Dissertations / Theses on the topic 'Survival outcomes'
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Havercroft, William G. "Exploration of marginal structural models for survival outcomes." Thesis, University of Bristol, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.684750.
Full textCavalli, Maide Maria. "Predicting survival outcomes in Myeloma using surrogate markers." Doctoral thesis, Università di Catania, 2013. http://hdl.handle.net/10761/1394.
Full textLehr, Carli J. "Extremes of Age Decrease Survival After Lung Transplant." Case Western Reserve University School of Graduate Studies / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case152909506004063.
Full textRamchandani, Ritesh. "Rank-Based Methods for Survival Data With Multiple Outcomes." Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:23845423.
Full textBiostatistics
Meier, Amalia Sophia. "Discrete proportional hazards models for uncertain outcomes /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/9579.
Full textKernell, Kristina. "Cardiac disease in pregnancy and consequences for reproductive outcomes, comorbidity and survival." Doctoral thesis, Linköpings universitet, Avdelningen för kliniska vetenskaper, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-134854.
Full textDodd, Susanna. "Modelling departure from randomised treatment in randomised controlled trials with survival outcomes." Thesis, University of Liverpool, 2014. http://livrepository.liverpool.ac.uk/2006887/.
Full textKitajima, Toshihiro. "Impact of graft thickness reduction of left lateral segment on outcomes following pediatric living donor liver transplantation." Kyoto University, 2019. http://hdl.handle.net/2433/242356.
Full textRahman, M. S. "Validation measures for prognostic models for independent and correlated binary and survival outcomes." Thesis, University College London (University of London), 2012. http://discovery.ucl.ac.uk/1367069/.
Full textUnderhill, Andrea T. "Gender differences in traumatic brain injury outcomes survival, functional independence, and employment status /." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2008. https://www.mhsl.uab.edu/dt/2008p/underhill.pdf.
Full textMubanga, Mwenya. "Investigation of the management of tuberculous pericarditis (IMPI) registry : survival and outcomes sub-study." Master's thesis, University of Cape Town, 2012. http://hdl.handle.net/11427/6024.
Full textKaraesmen, Ezgi. "Genetic Associations with Survival Outcomes after Matched Unrelated Donor Allogeneic Hematopoietic Stem Cell Transplantation." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1587686582370275.
Full textGupta, Ruta. "Factors that Predict and Improve the Survival Outcomes of Head and Neck Cancer Patients." Thesis, The University of Sydney, 2020. https://hdl.handle.net/2123/24601.
Full textTsampalieros, Anne. "Inter-centre Variation in the Management of Kidney Transplant Recipients and Its Impact on Clinical Outcomes." Thesis, Université d'Ottawa / University of Ottawa, 2018. http://hdl.handle.net/10393/37266.
Full textReece, Mifanwy Mary. "Comparing outcomes of laparoscopic and open complete mesocolic excision for colon cancer." Thesis, The University of Sydney, 2021. https://hdl.handle.net/2123/27398.
Full textFidler, Miranda Marie. "Long-term adverse outcomes following five-year survival of cancer diagnosed before 40 years age." Thesis, University of Birmingham, 2016. http://etheses.bham.ac.uk//id/eprint/6638/.
Full textCheung, Li Chien. "Mixture models for left- and interval-censored data and concordance indices for composite survival outcomes." Thesis, The George Washington University, 2017. http://pqdtopen.proquest.com/#viewpdf?dispub=10259297.
