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Journal articles on the topic 'Symptoms'

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Author: Grafiati
Published: 4 June 2021
Last updated: 29 July 2024

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1

Rudebeck, Carl Edvard. "Symptoms and symptom presentation." Scandinavian Journal of Primary Health Care 10, sup1 (January 1992): 48–60. http://dx.doi.org/10.3109/02813439209014090.

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2

WOODS, NANCY FUGATE, ELLEN SULLIVAN MITCHELL, and MARTHA LENTZ. "Premenstrual Symptoms: Delineating Symptom Clusters." Journal of Women's Health & Gender-Based Medicine 8, no. 8 (October 1999): 1053–62. http://dx.doi.org/10.1089/jwh.1.1999.8.1053.

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3

Blaivas, Jerry G. "Urinary Symptoms and Symptom Scores." Journal of Urology 150, no. 5 Part 2 (November 1993): 1714. http://dx.doi.org/10.1016/s0022-5347(17)35875-5.

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4

Meier, Marieke, Berta J. Summers, and Ulrike Buhlmann. "Which Symptoms Bridge Symptoms of Depression and Symptoms of Eating Disorders?" Journal of Nervous & Mental Disease 212, no. 1 (January 2024): 61–67. http://dx.doi.org/10.1097/nmd.0000000000001715.

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Abstract Depression is a common comorbid mental illness in eating disorders (EDs). Network theory focuses on interactions between symptoms, but findings from network analyses of EDs and depression need to be replicated to make reliable claims about the nature of symptomatic interplay. We used cross-sectional data of 366 online-recruited participants with clinically elevated ED symptomatology and constructed a regularized partial correlation network with ED and depression symptoms. To determine each symptom's influence, we calculated expected influence (EI) and bridge EI to identify symptoms that bridged symptoms of depression and ED. Concerns that others see one eat, fear of weight gain, and fear of loss of control over eating were especially important among the ED symptoms. Loss of interest and feeling sad were the key depression symptoms. Eating in secret and low self-esteem emerged as potential bridge symptoms between clusters. These findings regarding bridge symptoms partially overlap with prior network analyses in nonclinical and clinical samples. Future studies that investigate symptom interplay via a longitudinal design to deduce causality are needed.
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5

Diorgu, Faith C. "Beside Somatization Symptoms Post-Partum Depression Symptoms are Expressed." Journal of Advanced Research in Psychology & Psychotherapy 02, no. 02 (June 7, 2019): 5–8. http://dx.doi.org/10.24321/2581.5822.201907.

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6

Alsop, Dennis. "Lack of Symptoms May Be Symptom." Science News 146, no. 22 (November 26, 1994): 355. http://dx.doi.org/10.2307/3978628.

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7

Graven, Lucinda J., Melinda K. Higgins, Carolyn M. Reilly, and Sandra B. Dunbar. "Heart Failure Symptoms Profile Associated With Depressive Symptoms." Clinical Nursing Research 29, no. 2 (February 14, 2018): 73–83. http://dx.doi.org/10.1177/1054773818757312.

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Heart failure (HF) symptoms are known to influence depressive symptoms, yet a symptom profile has not been identified. HF symptoms relative to symptom experience (frequency, severity, interference with physical activity and enjoyment of life) associated with depressive symptoms were examined. Data from three HF studies ( N = 308) which used the Heart Failure Symptom Survey were included in this cross-sectional secondary analysis. Supervised classification for and identification of symptoms most associated with depressive symptoms were accomplished using random forest algorithms via conditional inference trees. The HF symptom profile associated with depressive symptoms across all four symptom experience domains included fatigue, dizziness, and forgetfulness/difficulty concentrating. Abdominal bloating, worsening cough, and difficulty sleeping were also important, but did not consistently rank in the top 5 for symptom importance relative to all symptom experience domains. Symptom profiling may enhance early identification of patients at risk for depressive symptoms and inform symptom management interventions.
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8

Cohen, Marlene Z., Lori Williams, Patti Knight, Julie Snider, Kavin Hanzik, and Michael J. Fisch. "Symptom masquerade: understanding the meaning of symptoms." Supportive Care in Cancer 12, no. 3 (March 1, 2004): 184–90. http://dx.doi.org/10.1007/s00520-003-0577-y.

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9

Denes, Magda. "Symptoms, Symptoms, Everywhere." Contemporary Psychology: A Journal of Reviews 37, no. 7 (July 1992): 684. http://dx.doi.org/10.1037/032356.

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10

McKenna, P. J., C. E. Lund, and Ann M. Mortimer. "Negative Symptoms: Relationship to Other Schizophrenic Symptom Classes." British Journal of Psychiatry 155, S7 (November 1989): 104–7. http://dx.doi.org/10.1192/s0007125000291617.

