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Journal articles on the topic "SusC"

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Cho, Kyu Hong, and Abigail A. Salyers. "Biochemical Analysis of Interactions between Outer Membrane Proteins That Contribute to Starch Utilization byBacteroides thetaiotaomicron." Journal of Bacteriology 183, no. 24 (December 15, 2001): 7224–30. http://dx.doi.org/10.1128/jb.183.24.7224-7230.2001.

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ABSTRACT An early step in the utilization of starch by Bacteroides thetaiotaomicron is the binding of starch to the bacterial surface. Four starch-associated outer membrane proteins of B. thetaiotaomicron that have no starch-degrading activity have been identified. Two of these, SusC and SusD, have been shown by genetic analysis to be required for starch binding. In this study, we provide the first biochemical evidence that these two proteins interact physically with each other. Both formaldehyde cross-linking and nondenaturing gel electrophoresis experiments showed that SusC and SusD interact to form a complex. Two other proteins encoded by genes in the same operon, SusE and SusF, proved not to be essential for starch utilization and actually decreased starch binding when they were present along with SusC and SusD. Consistent with this, nondenaturing gel analysis revealed that in a strain producing SusC, SusD, and SusE, the SusCD complex was partially destabilized. The strain producing SusC, SusD, and SusE also grew more slowly on starch than a strain producing SusC, SusD, SusE, and SusF (μmax, 0.29 and 0.37/h, respectively). Thus, SusE appears to interact with the SusCD complex. SusE also interacts with SusF, because SusE was less susceptible to proteinase K digestion when SusF was present, and nondenaturing gel analysis detected a complex formed by these two proteins. Our results indicate that SusC, SusD, SusE, and SusF form a protein complex in the outer membrane but that SusE and SusF are dispensable members of this complex.
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Shipman, Joseph A., James E. Berleman, and Abigail A. Salyers. "Characterization of Four Outer Membrane Proteins Involved in Binding Starch to the Cell Surface ofBacteroides thetaiotaomicron." Journal of Bacteriology 182, no. 19 (October 1, 2000): 5365–72. http://dx.doi.org/10.1128/jb.182.19.5365-5372.2000.

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ABSTRACT Bacteroides thetaiotaomicron, a gram-negative obligate anaerobe, utilizes polysaccharides by binding them to its cell surface and allowing cell-associated enzymes to hydrolyze them into digestible fragments. We use the starch utilization system as a model to analyze the initial steps involved in polysaccharide binding and breakdown. In a recent paper, we reported that one of the outer membrane proteins involved, SusG, had starch-degrading activity but was not sufficient for growth on starch. Moreover, SusG alone did not have detectable starch binding activity. Previous studies have shown that starch binding is essential for starch utilization. In this paper, we report that four other outer membrane proteins, SusC through SusF, are responsible for starch binding. Results of 14C-starch binding assays show that SusC and SusD both contribute a significant amount of starch binding. SusE also appears to contribute substantially to starch binding. Using affinity chromatography, we show in vitro that these Sus proteins interact to bind starch. Moreover, protease accessibility of either SusC or SusD greatly increased when one was expressed without the other. This finding supports the hypothesis that SusC and SusD interact in the outer membrane. Evidence from additional protease accessibility studies suggests that SusC, SusE, and SusF are exposed on the cell surface. Our results demonstrate that SusC and SusD act as the major starch binding proteins on the cell surface, with SusE enhancing binding. SusF's role in starch utilization has yet to be determined, although the fact that starch protected it from proteolytic attack suggests that it does bind starch.
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Nakayama-Imaohji, Haruyuki, Hideki Hirakawa, Minoru Ichimura, Shin Wakimoto, Satoru Kuhara, Tetsuya Hayashi, and Tomomi Kuwahara. "Identification of the Site-Specific DNA Invertase Responsible for the Phase Variation of SusC/SusD Family Outer Membrane Proteins in Bacteroides fragilis." Journal of Bacteriology 191, no. 19 (July 31, 2009): 6003–11. http://dx.doi.org/10.1128/jb.00687-09.

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ABSTRACT The human gut microbe Bacteroides fragilis can alter the expression of its surface molecules, such as capsular polysaccharides and SusC/SusD family outer membrane proteins, through reversible DNA inversions. We demonstrate here that DNA inversions at 12 invertible regions, including three gene clusters for SusC/SusD family proteins, were controlled by a single tyrosine site-specific recombinase (Tsr0667) encoded by BF0667 in B. fragilis strain YCH46. Genetic disruption of BF0667 diminished or attenuated shufflon-type DNA inversions at all three susC/susD genes clusters, as well as simple DNA inversions at nine other loci, most of which colocalized with susC/susD family genes. The inverted repeat sequences found within the Tsr0667-regulated invertible regions shared the consensus motif sequence AGTYYYN4GDACT. Tsr0667 specifically mediated the DNA inversions of 10 of the 12 regions, even under an Escherichia coli background when the invertible regions were exposed to BF0667 in E. coli cells. Thus, Tsr0667 is an additional globally acting DNA invertase in B. fragilis, which probably involves the selective expression of SusC/SusD family outer membrane proteins.
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Chen, Chi-Ming. "A soft fixed Ppoint theorem of the weakly soft susc-contractions." Filomat 36, no. 8 (2022): 2583–90. http://dx.doi.org/10.2298/fil2208583c.

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In this article, we introduce a new notion of weakly soft susc-contraction in soft metric spaces and prove a soft fixed point theorem which assure the existence of soft fixed points for the type of weakly soft susc-contraction. Our results generalize many recent soft fixed point results in the literature.
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Maus, Irena, Tom Tubbesing, Daniel Wibberg, Robert Heyer, Julia Hassa, Geizecler Tomazetto, Liren Huang, et al. "The Role of Petrimonas mucosa ING2-E5AT in Mesophilic Biogas Reactor Systems as Deduced from Multiomics Analyses." Microorganisms 8, no. 12 (December 17, 2020): 2024. http://dx.doi.org/10.3390/microorganisms8122024.