Full textFor cost-effectiveness and efficiency, many large-scale general-purpose cohort studies are being assembled within health-care providers who use electronic health records. Two key features of such data are that incident disease is interval-censored between irregular visits and pre-existing (prevalent) disease is left-censored. Because prevalent disease is not always immediately diagnosed, some disease diagnosed at later visits are actually undiagnosed prevalent disease. I consider prevalent disease as a point mass at time zero for clinical applications where there is no interest in time of prevalent disease onset. I demonstrate that the naive Kaplan-Meier cumulative risk estimator underestimates risks at early time points and overestimates later risks. I propose a general family of mixture models that we call prevalence-incidence models. Parameters for parametric prevalence-incidence models, such as the logistic regression and Weibull survival (logistic-Weibull) model, are estimated by direct likelihood maximization or EM algorithm. Non-parametric methods are proposed to calculate cumulative risks for cases without covariates. I compare naive Kaplan-Meier, logistic-Weibull, and non-parametric estimates of cumulative risk in the cervical cancer screening program at Kaiser Permanente Northern California. Kaplan-Meier methods provided poor estimates while the logistic-Weibull model was a close fit to the non-parametric. My findings support use of logistic-Weibull models over Kaplan-Meier methods to develop risk estimates for informing U.S. risk-based cervical cancer screening guidelines. Harrell's c index is widely used to measure the accuracy in predicting univariate survival outcomes. However, survival outcomes relating to a disease of interest may show up in multiple endpoints of interest. I propose two extensions of Harrell's c index for composite survival outcomes that account for frequencies of occurrences and the severity/importance of the outcomes. A weighted C index is proposed for a disease process with multiple equally important endpoints, and a most severe comparable C index is proposed for a disease process with a rare primary outcome and a correlated secondary outcome. Asymptotic properties are derived based on theorems for U-statistics. In the simulation studies, my extensions gain efficiency and power in identifying true prognostic variables. I illustrate these novel concordance indices using the Epidemiology of Diabetes Intervention and Complications (EDIC) and the Diabetes Prevention Program (DPP) trials. In EDIC, the prognosis of diabetes patients at risk for multiple equally important microvascular complications are evaluated using the weighted C index. In DPP, patients with impaired glucose resistance (IGR) who may either progress to type II diabetes or regress to normal glucose resistance (NGR). The proposed most severe comparable index better evaluates the accuracy in predicting diabetes risk with the help of auxiliary NGR outcomes.
Spirko, Lauren Nicole. "Variable Selection and Supervised Dimension Reduction for Large-Scale Genomic Data with Censored Survival Outcomes." Diss., Temple University Libraries, 2017. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/466860.
Full textPh.D.
One of the major goals in large-scale genomic studies is to identify genes with a prognostic impact on time-to-event outcomes, providing insight into the disease's process. With the rapid developments in high-throughput genomic technologies in the past two decades, the scientific community is able to monitor the expression levels of thousands of genes and proteins resulting in enormous data sets where the number of genomic variables (covariates) is far greater than the number of subjects. It is also typical for such data sets to have a high proportion of censored observations. Methods based on univariate Cox regression are often used to select genes related to survival outcome. However, the Cox model assumes proportional hazards (PH), which is unlikely to hold for each gene. When applied to genes exhibiting some form of non-proportional hazards (NPH), these methods could lead to an under- or over-estimation of the effects. In this thesis, we develop methods that will directly address t
Temple University--Theses
Ramroth, Johanna Rankin. "Radiotherapy dose-fractionations and outcomes in cancer patients." Thesis, University of Oxford, 2017. http://ora.ox.ac.uk/objects/uuid:8c5a99de-7d8c-4b19-9a91-e6cf4efa7bd2.
Full textWebster, Elizabeth Natalie. "Health care Facilities as a Predictor of Breast Cancer Survival Rates." ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/6145.
Full textHsieh, Jeff Ching-Fu. "Bayesian statistical models for understanding health-related outcomes for women screened for breast cancer." Thesis, Queensland University of Technology, 2016. https://eprints.qut.edu.au/100033/1/Jeff%20Ching-Fu_Hsieh_Thesis.pdf.
Full textKvederienė, Rūta. "The impact of emergency care on severe pediatric trauma outcomes." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2012. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20121227_085948-00813.
Full textTraumos yra pagrindinė vaikų, paauglių ir jaunų suaugusiųjų mirties priežastis. Stebimas didžiulis skirtumas Europos Sąjungos (ES) šalyse lyginant mirštamumą nuo traumų. Lietuvoje didžiausias ES standartizuotas traumų mirčių dažnis (150.9 mirtys dėl traumų 100.000 gyventojų). Palyginimui: ES šalių vidurkis yra 41.4 mirtys dėl traumos 100.000 gyventojų, mažiausias standartizuotas traumų mirčių dažnis yra Olandijoje – 26.4 mirtys 100.000 gyventojų. Toks skirtumas nurodo potencialią galimybę sumažinti mirčių dėl traumų skaičių, naudojant visas priemones: tiek traumų prevenciją, tiek skubios pagalbos prieinamumą ir kokybę. Darbo tikslas – išanalizuoti vaikų, patyrusių sunkias traumas, ikihospitalinės pagalbos ir skubiosios pagalbos ligoninėje laiko bei apimties įtaką traumų išeitims, atliekant perspektyvinį tyrimą Vilniaus Universiteto Santariškių klinikų Vaikų ligoninėje bei Vilniaus Greitosios medicinos pagalbos stotyje. Rezultatai parodė, kad pagalbos lygis ikihospitaliniu laikotarpiu susijęs su išeitimi: pacientams, gavusiems aukštesnio lygio pagalbą traumos išeitys pagal Glazgo išeičių skalę buvo geresnės. Ilgesnis laikas nuo paciento atvežimo į ligoninę iki pirmos skubiosios intervencijos statistiškai patikimai koreliavo su blogesne traumos išeitimi. Apskaičiavus išgyvenamumo tikimybę (Ps) pagal traumos skalės pažeidimų sunkumo modelį (TRISS), 74 proc. mirčių dėl traumų pateko į netikėtų mirčių (Ps > 50 proc.) kategoriją. Kiekviena netikėta mirtis, identifikuota naudojant... [toliau žr. visą tekstą]
Dolgin, Natasha H. "Frailty and Outcomes in Liver Transplantation: A Dissertation." eScholarship@UMMS, 2016. https://escholarship.umassmed.edu/gsbs_diss/817.
