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Relevant bibliographies by topics / Swertia chirayita

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Academic literature on the topic 'Swertia chirayita'

Author: Grafiati

Published: 18 May 2024

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Journal articles on the topic "Swertia chirayita"

1

Singh, Nilay, Neetu Sharma, Promila Sharma, Bhawana ., and Bindu Agarwal. "Review of critically endangered medicinal plant Swertia chirayita for developing conservation strategies." Journal of medical pharmaceutical and allied sciences 11, no. 2 (March 30, 2022): 4552–59. http://dx.doi.org/10.55522/jmpas.v11i2.2074.

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AMedicinal plants always play an important role in pharmaceutical applications. Swertia chirayita is one of the chief plants of the Gentianeace family. It is a potent drug used in Ayurveda, Siddha, and Homoeopathy in many formulations and is efficient in the healing of a range of diseases. The foremost emphasis of this assessment is in the direction of evaluating the versatile, multi-potential medicinal use of Swertia chirayita and updating information about pharmacognostical, phytochemical, and pharmacological studies. Swertia chirayitais has extensive types of characteristics, such as antibacterial activity, antifungal activity, antioxidant activity, etc. The current scenario and condition of this plant show that the prevailing number of these species is ebbing at a very great proportion. So, there must be different efficient conservation and sustentation strategies that can be put into effect for the preservation of this plant in its natural ecosystem. If felicitous methods are not augmented and employed, the extinction of these species cannot be ruled out anytime soon in the future. So, at this critical stage, there must be some urgent and active conservation strategies to be implemented at the earliest possible date. Keywords: Swertia chirayita, Gentianaceae, Chemical composition, Amarogentine, Pharmacological.

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Khanal, Supreet, N. Shakya, N. Nepal, and D. Pant. "Swertia chirayita: The Himalayan Herb." International Journal of Applied Sciences and Biotechnology 2, no. 4 (December 25, 2014): 389–92. http://dx.doi.org/10.3126/ijasbt.v2i4.11281.

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Swertia chirayita is a native Himalayan herb typically found in the altitude of 1500 to 3100m. Swertia species are commonly used as primary medicines in fever, digestive and enteric diseases; especially S. chirayita is of principal importance. The pharmacological and ethno-medicinal perspective of the plant is well understood traditionally and pharmaceutically. Its secondary metabolites including glycosides and xanthones show promising bioactivity making it a powerful herb. Mixing of Swertia chirayita with its other species is done routinely in chiretta trade. Extensive wild collection and lack of sustainable conservation has led to the vulnerable status of the wild cultivar. DOI: http://dx.doi.org/10.3126/ijasbt.v2i4.11281 Int J Appl Sci Biotechnol, Vol. 2(4): 389-392

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3

Qura-Tul-Ain, Sidra Mushtaq, Naveeda Manzoor, Mahreen Akhtar, Anila Errum, and Naseem Saud Ahmad. "Comparison of Xanthine Oxidase Inhibitory Effect of Swertia chirayita and Febuxostat in Vitro." Proceedings 35, no. 2 (April 21, 2021): 18–22. http://dx.doi.org/10.47489/pszmc784-35-2-18-22.