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Members of the genera Proteiniphilum and Petrimonas were speculated to represent indicators reflecting process instability within anaerobic digestion (AD) microbiomes. Therefore, Petrimonas mucosa ING2-E5AT was isolated from a biogas reactor sample and sequenced on the PacBio RSII and Illumina MiSeq sequencers. Phylogenetic classification positioned the strain ING2-E5AT in close proximity to Fermentimonas and Proteiniphilum species (family Dysgonomonadaceae). ING2-E5AT encodes a number of genes for glycosyl-hydrolyses (GH) which are organized in Polysaccharide Utilization Loci (PUL) comprising tandem susCD-like genes for a TonB-dependent outer-membrane transporter and a cell surface glycan-binding protein. Different GHs encoded in PUL are involved in pectin degradation, reflecting a pronounced specialization of the ING2-E5AT PUL systems regarding the decomposition of this polysaccharide. Genes encoding enzymes participating in amino acids fermentation were also identified. Fragment recruitments with the ING2-E5AT genome as a template and publicly available metagenomes of AD microbiomes revealed that Petrimonas species are present in 146 out of 257 datasets supporting their importance in AD microbiomes. Metatranscriptome analyses of AD microbiomes uncovered active sugar and amino acid fermentation pathways for Petrimonas species. Likewise, screening of metaproteome datasets demonstrated expression of the Petrimonas PUL-specific component SusC providing further evidence that PUL play a central role for the lifestyle of Petrimonas species.
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Zhu, Yongtao, Kurt J. Kwiatkowski, Tengteng Yang, Sampada S. Kharade, Constance M. Bahr, Nicole M. Koropatkin, Weifeng Liu, and Mark J. McBride. "Outer membrane proteins related to SusC and SusD are not required for Cytophaga hutchinsonii cellulose utilization." Applied Microbiology and Biotechnology 99, no. 15 (April 7, 2015): 6339–50. http://dx.doi.org/10.1007/s00253-015-6555-8.

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Eichenhofer, Wolfgang. "Etymologisches im Lexicon romontsch cumparativ (LRC)." Ladinia 44 (2020): 163–240. http://dx.doi.org/10.54218/ladinia.44.163-240.

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Chësc articul se basëia en gran pert sön la storia linguistica dl sursilvan y mostra sö svilups de fonems vocalics y consonantics dal latin o dal todësch al ­romanc. Te chësta manira desmostrel, ciodí che tröpes indicaziuns etimologiches dl ­Lexicon romontsch cumparativ sursilvan – tudestg n’é nia da podëi azeté. Ince morfems da susc o liá vëgn descric cun le fin da mëte apost deplü derivaziuns dl lexicon. Analises de nia püc lessems mostra sö coche certes parores é rovades tla Surselva. Por stlü jö ciafon na lîta de d’atri lemesc dl LRC, pro chi ch’al é gnü fat la coreziun dles indicaziuns sön süa origina.
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DÉJARDIN, Annabelle, Lubomir N. SOKOLOV, and Leszek A. KLECZKOWSKI. "Sugar/osmoticum levels modulate differential abscisic acid-independent expression of two stress-responsive sucrose synthase genes in Arabidopsis." Biochemical Journal 344, no. 2 (November 24, 1999): 503–9. http://dx.doi.org/10.1042/bj3440503.

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Sucrose synthase (Sus) is a key enzyme of sucrose metabolism. Two Sus-encoding genes (Sus1 and Sus2) from Arabidopsis thaliana were found to be profoundly and differentially regulated in leaves exposed to environmental stresses (cold stress, drought or O2 deficiency). Transcript levels of Sus1 increased on exposure to cold and drought, whereas Sus2 mRNA was induced specifically by O2 deficiency. Both cold and drought exposures induced the accumulation of soluble sugars and caused a decrease in leaf osmotic potential, whereas O2 deficiency was characterized by a nearly complete depletion in sugars. Feeding abscisic acid (ABA) to detached leaves or subjecting Arabidopsis ABA-deficient mutants to cold stress conditions had no effect on the expression profiles of Sus1 or Sus2, whereas feeding metabolizable sugars (sucrose or glucose) or non-metabolizable osmotica [poly(ethylene glycol), sorbitol or mannitol] mimicked the effects of osmotic stress on Sus1 expression in detached leaves. By using various sucrose/mannitol solutions, we demonstrated that Sus1 was up-regulated by a decrease in leaf osmotic potential rather than an increase in sucrose concentration itself. We suggest that Sus1 expression is regulated via an ABA-independent signal transduction pathway that is related to the perception of a decrease in leaf osmotic potential during stresses. In contrast, the expression of Sus2 was independent of sugar/osmoticum effects, suggesting the involvement of a signal transduction mechanism distinct from that regulating Sus1 expression. The differential stress-responsive regulation of Sus genes in leaves might represent part of a general cellular response to the allocation of carbohydrates during acclimation processes.
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Barbero-Herranz, Raquel, María Garriga-García, Ana Moreno-Blanco, Esther Palacios, Pedro Ruiz-Sala, Saioa Vicente-Santamaría, Sinziana Stanescu, et al. "The Role of the Gut Microbiota in Sanfilippo Syndrome’s Physiopathology: An Approach in Two Affected Siblings." International Journal of Molecular Sciences 25, no. 16 (August 14, 2024): 8856. http://dx.doi.org/10.3390/ijms25168856.

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Sanfilippo syndrome, or mucopolysaccharidosis type III (MPS III), is a rare lysosomal disease caused by congenital enzymatic deficiencies in heparan sulfate (HS) degradation, leading to organ dysfunction. The most severe hallmark of MPS III comprises neurological alterations, although gastrointestinal symptoms (GISs) have also been shown to be relevant in many patients. Here, we explored the contribution of the gut microbiota to MPS III GISs. We analyzed the composition and functionality of the gut microbiota in two MPS III siblings with the same mutation (c.544C > T, c.1080delC, in the SGSH gene) and the same diet, but with differences in their GISs, including recurrent diarrhea in one of them. Using 16S sequencing, we observed that the MPS III patients exhibited decreased alpha diversity and a lower abundance of Lachnospiraceae and Bifidobacteriaceae accompanied by a higher abundance of the Ruminococcaceae and Rikenellaceae families than the healthy control subjects. Comparing siblings, we found an increased abundance of Bacteroidaceae and a lower abundance of Ruminococcaceae and Akkermansiaceae in the GIS-free patient. This patient also had a higher relative abundance of Sus genes (SusA, SusB, SusE, and SusG) involved in glycosaminoglycan metabolism. We found higher HS levels in the stool of the two MPS III patients than in healthy volunteers, particularly in the patient with GISs. Functionally, whole fecal metabolites from the patient with GISs induced oxidative stress in vitro in healthy monocytes. Finally, the Bacteroides thetaiotaomicron strain isolated from MPS III stool samples exhibited HS degradation ability. Overall, our results reveal different microbiota compositions and functionalities in MPS III siblings, who exhibited differential gastrointestinal symptomatology. Our study may serve as a gateway to explore the impact of the gut microbiota and its potential to enhance the quality of life in Sanfilippo syndrome patients.
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McBride, Mark J., Gary Xie, Eric C. Martens, Alla Lapidus, Bernard Henrissat, Ryan G. Rhodes, Eugene Goltsman, et al. "Novel Features of the Polysaccharide-Digesting Gliding Bacterium Flavobacterium johnsoniae as Revealed by Genome Sequence Analysis." Applied and Environmental Microbiology 75, no. 21 (August 28, 2009): 6864–75. http://dx.doi.org/10.1128/aem.01495-09.