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If negative symptoms represent a distinct class of schizophrenic symptoms, they should, to paraphrase Bleuler (1911), be more closely related to each other than they are to other schizophrenic symptoms. The first part of this statement, that negative symptoms are intrinsically related to each other, has received considerable experimental support (Andreasen, this volume; Mortimer et al, this volume). The second, that negative symptoms are unrelated to other schizophrenic symptoms, has been somewhat more unevenly investigated.
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Semerci, Remziye, Melahat Akgunmela Kostak, Tuba Eren, Filiz Savran, and Gulcan Avci. "Symptoms and symptom clusters in adolescents with cancer." International Journal of Emerging Trends in Health Sciences 5, no. 2 (August 21, 2021): 14–24. http://dx.doi.org/10.18844/ijeths.v5i2.5559.

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Abstract Clinical specialists have suggested that adolescents with cancer experience multiple problems including physical, psychological, and emotional symptoms. This study aimed to identify symptoms and symptoms clusters among adolescent inpatients and outpatients receiving cancer treatment. The study’s sample consisted of 26 adolescents who were selected with the purposeful sampling method in a paediatric oncology unit in Edirne, Turkey. Data were collected using the Memorial Symptom Assessment Scale (MSAS). From the results of the research, in terms of symptoms, outpatients reported a greater lack of concentration than inpatients did. Inpatients reported more hair loss and weight loss symptoms than outpatients. Adolescent inpatients and outpatients experienced the most symptoms during the treatment. Inpatient adolescents experienced more acute treatment-related symptoms than did outpatients. The study recommends regular monitoring and screening for nurses to identify symptom and symptom clusters. Keywords: Adolescent; nursing; symptom cluster; symptom assessment; cancer;
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12

Gil-Gouveia, Raquel, António G. Oliveira, and Isabel Pavão Martins. "The impact of cognitive symptoms on migraine attack-related disability." Cephalalgia 36, no. 5 (September 8, 2015): 422–30. http://dx.doi.org/10.1177/0333102415604471.

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Background The socio-economic impact of migraine is mostly related to work loss either by absenteeism or decreased work performance. Migraine-associated cognitive dysfunction during an attack may contribute to these difficulties. Objective The objective of this article is to analyze the presence and relevance of cognitive symptoms during migraine attacks and to relate their intensity and symptom-related disability with other migraine-defining symptoms. Methods Consecutive migraine patients of a headache clinic completed diaries scoring each migraine symptom (including cognitive symptoms) intensity and symptom-related disability. Results Of 100 consecutive patients included in this study, 34 (all females, age average 31.8 ± 8.8 years) returned information on 229 attacks, on average 6.7 per participant. Every symptom’s intensity was always rated slightly higher than the disability it caused. Pain was the symptom scored with the highest intensity and disability, followed by cognitive symptoms (difficulty in thinking and worsening with mental effort) and photo- and phonophobia. Scoring was independent of any of the clinical variables. Attack intensity and disability scores correlated with intensity and disability from pain and from worsening with mental effort. Conclusions Attack-related cognitive symptoms are intense and disabling. Some attack-related cognitive symptoms correlate to intensity and disability subjectively attributed to the migraine attack. Cognitive performance should be addressed as a valuable secondary endpoint in trials of acute migraine treatment.
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13

Gilbert, Cody Sykes, Mitch Earleywine, Maha N. Mian, and Brianna R. Altman. "Symptom specificity of ayahuasca's effect on depressive symptoms." Journal of Psychedelic Studies 5, no. 1 (May 11, 2021): 37–43. http://dx.doi.org/10.1556/2054.2021.00165.

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AbstractBackgroundAyahuasca's effects on symptoms of depression have generated considerable optimism. Clients frequently report more concern about some symptoms than others, and available treatments alter symptoms differentially. Few studies address the symptom specificity of this psychoactive brew.AimsWe examined self-reported effects of ayahuasca on the individual symptoms of depression assessed by the 10-item short-form of Center for Epidemiological Studies of Depression (CESD-10).MethodsWe asked over 120 participants to complete a retrospective assessment of CESD-10 symptoms one month before and one month after using ayahuasca.ResultsParticipants indicated that ayahuasca had a larger influence on affective symptoms like hope, depressed mood, and happiness, than cognitive, interpersonal, and somatic symptoms like restless sleep, loneliness, and difficulty focusing.ConclusionsPotential clients might appreciate identifying if different treatments provide more relief for some depressive symptoms than others. We examined retrospective reports of ayahuasca's potential for differential impact. Those eager to alter hope, happiness, and other affective symptoms will likely find ayahuasca more helpful than those who want an intervention for restless sleep, loneliness, or trouble focusing. This symptom specificity parallels the effects of serotonergic antidepressant medications, suggesting that psychedelic-assisted psychotherapy using ayahuasca might have considerable appeal for those who seek comparable relief but would rather not use prescription serotonergic medications. Jumpstarting psychotherapy with the rapid onset of ayahuasca-induced relief also appears to have potential.
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14