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Introduction:Plasma uric acid ? 6.5 to 7.0 mg/dl increases the incidence of gout, hypertension, diabetes mellitus type 2, stroke and heart failure. Low purine diet, use of xanthine oxidase inhibitors allopurinol and febuxostat; or uricosuric agent’s probenecid, sulfinpyrazone and Benzbromarone are being used for treatment. Swertia chirayita extract (SCE) being practiced as anti-inflammatory and anti-oxidant was evaluated for inhibition of xanthine oxidase. Aims & Objectives: To observe the in vitro effect of Swertia chirayita ethanolic extract on xanthine oxidase inhibition and its comparison with medicine febuxostat. Place and duration of study: The study was conducted in Pharmacology Department, University of Health Sciences Lahore during June-August 2017. Material & Methods: Xanthine oxidase (XO) inhibition by ethanolic extract of the herb was compared with febuxostat. Serial dilutions of test compounds ranging from 1.25µg/ml to 100 µg/ml were prepared in absolute ethanol. Fixed volumes of xanthine, xanthine oxidase, phosphate buffer and test compounds were incubated. Uric acid concentration in the reaction mixture was calculated by measuring absorbance at 295nm by using Ultraviolet- Visible Spectrophotometer. Mean values and percent inhibition (± SD) was calculated. EZ Fit Enzyme Kinetic program was also used to calculate inhibitory concentration 50 percent (IC50), Michaelis constant (Km) and maximum rate of reaction (Vmax). Results: At maximum dose, (100 µg/ml) xanthine oxidase inhibition by febuxostat and Swertia chirayita was 98% and 80% percent respectively (p=0.01). Swertia chirayita extract showed IC50 at 9.15± 1.2 µg/ml whereas IC50 of febuxostat was 7.91± 0.9 µg/ml. Conclusion: In the light of XO inhibition, Swertia chirayita has potential to be explored as antihyperuricemic agent.

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Asthana, Rakesh K., Narendra K. Sharma, Dinesh K. Kulshreshtha, and Sunil K. Chatterjee. "A xanthone from Swertia chirayita." Phytochemistry 30, no. 3 (January 1991): 1037–39. http://dx.doi.org/10.1016/0031-9422(91)85308-m.

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Thapa, Rabindra, and Sanjay Kumar Jha. "Study of fungal diseases on Swertia chirayita from cultivated fields of Dolakha district, central Nepal." Our Nature 20, no. 1 (June 6, 2022): 41–47. http://dx.doi.org/10.3126/on.v20i1.44951.

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Swertia chirayita is a medicinally and economically important herb of the family Gentinaceae. It is one of the highly traded, traditionally important medicinal plants. Fungal Pathogens corrupt the quality and amount of Swertia chirayita development, and production and cause terrible well-being of plants as well as monetary problem to the traders. This study was carried out to identify some diseases associated with S. chirayita cultivated fields in Bigu, Khartal, and Boch regions of Dolakha district. The samples were collected from selected sites and cultured on Potato Dextrose Agar media for fungal pathogens. During the investigation, five species of fungal pathogens were identified. Alternaria alternata, Colletotrichum gleosporioides and Curvularia sp. were isolated from leaf. They caused Alternaria leaf spot, Colletotrichum leaf blight, and Curvularia leaf spot. Similarly, stem possesses canker disease and root had root canker, Fusarium oxysporum causing Fusarium wilt, Rhizoctonia sp. causing Rhizoctonia root rot. The presence of illnesses in S. chirayita shows the need for proper plant care.

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Qura-Tul-Ain, Naseem Saud Ahmad, Sidra Mushtaq, Navida Manzoor, Akfish Zaheer, and Faiza Khan. "Anti-hyperuricemic Evaluation of Swertia-chirayita and Febuxostat on Potassium Oxonate Induced Hyperuricemic Animal Model." Proceedings 38, no. 2 (April 29, 2024): 144–49. http://dx.doi.org/10.47489/szmc.v38i2.509.