Full textDolgin, Natasha H. "Frailty and Outcomes in Liver Transplantation: A Dissertation." eScholarship@UMMS, 2004. http://escholarship.umassmed.edu/gsbs_diss/817.
Full textWahlgren, Thomas. "High dose rate brachytherapy boost for localized prostate cancer : clinical and patient-reported outcomes/." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-931-9/.
Full textO'Daniel, Alyson J. "SOCIAL CATEGORIES AND HEALTH CARE OUTCOMES: AFRICAN AMERICAN WOMEN AND HIV SURVIVAL IN THE URBAN SOUTH." UKnowledge, 2010. http://uknowledge.uky.edu/gradschool_diss/92.
Full textFong, Sze-un Calvin. "Long-term outcomes of cataract surgery: visual acuity, survival, and incidence and progression of ocular pathology." Thesis, The University of Sydney, 2014. http://hdl.handle.net/2123/11434.
Full textBudryk, Michal, and Alice Schmuck. "How to Handle an Internal Venture? : The Effect of Relatedness on the Outcomes of Corporate Venturing." Thesis, Uppsala universitet, Företagsekonomiska institutionen, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-226610.
Full textSarnowski, Adam. "Management of the Open Apex Using a Bioceramic Apical Barrier: Success and Survival Rates at Virginia Commonwealth University." VCU Scholars Compass, 2019. https://scholarscompass.vcu.edu/etd/5765.
Full textDunn, Janet Audrey. "Development of an improved staging system to predict both survival and specific disease outcomes in multiple myeloma." Thesis, University of Birmingham, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.412762.
Full textHannon, James G. "Place Needs and Client Outcomes of Wilderness Experience Programs in Maine: A Descriptive-Interpretive Approach." Fogler Library, University of Maine, 2004. http://www.library.umaine.edu/theses/pdf/HannonJG2004.pdf.
Full textStrand, Linn Beate. "The influence of ambient temperature on birth outcomes in Brisbane, Australia." Thesis, Queensland University of Technology, 2011. https://eprints.qut.edu.au/47005/1/Linn_Beate_Strand.pdf.
Full textHamilton, Neil D. "Influences of first-line oral monotherapy on outcomes in Pulmonary Arterial Hypertension in association with Connective Tissue Disease." Thesis, University of Bradford, 2013. http://hdl.handle.net/10454/7322.
Full textKabaso, Mushota. "Using simulation and survival analysis to forecast outcomes and economic costs of the antiretroviral therapy programme in Zambia." Thesis, University of Southampton, 2015. https://eprints.soton.ac.uk/385233/.
Full textMorsheimer, Megan. "Survival, virological and immunological outcomes of HIV-infected children accessing ART at South African primary health care clinics." Master's thesis, University of Cape Town, 2013. http://hdl.handle.net/11427/10991.
Full textSouth Africa faces the world’s largest pediatric HIV epidemic. Combination antiretroviral therapy (ART) is the only effective treatment for HIV virus suppression. Pediatric HIV care has traditionally been provided in academic research and tertiary care facilities, however efforts to improve ART availability for children are ongoing through decentralization. Tygerberg Hospital physicians with training in pediatric HIV management are providing care in seven community-based primary health care (PHC) clinics in the greater Cape Town region. ART initiation and ongoing ART management for those down-referred from tertiary and district level facilities are provided. The HIV-related outcomes of this cohort have yet to be reported.
Licht, Amanda Abigail. "Private incentives, public outcomes: the role of target political incentives in the success of foreign policy." Diss., University of Iowa, 2010. https://ir.uiowa.edu/etd/700.