Baby Thomas, Mebin, and Nazar M. "Correlation of International Prostate Symptom Score with Intravesical Prostatic Protrusion in Men with Lower Urinary Tract Symptoms." International Journal of Science and Research (IJSR) 12, no. 12 (December 5, 2023): 948–51. http://dx.doi.org/10.21275/sr231210080040.

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15

Chaabouni, A., J. Houwen, H. Peters, K. van Boven, H. Schers, and T. Olde Hartman. "Symptom diagnoses in primary care: Which symptoms persist?" Journal of Psychosomatic Research 157 (June 2022): 110836. http://dx.doi.org/10.1016/j.jpsychores.2022.110836.

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16

Kolk, Annemarie M., Gerrit J. F. P. Hanewald, Simon Schagen, and Cecile M. T. Gijsbers van Wijk. "A symptom perception approach to common physical symptoms." Social Science & Medicine 57, no. 12 (December 2003): 2343–54. http://dx.doi.org/10.1016/s0277-9536(02)00451-3.

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17

Ho, Suzanne C., Sieu Gaen Chan, Yin Bing Yip, Anna Cheng, Qilong Yi, and Cynthia Chan. "Menopausal symptoms and symptom clustering in Chinese women." Maturitas 33, no. 3 (December 1999): 219–27. http://dx.doi.org/10.1016/s0378-5122(99)00056-0.

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18

Hsiao, Chao-Pin, Lois J. Loescher, and Ida M. (Ki) Moore. "Symptoms and Symptom Distress in Localized Prostate Cancer." Cancer Nursing 30, no. 6 (November 2007): E19—E32. http://dx.doi.org/10.1097/01.ncc.0000300163.13639.bc.

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19

Grant, Igor, Thomas Patterson, Richard Olshen, and Joel Yager. "Life events do not predict symptoms: Symptoms predict symptoms." Journal of Behavioral Medicine 10, no. 3 (June 1987): 231–40. http://dx.doi.org/10.1007/bf00846537.

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20

Rabin, Carolyn, Sandra Ward, Howard Leventhal, and Mark Schmitz. "Explaining retrospective reports of symptoms in patients undergoing chemotherapy: Anxiety, initial symptom experience, and posttreatment symptoms." Health Psychology 20, no. 2 (2001): 91–98. http://dx.doi.org/10.1037/0278-6133.20.2.91.

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21

Zhao, Yan, Yin Zhang, Sisi Zheng, Meng Fang, Juan Huang, and Ling Zhang. "Manic Residual Symptoms Also Deserve Attention: A Symptom Network Analysis of Residual Symptoms in Bipolar Disorder." Neuropsychiatric Disease and Treatment Volume 20 (July 2024): 1397–408. http://dx.doi.org/10.2147/ndt.s466090.

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22

Portillo, Carmen J., William L. Holzemer, and Fang-Yu Chou. "HIV Symptoms." Annual Review of Nursing Research 25, no. 1 (January 2007): 259–91. http://dx.doi.org/10.1891/0739-6686.25.1.259.

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People with HIV/AIDS are a vulnerable group whose symptoms can seriously affect their quality of life. HIV/AIDS symptoms can result from the disease itself, from secondary complications of the disease, or from side-effects of highly active antiretroviral therapy (HAART) and other medications related to comorbidities. HIV symptoms are the single most important indicators for patients and practitioners. Symptoms prompt patients to seek medical attention and provide health care providers with essential clues about changes in health status and quality of life. Despite increased recognition of the importance of addressing symptoms among people with HIV/AIDS, few studies have examined the management of HIV symptoms. This chapter introduces HIV symptoms, reports on the methods of review, provides an overview of contextual issues including the literature on symptoms, issues related to symptom measures, theoretical foundations on symptom management, HIV-specific measures, non-HIV-specific measures, translation of findings into practice, and implications for future research and policy.
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23

McCall, Maura K., Ansley Grimes Stanfill, Elizabeth Skrovanek, Jessica Renee Pforr, Susan W. Wesmiller, and Yvette P. Conley. "Symptom Science: Omics Supports Common Biological Underpinnings Across Symptoms." Biological Research For Nursing 20, no. 2 (January 11, 2018): 183–91. http://dx.doi.org/10.1177/1099800417751069.

