, 1996. http://dx.doi.org/10.1021/bk-1996-0639.ch005.

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Salaün, Jacques. "Cyclopropane Derivatives and their Diverse Biological Activities." In Small Ring Compounds in Organic Synthesis VI, 1–67. Berlin, Heidelberg: Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/3-540-48255-5_1.

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Mizuno, Kazuhiko, Shogo Nishioka, Hajime Maeda, and Nobuyuki Ichinose. "Formation and Reactivity of Radical Cations of Cyclopropane Derivatives." In Novel Trends in Electroorganic Synthesis, 37–38. Tokyo: Springer Japan, 1998. http://dx.doi.org/10.1007/978-4-431-65924-2_10.

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Srivastava, V. P., C. Mapelli, W. B. Iturrian, E. W. Taylor, and C. H. Stammer. "Synthesis and biological activity of cyclopropane TRH analogs." In Peptides, 219–22. Dordrecht: Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2264-1_74.

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Conference papers on the topic "Synthesis of cyclopropanes"

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Bower, John F. "Directing Group Enhanced Carbonylative Ring Expansions of Amino Substituted Cyclopropanes." In 15th Brazilian Meeting on Organic Synthesis. São Paulo: Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-young4.

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Tabarez, Carlos, Alexander Khrizman, Patrick Moyna, and Guillermo Moyna. "Mechanistic Studies of the Formation of Functionalized Cyclopropanes through Photoisomerization of Tropolone Diels-Alder Adducts." In 14th Brazilian Meeting on Organic Synthesis. São Paulo: Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0074-1.

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Tabarez, Carlos, Alexander Khrizman, Patrick Moyna, and and Guillermo Moyna. "Mechanistic Studies of the Formation of Functionalized Cyclopropanes through Photoisomerization of Tropolone Diels-Alder Adducts." In 14th Brazilian Meeting on Organic Synthesis. São Paulo: Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0085-1.

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Marini, Francesca, Valentina Frullini, Silvia Sternativo, Luana Bagnoli, and Claudio Santi. "Stereoselective synthesis of cyclopropanes from vinyl selenones via a Michael-initiated ring closure reaction." In The 17th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2013. http://dx.doi.org/10.3390/ecsoc-17-a011.

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Wessig, P., and O. Mühling. "A New Photochemical Route to Cyclopropanes and Bicyclo[n,1,0]alkanes." In The 4th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2000. http://dx.doi.org/10.3390/ecsoc-4-01791.

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Hou, Shanshan, Yuanzhang Zhou, Wei Lu, Jiaqian Han, Ziwei Zhang, and Shan Xu. "Synthesis of 3-(4-aminophenyl) cyclopropane-1, 1,2,2-tetracarbonitrile." In 2016 4th International Conference on Mechanical Materials and Manufacturing Engineering. Paris, France: Atlantis Press, 2016. http://dx.doi.org/10.2991/mmme-16.2016.92.

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Marin-Luna, Marta, Belen Martinez-Gualda, Mateo Alajarin, and Angel Vidal. "Exploring cyclopropane-heterocumulene [3 + 2] intramolecular cycloadditions on ortho-benzylydene scaffolds." In The 17th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2013. http://dx.doi.org/10.3390/ecsoc-17-a024.

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Zhou, Zhihui, Yiling Zhang, Jie He, Jianqing Zhang, Qinrong Jiang, and Shan Xu. "Synthesis of N-(4-fluorophenyl)-1-(pyrrolidine-1-carbonyl) cyclopropane-1-carboxamide." In 3RD INTERNATIONAL CONFERENCE ON FRONTIERS OF BIOLOGICAL SCIENCES AND ENGINEERING (FBSE 2020). AIP Publishing, 2021. http://dx.doi.org/10.1063/5.0048414.

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Takahashi, K., and S. Tarutani. "Novel charge-transfer complexes derived from 1,2-bis-benzoquino)-3-(dicyanomenfyleneselenienoquino)cyclopropane derivative and TTF or TTT with metallic behavior." In International Conference on Science and Technology of Synthetic Metals. IEEE, 1994. http://dx.doi.org/10.1109/stsm.1994.835456.

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