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ABSTRACT The 6.10-Mb genome sequence of the aerobic chitin-digesting gliding bacterium Flavobacterium johnsoniae (phylum Bacteroidetes) is presented. F. johnsoniae is a model organism for studies of bacteroidete gliding motility, gene regulation, and biochemistry. The mechanism of F. johnsoniae gliding is novel, and genome analysis confirms that it does not involve well-studied motility organelles, such as flagella or type IV pili. The motility machinery is composed of Gld proteins in the cell envelope that are thought to comprise the “motor” and SprB, which is thought to function as a cell surface adhesin that is propelled by the motor. Analysis of the genome identified genes related to sprB that may encode alternative adhesins used for movement over different surfaces. Comparative genome analysis revealed that some of the gld and spr genes are found in nongliding bacteroidetes and may encode components of a novel protein secretion system. F. johnsoniae digests proteins, and 125 predicted peptidases were identified. F. johnsoniae also digests numerous polysaccharides, and 138 glycoside hydrolases, 9 polysaccharide lyases, and 17 carbohydrate esterases were predicted. The unexpected ability of F. johnsoniae to digest hemicelluloses, such as xylans, mannans, and xyloglucans, was predicted based on the genome analysis and confirmed experimentally. Numerous predicted cell surface proteins related to Bacteroides thetaiotaomicron SusC and SusD, which are likely involved in binding of oligosaccharides and transport across the outer membrane, were also identified. Genes required for synthesis of the novel outer membrane flexirubin pigments were identified by a combination of genome analysis and genetic experiments. Genes predicted to encode components of a multienzyme nonribosomal peptide synthetase were identified, as were novel aspects of gene regulation. The availability of techniques for genetic manipulation allows rapid exploration of the features identified for the polysaccharide-digesting gliding bacteroidete F. johnsoniae.
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Dissertations / Theses on the topic "SusC"

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Li, Xiaoqian. "Caractérisation et ingénierie de transporteurs d'oligosaccharides." Electronic Thesis or Diss., Université de Toulouse (2023-....), 2024. http://www.theses.fr/2024TLSEI008.