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For precision health care to be successful, an in-depth understanding of the biological mechanisms for symptom development and severity is essential. Omics-based research approaches facilitate identification of the biological underpinnings of symptoms. We reviewed literature for omics-based approaches and exemplar symptoms (sleep disruption, cognitive impairment, fatigue, gastrointestinal [GI] distress, and pain) to identify genes associated with the symptom or symptoms across disease processes. The review yielded 27 genes associated with more than one symptom. ABCB1 (MDR1), APOE, BDNF, CNR1, COMT, DAT1 (SLC6A3), DRD4, ESR1, HLA-DRB1, IL10, IL1B, IL6, LTA, PTGS2 (COX-2), SLC6A4, and TNF were associated with cognitive impairment and pain, which had the most genes in common. COMT and TNF were related to all symptoms except sleep disruption. IL1B was associated with all symptoms except cognitive impairment. IL10, IL1A, IL1B, IL1RN, IL6, and IL8 (CXCL8) were linked with all the exemplar symptoms in various combinations. ABCB1 (MDR1) and SLC6A4 were associated with cognitive impairment, GI distress, and pain. IL10 and IL6 were linked to cognitive impairment, fatigue, and pain. APOE and BDNF were associated with sleep disruption, cognitive impairment, and pain. The 27 genes were associated with canonical pathways including immune, inflammatory, and cell signaling. The pathway analysis generated a 15-gene model from the 27 as well as 3 networks, which incorporated new candidate genes. The findings support the hypothesis of overlapping biological underpinnings across the exemplar symptoms. Candidate genes may be targeted in future omics research to identify mechanisms of co-occurring symptoms for potential precision treatments.
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MR, Anitha, and Vijayanath V. "Tattooed Individuals with Psychotic Symptoms." Indian Journal of Anatomy 8, no. 3 (2019): 151–54. http://dx.doi.org/10.21088/ija.2320.0022.8319.2.

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25

Skelton, J. A., Joan E. Loveland, and Jennifer L. Yeagley. "Recalling symptom episodes affects reports of immediately-experienced symptoms: Inducing symptom suggestibility." Psychology & Health 11, no. 2 (February 1996): 183–201. http://dx.doi.org/10.1080/08870449608400252.

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26

Gerstl, Lucia, Raphael Weinberger, Rüdiger von Kries, Florian Heinen, Andreas Sebastian Schroeder, Michaela Veronika Bonfert, Ingo Borggräfe, et al. "Symptom patterns in childhood arterial ischemic stroke: Analysis of a population-based study in Germany." Klinische Pädiatrie 230, no. 06 (October 10, 2018): 319–25. http://dx.doi.org/10.1055/a-0684-9794.