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Introduction: Hyperuricemia is a metabolic disease characterized by an increase in serum uric acid levels. Hyperuricemia can be controlled by low purine diet or drugs like allopurinol and febuxostat; however, the incidence of adverse effects to these drugs, especially on chronic use, is a major clinical problem. Swertia chirayita; a herb from Gentianaceace family, was selected to observe it’s in vivo uric acid lowering effect in white Albino Wistar rats in whom hyperuricemia was induced through potassium oxonate. Febuxostat was used as a standard. Aims and Objectives: To observe the in vivo effect of different doses of Swertia chirayita extract (SCE) on uric acid levels and to compare its effect with the allopathic medicine febuxostat. Place and Duration of study: A randomized controlled study was held at University of Health Sciences Lahore between June- August 2017. Material and Methods: Forty-eight healthy adult Albino Wistar rats were randomly divided into six groups. Group I and II served as negative and positive controls respectively. Hyperuricemia was induced by injecting KO solution (01ml) intraperitoneally on 1st, 3rd and 7th day of study. Group III received febuxostat 5 mg/kg through oral gavage. Group IV, V and VI were experimental groups, treated with 100, 200 and 400 mg/kg doses of Swertia Chirayita extract respectively through oral route, 02 hours after induction by KO once daily for 07 days. Blood samples were collected to record serum uric acid levels on day zero, first, third and seventh days. (SPSS)version 20 was used for data entry and analysis, pvalue ? 0.05 was given statistical importance. Results: In all experimental groups (IV, V, VI), serum uric acid levels were significantly reduced by Swertia chirayita extract (SCE) (p ? 0.001) as compared to hyperuricemic rats (group II). SCE showed dose dependent SUA suppression. Results of both febuxostat and SCE showed that average SUA levels of these groups were markedly less than hyperuricemic rats (Group II) (p < 0.001) Conclusion: In the light of its hypouricemic activity; we conclude that in the future, Swertia chirayita has the potential for newer therapeutic applications in this regard.

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VERMA, PRAWAL PS, NASHRA AFTAB, VAGMI SINGH, KARUNA SHANKER, and BIRENDRA KUMAR. "Survival, performance and adaptation of Swertia chirayita genotypes at western Himalayan zone of Uttarakhand." Journal of Medicinal and Aromatic Plant Sciences 42, no. 3 (December 31, 2020): 220–28. http://dx.doi.org/10.62029/jmaps.v42i3.verma.

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An experiment was conducted on 5 Swertia chirayita genotypes: Devvan (G1), Yuksom (G2), Sukhia (3), Kaddukhal (G4) and Kalimpong (G5) at three locations in Uttarakhand: Purara, Gwaldam and Kausani of the lower Himalayan range to study the survival, performance and adaptation during October 2018 to January, 2020. Among the studied locations, Gwaldam, Chamoli (Uttarakhand) was found to be the best for growth and performance of all the genotypes, followed by Kausani and Purara. The genotype G5 (Kalimpong) showed a higher survival rate, performance and adaptability compared to others and can be successfully grown to obtain dry herb in Gwaladam. These results suggest that farmers can practice the cultivation of Swertia chirayita at lower altitude areas of the Himalayan zone.

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Phoboo, Susanna, Dipayan Sarkar, Prasanta C. Bhowmik, Pramod Kumar Jha, and Kalidas Shetty. "Improving salinity resilience in Swertia chirayita clonal line with Lactobacillus plantarum." Canadian Journal of Plant Science 96, no. 1 (February 1, 2016): 117–27. http://dx.doi.org/10.1139/cjps-2015-0178.

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Plants defense responses to abiotic stresses, including salinity stress, involve stimulation of defense related pathways such as biosynthesis of secondary metabolites and induction of endogenous antioxidant enzyme responses. In the present study, a single seed origin clonal line of Swertia chirayita inoculated with Lactobacillus plantarum (LP) was grown under different salinity levels. Control had no LP inoculation. S. chirayita inoculated with LP showed higher accumulation of proline, low proline dehydrogenase activity, up-regulation of pentose phosphate pathway, down-regulation of succinate dehydrogenase activity (Krebs cycle) and low total phenolic content with increased salt concentrations. In comparison, S. chirayita without LP adopted a different biochemical mechanism to counter salt stress (NaCl) by up-regulating both pentose phosphate pathway and Krebs cycle along with stimulation of phenolic biosynthesis. Guaiacol peroxidase (GPX) activity increased with and without LP treatment in response to increasing concentrations of salt. These results indicate that S. chirayita inoculated with LP exhibits a greater salinity stress tolerance than S. chirayita without LP by adopting a more energy efficient defense responses and potentially efficiently partitioning carbon flux between primary and secondary metabolism to counter salt induced oxidative stress.