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Les mammifères hébergent des communautés microbiennes très diverses. Parmi celles-ci, le microbiote intestinal joue un rôle crucial dans la santé de l’hôte. Les bactéries intestinales utilisent des polysaccharides et oligosaccharides variés comme principales sources de carbone, en utilisant des systèmes protéiques complexes pour dégrader ces substrats en monosaccharides assimilables. Les bactéries du phylum Bacteroidota sont parmi les plus abondantes dans les microbiomes intestinaux des mammifères. Elles produisent une série de protéines nécessaires à la détection, à la capture, au transport et à la dégradation des polysaccharides et oligosaccharides. Ces systèmes complexes sont codés par des loci dédiés à l'utilisation des polysaccharides (PUL). A la surface cellulaire, les protéines de liaison aux glycanes (SGBPs) jouent un rôle majeur dans l’efficacité de capture des polysaccharides et des oligosaccharides entourant les cellules, offrant ainsi aux Bacteroidota un avantage compétitif dans la colonisation de leurs habitats. . Dans ce travail de thèse, nous nous sommes concentrés sur la caractérisation et l'ingénierie des transporteurs de bactéries du phylum Bacteroidota, en particulier leurs composants SGBPs, isses des microbiomes digestifs humains et bovins. L'objectif était d'élucider les relations structure-fonction des différents éléments protéiques de ces transporteurs impliqués dans l'utilisation des polysaccharides d’origine alimentaire ou microbiennne. Nous avons tout d’abord caractérisé la fonction et la structure cristallographique d’une protéine de type SusD (appelée ici F5_SusD-like) codée par un PUL provenant d’un Bacteroides non cultivé de l’intestin humain, et qui est conservé chez Bacteroides vulgatus, une espèce dominante dans le microbiote intestinal. Malgré son incapacité à se lier aux xylooligosaccharides (XOS), qui sont pourtant les substrats ciblés par le F5_PUL, F5_SusD est essentiel à la fonctionnalité du transport. L'analyse structurale a révélé des boucles désordonnées et des résidus clés mal alignés, qui pourraient être responsables de l'incapacité de cette protéine de type SGBP à se lier aux XOS. Dans un second temps, nous avons étudié la spécificité des transporteurs F5_SusC/D et F5_MFS vis-à-vis des XOS en introduisant une β-mannosidase dans le périplasme des souches recombinantes d’E. coli produisant ces transporteurs. En utilisant des variants du locus F5 précédemment construits par Tauzin et al., nous avons complété le système d'utilisation des oligosaccharides de F5 avec l'enzyme BT_0458 de la famille CAZy GH2. Nos données préliminaires suggèrent que les transporteurs du clone métagénomique F5 ne peuvent pas internaliser le mannotriose, indiquant une probable stricte spécificité de ces systèmes vis-à-vis des XOS. Par la suite, nous avons exploré le potentiel de l’évolution adaptative en laboratoire (ALE) pour l’ingénierie du système recombinant d’utilisation des XOS chez E. coli. Cette étude préliminaire indique que l’évolution in cellulo pourrait servir à améliorer les fonctions de transporteurs recombinants chez E. coli et à approfondir l’étude de leurs relations structure-fonction sous pression évolutive. Enfin, nous avons caractérisé une autre protéine de type SusD (appelée 41O1_SusD) codée par un locus d'utilisation de β-glucanes et provenant d'un clone métagénomique isolé du microbiome du rumen bovin. La caractérisation fonctionnelle de cette protéine a montré que 41O1_SusD présente une affinité de liaison pour les β-1,3-glucanes ramifiés par des liaisons β-1,6. Une comparaison structurale avec des protéines homologues a permis de mettre en évidence des motifs similaires de reconnaissance du substrat, impliquant trois résidus tryptophane. Ces résultats ont permis de progresser dans la compréhension du rôle joué par les protéines de type SusD dans l’utilisation des substrats issus de la paroi cellulaire végétale et/ou d’origine fongique dans le rumen bovin
Mammals host very diverse microbial communities. Among these, the gut microbiota plays a crucial role in host health. Gut bacteria utilize various polysaccharides and oligosaccharides as carbon sources, using complex protein machineries to degrade these substrates into assimilable monosaccharides. Bacteroidota represents one of the dominant phyla in mammal gut microbiomes. They produce a series of proteins necessary for the sensing, capture, transport and degradation of polysaccharides and oligosaccharides. These complex machineries are encoded by polysaccharide utilization loci (PULs). Among the proteins encoded by PULs, cell surface glycan-binding proteins (SGBPs) are essential for the efficient capture of substrates surrounding the cells. In this thesis work, we focused on the characterization and engineering of Bacteroidota transporters, in particular their SGBP components, identified from the human and bovine gut microbiomes. The aim was to elucidate the structure-function relationships of the different protein elements of these transporters, involved in the utilization of dietary or microbial glycans in gut microbiomes. We first characterized the function and crystallographic structure of a SusD-like protein (referred to F5_SusD-like here) encoded by a xylooligosaccharide (XOS) PUL from an uncultured human gut Bacteroides species, which is conserved in the prominent Bacteroides vulgatus species. Despite its inability to bind to XOS, that are the cognate substrates of the F5_PUL, the F5_SusD-like protein is essential for the uptake functionality. Structural analysis revealed disordered loops and misaligned key residues, which could be responsible for the inability of this SGBP-like protein to bind XOS. Then, we investigated the specificity of F5_SusC/D and F5_MFS transporters towards XOS by introducing aβ-mannosidase into the periplasm of the recombinant E. coli strains harboring these transporters. This approach aimed at determining if the transporters could uptake mannotriose, which would be degraded to monosaccharides by the β-mannosidase and support E. coli growth. Using F5 variants previously constructed by Tauzin et al., we complemented the F5 oligosaccharide utilization system with the BT_0458 β-mannosidase from the GH2 CAZy family. Our preliminary data suggest that the F5 transporters cannot recognize and transport mannotriose, indicating a probable strict specificity towards XOS. Subsequently, we explored the potential of adaptive laboratory evolution (ALE) to engineer the recombinant F5_XOS utilization pathway in E. coli. After serial sub-cultures of the F5_XOS containing E. coli strains, the mutation rates and positions were assessed by next-generation sequencing. This preliminary study indicated that ALE could serve to improve transporter functions and provided the basis for further investigation of the structure-function relationships of oligosaccharide transporters under evolutionary pressures. Finally, we characterized another SusD-like protein (referred to 41O1_SusD) encoded by a β-glucan utilization locus from a metagenomic clone isolated from the bovine rumen microbiome. Functional characterization showed that the 41O1_SusD-like protein exhibits binding affinity for β-1,6 branched β-1,3-glucans. Structural comparison with homolog SusD-like proteins highlighted a similar pattern of substrate recognition, involving three tryptophan residues. Our findings provided advances in the understanding of the role played by SusD-like proteins in plant cell wall and/or fungal polysaccharide utilization in the cow rumen. Overall, this thesis generated advances in the understanding of the structure-function relationships of SusD-like proteins. In the long term, the findings will contribute to the development of potential applications in synthetic biology and microbial engineering for enhanced polysaccharide utilization
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Carmo, Fabricio Marques do. "Um estudo sobre a supersimetria no contexto da mecânica quântica." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/43/43134/tde-29092011-155358/.

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Usando as Regras de Soma da QCD, testamos se a nova estrutura estreita, X(4350) recentemente observada pela Colaboração Belle, pode ser descrita como um estado molecular D8D80 exótico JPC = 1+. Consideramos as contribuições dos condensados de dimensão oito, trabalhamos com os termos dominantes em 8 mantendo os termos lineares na massa do quark estranho m8. A massa obtida é igual a mD8D80 = (5.05±0.19) GeV. Consideramos também uma corrente molecular 1+, DD0 e obtemos mDD0 = (4.92 ± 0.08) GeV. Concluímos que não é possível descrever a estrutura X(4350) como um estado molecular 1+ D8D80.
Using the QCD sum rules we test if the new narrow structure, the X(4350) recently observed by the Belle Collaboration, can be described as a JPC = 1+ exotic D8D80 molecular state. We consider the contributions of condensates up to dimension eight, we work at leading order in s and we keep terms which are linear in the strange quark mass ms. The mass obtained for such state is mD8D80 =(5.05 ± 0.19) GeV. We also consider a molecular 1+, DD0 current and we obtain mDD0 = (4.92 ± 0.08) GeV. We conclude that it is not possible to describe the X(4350) structure as a 1+ D8D80 molecular state.
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Abulaiti, Yiming. "Search for Direct Top Squark Pair Production with the ATLAS Experiment and Studies of the Primary Vertex Reconstruction Performance." Licentiate thesis, Stockholms universitet, Fysikum, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-105746.

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The ATLAS detector is one of the two largest experiments installed at the Large Hadron Collider at CERN, the European Organization for Nuclear Research. During the first run, the ATLAS detector recorded data at centre of mass energies of 7 TeV and 8 TeV, enabling many precision measurements and new physics searches. One important task in ATLAS is measuring the primary vertex, the interaction point of the hardest proton-proton collision in an event. In this thesis, a study of the primary vertex reconstruction performance in data and simulated events using $t\bar{t}$ and ${Z}$ events is presented. Within the statistics available, the performance in data and simulated events is found to be compatible. Motivated by the limitations of the Standard Model of particle physics, searches for supersymmetric particles are performed with the ATLAS experiment. No signal has been observed so far, and the results are used to set exclusion limits on the masses of the supersymmetric particles. As the exclusion limits are derived from analyses which each target only a single decay mode of a supersymmetric particle, the analyses might have lower sensitivity to more complex decay scenarios. In this thesis the sensitivity of one of the ATLAS searches for direct top squark pair production to models with more complex decay modes is investigated. The study concludes that the sensitivity to models where the top squark can decay via heavier charginos and neutralinos is lower than the sensitivity to models where only decays to the lightest chargino or neutralino are present.
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Hu, Bo. "SUSY phenomenology." Diss., Texas A&M University, 2004. http://hdl.handle.net/1969.1/1132.