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Hintergrund Die zeitliche Verzögerung zwischen Symptombeginn und Diagnose ist eine Herausforderung in der Behandlung von Kindern mit arteriell ischämischem Schlaganfall. Frühere Studien zur klinischen Präsentation beschäftigten sich v. a. mit kumulativen Symptomen. Zielsetzung Ziel dieser Studie ist es, mögliche Symptommuster aufzuzeigen. Methoden In einer aktiven Beobachtungsstudie zwischen 01/2015 und 12/2016 (ESPED-Studie) wurden Kinder mit Erstdiagnose eines arteriell ischämischen Schlaganfalls eingeschlossen. Isoliert auftretende Erstsymptome wurden verschiedenen Symptomkombinationen gegenübergestellt. Zudem wurde untersucht, inwieweit ein als „akut“ oder „progredient“ klassifiziertes Auftreten der Symptome Rückschlüsse auf die zugrundeliegende Ätiologie erlaubt. Ergebnisse Es wurden 99 Kinder in die Studie eingeschlossen. Unabhängig vom Alter traten überwiegend fokale Symptome auf (86%). Krampfanfälle als Initialsymptom wurden insbesondere bei Säuglingen beschrieben (67%), wohin-gegen diffuse, unspezifische Symptome vor allem bei Vorschulkindern (38%) und älteren Kindern (59%) auftraten. Isoliert traten fokale Symptome bei 37 Kindern auf, 48 Kinder zeigten zusätzlich unspezifische Symptome, darunter auch 9 Kinder mit Krampfanfällen. Isolierte unspezifische Symptome zeigten sich lediglich bei 7 Kindern, 2 Kinder wurden nur mit Krampfanfällen symptomatisch. Die Akuität des Symptombeginns wurde bei 53/78 als „akut“ und bei “25/78 Fällen als „progredient“ klassifiziert, lieferte jedoch keinen Hinweis auf die zugrundeliegende Ätiologie. Schlussfolgerung Jedes neue fokal neurologische Defizit sollte unabhängig vom Auftreten (isoliert oder kombiniert, akut oder progredient) an einen kindlichen Schlaganfall denken lassen. Background Time delay between onset of clinical symptoms and diagnosis is a challenge in childhood arterial ischemic stroke. Most previous studies reported cumulative symptoms. Objective We attempted to identify typical symptom patterns and assessed their emergence in childhood stroke. Methods Prospective active surveillance in ESPED, a hospital based Pediatric Surveillance Unit for rare diseases in Germany, between January 2015 and December 2016. Case definition: first diagnosis of a radiologically confirmed arterial ischemic stroke. Symptom patterns were identified as occurring in isolation or in combination. We distinguished acute vs. progressive onset. We ascertained risk factors to identify the possible etiology. Results 99 children with childhood arterial ischemic stroke were reported. Focal symptoms were the predominant presenting feature (86%), independent of age. Seizures were more often seen in infants < 1 year (67%), whereas diffuse symptoms were more present in pre-school children (38%) and older children (59%). 37 children had focal features alone and 48 additional non-specific features, including 9 with seizures. Isolated non-specific features accounted for 7 cases, and 2 children had (focal) seizures as the only symptom. In 77% of all cases at least one risk factor was identified. The emergence of symptoms was acute in 53/78 cases and progressive in 25/78 cases. The pattern of emergence was unrelated to the underlying etiology. Conclusions Any new focal neurological deficit in isolation, or associated with seizures or further non-specific symptoms should alert to childhood stroke.
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Merckelbach, Harald, Timo Giesbrecht, Dalena van Heugten-van der Kloet, Joop de Jong, Thomas Meyer, and Kim Rietman. "The overlap between dissociative symptoms and symptom over-reporting." European Journal of Psychiatry 29, no. 3 (September 2015): 165–72. http://dx.doi.org/10.4321/s0213-61632015000300001.

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28

Iqbal, Khalid, Michael Flory, and Hilkka Soininen. "Clinical Symptoms and Symptom Signatures of Alzheimer's Disease Subgroups." Journal of Alzheimer's Disease 37, no. 3 (September 24, 2013): 475–81. http://dx.doi.org/10.3233/jad-130899.

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29

Schnedl, Wolfgang J., Sonja Lackner, Dietmar Enko, Michael Schenk, Sandra J. Holasek, and Harald Mangge. "Evaluation of symptoms and symptom combinations in histamine intolerance." Intestinal Research 17, no. 3 (July 30, 2019): 427–33. http://dx.doi.org/10.5217/ir.2018.00152.

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30

Bogaerts, Katleen, Lien Van Eylen, Wan Li, Johan Bresseleers, Ilse Van Diest, Steven De Peuter, Linda Stans, Marc Decramer, and Omer Van den Bergh. "Distorted symptom perception in patients with medically unexplained symptoms." Journal of Abnormal Psychology 119, no. 1 (2010): 226–34. http://dx.doi.org/10.1037/a0017780.

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31

Gosain, Rahul, and Kenneth Miller. "Symptoms and Symptom Management in Long-term Cancer Survivors." Cancer Journal 19, no. 5 (2013): 405–9. http://dx.doi.org/10.1097/01.ppo.0000434391.11187.c3.

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32

Sarode, Sachin C., Nilesh Kumar Sharma, Gargi Sachin Sarode, Sachin Atre, and Shankargouda Patil. "Presenting symptoms and cancer stage: Do symptom locations matter?" Medical Hypotheses 138 (May 2020): 109616. http://dx.doi.org/10.1016/j.mehy.2020.109616.

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33

Thorner, Daniel A., and Jeffrey P. Weiss. "Benign Prostatic Hyperplasia: Symptoms, Symptom Scores, and Outcome Measures." Urologic Clinics of North America 36, no. 4 (November 2009): 417–29. http://dx.doi.org/10.1016/j.ucl.2009.07.001.

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34

Meehan, William P., Michael J. O’Brien, Ellen Geminiani, and Rebekah Mannix. "Initial symptom burden predicts duration of symptoms after concussion." Journal of Science and Medicine in Sport 19, no. 9 (September 2016): 722–25. http://dx.doi.org/10.1016/j.jsams.2015.12.002.