Full textHamilton, Neil David. "Influences of first-line oral monotherapy on outcomes in Pulmonary Arterial Hypertension in association with Connective Tissue Disease." Thesis, University of Bradford, 2013. http://hdl.handle.net/10454/7322.
Full textClaggett, Brian Lee. "Statistical Methods for Clinical Trials with Multiple Outcomes, HIV Surveillance, and Nonparametric Meta-Analysis." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10440.
Full textWang, Jiajia. "Assessment of the effects of maternal exposure to heatwave on birth outcomes in Brisbane, Australia." Thesis, Queensland University of Technology, 2014. https://eprints.qut.edu.au/76289/1/Jiajia_Wang_Thesis.pdf.
Full textKhaddam, Sinan M. D. "Difference in outcomes between central airway lesions requiring stents and lesions that donot in patients with NSCLC." University of Cincinnati / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1553513958608363.
Full textHall, Thomas Charles. "A randomised control trial investigating the effects of parenteral fish oil on survival outcomes in critically ill patients with sepsis." Thesis, University of Leicester, 2015. http://hdl.handle.net/2381/32336.
Full textNishizaki, Daisuke. "Laparoscopic versus open surgery for locally advanced rectal cancer: five-year survival outcomes in a large, multicenter, propensity score matched cohort study." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/265186.
Full textTalikowska, Milena. "The relationship between the quality of cardiopulmonary resuscitation (CPR) performed by paramedics and survival outcomes from out-of-hospital cardiac arrest (OHCA)." Thesis, Curtin University, 2017. http://hdl.handle.net/20.500.11937/65985.
Full textOlsson, Christian. "Thoracic Aortic Surgery : Epidemiology, Outcomes, and Prevention of Cerebral Complications." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6899.
Full textMartel, Guillaume. "Evaluating Surgical Outcomes: A Systematic Comparison of Evidence from Randomized Trials and Observational Studies in Laparoscopic Colorectal Cancer Surgery." Thèse, Université d'Ottawa / University of Ottawa, 2012. http://hdl.handle.net/10393/20534.
Full textValentine, Thomas Robert. "Illness Perceptions and Psychological and Physical Health Outcomes in Non-Small Cell Lung Cancer: A Self-Regulatory Model Approach." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1594830809190808.
Full textDerwall, Matthias, Anne Brücken, Christian Bleilevens, Andreas Ebeling, Philipp Föhr, Rolf Rossaint, Karl B. Kern, Christoph Nix, and Michael Fries. "Doubling survival and improving clinical outcomes using a left ventricular assist device instead of chest compressions for resuscitation after prolonged cardiac arrest: a large animal study." BioMed Central Ltd, 2015. http://hdl.handle.net/10150/610308.
Full textOzcan, Berkay. "The effects of marital transitions and spousal characteristic on economic outcomes." Doctoral thesis, Universitat Pompeu Fabra, 2008. http://hdl.handle.net/10803/7251.
Full textEsta tesis tiene el objetivo de ampliar y perfeccionar nuestra comprensión de por qué y cómo la dinámica de pareja afecta cuatro críticos resultados económicos que están directamente realacionados con la desigualdad y la estratificación. Estos resultados son, respectivamente; ser autónomo, la oferta de trabajo, el ahorro de los hogares y la distribución del ingreso. A lo largo de la tesis, con la dinámica de pareja, concibo dos conceptos: en primer lugar implica formar parte de una pareja (es decir, tener una esposa/o con ciertas características) versus ser soltero/a y transiciones entre estos dos estados. Y la segunda se refiere a los cambios en el comportamiento de los esposos debido a un cambio de contexto, como un aumento en el riesgo de disolución de la pareja. Por consiguiente, analiza las implicaciones de estos dos conceptos en cada una de estas variables económicas. La tesis se utiliza una serie de grandes conjuntos de datos longitudinales de diferentes países (p.e. PSID, GSOEP, PHCE, Living in Ireland Survey) y estratégias econométricas. Estas características incluyen el análisis de supervivencia, las estimaciones de diff-en-diff, simulaciones y descomposiciones.
Abu, Hawa Ozien. "Religiosity and Patient Activation and Health Outcomes among Hospital Survivors of an Acute Coronary Syndrome." eScholarship@UMMS, 2019. https://escholarship.umassmed.edu/gsbs_diss/1025.
Full textYao, Siyuan. "Impact of imbalanced graft-to-spleen volume ratio on outcomes following living donor liver transplantation in an era when simultaneous splenectomy is not typically indicated." Kyoto University, 2020. http://hdl.handle.net/2433/253139.
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