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Supersymmetric extensions to the Standard Model (SM) have many interesting experimental consequences which can provide important hints to the physics beyond the SM. In this thesis, we first study the anomalous magnetic moment of the muon and show that a significant constraint on the parameter space can be obtained from its current experimental value. In the next topic, we study the CP violations in B -> phi K decays and show that the SM and the minimal supergravity model (mSUGRA) cannot account for the current experimental observation. We then show that all the data can be accommodated for a wide range of parameters in models with non-universal soft breaking left-right A terms. In our last topic, which is based on a Horava-Witten inspired model proposed by R. Arnowitt and B. Dutta, we extend their analysis to the full fermion sector of the SM and propose a new mechanism different from the usual see saw mechanism to generate small neutrino masses which are in good agreement with the current neutrino oscillation data.
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Wymant, Christopher Mark. "Signs of Susy." Thesis, Durham University, 2013. http://etheses.dur.ac.uk/7350/.

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After a brief introduction to 21st century fundamental physics suitable for the layman with a reasonable level of mathematical competence, I introduce the concept of unnaturalness in Standard Model electroweak symmetry breaking and Supersymmetry (Susy) as a potential solution. The optimally natural situation in Susy in light of the 2012 discovery of a Higgs boson is derived, namely that of almost maximal mixing, with the scalar top partners almost as light as can be. The discovery is also interpreted numerically in terms of the Next-to-Minimal Supersymmetric Standard Model, with greater emphasis placed on the visibility of the Higgs boson at the observed mass, i.e. on signal strengths. I introduce simple models of gauge-mediated Susy breaking (GMSB), and how their generalisation leads to a richer parameter space. I then investigate the role played by the mediation scale of GMSB: this is found to be as a control of the extent to which Yukawa couplings de-tune flavour-blind relations set by gauge couplings. Finally, issues relating to the discovery or exclusion of Susy at colliders are discussed. Bounds are derived for the masses of new particles from Large Hadron Collider searches for excesses of jets and missing energy without leptons, and compared to constraints arising from Higgs boson searches, for models of GMSB and the Constrained Minimal Supersymmetric Standard Model. I present a novel search strategy for new physics signatures with two neutral, stable particles, when such particles are produced by boosted decays. (Susy examples include models with light gravitinos, pseudo-goldstinos, singlinos or new photinos.) The method is shown to produce sharp mass peaks that enhance the visibility of the signal.
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Bennett, Stephen Thomas. "Aspects of gauge-string duality in SUSY and non-SUSY systems." Thesis, Swansea University, 2014. https://cronfa.swan.ac.uk/Record/cronfa42513.

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We study various aspects of type IIB supergravity backgrounds related to those of Klebanov-Strassler and Chamseddine-Volkov/Maldacena-Nunez, in the context of gauge-gravity duality. We first examine the structure which can be found in the family of supersymmetric solutions, and in particular the effect of adding flavour. We then turn to the problem of finding non-supersymmetric generalisations of the well-understood supersynnnetric solutions. Using a combination of analytic and numerical techniques we find a two-dimensional space of such solutions, corresponding to the baryonic branch of Klebanov-Strassler deformed by a SUSY-breaking irrelevant operator. We explore the parameter space in some detail, and find several interesting special cases and limits, including one in which supersymmetry is completely broken and unusual periodic behavior is present in the warp factors. Finally, we look in detail at some of the methods which can be used to probe the field theory corresponding to these kinds of backgrounds.
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Diethelm, Anna Margaretha. "Durch sin selbs unerstorben vichlichkeit hin zuo grosser loblichen heilikeit : Körperlichkeit in der Vita Heinrich Seuses /." Bern : P. Lang, 1988. http://catalogue.bnf.fr/ark:/12148/cb355796188.

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Bousquet, Margaux. "Musique à Suse et en Elam aux âges du Bronze et du Fer." Thesis, Lyon, 2020. http://www.theses.fr/2020LYSE2001.