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35

Printza, Athanasia, Athanassios Kyrgidis, Eirini Oikonomidou, and Stefanos Triaridis. "Assessing Laryngopharyngeal Reflux Symptoms with the Reflux Symptom Index." Otolaryngology–Head and Neck Surgery 145, no. 6 (October 10, 2011): 974–80. http://dx.doi.org/10.1177/0194599811425142.

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Objective. To validate the Reflux Symptom Index (RSI) in Greek patients and estimate the prevalence of laryngopharyngeal reflux (LPR) symptoms in the Greek population. Study Design. Prospective, controlled validation study. Setting. Tertiary referral hospital and primary care. Subjects and Methods. For validation purposes, the instrument was administered to 53 patients with confirmed LPR. Sex- and age-matched controls with no LPR or gastroesophageal reflux disease (GERD) symptoms presenting in a primary care setting composed the control group. Reliability and construct validity were statistically appraised. Using the RSI, the authors estimated the prevalence of LPR in a randomly selected sample of the Greek adult population. Results. The mean (SD) RSI score of the 172 sex- and age-matched controls was 3.2 (3.5). The mean (SD) RSI score of the 53 confirmed LPR patients was 19.9 (6.8). Cronbach α was 0.865. Factor analysis verified that the RSI instrument consists of 2 principal factors. To estimate the prevalence of LPR, a representative sample of the Greek adult population (188 subjects) completed the RSI questionnaire: 36.3% were male, and 29.6% were smokers. Mean (SD) age was 53.4 (17.7) years. The instrument was able to discriminate 16 patients with LPR symptoms with a mean (SD) score of 18.91 (6.39). Conclusion. The authors evaluated the internal consistency, reliability, and construct validity of the RSI for the Greek population. Factor analysis of the Greek translation of the RSI demonstrated that it can be a reliable tool in the diagnostic approach of LPR patients. Using the RSI, the authors recorded that the prevalence of LPR in a representative sample of the Greek population is 8.5%.
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Kaiser, S. "Assessment of negative symptoms beyond schizophrenia." European Psychiatry 33, S1 (March 2016): S69—S70. http://dx.doi.org/10.1016/j.eurpsy.2016.01.979.

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IntroductionNegative symptoms have long been recognized as a hallmark of schizophrenia. Newer evidence suggests that negative symptoms can be observed in persons with other disorders or even in non-clinical populations. However, most negative symptom scales are designed to identify clinically relevant symptoms, which might lead to underappreciation of subclinical symptom expression.ObjectivesThe aim of the present study was to establish distributional properties of well-established negative symptom scales in comparison with the newly developed Zurich Negative Symptom Scale, which employs a fully dimensional and continuous approach.MethodsWe included participants with established schizophrenia (n = 65), first-episode psychosis (n = 25), schizotypal personality traits (n = 29) and remitted bipolar disorder (n = 20). Assessment of negative symptoms was conducted with the Zurich Negative Symptom Scale and compared to establish rating scales.ResultsIn this broad sample, measurement of negative symptoms with established negative symptom scales lead to a highly skewed distribution. In other words, established negative symptom scales were able to identify negative symptoms in some participants in the non-schizophrenia spectrum, but a differentiation of negative symptom severity in the subclinical range was not possible. In contrast, the distribution of negative symptoms measured with the Zurich Negative Symptom scale approached normality.ConclusionsNegative symptoms can be observed outside the schizophrenia diagnosis. However, in order to fully explore the continuity of negative symptoms, measurement instruments need to be designed to cover the full range of symptomatology starting at a subclinical level. We propose the newly developed Zurich Negative Symptom Scale as a useful tool in this respect.Disclosure of interestThe author has not supplied his declaration of competing interest.
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Anholt, G., D. Cath, P. van Oppen, M. Eikelenboom, J. Smit, H. van Megen, and A. van Balkom. "Do ADHD and Autism Symptoms Predict Specific OC Symptom Dimensions from OC Symptom Severity in OCD?" European Psychiatry 24, S1 (January 2009): 1. http://dx.doi.org/10.1016/s0924-9338(09)71262-3.