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9

Rijal, Dilli Prasad. "Taxonomic study of some medicinally important species of Swertia L. (Gentianaceae) in Nepal." Botanica Orientalis: Journal of Plant Science 6 (March 15, 2010): 18–24. http://dx.doi.org/10.3126/botor.v6i0.2906.

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Among 100 species of Swertia reported from the world, Nepal harbors 30 species along with four varieties. In Nepal, species of Swertia are highly exploited as raw materials for different traditional medicines. Among them, S. chirayita, a vulnerable species, has been considered to be superior in medicine and trade. One of the main issues in its trade is adulteration with other species which are considered to be inferior in medicinal quality. Species which are mixed with S. chirayita are S. angustifolia, S. ciliata, S. dilatata, S. paniculata, S. racemosa, etc. There is a need for the selection of most important morphological characteristics for instant identification of different species of Swertia to check illegal trade as well as adulteration. This paper aims to provide the most important identifying characters of eight species of Swertia traded from Nepal on the basis of their morphological studies. Color of the petal, number of floral parts (tetramerous vs. pentamerous) and number of glands in petal are the key characters for the identification of the species. Key-words: adulteration; medicinal plant; morphological characters.DOI: 10.3126/botor.v6i0.2906 Botanica Orientalis - Journal of Plant Science (2009) 6: 18-24

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10

Raza, Ayesha, Tayyab Ali, Muhammad Naeem, Muhammad Asim, Fatma Hussain, Zhiye Li, and Abdul Nasir. "Biochemical characterization of bioinspired nanosuspensions from Swertia chirayita extract and their therapeutic effects through nanotechnology approach." PLOS ONE 19, no. 2 (February 8, 2024): e0293116. http://dx.doi.org/10.1371/journal.pone.0293116.

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Swertia chirayita is used as a traditional medicinal plant due to its pharmacological activities, including antioxidant, antidiabetic, antimicrobial, and cytotoxic. This study was aimed to evaluate the therapeutic efficacy of newly synthesized nanosuspensions from Swertia chirayita through nanotechnology for enhanced bioactivities. Biochemical characterization was carried out through spectroscopic analyses of HPLC and FTIR. Results revealed that extract contained higher TPCs (569.6 ± 7.8 mg GAE/100 g)) and TFCs (368.5 ± 9.39 mg CE/100 g) than S. chirayita nanosuspension, TPCs (500.6 ± 7.8 500.6 ± 7.8 mg GAE/100 g) and TFCs (229.5± 3.85 mg CE/100 g). Antioxidant activity was evaluated through DPPH scavenging assay, and nanosuspension exhibited a lower DPPH free radical scavenging potential (06 ±3.61) than extract (28.9± 3.85). Anti-dabetic potential was assessed throughα-amylase inhibition and anti-glycation assays. Extract showed higher (41.4%) antiglycation potential than 35.85% nanosuspension and 19.5% α-amylase inhibitory potential than 5% nanosuspension. Biofilm inhibition activity against E. coli was higher in nanosuspension (69.12%) than extract (62.08%). The extract showed high cytotoxicity potential (51.86%) than nanosuspension (33.63%). These nanosuspensions possessed enhanced bioactivities for therapeutic applications could be explored further for the development of new drugs.

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Dissertations / Theses on the topic "Swertia chirayita"

1

Pradhan, Sabina. "Studies on physiology and bio chemistry of swertia chirayita (Roxb) karsten in Darjeeling hills: influence of plant growth - substances on growth, metabolism and - yield." Thesis, University of North Bengal, 2015. http://ir.nbu.ac.in/hdl.handle.net/123456789/1846.

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Pradhan, Bharat Kumar. "Population studies and habitat characteristics of swertia chirayita (Roxb. ex Fleming) H. Karst. , a threatened Medicinal Herb in Sikkim Himalaya, and Its Conservation." Thesis, University of North Bengal, 2011. http://hdl.handle.net/123456789/1434.