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Les musiques des sociétés anciennes constituent un terrain de recherche passionnant et peu exploré dans le domaine de l’archéologie. Cet art éphémère et immatériel par excellence laisse en effet peu de traces susceptibles d’être étudiées par l’archéologue. Pourtant, les découvertes exceptionnelles d’instruments anciens, survenues dès les années 1920 dans le cimetière royal d’Ur ont suscité l’intérêt des chercheurs pour la musique du Proche-Orient ancien, participant à l’émergence d’une approche novatrice : l’archéomusicologie. Cette étude est consacrée à l’Élam, dans le Sud-Ouest iranien, région demeurée en retrait des études archéomusicologiques proche-orientales. L’objectif principal de cette étude est de proposer une restitution de l’instrumentarium élamite et d’en cerner à la fois l’évolution et les spécificités, tout en considérant les traits qui la rattachent à la sphère proche-orientale.En premier lieu, afin de dresser le cadre chronoculturel de ce travail, nous présentons une synthèse historiographique et un état des connaissances sur l’Élam, à partir de l’exploitation des données des fouilles anciennes et plus récentes, et des sources épigraphiques. Le cadre théorique de l’étude est ensuite défini à travers un exposé de l’histoire de la recherche sur les musiques anciennes, et plus particulièrement du Proche-Orient, soulignant les axes suivis pour traiter du phénomène musical. Ce bilan et le constat de la nature des données musicales disponibles pour la région – hétérogènes et disparates – permettent de définir notre approche archéomusicologique. Ainsi, le corpus rassemblé, principalement constitué de représentations musicales, nous a conduite à adopter une approche croisée et comparative, associant l’analyse de ces sources iconographiques, mais également des quelques vestiges d’instruments documentés, et des sources textuelles issues de cette région, entre le Chalcolithique et l’âge du Fer (fin du Ve - milieu du Ier millénaire avant J.-C.). La majorité de la documentation est issue de Suse, mais d’autres sites ont fourni des données musicales, pris en compte dans notre analyse (Choga Mish, Haft Tépé, Tchoga Zanbil, Tall-i Malyan, Kul-e Farah, Arjān et Ninive).Une part importante de notre analyse organologique réside dans la classification, la définition et l’identification des types d’instruments documentés par la culture matérielle de ces sites. L’inventaire détaillé et l’analyse des artefacts suso-élamites reliés à la sphère musicale ont ainsi abouti à la création d’un catalogue raisonné, richement illustré, qui constitue une base solide pour l’étude du phénomène musical de cette aire culturelle. Enfin, la synthèse issue du croisement des données iconographiques et historiques, et la comparaison avec les sources proche-orientales permet de proposer une restitution de l’instrumentarium suso-élamite, en soulignant ses spécificités et ses emprunts potentiels. Ces résultats offrent des pistes de réflexion sur l’évolution de ces instruments dans une perspective plus large, discutées à la fin de cette étude. Outre ces résultats, pour contribuer de façon concrète à une meilleure appréhension du phénomène musical dans l’Élam ancien, nous proposons également la reconstruction expérimentale d’un luth, dont l’objectif est non seulement de tester des hypothèses quant aux matériaux et techniques employées, mais également de fournir des pistes sérieuses pour aborder la dimension sonore des instruments du passé
The music from earliest societies is a fascinating but poorly explored archaeological field of research. This ephemeral and intangible art par excellence leaves meager remains for archaeologists’ scrutiny. However, the remarkable discoveries of extant instruments dated from the third millennium onward, excavated in the 1920s at the Royal Cemetery of Ur, have ignited a significant interest for ancient Near-Eastern music researchers, further contributing to the emergence of an innovative perspective that came to be known as archaeomusicology.This study is devoted to the land of Elam in South-Western Iran, a region that has been neglected in Near-Eastern archaeomusicology. The main objective of this work is to propose a restitution of the Elamite instrumentarium and to identify both its evolution and its specificities while considering features with which it relates to the Near-Eastern context.Firstly, in order to set the chrono-cultural framework of this research, we have proposed a historiographic synthesis running concurrently with the current status of our knowledge about Elam. This rests on the exploration of data from early and more recent excavations, as well as from epigraphic sources. Then, the theoretical framework of the study will be defined through a presentation of the research history of ancient music, and more particularly in the Near-East, highlighting themes addressing to the musical phenomenon. This review and the assessment of the nature of the musical data available for the region – heterogeneous and disparate – permits a definition of our archaeomusicological approach. Thus, the collected corpus, mainly consisting of musical representations, led us to adopt a cross and comparative approach, combining the analysis of these iconographic sources, but also of the few remains of documented instruments, and textual sources from this region, between the Chalcolithic and the Iron Age (late 5th - mid 1st millennium BC). Most of the documentation originates from Susa, but other sites have provided musical data, which were included in our analysis (Chogha Mish, Haft Tappeh, Chogha Zanbil, Tall-i Malyan, Kul-e Farah, Arjān and Nineveh).An important part of our organological analysis lies in the classification, definition and identification of the types of instruments documented in the material culture of these sites. The detailed inventory and analysis of Susan-Elamite artifacts related to the musical sphere have therefore led to the production of a richly illustrated catalogue, which constitutes a strong basis for the study of the musical phenomenon in this cultural area. Finally, the synthesis resulting from the crossing of iconographic and historical data, and the comparison with Near-Eastern sources has lead to a restitution of the Susan-Elamite instrumentarium, highlighting its specificities and potential borrowings. These results have provided food for thought about the evolution of these instruments from a broader perspective, discussed at the end of this research. In addition to these results, and in order to contribute in a concrete way to a better understanding of the musical phenomenon in ancient Elam, we have also proposed the experimental reconstruction of a lute, the objective of which being not only the testing of hypotheses about the materials and techniques used, but also providing a reliable way to address the matter of instrumental sound dimensions in the past
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Payet, Karine. "Cessions immobilières à Suse." Lyon 2, 2007. http://demeter.univ-lyon2.fr/sdx/theses/lyon2/2007/payet_k.

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Ville d’Iran occidental, située dans l’actuelle plaine du Khuzistan au pied des monts Zagros, Suse tout au long de son histoire a été soumise à la double influence de la Mésopotamie et de la confédération élamite. C’est dans ce contexte d’alternance que s’est développée une civilisation complexe et originale. La compréhension de celle-ci passe par l’examen des actes d’achat qui ont été découverts lors des fouilles dirigées par R. De Mecquenem, effectuées entre 1927 et 1928 dans le secteur dit de la «Ville royale». Le corpus se compose de 99 textes rédigés en akkadien, sur des tablettes d’argiles non cuites, dont une première publication a été réalisée par V. Scheil, assyriologue de la mission dès 1930. Cette étude s’organise autour de deux axes principaux. L’analyse juridique complète du formulaire permet tout d’abord de mettre en évidence son évolution ainsi que sa structuration progressive. La comparaison des schémas ainsi obtenus avec ceux des principaux sites mésopotamiens et de la ville élamite de Kabnak, a contribué à l’établissement de points de ressemblance et de dissemblance attestant de l’originalité du droit susien. A l’intérieur de cette analyse, une attention particulière a été portée aux clauses faisant intervenir des notions élamites, de manière à essayer d’en donner l’interprétation la plus précise possible. Le second volet est consacré à la détermination des caractéristiques de la société susienne à partir des données contenues dans ces contrats. Pour établir un portrait de la ville aussi réaliste que possible, les indications fournies par les achats ont été comparées et complétées par la consultation de la totalité du corpus juridique, ainsi que par l’étude des données archéologiques et ethnologiques. Le croisement de ces diverses sources offre une image satisfaisante des cadres de la société susienne pendant la première moitié du deuxième millénaire
Susa is a city of western Iran located in the current plain of Khuzestan close to the Zagros mounts. Throughout its history, Susa was subjected to the double influence of Mesopotamia and Elamite Confederation. In such a dual context has grown a complex and original civilization. This survey is based on the acts of purchase which were discovered during excavations realised by R. De Mecquenem, between 1927 and 1928, in the so-called «Royal City» area. The corpus is made up of 99 texts written in akkadian on uncooked clay shelves, a first publication of which was accomplished by V. Scheil, assyriologist of mission from 1930. This study is organized around two main parts. In a first part, the complete legal analysis of the contracts made it possible to highlight their evolution like their progressive structuring. The results have been compared with those known for the main Mesopotamians sites like for the elamite city of Kabnak. This showed some points of resemblance and dissimilarity attesting of the originality of the Susan right. Within this analysis, a detailed attention was paid to the contracts utilizing elamite concepts, so as to try to give the most precise possible interpretation of it. In a second part, the data contained in these contracts are analysed in order to obtain the characteristics of the Susan society. To establish a realistic portrait of the city, the indications provided by the purchases were compared and supplemented by the consultation of the whole legal corpus, and by the study of the archaeological and ethnological data. The crossing of these various sources offers a complete image of the Susan society during first half of the second millennium
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Payet, Karine Malbran-Labat Florence. "Cessions immobilières à Suse." [S. l.] : [s. n.], 2007. http://demeter.univ-lyon2.fr/sdx/theses/lyon2/2007/payet_k.