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Backgrond:Autism spectrum disorder (ASD) symptoms and attention deficit/ hyperactivity disorder (ADHD) symptoms are frequently comorbid with obsessive-compulsive disorder (OCD). However, limited research exists with respect to the relations between these symptoms, and their impact on OC symptom severity.Method:109 outpatients with primary OCD and 87 healthy controls were administered OCD, ADHD, and ASD questionnaires. Univariate analyses, correlations, and stepwise regression analyses were conducted.Results:OCD, ADHD, and autism symptoms were highly correlated, with OCD patients showing elevated ADHD as well as autism scores when compared with healthy controls. OCD patients with comorbid ADHD presented with higher autism symptoms and OCD symptoms, yet similar OCD severity scores as OCD without ADHD patients. the attention switching and lack of social skills subscales of the Autism Questionnaire (AQ) were particularly correlated with ADHD and OCD symptoms in the patient group. the AQ subscale attention switching proved to be the most significant predictor of OCD severity and symptoms (with the exception of hoarding). Contrary to expectations, the AQ subscale attention to detail did not predict OCD symptoms, nor did any of the AQ subscale scores predict hoarding symptoms.Conclusions:OCD patients present with elevated scores of ADHD and ASD symptoms, and these symptoms (particularly attention switching) are important in predicting OC symptoms and severity. It is suggested that problems in attention may be related to the uncertainty about one's own memory as demonstrated by OCDs patients, as well as a common factor underlying comorbid ADHD and ASD symptoms.
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Schlechter, Pascal, Tamsin Ford, and Sharon A. S. Neufeld. "Depressive symptom networks in the UK general adolescent population and in those looked after by local authorities." BMJ Mental Health 26, no. 1 (August 2023): e300707. http://dx.doi.org/10.1136/bmjment-2023-300707.

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BackgroundDespite the importance of understanding depressive symptom constellations during adolescence and specifically in looked-after children, studies often only apply sum score models to understand depression in these populations, neglecting associations among single symptoms that can be elucidated in network analysis. The few network analyses in adolescents have relied on different measures to assess depressive symptoms, contributing to inconsistent cross-study results.ObjectiveIn three population-based studies using the Short Mood and Feelings Questionnaire, we used network analyses to study depressive symptoms during adolescence and specifically in looked-after children.MethodWe computed cross-sectional networks (Gaussian Graphical Model) in three separate datasets: the Mental Health of Children and Young People in Great Britain 1999 survey (n=4235, age 10–15 years), the mental health of young people looked after by local authorities in Great Britain 2002 survey (n=643, age 11–17 years) and the Millennium Cohort Study in the UK 2015 (n=11 176, age 14 years).FindingsIn all three networks,self-hateemerged as a key symptom, which aligns with former network studies.I was no good anymorewas also among the most central symptoms. Among looked-after children,I was a bad personconstituted a central symptom, while this was among the least central symptom in the other two datasets. The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition symptomI did not enjoy anythingwas not central.ConclusionsFindings indicate that looked-after children’s depressive symptoms may be more affected by negative self-evaluation compared with the general population.Clinical implicationsIntervention efforts may benefit from being tailored to negative self-evaluations.
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39

Thomas, Shirley, Declan Walsh, and Aynur Aktas. "Are validated symptom assessment instruments comprehensive? “Orphan” and “champion” symptoms." Journal of Clinical Oncology 31, no. 15_suppl (May 20, 2013): e20597-e20597. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e20597.

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e20597 Background: Cancer patients experience multiple symptoms which vary in prevalence, severity, distress and negative impact on life. Comprehensive assessment is essential. Many validated assessment tools are used. They have limitations; varied content, clinical utility, completion rates, and acceptability. The objectives of this study were: Compare common cancer multisymptom assessment instruments to a comprehensive checklist. Identify commonly assessed (“champions”) and frequently neglected (“orphans”) symptoms. Examine the clinical importance of “orphan” symptoms. Methods: A 46-symptom checklist was developed from available evidence. This was compared against the content of 6 commonly used, validated, multisymptom instruments. Those with ≤ 2 symptoms, cancer site-specific, and tumor response instruments were excluded. Results: Symptom numbers varied in the 6 instruments; median (range) 19 (3-32). Of the 46 checklist symptoms, only 28 were present in 1 or more of the instruments. “Orphans”: 18 of the 46 were not evaluated in any of the 6 (e.g., confusion, agitation, early satiety, indigestion, tremors). 12 of the 18 had prevalence rates >10%. These symptoms are also often rated moderate/severe and distressful. “Champions”: Only four checklist symptoms (pain, fatigue, dyspnea, anorexia) were present in all 6 instruments. Conclusions: Eighteen “orphan” symptoms (severe/distressing) were not captured by any tool. Only four “champion” symptoms were present in all validated tools. Unreported and misdiagnosed symptoms can bias our view of the cancer symptom experience. Validated cancer symptom assessment tools do not capture accurate, reliable comprehensive data on the cancer symptom experience. These challenge the validity and reliability of current symptom assessment tools in clinical research.
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Llamas-Ramos, Inés, Jorge Juan Alvarado-Omenat, María Rodrigo-Reguilón, and Rocío Llamas-Ramos. "Quality of Life and Side Effects Management in Cancer Treatment—A Cross Sectional Study." International Journal of Environmental Research and Public Health 20, no. 3 (January 17, 2023): 1708. http://dx.doi.org/10.3390/ijerph20031708.