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Book chapters on the topic "Swertia chirayita"

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Dev, Sukh. "Swertia chirayita." In Prime Ayurvedic Plant Drugs, 652–60. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-22075-3_93.

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Mazumder, Md Anisur Rahman, Md Fahad Jubayer, Mohammad Javed Ansari, and Thottiam Vasudevan Ranganathan. "Swertia chirayita (Roxb. ex Flem.): Chirayata/Chiretta." In Immunity Boosting Medicinal Plants of the Western Himalayas, 511–39. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-9501-9_21.

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Khare, C. P. "Swertia chirayita (Roxb. ex Flem.) Karst." In Indian Medicinal Plants, 1. New York, NY: Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-70638-2_1572.

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Akbar, Shahid. "Swertia chirata Buck.-Ham. ex Wall. Swertia chirayita (Roxb.) H. Karsten (Gentianaceae)." In Handbook of 200 Medicinal Plants, 1699–707. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-16807-0_176.

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Timilsina, Bishnu, Rabindra Parajuli, Dilli Prasad Rijal, Ripu M. Kunwar, Hammad Ahmad Jan, Wahid Hussain, Rainer W. Bussmann, and Narel Y. Paniagua-Zambrana. "Swertia angustifolia Burkill Swertia chirayita Buch.-Ham. ex C.B. Clarke Swertia cordata (G.Don) Clarke Swertia petiolata D. Don Gentianaceae." In Ethnobotany of the Himalayas, 1–12. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-45597-2_237-1.

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Jan, Hammad Ahmad, Wahid Hussain, Rainer W. Bussmann, and Narel Y. Paniagua-Zambrana. "Swertia angustifolia Burkill Swertia chirayita Buch.-Ham. ex C.B. Clarke Swertia cordata (G.Don) Clarke Swertia petiolata D. Don Gentianaceae." In Ethnobotany of the Himalayas, 1–10. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-45597-2_237-2.

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Jan, Hammad Ahmad, Wahid Hussain, Rainer W. Bussmann, and Narel Y. Paniagua-Zambrana. "Swertia angustifolia Burkill Swertia chirayita Buch.-Ham. ex C.B. Clarke Swertia cordata (G. Don) Clarke Swertia petiolata D. Don Gentianaceae." In Ethnobotany of the Himalayas, 1943–52. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-57408-6_237.

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Dhyani, Praveen, Lalit Giri, Eshita Sharma, and Priyanka Sati. "Swertia chirayita, an Endangered Anti-diabetic Plant: Trends in Biotechnological Interventions." In Biotechnology of Anti-diabetic Medicinal Plants, 133–51. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-3529-8_6.

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Meena, Poonam, Sampat Nehra, and P. C. Trivedi. "Anthology of Chemical Diversity of Bioactive Molecules and Therapeutics of the Genus Swertia chirayita (Roxb. ex Flem.) Karsten (Syn. Gentiana chirayita Roxb. ex Flem.)." In Bioactives and Pharmacology of Medicinal Plants, 105–20. Boca Raton: Apple Academic Press, 2022. http://dx.doi.org/10.1201/9781003281658-8.

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Chaudhuri, Rituparna Kundu, and Dipankar Chakraborti. "Bioactive Compounds from In-Vitro Culture of Swertia Chirayita (Roxb. Ex Flem.) Karsten: Identification and Quantification." In Plant-Based Functional Foods and Phytochemicals, 311–34. Series statement: Innovations in plant science for better health : from soil to fork: Apple Academic Press, 2020. http://dx.doi.org/10.1201/9781003055419-10.

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Conference papers on the topic "Swertia chirayita"

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Rutz, Adriano, Pascale Deneulin, Ivano Tonutti, Benoît Bach, and Jean-Luc Wolfender. "Untargeted chemical and sensory characterization of Swertia chirayita: a bitter case study." In GA – 69th Annual Meeting 2021, Virtual conference. Georg Thieme Verlag, 2021. http://dx.doi.org/10.1055/s-0041-1736968.

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