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Books on the topic "SusC"

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Teufel, Stefanie. Jetzt lerne ich SUSE Linux: Das Starter-Kit zu SUSE Linux 9.3 ; [Start ohne Vorwissen ; auf DVD: SUSE Linux 9.3 Special Edition]. Mu nchen/Germany: Markt und Technik, 2005.

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Nishimura, Takemasa. Susa Ikueikan: Bakumatsu shishi no manabiya. Yamaguchi-ken Abu-gun Susa-chō: Susa-chō Kyōiku Iinkai, 1994.

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Pogomu, Sese Burono, Alfa Ahmedi Silla, and Mamadi Ulare. Lako̳ sansie. Guinea?]: SNA, 2001.

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Pak, In-ho. Susi. [S.l: Chʻwiunhoe, 1985.

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Kungnip Kwahak Susa Yŏnʼguso (Korea), ed. Kwahak susa 30-yŏnsa. Sŏul Tʻŭkpyŏlsi: Kungnip Kwahak Susa Yŏnʼguso, 1986.

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Ulrich, Zeller, ed. 400 Jahre Suso-Bibliothek, 1604-2004. Bad Buchau: Federsee-Verlag, 2004.

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Har-Shefi, Avishar. Suse esh. Tel Aviv: Shoḳen, 2004.

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Nöstlinger, Christine. Echt Susi. 3rd ed. Wien: Dachs-Verlag, 1988.

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Hong, Kyŏng-hae. Susa illok. Kyŏnggi-do P'aju-si: Pogosa, 2018.

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aompiler, Han Po-gyŏng, ed. Susa panjang. Sŏul: Paeksan Sŏdang, 2020.

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Book chapters on the topic "SusC"

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Ugarte, Manuel Francisco, and Ricard Cervera. "Susac Syndrome." In Diagnostic Criteria in Autoimmune Diseases, 117–20. Totowa, NJ: Humana Press, 2008. http://dx.doi.org/10.1007/978-1-60327-285-8_22.

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Shenoy, Aravind, and Anirudh Prabhu. "Susy Explained." In CSS Framework Alternatives, 153–67. Berkeley, CA: Apress, 2018. http://dx.doi.org/10.1007/978-1-4842-3399-3_6.

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Kalka, Harald, and Gerhard Soff. "SUSY-Modelle." In Teubner Studienbücher Physik, 403–27. Wiesbaden: Vieweg+Teubner Verlag, 1997. http://dx.doi.org/10.1007/978-3-322-96701-5_11.

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Raby, Stuart. "SUSY GUTs." In Supersymmetric Grand Unified Theories, 43–52. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-55255-2_6.

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Ventura, Rachel E., and Steven L. Galetta. "Susac syndrome." In International Neurology, 73–74. Chichester, UK: John Wiley & Sons, Ltd, 2016. http://dx.doi.org/10.1002/9781118777329.ch24.

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Paschotta, R. "picosecond diode lasers." In RP Photonics Encyclopedia. RP Photonics AG, 2004. http://dx.doi.org/10.61835/suc.

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Paschotta, R. "absorptance." In RP Photonics Encyclopedia. RP Photonics AG, 2004. http://dx.doi.org/10.61835/sus.

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"supC." In Encyclopedia of Genetics, Genomics, Proteomics and Informatics, 1898. Dordrecht: Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6754-9_16361.

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Colopy, Cheryl. "Susu." In Dirty, Sacred Rivers. Oxford University Press, 2012. http://dx.doi.org/10.1093/oso/9780199845019.003.0021.

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“You’ll never get a dolphin with a digital camera,” Sushant Dey said, as we floated with the current on the Ganga. “They’re only on the surface for a second. By the time the shutter clicks, it’s already gone.” Early one morning in April 2007 I walked down to the bottom of a wide concrete stairway just outside Bhagalpur in the Indian state of Bihar to board an old fishing boat. Where the stairs met the river, the prow of the twenty-foot-long boat rested on the riverbank. A narrow plank, its ends positioned on the bank and the edge of the prow, allowed me to board. Sushant Dey and his brother Subhasis were taking me out to look for dolphins before the heat built up, when the dolphins might still be looking for food. Dolphins jump out of the water when they’re hunting, which they typically do early in the morning and again in the evening. The boatman tried repeatedly to start the wooden boat’s old diesel engine. Finally it coughed and caught; we chugged upriver a short way. He turned off the engine and we floated. After a few minutes, I heard a swish of water. A slick muscular body slipped back into the river before I could get a good look. A few minutes passed: another swish. I was looking in the wrong place and missed him. In spite of Sushant’s warning that my effort would be in vain, I tried again and again to catch a dolphin, pointing my camera to a likely spot on the opaque graygreen water where the animal might surface after I had missed a breach. Then I missed again. The Ganga flowed smoothly. It was about a half mile wide now, in the dry season. In the monsoon it grows to three miles wide and can be twenty-five feet higher in some places. The boatman took us to places where the dolphins were known to rest in the deep waters. I got half a dozen good glimpses as a dolphin surfaced briefly to breathe: an arc of dark gray, a shiny comma.
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"susi." In The Fairchild Books Dictionary of Textiles. Fairchild Books, 2021. http://dx.doi.org/10.5040/9781501365072.15922.

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Conference papers on the topic "SusC"

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Fontainha, Thalles C., Nilson J. Silva, and Claudia Cappelli. "SUSi-Carioca: Chatbot de pós-atendimento de consultas no SUS utilizando práticas de Linguagem Simples." In Anais Estendidos do Simpósio Brasileiro de Sistemas de Informação. Sociedade Brasileira de Computação (SBC), 2023. http://dx.doi.org/10.5753/sbsi_estendido.2023.229117.