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Cancer disease is a world problem which is increasing in its prevalence. Oncology patients have a multitude of symptoms derived from the treatments and from the disease itself that affect their quality of life to a greater or lesser extent. The aim of this study has been to discover the physical and psychological symptoms related to chemotherapy treatment in Spanish cancer patients in order to improve their quality of life. Symptoms from the previous week were taken into account and the Memorial Symptom Assessment Scale was used to measure the frequency, severity and associated distress of 32 symptoms. A total of 246 chemotherapy patients at the University Day Hospital in Salamanca completed the scale once while receiving chemotherapy treatment. A 95% confidence interval was considered. The most prevalent symptoms were a lack of energy (76.4%), anxiety (66.7%) and a dry mouth (60.6%). Lung cancer was the most prevalent cancer in men (26%) and breast cancer was the most prevalent cancer in women (72%). There is no consensus on which is the most prevalent symptom in this population and more studies will need to be carried out to determine the best treatment protocols. Symptom’s prevalence knowledge could improve the patients’ care to prevent or avoid complications and to improve the cancer patients’ quality of life.
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Hamizan, A. W., Y. Y. Choo, P. V. Loh, N. F. Abd Talib, M. F. Mohd Ramli, F. D. Zahedi, and S. Husain. "The association between the reflux symptoms index and nasal symptoms among patients with non-allergic rhinitis." Journal of Laryngology & Otology 135, no. 2 (January 26, 2021): 142–46. http://dx.doi.org/10.1017/s0022215120002492.

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AbstractBackgroundLaryngopharyngeal reflux symptoms assessed with the reflux symptom index can overlap with non-allergic rhinitis symptoms. This study aims to explore the association between the reflux symptom index and nasal symptoms in non-allergic rhinitis patients.MethodsA cross-sectional study was conducted on consecutive adults with non-allergic rhinitis. The reflux symptom index (score of more than 13 = laryngopharyngeal reflux) and nasal symptoms (categorised as mild (total score of 0–3), moderate (4–7) or severe (8–12)) were assessed.ResultsThe study included 227 participants (aged 58.64 ± 12.39 years, 59.5 per cent female). The reflux symptom index scores increased with total nasal symptom scores (mild vs moderate vs severe, 8.61 ± 6.27 vs 12.94 ± 7.4 vs 16.40 ± 8.10; p < 0.01). Logistic regression indicated that laryngopharyngeal reflux is more likely in patients with severe nose block (odds ratio 5.47 (95 per cent confidence interval = 2.16–13.87); p < 0.01).ConclusionLaryngopharyngeal reflux symptoms are associated with nasal symptom severity, and nasal symptoms should be primarily treated. Those with predominant nose block and laryngopharyngeal reflux symptoms are more likely to have laryngopharyngeal reflux.
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42

Ladder, Bruce. "Symptoms." Einstein Journal of Biology and Medicine 29, no. 1 (March 2, 2016): 72. http://dx.doi.org/10.23861/ejbm20132970.

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43

Greenberg, Michael I. "Symptoms." Emergency Medicine News 23, no. 3 (April 2001): 44. http://dx.doi.org/10.1097/00132981-200104000-00023.

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Greenberg, Michael I. "Symptoms." Emergency Medicine News 23, no. 6 (June 2001): 27. http://dx.doi.org/10.1097/00132981-200106000-00022.

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Harrigan, Richard, William Brady, and Theodore Chan. "Symptoms." Emergency Medicine News 23, no. 6 (June 2001): 30. http://dx.doi.org/10.1097/00132981-200106000-00026.

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Greenberg, Michael I. "Symptoms." Emergency Medicine News 23, no. 7 (July 2001): 36. http://dx.doi.org/10.1097/00132981-200107000-00020.

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Greenberg, Michael I. "Symptoms." Emergency Medicine News 19, no. 1 (January 2002): 26. http://dx.doi.org/10.1097/00132981-200201000-00021.

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Greenberg, Michael I. "Symptoms." Emergency Medicine News 24, no. 5 (May 2002): 16–18. http://dx.doi.org/10.1097/00132981-200205000-00012.

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Greenberg, Michael I. "Symptoms." Emergency Medicine News 24, no. 5 (May 2002): 16–18. http://dx.doi.org/10.1097/00132981-200205000-00013.

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Greenberg, Michael I. "Symptoms." Emergency Medicine News 25, no. 1 (January 2003): 14. http://dx.doi.org/10.1097/00132981-200301000-00009.

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