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Os pacientes da rede de saúde pública brasileira têm dificuldades na obtenção de informações antes, durante e pós-consultas médicas. Mesmo quando recebem informações, a dificuldade em entendê-las impede o acesso destes pacientes aos serviços disponíveis. Este trabalho visa analisar este problema na visão do cidadão que é usuário dos sistemas de saúde da rede pública de saúde e propor uma aplicação que possa reduzir as dificuldades encontradas por este público. Considerando as práticas da Linguagem Simples, foi desenvolvido um sistema de chatbot com uso de inteligência artificial fazendo integração com o Whatsapp e simulando os dados dos usuários da rede do Sistema Único de Saúde, SUS buscando demonstrar o quanto o acesso a estas informações pode ser facilitado.
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Falkowski, Adam. "Little Susy and Twin Susy." In SUSY06: THE 14TH INTERNATIONAL CONFERENCE ON SUPERSYMMETRY AND THE UNIFICATION OF FUNDAMENTAL INTERACTIONS. AIP, 2007. http://dx.doi.org/10.1063/1.2735200.

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Lai, Yi-Hsiang, Hongbo Rong, Size Zheng, Weihao Zhang, Xiuping Cui, Yunshan Jia, Jie Wang, et al. "SuSy." In ICCAD '20: IEEE/ACM International Conference on Computer-Aided Design. New York, NY, USA: ACM, 2020. http://dx.doi.org/10.1145/3400302.3415644.

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Porod, Werner Rudolf. "SUSY overview." In An Alpine LHC Physics Summit. Trieste, Italy: Sissa Medialab, 2018. http://dx.doi.org/10.22323/1.330.0024.

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Nicolis, Stam. "Noisy SUSY." In Corfu Summer Institute 2022 "School and Workshops on Elementary Particle Physics and Gravity". Trieste, Italy: Sissa Medialab, 2023. http://dx.doi.org/10.22323/1.436.0108.

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Nielsen, Holger Bech, Silvio Pallua, and Predrag Dominis Prester. "Deriving SUSY." In International Europhysics Conference on High Energy Physics. Trieste, Italy: Sissa Medialab, 2001. http://dx.doi.org/10.22323/1.007.0308.

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OSWALD, CHARLES. "BLAST TESTING OF ENERGY ABSORBING CONNECTORS FOR BLAST RESISTANT DESIGN." In SUSI 2018. Southampton UK: WIT Press, 2018. http://dx.doi.org/10.2495/susi180061.

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Syngellakis, S. "Simple models for penetration of thick targets by rigid projectiles." In SUSI 2012. Southampton, UK: WIT Press, 2012. http://dx.doi.org/10.2495/su120061.

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Laczák, L. E., and G. Károlyi. "Parametric study for aircraft impact." In SUSI 2014. Southampton, UK: WIT Press, 2014. http://dx.doi.org/10.2495/susi140081.

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Liang, C. C., and L. G. Nam. "Comparative analysis of bus rollover protection under existing standards." In SUSI 2010. Southampton, UK: WIT Press, 2010. http://dx.doi.org/10.2495/su100041.

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Reports on the topic "SusC"

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Hinchliffe, I., F. E. Paige, E. Nagy, M. D. Shapiro, J. Soderqvist, and W. Yao. Precision SUSY measurements at LHC:Point 3. Office of Scientific and Technical Information (OSTI), November 1998. http://dx.doi.org/10.2172/6388.

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Strobbe, Nadja. Strong SUSY at ATLAS and CMS. Office of Scientific and Technical Information (OSTI), January 2019. http://dx.doi.org/10.2172/1570199.

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Paige, F. Toy simulation of ATLAS SUSY points. Office of Scientific and Technical Information (OSTI), May 1996. http://dx.doi.org/10.2172/264592.

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Herradón, Bernardo. Calpaína y sus inhibidores. Sociedad Española de Bioquímica y Biología Molecular (SEBBM), July 2011. http://dx.doi.org/10.18567/sebbmdiv_anc.2011.07.1.

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Vásquez Romero, Rodrigo Efrén, Hugo Humberto Ballesteros Chavarro, Nelly Carolina Ortega Flórez, William Dayam Maldonado Quintero, and Jorge Euclides Tello Durán. La colmena y sus productos. Corporación Colombiana de Investigación Agropecuaria - AGROSAVIA, 2012. http://dx.doi.org/10.21930/agrosavia.poster.2012.7.

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Hewett, JoAnne L. The Snowmass Points and Slopes: Benchmarks for SUSY Studies. Office of Scientific and Technical Information (OSTI), February 2002. http://dx.doi.org/10.2172/799000.

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Miller, James H. Middle Atlantic Bight Field Study: SUS Component. Fort Belvoir, VA: Defense Technical Information Center, September 1997. http://dx.doi.org/10.21236/ada634891.

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Toro, Jorge, ed. ¿Tardó Colombia en iniciar sus ciclos monetarios? Banco de la República, March 2024. http://dx.doi.org/10.32468/blog12032024.

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Con frecuencia los observadores económicos que hacen seguimiento a la política monetaria comparan las fechas de las decisiones de los ciclos de subidas o de bajadas de las tasas de interés entre países para establecer cuáles países se adelantaron y cuáles se retrasaron en sus decisiones. Esto podría ser correcto si los países tuvieran comportamientos económicos idénticos. Pero sabemos que no es así. Por esta razón, un juicio de esta naturaleza requiere un análisis más sofisticado, que no solo compare los calendarios, sino también el comportamiento de indicadores económicos claves al inicio de los ciclos de subidas o de bajadas de la tasa de interés de política (TPM) en cada país. Una reciente nota sobre ciclos monetarios publicada por los directores de la Junta Directiva del Banco de la República, Bibiana Taboada y Mauricio Villamizar, en compañía de Manuela Bernal, acomete esta compleja tarea.
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Cohen, Timothy. SUSY Simplified Models at 14, 33, and 100 TeV Proton Colliders. Office of Scientific and Technical Information (OSTI), November 2013. http://dx.doi.org/10.2172/1108343.

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Kongeter, Armin. Search for r-parity violating SUSY in the CDF multilepton channel. Office of Scientific and Technical Information (OSTI), November 1999. http://dx.doi.org/10.2172/1421482.

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